Journal of Pharmaceutical and Biomedical Analysis

Papers
(The TQCC of Journal of Pharmaceutical and Biomedical Analysis is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)
ArticleCitations
Guilty by dissociation: Part C: Enantiomeric separation of diphenidine-derived new psychoactive substances (NPS) by polar organic chiral high performance liquid chromatography (HPLC) on polysaccharide383
LC-MS/MS determination of atropine toxicity: Pre-analytical effect of blood collection tube and analytical matrix146
Molecularly imprinted polymers for arbutin and rutin by modified precipitation polymerization and their application for selective extraction of rutin in nutritional supplements113
Determination of famprofazone, amphetamine and methamphetamine in liver samples using enzymatic cell dispersion and SPE-LC-ESI-MS105
Rapid detection of rocuronium based on host/guest complex between a pyrene derivative and sugammadex85
A high-throughput analytical method for multiple DNA targets based on microdroplet PCR coupled with DGGE70
Separation and identification of a complex flurbiprofen-polyethylene glycol mono- and diester mixture via a hyphenated HPLC-DAD-HRMS/SPE NMR system64
Metabolomic and sphingolipidomic profiling of human hepatoma cells exposed to widely used pharmaceuticals62
Exploring the gut microbiota mediated biotransformation of Senecio scandens Buch.-Ham.: Insights from metabolite spectrum with UHPLC-Q-Orbitrap HRMS and bioinformatics analysis of gut microbiota metab57
Comparative analysis of chemical components in fruits of Chebulae Fructus and its pulp based on chromatographic technology coupled with multivariate chemometric methods53
Metabolomic and biochemical changes in the plasma and liver of toxic milk mice model of Wilson disease51
Editorial Board49
Study on the intervention effect of Epimedium before and after suet-oil-processed on kidney yang deficiency rats based on intestinal flora and fecal metabolomics46
An evaluation of qH NMR: A complementary approach to GC-FID for quantification of Thymol and trans-Anethole in essential oils and supplements44
New insights into the chemistry and anticancer activity of Ophiocordyceps xuefengensis44
Equine in vivo metabolite profiling of the selective androgen receptor modulator LGD-3303 for doping control43
Editorial Board42
Precolumn derivatization LC-MS/MS method to simultaneous quantitation of 10 monosaccharides in rat plasma40
Development of salting-out extraction methodology for the determination of piroxicam from polymeric based nanocarriers and biological samples40
Editorial Board39
Development and evaluation of a HILIC-MS method for the determination of amino acid and non-amino acid impurities in histidine39
Editorial Board39
Detection and differentiation of active and inactive isoforms of coagulation factors II, VII, IX, and X in prothrombin complex concentrate by mass spectrometry37
GC and HPLC-RID method development and validation for the determination of twelve related substances, including several novel compounds in tetrabenazine36
l-Asparaginase and HCP quantification by SWATH LC-MS/MS for new and improved purification step in Erwinia chrysanthemi l-asparaginase manufacture36
Chromatographic analysis and pKa evaluation of active pharmaceutical ingredients in anti-metastatic breast cancer: Green vs. conventional RPLC36
Qualitative and quantitative evaluations of Chuanxiong dispensing granules by using chemical fingerprint in combination with chemometrics methods36
A comprehensive strategy for the identification of biologics by liquid-chromatography–mass spectrometry for release testing in a regulated environment36
Qualitative and quantitative analysis of the component variations of Raphani Semen during the stir-frying process and elucidation of transformation pathways of multiple components35
Metabolomics-based investigation of the chemical composition changes in Mongolian medicinal plant Euphorbia pekinensis before and after processing with Chebulae Fructus35
Drug discovery from natural products – Old problems and novel solutions for the treatment of neurodegenerative diseases35
Amanitin determination in bile samples by UHPLC-MS: LR-MS and HR-MS analytical performance35
