Cancer Investigation

Article	Citations
Outcomes of Oral and Oropharyngeal Squamous Cell Carcinoma Related to Healthcare Coverage: A Retrospective Cohort Study in Brazil	61
Clinical Trial Access in Low- and Middle-Income Countries: A Case Study on India	58
Three Third-Generation Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancer: Similarities and Differences	21
Artificial Intelligence in Cancer Clinical Research: V. What We Have Learned About Human Intelligence from Artificial Intelligence	21
A DNA Damage Response Related Signature to Predict Prognosis in Patients with Acute Myeloid Leukemia	19
Suitability of Metastatic Lung Tumors for Stereotactic Body Radiotherapy	16
The Inflation in Oncology Publications and Journals: A Vicious Cycle That Needs Immediate Attention	16
Conceptualization of Breast Cancer and Attitudes toward Breast Cancer Screening: A Qualitative Study on Iranian and Australian Women	16
Weather-Related Factors and Patient-Reported Outcomes (PROs) in Cancer Patients: Results from the ExPRO Study	14
Fooled by Randomness. The Misleading Effect of Treatment Crossover in Randomized Trials of Therapies with Marginal Treatment Benefit	14
LDHB Mediates Histone Lactylation to Activate PD-L1 and Promote Ovarian Cancer Immune Escape	12
Telomere Shortening of Barrett’s Esophagus and Esophageal Adenocarcinoma in Japanese Patients	12
In-Silico Analysis of Differentially Expressed Genes and Their Regulating microRNA Involved in Lymph Node Metastasis in Invasive Breast Carcinoma	12
Effect of Androgen–Androgen Receptor Directed Therapy on COVID-19 Outcome in Prostate Cancer Patients	11
Assessment of Swallowing Function in Patients with Head and Neck Squamous Cell Carcinoma in High vs. Low Dose Cisplatin	11
Perception, Cognition and Thought: Part V Entropy, the Arrow of Time and the Present	11
Recurrence Patterns and Clinical Management after a Positive Sentinel Node Biopsy in Melanoma Patients	11
Variation of Plasma Damage-Associated Molecular Patterns in Patients with Advanced Solid Tumors after Standard of Care Systemic Treatment	11
Radiation Oncologists’ Views on Adjuvant Radiotherapy for Early-Stage Breast Cancer in the Elderly: Comparisons between Japan and the United States	11
Management of Non-Small Cell Lung Cancer: Updates from the European Lung Cancer Congress 2022	10
Impact of COVID-19 on the Children with Cancer in Six Pediatric Oncology Units (POUs) of Pakistan- A Multi-Center Study	10
Breaking Bad News in Cancer Patients: Voicing the Training Requirement	10
Use of Antiperspirant Products and Risk of Breast Cancer: A Meta-Analysis of Case-Control Studies	10
Outcomes of Patients with COVID-19 from a Specialized Cancer Care Emergency Room	10
The Role of Hematological Inflammatory Biomarkers in the Diagnosis of Lung Cancer and in Predicting TNM Stage	10

Where the Sidewalk Ends: Parenting as a Trainee during COVID-19	10
The Landscape and Prognosis of Microsatellite Stable (MSS) Esophageal, Gastro-Esophageal Junction and Gastric Adenocarcinomas with High Tumor Mutation Burden (TMB)	9
Transforming Skin Cancer Diagnosis: A Deep Learning Approach with the Ham10000 Dataset	9
X-Linked Tumor Suppressor Genes Act as Presumed Contributors in the Sex Chromosome-Autosome Crosstalk in Cancers	9
Racial Diversity and Reporting in United States Food and Drug Administration Registration Trials for Thoracic Malignancies from 2006 to 2020	9
Impact of Radiation Therapy on Biological Parameters in Cancer Patients: Sub-analysis from the RIT Prospective Epidemiological Study	9
