Journal of Pharmaceutical and Biomedical Analysis

Article	Citations
Chiral high-performance liquid chromatography analysis of mono-, di-, and triacylglycerols with amylose- and cellulose-phenylcarbamate-based stationary phases	279
A reliable LC-MS/MS method for the quantification of natural amino acids in human plasma and its application in clinic	139
Metabolomic and biochemical changes in the plasma and liver of toxic milk mice model of Wilson disease	100
Polysaccharides from Balanophora harlandii Hook: Isolation, characterization, and anti-inflammation activities	82
Determination of 13 potential anti-obesity agents in hair by dispersive liquid-liquid microextraction-assisted UHPLC-MS/MS	62
New piperazine and morpholine derivatives: Mass spectrometry characterization and evaluation of their antimicrobial activity	58
Editorial Board	57
Chromatographic analysis and pKa evaluation of active pharmaceutical ingredients in anti-metastatic breast cancer: Green vs. conventional RPLC	52
Extrahepatic in vitro metabolism of peptides; comparison of human kidney and intestinal S9 fraction, human plasma and proximal tubule cells, using cyclosporine A, leuprorelin, and cetrorelix as model	51
LC-MS/MS studies for identification and characterization of new forced degradation products of dabrafenib and establishment of their degradation pathway	45
Chemical profiling of Houttuynia cordata Thunb. by UPLC-Q-TOF-MS and analysis of its antioxidant activity in C2C12 cells	44
Quantification of nine psychotropic drugs in postmortem dried blood spot samples by liquid chromatography–tandem mass spectrometry for simple toxicological analysis	42
Synthesis and standardization of an impurity of acetaminophen, development and validation of liquid chromatographic method	40
Simultaneous determination of praziquantel, fipronil, eprinomectin, (S)-methoprene, their key related substances and butylated hydroxytoluene (BHT) in a topical veterinary drug product by a single sta	39
Comprehensive evaluation of the mechanism of Banxia Baizhu Tianma Decoction in ameliorating posterior circulation ischemia vertigo based on integrating fecal short-chain fatty acids and 16S rRNA seque	38
Amanitin determination in bile samples by UHPLC-MS: LR-MS and HR-MS analytical performance	38
Comparison of whole-blood sirolimus concentrations measured by EMIT-based Siemens Viva-ProE® System and LC-MS/MS in Chinese transplant patients	37
A study on cholesterol-cholesteryl ester metabolic homeostasis and drug intervention in hyperlipidemic hamsters using UHPLC-MS/MS	37
Nano-zirconium-silicate solid-phase extraction method for the rapid quantification of pyrrolizidine alkaloids from plant extracts by UHPLC-QTOF-MS	35
Determination of related substances in egg yolk lecithin by HPLC-CAD and characterization of its profiling by HPLC-Q-TOF-MS	35
Quantitation of total antibody (tAb) from antibody drug conjugate (ADC) PYX-201 in rat and monkey plasma using an enzyme-linked immunosorbent assay (ELISA) and its application in preclinical studies	35
In vitro characterization of S-23 metabolites produced by human liver microsomes, and subsequent application to urine after a controlled oral administration	34
N-glycosylation structure – function characterization of omalizumab, an anti-asthma biotherapeutic product	34
Anti-heart failure mechanism of saponin extract of black ginseng based on metabolomics	33
Chiral LC-MS/MS method for the simultaneous determination of (R,S)-ketamine, (R,S)-norketamine, and (2R,6R;2S,6S)-hydroxynorketamine in mouse plasma and brain	33

Antioxidant compounds of Kielmeyera coriacea Mart. with α-amylase, lipase and advanced glycation end-product inhibitory activities	33
A fit-for-purpose LC-MS/MS method for the analysis of selected Streptococcal quorum sensing peptides in human saliva	33
Application of novel metal organic framework-deep eutectic solvent/molecularly imprinted polymer multiple monolithic fiber for solid phase microextraction of amphetamines and modafinil in unauthorized	32
Ultra-high performance supercritical fluid chromatography method for separation and quantitation of saikosaponins in herbal medicine	32
Development of enantioselective high-performance liquid chromatography-tandem mass spectrometry method for the quantitative determination of 3,4-methylenedioxy-methamphetamine (MDMA) and its phase-1 m	31
