OOIR: Observatory of International Research

Papers

(The H4-Index of Biotechnology Advances is 67. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Editorial Board	469
Targeted analysis of metagenomes: divide and conquer	249
Collagen processing with mesoscale aggregates as templates and building blocks	247
Anaerobic digestion integrated with microbial electrolysis cell to enhance biogas production and upgrading in situ	187
New perspectives into Gluconobacter-catalysed biotransformations	184
Microbial cell surface engineering for high-level synthesis of bio-products	166
Computer-aided understanding and engineering of enzymatic selectivity	162
Biotechnological production and emerging applications of betalains: A review	159
Evolving perspectives on lutein production from microalgae - A focus on productivity and heterotrophic culture	157
Advancements of astaxanthin production in Haematococcus pluvialis: Update insight and way forward	150
Halocins, natural antimicrobials of Archaea: Exotic or special or both?	147
Development of isopentenyl phosphate kinases and their application in terpenoid biosynthesis	143
Use of additives to improve collective biogas plant performances: A comprehensive review	142
Methanol metabolism in synthetic methylotrophic microorganisms	134
Stabilization of enzymes via immobilization: Multipoint covalent attachment and other stabilization strategies	129
Recent advances in human respiratory epithelium models for drug discovery	128
Chiral helical scaffolds: Unlocking their potential in biomolecular interactions and biomedical applications	124
Think outside the box: 3D bioprinting concepts for biotechnological applications – recent developments and future perspectives	123
Biosensors in microalgae: A roadmap for new opportunities in synthetic biology and biotechnology	118
Glycosylation in extracellular vesicles: Isolation, characterization, composition, analysis and clinical applications	117
Accessing hidden microbial biosynthetic potential from underexplored sources for novel drug discovery	110
Opportunities for visual techniques to determine characteristics and limitations of electro-active biofilms	110
Potential for microbial plastic degradation via assimilation of non-carbon moieties in additives	106
Phosphorylated polysaccharides: Applications, natural abundance, and new-to-nature structures generated by chemical and enzymatic functionalisation	105
Pickering emulsion biocatalysis: Bridging interfacial design with enzymatic reactions	105

Recent advances and perspectives on production of value-added organic acids through metabolic engineering	104
Alpha-ketoacid decarboxylases: Diversity, structures, reaction mechanisms, and applications for biomanufacturing of platform chemicals and fuels	103
The path to biotechnological singularity: Current breakthroughs and outlook	100
Editorial Board	97
Emerging research insights and future perspectives on the advancement of eccDNA: A comprehensive review	97
Editorial Board	96
Biological valorization of lignin to flavonoids	93
Enhancing single-cell bioconversion efficiency by harnessing nanosecond pulsed electric field processing	93
Advances in gene editing-led route for hybrid breeding in crops	92
Unlocking the secret of lignin-enzyme interactions: Recent advances in developing state-of-the-art analytical techniques	92
Charting the landscape of RNA polymerases to unleash their potential in strain improvement	90
Biotechnological applications of purine and pyrimidine deaminases	90
Elucidation and biosynthesis of tetrahydroisoquinoline alkaloids: Recent advances and prospects	87
Growth-coupled high throughput selection for directed enzyme evolution	87
Polyethylene biodegradation: A multifaceted approach	87
Genome-scale metabolic network models for industrial microorganisms metabolic engineering: Current advances and future prospects	86
Methanotrophs as a reservoir for bioactive secondary metabolites: Pitfalls, insights and promises	86
Ex-situ biomethanation for CO2 valorization: State of the art, recent advances, challenges, and future prospective	83
Polyhydroxyalkanoates synthesis by halophiles and thermophiles: towards sustainable production of microbial bioplastics	83
Haloferax and the Haloferacaceae: Potential role in bioindustry	81
Protease engineering: Approaches, tools, and emerging trends	81
Biocatalytic oxyfunctionalization of unsaturated fatty acids to oxygenated chemicals via hydroxy fatty acids	80
Recent advances in machine learning applications in metabolic engineering	80
Electrode functional microorganisms in bioelectrochemical systems and its regulation: A review	79
Advances in bacterial glycoprotein engineering: A critical review of current technologies, emerging challenges, and future directions	78
Enzymatic de novo oligonucleotide synthesis: Emerging techniques and advancements	78
Advances in in vitro cultivation techniques for comprehensive analysis of human gut microbiome	77
Strategies for overcoming the limitations of enzymatic carbon dioxide reduction	76
Guidelines toward ecologically-informed bioprospecting for microbial plastic degradation	75
Emerging advances in glycoengineering of carbohydrates/glycans and their industrial applications	75
Unlocking the bacterial domain for industrial biotechnology applications using universal parts and tools	75
Recent advances in research for potential utilization of unexplored lichen metabolites	75
Influence of elevated pressure and pressurized fluids on microenvironment and activity of enzymes	74
Fusarium as a promising fungal genus with potential application in bioremediation for pollutants mitigation: A review	74
Stress response in Rhodococcus strains	72
Bioinspired nanoplatforms for human-machine interfaces: Recent progress in materials and device applications	71
From lignocellulosic biomass to single cell oil for sustainable biomanufacturing: Current advances and prospects	70
Engineering oleaginous red yeasts as versatile chassis for the production of oleochemicals and valuable compounds: Current advances and perspectives	69
Research progress of engineering microbial cell factories for pigment production	68
Improving recombinant protein production in CHO cells using the CRISPR-Cas system	68
Resource allocation in mammalian systems	68
Utilization of gene manipulation system for advancing the biotechnological potential of halophiles: A review	67
Rutinosidase and other diglycosidases: Rising stars in biotechnology	67
Problems and corresponding strategies for converting CO2 into value-added products in Cupriavidus necator H16 cell factories	67