OOIR: Observatory of International Research

Papers

(The H4-Index of Biotechnology Advances is 67. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Editorial Board	347
Editorial Board	198
Targeted analysis of metagenomes: divide and conquer	178
Collagen processing with mesoscale aggregates as templates and building blocks	172
Methanol metabolism in synthetic methylotrophic microorganisms	170
New perspectives into Gluconobacter-catalysed biotransformations	165
Anaerobic digestion integrated with microbial electrolysis cell to enhance biogas production and upgrading in situ	164
Advancements of astaxanthin production in Haematococcus pluvialis: Update insight and way forward	153
Evolving perspectives on lutein production from microalgae - A focus on productivity and heterotrophic culture	147
Use of additives to improve collective biogas plant performances: A comprehensive review	137
Biotechnological production and emerging applications of betalains: A review	132
Biotechnological advances in key regulatory genes of phenylpropanoid and terpenoid biosynthesis pathways in Panax ginseng: Current insights and future prospects	130
Decoding microbial interactions: Interaction networks and regulatory strategies for medium-chain fatty acid biosynthesis through anaerobic chain elongation	129
Development of isopentenyl phosphate kinases and their application in terpenoid biosynthesis	127
Opportunities for visual techniques to determine characteristics and limitations of electro-active biofilms	125
Phosphorylated polysaccharides: Applications, natural abundance, and new-to-nature structures generated by chemical and enzymatic functionalisation	124
Chiral helical scaffolds: Unlocking their potential in biomolecular interactions and biomedical applications	124
Think outside the box: 3D bioprinting concepts for biotechnological applications – recent developments and future perspectives	124
Benzylisoquinoline alkaloid production: Moving from crop farming to chemical and biosynthesis	123
Accessing hidden microbial biosynthetic potential from underexplored sources for novel drug discovery	112
Potential for microbial plastic degradation via assimilation of non-carbon moieties in additives	112
Pickering emulsion biocatalysis: Bridging interfacial design with enzymatic reactions	111
Microbial computing: Review and Perspectives	109
Machine learning methods for small data and upstream bioprocessing applications: A comprehensive review	107
Recent advances and perspectives on production of value-added organic acids through metabolic engineering	105

Glycosylation in extracellular vesicles: Isolation, characterization, composition, analysis and clinical applications	103
Editorial Board	99
Biosensors in microalgae: A roadmap for new opportunities in synthetic biology and biotechnology	99
Recent advances in machine learning applications in metabolic engineering	98
Growth-coupled high throughput selection for directed enzyme evolution	97
Biological valorization of lignin to flavonoids	95
Emerging research insights and future perspectives on the advancement of eccDNA: A comprehensive review	92
The path to biotechnological singularity: Current breakthroughs and outlook	92
Methanotrophs as a reservoir for bioactive secondary metabolites: Pitfalls, insights and promises	90
Advances and challenges in enzymatic rubber degradation: Exploring genetic, molecular, and biotechnological aspects	89
Alpha-ketoacid decarboxylases: Diversity, structures, reaction mechanisms, and applications for biomanufacturing of platform chemicals and fuels	89
Enzymatic de novo oligonucleotide synthesis: Emerging techniques and advancements	87
Advances in gene editing-led route for hybrid breeding in crops	85
Elucidation and biosynthesis of tetrahydroisoquinoline alkaloids: Recent advances and prospects	84
Plant cell wall biosynthesis: Immune signaling, genome editing, and physiological implications for biomass valorization	83
Biocatalytic oxyfunctionalization of unsaturated fatty acids to oxygenated chemicals via hydroxy fatty acids	83
Advances in transcription factor-based biosensors for natural product biosynthesis: Optimization, emerging technologies, and future prospects	80
Computational methods for spatial multi-omics integration	79
Droplet microfluidics for single-cell analysis: From improved cell encapsulation and sorting technologies to innovative applications	79
Haloferax and the Haloferacaceae: Potential role in bioindustry	78
Polyhydroxyalkanoates synthesis by halophiles and thermophiles: towards sustainable production of microbial bioplastics	78
Electrode functional microorganisms in bioelectrochemical systems and its regulation: A review	78
Protease engineering: Approaches, tools, and emerging trends	78
Genome-scale metabolic network models for industrial microorganisms metabolic engineering: Current advances and future prospects	77
Polyethylene biodegradation: A multifaceted approach	77
Biotechnological applications of purine and pyrimidine deaminases	77
Advances in bacterial glycoprotein engineering: A critical review of current technologies, emerging challenges, and future directions	76
Emerging advances in glycoengineering of carbohydrates/glycans and their industrial applications	76
Editorial Board	76
Bioinspired nanoplatforms for human-machine interfaces: Recent progress in materials and device applications	76
Problems and corresponding strategies for converting CO2 into value-added products in Cupriavidus necator H16 cell factories	76
Unlocking the bacterial domain for industrial biotechnology applications using universal parts and tools	76
Ex-situ biomethanation for CO2 valorization: State of the art, recent advances, challenges, and future prospective	76
Advances in in vitro cultivation techniques for comprehensive analysis of human gut microbiome	74
From lignocellulosic biomass to single cell oil for sustainable biomanufacturing: Current advances and prospects	73
Optimizing prime editing: Advances in efficiency enhancement	72
Improving recombinant protein production in CHO cells using the CRISPR-Cas system	71
Rutinosidase and other diglycosidases: Rising stars in biotechnology	71
Resource allocation in mammalian systems	70
Loop engineering in enzymes from structure to function: Mechanisms, methodologies, and engineering strategies	70
Engineering oleaginous red yeasts as versatile chassis for the production of oleochemicals and valuable compounds: Current advances and perspectives	70
Strategies for overcoming the limitations of enzymatic carbon dioxide reduction	69
The fungal cure: Harnessing mycelial approach as sustainable green solution for industrial waste treatment	67
Influence of elevated pressure and pressurized fluids on microenvironment and activity of enzymes	67