Adverse Events Induced by Nivolumab Plus Ipilimumab vs. Nivolumab Monotherapy among Cancer Patients: A Systematic Review and Meta-Analysis	9
Surgical Trauma-induced CCL2 Upregulation Mediates Lung Cancer Progression by Promoting Treg Recruitment in Mice and Patients	8
Engineering Novel CD19/CD22 Dual-Target CAR-T Cells for Improved Anti-Tumor Activity	8
Therapeutic Perspective of Temozolomide Resistance in Glioblastoma Treatment	8
Correlation Between Vascular Endothelial Growth Factor and Long-Term Occurrence of HCV-Related Hepatocellular Carcinoma After Treatment with Direct-Acting Antivirals	8
LncRNA ENSG00000254615 Modulates Proliferation and 5-FU Resistance by Regulating p21 and Cyclin D1 in Colorectal Cancer	8
Quantitative Multiplex Immunofluorescence Evaluation of the Tumor Microenvironment in Pretreatment Tumors of Patients with Metastatic Breast Cancer and Serous Ovarian Carcinoma Treated with Liposomal	8
Immunohistochemical Analysis of Lung Adenocarcinoma in Russian Mayak Nuclear Workers	7
Construction and Validation of a Novel T/NK-Cell Prognostic Signature for Pancreatic Cancer Based on Single-Cell RNA Sequencing	7
Mechanisms and Molecular Targets of Artemisinin in Cancer Treatment	7
Inhibition of BRD4 Suppresses the Growth of Esophageal Squamous Cell Carcinoma	7
The Nature, Origin, and Evolution of Life: Part V Bringing It Together: Concepts, Constraints, and Closure	7
Poorly Controlled Diabetes Mellitus Increases the Risk of Deaths and Castration-Resistance in Locally Advanced Prostate Cancer Patients	7
Enrollment Trends Among Patients with Melanoma Brain Metastasis in Active Clinical Trials	7
Development of a Novel Prognostic Model for Esophageal Squamous Cell Carcinoma: Insights into Immune Cell Interactions and Drug Sensitivity	6
Resilience, Social Support, and Anxious Preoccupation in Patients with Advanced Cancer during COVID-19 Pandemic	6
Multicenter Study of Antibody Seroprevalence against COVID-19 in Patients Presenting to Iranian Cancer Centers after One Year of the COVID-19 Pandemic	6
Mesothelin is Commonly Expressed in Pancreatic Adenocarcinoma but Unrelated to Cancer Aggressiveness	6
Metagenomic Analysis of Biliary Microbial Flora in Patients with Gallbladder Cancer or Gallstones-Associated Chronic Cholecystitis	6
Correction	6
Predictive Modeling of Long-Term Prognosis After Resection in Typical Pulmonary Carcinoid: A Machine Learning Perspective	6
Optimizing Diagnostic Tools & Outcomes Evaluation for t (9;22)-Positive Leukemias in Pediatric Low Middle-Income Country (LMIC) Patients	6
Chemotherapy Primary Dose Reduction in Older Cancer Patients: A Retrospective Cohort	6
Dose-Dense Docetaxel-Cyclophosphamide and Epirubicin-Cisplatin(ddDCEP): Analysis of an Alternative Platinum-Containing Regimen in 116 Patients with Early Triple Negative Breast Cancer	6
Correction	6
Normal Absolute Monocyte Count in Combination with Normal/High Absolute Lymphocyte Count at the Time of Relapse is Associated with Improved Survival in Patients with Early Relapsed Acute Myeloid Leuke	6
Elevated Vitamin B12, Risk of Cancer, and Mortality: A Systematic Review	6
Identification of a Novel Pyroptosis-Related Gene Signature for Predicting Prognosis in Bladder Cancer	5
Gender, Bladder Cancer Healthcare and Burden of COVID-19	5
Perceptions of COVID-19 Vaccination in Patients with Genitourinary Cancers: Correspondence	5
Does Aspirin Use Reduce the Risk for Ovarian Cancer?	5
COVID-19 Outbreak Impact on Cancer Multidisciplinary Team Meetings. A Multicenter French Experience	5
