OOIR: Observatory of International Research

Papers

(The TQCC of Genetic Epidemiology is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
A gene‐based association test of interactions for maternal–fetal genotypes identifies genes associated with nonsyndromic congenital heart defects	349
A Brief History behind the journal Genetic Epidemiology and the International Genetic Epidemiology Society	133
Statistics to prioritize rare variants in family‐based sequencing studies with disease subtypes	69
Deconvolution analysis of cell‐type expression from bulk tissues by integrating with single‐cell expression reference	48
Are trait‐associated genes clustered together in a gene network?	45
Statistical power of transcriptome‐wide association studies	24
A Novel One‐Sample Mendelian Randomization Approach for Count‐Type Outcomes That Is Robust to Correlated and Uncorrelated Pleiotropic Effects	20
Bias and mean squared error in Mendelian randomization with invalid instrumental variables	16
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MELODY: Mediation Analysis in Logistic Regression for High‐Dimensional Mediators and a Binary Outcome	15
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Issue Information	13
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Integrative Harmonization of Phenotypic and Genomic Data Improves Bone Mineral Density Prediction in Multi‐Study Osteoporosis Research	11
Multivariable MR Can Mitigate Bias in Two‐Sample MR Using Covariable‐Adjusted Summary Associations	10
Gene‐level association analysis of bivariate ordinal traits with functional regressions	10
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Causation and familial confounding as explanations for the associations of polygenic risk scores with breast cancer: Evidence from innovative ICE FALCON and ICE CRISTAL analyses	9
Issue Information	7
Uncovering Ethnicity‐Specific Recessive Loci for Alzheimer's Disease in 89 Dominican Families Using Family‐Based WGS Analysis	7
A Robust Association Test Leveraging Unknown Genetic Interactions: Application to Cystic Fibrosis Lung Disease	7
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Sensitivity analyses gain relevance by fixing parameters observable during the empirical analyses	6
Multivariate analysis of a missense variant in CREBRF reveals associations with measures of adiposity in people of Polynesian ancestries	6
Effect of case and control definitions on genome‐wide association study (GWAS) findings	6
Control for population stratification in genetic association studies based on GWAS summary statistics	5
Investigating the prediction of CpG methylation levels from SNP genotype data to help elucidate relationships between methylation, gene expression and complex traits	5
Structured testing of genetic association with mixed clinical outcomes	5
A Mixed‐Effect Kernel Machine Regression Model for Integrative Analysis of Alpha Diversity in Microbiome Studies	5
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Issue Information	4
Novel HLA associations with outcomes of Mycobacterium tuberculosis exposure and sarcoidosis in individuals of African ancestry using nearest‐neighbor feature selection	4
Correction to “Multivariable MR Can Mitigate Bias in Two‐Sample MR Using Covariable‐Adjusted Summary Associations”	4
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Ethical, Legal, and Social Implications of Gene‐Environment Interaction Research	4
Methods for large‐scale single mediator hypothesis testing: Possible choices and comparisons	4
Abstracts	4
Dimension Reduction Using Local Principal Components for Regression‐Based Multi‐SNP Analysis in 1000 Genomes and the Canadian Longitudinal Study on Aging (CLSA)	3
Phenotypic variance partitioning by transcriptomic gene expression levels and environmental variables for anthropometric traits using GTEx data	3
Statistical learning for sparser fine‐mapped polygenic models: The prediction of LDL‐cholesterol	3
Bayesian Effect Size Ranking to Prioritise Genetic Risk Variants in Common Diseases for Follow‐Up Studies	3
Meta‐analysis of breast cancer risk for individuals with PALB2 pathogenic variants	3
Parent‐of‐Origin Effects in Childhood Asthma at Seven Years of Age	3
Genome‐Wide Association Analyses in Family Triads and Dyads Following Assisted Reproductive Technology	3
simmrd: An open‐source tool to perform simulations in Mendelian randomization	3
Evaluating a Mendelian Risk Prediction Model That Aggregates Across Genes and Cancers	2
Data‐adaptive and pathway‐based tests for association studies between somatic mutations and germline variations in human cancers	2
Sparse group variable selection for gene–environment interactions in the longitudinal study	2
Use of genetic correlations to examine selection bias	2
Abstracts	2
Improved two‐step testing of genome‐wide gene–environment interactions	2
Shared and Distinct Genetic Factors Underlying Bile Acid Regulation and Intrahepatic Cholestasis of Pregnancy	2
Issue Information	2
Limitation of permutation‐based differential correlation analysis	2
Genetic heterogeneity: Challenges, impacts, and methods through an associative lens	2
Using parent‐offspring pairs and trios to estimate indirect genetic effects in education	2
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Genetic Associations of Persistent Opioid Use After Surgery Point to OPRM1 but Not Other Opioid‐Related Loci as the Main Driver of Opioid Use Disorder	2
Comparison of regmed and BayesNetty for exploring causal models with many variables	2
Sex‐Specific Association Between Polymorphisms in Estrogen Receptor Alpha Gene (ESR1) and Depression: A Genome‐Wide Association Study of All of Us and UK Biobank Data	2
Issue Information	2
Bias correction for inverse variance weighting Mendelian randomization	2
Correction to “Abstracts”	2
General Kernel Machine Methods for Multi‐Omics Integration and Genome‐Wide Association Testing With Related Individuals	2
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Using Family History Data to Improve the Power of Association Studies: Application to Cancer in UK Biobank	2
Issue Information	2