Journal of Pineal Research

Article	Citations
Transcriptomic and Metabolomic Signatures of Acute Circadian Misalignment in Mice	135
RETRACTION: Changes in the Expression of Melatonin Receptors Induced by Melatonin Treatment in Hepatocarcinoma HepG2 Cells	70
Correction to high sensitivity of melatonin suppression response to evening light in preschool‐aged children	69
Microbial Melatonin Production Improves Plant Metabolic Function in Short‐Term Climate‐Induced Stresses	60
Therapeutic Potential of Melatonin in Gastrointestinal Cancers: Molecular Mechanisms, Preclinical Evidence and Clinical Implications	54
Melatonin targets MoIcl1 and works synergistically with fungicide isoprothiolane in rice blast control	54
Zygotic Exposure to Venlafaxine Disrupts the Circadian Locomotor Activity Behaviour in Zebrafish Larvae	52
Melatonin Increased Autophagy Level to Facilitate Osteogenesis of Inflamed PDLSCs Through TMEM110 Signaling Pathways	50
A phase II, single‐center, double‐blind, randomized placebo‐controlled trial to explore the efficacy and safety of intravenous melatonin in surgical patients with severe sepsis admitted to the intensi	50
Melatonin inhibits chondrosarcoma cell proliferation and metastasis by enhancing miR‐520f‐3p production and suppressing MMP7 expression	48
Melatonin mediates reactive oxygen species homeostasis via SlCV to regulate leaf senescence in tomato plants	47
Melatonin as a chronobiotic/cytoprotective agent in bone. Doses involved	46
BPS‐induced ovarian dysfunction: Protective actions of melatonin via modulation of SIRT‐1/Nrf2/NFĸB and IR/PI3K/pAkt/GLUT‐4 expressions in adult golden hamster	44
Erratum to: Mitochondrial cytochrome P450 (CYP) 1B1 is responsible for melatonin‐induced apoptosis in neural cancer cells	43
From Seasonality to Species Conservation: Chronobiological Research on European Hamsters in Strasbourg, France	39
Melatonin Ameliorates Atherosclerotic Plaque Vulnerability by Regulating PPARδ‐Associated Smooth Muscle Cell Phenotypic Switching	39
Anti‐PANoptosis is involved in neuroprotective effects of melatonin in acute ocular hypertension model	38
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Investigating the safety profiles of exogenous melatonin and associated adverse events: A pharmacovigilance study using WHO‐VigiBase	34
Light‐Dependent Circadian Rhythm Governs O‐GlcNAc Cycling to Influence Cognitive Function in Adult Zebrafish	34
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Melatonin Enhances Peanut Productivity by Enriching Root‐Associated Nitrogen‐Fixing Bacteria	34
Optimizing the Time and Dose of Melatonin as a Sleep‐Promoting Drug: A Systematic Review of Randomized Controlled Trials and Dose−Response Meta‐Analysis	33
Exogenous Melatonin Regulates Hormone Signalling and Photosynthesis‐Related Genes to Enhance Brassica napus. Yield: A Transcriptomic Perspective	33

RETRACTION: Melatonin Inhibits the Expression of the Inducible Isoform of Nitric Oxide Synthase and Nuclear Factor Kappa B Activation in Rat Skeletal Muscle	33
No association between a common type 2 diabetes risk gene variant in the melatonin receptor gene (MTNR1B) and mortality among type 2 diabetes patients	32
Correction to “Melatonin mediates selenium‐induced tolerance to cadmium stress in tomato plants”	32
From gestational chronodisruption to noncommunicable diseases: Pathophysiological mechanisms of programming of adult diseases, and the potential therapeutic role of melatonin	31
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Relationship Between Urinary 6‐Sulfatoxymelatonin Rhythms and the Bone Resorption Marker Amino‐Terminal Cross‐Linked Telopeptide of Collagen I in Blind Women	29
Melatonin improves skin barrier damage caused by sleep restriction through gut microbiota	29
Effect of melatonin cream on acute radiation dermatitis in patients with primary breast cancer: A double‐blind, randomized, placebo‐controlled trial	28
3‐Month Melatonin Supplementation to Reduce Brain Oxidative Stress and Improve Sleep in Mild Cognitive Impairment: A Randomised Controlled Feasibility Trial	28
