OOIR: Observatory of International Research

Papers

(The H4-Index of Biomedicine & Pharmacotherapy is 100. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
Editorial Board	402
Editorial Board	355
Retraction notice to “MiR-155–5p promotes oral cancer progression by targeting chromatin remodeling gene ARID2” [Biomed. Pharmacother. 122 (2020) 109696]	343
Recent advances on European research in the field of "Biomedicine & Pharmacotherapy"	317
Corrigendum to: ’Protective effect of vaginal resveratrol administration on joint tissues in ovariectomized rats: Targeting mTOR and сaspase 3’ [Biomed. Pharmacother. (2023) 115176/165]	300
Corrigendum to “CRKL knockdown promotes in vitro proliferation, migration and invasion, in vivo tumor malignancy and lymph node metastasis of murine hepatocarcinoma Hca-P cells” [Biomed. Pharmacother.	296
Editorial Board	290
Retraction notice to "Helenalin from Centipeda minima ameliorates acute hepatic injury by protecting mitochondria function, activating Nrf2 pathway and inhibiting NF-κB activation" [Biomed. Pharmacoth	289
The use of a selective, nontoxic dual-acting peptide for breast cancer patients with brain metastasis	286
Cortex periplocae modulates the gut microbiota to restrict colitis and colitis-associated colorectal cancer via suppression of pathogenic Th17 cells	286
Dysregulation of miR-411 in cancer: Causative factor for pathogenesis, diagnosis and prognosis	270
Disruption of IL-18 signaling via engineered IL-18BP biologics alleviates experimental cholestatic liver disease	234
A new IRES-mediated truncated Cx32 isoform inhibits global mRNA translation to suppress glioblastoma	231
Synergic effect of bone marrow derived mesenchymal stem cells and differentiated keratinocytes-like cells with a novel cellulose and collagen nanoscaffold on wound healing in rats	225
Rejuvenating hepatic tumor microenvironment immunity with a phosphatidylserine-targeting small molecule drug conjugate	218
The role of ubiquitin-specific peptidases in glioma progression	213
Efficient generation of a CYP3A4-T2A-luciferase knock-in HepaRG subclone and its optimized differentiation	206
CXCL12 inhibits hair growth through CXCR4	202
Retraction notice to “Piperine alleviates lipopolysaccharide-induced inflammatory injury by down-regulating microRNA-127 in murine chondrogenic ATDC5 cells” [Biomed. Pharmacother. 103 (2018) 947–954]	200
Retraction notice to “Alkannin protects human renal proximal tubular epithelial cells from LPS-induced inflammatory injury by regulation of microRNA-210” [Biomed. Pharmacother. 108 (2018) 1679–1685]	187
Seroprevalence of SARS-CoV-2-specific antibodies and vaccination-related adverse events in systemic lupus erythematosus and rheumatoid arthritis	184
Ethanolic extract of Pyrrosia lingua (Thunb.) Farw. ameliorates OVX-induced bone loss and RANKL-induced osteoclastogenesis	175
Egg white protein hydrolysate ameliorated sepsis-induced inflammatory injuries in kidney and liver based on metabolomics analysis	173
Expression of concern: MicroRNA-370 protects against myocardial ischemia/reperfusion injury in mice following sevoflurane anesthetic preconditioning through PLIN5- dependent PPAR signaling pathway [Bi	169
Expression of concern: MicroRNA-497 promotes proliferation and inhibits apoptosis of cardiomyocytes through the downregulation of Mfn2 in a mouse model of myocardial ischemia-reperfusion injury [Biome	165

Expression of concern: miR-539 enhances chemosensitivity to cisplatin in non-small cell lung cancer by targeting DCLK1 [Biomedicine & Pharmacotherapy 106 (2018) 1072–1081]	164
Curcumin modulates multiple cell death, matrix metalloproteinase activation and cardiac protein release in susceptible and resistant Plasmodium berghei-infected mice	163
Patient-derived tumor models in cancer research: Evaluation of the oncostatic effects of melatonin	160
Editorial Board	160
Retraction notice to “Effects of Artesunate on chondrocyte proliferation, apoptosis and autophagy through the PI3K/AKT/mTOR signaling pathway in rat models with rheumatoid arthritis” [Biomed. Pharmaco	160
Emerging roles of miR-145 in gastrointestinal cancers: A new paradigm	157
PBMCs gene expression signature of advanced cirrhosis with high risk for clinically significant portal hypertension in HIV/HCV coinfected patients: A cross-control study	156
