Journal of Pharmaceutical and Biomedical Analysis

Papers
(The median citation count of Journal of Pharmaceutical and Biomedical Analysis is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)
ArticleCitations
LC-MS/MS determination of atropine toxicity: Pre-analytical effect of blood collection tube and analytical matrix169
Metabolomic and sphingolipidomic profiling of human hepatoma cells exposed to widely used pharmaceuticals115
Screening licorice for H2 receptor-binding anti-ulcer components using affinity chromatography108
Editorial Board93
LC-MS/MS method development and validation for novel targeted anticancer therapies adagrasib, capmatinib, ensartinib, entrectinib, larotrectinib, lorlatinib, pralsetinib, selpercatinib and sotorasib84
Development and evaluation of a new test kit for determination of immunosuppressants in blood by UHPLC-MS/MS72
Illuminating green fluorescent protein: Characterizing tri-peptide fluorescent chromophore, probing reactivity of cysteines, and unveiling site-directed modifications through mass spectrometry62
GC and HPLC-RID method development and validation for the determination of twelve related substances, including several novel compounds in tetrabenazine62
Electrochemistry/mass spectrometry (EC/MS) for fast generation and identification of novel reactive metabolites of two unsymmetrical bisacridines with anticancer activity59
Enantioseparation and quantitative analysis of three alkaloids in Rhizoma Corydalis by chiral LC-MS/MS51
Polysaccharides from Balanophora harlandii Hook: Isolation, characterization, and anti-inflammation activities51
The chemical profile and seasonal variation of the composition of the phenolic acids in different plant parts of Centaurea sp.47
Study on the intervention effect of Epimedium before and after suet-oil-processed on kidney yang deficiency rats based on intestinal flora and fecal metabolomics46
Use of Raman spectroscopy and PLS for the quantification of critical quality attributes in biopharmaceutical products45
Development of enantioselective high-performance liquid chromatography-tandem mass spectrometry method for the quantitative determination of 3,4-methylenedioxy-methamphetamine (MDMA) and its phase-1 m44
Comprehensive assessments of pharmacokinetics and immunogenicity of farletuzumab ecteribulin, a novel antibody-drug conjugate against tumors expressing folate receptor α, in monkeys44
Editorial Board43
Identification of plasma biomarkers for non-invasive diagnosis of hepatitis B cirrhosis43
Comparative analysis of chemical components in fruits of Chebulae Fructus and its pulp based on chromatographic technology coupled with multivariate chemometric methods42
Editorial Board40
Editorial Board40
A feasible HPTLC method for concurrent quantitation of allopurinol-montelukast co-therapy in plasma and evaluation of their hepatic and renal effects in rats: Analytical, biochemical, and histopatholo39
A preclinical study on online monitoring of exhaled ciprofol concentration by the ultraviolet time-of-flight spectrometer and prediction of anesthesia depth in beagles39
Qualitative and quantitative evaluations of Chuanxiong dispensing granules by using chemical fingerprint in combination with chemometrics methods39
A high-throughput analytical method for multiple DNA targets based on microdroplet PCR coupled with DGGE38
Identification of ADB-5’Br-BINACA in plant material and analytical characterization using GC-MS, LC-QTOF-MS, NMR and ATR-FTIR35
Integrating 16S rDNA sequencing analysis and targeted metabolomics to explore the mechanism of Xiexin Tang in treating atherosclerosis mice induced by high-fat diet35
Guilty by dissociation: Part C: Enantiomeric separation of diphenidine-derived new psychoactive substances (NPS) by polar organic chiral high performance liquid chromatography (HPLC) on polysaccharide35
Combined untargeted metabolomics and network pharmacology approaches to reveal the therapeutic role of withanolide B in psoriasis34
Separation and identification of a complex flurbiprofen-polyethylene glycol mono- and diester mixture via a hyphenated HPLC-DAD-HRMS/SPE NMR system34
Chromatographic analysis and pKa evaluation of active pharmaceutical ingredients in anti-metastatic breast cancer: Green vs. conventional RPLC33