Mass spectrometry imaging-based metabolomics highlights spatial metabolic alterations in three types of liver injuries	31
A novel and water-soluble material for coronavirus inactivation from oseltamivir in the cavity of methyl and sulfated-β-cyclodextrins through inclusion complexation	31
Characterization of phenolics and discovery of α-glucosidase inhibitors in Artemisia argyi leaves based on ultra-performance liquid chromatography-tandem mass spectrometry and relevance analysis	31
Combined untargeted metabolomics and network pharmacology approaches to reveal the therapeutic role of withanolide B in psoriasis	30
Microdialysis as a sampling tool for the chemotherapeutic agent Doxorubicin	30
Effects of sulfur-fumigated ginseng on the global quality of Si-Jun-Zi decoction, a traditional ginseng-containing multi-herb prescription, evaluated by metabolomics and glycomics strategies	30
Development and evaluation of a new test kit for determination of immunosuppressants in blood by UHPLC-MS/MS	30
Quality evaluation of Qiangli Tianma Duzhong (QLTMDZ) employing UHPLC-MS: A multivariate statistical analysis across multiple dosage forms and manufacturers	29
Matrix-assisted laser desorption/ionization mass spectrometric imaging the spatial distribution of biodegradable vascular stents using a self-made semi-quantitative target plate	28
The nitrosamine contamination of drugs, part 3: Quantification of 4-Methyl-1-nitrosopiperazine in rifampicin capsules by LC-MS/HRMS	28
Kinetic and mechanism study of the spontaneous, solvent- and base-catalyzed degradation of the precursor of the β-nitro alcohol metaraminol by combining HPLC/electronic circular dichroism/theoretical	28
HILIC-UV determination of lysine and chloride counterions in active pharmaceutical ingredients	28
Editorial Board	28
Development and validation of an HPLC-MS/MS method for the quantification of the anti-leishmanial drug miltefosine in human skin tissue	28
Development and validation of bioanalytical assays for the quantification of 9MW2821, a nectin-4-targeting antibody–drug conjugate	28
Mass spectrum oriented metabolomics for evaluating the efficacy and discovering the metabolic mechanism of Naoling Pian for insomnia	27
Qualitative and quantitative evaluations of Chuanxiong dispensing granules by using chemical fingerprint in combination with chemometrics methods	27
Chemical profiles, differentiation, and quality evaluation of Radix et Rhizoma Thalictri Foliolosi based on LC-MS	27
Single-type reporter multiplexing with A single droplet through bead-based digital microfluidics	27
Multinuclear NMR screening of pharmaceuticals using standardization by 2H integral of a deuterated solvent	27
Quantitative Quadrupolar NMR (qQNMR) via nitrogen-14 for the accurate control of L-carnitine in food supplements	26
Development, methodological evaluation and application of a cell-based TRF assay for analysis of ADCC activity	26
2-μm fused-core column ultra-high-performance liquid chromatography/tandem mass spectrometric determination of donepezil in human plasma: Application to a bioequivalence study	26
Development and validation of an LC-MS/MS assay for the quantification of cintirorgon (LYC-55716) in mouse plasma and tissue homogenates	26
Updating the European Pharmacopoeia impurity profiling method for cetirizine and suggesting alternative column, using design space comparison	26
Disposable nanosensor for the electrochemical determination of the interaction between DNA, and a mycotoxin, patulin	26
l-Asparaginase and HCP quantification by SWATH LC-MS/MS for new and improved purification step in Erwinia chrysanthemi l-asparaginase manufacture	26
New stochastic devices for simultaneous analysis of mismatch repair proteins and KRAS in biological samples	26
Correlation analysis of physicochemical properties with anti-inflammatory activity of Andrographis paniculata (Burm.f.) Nees based on HPLC-DAD, colorimeter and multivariate statistics: A comprehensive	26
Mariani wine: What's really in it? Analysis of the most popular tonic drink of the 19th century after 100 years of storage	26
Green, rapid and simultaneous determination of ‘alternative preservatives’ in cosmetic formulations by gas chromatography-mass spectrometry	25