Melatonin prevents EAAC1 deletion‐induced retinal ganglion cell degeneration by inhibiting apoptosis and senescence	28
Melatonin treatment improves ventricular conduction via upregulation of Nav1.5 channel proteins and sodium current in the normal rat heart	28
Predicting melatonin suppression by light in humans: Unifying photoreceptor‐based equivalent daylight illuminances, spectral composition, timing and duration of light exposure	27
Light Environment of Arctic Solstices is Coupled With Melatonin Phase‐Amplitude Changes and Decline of Metabolic Health	26
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In Vitro and In Vivo Effects of Melatonin‐Containing Combinations in Human Pancreatic Ductal Adenocarcinoma	24
Melatonin Rescues Influenza A Virus–Induced Cellular Energy Exhaustion via OMA1‐OPA1‐S in Acute Exacerbation of COPD	23
Melatonin Ameliorates Circadian Disruption‐Associated Dry Eye via Modulation of BMAL1‐REV‐ERBα‐IL‐17 Axis and Ocular Surface Microbiota Homeostasis	22
Single‐cell transcriptomic analysis reveals circadian rhythm disruption associated with poor prognosis and drug‐resistance in lung adenocarcinoma	22
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EXPRESSION OF CONCERN: Mitochondrial Function Is Controlled by Melatonin and Its Metabolites In Vitro in Human Melanoma Cells	22
Effect of melatonin on ATG2B‐mediated autophagy regulation in sheep granulosa cells with different FecB genotypes	21
Homeobox gene‐encoded transcription factors in development and mature circadian function of the rodent pineal gland	21
Orphan GPR50 Restrains Neurite Outgrowth and Cell Migration by Activating the G12/13 Protein‐RhoA Pathway in Neural Progenitor Cells and Tanycytes	21
Multi‐Omics Analysis Reveals That AhNHL Contributes to Melatonin‐Mediated Cadmium Tolerance in Peanut Plants	21
Melatonin Membrane Receptors in the Vascular System: Function, Modulation and Clinical Relevance	20
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NPAS2 Deficiency Leads to Antidepressant‐Like Behaviors in Mice by Modulating Astrocyte‐Mediated Neuroinflammation	19
Melatonin as a key regulator in seed germination under abiotic stress	18
Melatonin Alleviates Osteoarthritis by Regulating NADPH Oxidase 4–Induced Ferroptosis and Mitigating Mitochondrial Dysfunction	18
Melatonin Affects Peucedanum praeruptorum Vegetative Growth and Coumarin Synthesis by Modulating the Antioxidant System, Photosynthesis, and Endogenous Hormones	18
Melatonin, an Antitumor Necrosis Factor Therapy	17
Protective Effects of Melatonin on Kidney Function Against Contrast Media‐Induced Kidney Damage in Patients With Chronic Kidney Disease: A Prospective, Randomized, Double‐Blinded, Placebo‐Controlled T	17
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Mouse Models in Circadian Rhythm and Melatonin Research	17
Relating Photoperiod and Outdoor Temperature With Sleep Architecture in Patients With Neuropsychiatric Sleep Disorders	17
Thirty‐seven years of MT1 and MT2 melatonin receptor localization in the brain: Past and future challenges	16
The Mechanism by Which Melatonin Improves the Dysregulation of Glucose and Lipid Metabolism in Castrated Female Mice	16
IAT4 , a New Indolamine N ‐Acetyltransferase in Saccharomyces cerevisiae Involv	16
Correction to “Melatonin/PGC1A/UCP1 promotes tumor slimming and represses tumor progression by initiating autophagy and lipid browning”	16
Melatonin inhibits endometriosis development by disrupting mitochondrial function and regulating tiRNAs	16
Melatonin MT1 receptors regulate the Sirt1/Nrf2/Ho‐1/Gpx4 pathway to prevent α‐synuclein‐induced ferroptosis in Parkinson's disease	15
High sensitivity of melatonin suppression response to evening light in preschool‐aged children	15
Melatonin protects against developmental PBDE‐47 neurotoxicity by targeting the AMPK/mitophagy axis	15
Melatonin Inhibits Endometriosis Growth via Specific Binding and Inhibition of EGFR Phosphorylation	15
Cyclic uniaxial mechanical load enhances chondrogenesis through entraining the molecular circadian clock	15
Melatonin and Exercise Restore Myogenesis and Mitochondrial Dynamics Deficits Associated With Sarcopenia in iMS‐ Bmal1 −/−	15