NMR-based metabolomics of dried berries in comparison with dietary supplements35
The chemical profile and seasonal variation of the composition of the phenolic acids in different plant parts of Centaurea sp.34
Integrating 16S rDNA sequencing analysis and targeted metabolomics to explore the mechanism of Xiexin Tang in treating atherosclerosis mice induced by high-fat diet34
Development and validation of derivatization-based LC-MS/MS method for quantification of short-chain fatty acids in human, rat, and mouse plasma34
A preclinical study on online monitoring of exhaled ciprofol concentration by the ultraviolet time-of-flight spectrometer and prediction of anesthesia depth in beagles34
Qualitative and quantitative comparison of flavor chemicals in tobacco heating products, traditional tobacco products and flavoring capsules34
Illuminating green fluorescent protein: Characterizing tri-peptide fluorescent chromophore, probing reactivity of cysteines, and unveiling site-directed modifications through mass spectrometry33
Electrochemistry/mass spectrometry (EC/MS) for fast generation and identification of novel reactive metabolites of two unsymmetrical bisacridines with anticancer activity33
Recent advances in wearable medical diagnostic sensors and new therapeutic dosage forms for fever in children32
Polysaccharides from Balanophora harlandii Hook: Isolation, characterization, and anti-inflammation activities32
Identification of plasma biomarkers for non-invasive diagnosis of hepatitis B cirrhosis32
A feasible HPTLC method for concurrent quantitation of allopurinol-montelukast co-therapy in plasma and evaluation of their hepatic and renal effects in rats: Analytical, biochemical, and histopatholo32
A simplified non-reduced peptide mapping method with faster and efficient enzymatic digestion for characterization of native disulfide bonds in monoclonal and bispecific antibodies30
High-level structural analysis of proanthocyanidins using full collision energy ramp-MS2 spectrum30
Development and evaluation of a new test kit for determination of immunosuppressants in blood by UHPLC-MS/MS30
Development and validation of an HPLC-MS/MS method for the quantification of the anti-leishmanial drug miltefosine in human skin tissue30
An efficient approach to probe bioactive components of herbal patches by 2D-carbon microfiber fractionation and multi-chamber membrane separation electrophoresis: Spatholobus suberectus Dunn as a case29
Analytical approaches to assess metabolic changes in psoriasis29
Development of enantioselective high-performance liquid chromatography-tandem mass spectrometry method for the quantitative determination of 3,4-methylenedioxy-methamphetamine (MDMA) and its phase-1 m29
Enantioseparation and quantitative analysis of three alkaloids in Rhizoma Corydalis by chiral LC-MS/MS29
Determination of 13 potential anti-obesity agents in hair by dispersive liquid-liquid microextraction-assisted UHPLC-MS/MS29
The importance of method validation in herbal drug research29
Emerging analytical techniques for pharmaceutical quality control: Where are we in 2022?28
Determination of lithium concentration in capillary blood using volumetric dried blood spots28
Qualitative and quantitative analysis of major components in Abelmoschus manihot flowers treated with different drying methods using UHPLC Q-exactive MS and HPLC-PDA28
Advanced design of chemically modified electrodes for the electrochemical analysis of uric acid and xanthine28
Integrated cartilage metabolomics and proteomics analysis reveals the therapeutic effect of Wenjing Tongluo Decoction on Knee osteoarthritis rats28
Quality assessment of Curcuma dietary supplements: Complementary data from LC-MS and 1H NMR28
Development of organic three-phase laminar flow microfluidic chip for extraction of ginsenosides from Panax ginseng28
Stability of the antibiotic ceftaroline fosamil with focus on degradation products and decomposition pathways – Integrative analysis by LC-DAD, ESI-QTOF and in silico prediction28
A ratiometric electrochemical biosensor via alkaline phosphatase mediated dissolution of nano-MnO2 and Ru(III) redox recycling for the determination of dimethoate27