Development of organic three-phase laminar flow microfluidic chip for extraction of ginsenosides from Panax ginseng	25
Detection and differentiation of active and inactive isoforms of coagulation factors II, VII, IX, and X in prothrombin complex concentrate by mass spectrometry	25
Serum and urine metabolomics study revealed the amelioration of Gynura bicolor extract on high fat diet-fed and streptozotocin-induced type 2 diabetic mice based on UHPLC-MS/MS	25
Characterization of the metabolite of cabozantinib generated from liver microsomes and hepatocytes by ultra-high performance liquid chromatography coupled to quadrupole/orbitrap high resolution mass s	24
Editorial Board	24
A comprehensive strategy for the identification of biologics by liquid-chromatography–mass spectrometry for release testing in a regulated environment	24
Hair-based rapid UPLC-MS/MS analysis of 36 phencyclidine-type substances in forensic cases	24
LC-MS/MS based metabolomic analysis of serum from patients with cerebrovascular stenosis	24
Electrochemistry/mass spectrometry (EC/MS) for fast generation and identification of novel reactive metabolites of two unsymmetrical bisacridines with anticancer activity	24
Development and validation of LC-MS/MS methods for the quantification of 101BHG-D01, a novel, long-acting and selective muscarinic receptor antagonist, and its main metabolite M6 in human plasma, urin	24
UHPLC-HRMS-based serum untargeted lipidomics: Phosphatidylcholines and sphingomyelins are the main disturbed lipid markers to distinguish colorectal advanced adenoma from cancer	24
Screening and identification of Euphorbiae pekinensis Rupr. anti-angiogenic multi-components with UPLC-QTOF-MS in zebrafish	24
Challenges in sample preparation for swellable core technology tablets: Approaches for the removal of polyethylene oxide and optimization of API recovery	24
Separation and purification of glycosides from medicinal plants based on strong polar separation medium with online closed-loop mode	24

Qualitative and quantitative analysis of the component variations of Raphani Semen during the stir-frying process and elucidation of transformation pathways of multiple components	24
Biosensing strategies for the detection of SARS-CoV-2 nucleic acids	23
Study on material basis and anti-hypertensive metabolomics of different extraction methods of the Uncaria rhynchophylla Scrophularia Formula	23
Chemometric evaluation of repeatability of internal standard methods in high-performance liquid chromatography with a Japanese pharmacopoeia assay for indomethacin as an example	23
A feasible HPTLC method for concurrent quantitation of allopurinol-montelukast co-therapy in plasma and evaluation of their hepatic and renal effects in rats: Analytical, biochemical, and histopatholo	23
Determination of free sulfhydryl contents for proteins including monoclonal antibodies by use of SoloVPE	23
Identification and quantification of markers in Azedarach Fructus and Toosendan Fructus	23
Editorial Board	23
Equine in vivo metabolite profiling of the selective androgen receptor modulator LGD-3303 for doping control	23
Amino acids analysis reveals serum methionine contributes to diagnosis of the Kawasaki disease in mice and children	22
Editorial Board	22
Understanding the retention mechanisms of a reversed-phase/anion exchange/cation-exchange column for the separation of epinephrine and norepinephrine	22
Unraveling the mechanisms of Fenugreek seed for managing different gynecological disorders: steroidal saponins and isoflavones revealed as key bioactive metabolites	22
Characterization of antigen presentation capability for neoantigen-based products using targeted LC-MS/MS method	22
Use of qNMR to determine HPLC relative response factors for botanical reference standards used in pharmacopeial monographs	22
Facile synthesis of nickel phosphate nanorods as biomimetic enzyme with excellent electrocatalytic activity for highly sensitive detection of superoxide anion released from living cells	22
Editorial Board	21
Analysis of the polymerized impurities in cefmetazole sodium based on novel separation principle by liquid chromatography tandem ion trap/time-of-flight mass spectrometry	21