Melatonin sensitizes leukemia cells to the MCL1 inhibitors S63845 and A‐1210477 through multiple pathways	14
RETRACTION: Melatonin Inhibits Autophagy and Endoplasmic Reticulum Stress in Mice With Carbon Tetrachloride‐Induced Fibrosis	14
Greater sensitivity of the circadian system of women to bright light, but not dim‐to‐moderate light	14

Hypnotic effects of melatonin depend on the environmental lighting conditions in the rat	14
Melatonin Supplementation Alleviates Bone Mineral Density Decline and Circulating Oxidative Stress in Iron‐Overloaded Thalassemia Patients	13
Melatonin Regulates Neuronal Synaptic Plasticity in the Supramammillary Nucleus and Attenuates Methamphetamine‐Induced Conditioned Place Preference and Sensitization in Mice	13
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Zebrafish Dark‐Dependent Behavior Requires Phototransduction by the Pineal Gland	13
Melatonin Regulates Rheumatoid Synovial Fibroblasts‐Related Inflammation: Implications for Pathological Skeletal Muscle Treatment	13
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Direct Peritoneal Resuscitation and Melatonin in the Treatment of Abdominal Sepsis‐Induced Lung Injury via Macrophage Metabolic Reprogramming	12
Standardized and Calibrated Light Stimuli via Head‐Mounted Displays for Investigating the Nonvisual Effects of Light	12
Criticism on the Incorrect Use of Oxygen–Ozone Therapy in Medicine	12
Quality‐of‐life outcomes following topical melatonin application against acute radiation dermatitis in patients with early breast cancer: A double‐blind, randomized, placebo‐controlled trial	12
Histone deacetylase 9 regulates disease resistance through fine‐tuning histone deacetylation of melatonin biosynthetic genes and melatonin accumulation in cassava	12
KARS Mutations Impair Brain Myelination by Inducing Oligodendrocyte Deficiency: One Potential Mechanism and Improvement by Melatonin	12
Cross‐species single‐cell landscape of vertebrate pineal gland	12
Melatonin functions as a broad‐spectrum antifungal by targeting a conserved pathogen protein kinase	11
Correction to “Effects of melatonin on fatty liver disease: The role of NR4A1/DNA‐PKcs/p53 pathway, mitochondrial fission, and mitophagy”	11
OPA1 Mediated Fatty Acid β‐Oxidation in Hepatocyte: The Novel Insight for Melatonin Attenuated Apoptosis in Concanavalin A Induced Acute Liver Injury	11
Coupling Melatonin and Ultrasound Modulates ROS Production, Antioxidant System, and Biochemical Attributes Linked to Oxidative Browning in Litchi Pericarp	11
Melatonin receptor structure and signaling	11
Melatonin reduces brain injury following inflammation‐amplified hypoxia–ischemia in a translational newborn piglet study of neonatal encephalopathy	11
Melatonin, Melatonin Receptors and Sleep: Moving Beyond Traditional Views	11
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Melatonin and Seasonal Synchrony in Mammals	11
Melatonin rescues the mitochondrial function of bone marrow‐derived mesenchymal stem cells and improves the repair of osteoporotic bone defect in ovariectomized rats	11
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Key Role of the CRE Sequence in the Per1 Promoter in Mediating the Switch Between Unipolar and Bipolar Depression‐Like Behaviors	11
Dose assessment of melatonin in sepsis (DAMSEL2) study: Pharmacokinetics of two doses of oral melatonin in patients with sepsis	10
Melatonin alleviates myocardial dysfunction through inhibition of endothelial‐to‐mesenchymal transition via the NF‐κB pathway	10
Melatonin‐mediated malic enzyme 2 orchestrates mitochondrial fusion and respiratory functions to promote odontoblastic differentiation during tooth development	10
Evening chronotype is associated with hormonal and metabolic disorders in polycystic ovary syndrome	9
Melatonin Alleviates Oxidative Stress‐Induced Mitochondrial Dysfunction Through Ameliorating NAD + Homeostasis of hDPSCs for Cell‐Based Therapy	9
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Melatonin Overcomes Cancer Multidrug Resistance by Downregulating ABCB1 Expression and Modulating Mitochondrial Function	9