The Use of Modified Surrogate End Points in Cancer Clinical Trials	5
Utility Values in Colorectal Cancer Patients Treated with Chemotherapy	5
Pheochromocytoma with Acute Non-cardiac Pulmonary Edema: A Report of One Case and the Review of Literature	5
Efficacy and Safety of Trastuzumab Emtansine in Her2 Positive Metastatic Breast Cancer: Real-World Experience	5
Perceptions of COVID-19 Vaccination in Patients with Genitourinary Cancers: A Survey Study	5
NGS-based Tissue-Blood TMB Comparison and Blood-TMB Monitoring in Stage-III Non-Small Cell Lung Cancer Treated with Concurrent Chemoradiotherapy	5
“Anemia and Response to Neoadjuvant Chemotherapy in Breast Cancer Patients”	4
Real World Presentation and Treatment Outcomes with a Predominant Induction Chemotherapy Based Approach in Nasopharyngeal Carcinoma: A Sixteen Year Report from a Teaching Hospital in India	4
A Nomogram for Predicting Survival in Advanced Non-Small-Cell Lung Carcinoma Patients: A Population-Based Study	4
Plasma D-Dimer and Fibrinogen Levels Correlates with Tumor Size and Disease Progression in Nigerian Breast Cancer Patients	4
Once-a-Week Ablative Radiotherapy as Replacement of Prolonged Fractionation in Frail Patients: Feasibility and Toxicity Results	4
Evaluation of the Efficacy of Postoperative Adjuvant Therapy for HER2-Positive Ductal Carcinoma in Situ with Microinvasion	4

Geospatial Disparities in Access to Proton Therapy in the Continental United States	4
Allostatic Load, Mobility Disability, and Viral Effects in Cancer: A Structural Equation Model	4
Identification of the Integrated Prognostic Signature Associated with Immuno-relevant Genes and Long Non-coding RNAs in Acute Myeloid Leukemia	4
Fear of Cancer Recurrence and COVID-19 Anxiety Among Cancer Survivors: A Cross-Sectional Study in Southeast Iran	4
Long Non-Coding RNA H19 Expression Correlates with Autophagy Process in Adrenocortical Carcinoma	4
Growth Differentiation Factor-15 as a Candidate Biomarker in Gynecologic Malignancies: A Meta-analysis	4
Tumor Properties Mediate the Relationship between Peripheral Blood Monocytes and Tumor-Associated Macrophages in Breast Cancer	4
Metastasis to Breast from Extramammary Solid Tumors and Lymphomas: A 20-Year Population-Based Study	4
Assessing SPP1/Osteopontin (OPN) Splice Variants and Their Association to Nonmelanoma Skin Cancer by Absolute Quantification: Identification of OPN-5 Subvariants and Their Protein Coding Potential	4
Routine Skin Cancer Screening: Balance between Overdiagnosis and Prevention	4
Accuracy of the ‘CUT’ Score for Assessing Malignancy in Bethesda 3 and 4 Thyroid Nodules in North American Population: A Retrospective Study	4
Application in Gene Editing in Ovarian Cancer Therapy	4
Inhibitory Effects of Bilirubin on Colonization and Migration of A431 and SK-MEL-3 Skin Cancer Cells Compared with Human Dermal Fibroblasts (HDF)	4
Glucose Metabolism and Glucose Transporters in Head and Neck Squamous Cell Carcinoma	4
Impact of the Multidisciplinary Cancer Team on the Diagnostic and Therapeutic Care Pathway of Early Breast Cancer Patients and Perception of Team Members: The Experience of a Cancer Centre in Italy	4
The Expression and Survival Significance of Glucose Transporter-1 in Pancreatic Cancer: Meta-Analysis, Bioinformatics Analysis and Retrospective Study	3
The Journey of Resveratrol from Vineyards to Clinics	3
Efficacy and Safety of First-Line Platinum-Based Doublet Chemotherapy in Advanced Primary Pulmonary Salivary Gland Tumors (PSGTs)	3
