Journal of Pineal Research

Article	Citations
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RETRACTION: Effects of Melatonin on Fatty Liver Disease: The Role of NR4A1/DNA‐Pkcs/P53 Pathway, Mitochondrial Fission, and Mitophagy	100
Weekly and seasonal variation in the circadian melatonin rhythm in humans: A response	89
Melatonin increases susceptibility to atrial fibrillation in obesity via Akt signaling impairment in response to lipid overload	82
Paternal sleep deprivation induces metabolic perturbations in male offspring via altered LRP5 DNA methylation of pancreatic islets	73
Retraction Statement: Melatonin plus porcine bone on discrete calcium deposit implant surface stimulates osteointegration in dental implants	61
RETRACTION: Melatonin Prevents Oxidative Stress and Changes in Antioxidant Enzyme Expression and Activity in the Liver of Aging Rats	57
RETRACTION: Changes in the Expression of Melatonin Receptors Induced by Melatonin Treatment in Hepatocarcinoma HepG2 Cells	54
RETRACTION: Melatonin Inhibits Autophagy and Endoplasmic Reticulum Stress in Mice With Carbon Tetrachloride‐Induced Fibrosis	53
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Melatonin targets MoIcl1 and works synergistically with fungicide isoprothiolane in rice blast control	40
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YTHDF3 Regulates the Degradation and Stability of m6A‐Enriched Transcripts to Facilitate the Progression of Castration‐Resistant Prostate Cancer	36
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The effect of melatonin on glucose tolerance, insulin sensitivity and lipid profiles after a late evening meal in healthy young males	34
Fate of melatonin orally administered in preterm newborns: Antioxidant performance and basis for neuroprotection	34
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Differentiation of T cells producing interleukin‐17 (Th17) against the background of exogenous melatonin during pregnancy	32
Hypnotic effects of melatonin depend on the environmental lighting conditions in the rat	32
Melatonin promotes the proliferation of primordial germ cell‐like cells derived from porcine skin‐derived stem cells: A mechanistic analysis	32

The mammalian gastro‐intestinal tract is a NOT a major extra‐pineal source of melatonin	31
Melatonin alters the excitability of mouse cerebellar granule neurons by inhibiting voltage‐gated sodium, potassium, and calcium channels	30
A phase II, single‐center, double‐blind, randomized placebo‐controlled trial to explore the efficacy and safety of intravenous melatonin in surgical patients with severe sepsis admitted to the intensi	30
Melatonin inhibits chondrosarcoma cell proliferation and metastasis by enhancing miR‐520f‐3p production and suppressing MMP7 expression	29
Timing Matters: Late, but Not Early, Exercise Training Ameliorates MASLD in Part by Modulating the Gut‐Liver Axis in Mice	28
Role of melanocortin system in the locomotor activity rhythms and melatonin secretion as revealed by agouti‐signalling protein (asip1) overexpression in zebrafish	28
Melatonin Regulates Rheumatoid Synovial Fibroblasts‐Related Inflammation: Implications for Pathological Skeletal Muscle Treatment	27
Melatonin Regulates Neuronal Synaptic Plasticity in the Supramammillary Nucleus and Attenuates Methamphetamine‐Induced Conditioned Place Preference and Sensitization in Mice	27
Zygotic Exposure to Venlafaxine Disrupts the Circadian Locomotor Activity Behaviour in Zebrafish Larvae	27
Zebrafish Dark‐Dependent Behavior Requires Phototransduction by the Pineal Gland	26
Melatonin multifaceted pharmacological actions on melatonin receptors converging to abrogate COVID‐19	26
In vitro deacetylation of N‐acetylserotonin by arylacetamide deacetylase	25
Maternal melatonin: Effective intervention against developmental programming of cardiovascular dysfunction in adult offspring of complicated pregnancy	25
Extracellular vesicles derived from melatonin‐preconditioned mesenchymal stem cells containing USP29 repair traumatic spinal cord injury by stabilizing NRF2	25
Impact of endogenous melatonin on rhythmic behaviors, reproduction, and survival revealed in melatonin‐proficient C57BL/6J congenic mice	25
Correction to high sensitivity of melatonin suppression response to evening light in preschool‐aged children	25
Melatonin and the health of menopausal women: A systematic review	24
N‐Acetylserotonin is an oxidation‐responsive activator of Nrf2 ameliorating colitis in rats	24
Safety of higher doses of melatonin in adults: A systematic review and meta‐analysis	23
Circadian desynchrony and glucose metabolism	23