Full evaporation headspace gas chromatography with thermal conductivity detection for the direct determination of water in solid pharmaceutical bulk products	21
Optimization of the quantitative protocol for organic acid in fecal samples using gas chromatography-mass spectrometry	21
Editorial Board	21
Study on the hydrolytic degradation behaviour of bictegravir by LC-PDA-Q/TOF-MS/MS NMR and in silico toxicity assessment	21
Validating a sensitive LCMS method for the quantitation of artemisinin in Artemisia spp. including material used in retracted clinical trials	21
Ligand fishing approach to explore Amaryllidaceae alkaloids as potential antiviral candidates targeting SARS-CoV-2 Nsp4	21
HR/MS-based lipidome analysis of rat brain modulated by tolcapone	21
Universal response method for the quantitative analysis of photodegradation impurities in lomefloxacin hydrochloride ear drops by liquid chromatography coupled with charged aerosol detector	21
Precolumn derivatization LC-MS/MS method to simultaneous quantitation of 10 monosaccharides in rat plasma	21
An evaluation of qH NMR: A complementary approach to GC-FID for quantification of Thymol and trans-Anethole in essential oils and supplements	20
Urine proteome changes in a chronic unpredictable mild stress (CUMS) mouse model of major depressive disorder	20
Boron nitride nanotubes for extraction of angiotensin receptor blockers from human plasma	20
Editorial Board	20
“Plant Golden” C. sativus: Qualitative and quantitative analysis of major components in stigmas and petals and their biological activity in vitro	20
Reply to “Letter to the Editor 3,4-Methylenedioxymethamphetamine quantification via benchtop 1H qNMR spectroscopy: Method validation and its application to ecstasy tablets collected at music festivals	20
Simplification of pharmacopoeial liquid chromatography methods for related substances of statins by hyphenated ultraviolet and charged aerosol detection	20
Screening and characterization of potential anti-gout components from Polygonum cuspidatum by integration off-line two-dimensional liquid chromatography-mass spectrometry with affinity ultrafiltration	20
Antiglycation, antioxidant and cytotoxicity activities of crude extract of Turnera ulmifolia L. before and after microencapsulation process	20
Untargeted GC/MS-based approach for identification of anti-inflammatory alkaloids from Hippeastrum elegans (Amaryllidaceae) using a human neutrophil model	20
A multiplex UPLC-MS/MS method for the quantification of three PD-L1 checkpoint inhibitors, atezolizumab, avelumab, and durvalumab, in human serum	20
Development and validation of a LC–MS/MS method for the quantification of phenolic compounds in human saliva after intake of a procyanidin-rich pine bark extract	20
Simultaneous determination of iguratimod and its metabolite in rat plasma using a UPLC-MS/MS method: Application for drug-drug interaction	20
Editorial Board	19
Analyzing proteolytic stability and metabolic hotspots of therapeutic peptides in two rodent pulmonary fluids	19
Recent advances in wearable medical diagnostic sensors and new therapeutic dosage forms for fever in children	19
Tyrosine and tryptophan in urine as biomarkers for prostate cancer: A validation study	19
Identification and characterization of the in-vivo metabolites of the novel soluble epoxide hydrolase inhibitor EC5026 using liquid chromatography quadrupole time of flight mass spectrometry	19
Development of salting-out extraction methodology for the determination of piroxicam from polymeric based nanocarriers and biological samples	19
Hybrid organic/inorganic hybrid surface technology for increasing the performance of LC/MS(MS)-based drug metabolite identification studies: Application to gefitinib and metabolites in mouse plasma an	19
High stability amino-derived reversed-phase/anion-exchange mixed-mode phase based on polysilsesquioxane microspheres for simultaneous separation of compound drugs	19
Molecular classification and clinical diagnosis of acute-on-chronic liver failure patients by serum metabolomics	19
Ruxolitinib photodegradation mechanisms by theoretical and experimental chemistry	19
Development and evaluation of a HILIC-MS method for the determination of amino acid and non-amino acid impurities in histidine	19