Electroencephalographic profile of Salvia amarissima Ortega and amarisolide A in the absence and presence of PTZ-induced seizures in mice	154
Potential roles of exosomes in the initiation and metastatic progression of lung cancer	153
Editorial Board	153
Endoplasmic reticulum stress in intestinal microecology: A controller of antineoplastic drug-related cardiovascular toxicity	152
Editorial Board	152
Retraction notice to “CircPIP5K1A activates KRT80 and PI3K/AKT pathway to promote gastric cancer development through sponging miR-671-5p” [Biomed. Pharmacother. 126 (2020) 109941]	151
Preventive nutritional supplementation with furan fatty acid in a DIO mouse model increases muscle mass and reduces metabolic disorders	149
Between therapy effect and false-positive result in animal experimentation	147
Molecular insight into arrhythmogenic cardiomyopathy caused by DSG2 mutations	147
Resveratrol improves hepatic ischemia-reperfusion injury by inhibiting neutrophils via the ERK signaling pathway	146
Hyperbranched polymer dots enhance hair follicle regeneration via Wnt/β-catenin activation: A drug-free nanozyme-based approach to hair growth therapy	142
Corrigendum to “Hesperidin ameliorates impairment in hippocampal neural stem cells related to apoptosis induced by methotrexate in adult rats” [Biomed. Pharmacother. 166 (2023), 115329]	141
Corrigendum to “I-CBP112 declines overexpression of ATP-binding cassette transporters and sensitized drug-resistant MDA-MB-231 and A549 cell lines to chemotherapy drugs” [Biomed. Pharmacother. 168 (20	141
Effects of emulsified and non-emulsified palm tocotrienol on bone and joint health in ovariectomised rats with monosodium iodoacetate-induced osteoarthritis	140
Corrigendum to “Secretory products of DPSC mitigate inflammatory effects in microglial cells by targeting MAPK pathway” Biomed. Pharmacother. 170(2024) 115971	140
Erythropoietin-mediated IL-17 F attenuates sepsis-induced gut microbiota dysbiosis and barrier dysfunction	138
Retraction notice to “Overexpression of macrophage stimulating 1 enhances the anti-tumor effects of IL-24 in esophageal cancer via inhibiting ERK-Mfn2 signaling-dependent mitophagy” [Biomed. Pharmacot	137
ACT001 inhibits primary central nervous system lymphoma tumor growth by enhancing the anti-tumor effect of T cells	137
The anti-fibrotic efficacy of adelmidrol depends on hepatic PPARγ levels	136
Lactobacillus Casei-fermented Amomum Xanthioides Mitigates non-alcoholic fatty liver disease in a high-fat diet mice model	135
Drug repurposing for neurodegenerative diseases using Zebrafish behavioral profiles	135
Therapeutic strategies targeting synovial cells to treat osteoarthritis	135
Glioblastoma targeting by water-soluble hypericin derivate HHL-PVP and photodynamic tumour killing	135
Beneficial effects of carvedilol modulating potassium channels on the control of glucose	133
Glycogen synthase kinase-3: A potential immunotherapeutic target in tumor microenvironment	133
Unraveling the molecular and immunological landscape: Exploring signaling pathways in osteoporosis	132
Advance on combination therapy strategies based on biomedical nanotechnology induced ferroptosis for cancer therapeutics	130
Oxaliplatin reversibly and differentially affects electrogenic activity of small IB4(+) of male and female rat sensory neurons	129
Therapeutic effects of CGS21680, a selective A2A receptor agonist, via BDNF-related pathways in R106W mutation Rett syndrome model	128
The significance of dysregulated serine metabolism in depression	126
The role of the serotonergic system in atropine’s anti-myopic effects	124
Discovery of a novel NUAK1 inhibitor against pancreatic cancer	124
Kefir peptides mitigate L-NAME-induced preeclampsia in rats through modulating hypertension and endothelial dysfunction	123
Discovery of a synthetic taiwaniaquinoid with potent in vitro and in vivo antitumor activity against breast cancer cells	121
Soluble guanylate cyclase stimulation improves cardiac function and mitochondrial activity in a rat model of early-stage heart failure with preserved ejection fraction	121
Phytochemicals targeting mitophagy: Therapeutic opportunities and prospects for treating Alzheimer’s disease	118
