Biomedicine & Pharmacotherapy

Article	Citations
Antidiabetic and antioxidant potential of total extract and supernatant fraction of the roots of Anogeissus leiocarpus in HFD-fed and Streptozocin -induced diabetic rats	510
Hippocampus kuda protein hydrolysate improves male reproductive dysfunction in diabetic rats	490
Mitochondrial metabolism regulated macrophage phenotype in myocardial infarction	344
Corrigendum to “Riluzole ameliorates learning and memory deficits in Aβ25–35-induced rat model of Alzheimer’s disease and is independent of cholinoceptor activation” [Biomedicine & Pharmacotherapy	266
Dysbiosis and diabetic foot ulcers: A metabolic perspective of Staphylococcus aureus infection	254
Isoliquiritigenin alleviates SLC7A11-mediated efferocytosis inhibition to promote wounds healing in diabetes	253
Kefir peptides mitigate L-NAME-induced preeclampsia in rats through modulating hypertension and endothelial dysfunction	226
Pharmacological differences in postoperative cutaneous sensitivity, pain at rest, and movement-induced pain in laparotomized mice	217
Potential mechanisms of Treponema pallidum breaching the blood-brain barrier	209
Editorial Board	206
Intradermal administration of novel particulate Chlamydia trachomatis vaccine candidates drives protective immune responses	206
Developing a novel P-glycoprotein inhibitor and pairing it with oral paclitaxel liposomes for enhanced cancer therapy	204
Oridonin alleviates cigarette smoke-induced nasal polyp formation by promoting autophagy	202
Novel [18F]FPG-interleukin-2 conjugate for monitoring immune checkpoint therapy with positron emission tomography	201
PAD inhibition downregulates the cellular fibrotic behavior of senescent myofibroblasts derived from dilated cardiomyopathy	201
Triptolide-induced acute liver injury and its mechanism with estradiol in regulating macrophage-mediated inflammation and hepatocyte function	200
Retraction notice to "Physcion Induces apoptosis through triggering endoplasmic reticulum stress in hepatocellular carcinoma"[Biomed. Pharmacother. 99(2018) 894–903]	198
Retraction notice to "Overexpression of FADD and Caspase-8 inhibits proliferation and promotes apoptosis of human glioblastoma cells" [Biomed. Pharmacother. 93 (2017) 1–7]	189
Retraction notice to "Possible mechanisms involved in the protective effects of chrysin against lead-induced cognitive decline: An in vivo study in a rat model" [Biomed. Pharmacother. 157 (2022) 11401	173
Retraction notice to “Overexpression of macrophage stimulating 1 enhances the anti-tumor effects of IL-24 in esophageal cancer via inhibiting ERK-Mfn2 signaling-dependent mitophagy” [Biomed. Pharmacot	173
Retraction notice to "Ameliorative potential of sitagliptin and/or resveratrol on experimentally-induced clear cell renal cell carcinoma" [Biomed. Pharmacother. 97 (2017) 667–674	161
Expression of concern: Matrine inhibits hypoxia/reoxygenation-induced apoptosis of cardiac microvascular endothelial cells in rats via the JAK2/STAT3 signaling pathway [Biomedicine & Pharmacothera	159
Retraction notice to "Helenalin from Centipeda minima ameliorates acute hepatic injury by protecting mitochondria function, activating Nrf2 pathway and inhibiting NF-κB activation" [Biomed. Pharmacoth	158
Retraction notice to “Piperine alleviates lipopolysaccharide-induced inflammatory injury by down-regulating microRNA-127 in murine chondrogenic ATDC5 cells” [Biomed. Pharmacother. 103 (2018) 947–954]	157
Retraction notice to “Alkannin protects human renal proximal tubular epithelial cells from LPS-induced inflammatory injury by regulation of microRNA-210” [Biomed. Pharmacother. 108 (2018) 1679–1685]	153

