OOIR: Observatory of International Research

Papers

(The TQCC of Critical Reviews in Biotechnology is 19. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Elucidation of transfer RNAs as stress regulating agents and the experimental strategies to conceive the functional role of tRNA-derived fragments in plants	139
New strategies to study in depth the metabolic mechanism of astaxanthin biosynthesis in Phaffia rhodozyma	130
Strategies for modulating transglycosylation activity, substrate specificity, and product polymerization degree of engineered transglycosylases	118
Chassis engineering for high light tolerance in microalgae and cyanobacteria	112
Wastewater-borne viruses and bacteria, surveillance and biosensors at the interface of academia and field deployment	85
D-allulose 3-epimerase for low-calorie D-allulose synthesis: microbial production, characterization, and applications	78
Recent advancements in CRISPR-Cas toolbox for imaging applications	74
A comprehensive review on tissue culture studies and secondary metabolite production in Bacopa monnieri L. Pennell: a nootropic plant	73
Plant lipid phosphate phosphatases: current advances and future outlooks	63
Microbial torularhodin – a comprehensive review	57
Air biofilters for a mixture of organic gaseous pollutants: an approach for industrial applications	57
Amplification-free nucleic acids detection with next-generation CRISPR/dx systems	56
Recent advances in the production of recombinant factor IX: bioprocessing and cell engineering	54
Advances in the development of phage-mediated cyanobacterial cell lysis	53
Algae: the game-changers in biohydrogen sector	52
Nanobiosensors and their role in detection of adulterants and contaminants in food products	50
The revolution of PDMS microfluidics in cellular biology	50
Insight into recent advances in microalgae biogranulation in wastewater treatment	49
Biotechnological application of Aureobasidium spp. as a promising chassis for biosynthesis of ornithine-urea cycle-derived bioproducts	49
Pilot scale polyhydroxyalkanoates biopolymer production using pure cultures: current status and future opportunities	45
Electrospun wound dressings with antibacterial function: a critical review of plant extract and essential oil incorporation	44
Evidence and opportunities for developing non-transgenic genome edited crops using site-directed nuclease 1 approach	43
Developed and emerging 1,4-butanediol commercial production strategies: forecasting the current status and future possibility	41
Atlas of the microbial degradation of fluorinated pesticides	40
Bioreactor configurations for adventitious root culture: recent advances toward the commercial production of specialized metabolites	38

Microbial cell factories using Paenibacillus : status and perspectives	37
Structure-based rational design of hydroxysteroid dehydrogenases for improving and diversifying steroid synthesis	37
Production of L-serine and its derivative L-cysteine from renewable feedstocks using Corynebacterium glutamicum : advances and perspectives	36
Catalytic mechanisms underlying fungal fatty acid desaturases activities	36
Application of biochar on soil bioelectrochemical remediation: behind roles, progress, and potential	36
Liamocins biosynthesis, its regulation in Aureobasidium spp., and their bioactivities	35
Membrane bioreactors for syngas permeation and fermentation	35
Unveiling the potential of dendrobine: insights into bioproduction, bioactivities, safety, circular economy, and future prospects	35
Ultrasonic processing: effects on the physicochemical and microbiological aspects of dairy products	34
Plant phospholipase D: novel structure, regulatory mechanism, and multifaceted functions with biotechnological application	34
Insights into organic loading rates of anaerobic digestion for biogas production: a review	33
Photo-assisted microbial fuel cell systems: critical review of scientific rationale and recent advances in system development	33
Co-culturing microbial consortia: approaches for applications in biomanufacturing and bioprocessing	32
Overview of resveratrol properties, applications, and advances in microbial precision fermentation	32
Enzyme hybrid nanoflowers and enzyme@metal–organic frameworks composites: fascinating hybrid nanobiocatalysts	32
Sustainability of biodegradable plastics: a review on social, economic, and environmental factors	31
Colors of life: a review on fungal pigments	31
Yarrowia lipolytica as a biorefinery platform for effluents and solid wastes valorization – challenges and opportunities	30
Molecular modification and biotechnological applications of microbial aspartic proteases	30
Sustainable utilization of fruit and vegetable waste bioresources for bioplastics production	30
Exploring future applications of the apiculate yeast Hanseniaspora	30
Research progress on the application of cell-free synthesis systems for enzymatic processes	30
Biomolecules of mushroom: a recipe of human wellness	30
Recent updates on green synthesis of lignin nanoparticle and its potential applications in modern biotechnology	30
Smart reprograming of plants against salinity stress using modern biotechnological tools	29
Airborne microbes: sampling, detection, and inactivation	28
It comes from the sea: macroalgae-derived bioactive compounds with anti-cancer potential	28
Value-added biotransformation of agricultural byproducts by cellulolytic fungi: a review	27
Utilizing CO ₂ in industrial off-gas for microalgae cultivation: considerations and solutions	27
Applications of synthetic yeast consortia for the production of native and non-native chemicals	27
Valorization of dragon fruit waste to value-added bioproducts and formulations: A review	26
Chromatin modifications and memory in regulation of stress-related polyphenols: finding new ways to control flavonoid biosynthesis	26
Bioactive peptides with potential anticancer properties from various food protein sources: status of recent research, production technologies, and developments	25
Xylooligosaccharides mediated gut microbiome modulation: prebiotics to postbiotics	25
Fashion meets science: how advanced breeding approaches could revolutionize the textile industry	25
Hosts engineering and in vitro enzymatic synthesis for the discovery of novel natural products and their derivatives	24
Fermentation strategies to improve propionic acid production withpropionibacteriumssp.: a review	23
Emerging trends in high-solids enzymatic saccharification of lignocellulosic feedstocks for developing an efficient and industrially deployable sugar platform	23
Advancements in multi-omics for nutraceutical enhancement and traits improvement in buckwheat	23
Recent advances in genome mining and synthetic biology for discovery and biosynthesis of natural products	23
Optimum chalcone synthase for flavonoid biosynthesis in microorganisms	23
Potential use of gene drive modified insects against disease vectors, agricultural pests and invasive species poses new challenges for risk assessment	23
A strategy of co-fermentation of distillers dried grains with solubles (DDGS) and lignocellulosic feedstocks as swine feed	23
Biocontrol of plant pathogens in omics era—with special focus on endophytic bacilli	22
Gauging the trends of pseudogenes in plants	22
Rhodococcus: sequences of genetic parts, analysis of their functionality, and development prospects as a molecular biology platform	22
Structural diversity, biosynthesis, and health-promoting properties of brown algal meroditerpenoids	22
Thraustochytrids as a promising source of fatty acids, carotenoids, and sterols: bioactive compound biosynthesis, and modern biotechnology	22
A review on biomass-derived levulinic acid for application in drug synthesis	22
Bioproduction of porphyrins, phycobilins, and their proteins using microbial cell factories: engineering, metabolic regulations, challenges, and perspectives	21

The secretory pathway – the key for unlocking the potential of Chinese hamster ovary cell factories for manufacturing therapeutic proteins	21
Modular tuning engineering and versatile applications of genetically encoded biosensors	19
Antiviral and antibacterial properties of phloroglucinols: a review on naturally occurring and (semi)synthetic derivatives with potential therapeutic interest	19
Molecular approaches to enhance astaxanthin biosynthesis; future outlook: engineering of transcription factors in Haematococcus pluvialis	19
Metabolic engineering strategies to enable microbial electrosynthesis utilization of CO ₂ : recent progress and challenges	19