Development and validation of a sensitive and simple LC-MS/MS method for simultaneous quantitation of valsartan, sacubitril and sacubitrilat in pediatric population	19
Study on the effect of calibration standards prepared with different matrix on the accuracy of bile acid quantification using LC-MS/MS	18
Validation of an LC-MS/MS assay for the simultaneous determination of bictegravir, doravirine, and raltegravir in human plasma	18
Enhanced urinary stability of peptide hormones and growth factors by dried urine microsampling	18
Application of Analytical Quality by Design to the development and validation of reduced and non-reduced capillary electrophoresis analytical procedures for mAb purity determination	18
Metabolomics and pharmacodynamic analysis reveal the therapeutic role of Prunella vulgaris oil on intrauterine adhesion rats	18
Development of a deep eutectic solvent-based ultrasound-assisted homogenous liquid-liquid microextraction method for simultaneous extraction of daclatasvir and sofosbuvir from urine samples	18
Study on the intervention effect of Epimedium before and after suet-oil-processed on kidney yang deficiency rats based on intestinal flora and fecal metabolomics	18
Optimization of a rapid sample pretreatment for the quantification of COCAINE and its main metabolites in hair through a new and validated GC-MS/MS method	18
Optimization of a robust and reliable FITC labeling process for CE-LIF analysis of pharmaceutical compounds using design of experiments strategy	18
Altered amino acid metabolism between coronary heart disease patients with and without type 2 diabetes by quantitative 1H NMR based metabolomics	18
The comprehensive mechanism underlying Schisandra polysaccharide in AD-like symptoms of Aβ25-35-induced rats based on hippocampal metabolomics and serum lipidomics techniques	18
A Systematic Analysis of the Effect of Extraction Solvents on the Chemical Composition of Extraction Solutions and the Analytical Implications in Extractables and Leachables Studies	18
The POWER saga from 2007 to 2022: An example of a sexual enhancement dietary supplement tainted by different adulterants and still on the market	18
Exploring the anti-ischemic stroke potential of wogonoside: Insights from Nrf2/Sirt3 signaling pathway and UPLC-TripleTOF-MS/MS-based metabolomics	18
Enantioseparation of β-receptor blockers and the enantioselective degradation of carvedilol in soil	18
Development and clinical validation of a simple and fast UPLC-ESI-MS/MS method for simultaneous quantification of nine kinase inhibitors and two antiandrogen drugs in human plasma: Interest for their	17
The pharmacokinetic study of Tanreqing and the interaction with cefixime in rat model of pneumonia by validated UPLC-MS/MS	17
Drug discovery from natural products – Old problems and novel solutions for the treatment of neurodegenerative diseases	17
Automated ELISA for potency measurements of therapeutic antibodies and antibody fragments	17
Metabolomics study of Shenling Baizhu Powder in the treatment of multiple organ dysfunction syndrome in the elderly (MODSE) with malnutrition	17
Development of an electrochemical sensor for the quantification of ascorbic acid and acetaminophen in pharmaceutical samples	17
Determination of potentially genotoxic impurities in crotamiton active pharmaceutical ingredient by gas chromatography	17
1H NMR-based metabolomic study of striatal injury in rats with copper-loaded Wilson's disease by Chinese and Western medicine intervention	17
Obesity influences the microbiotic biotransformation of chlorogenic acid	17
Development and validation of an LC-MS/MS methodology for the quantification of thyroid hormones in dko MCT8/OATP1C1 mouse brain	17
Development of visualization and analysis methods for evaluating intratumoral nanoparticle kinetics for tumor-targeted drug delivery using Förster resonance energy transfer in vivo live imaging and ti	17
Development of bioassay platforms for biopharmaceuticals using Jurkat-CAR cells by AICD	17
Systematic investigation of the pharmacological mechanism of Tanreqing injection in treating respiratory diseases by UHPLC/Q-TOF-MS/MS based on multiple in-house chemical libraries coupled with networ	17