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RETRACTION: Melatonin Modulates Dysregulated Circadian Clocks in Mice With Diethylnitrosamine‐Induced Hepatocellular Carcinoma	9
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Biosynthesis of neuroprotective melatonin is dysregulated in Huntington's disease	9
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Melatonin facts: Lack of evidence that melatonin is a radical scavenger in living systems	9
RETRACTION: Melatonin Induces Cell Cycle Arrest and Apoptosis in Hepatocarcinoma HepG2 Cell Line	8
Protective Activity of Melatonin Combinations and Melatonin‐Based Hybrid Molecules in Neurodegenerative Diseases	8
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Melatonin may suppress lung adenocarcinoma progression via regulation of the circular noncoding RNA hsa_circ_0017109/miR‐135b‐3p/TOX3 axis	8
Design, Synthesis, and Antifungal Activity of Melatonin Derivatives Containing a (Thio)Semicarbazide Group	8
Identification of a COMT Gene Involved in the Biosynthesis of Melatonin Which Mediates Resistance to Citrus Canker	8
Identification of Predictors of Shift Work Adaptation and Its Association With Immune, Hormonal and Metabolite Biomarkers	8
Light and Temperature Coordinately Regulate Phytomelatonin Synthesis to Maintain Plant Morphogenesis via the COP1‐HY5 Module	7
Primary Gamma Knife Radiosurgery for pineal region tumors: A systematic review and pooled analysis of available literature with histological stratification	7
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Correction to “PP2C1 Fine‐Tunes Melatonin Biosynthesis and Phytomelatonin Receptor PMTR1 Binding to Melatonin in Cassava”	7
Proteomic Signatures Underlying Sleep, Circadian Activity Patterns, and Major Chronic Diseases	7
Delayed circadian rhythms in older Africans living with human immunodeficiency virus (HIV)	7
Meditation Linked to Enhanced MRI Signal Intensity in the Pineal Gland and Reduced Predicted Brain Age	7
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Melatonin: A Potential Therapy for Osteoporosis With Insights Into Molecular Mechanisms	7
Melatonin improves cardiac remodeling and brain–heart sympathetic hyperactivation aggravated by light disruption after myocardial infarction	7
Corrigendum to “melatonin ameliorates PM2.5‐induced cardiac perivascular fibrosis through regulating mitochondrial redox homeostasis”	7
RETRACTION: Melatonin Inhibits the Sphingosine Kinase 1/Sphingosine‐1‐Phosphate Signaling Pathway in Rabbits With Fulminant Hepatitis of Viral Origin	7
Melatonin Protects Against Colistin‐Induced Intestinal Inflammation and Microbiota Dysbiosis	6
Functional Characterization of GNA1 as a Serotonin N ‐Acetyltransferase Reveals a Key Role in the Serotonin to Melatonin Pathway in <	6
RP58 knockdown contributes to hypoxia‐ischemia‐induced pineal dysfunction and circadian rhythm disruption in neonatal rats	6
Mechanism of Exogenous Melatonin to Alleviate the Fermentation Performance of Saccharomyces cerevisiae Under Copper Stress	6
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Melatonin drives apoptosis in head and neck cancer by increasing mitochondrial ROS generated via reverse electron transport	6
Ramelteon for delirium prevention in hospitalized patients: An updated meta‐analysis and trial sequential analysis of randomized controlled trials	6
Melatonin ameliorates myocardial infarction in obese diabetic individuals: The possible involvement of macrophage apoptotic factors	6
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Chronic developmental hypoxia alters mitochondrial oxidative capacity and reactive oxygen species production in the fetal rat heart in a sex‐dependent manner	6
Novel melatonin‐producing Bacillus safensis EH143 mitigates salt and cadmium stress in soybean	6
In vitro deacetylation of N‐acetylserotonin by arylacetamide deacetylase	5
Exogenous Melatonin Enhances Waterlogging Tolerance in Sesame by Modulating Physiological, Biochemical, and Proteomic Responses	5