Daytime light exposure is a strong predictor of seasonal variation in sleep and circadian timing of university students	23
Melatonin drives apoptosis in head and neck cancer by increasing mitochondrial ROS generated via reverse electron transport	22
Melatonin Increased Autophagy Level to Facilitate Osteogenesis of Inflamed PDLSCs Through TMEM110 Signaling Pathways	22
High dose melatonin increases sleep duration during nighttime and daytime sleep episodes in older adults	22
Melatonin mediates reactive oxygen species homeostasis via SlCV to regulate leaf senescence in tomato plants	21
Melatonin restores endoplasmic reticulum homeostasis to protect injured neurons in a rat model of chronic cervical cord compression	20
Greater sensitivity of the circadian system of women to bright light, but not dim‐to‐moderate light	19
Melatonin restores hepatic lipid metabolic homeostasis disrupted by blue light at night in high‐fat diet‐fed mice	19
BPS‐induced ovarian dysfunction: Protective actions of melatonin via modulation of SIRT‐1/Nrf2/NFĸB and IR/PI3K/pAkt/GLUT‐4 expressions in adult golden hamster	19
Melatonin pretreatment alleviates the long‐term synaptic toxicity and dysmyelination induced by neonatal Sevoflurane exposure via MT1 receptor‐mediated Wnt signaling modulation	18
Melatonin as a chronobiotic/cytoprotective agent in bone. Doses involved	18
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Endogenous circadian regulation and phase resetting of clinical metabolic biomarkers	17
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KARS Mutations Impair Brain Myelination by Inducing Oligodendrocyte Deficiency: One Potential Mechanism and Improvement by Melatonin	15
Melatonin modulates metabolic remodeling in HNSCC by suppressing MTHFD1L‐formate axis	15
Melatonin and Seasonal Synchrony in Mammals	15
ABCG2 transporter plays a key role in the biodistribution of melatonin and its main metabolites	14
The role of circadian phase in sleep and performance during Antarctic winter expeditions	14
Melatonin Ameliorates Atherosclerotic Plaque Vulnerability by Regulating PPARδ‐Associated Smooth Muscle Cell Phenotypic Switching	14
The phytomelatonin receptor PMTR1 regulates seed development and germination by modulating abscisic acid homeostasis in Arabidopsis thaliana	14
Cross‐species single‐cell landscape of vertebrate pineal gland	13
Light‐Dependent Circadian Rhythm Governs O‐GlcNAc Cycling to Influence Cognitive Function in Adult Zebrafish	13
Glial cells expressing visual cycle genes are vital for photoreceptor survival in the zebrafish pineal gland	13
The ISL LIM‐homeobox 2 transcription factor is negatively regulated by circadian adrenergic signaling to repress the expression of Aanat in pinealocytes of the rat pineal gland	13

Melatonin alleviates the heat stress‐induced impairment of Sertoli cells by reprogramming glucose metabolism	13
Melatonin reduces brain injury following inflammation‐amplified hypoxia–ischemia in a translational newborn piglet study of neonatal encephalopathy	13
Melatonin Prevents Thioacetamide–Induced Gut Leakiness and Liver Fibrosis Through the Gut–Liver Axis via Modulating Sirt1‐Related Deacetylation of Gut Junctional Complex and Hepatic Proteins	12
Disruption of Melatonin Signaling Leads to Lipids Accumulation in the Liver of Melatonin Proficient Mice	12
Optimizing the Time and Dose of Melatonin as a Sleep‐Promoting Drug: A Systematic Review of Randomized Controlled Trials and Dose−Response Meta‐Analysis	12
Melatonin Priming Promotes Crop Seed Germination and Seedling Establishment Under Flooding Stress by Mediating ABA, GA, and ROS Cascades	12
The MT1 receptor as the target of ramelteon neuroprotection in ischemic stroke	12
Investigating the safety profiles of exogenous melatonin and associated adverse events: A pharmacovigilance study using WHO‐VigiBase	12
Relationship Between Melatonin Receptor Agonists and Parkinson's Disease	12
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Histone deacetylase 9 regulates disease resistance through fine‐tuning histone deacetylation of melatonin biosynthetic genes and melatonin accumulation in cassava	11
Heat Treatment of Saliva to Reduce Infectious Disease Contamination Does Not Impact the Analysis of Melatonin by Radioimmunoassay	11
Criticism on the Incorrect Use of Oxygen–Ozone Therapy in Medicine	11
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RETRACTION: Melatonin Prevents Deregulation of the Sphingosine Kinase/Sphingosine 1‐Phosphate Signaling Pathway in a Mouse Model of Diethylnitrosamine‐Induced Hepatocellular Carcinoma	10
Resetting of the Human Circadian Melatonin Rhythm by Ambient Hypoxia	10
