OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Cellular Biochemistry is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Dual inhibition of MEK1/2 and MEK5 suppresses the EMT/migration axis in triple‐negative breast cancer through FRA‐1 regulation	102
Issue Information	58
HEPES‐buffering of bicarbonate‐containing culture medium perturbs lysosomal glucocerebrosidase activity	55
RETRACTION: “Okadaic acid promotes epithelial‐mesenchymal transition of hepatocellular carcinoma cells by inhibiting protein phosphatase 2A”	51
Retraction	44
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Retraction	39
The cell cycle‐related genes RHAMM, AURKA, TPX2, PLK1, and PLK4 are associated with the poor prognosis of breast cancer patients	33
Intrinsic factors behind long‐COVID: I. Prevalence of the extracellular vesicles	33
Myricitrin promotes osteogenesis and prevents ovariectomy bone mass loss via the PI3K/AKT signalling pathway	33
Optimization of production and characterization of a recombinant soluble human Cripto‐1 protein inhibiting self‐renewal of cancer stem cells	32
Retraction	30
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Withdrawal	27
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Gengnianchun Against H₂O₂‐Induced Oxidative Damage in KGN Cells via miR‐548m/FOXO3 Signaling	19
Retraction	19
Mcl‐1 is a Gatekeeper Molecule to Regulate the Crosstalk Between Ferroptotic Agent‐Induced ER Stress and TRAIL‐Induced Apoptosis	18
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Lactate‐Dependent HIF1A Transcriptional Activation Exacerbates Severe Acute Pancreatitis Through the ACSL4/LPCAT3/ALOX15 Pathway Induced Ferroptosis	18
Issue Information	18
RETRACTION to “Adipose Tissue‐Derived Stem Cells Inhibit Hypertrophic Scar (HS) Fibrosis via p38/MAPK Pathway”	18
Test title	17
Issue Information	17
Issue Information	17
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Metformin ameliorates mitochondrial damage induced by C9orf72 poly(GR) via upregulating AKT phosphorylation	16
Issue Information	16
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RETRACTION: Upregulation of LncRNA SnoRNA Host Gene 6 Regulates NUAK Family SnF1‐like Kinase‐1 Expression by Competitively Binding MicroRNA‐125b and Interacting with Snail1/2 in Bladder Cancer	15
Cover Image, Volume 125, Number 12, December 2024	15
Cover Image, Volume 125, Number 12, December 2024	15
Combined scaffold hopping, molecular screening with dynamic simulation to screen potent CRBN ligands	14
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Fangchinoline targets epithelial–mesenchymal transition process by modulating activation of multiple cell‐signaling pathways	14
Herkinorin negatively regulates NLRP3 inflammasome to alleviate neuronal ischemic injury through activating Mu opioid receptor and inhibiting the NF‐κB pathway	14
Bone morphogenetic protein 13 in hepatic stellate cells and hepatic fibrosis	14
Effective Targeting of Colorectal Cancer Stem Cells by Inducing Differentiation Mediated by Low‐Dose Vitamin C via β‐Catenin Retention in the Cell Membrane	13
Activation of heme oxygenase‐1 by laminar shear stress ameliorates high glucose‐induced endothelial cell and smooth muscle cell dysfunction	13
Cover Image, Volume 124, Number 5, May 2023	13
Unsulfated biotechnological chondroitin by itself as well as in combination with high molecular weight hyaluronan improves the inflammation profile in osteoarthritis in vitro model	13
The dyeing effect of acridine orange for multiple plasmid systems is sensitive to temperature	13
From nature to cancer therapy: Evaluating the Streptomyces clavuligerus secondary metabolites for potential protein kinase inhibitors	13
Miro1 functions as an inhibitory regulator of MFN at elevated mitochondrial Ca²⁺ levels	13
Targeting sterol alpha‐14 demethylase of Leishmania donovani to fight against leishmaniasis	13
Phosphorylated LASS2 inhibits prostate carcinogenesis via negative regulation of Wnt/β‐catenin signaling	13
BRG1 mediates epigenetic regulation of TNFα‐induced CCL2 expression in oral tongue squamous cell carcinoma cells	12
Discovery of novel tubulin inhibitors targeting taxanes site by virtual screening, molecular dynamic simulation, and biological evaluation	12
BAG3 induces α‐SMA expression in human fibroblasts and its over‐expression correlates with poorer survival in fibrotic cancer patients	12