Proteomic analysis reveals that Polygonatum cyrtonema Hua polysaccharide ameliorates mice muscle atrophy in chemotherapy-induced cachexia27
Recent progress in the graphene-based biosensing approaches for the detection of Alzheimer's biomarkers27
Bifunctional electrochemical biosensor based on PB-MXene films for the real-time analysis and detection of living cancer cells27
The development and validation of a novel LC-MS/MS method for the simultaneous quantification of Molnupiravir and its metabolite ß-d-N4-hydroxycytidine in human plasma and saliva27
Identification of ADB-5’Br-BINACA in plant material and analytical characterization using GC-MS, LC-QTOF-MS, NMR and ATR-FTIR27
Automated ELISA for potency measurements of therapeutic antibodies and antibody fragments27
Development and validation of a ligand-binding assay for quantification of the F(ab')2 antivenom of Daboia russelii siamensis in human serum and its application to a phase I clinical study27
First-in-human study to assess the safety, tolerability, and pharmacokinetics of intravenous SHPL-49 following single- and multiple-ascending-dose administration in healthy adults27
Integrated metabolomics and gut microbiota analysis to explore potential mechanism of Qi-Huo-Yi-Fei formula against chronic obstructive pulmonary disease26
Integrated UHPLC-MS untargeted metabolomics and gut microbe metabolism pathway-targeted metabolomics to reveal the prevention mechanism of Gushudan on kidney-yang-deficiency-syndrome rats26
Multi-attribute method performance profile for quality control of monoclonal antibody therapeutics26
Combined untargeted metabolomics and network pharmacology approaches to reveal the therapeutic role of withanolide B in psoriasis26
A sensitive UPLC-MS/MS method for the simultaneous determination of the metabolites in the tryptophan pathway in rat plasma26
Development and validation of an UPLC-MS/MS method for simultaneous determination of fifteen targeted anti-cancer drugs in human plasma and its application in therapeutic drug monitoring26
Editorial Board25
Too much or too little caffeine? Determination of content in thermogenic capsules by quantitative 1H nuclear magnetic resonance (qNMR)25
A revised version of the Iwaoka’s assay: Application of hyphenated techniques25
Immunomodulatory effect of Liangyi paste on the gut microbiota of mice25
Development of a derivatization RP-HPLC method for determination of sulfuryl chloride in chlorosulfonic acid for gefapixant citrate manufacture25
Editorial Board25
Effects of compound Anoectochilus roxburghii (Wall.) Lindl. oral liquid on relative metabolic enzymes and various biochemical indices in Wistar rats with isoniazid-induced liver injury24
Integrated molecular networking strategy enhance the accuracy and visualization of components identification: A case study of Ginkgo biloba leaf extract24
Chemometric assisted natural DES based VA-DLLME-LC-MS/MS method for the quantitative determination of Garcinol in biofluids/tissues: A practical application to pharmacokinetics and biodistribution stu24
Optimization of bronchoalveolar lavage fluid volume for untargeted lipidomic method and application in influenza A virus infection24
Comprehensive evaluation and screening of phytochemical compounds and their hypolipidemic activities of lotus leaf based on HPLC-Q-TOF-MS and spectral-effect analysis24
The protective effect of rutin against lipopolysaccharide induced acute lung injury in mice based on the pharmacokinetic and pharmacodynamic combination model24
HPLC methods for studying pharmacokinetics of tivozanib and in vitro metabolic interaction with dexamethasone in rat24
Tracking the physicochemical stability of teduglutide (Revestive®) clinical solutions over time in different storage containers23
Variable temperature-nuclear magnetic resonance experiment and high-resolution MS/MSn measurement of hydroxycarbodenafil, and its PDE5 inhibitory activity23
Molecular imprinting-based sensors: Lab-on-chip integration and biomedical applications23
An effective strategy for distinguishing the processing degree of Polygonum multiflorum based on the analysis of substance and taste by LC-MS, ICP-OES and electronic tongue23