Corrigendum	10
Erratum to: Mitochondrial cytochrome P450 (CYP) 1B1 is responsible for melatonin‐induced apoptosis in neural cancer cells	10
Retraction Statement: Actions of melatonin mixed with collagenized porcine bone versus porcine bone only on osteointegration of dental implants	10
Anti‐PANoptosis is involved in neuroprotective effects of melatonin in acute ocular hypertension model	9
RETRACTION: Protective Effect of Melatonin in a Non‐Septic Shock Model Induced by Zymosan in the Rat	9
Melatonin use and the risk of 30‐day mortality among US veterans with sepsis: A retrospective study	9
From Seasonality to Species Conservation: Chronobiological Research on European Hamsters in Strasbourg, France	9
Melatonin alleviates PM2.5‐induced glucose metabolism disorder and lipidome alteration by regulating endoplasmic reticulum stress	9
Melatonin receptor structure and signaling	8
Quality‐of‐life outcomes following topical melatonin application against acute radiation dermatitis in patients with early breast cancer: A double‐blind, randomized, placebo‐controlled trial	8
Melatonin functions as a broad‐spectrum antifungal by targeting a conserved pathogen protein kinase	8
Melatonin effects on bone: Implications for use as a therapy for managing bone loss	8
Diurnal Variation in Melatonin‐Mediated Cardiac Protection via Per2 Expression in Heart	8
Weekly and seasonal variation in the circadian melatonin rhythm in humans: Entrained to local clock time, social time, light exposure or sun time?	8
Melatonin ameliorates 10‐hydroxycamptothecin‐induced oxidative stress and apoptosis via autophagy‐regulated p62/Keap1/Nrf2 pathway in mouse testicular cells	8
Melatonin, Melatonin Receptors and Sleep: Moving Beyond Traditional Views	8
Melatonin Deficits Result in Pathologic Metabolic Reprogramming in Differentiated Neurons	8
Recharge of chondrocyte mitochondria by sustained release of melatonin protects cartilage matrix homeostasis in osteoarthritis	8
In‐person vs home schooling during the COVID‐19 pandemic: Differences in sleep, circadian timing, and mood in early adolescence	8
A hypothetical role for autophagy during the day/night rhythm‐regulated melatonin synthesis in the rat pineal gland	7
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No association between a common type 2 diabetes risk gene variant in the melatonin receptor gene (MTNR1B) and mortality among type 2 diabetes patients	7
Melatonin rescues the mitochondrial function of bone marrow‐derived mesenchymal stem cells and improves the repair of osteoporotic bone defect in ovariectomized rats	7
Disruption of serotonin biosynthesis increases resistance to striped stem borer without changing innate defense response in rice	7
Melatonin Alleviates Circadian Rhythm Disruption‐Induced Enhanced Luteinizing Hormone Pulse Frequency and Ovarian Dysfunction	7
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Rational modification of melatonin for broad‐spectrum antifungal agents discovery	7
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RETRACTION: Melatonin Attenuates Apoptotic Liver Damage in Fulminant Hepatic Failure Induced by the Rabbit Hemorrhagic Disease Virus	7
Melatonin prevents EAAC1 deletion‐induced retinal ganglion cell degeneration by inhibiting apoptosis and senescence	7
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An independent comparison of the Novolytix salivary melatonin radioimmunoassay with the new Novolytix salivary melatonin enzyme‐linked immunosorbent assay	6
Adrenergic Agonists Activate Transcriptional Activity in Immortalized Neuronal Cells From the Mouse Suprachiasmatic Nucleus	6
Sleep Deprivation Induces Gut Damage via Ferroptosis	6
Circadian light/dark cycle reversal exacerbates the progression of chronic kidney disease in mice	6
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Melatonin‐mediated malic enzyme 2 orchestrates mitochondrial fusion and respiratory functions to promote odontoblastic differentiation during tooth development	6
Safety and efficacy of melatonin supplementation as an add‐on treatment for infantile epileptic spasms syndrome: A randomized, placebo‐controlled, double‐blind trial	6
Skeletal Phenotyping of Period‐1‐Deficient Melatonin‐Proficient Mice	6
Melatonin suppresses the metastatic potential of osteoblastic prostate cancers by inhibiting integrin α2β1 expression	6
Effect of melatonin cream on acute radiation dermatitis in patients with primary breast cancer: A double‐blind, randomized, placebo‐controlled trial	6
Supraspinal melatonin MT2 receptor agonism alleviates pain via a neural circuit that recruits mu opioid receptors	6