Liuwei Dihuang Formula ameliorates glycolipid metabolism in type 2 diabetic rats through an integrated analysis of gut microbiota and bile acids33
Integrated UHPLC-MS untargeted metabolomics and gut microbe metabolism pathway-targeted metabolomics to reveal the prevention mechanism of Gushudan on kidney-yang-deficiency-syndrome rats33
Metabolomics-based investigation of the chemical composition changes in Mongolian medicinal plant Euphorbia pekinensis before and after processing with Chebulae Fructus33
Development and validation of derivatization-based LC-MS/MS method for quantification of short-chain fatty acids in human, rat, and mouse plasma32
Emerging analytical techniques for pharmaceutical quality control: Where are we in 2022?31
Analysis of growth hormone releasing hormone and its analogs in urine using nano liquid chromatography coupled with quadrupole/orbitrap mass spectrometry31
Equine in vivo metabolite profiling of the selective androgen receptor modulator LGD-3303 for doping control31
Determination of 13 potential anti-obesity agents in hair by dispersive liquid-liquid microextraction-assisted UHPLC-MS/MS31
Automated ELISA for potency measurements of therapeutic antibodies and antibody fragments30
Editorial Board30
Qualitative and quantitative analysis of major components in Abelmoschus manihot flowers treated with different drying methods using UHPLC Q-exactive MS and HPLC-PDA30
First-in-human study to assess the safety, tolerability, and pharmacokinetics of intravenous SHPL-49 following single- and multiple-ascending-dose administration in healthy adults29
Integrated metabolomics and gut microbiota analysis to explore potential mechanism of Qi-Huo-Yi-Fei formula against chronic obstructive pulmonary disease29
The discovery of pharmacodynamic material basis and mechanism of Shuganning injection in treating damp-heat jaundice syndrome: Combining metabolomics and serum pharmacochemistry29
Proteomic analysis reveals that Polygonatum cyrtonema Hua polysaccharide ameliorates mice muscle atrophy in chemotherapy-induced cachexia29
Precolumn derivatization LC-MS/MS method to simultaneous quantitation of 10 monosaccharides in rat plasma29
Advanced design of chemically modified electrodes for the electrochemical analysis of uric acid and xanthine29
Amanitin determination in bile samples by UHPLC-MS: LR-MS and HR-MS analytical performance28
Development of salting-out extraction methodology for the determination of piroxicam from polymeric based nanocarriers and biological samples28
Recent progress in the graphene-based biosensing approaches for the detection of Alzheimer's biomarkers28
Determination of famprofazone, amphetamine and methamphetamine in liver samples using enzymatic cell dispersion and SPE-LC-ESI-MS28
Discovery of a predictive model for anlotinib-induced hand-foot syndrome based on metabolomics28
Recent advances in wearable medical diagnostic sensors and new therapeutic dosage forms for fever in children28
A comprehensive strategy for the identification of biologics by liquid-chromatography–mass spectrometry for release testing in a regulated environment28
Integrated cartilage metabolomics and proteomics analysis reveals the therapeutic effect of Wenjing Tongluo Decoction on Knee osteoarthritis rats27
A simplified non-reduced peptide mapping method with faster and efficient enzymatic digestion for characterization of native disulfide bonds in monoclonal and bispecific antibodies27
Determination of lithium concentration in capillary blood using volumetric dried blood spots27
Characterization of the tautomeric equilibrium of molnupiravir, an antiviral for the treatment of COVID-1927
An efficient approach to probe bioactive components of herbal patches by 2D-carbon microfiber fractionation and multi-chamber membrane separation electrophoresis: Spatholobus suberectus Dunn as a case27
New insights into the chemistry and anticancer activity of Ophiocordyceps xuefengensis27
Bifunctional electrochemical biosensor based on PB-MXene films for the real-time analysis and detection of living cancer cells27
The importance of method validation in herbal drug research26
Exploring the gut microbiota mediated biotransformation of Senecio scandens Buch.-Ham.: Insights from metabolite spectrum with UHPLC-Q-Orbitrap HRMS and bioinformatics analysis of gut microbiota metab26