Comorbidity in Small Cell Lung Cancer: Prognostic Impacts of Hypertension/Coronary Artery Disease, Diabetes Mellitus, and Chronic Obstructive Pulmonary Disease	3
Predictive Efficacy of Circulating Tumor Cells in First Drainage Vein Blood from Patients with Colorectal Cancer Liver Metastasis	3
Development and Validation of a Nomogram for Prognosis Prediction in Patients with Synchronous Primary Thyroid and Breast Cancer Based on SEER Database	3
A Comprehensive Insight into Apoptosis: Molecular Mechanisms, Signaling Pathways, and Modulating Therapeutics	3
Clinical validation of a ctDNA-Based Assay for Multi-Cancer Detection: An Interim Report from a Vietnamese Longitudinal Prospective Cohort Study of 2795 Participants	3
Less is More? First Impressions From COSMIC-313	3
Genomic Alterations of Signaling and DNA Damage Repair Pathways in Non-Muscle Invasive Bladder Cancer	3
Predictive Value of Preoperative Neutrophil-to-Lymphocyte Ratio in Patients with Hepatocellular Carcinoma after Transarterial Chemoembolization Combined With Radiofrequency Ablation	3
A Systematic Review of the Treatment Outcomes among Prostate Cancer Patients in Africa	3
Beyond the Horizon: A Cutting-Edge Review of the Latest Checkpoint Inhibitors in Cancer Treatment	3
Flamingo Search Sailfish Optimizer Based SqueezeNet for Detection of Breast Cancer Using MRI Images	3
PARP Inhibitors Rising as an Epoch-Making Strategy in First-Line Maintenance Therapy of Ovarian Cancer: A Systematic Review and Meta-Analysis	3
Clinical Analysis of the Efficacy and Safety of Different Neoadjuvant Strategies in the Treatment of Locally Advanced Rectal Cancer	3
Ultra-Deep Sequencing of Plasma-Circulating DNA for the Detection of Tumor- Derived Mutations in Patients with Nonmetastatic Colorectal Cancer	3
Epidemiological Assessment of Oral Cancer Burden in Pakistan	3
Decision Aids for Decision Making about Locally Advance Breast Cancer: A Systematic Review	3
TTYH3 Promotes Cervical Cancer Progression by Activating the Wnt/ β -Catenin Signaling Pathway	3
Artificial Intelligence in Cancer Clinical Research: I. Introduction	3
The Effect of Hypnosis on the Intensity of Pain and Anxiety in Cancer Patients: A Systematic Review of Controlled Experimental Trials	3
Bioinformatics Identification and Validation of Aging‑Related Molecular Subtype and Prognostic Signature in Sarcoma	2
Current Use and Limitations of Cultured High-Grade Meningioma Cells in Neuro-Oncological Research – In Response to: “Caution Using Meningioma Cell Lines as Tumor Models”	2
The Relationship Between Body Image and Meaning of Life Among Women with Breast Cancer in Kerman, Iran	2
The Democratization of Hematology-Oncology Medical Education during the COVID-19 Pandemic	2
Veliparib‑Induced Toxicity in Cancer Patients: A Systematic Review and Meta‑Analysis	2
Randomized, Double-Blind, Placebo-Controlled Clinical Trial of Concurrent Use of Crocin During Chemoradiation for Esophageal Squamous Cell Carcinoma	2
In Vitro and In Vivo Synergistic Antitumor Activity of Albumin-Coated Oleic Acid-Loaded Liposomes toward Hepatocellular Carcinoma	2
Jurkat T Cells are Immunophenotypically Distinct from T-Cell Acute Lymphoblastic Leukemia Cells Due to High-Level Surface Expression of CD5	2
Risk Model Development and Validation in Clinical Oncology: Lessons Learned	2
Outcomes of Cancer Patients with COVID-19: The Virginia Commonwealth University Experience	2
Postoperative Radiotherapy for Cutaneous Melanoma in Patients at High Risk of Local-Regional Recurrence after Surgery Alone	2
Primary Pleuropulmonary Synovial Sarcoma: Report of Two Cases and a Comprehensive Review of the Literature	2