A validated UHPLC-MS/MS method for quantification of total and free tedizolid concentrations in human plasma	17
Overview of therapeutic drug monitoring of immunosuppressive drugs: Analytical and clinical practices	17
An accurate and reliable analytical strategy for simultaneous determination of target furanocoumarins and flavonoids in cosmetic and pharmaceutical samples by ultra-high performance supercritical flui	17
A photonic dual nano-hybrid assay for detection of cell-free circulating mitochondrial DNA	17
Determination of CYP450 activities in diabetes mellitus rats by a UHPLC-MS/MS method	17
Quantification of anti-SARS-CoV-2 antibodies in human serum with LC-QTOF-MS	17
Purification free N-glycan analysis by capillary zone electrophoresis: Hunt for the lost glycans	17
Volumetric dried blood microsampling for monitoring imatinib mesylate therapy: Method development and clinical application in patients with chronic myeloid leukemia	17
Development of a colloidal gold immunochromatographic strip for rapid and sensitive detection of nicotine	17
Comprehensive quality evaluation of Aconiti Lateralis Radix Praeparata based on pseudotargeted metabolomics and simultaneous determination of fifteen components, and development of new processed produ	17
Chemical composition, biological properties and bioinformatics analysis of two Caesalpina species: A new light in the road from nature to pharmacy shelf	17
A two‑sample Mendelian randomization study of lipidome and lung cancer	16
Highly sensitive ultra-high-performance liquid chromatography coupled with tandem mass spectrometry method for the multiplex analysis of levosimendan and its metabolites OR-1855 and OR-1896 in human p	16
Stress degradation study on entrectinib and characterization of its degradation products using HRMS and NMR	16
Quality evaluation of Pterocephali Herba through simultaneously quantifying 18 bioactive components by UPLC-TQ-MS/MS analysis	16
Drugs detection in fingerprints	16
LC-MS/MS determination of atropine toxicity: Pre-analytical effect of blood collection tube and analytical matrix	16
Evaluation of critical factors in the preparation of saliva sample from healthy subjects for metabolomics	16
New insights into the chemistry and anticancer activity of Ophiocordyceps xuefengensis	16
Determination of carbamazepine profile in human plasma by GC-MS	16
Challenges encountered in the enantioselective analysis of new psychoactive substances exemplified by clephedrone (4-CMC)	16
Identification of degradation products in flumazenil using LC-Q-TOF/MS and NMR: Degradation pathway elucidation	16
Integrated network pharmacology, mass cytometry and multi-omics analysis the effect of Jingfang granule on intestinal immune disorder in mice with cold-dampness syndrome	16
Integrated untargeted metabolomics and bioactivity studies as new insights into the chemotaxonomy of Hura crepitans specimens from Peru and Sub-Saharan Africa	16
Implementation and validation of a UHPLC-MS/MS method for quantification of the endocannabinoids AEA and 2-AG in cerebral interstitial fluid and plasma	16
Integrated metabolomics and gut microbiota analysis to explore potential mechanism of Qi-Huo-Yi-Fei formula against chronic obstructive pulmonary disease	16
Differentiation of the chronic lymphocytic leukemia response to ibrutinib and acalabrutinib treatment by single-cell MALDI-TOF MS imaging	16
Successful LC-MS/MS assay development and validation for determination of valproic acid and its metabolites supporting proactive pharmacovigilance	16
Development and validation of an UPLC-MS/MS method for simultaneous determination of fifteen targeted anti-cancer drugs in human plasma and its application in therapeutic drug monitoring	16
First analytical confirmation of drug-induced crystal nephropathy in felines caused by GS-441524, the active metabolite of Remdesivir	16
State-of-the-art chromatographic and mass spectrometric techniques in heparin structural analysis	16
Biodegradability of dietary supplements: Advanced analytical methods to study the environmental fate of artificial sweeteners and dyes	16
Raman spectroscopy: A promising analytical tool used in human reproductive medicine	16
First-in-human study to assess the safety, tolerability, and pharmacokinetics of intravenous SHPL-49 following single- and multiple-ascending-dose administration in healthy adults	16