In silico and structure‐based evaluation of deleterious mutations identified in human Chk1, Chk2, and Wee1 protein kinase	12
Physical exercise positively modulates nonalcoholic steatohepatitis‐related hepatic endoplasmic reticulum stress	12
Glyoxylate reductase/hydroxypyruvate reductase regulates the free d‐aspartate level in mammalian cells	12
Identification and functional analysis of the mitochondrial cysteine synthase TtCsa2 from Tetrahymena thermophila	12
Covidin, a possible new player between hepcidin and ferroportin in hypoxia and inflammation caused by COVID‐19	11
Umbilical cord MSC‐derived exosomes improve alveolar macrophage function and reduce LPS‐induced acute lung injury	11
C5aR2 receptor: The genomic twin of the flamboyant C5aR1	11
Spinal malformation − A biochemical analysis using congenital kyphosis rats	11

Function of normal oral mucosa revealed by single‐cell RNA sequencing	11
De Novo Rational Design of Peptide‐Based Protein–Protein Inhibitors (Pep‐PPIs) Approach by Mapping the Interaction Motifs of the PP Interface and Physicochemical Filtration: A Case on p25‐Cdk5‐Mediate	11
Immunoinformatics based designing a multi‐epitope vaccine against pathogenic Chandipura vesiculovirus	11
Differential effects of 5‐fluorouracil and oxaliplatin on autophagy in chemoresistant colorectal cancer cells	11
Toward effective Atg8‐based ATTECs: Approaches and perspectives	10
The mitochondrial calcium signaling, regulation, and cellular functions: A novel target for therapeutic medicine in neurological disorders	10
ZBM‐H‐induced activation of GRP78 ATPase promotes apoptosis via annexin A7 in A549 lung cancer cells	10
Effects of the pathological E200K mutation on human prion protein: A computational screening and molecular dynamics approach	10
Genetically engineered mouse models of FK506‐binding protein 5	10
Network‐Based Transcriptome Analysis Reveals FAM3C as a Novel Potential Biomarker for Glioblastoma	10
Novel protein products encoded by upstream open reading frames of the MYCN gene in pediatric embryonal tumors	10
VEGFR3 suppression through miR‐1236 inhibits proliferation and induces apoptosis in ovarian cancer via ERK1/2 and AKT signaling pathways	10
NUSAP1 regulates mouse oocyte meiotic maturation	10
PAK1 and PAK2 in cell metabolism regulation	10
The prominence of potential biomarkers in the diagnosis and management of hepatocellular carcinoma: Current scenario and future anticipation	10
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Computational studies to identify the common type‐I and type‐II inhibitors against the CDK8 enzyme	9
Hypoxia‐induced reprogrammed myoblasts enhance the formation of neuromuscular junctions: A pioneer study	9
Network Pharmacology, Molecular Docking, and Molecular Dynamics Study to Explore the Effect of Resveratrol on Type 2 Diabetes	9
Intrinsic factors behind long COVID: IV. Hypothetical roles of the SARS‐CoV‐2 nucleocapsid protein and its liquid–liquid phase separation	9
A Snapshot of Cytokine Dynamics: A Fine Balance Between Health and Disease	9
The role of BAG3 in health and disease: A “Magic BAG of Tricks”	9
Corrigendum	9
Early induction of Hes1 by bone morphogenetic protein 9 plays a regulatory role in osteoblastic differentiation of a mesenchymal stem cell line	9
Recognition of immune reactive proteins as a potential multiepitope vaccine candidate of Taenia solium cysticerci through proteomic approach	9
Continuous genetic monitoring of transient mesenchymal gene activities in distal tubule and collecting duct epithelial cells during renal fibrosis	9
Molecular Mechanisms of Curdlan‐Induced Suppression of NFATc1 Expression in Osteoclasts	9
DON/DRP‐104 as potent serine protease inhibitors implicated in SARS‐CoV‐2 infection: Comparative binding modes with human TMPRSS2 and novel therapeutic approach	9
Revisiting Luteolin Against the Mediators of Human Metastatic Colorectal Carcinoma: A Biomolecular Approach	9
Correction to “The Oncolytic Virus H101 Combined with Gnaq Sirna‐Mediated Knockdown Reduces Uveal Melanoma Cell Viability”	9
Sweroside alleviates hepatic steatosis in part by activating AMPK/mTOR‐mediated autophagy in mice	9
Thymoquinone and quercetin induce enhanced apoptosis in non‐small cell lung cancer in combination through the Bax/Bcl2 cascade	9