OPA1 Mediated Fatty Acid β‐Oxidation in Hepatocyte: The Novel Insight for Melatonin Attenuated Apoptosis in Concanavalin A Induced Acute Liver Injury	6
Modulations in irradiance directed at melanopsin, but not cone photoreceptors, reliably alter electrophysiological activity in the suprachiasmatic nucleus and circadian behaviour in mice	6
Daytime rest: Association with 24‐h rest–activity cycles, circadian timing and cognition in older adults	6
Melatonin alleviates myocardial dysfunction through inhibition of endothelial‐to‐mesenchymal transition via the NF‐κB pathway	6
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Melatonin inhibits the stemness of head and neck squamous cell carcinoma by modulating HA synthesis via the FOSL1/HAS3 axis	5
Melatonin Inhibits ET‐1 Production to Break Crosstalk Between Prostate Cancer and Bone Cells: Implication for Osteoblastic Bone Metastasis Treatment	5
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Melatonin protects inner retinal neurons of newborn mice after hypoxia‐ischemia	5
N1‐Acetyl‐5‐methoxykynuramine, which decreases in the hippocampus with aging, improves long‐term memory via CaMKII/CREB phosphorylation	5
The role of MEK1/2 and MEK5 in melatonin‐mediated actions on osteoblastogenesis, osteoclastogenesis, bone microarchitecture, biomechanics, and bone formation	5
Melatonin inhibits seed germination by crosstalk with abscisic acid, gibberellin, and auxin in Arabidopsis	5
From gestational chronodisruption to noncommunicable diseases: Pathophysiological mechanisms of programming of adult diseases, and the potential therapeutic role of melatonin	4
Dose assessment of melatonin in sepsis (DAMSEL2) study: Pharmacokinetics of two doses of oral melatonin in patients with sepsis	4
Correction to “Effects of melatonin on fatty liver disease: The role of NR4A1/DNA‐PKcs/p53 pathway, mitochondrial fission, and mitophagy”	4
Correction to “Melatonin mediates selenium‐induced tolerance to cadmium stress in tomato plants”	4
Melatonin improves cholestatic liver disease via the gut‐liver axis	4
ArylalkylamineN‐acetyltransferase (AANAT): Blue light induction, nuclear translocation, and potential role in the survival of chicken retina neuronal cells	4
Correction to “Melatonin suppresses platelet activation and function against cardiac ischemia/reperfusion injury via PPARγ/FUNDC1/mitophagy pathways”	4
Activation of melatonin receptor 1 by CRISPR‐Cas9 activator ameliorates cognitive deficits in an Alzheimer's disease mouse model	4

RETRACTION: Melatonin Inhibits the Expression of the Inducible Isoform of Nitric Oxide Synthase and Nuclear Factor Kappa B Activation in Rat Skeletal Muscle	4
Melatonin treatment improves ventricular conduction via upregulation of Nav1.5 channel proteins and sodium current in the normal rat heart	4
3‐Month Melatonin Supplementation to Reduce Brain Oxidative Stress and Improve Sleep in Mild Cognitive Impairment: A Randomised Controlled Feasibility Trial	3
From Pineal to Biological Rhythms Through Melatonin	3
Melatonin in energy control: Circadian time‐giver and homeostatic monitor	3
Predicting melatonin suppression by light in humans: Unifying photoreceptor‐based equivalent daylight illuminances, spectral composition, timing and duration of light exposure	3
Melatonin delays dark‐induced leaf senescence by inducing miR171b expression in tomato	3
Melatonin improves skin barrier damage caused by sleep restriction through gut microbiota	3
Melatonin suppresses tumor proliferation and metastasis by targeting GATA2 in endometrial cancer	3
Exogenous melatonin decreases circadian misalignment and body weight among early types	3
Melatonin synthesis genes N‐acetylserotonin methyltransferases evolved into caffeic acid O‐methyltransferases and both assisted in plant terrestrialization	3
Sex‐Specific Methylomic and Transcriptomic Responses of the Avian Pineal Gland to Unpredictable Illumination Patterns	3
Dysregulation of the Suprachiasmatic Nucleus Disturbs the Circadian Rhythm and Aggravates Epileptic Seizures by Inducing Hippocampal GABAergic Dysfunction in C57BL/6 Mice	3
Light Environment of Arctic Solstices is Coupled With Melatonin Phase‐Amplitude Changes and Decline of Metabolic Health	2
Melatonin induces apoptotic cell death through Bim stabilization by Sp1‐mediated OTUD1 upregulation	2
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Gut microbially produced tryptophan metabolite melatonin ameliorates osteoporosis via modulating SCFA and TMAO metabolism	2
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Melatonin suppression by light involves different retinal photoreceptors in young and older adults	2