Long Non-Coding RNA and Chemoresistance in Bladder Cancer – A Mini Review	2
Cognitive Dysfunction in Non-CNS Metastatic Cancer: Comparing Brain Metastasis, Non-CNS Metastasis, and Healthy Controls	2
The Prognostic Value of ADAMTS8 and Its Role as a Tumor Suppressor in Breast Cancer	2
Sucrose Nonfermenting-Related Kinase Expression Is Related to a Metabolic Switch in Ovarian Cancer Cells That Results in Increased Fatty Acid Oxidation	2
Trends and Projections of Stomach Cancer Incidence in Hong Kong: A Population-Based Study	2
The Impact of Prophylactic Post-Chemotherapy G-CSF on the Relapse Rates in Patients with Acute Myeloid Leukemia: A Meta-Analysis	2
Efficacy and Safety of Additional S-1 Chemotherapy to S-1 Plus Oxaliplatin Regimen Chemotherapy for Stage III Gastric Carcinoma after Radical Resection	2
Advance of Circulating Tumor Cells in the Prognosis and Management of Endometrial Cancer	2
Identification of Immune-Related Gene Pair Signature to Predict Prognosis of Diffuse Large B-Cell Lymphoma Based on Bioinformatics Analyses	2
Anxiety, Depression, and Coping Strategies during Chemotherapy Treatment: A Comparison of Older and Younger Adults with Advanced Cancer in Brazil	2
Clinical Characteristics and Outcomes of COVID-19 in 1294 New Cancer Patients: Single-Center, Prospective Cohort Study from Iran	2
Risk and Prognosis of Second Primary Cancers among Ovarian Cancer Patients, Based on SEER Database	2
Drug Repurposing Analysis for Colorectal Cancer through Network Medicine Framework: Novel Candidate Drugs and Small Molecules	2
IRF1 Inhibits Autophagy-Mediated Proliferation of Colorectal Cancer via Targeting ATG13	2
Gustative Roussy Immune Score is a Predictor for Major Pathological Response in Rectal Cancer: A Result from the Preoperative Intraarterial Chemoembolization Combined with Radiotherapy (PCAR) Study	2
Platinum-Pemetrexed Chemotherapy for Recurrent Ovarian Cancer (ROC): A Single Center Experience	1
Webinar as an Informational Resource on Trastuzumab Biosimilars: Planning, Promotion, Execution, and Evaluation	1
Approaches for Head and Neck Cancer Research – Current Status and the Way Forward	1
Integrative Analysis Developing and Validating Potential Candidate Biomarkers for Cancer Stemness Features of Pan-Renal Cell Carcinoma	1
Determinants of Post-Traumatic Growth and Quality of Life in Ghanaian Breast Cancer Survivors	1
The Big Data Paradox in Clinical Practice	1
Role of Interleukin-10 Promoter Polymorphisms in Oral Cancer Susceptibility: A Meta-Analysis	1
Tumoral Overexpression of Hepcidin is Associated with Poor Prognosis of Patients with Clear Cell Renal Cell Carcinoma	1
Perception, Cognition and Thought: Part II Symbolic Processing and Language	1
Single Nucleotide Polymorphisms Associated with Prostate Cancer Progression: A Systematic Review	1
Perineural Invasion as a Prognostic Factor in Laryngeal Squamous Cell Cancer: A Matched-Pair Survival Analysis	1
Comparative Analysis of miRNA and EMT Markers in Metastatic Colorectal Cancer	1
Efficacy and Safety of RET-Specific Kinase Inhibitors in RET-Altered Cancers: A Systematic Review	1
Prognostic Effects of Sarcopenia on Patients with Bladder Cancer: A Systematic Review and Meta-Analysis	1
The Impact of Sorafenib in Combination with Intermittent Hepatic Arterial Infusion Chemotherapy for Unresectable Hepatocellular Carcinoma with Major Vascular Invasion	1
Gain of Chromosome 5q Predicts a Favorable Prognosis in Localized Renal Cell Carcinoma	1