A sensitive UPLC-MS/MS method for the simultaneous determination of the metabolites in the tryptophan pathway in rat plasma26
Development of organic three-phase laminar flow microfluidic chip for extraction of ginsenosides from Panax ginseng26
Metabolomic and biochemical changes in the plasma and liver of toxic milk mice model of Wilson disease26
Rapid detection of rocuronium based on host/guest complex between a pyrene derivative and sugammadex26
Xi Huang Pill exerts anti-triple-negative breast cancer effects by modulating gut microbiota, regulating glycerophospholipid metabolism, and promoting autophagy homeostasis25
An evaluation of qH NMR: A complementary approach to GC-FID for quantification of Thymol and trans-Anethole in essential oils and supplements25
Development and evaluation of a HILIC-MS method for the determination of amino acid and non-amino acid impurities in histidine25
Qualitative and quantitative analysis of the component variations of Raphani Semen during the stir-frying process and elucidation of transformation pathways of multiple components25
Development and validation of a label-free HPLC-CAD method to determine total sialic acid in therapeutic proteins25
Stability of the antibiotic ceftaroline fosamil with focus on degradation products and decomposition pathways – Integrative analysis by LC-DAD, ESI-QTOF and in silico prediction25
Optimization of bronchoalveolar lavage fluid volume for untargeted lipidomic method and application in influenza A virus infection24
HPLC-based kinetics assay for monitoring prolidase activity24
Molecular imprinting-based sensors: Lab-on-chip integration and biomedical applications24
Development of a reliable cell-based reporter gene assay to measure the bioactivity of anti-HER2 therapeutic antibodies24
Pharmacokinetics of two triterpenoid saponins and three flavonoids in Astragalus membranaceus leaves by UHPLC-MS/MS24
A magnetic ionic liquid based vortex-assisted dispersive liquid-liquid microextraction coupled with back-extraction for the enrichment of fluoroquinolone antibiotics24
Impact and mitigation of near infrared absorption in quantitative Transmission Raman Spectroscopy24
Discovering the metabolic pathway of liver disease by breath mass spectrometry combined with machine learning24
The effective compounds and mechanisms of Cang-Fu-Dao-Tan Formula in treating polycystic ovary syndrome based on UPLC/Q-TOF-MS/MS, network pharmacology and molecular experiments24
Metabolomics research on treatment of primary liver cancer with Cortex Juglandis Mandshuricae on LC-MS/MS technology24
Development and validation of a simple and affordable LC-UV method for identification and assay of selected antimicrobial medicines23
Biological analysis of constituents in Spatholobi Caulis by UFLC-MS/MS: Enhanced quantification and application to permeability properties study in Caco-2 cell monolayer model23
Combination of histological and metabolomic assessments to evaluate the potential pharmacological efficacy of saikosaponin D23
Editorial Board23
Variable temperature-nuclear magnetic resonance experiment and high-resolution MS/MSn measurement of hydroxycarbodenafil, and its PDE5 inhibitory activity23
Determination of five mTOR inhibitors in human plasma for hepatocellular carcinoma treatment using QuEChERS-UHPLC-MS/MS23
Too much or too little caffeine? Determination of content in thermogenic capsules by quantitative 1H nuclear magnetic resonance (qNMR)23
Joint proteomic and metabolomic analysis reveals renal metabolic remodeling of chronic heart failure mice23
Biotransformation and brain distribution of the anti-COVID-19 drug molnupiravir and herb-drug pharmacokinetic interactions between the herbal extract Scutellaria formula-NRICM10123
Omics analysis unveils changes in the metabolome and lipidome of Caenorhabditis elegans upon polydopamine exposure23
Simultaneous and rapid analysis of chiral Danshensu and its ester derivatives by supercritical fluid chromatography22
Editorial Board22
Lipidomic profiling of amniotic fluid reveals aberrant fetal lung development and fetal growth disrupted by lipid disorders during gestational asthma22
Development of a derivatization RP-HPLC method for determination of sulfuryl chloride in chlorosulfonic acid for gefapixant citrate manufacture22