Retraction notice to "Emodin attenuates apoptosis and inflammation induced by LPS through up-regulating lncRNA TUG1 in murine chondrogenic ATDC5 cells" [Biomed. Pharmacother. 103 (2018) 897 – 902]	152
Retraction notice to “Long non-coding RNA TTN-AS1 promotes tumorigenesis of ovarian cancer through modulating the miR-139–5p/ROCK2 axis” [Biomed. Pharmacother. 125 (2020) 109882]	151
Expression of concern: miR-539 enhances chemosensitivity to cisplatin in non-small cell lung cancer by targeting DCLK1 [Biomedicine & Pharmacotherapy 106 (2018) 1072–1081]	150
Retraction notice to "Tripterine alleviates LPS-induced inflammatory injury by up-regulation of miR-146a in HaCaT cells" [Biomed. Pharmacother. 105 (2018) 798–804]	149
Retraction notice to “Effects of Artesunate on chondrocyte proliferation, apoptosis and autophagy through the PI3K/AKT/mTOR signaling pathway in rat models with rheumatoid arthritis” [Biomed. Pharmaco	146
Expression of concern: Repression of long non-coding RNA MEG3 restores nerve growth and alleviates neurological impairment after cerebral ischemia-reperfusion injury in a rat model. [Biomedicine &	143
Expression of concern: MicroRNA-497 promotes proliferation and inhibits apoptosis of cardiomyocytes through the downregulation of Mfn2 in a mouse model of myocardial ischemia-reperfusion injury [Biome	138
Retraction notice to “Long non-coding RNA LINC00525 promotes the non-small cell lung cancer progression by targeting miR-338-3p/IRS2 axis” [Biomed. Pharmacother. 124 (2020) 109858]	134
Expression of concern: Long noncoding RNA PVT1 enhances the viability and invasion of papillary thyroid carcinoma cells by functioning as ceRNA of microRNA-30a through mediating expression of insulin	133
Retraction notice to “Matrine inhibits hypoxia/reoxygenation-induced apoptosis of cardiac microvascular endothelial cells in rats via the JAK2/STAT3 signaling pathway” [Biomed. Pharmacother. 106 (2018	133
Expression of concern: MicroRNA-370 protects against myocardial ischemia/reperfusion injury in mice following sevoflurane anesthetic preconditioning through PLIN5- dependent PPAR signaling pathway [Bi	124
A novel potent class I HDAC inhibitor reverses the STAT4/p66Shc apoptotic defect in B cells from chronic lymphocytic leukemia patients	122
Prescriptive behavior of non-vitamin K oral anticoagulants in patients affected by atrial fibrillation in general practice	121
Effects of sacubitril/valsartan on cardiac remodeling in heart failure with reduced ejection fraction: An integrated study of molecular biomarkers and imaging techniques	119
8-Oxypalmatine, a novel oxidative metabolite of palmatine, exhibits superior anti-colitis effect via regulating Nrf2 and NLRP3 inflammasome	119
Radiopaque hydrogel-in-liposomes towards theranostic applications for malignant tumors	119
Oxaliplatin reversibly and differentially affects electrogenic activity of small IB4(+) of male and female rat sensory neurons	117
Therapeutic effects of CGS21680, a selective A2A receptor agonist, via BDNF-related pathways in R106W mutation Rett syndrome model	117
MITOCDNB DECREASES PLATELET ACTIVATION THROUGH ITS SELECTIVE ACTION ON MITOCHONDRIAL THIOREDOXIN REDUCTASE	117
Illudin S inhibits p53-Mdm2 interaction for anticancer efficacy in colorectal cancer	116
HEBE: A novel chimeric chronokine for ameliorating memory deficits in Alzheimer’s disease	115
Towards dual function of autophagy in breast cancer: A potent regulator of tumor progression and therapy response	114
Patient-derived tumor models in cancer research: Evaluation of the oncostatic effects of melatonin	113
Gentianella acuta improves TAC-induced cardiac remodelling by regulating the Notch and PI3K/Akt/FOXO1/3 pathways	112