Suspension of Oncology Randomized Clinical Trials during the COVID-19 Pandemic: A Cross-Sectional Evaluation of COVID-Related Suspensions	1
Comparative Analysis of the Chemotherapy-Related Cognitive Impairments in Patients with Breast Cancer: A Community-Based Research	1
Clinical Validation of Local Versus Commercial Genomic Testing in Cancer: A Comparison of Tissue and Plasma Concordance	1
Dynamic Changes of Peripheral NK Cells Predict Outcome in Patients with PD-L1 Positive Non-small-cell Lung Cancer Undergoing Immune Checkpoint Inhibitors as Second-line Therapy	1
Correction	1
Correlation of the Grade Group of Prostate Cancer according to the International Society of Urological Pathology (Isup) 2014 Classification between Prostate Biopsy and Radical Prostatectomy Specimens	1
The Prevalence of Polypharmacy and Potential Drug–Drug Interactions among Iranian Cancer Patients: Which Patients were at Risk?	1
A Mechanistic Review of Methotrexate and Celecoxib as a Potential Metronomic Chemotherapy for Oral Squamous Cell Carcinoma	1
Immune-related Liver Injury is a Poor Prognostic Factor in Patients with Nonsmall Cell Lung Cancer Treated with Immune Checkpoint Inhibitors	1
Perception, Cognition and Thought: Part I Nature, Evolution and Development of Conceptual and Symbolic Processes	1
Tumor Differentiation as a Prognostic Marker in Clinically Staged T1bN0 Esophageal Adenocarcinoma	1
The Nature, Origin, and Evolution of Life: Part IV Cellular Differentiation and the Emergence of Multicellular Life	1
Efficacy of Adjuvant First-Generation TKIs versus Chemotherapy in Patients with Completely Resected EGFR-Mutant Non-Small Cell Lung Cancer: A Meta-Analysis	1
A Bioinformatic Analysis of Gut Microbiota Related with Immune Cell Infiltration in Colorectal Cancer	1
Artificial Intelligence and Cancer Clinical Research: III Risk Prediction Models for Febrile Neutropenia in Patients Receiving Cancer Chemotherapy	1
Magnetic Resonance Imaging Guided Prostate Biopsy in Patients with ≥ One Negative Systematic Transrectal Ultrasound-Guided Biopsy: A Systemic Review and Meta-Analysis	1
Real-World Evidence Shows Clinicians Appropriately Use the Prognostic 40-Gene Expression Profile (40-GEP) Test for High-Risk Cutaneous Squamous Cell Carcinoma (cSCC) Patients	1
Chemotherapy-Induced Oral Complications and Prophylaxis Strategies	1
Identification of Chemo and Radio-Resistant Sub-Population of Stem Cells in Human Cervical Cancer HeLa Cells	1
Pathology Reports: Discrepancy Patterns of Second Opinions in a Referral Cancer Center	1
Tertiary Lymphoid Structures, Immune Response, and Prognostic Relevance in Non-Small Cell Lung Cancer	1
Ethical Principles in the Analysis of Prostate Cancer Diagnostics	1
Artificial intelligence in Cancer Clinical Research: IV. Inherent Limitations of Artificial Intelligence	1
PD-1/PD-L1 Inhibitors Monotherapy for the Treatment of Endometrial Cancer: Meta-Analysis and Systematic Review	1
Perception, Cognition and Thought: Part IV Consciousness, Awareness, and “I”	1
A Review on Emerging Techniques for Diagnosis of Colorectal Cancer	1
Elevated Expression of LGR5 and WNT Signaling Factors in Neuroblastoma Cells With Acquired Drug Resistance	1
Perception, Cognition and Thought: Part III: Reasoning, Judgement and Decision-Making	1
Real-World Incidence and Management of Immune-Related Adverse Events from Immune Checkpoint Inhibitors: Retrospective Claims-Based Analysis	1
Characteristics of Invasive Cribriform Carcinoma	1
The Sledgehammer in Precision Medicine: Dexamethasone and Immunotherapeutic Treatment of Glioma	1