Paraoxonase‐2 shRNA‐mediated gene silencing suppresses proliferation and migration, while promotes chemosensitivity in clear cell renal cell carcinoma cell lines	9
In silico analyses of acetylcholinesterase (AChE) and its genetic variants in interaction with the anti‐Alzheimer drug Rivastigmine	9
Endoplasmic reticulum stress in nonalcoholic (metabolic associated) fatty liver disease (NAFLD/MAFLD)	9
Peroxisome Proliferator‐Activated Receptor‐Gamma Activation by an Active Compound in Lythrum anceps (Koehne) Makino	9
miR‐122 and the WNT/β‐catenin pathway inhibit effects of both interleukin‐1β and tumor necrosis factor‐α in articular chondrocytes in vitro	8
ZNF469 is a profibrotic regulator of extracellular matrix in hepatic stellate cells	8
PDE4 inhibitor eliminates breast cancer stem cells via noncanonical activation of mTOR	8
RETRACTION: Effect of Oridonin on Experimental Animal Model of Bronchopulmonary Dysplasia	8
Maintenance of increased bone mass after PTH withdrawal by sequential medicarpin treatment via augmentation of cAMP‐PKA pathway	8
Arginase 1 expression is increased during hepatic stellate cell activation and facilitates collagen synthesis	8
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Transforming Growth Factor‐β Modulates Cancer Stem Cell Traits on CD44 Subpopulations in Hepatocellular Carcinoma	8
Comparison of potential inhibitors and targeting fat mass and obesity‐associated protein causing diabesity through docking and molecular dynamics strategies	8
RETRACTION: MiR‐125a‐3p Suppresses the Growth and Progression of Papillary Thyroid Carcinoma Cell by Targeting MMP11	8
Stability of S‐nitrosothiols and S‐nitrosylated proteins: A struggle for cellular existence!	8
MSI2 expression in adrenocortical carcinoma: Association with unfavorable prognosis and correlation with steroid and immune‐related pathways	8
Targeting the epithelial–mesenchymal transition (EMT) pathway with combination of Wnt inhibitor and chalcone complexes in lung cancer cells	8
Protein acetylation effects on enzyme activity and metabolic pathway fluxes	7
Breaking down barriers: The potential of smarter CAR‐engineered NK cells against solid tumors	7
Erratum	7
On the origin of BAG(3) and its consequences for an expansion of BAG3's role in protein homeostasis	7
Issue Information	7
Retraction	7
Issue Information	7
Issue Information	7
Therapeutic targeting of microtubule affinity‐regulating kinase 4 in cancer and neurodegenerative diseases	7
Network pharmacology and molecular docking analysis on potential molecular targets and mechanism of action of BRAF inhibitors for application in wound healing	7
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Withdrawal	7
Issue Information	7
Endocannabinoids effect on oxidative status of human platelets	7
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Retraction: ‘MicroRNA‐198 Inhibits Proliferation and Induces Apoptosis of Lung Cancer Cells Via Targeting FGFR1’	7
Structure‐based virtual screening and biological evaluation of novel inhibitors of mycobacterium Z‐ring formation	6
An in‐silico investigation of fluoride ions impact on pancreatic lipase	6
Depletion of Tip60/Kat5 affects the hepatic antioxidant system in mice	6
Antimicrobial‐resistant Neisseria gonorrhoeae can be targeted using inhibitors against evolutionary conservedl‐asparaginase	6
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Issue Information	6
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RETRACTION: MiR‐625‐5p/PKM2 Negatively Regulates Melanoma Glycolysis State	6
Dehydrocostus Lactone Ameliorates LPS‐Induced Acute Lung Injury by Inhibiting PFKFB3‐Mediated Glycolysis	6
CMTM6 and CMTM7: New leads for PD‐L1 regulation in breast cancer cells undergoing EMT	6
Thyroid hormone receptor Thra and Thrb knockout differentially affects osteoblast biology and thyroid hormone responsiveness in vitro	6
Androgen receptor activation decreases proliferation in thyroid cancer cells	6
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The role of S477N mutation in the molecular behavior of SARS‐CoV‐2 spike protein: An in‐silico perspective	6
Corrigendum	6
In silico identification of prolyl hydroxylase inhibitor by per‐residue energy decomposition‐based pharmacophore approach	6
Insights into the binding mechanism between α‐TOH and CYP4F2: A homology modeling, molecular docking, and molecular dynamics simulation study	6