Effects of compound Anoectochilus roxburghii (Wall.) Lindl. oral liquid on relative metabolic enzymes and various biochemical indices in Wistar rats with isoniazid-induced liver injury21
Tracking the physicochemical stability of teduglutide (Revestive®) clinical solutions over time in different storage containers21
Chemometric assisted natural DES based VA-DLLME-LC-MS/MS method for the quantitative determination of Garcinol in biofluids/tissues: A practical application to pharmacokinetics and biodistribution stu21
Study on the active ingredients and mechanism of Huyang Yangkun Formula for treating premature ovarian insufficiency via chemical profiling, network pharmacology, and experimental validation21
An NMR-based metabolomics strategy for adulteration detection of natural resins: Application to Chios mastic gum21
Testing for clomiphene in keratinous matrices using LC–MS/MS in doping purpose: Is a single intake of clomiphene detectable in hair and nail clippings?21
Simultaneous determination of ceftazidime and pyridine in human plasma by LC-UV21
A comprehensive method for quality evaluation of Tibetan medicine Synotis solidaginea by integrating UHPLC-Q-Orbitrap MS chemical profiling and UHPLC-DAD multi-components quantification21
Metabolomics uncovers Rubus idaeus-mediated recovery of energy and arginine metabolism in liver injury21
Qualitative and quantitative comparison of different commercially available 1–84 parathyroid hormone proteins to the WHO international standard 95/646 using orthogonal methods21
Effective enrichment and separation of three flavonoids from Ohwia caudata (Thunberg) H. Ohashi using magnetic layered double hydroxide/ZIF-8 composites and pCEC21
Whole-cell aptamer-based techniques for rapid bacterial detection: Alternatives to traditional methods20
Multi-omics analysis of kidney, bone and bone marrow explored potential mechanisms of Erzhi Wan against osteoporosis with kidney-Yin deficiency20
Jingning formula alleviates ADHD by restoring gut microbiota dysbiosis and tryptophan metabolic dysfunction20
Feasibility of using elemental analysis measured by inductively coupled Plasma-Optical emission spectroscopy for the discrimination of red lipsticks by brand and shade20
Identification of potential drug targets for four site-specific cancers by integrating human plasma proteome with genome20
HPLC methods for studying pharmacokinetics of tivozanib and in vitro metabolic interaction with dexamethasone in rat20
Comprehensive evaluation and screening of phytochemical compounds and their hypolipidemic activities of lotus leaf based on HPLC-Q-TOF-MS and spectral-effect analysis20
HPLC-UV method validation for quantification of β-carotene in the development of sustained release supplement formulation containing solid dispersion-floating gel in situ20
UPLC-Q-Exactive/MS–based metabonomics revealed protective effect of Citri Sarcodactylis and its product on gastrointestinal motility disorders20
Plasma metabolomics identifies S-adenosylmethionine as a biomarker and potential therapeutic target for vascular aging in older adult males20
A strategy takes “Yiqing” tablets as an example to carry out simpler multi-component quantification and use fingerprint technology for comprehensive quality consistency evaluation20
Biopharmaceutical assessment of naloxone permeation through human respiratory epithelial tissues: A chromatographic-mass spectrometric approach with cloud based aerosol dosing and delivery20
Analysis of genotoxic N-nitrosamines in active pharmaceutical ingredients and market authorized products in low abundance by means of liquid chromatography – tandem mass spectrometry20
A simple and sensitive differential digestion method to analyze adeno-associated virus residual host cell proteins by LC-MS20
Editorial Board19
Development of a rapid and sensitive LC-MS/MS assay for the quantification of commonly abused drugs in Asia in a micro-segment of a single hair using microwave-assisted extraction and dansyl chloride d19
Chip-based digital PCR as a direct quantification method for residual DNA in mRNA drugs19
Development and validation of a liquid chromatographic-tandem mass spectrometric assay for the quantification of cabotegravir and rilpivirine from dried blood spots19