A magnetic ionic liquid based vortex-assisted dispersive liquid-liquid microextraction coupled with back-extraction for the enrichment of fluoroquinolone antibiotics23
Qualitative and quantitative comparison of different commercially available 1–84 parathyroid hormone proteins to the WHO international standard 95/646 using orthogonal methods23
Plasma metabolomics identifies S-adenosylmethionine as a biomarker and potential therapeutic target for vascular aging in older adult males23
Identification of potential drug targets for four site-specific cancers by integrating human plasma proteome with genome23
Direct infusion–tandem mass spectrometry combining with data mining strategies enables rapid chemome characterization of medicinal plants: A case study of Polygala tenuifolia23
Metabolic profiling and pharmacokinetic studies of sinapine thiocyanate by UHPLC-Q/TOF-MS and UHPLC-MS/MS23
HPLC-UV method validation for quantification of β-carotene in the development of sustained release supplement formulation containing solid dispersion-floating gel in situ22
Combination of histological and metabolomic assessments to evaluate the potential pharmacological efficacy of saikosaponin D22
Joint proteomic and metabolomic analysis reveals renal metabolic remodeling of chronic heart failure mice22
Simultaneous determination of ceftazidime and pyridine in human plasma by LC-UV22
Whole-cell aptamer-based techniques for rapid bacterial detection: Alternatives to traditional methods22
Development and validation of a simple and affordable LC-UV method for identification and assay of selected antimicrobial medicines22
The effective compounds and mechanisms of Cang-Fu-Dao-Tan Formula in treating polycystic ovary syndrome based on UPLC/Q-TOF-MS/MS, network pharmacology and molecular experiments22
Metabolomics research on treatment of primary liver cancer with Cortex Juglandis Mandshuricae on LC-MS/MS technology22
Omics analysis unveils changes in the metabolome and lipidome of Caenorhabditis elegans upon polydopamine exposure21
Development of a reliable cell-based reporter gene assay to measure the bioactivity of anti-HER2 therapeutic antibodies21
UPLC-Q-TOF/MS-based study on chemical composition, in vivo metabolites, and tissue distribution of ethanol extract of Ganoderma lucidum21
Perampanel dosage in plasma samples: development and validation of a novel HPLC method with combined UV-Fluorescence detection21
Biotransformation and brain distribution of the anti-COVID-19 drug molnupiravir and herb-drug pharmacokinetic interactions between the herbal extract Scutellaria formula-NRICM10121
Analysis of pharmaceutical drug oligomers by selective comprehensive two-dimensional liquid chromatography-high resolution mass spectrometry21
A combination of amino-functionalized fibrous silica (KCC-1-NH2)/effectively and efficiently oxidized graphene oxide (EEGO) nanocomposite for dispersive solid-phase extraction, pre-concentration and f21
An enzyme immunoassay to determine human chorionic gonadotropin (HCG) in serum and urine samples using an ultra-microanalytical system21
Study on the active ingredients and mechanism of Huyang Yangkun Formula for treating premature ovarian insufficiency via chemical profiling, network pharmacology, and experimental validation21
Rapid identification and quantification of Pseudostellaria heterophylla with its adulterants by HPLC-CAD fingerprint combined with improved quantitative analysis of multi-components by single marker (21
Multi-omics analysis of kidney, bone and bone marrow explored potential mechanisms of Erzhi Wan against osteoporosis with kidney-Yin deficiency21
A strategy takes “Yiqing” tablets as an example to carry out simpler multi-component quantification and use fingerprint technology for comprehensive quality consistency evaluation21
Determination of five mTOR inhibitors in human plasma for hepatocellular carcinoma treatment using QuEChERS-UHPLC-MS/MS21
Development and validation of a liquid chromatographic-tandem mass spectrometric assay for the quantification of cabotegravir and rilpivirine from dried blood spots21
Effective enrichment and separation of three flavonoids from Ohwia caudata (Thunberg) H. Ohashi using magnetic layered double hydroxide/ZIF-8 composites and pCEC21