Steroid profiling by UHPLC-MS/MS in dried blood spots collected from healthy women with and without testosterone gel administration	15
The chemical profile and seasonal variation of the composition of the phenolic acids in different plant parts of Centaurea sp.	15
Altered metabolome and microbiome features provide clues in predicting recurrence of ulcerative colitis	15
1H NMR profiling and chemometric analysis as an approach to predict the leishmanicidal activity of dichloromethane extracts from Lantana camara (L.)	15
Integrated component identification, network pharmacology, and experimental verification revealed mechanism of Dendrobium officinale Kimura et Migo against lung cancer	15
Impact of three different peak picking software tools on the quality of untargeted metabolomics data	15
LC-HRMS and NMR studies for characterization of forced degradation impurities of ponatinib, a tyrosine kinase inhibitor, insights into in-silico degradation and toxicity profiles	15
Nanostructured sensor platform based on organic polymer conjugated to metallic nanoparticle for the impedimetric detection of SARS-CoV-2 at various stages of viral infection	15
Detection of major psychoactive compounds (safrole, myristicin, and elemicin) of nutmeg in human serum via GC–MS/MS using MonoSpin® extraction: Application in a nutmeg poisoning case	15
Integrative pharmacology powers the detection of active components and mechanism underlying Wang Bi granules in rheumatoid arthritis	15
Spectrum-effect relationship between UPLC-Q-TOF-MS fingerprint and anti-AUB effect of Clinopodium chinense (Benth.) O. Kuntze	15
Identification and structural elucidation of a new cetrorelix methylene dimer impurity in cetrorelix acetate by using LC-MS/MS	15
Facile synthesis of surface functionalized Pd2+@P-CDP/COFs for highly sensitive detection of norfloxacin drug based on the host-guest interaction	15
Untargeted lipidomics reveals specific lipid profiles in COVID-19 patients with different severity from Campania region (Italy)	15
An analytical approach to determining pethidine: An investigation of 18 patients’ urine	15
Analytical quality by design approach for the determination of imidazole in sildenafil API and its formulations using zwitterionic HILIC stationary phase	15
Identification and characterization of the chemical constituents in the roots of Ilex asprella by high performance liquid chromatography coupled to electrospray ionization and quadrupole time-of-fligh	15
Proteomic analysis reveals that Polygonatum cyrtonema Hua polysaccharide ameliorates mice muscle atrophy in chemotherapy-induced cachexia	15
The first RP-UHPLC method for simultaneous quantification of abiraterone acetate, its four degradants, and six specified process impurities and correct identification of all analytes based on molecula	15
Novel quality control strategies for the determination of 25-hydroxyvitamin D by LC-MS/MS	14
Optimization of pretreatment methods for cerebrospinal fluid metabolomics based on ultrahigh performance liquid chromatography/mass spectrometry	14
Exploring the composition and properties of Centella asiatica metabolites and investigating their impact on BSA glycation, LDL oxidation and α-amylase inhibition	14
A method for assessing plasma free fatty acids from C2 to C18 and its application for the early detection of colorectal cancer	14
Alternative method for canagliflozin oxidation analysis using an electrochemical flow cell – Comparative study	14
A high-throughput analytical method for multiple DNA targets based on microdroplet PCR coupled with DGGE	14
Chromatographic measurement of 3-hydroxyanthranilate 3,4-dioxygenase activity reveals that edaravone can mitigate the formation of quinolinic acid through a direct enzyme inhibition	14
Molecularly imprinted polymers for arbutin and rutin by modified precipitation polymerization and their application for selective extraction of rutin in nutritional supplements	14
Stability of diazepam’s phase II metabolites in dried blood spots on filter paper	14
Novel aspects of taxifolin pharmacokinetics: Dose proportionality, cumulative effect, metabolism, microemulsion dosage forms	14
