OOIR: Observatory of International Research

Papers

(The H4-Index of Biotechnology Advances is 64. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
Editorial Board	455
Advancements of astaxanthin production in Haematococcus pluvialis: Update insight and way forward	230
Development of isopentenyl phosphate kinases and their application in terpenoid biosynthesis	219
Halocins, natural antimicrobials of Archaea: Exotic or special or both?	182
Biotechnological production and emerging applications of betalains: A review	174
Evolving perspectives on lutein production from microalgae - A focus on productivity and heterotrophic culture	158
Use of additives to improve collective biogas plant performances: A comprehensive review	154
Computer-aided understanding and engineering of enzymatic selectivity	147
Recent advances in human respiratory epithelium models for drug discovery	141
New perspectives into Gluconobacter-catalysed biotransformations	139
Microbial cell surface engineering for high-level synthesis of bio-products	137
Anaerobic digestion integrated with microbial electrolysis cell to enhance biogas production and upgrading in situ	131
Collagen processing with mesoscale aggregates as templates and building blocks	130
Stabilization of enzymes via immobilization: Multipoint covalent attachment and other stabilization strategies	130
Phosphorylated polysaccharides: Applications, natural abundance, and new-to-nature structures generated by chemical and enzymatic functionalisation	123
Pickering emulsion biocatalysis: Bridging interfacial design with enzymatic reactions	121
Accessing hidden microbial biosynthetic potential from underexplored sources for novel drug discovery	119
Chiral helical scaffolds: Unlocking their potential in biomolecular interactions and biomedical applications	112
Glycosylation in extracellular vesicles: Isolation, characterization, composition, analysis and clinical applications	111
Biosensors in microalgae: A roadmap for new opportunities in synthetic biology and biotechnology	107
Think outside the box: 3D bioprinting concepts for biotechnological applications – recent developments and future perspectives	104
Recent advances and perspectives on production of value-added organic acids through metabolic engineering	103
Opportunities for visual techniques to determine characteristics and limitations of electro-active biofilms	103
Polyethylene biodegradation: A multifaceted approach	102
Alpha-ketoacid decarboxylases: Diversity, structures, reaction mechanisms, and applications for biomanufacturing of platform chemicals and fuels	98

Protease engineering: Approaches, tools, and emerging trends	98
Editorial Board	97
Elucidation and biosynthesis of tetrahydroisoquinoline alkaloids: Recent advances and prospects	96
Biotechnological applications of purine and pyrimidine deaminases	91
Enhancing single-cell bioconversion efficiency by harnessing nanosecond pulsed electric field processing	91
Advances in gene editing-led route for hybrid breeding in crops	90
Methanotrophs as a reservoir for bioactive secondary metabolites: Pitfalls, insights and promises	90
Charting the landscape of RNA polymerases to unleash their potential in strain improvement	89
Biocatalytic oxyfunctionalization of unsaturated fatty acids to oxygenated chemicals via hydroxy fatty acids	86
Growth-coupled high throughput selection for directed enzyme evolution	86
Enzymatic de novo oligonucleotide synthesis: Emerging techniques and advancements	85
Unlocking the secret of lignin-enzyme interactions: Recent advances in developing state-of-the-art analytical techniques	84
Microbial starch debranching enzymes: Developments and applications	84
Genome-scale metabolic network models for industrial microorganisms metabolic engineering: Current advances and future prospects	82
From lignocellulose to plastics: Knowledge transfer on the degradation approaches by fungi	80
Recent advances in machine learning applications in metabolic engineering	78
Polyhydroxyalkanoates synthesis by halophiles and thermophiles: towards sustainable production of microbial bioplastics	78
Electrode functional microorganisms in bioelectrochemical systems and its regulation: A review	77
Biological valorization of lignin to flavonoids	77
Ex-situ biomethanation for CO2 valorization: State of the art, recent advances, challenges, and future prospective	77
Emerging advances in glycoengineering of carbohydrates/glycans and their industrial applications	75
Advances in bacterial glycoprotein engineering: A critical review of current technologies, emerging challenges, and future directions	75
Rutinosidase and other diglycosidases: Rising stars in biotechnology	74
Bioinspired nanoplatforms for human-machine interfaces: Recent progress in materials and device applications	73
Improving recombinant protein production in CHO cells using the CRISPR-Cas system	73
Advances in in vitro cultivation techniques for comprehensive analysis of human gut microbiome	72
Recent advances in research for potential utilization of unexplored lichen metabolites	72
Guidelines toward ecologically-informed bioprospecting for microbial plastic degradation	72
Utilization of gene manipulation system for advancing the biotechnological potential of halophiles: A review	71
Expanding sugar alcohol industry: Microbial production of sugar alcohols and associated chemocatalytic derivatives	70
Strategies for overcoming the limitations of enzymatic carbon dioxide reduction	70
Influence of elevated pressure and pressurized fluids on microenvironment and activity of enzymes	69
From lignocellulosic biomass to single cell oil for sustainable biomanufacturing: Current advances and prospects	68
Fusarium as a promising fungal genus with potential application in bioremediation for pollutants mitigation: A review	67
Unlocking the bacterial domain for industrial biotechnology applications using universal parts and tools	65
Problems and corresponding strategies for converting CO2 into value-added products in Cupriavidus necator H16 cell factories	64
Stress response in Rhodococcus strains	64
Engineering oleaginous red yeasts as versatile chassis for the production of oleochemicals and valuable compounds: Current advances and perspectives	64
Research progress of engineering microbial cell factories for pigment production	64