Simultaneous and rapid analysis of chiral Danshensu and its ester derivatives by supercritical fluid chromatography21
Liquid chromatographic study of two structural isomeric pentacyclic triterpenes on reversed-phase stationary phase with hydroxypropyl-β-cyclodextrin as mobile phase additive21
A corneal-PAMPA-based in silico model for predicting corneal permeability21
Development and validation of a label-free HPLC-CAD method to determine total sialic acid in therapeutic proteins21
RP-HPLC separation of interconvertible rotamers of a 5-tetrahydroisoquinolin-6-yl-pyridin-3-yl acetic acid derivative and confirmation by VT NMR and DFT study20
Comparative binding studies of bacosine with human serum albumin and α-1-acid glycoprotein biophysical evaluation and computational approach20
Biological analysis of constituents in Spatholobi Caulis by UFLC-MS/MS: Enhanced quantification and application to permeability properties study in Caco-2 cell monolayer model20
Testing for clomiphene in keratinous matrices using LC–MS/MS in doping purpose: Is a single intake of clomiphene detectable in hair and nail clippings?20
Pharmacokinetics of two triterpenoid saponins and three flavonoids in Astragalus membranaceus leaves by UHPLC-MS/MS20
Distinct chemical degradation pathways of AAV1 and AAV8 under thermal stress conditions revealed by analytical anion exchange chromatography and LC-MS-based peptide mapping20
A comprehensive method for quality evaluation of Tibetan medicine Synotis solidaginea by integrating UHPLC-Q-Orbitrap MS chemical profiling and UHPLC-DAD multi-components quantification20
Analysis of genotoxic N-nitrosamines in active pharmaceutical ingredients and market authorized products in low abundance by means of liquid chromatography – tandem mass spectrometry20
Monitoring of alcohol-based hand rubs in SARS-CoV-2 prevention by HS-GC/MS and electrochemical biosensor: A survey of commercial samples20
Urinary metabonomics study of anti-depressive mechanisms of Millettia speciosa Champ on rats with chronic unpredictable mild stress-induced depression20
Lipidomic profiling of amniotic fluid reveals aberrant fetal lung development and fetal growth disrupted by lipid disorders during gestational asthma20
THC and THC-COOH hair concentrations: Influence of age, gender, consumption habits, cosmetics treatment, and hair features20
A simple and sensitive differential digestion method to analyze adeno-associated virus residual host cell proteins by LC-MS20
Molecular quantification for differentiation of fresh and dried Jinqian Baihua She19
Corrigendum to “Dissecting the antitumor effects of Scutellaria barbata: Initial insights into the metabolism of scutellarin and luteolin by gut microbiota” [J. Pharm. Biomed. Anal. 248 (2024) 116325]19
Peak shape enhancement using diethylamine in hydrophilic liquid interaction chromatography: Application in simultaneous determination of methionine and paracetamol19
Platform headspace gas chromatography method for high-throughput determination of residual solvents in pharmaceutical materials19
Development and optimization of a high-throughput LC-MS/MS method for the simultaneous determination of Exatecan and its Cathepsin B-sensitive prodrug, and ARV-825 in rat plasma: Application to pharma19
Editorial Board19
Quantification of endogenous Angiotensin 1-10, 1-9, 1-8, 1-7, and 1-5 in human plasma using micro-UHPLC-MS/MS: Outlining the importance of the pre-analytics for reliable results19
Confined CHA-HCR system for sensitive and specific detection of ANXA2 mRNA in adenomyosis tissues19
UPLC-ESI-Q-TOF-MS/MS based metabolomics investigation on chemical constituent consistency of Zhenwu Decoction before and after compatibility19
Application of LEDA algorithm for the recognition of P-glycoprotein and Carbonic Anhydrase hybrid inhibitors and evaluation of their plasma stability by HPLC-MS/MS analysis19
Editorial Board19
Editorial Board19
Reverse traceability analysis of estrogenic active ingredients in Cuscutae semen based on intestinal and hepatic metabolism19
Influence of the quality of capsule shell on the non-invasive monitoring of medicines using Terizidone as an example19