Exploring the sulfate patterns of chondroitin sulfate/dermatan sulfate and keratan sulfate in human pancreatic cancer	14
Quantitative study of ternary polycrystalline mixtures of prulifloxacin based on Raman spectra and Raman imaging maps	14
Validation and application of a quantitative liquid chromatography tandem mass spectrometry assay for the analysis of rifapentine and 25-O-desacetyl rifapentine in human milk	14
Mass balance method for SI-traceable purity assignment of synthetic oxytocin	14
Development and application of immunoassays for rapid quality control of the antimalarial drug combination artesunate-mefloquine	14
Metabolic and lipidomic characterization of radioresistant MDA-MB-231 human breast cancer cells to investigate potential therapeutic targets	14
Development and validation of a ligand-binding assay for quantification of the F(ab')2 antivenom of Daboia russelii siamensis in human serum and its application to a phase I clinical study	14
Influence of drying process on furostanoside and spirostanoside profiles of Paridis Rhizoma by combination of HPLC, UPLC and UPLC-QTOF-MS/MS analyses	14
Identification and structural elucidation of an oxidation product generated during stability studies of Cabergoline drug product	14
Analytical approaches to assess metabolic changes in psoriasis	14
A new strategy based on PCA for inter-batches quality consistency evaluation	14
Comparison of the metabolome in urine prior and eight weeks after radical prostatectomy uncovers pathologic and molecular features of prostate cancer	14
Rapid screening of imidacloprid residue in grains and medicinal herbs: A newly designed hapten and monoclonal antibody	14
Quantitative determination of ICG-001 in rat plasma using HPLC-MS/MS: A pharmacokinetic study	14
High-level structural analysis of proanthocyanidins using full collision energy ramp-MS2 spectrum	14
Greening microwave-assisted digestion method using hydrogen peroxide for determination of elemental impurities by ICP-OES in antihypertensive active pharmaceutical ingredients	13
Experimental design of a stable isotope labeling derivatized UHPLC–MS/MS method for the detection/quantification of primary/secondary bile acids in biofluids	13
A sensitive UPLC-MS/MS method for the simultaneous determination of the metabolites in the tryptophan pathway in rat plasma	13
Metabolism of dipentylone in zebrafish and human liver microsomes determined by liquid chromatography–high resolution mass spectrometry	13
Structural characterization of novel hydrolytic and oxidative degradation products of acalabrutinib by LC-Q-TOF-MS, H/D exchange and NMR	13
Propofol-induced in-situ formation of silver nanoparticles: A sensing colorimetric method	13
Separation and identification of a complex flurbiprofen-polyethylene glycol mono- and diester mixture via a hyphenated HPLC-DAD-HRMS/SPE NMR system	13
Towards a holistic view of tablet quality, an extensive study on paracetamol tablets with nuclear magnetic resonance using similarity calculations, differential NMR and hierarchical cluster analysis	13
Rapid determination of essential oils functional groups using compositional methods and VisNIR spectroscopy	13
Characterization and comparison of polysaccharides from Achyranthes bidentata, Cyathula officinalis and Achyranthes aspera by saccharides mapping	13
Enantioseparation and quantitative analysis of three alkaloids in Rhizoma Corydalis by chiral LC-MS/MS	13
Detection of antibody-conjugate payload in cynomolgus monkey serum by a high throughput capture LC–MS/MS bioanalysis method	13
Development of the stability-indicating method, structural elucidation of new photodegradation products from terconazole by LC-MS TOF, and in vitro toxicity	13
Separation of chiral and achiral impurities in paroxetine hydrochloride in a single run using supercritical fluid chromatography with a polysaccharide stationary phase	13
A high-throughput droplet digital PCR system aiming eight DNA methylation targets for age prediction	13
Identifying potential ligands specifically binding to beta1-adrenoceptor from Radix Aconiti Lateralis Praeparata extract by affinity chromatographic method	13
Small volume rapid equilibrium dialysis (RED) measures effects of interstitial parameters on the protein-bound fraction of topical drugs	13