OOIR: Observatory of International Research

Papers

(The H4-Index of Biotechnology Advances is 67. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Editorial Board	314
Editorial Board	178
Evolving perspectives on lutein production from microalgae - A focus on productivity and heterotrophic culture	168
Use of additives to improve collective biogas plant performances: A comprehensive review	163
Targeted analysis of metagenomes: divide and conquer	152
Decoding microbial interactions: Interaction networks and regulatory strategies for medium-chain fatty acid biosynthesis through anaerobic chain elongation	151
Anaerobic digestion integrated with microbial electrolysis cell to enhance biogas production and upgrading in situ	150
Methanol metabolism in synthetic methylotrophic microorganisms	139
Collagen processing with mesoscale aggregates as templates and building blocks	129
Biotechnological production and emerging applications of betalains: A review	125
Advancements of astaxanthin production in Haematococcus pluvialis: Update insight and way forward	124
Biotechnological advances in key regulatory genes of phenylpropanoid and terpenoid biosynthesis pathways in Panax ginseng: Current insights and future prospects	120
New perspectives into Gluconobacter-catalysed biotransformations	118
Development of isopentenyl phosphate kinases and their application in terpenoid biosynthesis	115
Opportunities for visual techniques to determine characteristics and limitations of electro-active biofilms	113
Benzylisoquinoline alkaloid production: Moving from crop farming to chemical and biosynthesis	112
Pickering emulsion biocatalysis: Bridging interfacial design with enzymatic reactions	110
Potential for microbial plastic degradation via assimilation of non-carbon moieties in additives	110
Machine learning methods for small data and upstream bioprocessing applications: A comprehensive review	108
Accessing hidden microbial biosynthetic potential from underexplored sources for novel drug discovery	107
Recent advances and perspectives on production of value-added organic acids through metabolic engineering	107
Think outside the box: 3D bioprinting concepts for biotechnological applications – recent developments and future perspectives	106
Biosensors in microalgae: A roadmap for new opportunities in synthetic biology and biotechnology	103
Chiral helical scaffolds: Unlocking their potential in biomolecular interactions and biomedical applications	102
Microbial computing: Review and Perspectives	101

Phosphorylated polysaccharides: Applications, natural abundance, and new-to-nature structures generated by chemical and enzymatic functionalisation	100
Glycosylation in extracellular vesicles: Isolation, characterization, composition, analysis and clinical applications	100
Editorial Board	98
Biological valorization of lignin to flavonoids	97
Plant cell wall biosynthesis: Immune signaling, genome editing, and physiological implications for biomass valorization	97
Advances in gene editing-led route for hybrid breeding in crops	92
Droplet microfluidics for single-cell analysis: From improved cell encapsulation and sorting technologies to innovative applications	92
Advances and challenges in enzymatic rubber degradation: Exploring genetic, molecular, and biotechnological aspects	90
Methanotrophs as a reservoir for bioactive secondary metabolites: Pitfalls, insights and promises	89
Emerging research insights and future perspectives on the advancement of eccDNA: A comprehensive review	89
The path to biotechnological singularity: Current breakthroughs and outlook	86
Recent advances in machine learning applications in metabolic engineering	84
Biotechnological applications of purine and pyrimidine deaminases	82
Electrode functional microorganisms in bioelectrochemical systems and its regulation: A review	80
Growth-coupled high throughput selection for directed enzyme evolution	80
Elucidation and biosynthesis of tetrahydroisoquinoline alkaloids: Recent advances and prospects	80
Ex-situ biomethanation for CO2 valorization: State of the art, recent advances, challenges, and future prospective	78
Computational methods for spatial multi-omics integration	78
Haloferax and the Haloferacaceae: Potential role in bioindustry	77
Alpha-ketoacid decarboxylases: Diversity, structures, reaction mechanisms, and applications for biomanufacturing of platform chemicals and fuels	77
Polyethylene biodegradation: A multifaceted approach	76
Protease engineering: Approaches, tools, and emerging trends	75
Advances in transcription factor-based biosensors for natural product biosynthesis: Optimization, emerging technologies, and future prospects	74
Genome-scale metabolic network models for industrial microorganisms metabolic engineering: Current advances and future prospects	74
Polyhydroxyalkanoates synthesis by halophiles and thermophiles: towards sustainable production of microbial bioplastics	73
Advances in bacterial glycoprotein engineering: A critical review of current technologies, emerging challenges, and future directions	73
Biocatalytic oxyfunctionalization of unsaturated fatty acids to oxygenated chemicals via hydroxy fatty acids	73
Improving recombinant protein production in CHO cells using the CRISPR-Cas system	73
Enzymatic de novo oligonucleotide synthesis: Emerging techniques and advancements	73
Bioinspired nanoplatforms for human-machine interfaces: Recent progress in materials and device applications	73
Strategies for overcoming the limitations of enzymatic carbon dioxide reduction	71
Emerging advances in glycoengineering of carbohydrates/glycans and their industrial applications	71
Unlocking the bacterial domain for industrial biotechnology applications using universal parts and tools	70
Research progress of engineering microbial cell factories for pigment production	69
Expanding sugar alcohol industry: Microbial production of sugar alcohols and associated chemocatalytic derivatives	69
Editorial Board	69
Rutinosidase and other diglycosidases: Rising stars in biotechnology	69
Problems and corresponding strategies for converting CO2 into value-added products in Cupriavidus necator H16 cell factories	68
Advances in in vitro cultivation techniques for comprehensive analysis of human gut microbiome	68
Optimizing prime editing: Advances in efficiency enhancement	67
Utilization of gene manipulation system for advancing the biotechnological potential of halophiles: A review	67
Fusarium as a promising fungal genus with potential application in bioremediation for pollutants mitigation: A review	67
Influence of elevated pressure and pressurized fluids on microenvironment and activity of enzymes	67