Identifying biomarkers for nasopharyngeal carcinoma diagnosis and chemoradiotherapy response using serum endogenous small molecules profiling19
Development and validation of an LC–MS/MS generic assay platform for small molecule drug bioanalysis19
Fluorescent "turn-on" aptamer sensor for sensitive and reliable detection of Golgi glycoprotein 73 based on nitrogen-doped graphene quantum dots and molybdenum disulfide nanosheets18
Degradation kinetics and characterization of major degradants of binimetinib employing liquid chromatography-high resolution mass spectrometry18
The screened compounds from Ligustri Lucidi Fructus using the immobilized calcium sensing receptor column exhibit osteogenic activity in vitro18
Development of a rapid and sensitive LC-MS/MS assay for the quantification of commonly abused drugs in Asia in a micro-segment of a single hair using microwave-assisted extraction and dansyl chloride d18
Comparisons of pharmacokinetics and tissue distribution of six major bioactive components of the herbal pair Alpinia officinarum-Cyperus rotundus in normal and primary dysmenorrhea rats18
Determination of ten antipsychotics in blood, hair and nails: Validation of a LC–MS/MS method and forensic application of keratinized matrix analysis18
A strategy integrated DNA barcoding with metabolomics for screening distinguishable combinatorial chemical quality marker between Pheretima aspergillum and Pheretima vulgaris Chen18
Simultaneous quantification of seven B vitamins in human faeces by stable isotope label-based high-performance liquid chromatography-tandem mass spectrometry18
Liquid chromatography-tandem mass spectrometry analysis of delamanid and its metabolite in human cerebrospinal fluid using protein precipitation and on-line solid-phase extraction18
Discovery of bioactive compounds targeting endothelin A receptor and angiotensin II type 1 receptor in Gegen Qinlian decoction by co-immobilized receptor chromatography18
Targeting tryptophan metabolism reveals Clematichinenoside AR alleviates triptolide-induced hepatotoxicity18
Chip-based digital PCR as a direct quantification method for residual DNA in mRNA drugs18
Validation of a rapid liquid chromatography tandem mass spectrometric method for the quantitative analysis of vistusertib18
Application of microdialysis combined with lipidomics to analyze fatty acid metabolic changes in the disease process of rheumatoid arthritis18
Revealing metabolic alterations in brucellosis patients by targeted metabolomics18
The quality of drugs and drug products – Always guaranteed?17
Deciphering the metabolic profile and anti-colorectal cancer mechanism of Capilliposide A using ultra performance liquid chromatography mass spectrometry combined with non-targeted metabolomics studie17
Development and validation of an analytical method for the simultaneous quantitation of posaconazole Form I and Form-S in oral suspensions17
Editorial Board17
Evaluation of 4 quantification methods for monitoring 16 antibiotics and 1 beta-lactamase inhibitor in human serum by high-performance liquid chromatography with tandem mass spectrometry detection17
Simultaneous LC-MS/MS quantification of oxycodone, tramadol and fentanyl and their metabolites (noroxycodone, oxymorphone, O- desmethyltramadol, N- desmethyltramadol, and norfentanyl) in human plasma 17
Study on the white frost formation mechanism during storage of Phyllanthus emblica Linn. fruit based on component analysis and spatial metabolomics17
Characterization of low-level D-amino acid isomeric impurities of Semaglutide using liquid chromatography-high resolution tandem mass spectrometry17
Alterations in serum metabolic profiles of early-stage hepatocellular carcinoma patients after radiofrequency ablation therapy17
Hyaluronic acid skin penetration evaluated by tape stripping using ELISA kit assay17
Determination of paracetamol and its metabolites via LC-MS/MS in dried blood volumetric absorptive microsamples: A tool for pharmacokinetic studies17
Biotransformation of 5-methoxy-N-isopropyl-N-methyltryptamine by zebrafish and human liver microsome with high-resolution mass spectrometry17
A universal method for profiling and characterization of oligosaccharides in traditional Chinese medicines17