Recharge of chondrocyte mitochondria by sustained release of melatonin protects cartilage matrix homeostasis in osteoarthritis	5
Melatonin alleviates PM2.5‐induced glucose metabolism disorder and lipidome alteration by regulating endoplasmic reticulum stress	5
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RETRACTION: Melatonin Prevents Deregulation of the Sphingosine Kinase/Sphingosine 1‐Phosphate Signaling Pathway in a Mouse Model of Diethylnitrosamine‐Induced Hepatocellular Carcinoma	5

Relationship Between Melatonin Receptor Agonists and Parkinson's Disease	5
The ISL LIM‐homeobox 2 transcription factor is negatively regulated by circadian adrenergic signaling to repress the expression of Aanat in pinealocytes of the rat pineal gland	5
Resetting of the Human Circadian Melatonin Rhythm by Ambient Hypoxia	5
Melatonin Repairs the Lipidome of Human Hepatocytes Exposed to Cd and Free Fatty Acid‐Induced Lipotoxicity	5
Melatonin Prevents Thioacetamide–Induced Gut Leakiness and Liver Fibrosis Through the Gut–Liver Axis via Modulating Sirt1‐Related Deacetylation of Gut Junctional Complex and Hepatic Proteins	5
Rational modification of melatonin for broad‐spectrum antifungal agents discovery	4
RETRACTION: Melatonin Attenuates Apoptotic Liver Damage in Fulminant Hepatic Failure Induced by the Rabbit Hemorrhagic Disease Virus	4
Adrenergic Agonists Activate Transcriptional Activity in Immortalized Neuronal Cells From the Mouse Suprachiasmatic Nucleus	4
Melatonin suppresses the metastatic potential of osteoblastic prostate cancers by inhibiting integrin α2β1 expression	4
Melatonin Enhances Aquaporin 4 and Alpha‐Syntrophin Interaction by Inhibiting Cyclin‐Dependent Kinase 5 Activity to Preserve Glymphatic Function in Neonatal Hypoxic‐Ischemic Encephalopathy	4
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Correction to “Melatonin Inhibits Cd4+ T Cell Apoptosis via the Bcl‐2/BAX Pathway and Improves Survival Rates in Mice With Sepsis”	4
N1‐Acetyl‐5‐methoxykynuramine, which decreases in the hippocampus with aging, improves long‐term memory via CaMKII/CREB phosphorylation	4
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Circadian Rhythm Timing and Associations With Sleep Symptoms in People With Insomnia	4
Safety and efficacy of melatonin supplementation as an add‐on treatment for infantile epileptic spasms syndrome: A randomized, placebo‐controlled, double‐blind trial	4
iMS‐Bmal1−/− mice show evident signs of sarcopenia that are counteracted by exercise and melatonin therapies	3
Modeling Genetic Risk of β‐Cell Dysfunction in Human Induced Pluripotent Stem Cells From Patients Carrying the MTNR1B Risk Variant	3
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RETRACTION: Regulation of Prostaglandin Production in Carrageenan‐Induced Pleurisy Melatonin	3
Shift and longtime light induces endometrioid adenocarcinoma via activation of PKC‐α/Akt pathway in female golden hamster: Involvement of altered Aanat and Bmal1 rhythm	3
Ramelteon attenuates hippocampal neuronal loss and memory impairment following kainate‐induced seizures	3
Melatonin Boosts the Phytochemical Profile of Blood Oranges, Enhancing (Poly)phenol and Endogenous Melatonin Content, Through Pre‐ and Postharvest Treatments	3
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Healthy Lifestyles Modify the Association of Melatonin Receptor 1B Gene and Ischemic Stroke: A Family‐Based Cohort Study in Northern China	3
Melatonin suppression by light involves different retinal photoreceptors in young and older adults	3
Discovery Begets Discovery: Special Edition on Melatonin and the Musculoskeletal System	3
Melatonin Induces PERK‐ATF4 Unfolded Protein Response and Apoptosis in Human Choriocarcinoma Cells	3
Melatonin and aggressive behavior: A systematic review of the literature on preclinical and clinical evidence	3
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Journal of Pineal Research guidelines for authors: Melatonin studies using plants	3
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Industrial and academic approaches to the search for alternative melatonin receptor ligands: An historical survey	3