OOIR: Observatory of International Research

Papers

(The TQCC of Genetic Epidemiology is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
Are trait‐associated genes clustered together in a gene network?	294
A gene‐based association test of interactions for maternal–fetal genotypes identifies genes associated with nonsyndromic congenital heart defects	117
Deconvolution analysis of cell‐type expression from bulk tissues by integrating with single‐cell expression reference	49
A Brief History behind the journal Genetic Epidemiology and the International Genetic Epidemiology Society	45
Statistics to prioritize rare variants in family‐based sequencing studies with disease subtypes	41
Gene‐level association analysis of ordinal traits with functional ordinal logistic regressions	24
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A Novel One‐Sample Mendelian Randomization Approach for Count‐Type Outcomes That Is Robust to Correlated and Uncorrelated Pleiotropic Effects	22
Bias and mean squared error in Mendelian randomization with invalid instrumental variables	16
A two‐sample robust Bayesian Mendelian Randomization method accounting for linkage disequilibrium and idiosyncratic pleiotropy with applications to the COVID‐19 outcomes	15
Statistical power of transcriptome‐wide association studies	15
Adjusting for collider bias in genetic association studies using instrumental variable methods	14
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Issue Information	12
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Issue Information	12
Causation and familial confounding as explanations for the associations of polygenic risk scores with breast cancer: Evidence from innovative ICE FALCON and ICE CRISTAL analyses	11
Multivariable MR Can Mitigate Bias in Two‐Sample MR Using Covariable‐Adjusted Summary Associations	10
A Robust Association Test Leveraging Unknown Genetic Interactions: Application to Cystic Fibrosis Lung Disease	10
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Issue Information	9
Genome‐wide association studies of 27 accelerometry‐derived physical activity measurements identified novel loci and genetic mechanisms	9
Gene‐level association analysis of bivariate ordinal traits with functional regressions	9
Collider bias from selecting disease samples distorts causal inferences	8

Effect of case and control definitions on genome‐wide association study (GWAS) findings	8
Sensitivity analyses gain relevance by fixing parameters observable during the empirical analyses	7
Uncovering Ethnicity‐Specific Recessive Loci for Alzheimer's Disease in 89 Dominican Families Using Family‐Based WGS Analysis	7
Multivariate analysis of a missense variant in CREBRF reveals associations with measures of adiposity in people of Polynesian ancestries	6
Gene‐environment interaction in type 2 diabetes in Korean cohorts: Interaction of a type 2 diabetes polygenic risk score with triglyceride and cholesterol on fasting glucose levels	5
A Mixed‐Effect Kernel Machine Regression Model for Integrative Analysis of Alpha Diversity in Microbiome Studies	5
Structured testing of genetic association with mixed clinical outcomes	5
Control for population stratification in genetic association studies based on GWAS summary statistics	5
Integrating external controls in case–control studies improves power for rare‐variant tests	5
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Genome‐wide association study of multiethnic nonsyndromic orofacial cleft families identifies novel loci specific to family and phenotypic subtypes	5
Investigating the prediction of CpG methylation levels from SNP genotype data to help elucidate relationships between methylation, gene expression and complex traits	5
Novel HLA associations with outcomes of Mycobacterium tuberculosis exposure and sarcoidosis in individuals of African ancestry using nearest‐neighbor feature selection	4
Methods for large‐scale single mediator hypothesis testing: Possible choices and comparisons	4
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Ethical, Legal, and Social Implications of Gene‐Environment Interaction Research	4
Issue Information	4
Issue Information	4
The influence of unmeasured confounding on the MR Steiger approach	3
Genome‐Wide Association Analyses in Family Triads and Dyads Following Assisted Reproductive Technology	3
Dimension Reduction Using Local Principal Components for Regression‐Based Multi‐SNP Analysis in 1000 Genomes and the Canadian Longitudinal Study on Aging (CLSA)	3
Bayesian Effect Size Ranking to Prioritise Genetic Risk Variants in Common Diseases for Follow‐Up Studies	3
Exploring polygenic‐environment and residual‐environment interactions for depressive symptoms within the UK Biobank	3
simmrd: An open‐source tool to perform simulations in Mendelian randomization	3
Abstracts	3
Meta‐analysis of breast cancer risk for individuals with PALB2 pathogenic variants	3
Phenotypic variance partitioning by transcriptomic gene expression levels and environmental variables for anthropometric traits using GTEx data	3
Parent‐of‐Origin Effects in Childhood Asthma at Seven Years of Age	3