A combination of amino-functionalized fibrous silica (KCC-1-NH2)/effectively and efficiently oxidized graphene oxide (EEGO) nanocomposite for dispersive solid-phase extraction, pre-concentration and f19
UPLC-Q-TOF/MS-based study on chemical composition, in vivo metabolites, and tissue distribution of ethanol extract of Ganoderma lucidum19
Study on the white frost formation mechanism during storage of Phyllanthus emblica Linn. fruit based on component analysis and spatial metabolomics19
Mechanism-based perspective on metal ion-induced signal instability and development of a robust LC-MS/MS method for trace quantification of hetrombopag in plasma19
THC and THC-COOH hair concentrations: Influence of age, gender, consumption habits, cosmetics treatment, and hair features19
Immunomodulatory effect of Liangyi paste on the gut microbiota of mice19
Revealing metabolic alterations in brucellosis patients by targeted metabolomics19
Fluorescent "turn-on" aptamer sensor for sensitive and reliable detection of Golgi glycoprotein 73 based on nitrogen-doped graphene quantum dots and molybdenum disulfide nanosheets19
Rapid identification and quantification of Pseudostellaria heterophylla with its adulterants by HPLC-CAD fingerprint combined with improved quantitative analysis of multi-components by single marker (19
Distinct chemical degradation pathways of AAV1 and AAV8 under thermal stress conditions revealed by analytical anion exchange chromatography and LC-MS-based peptide mapping19
Characterization and determination of the major constituents in whitening-potential aqueous extract of Nardostachys jatamansi DC18
Discovery of bioactive compounds targeting endothelin A receptor and angiotensin II type 1 receptor in Gegen Qinlian decoction by co-immobilized receptor chromatography18
Deciphering the metabolic profile and anti-colorectal cancer mechanism of Capilliposide A using ultra performance liquid chromatography mass spectrometry combined with non-targeted metabolomics studie18
Application of LEDA algorithm for the recognition of P-glycoprotein and Carbonic Anhydrase hybrid inhibitors and evaluation of their plasma stability by HPLC-MS/MS analysis18
Liquid chromatography-tandem mass spectrometry analysis of delamanid and its metabolite in human cerebrospinal fluid using protein precipitation and on-line solid-phase extraction18
Quantification of endogenous Angiotensin 1-10, 1-9, 1-8, 1-7, and 1-5 in human plasma using micro-UHPLC-MS/MS: Outlining the importance of the pre-analytics for reliable results18
Simultaneous analysis of four endocannabinoids and endocannabinoid congeners together with delta-9 tetrahydrocannabinol and related metabolites in dried blood spots18
Monitoring of alcohol-based hand rubs in SARS-CoV-2 prevention by HS-GC/MS and electrochemical biosensor: A survey of commercial samples18
Molecular quantification for differentiation of fresh and dried Jinqian Baihua She18
Degradation kinetics and characterization of major degradants of binimetinib employing liquid chromatography-high resolution mass spectrometry18
Antibody-free quantification of serum infliximab using LC-MS/MS18
Editorial Board18
Biotransformation of 5-methoxy-N-isopropyl-N-methyltryptamine by zebrafish and human liver microsome with high-resolution mass spectrometry18
Metabolic stability assessment and metabolite profiling of gunagratinib, a novel FGFR inhibitor, in rat, monkey and human liver microsomes by an integrated analysis method based on HPLC-MS/MS and HPLC18
The screened compounds from Ligustri Lucidi Fructus using the immobilized calcium sensing receptor column exhibit osteogenic activity in vitro18
A universal method for profiling and characterization of oligosaccharides in traditional Chinese medicines18
Development and optimization of a high-throughput LC-MS/MS method for the simultaneous determination of Exatecan and its Cathepsin B-sensitive prodrug, and ARV-825 in rat plasma: Application to pharma18
Dimension-enhanced liquid chromatography/mass spectrometry approaches better decipher the difference in chemical compositions of Erzhi formula and Jiawei Erzhi formula17
Characterization of low-level D-amino acid isomeric impurities of Semaglutide using liquid chromatography-high resolution tandem mass spectrometry17
Reverse traceability analysis of estrogenic active ingredients in Cuscutae semen based on intestinal and hepatic metabolism17