Copper regulation disturbance linked to oxidative stress and cell death during Zika virus infection in human astrocytes	6
Mesenchymal stem cells and ovarian cancer: Is there promising news?	6
Issue Information	6
Issue Information	6
Discovery of octahydropyrrolo [3,2‐b] pyridin derivative as a highly selective Type I inhibitor of FGFR3 over VEGFR2 by high‐throughput virtual screening	5
RNA N6‐methyladenosine demethylase FTO inhibits glucocorticoid‐induced osteoblast differentiation and function in bone marrow mesenchymal stem cells	5
Mechanisms of radioresistance and the underlying signaling pathways in colorectal cancer cells	5
Human placenta‐derived mesenchymal stem cell administration protects against acute lung injury in a mouse model	5
Selection of internalizing RNA aptamers into human breast cancer cells derived from primary sites	5
microRNA‐140‐3p modulates invasiveness, motility, and extracellular matrix adhesion of breast cancer cells by targeting syndecan‐4	5
Ceftriaxone induces glial EAAT‐2 promotor region via NF‐kB conformational changes: An interaction analysis using HADDOCK	5
Illuminating the structural basis of human neurokinin 1 receptor (NK1R) antagonism through classical all‐atoms molecular dynamics simulations	5
Violacein negatively modulates the colorectal cancer survival and epithelial–mesenchymal transition	5
A rationally engineered small antimicrobial peptide with potent antibacterial activity	5
Computational profiling of natural compounds as promising inhibitors against the spike proteins of SARS‐CoV‐2 wild‐type and the variants of concern, viral cell‐entry process, and cytokine storm in COV	5
AIP4 regulates adipocyte differentiation by targeting C/EBPα for ubiquitin‐mediated proteasomal degradation	5
Activation of α7 Nicotinic Acetylcholine Receptor Improves Muscle Endurance by Upregulating Orosomucoid Expression and Glycogen Content in Mice	5
The role of heat shock proteins in metastatic colorectal cancer: A review	5
Molecular dynamics simulations corroborate recombinant expression studies carried out on three αIIb β‐propeller mutations reported in Indian Glanzmann thrombasthenia patients	5
TBC1D2B undergoes phase separation and mediates autophagy initiation	5
Imatinib prevents dexamethasone‐induced pancreatic β‐cell apoptosis via decreased TRAIL and DR5	5
The ameliorating effects of mesenchymal stem cells compared to α‐tocopherol on apoptosis and autophagy in streptozotocin‐induced diabetic rats: Implication of PI3K/Akt signaling pathway and entero‐ins	5
Integrative multiomics and in silico analysis revealed the role of ARHGEF1 and its screened antagonist in mild and severe COVID‐19 patients	5
Inhibition of N‐glycosylation by glucosamine hydrochloride inhibits TGF‐β1‐induced LOXL2 secretion	5
Let‑7f‑5p Regulated by Hsa_circ_0000437 Ameliorates Bleomycin‐Induced Skin Fibrosis	5
State‐of‐the‐art in transposable element modulation affected by drugs in malignant prostatic cancer cells	5
Single‐cell RNA analysis of chromodomain‐encoding genes in mesenchymal stromal cells of the mouse dental pulp	5
Contribution of organokines in the development of NAFLD/NASH associated hepatocellular carcinoma	5
Up‐regulation of inflammatory reactions by MPT32, a secreted protein of Mycobacterium tuberculosis in RAW264.7 macrophages	5
Binding mechanism of anacardic acid, carnosol and garcinol with PCAF: A comprehensive study using molecular docking and molecular dynamics simulations and binding free energy analysis	5
Comprehensive bioinformatics analysis reveals kinase activity profiling associated with heart failure	5
MAP3K7 is an innate immune regulatory gene with increased expression in human and murine kidney intercalated cells following uropathogenic Escherichia coli exposure	5
Tyrosine phosphorylation of YAP‐1 in biliary epithelial cells mediates posthepatectomy liver regeneration and is affected by serotonin	5
PPARγ inhibition promotes osteogenic differentiation of bone marrow mesenchymal stem cells and fracture healing	5
An AS‐qPCR‐based method for the detection of Alzheimer's disease‐related SNPs	5
Inositol polyphosphate multikinase modulates free fatty acids‐induced insulin resistance in primary mouse hepatocytes	5
Unveiling the potential of marine compounds as quorum sensing inhibitors targeting Pseudomonas aeruginosa's LasI: A computational study using molecular docking and molecular dynamics	4