Advances in lacrimal gland organoid development: Techniques and therapeutic applications	111
Status of research on natural protein tyrosine phosphatase 1B inhibitors as potential antidiabetic agents: Update	111
Melatonin regulates microglial M1/M2 polarization via AMPKα2-mediated mitophagy in attenuating sepsis-associated encephalopathy	111
Tacrolimus regulates extracellular vesicle secretion from T cells via autophagy-lysosomal pathway	109
Helminth-derived molecules improve 5-fluorouracil treatment on experimental colon tumorigenesis	109
YL-109 attenuates sepsis-associated multiple organ injury through inhibiting the ERK/AP-1 axis and pyroptosis by upregulating CHIP	107
Hypotensive drugs mitigate the high-sodium diet-induced pro-inflammatory activation of mouse macrophages in vivo	106
Cardiovascular outcomes and molecular targets for the cardiac effects of Sodium-Glucose Cotransporter 2 Inhibitors: A systematic review	105
Mitochondrial dynamics dysfunction: Unraveling the hidden link to depression	105
Combined in vivo effect of N-acylethanolamine-hydrolyzing acid amidase and glycogen synthase kinase-3β inhibition to treat multiple sclerosis	104
Nature-inspired substituted 3-(imidazol-2-yl) morpholines targeting human topoisomerase IIα: Dynophore-derived discovery	104
Formyl peptide enhances cancer immunotherapy by activating antitumoral neutrophils, and T cells	104
CaMKII activity and metabolic imbalance-related neurological diseases: Focus on vascular dysfunction, synaptic plasticity, amyloid beta accumulation, and lipid metabolism	102
NADPH and NAC synergistically inhibits chronic ocular hypertension-induced neurodegeneration and neuroinflammation through regulating p38/MAPK pathway and peroxidation	102
A multifunctional antibody fusion protein 57103 targeting CD24, IL-4R, and αvβ3 for treating cancer and regulating the tumor microenvironment	101
Low-dose cadmium induces lymphangiogenesis through activation of the STAT3 signaling pathway	100
Novel insight into the role of A-kinase anchoring proteins (AKAPs) in ischemic stroke and therapeutic potentials	100
Ketamine administration causes cognitive impairment by destroying the circulation function of the glymphatic system	100
Targeting KEAP1-mediated IKKβ degradation strategy for colitis-associated colorectal carcinogenesis: The potential of xanthohumol	99
Development of alginate and alginate sulfate/polycaprolactone nanoparticles for growth factor delivery in wound healing therapy	99
Retraction notice to “Cilostazol protects mice against myocardium ischemic/reperfusion injury by activating a PPAR?/JAK2/STAT3 pathway” [Biomed. Pharmacother. 94 (2017) 995–1001]	98
Corrigendum to “Advances in lacrimal gland organoid development: Techniques and therapeutic applications” [Biomed. Pharmacother. 183 (2025) 117870]	98
Evaluation of the effect of Hashimoto's Thyroiditis on fatty acids involved in inflammation in the thyroid tissue	97
Retraction notice to “MiR-155–5p promotes oral cancer progression by targeting chromatin remodeling gene ARID2” [Biomed. Pharmacother. 122 (2020) 109696]	97
Ibogalogs decrease neuropathic pain in mice through a mechanism involving crosstalk between 5-HT2A and mGlu2 receptors	96
Thiopurine S-methyltransferase – An important intersection of drug-drug interactions in thiopurine treatment	94

1-benzyl-6-nitro-4-phenyl-4-(methoxycarbonyl)-2(1H)-pyridinone, a novel pirfenidone derivative, alleviate hepatic fibrosis through T cells	94
Response of Alzheimer's disease-like triple transgenic 3x-Tg mice to experimental migraine evoked by nitroglycerin	94
Bryophyllum pinnatum modulation of signaling pathways relevant for preterm labor in human myometrial cells	93