Urolithin A conjugation with NSAIDs inhibits its glucuronidation and maintains improvement of Caco-2 monolayers' barrier function	118
Sesquiterpene lactones as potential therapeutic agents against Naegleria fowleri	118
Carminic acid mitigates fructose-triggered hepatic steatosis by inhibition of oxidative stress and inflammatory reaction	117
FM19G11-loaded nanoparticles modulate energetic status and production of reactive oxygen species in myoblasts from ALS mice	117
Neural crest-derived cells possess differentiation potential to keratinocytes in the process of wound healing	117
919 granules improve postpartum depression through the regulation of abnormal peripheral blood IL-1β	114
Hydroxyurea protects against diabetic cardiomyopathy by inhibiting inflammation and apoptosis	114

Drug repositioning: Identification of potent inhibitors of NS3 protease and NS5 RdRp for control of DENV infection	114
The interaction between ETS transcription factor family members and microRNAs: A novel approach to cancer therapy	114
Anti-inflammatory and inflammasome-modulating effects of Jinmu-Tang, a Korean traditional medicine: Integrated network pharmacology and experimental evaluation in a DSS-induced colitis model	113
Normobaric oxygen treatment in a depression-like model in male and female rats – Safety, behavioral benefits, and modulation of serotonin and inflammatory markers	113
Sphingolipid metabolism and insulin resistance – Does cannabigerol protect against experimental colitis induced by high-fat high-sucrose diet?	112
Bridging predictions with experimental reality: In vitro evaluation of phenolic natural products as SARS-CoV-2 exoribonuclease inhibitors	112
The three dicaffeoylquinic acids of Erigeron breviscapus strengthen anticoagulation of warfarin in rats: Implications in pharmacokinetics and pharmacodynamics	112
Self-delivery nanodrug to manipulate tumor microenvironment for boosting photodynamic cancer immunotherapy	111
In silico and pharmacological study of N,S-acetal juglone derivatives as inhibitors of the P2X7 receptor-promoted in vitro and in vivo inflammatory response	110
A comprehensive review on pharmacological, toxicity, and pharmacokinetic properties of phillygenin: Current landscape and future perspectives	110
Protective effect of esculentoside A against myocardial infarction via targeting C-X-C motif chemokine receptor 2	108
The melatonergic agonist agomelatine ameliorates high fat diet-induced obesity in mice through the modulation of the gut microbiome	108
Optimizing mesenchymal stromal cells priming strategies for tailored effects on the secretome	108
Notoginsenoside Ft1 induces lysosomal cell death and apoptosis by inhibiting the PI3K/AKT/mTOR pathway in hepatocellular carcinoma	108
Sephin1 enhances integrated stress response and autophagy to alleviate myocardial ischemia-reperfusion injury in mice	107
“Aducanumab” making a comeback in Alzheimer’s disease: An old wine in a new bottle	107
Colchicine: Emerging therapeutic effects on atrial fibrillation by alleviating myocardial fibrosis in a rat model	107
Effective-component compatibility of Bufei Yishen formula alleviates chronic obstructive pulmonary disease inflammation by regulating GSK3β-mediated NLRP3 inflammasome activation	106
In situ administration of temperature-sensitive hydrogel composite loading paclitaxel microspheres and cisplatin for the treatment of melanoma	105
Ferroptosis: A novel therapeutic target of natural products against doxorubicin-induced cardiotoxicity	104
Salvadora persica attenuates DMBA-induced mammary cancer through downregulation oxidative stress, estrogen receptor expression and proliferation and augmenting apoptosis	104
Artesunate promoted anti-tumor immunity and overcame EGFR-TKI resistance in non-small-cell lung cancer by enhancing oncogenic TAZ degradation	104
Basic research on curcumin in cervical cancer: Progress and perspectives	103
Induction of JAK2/STAT3 pathway contributes to protective effects of different therapeutics against myocardial ischemia/reperfusion	102
Monitoring of lamotrigine concentrations in mothers, colostrum, and breastfed newborns during the early postpartum period	101
Whole-exome sequencing reveals genetic variations in humans with differential sensitivity to sevoflurane：A prospective observational study	100