Identification of steroidal saponins from Tribulus terrestris and their in silico docking studies	4
Induction of stearoyl‐CoA desaturase confers cell density‐dependent ferroptosis resistance in melanoma	4
Retraction	4
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Hexokinase 2: The preferential target of trehalose‐6‐phosphate over hexokinase 1	4
Retraction	4
Intrinsic Factors Behind the Long‐COVID: V. Immunometabolic Disorders	4
Retraction	4
Optogenetic control of neural differentiation in Opto‐mGluR6 engineered retinal pigment epithelial cell line and mesenchymal stem cells	4
RETRACTION: Kaempferol Increases Apoptosis in Human Acute Promyelocytic Leukemia Cells and Inhibits Multidrug Resistance Genes	4
Molecular dynamics simulation of Toxin‐Antitoxin (TA) system in Acinetobacter baumannii to explore the novel mechanism for inhibition of cell wall biosynthesis: Zeta Toxin as an effective thera	4
RETRACTION: Propofol‐Induced miR‐219‐5p Inhibits Growth and Invasion of Hepatocellular Carcinoma Through Suppression of GPC3‐Mediated Wnt/β‐Catenin Signalling Activation	4
Long noncoding RNA Gas5 induces cell apoptosis and inhibits tumor growth via activating the CHOP‐dependent endoplasmic reticulum stress pathway in human hepatoblastoma HepG2 cells	4
RETRACTION: FV‐429 Induced Apoptosis Through ROS‐Mediated ERK2 Nuclear Translocation and p53 Activation in Gastric Cancer Cells	4
R‐loops mediate transcription‐associated formation of human rDNA secondary constrictions	4
Divergent Biochemical Properties and Disparate Impact of Arrhythmogenic Calmodulin Mutations on Zebrafish Cardiac Function	4
Understanding the impact of missense mutations on the structure and function of the EDA gene in X‐linked hypohidrotic ectodermal dysplasia: A bioinformatics approach	4
Novel mutation in EFEMP1 identified from two Chinese POAG families differentially activated endoplasmic reticulum stress markers and induced glaucoma in mouse	4
Retraction	4
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Reduced insulin signaling and high glucagon in early insulin resistance impaired fast‐fed regulation of renal gluconeogenesis via insulin receptor substrate	4
Retraction	4
Diagnostic and therapeutic potencies of miR‐18a‐5p in mixed‐type gastric adenocarcinoma	4
Retraction	4
Suppression of transient receptor potential melastatin 7 regulates pluripotency, proliferation, and differentiation of mouse embryonic stem cells via mechanistic target of rapamycin‐extracellular sign	4
Recent Insights Into Wnt‐Related tRNA‐Derived Fragments (tRFs) in Human Diseases	4
Iron dysregulation in COVID‐19 and reciprocal evolution of SARS‐CoV‐2: Natura nihil frustra facit	4
Proteasomal Dysfunction in Cancer: Mechanistic Pathways and Targeted Therapies	4
RETRACTION: Posttreatment of Melatonin With CCl4 Better Reduces Fibrogenic and Oxidative Changes in Liver Than Melatonin Co‐treatment	4
What's in the BAGs? Intrinsic disorder angle of the multifunctionality of the members of a family of chaperone regulators	4
Investigating the Involvement of C−X−C Motif Chemokine 5 and P2X7 Purinoceptor in Ectopic Calcification in Mouse Models of Duchenne Muscular Dystrophy	4
HN1 is a novel dedifferentiation factor involved in regulating the cell cycle and microtubules in SH‐SY5Y neuroblastoma cells	4
Broad‐spectrum cytotoxicity to cancer cells of Brevilaterin C from Brevibacillus laterosporus and its specific mechanism on human epidermal cancer cells	4
FKBP51, a multitasker in protein function, pathway activity, and physiology	4
Retraction	4
Structural and Functional Insight Into YefM–YoeB Complex of Toxin–Antitoxin System From Streptococcus pneumoniae	4
Retraction	4
The animal and cell models that uncovered FKBP51 as a regulator of glucocorticoid receptor function	4
Retraction	4
Role of epigenetics in cellular reprogramming; from iPSCs to disease modeling and cell therapy	4
Retraction	4
Grade‐dependent changes in sphingolipid metabolism in clear cell renal cell carcinoma	4
RETRACTION: Downregulation of Fibroblast Growth Factor 5 Inhibits Cell Growth and Invasion of Human Nonsmall‐Cell Lung Cancer Cells	4
Gastric cancer mesenchymal stem cells promote tumor glycolysis and chemoresistance by regulating B7H3 in gastric cancer cells	4
RETRACTION: Trans‐Cleaving Hammerhead Ribozyme in Specific Regions Can Improve Knockdown Efficiency In Vivo	4