Comparisons of pharmacokinetics and tissue distribution of six major bioactive components of the herbal pair Alpinia officinarum-Cyperus rotundus in normal and primary dysmenorrhea rats17
Corrigendum to “Dissecting the antitumor effects of Scutellaria barbata: Initial insights into the metabolism of scutellarin and luteolin by gut microbiota” [J. Pharm. Biomed. Anal. 248 (2024) 116325]17
Platform headspace gas chromatography method for high-throughput determination of residual solvents in pharmaceutical materials17
Determination of metabolic markers for lipid metabolism disorders and liver injury recovery via PXR/FXR-CYP7A1 regulation by Folium Ginkgo17
Identifying biomarkers for nasopharyngeal carcinoma diagnosis and chemoradiotherapy response using serum endogenous small molecules profiling17
Development and validation of an analytical method for the simultaneous quantitation of posaconazole Form I and Form-S in oral suspensions17
UPLC-ESI-Q-TOF-MS/MS based metabolomics investigation on chemical constituent consistency of Zhenwu Decoction before and after compatibility17
Determination of ten antipsychotics in blood, hair and nails: Validation of a LC–MS/MS method and forensic application of keratinized matrix analysis17
A strategy integrated DNA barcoding with metabolomics for screening distinguishable combinatorial chemical quality marker between Pheretima aspergillum and Pheretima vulgaris Chen17
The protective effect of asperuloside on liver injury: Insights from metabolomics and the mTOR-mediated autophagy perspective17
Bringing an immuno-PCR-based pharmacodynamic biomarker assay for reduced human IL-33 in serum, plasma, and aqueous humor into the clinic17
Evaluation of 4 quantification methods for monitoring 16 antibiotics and 1 beta-lactamase inhibitor in human serum by high-performance liquid chromatography with tandem mass spectrometry detection17
The quality of drugs and drug products – Always guaranteed?17
Application of microdialysis combined with lipidomics to analyze fatty acid metabolic changes in the disease process of rheumatoid arthritis17
Confined CHA-HCR system for sensitive and specific detection of ANXA2 mRNA in adenomyosis tissues17
Simultaneous quantification of seven B vitamins in human faeces by stable isotope label-based high-performance liquid chromatography-tandem mass spectrometry17
Multidimensional isotope analysis of carbon, hydrogen, and oxygen as a tool for traceability of lactose in drug products16
A dual-fingerprint approach based on parameter systems for comprehensive quality evaluation of Belamcandae Rhizoma16
Application of electron paramagnetic resonance spectroscopy to examine free radicals formed in indapamide and torasemide storage under UV irradiation and at the higher temperatures which appear under 16
Dual-mode, signal-amplified DNA biosensor for label-free, reliable assay of gestational diabetes mellitus-related miRNA (miR-135a)16
Investigation of excipients impact on polysorbate 80 degradation in biopharmaceutical formulation buffers16
Applying cross-correlation for thermal stability analysis of protein therapeutics16
Rapid screening of hepatotoxic components in Uncariae Ramulus Cum Uncis based on “component-target-pathway” network16
A serum metabolomics study based on LC-MS: Chemosensitization effects of Rauvolfia vomitoria Afzel. combined with 5- fluorouracil on colorectal cancer mice16
LC-PDA-QTof-MS characterization of the stress degradation products of Zanubrutinib: A novel BTK inhibitor16
An efficient and reliable determination of hyaluronidase supports revision of the United States Pharmacopeia USP46-NF41 monograph – Hyaluronidase for injection16
Editorial Board16
A validated method for detection of cannflavins in hemp extracts16
Development of an hollow fiber solid phase microextraction method for the analysis of unbound fraction of imatinib and N-desmethyl imatinib in human plasma16
Rapid detection and quantification of falsified Viagra using cloud-based portable NIR technology and machine learning16
Quality evaluation of Citri Reticulatae Pericarpium by supercritical fluid chromatography with chemical pattern recognition16
Development and validation of an ADRβ1-SNAP-tag/CMC model for screening ADRβ1 antagonists: Application to nebivolol and its byproducts16