Editorial Board17
Phytochemical profiling of Symplocos tanakana Nakai and S. sawafutagi Nagam. leaf and identification of their antioxidant and anti-diabetic potential17
A sensitive UPLC-MS/MS method for simultaneous quantification of one-carbon metabolites & co-factors in human plasma16
Salvia officinalis and Lippia triphylla: Chemical characterization and evaluation of antidepressant-like activity16
Analysis of the intracellular localization of amiodarone using live single-cell mass spectrometry16
NMR-based foodomics of common tubers and roots16
Application of electron paramagnetic resonance spectroscopy to examine free radicals formed in indapamide and torasemide storage under UV irradiation and at the higher temperatures which appear under 16
Development of UPLC–MS/MS method for studying the pharmacokinetic interactions of fuzuloparib with curcumin in rats16
Targeted characterization and guided isolation of chemical components in Scrophulariae Radix based on LC-MS16
Validation of a fast and sensitive UPLC-MS/MS quantitative method for N-acyl taurine analysis in biological samples16
LC-PDA-QTof-MS characterization of the stress degradation products of Zanubrutinib: A novel BTK inhibitor16
Ion pair-based mobile phase additives to improve the separation of alkaloids in supercritical fluid chromatography16
Exploration of the intestinal flora to reveal the important contribution of Radix Astragali to Huangqi Jianzhong Tang in treating chronic atrophic gastritis rats16
Development of an hollow fiber solid phase microextraction method for the analysis of unbound fraction of imatinib and N-desmethyl imatinib in human plasma16
HPLC-fluorescence detection for stability of harringtonine, and identification of degradation products by UPLC-Q-TOF-MS16
Superheated reversed phase chromatography with ultrashort columns for the analysis of therapeutic proteins16
Rapid detection and quantification of falsified Viagra using cloud-based portable NIR technology and machine learning16
Rapid detection of phenytoin sodium by partial-least squares and linear regression models combined with surface-enhanced Raman spectroscopy16
Sigma receptor and aquaporin modulators: chiral resolution, configurational assignment, and preliminary biological profile of RC752 enantiomers16
Identification and characterization of forced degradation products of sertraline hydrochloride using UPLC, ultra-high-performance liquid Chromatography-Quadrupole-Time of flight mass spectrometry (UHP16
Investigation of novel ATX inhibitor metabolites by UHPLC-orbitrap-MS/MS and molecular docking studies16
Accurate determination for lipidomics based on LC-tandem-MS parameters modeling, prediction, and database: Monitoring the progression of hepatocellular carcinoma15
Ultra-performance liquid chromatography-tandem mass spectrometry for simultaneous determination of 12 anti-tumor drugs in human plasma and its application in therapeutic drug monitoring15
Dual-mode, signal-amplified DNA biosensor for label-free, reliable assay of gestational diabetes mellitus-related miRNA (miR-135a)15
Quantitative study on a simple electrochemical dsDNA-pregabalin biosensor; multi-spectroscopic, molecular docking and modelling studies15
Quality evaluation of Citri Reticulatae Pericarpium by supercritical fluid chromatography with chemical pattern recognition15
Development and validation of a fast UPLC-MS/MS screening method for the detection of 68 psychoactive drugs and metabolites in whole blood and application to post-mortem cases15
Holistic quality evaluation of Callicarpae Formosanae Folium by multi-chromatography-based qualitative and quantitative analysis of polysaccharides and small molecules15
Multidimensional isotope analysis of carbon, hydrogen, and oxygen as a tool for traceability of lactose in drug products15
Guilty by dissociation: Part B: evaluation of Supercritical Fluid Chromatography (SFC-UV) for the analysis of regioisomeric diphenidine-derived Novel Psychoactive Substances (NPS)15
Characterization of in-vivo human metabolites of the oral nucleoside anti-COVID-19 drug VV116 using UHPLC-Orbitrap-MS15
A chemometric model for the quantitative determination of isotopic impurities in d-methylamine hydrochloride by Fourier-transform infrared spectroscopy15