A multi-target QSRR approach to model retention times of small molecules in RPLC16
Sigma receptor and aquaporin modulators: chiral resolution, configurational assignment, and preliminary biological profile of RC752 enantiomers16
Editorial Board16
UHPLC-MS/MS-based analysis of 17 nitazenes in human hair for practical forensic casework with simultaneous separation of 6 groups of isomers16
Integration of serum pharmacochemistry, chromatographic fingerprint, and network pharmacology to identify chemical markers for quality makers of Di Huang Yin Zi16
Investigation of stereochemical stability of 2-, 3- and 4-chloromethcathinones in various biological matrixes16
Neurotransmitter analysis using liquid chromatography-electrochemical detection in the 21st century: Critical review from an analytical chemistry perspective15
Orthogonal chemical-biological profiling of bioactive components from Olea europaea L. fruits for mitigating hypoxia-induced cellular injury15
N-Nitrosodimethylamine formation in metformin hydrochloride sustained-release tablets: Effects of metformin and hypromellose used in drug product formulation15
A multistep approach for exploring quality markers of Shengjiang Xiexin decoction by integrating plasma pharmacochemistry-pharmacokinetics-pharmacology15
Rapid detection of phenytoin sodium by partial-least squares and linear regression models combined with surface-enhanced Raman spectroscopy15
Validation of a fast and sensitive UPLC-MS/MS quantitative method for N-acyl taurine analysis in biological samples15
Stability of antipsychotic biomarkers for wastewater-based epidemiology15
Monolithic and hierarchically porous biochar/cellulose aerogel as adsorbent for microextraction in packed syringe towards trace sulfonamides in water samples prior to UPLC-MS/MS15
A sensitive UPLC-MS/MS method for simultaneous quantification of one-carbon metabolites & co-factors in human plasma15
Addressing common challenges of biotherapeutic protein peptide mapping using recombinant trypsin15
A dual-target SPR screening system for simultaneous ligand discovery of SARS-CoV-2 spike protein and its receptor ACE2 from Chinese herbs15
Adaptive wavenumber selection framework for medicine authenticity assessment15
Guilty by dissociation: Part B: evaluation of Supercritical Fluid Chromatography (SFC-UV) for the analysis of regioisomeric diphenidine-derived Novel Psychoactive Substances (NPS)15
Development and validation of a fast UPLC-MS/MS screening method for the detection of 68 psychoactive drugs and metabolites in whole blood and application to post-mortem cases15
Non-targeted metabolite characterization in microsomal assay using liquid chromatography coupled to high-resolution mass spectrometry: Application to carisoprodol15
Identification and characterization of forced degradation products of sertraline hydrochloride using UPLC, ultra-high-performance liquid Chromatography-Quadrupole-Time of flight mass spectrometry (UHP15
Alterations in serum metabolic profiles of early-stage hepatocellular carcinoma patients after radiofrequency ablation therapy15
Quantitative study on a simple electrochemical dsDNA-pregabalin biosensor; multi-spectroscopic, molecular docking and modelling studies15
Targeted characterization and guided isolation of chemical components in Scrophulariae Radix based on LC-MS15
Hyaluronic acid skin penetration evaluated by tape stripping using ELISA kit assay15
A comprehensive study of the effect of elevated temperature on the extractability and rate of exaggerated and exhaustive extractions of medical devices15
HPLC-fluorescence detection for stability of harringtonine, and identification of degradation products by UPLC-Q-TOF-MS15
Comparison of capillary electrophoresis-based methods for the analytical characterization of purity and stability of in vitro transcribed mRNA15
Holistic quality evaluation of Callicarpae Formosanae Folium by multi-chromatography-based qualitative and quantitative analysis of polysaccharides and small molecules15
Development of UPLC–MS/MS method for studying the pharmacokinetic interactions of fuzuloparib with curcumin in rats15
Definition of multivariate acceptance limits (guard-bands) applied to pharmaceutical equivalence assessment15
Phytochemical profiling of Symplocos tanakana Nakai and S. sawafutagi Nagam. leaf and identification of their antioxidant and anti-diabetic potential15
Accurate determination for lipidomics based on LC-tandem-MS parameters modeling, prediction, and database: Monitoring the progression of hepatocellular carcinoma15
Exploration of the intestinal flora to reveal the important contribution of Radix Astragali to Huangqi Jianzhong Tang in treating chronic atrophic gastritis rats15
Deciphering the molecular mechanism of Bu Yang Huan Wu Decoction in interference with diabetic pulmonary fibrosis via regulating oxidative stress and lipid metabolism disorder15
Salting-out assisted liquid-liquid extraction (SALLE): Principle, optimization, and applications in blood sample analysis15
Analysis of quality differences between Scutellaria baicalensis Georgi and Scutellaria rehderiana Diels based on phytochemistry and bioactivity evaluation15
Characterization of in-vivo human metabolites of the oral nucleoside anti-COVID-19 drug VV116 using UHPLC-Orbitrap-MS15
Fourier transform infrared spectroscopy, high-performance liquid chromatography with diode array detection, and gas chromatography-mass spectrometry fingerprints combined with chemometrics for compreh15
Simultaneous quantification of nirmatrelvir/ritonavir in human serum by LC–HRMS14
Pseudotargeted metabolomics profiles potential damage-associated molecular patterns as machine learning predictors for acute pancreatitis14
Simultaneous relative UV response determination of known liquid drug product degradants by NMR spectroscopy14
Evaluation of the effect of CYP2D6*3, *4,*10, and *17 polymorphisms on the pharmacokinetic of tamoxifen and its metabolites in patients with hormone-positive breast cancer14
An investigation of the plasma and urinary metabolite profiles of the hepatotoxin methapyrilene in the male Wistar rat14
Comparisons of the bioavailability of icariin, icariside II, and epimedin C in rats after oral administration of total flavonoids of Epimedium brevicornu Maxim. and its three formulations14
Targeted and non-targeted metabolomics uncovering the effects of Er-Miao-Wan formula on rats with hyperuricemia14
Evaluation of MALDI-TOF MS, sequencing of D2 LSU rRNA and internal transcribed spacer regions (ITS) for the identification of filamentous fungi isolated from a pharmaceutical facility14
Identifying the active ingredients of carbonized Typhae Pollen by spectrum-effect relationship combined with MBPLS, PLS, and SVM algorithms14
Physicochemical and structural analysis of N-phenylacetyl-L-prolylglycine ethyl ester (Noopept) – An active pharmaceutical ingredient with nootropic activity14
LC-MS/MS quantitation of non-psychotropic cannabinoid cannabidiol in aqueous humor14
A novel automated multi-cycle magnetic solid-phase extraction coupled to LC-MS/MS to study the disorders of six functional B vitamins in patients with gastroenterology and hyperhomocysteinemia14
Evaluation of quality consistency of herbal preparations using five-wavelength fusion HPLC fingerprint combined with ATR-FT-IR spectral quantized fingerprint: Belamcandae rhizoma antiviral injection a14
Cu@ZIF-8 coupled to UPLC-UV for rapid and sensitive analysis of emodin and rhein in urine samples14
Development and validation of LC-MS/MS methods for the pharmacokinetic assessment of the PROTACs bavdeglutamide (ARV-110) and vepdegestrant (ARV-471)14
Photodegradation of indomethacin and naproxen contained within commercial products for skin – RAP14
Integrating proteomics, metabolomics, and network pharmacology to investigate the mechanism of Cordyceps sinensis in the treatment of COPD rats14
Development and validation of a GC method for a key nemtabrutinib intermediate: Implementation of an in-situ free base sample preparation protocol14
Leveraging ToF-SIMS imaging to investigate tenofovir disoproxil fumarate degradation at excipient interfaces in oral compressed tablets14
A fast and efficient method for screening and evaluation of hypoglycemic ingredients of Traditional Chinese Medicine acting on PTP1B by capillary electrophoresis14
Chemical profiling of Zhi-Ke-Bao pills and its potential mechanism against cough by ultra-high performance liquid chromatography coupled to quadrupole time-of-flight mass spectrometry and network phar14
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