UHPLC-MS/MS-based analysis of 17 nitazenes in human hair for practical forensic casework with simultaneous separation of 6 groups of isomers15
Simultaneous monitoring of multiple attributes of pyrrolobenzodiazepine antibody-drug conjugates by size exclusion chromatography – high resolution mass spectrometry15
Fourier transform infrared spectroscopy, high-performance liquid chromatography with diode array detection, and gas chromatography-mass spectrometry fingerprints combined with chemometrics for compreh15
A multistep approach for exploring quality markers of Shengjiang Xiexin decoction by integrating plasma pharmacochemistry-pharmacokinetics-pharmacology15
Stability of antipsychotic biomarkers for wastewater-based epidemiology15
Investigation of an artificial solution degradant of linagliptin: An undesired linagliptin urea derivative generates in sample preparation of linagliptin tablet treated by sonication in acetonitrile c15
Investigation of metabolic kinetics in different brain regions of awake rats using the [1H-13C]-NMR technique15
Investigation of stereochemical stability of 2-, 3- and 4-chloromethcathinones in various biological matrixes15
A semi-targeted NMR-based chemical profiling of retail samples of Mexican gordolobo15
Rapid screening of hepatotoxic components in Uncariae Ramulus Cum Uncis based on “component-target-pathway” network15
A multi-target QSRR approach to model retention times of small molecules in RPLC15
A serum metabolomics study based on LC-MS: Chemosensitization effects of Rauvolfia vomitoria Afzel. combined with 5- fluorouracil on colorectal cancer mice15
Monolithic and hierarchically porous biochar/cellulose aerogel as adsorbent for microextraction in packed syringe towards trace sulfonamides in water samples prior to UPLC-MS/MS15
Comparison of capillary electrophoresis-based methods for the analytical characterization of purity and stability of in vitro transcribed mRNA15
Economical irregular silica as an effective dispersive solid-phase extraction sorbent for the quantification of calcitriol in soft capsules15
A validated method for detection of cannflavins in hemp extracts15
Editorial Board14
Physicochemical and structural analysis of N-phenylacetyl-L-prolylglycine ethyl ester (Noopept) – An active pharmaceutical ingredient with nootropic activity14
Comparative pharmacokinetic analysis of six major bioactive constituents using UPLC-MS/MS in samples isolated from normal and diabetic nephropathy rats after oral administration of Gushen Jiedu capsul14
Multi-microdialysis analytical system to monitor acetaminophen and its pharmacokinetic interaction with A. bidentata in rat blood, forelimb extensor muscle, brain striatum, and the knee joint cavity14
A selective and accurate liquid chromatography-tandem mass spectrometry method for the quantitation of the novel 5-HT4 receptor partial agonist SUVN-D4010 (Usmarapride) in human plasma and urine14
Editorial Board14
Updating the use of nano-biosensors as promising devices for the diagnosis of coronavirus family members: A systematic review14
Study on tissue distribution, metabolite profiling, and excretion of [14C]-labeled flonoltinib maleate in rats14
Dynamic metabolic profiles for HBeAg seroconversion in chronic hepatitis B (CHB) patients by gas chromatography-mass spectrometry (GC-MS)14
Editorial Board14
Electrochemical and theoretical study on interaction between erlotinib and DNA14
Editorial Board14
Chemical analysis of Chrysosplenium from different species by UPLC-Q exactive orbitrap HRMS and HPLC-DAD14
Simultaneous relative UV response determination of known liquid drug product degradants by NMR spectroscopy14
Oxidative degradation in pharmaceuticals: Mechanism and stabilization of a spray-dried amorphous drug – A case study14
Efficacy evaluation and metabolomics analysis of Huanglian Jiedu decoction in combination with donepezil for Alzheimer's disease treatment14
Editorial Board14
Evaluation of the effect of CYP2D6*3, *4,*10, and *17 polymorphisms on the pharmacokinetic of tamoxifen and its metabolites in patients with hormone-positive breast cancer14
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