Unveiling lactylation modification: A new hope for cancer treatment	91
Contribution of human organic anion transporter 3-mediated transport of a major linezolid metabolite, PNU-142586, in linezolid-induced thrombocytopenia	91
Right ventricular dysfunction following surgical repair of tetralogy of Fallot: Molecular pathways and therapeutic prospects	91
RETRACTED: mPEG-b-P(Glu-co-Phe) nanoparticles increase gastric retention time and gastric ulcer treatment efficacy of 20(S)-ginsenoside Rg3	90
Current status of superoxide dismutase 2 on oral disease progression by supervision of ROS	89
Phytochemicals targeting lncRNAs: A novel direction for neuroprotection in neurological disorders	88
Cisplatin-loaded gold nanoshells mediate chemo-photothermal therapy against primary and distal lung cancers growth	88
3,5-Dicaffeoylquinic acid attenuates microglial activation-mediated inflammatory pain by enhancing autophagy through the suppression of MCP3/JAK2/STAT3 signaling	87
Acetyl-L-carnitine and/or liposomal co-enzyme Q10 prevent propionic acid-induced neurotoxicity by modulating oxidative tissue injury, inflammation, and ALDH1A1-RA-RARα signaling in rats	87
Harnessing exosomes as cutting-edge drug delivery systems for revolutionary osteoarthritis therapy	86
AS1411 aptamer-functionalized exosomes in the targeted delivery of doxorubicin in fighting colorectal cancer	86
Mirogabalin, a novel ligand for α2δ subunit of voltage-gated calcium channels, improves cognitive impairments in repeated intramuscular acidic saline injection model rats, an experimental model of fib	86
Delta-tocotrienol disrupts PD-L1 glycosylation and reverses PD-L1-mediated immune suppression	86
HOXB9 a miR-122–5p regulated gene, suppressed the anticancer effects of brusatol by upregulating SCD1 expression in melanoma	85
In silico drug repurposing in COVID-19: A network-based analysis	85
Whole-exome sequencing reveals genetic variations in humans with differential sensitivity to sevoflurane：A prospective observational study	85
The pharmacokinetic property and pharmacological activity of acteoside: A review	85
Synthesis of cinnamic acid ester derivatives with antiproliferative and antimetastatic activities on murine melanoma cells	85
Plumbagin reduction by thioredoxin reductase 1 possesses synergy effects with GLUT1 inhibitor on KEAP1-mutant NSCLC cells	84
Pleckstrin Homology [PH] domain, structure, mechanism, and contribution to human disease	84
Role of ghrelin hormone in the development of alcohol-associated liver disease	84
New insights from the single-cell level: Tumor associated macrophages heterogeneity and personalized therapy	84
Lung cancer chemotherapy using nanoparticles: Enhanced target ability of redox-responsive and pH-sensitive cisplatin prodrug and paclitaxel	84
Glucose oxidase and MnO2 functionalized liposome for catalytic radiosensitization enhanced synergistic breast cancer therapy	83
Positive or negative anteromedial cortical support of unstable pertrochanteric femoral fractures: A finite element analysis study	83
Resveratrol improves hepatic ischemia-reperfusion injury by inhibiting neutrophils via the ERK signaling pathway	83
State-of-the-art cerium nanoparticles as promising agents against human viral infections	82
PCSK9 inhibitors revisited: Effectiveness and safety of PCSK9 inhibitors in a real-life Spanish cohort	82
Quercetin ameliorates oxidative stress‑induced cell apoptosis of seminal vesicles via activating Nrf2 in type 1 diabetic rats	82
Jiangzhi granule attenuates non-alcoholic steatohepatitis through modulating bile acid in mice fed high-fat vitamin D deficiency diet	82
The emerging role of noncoding RNAs in the Hedgehog signaling pathway in cancer	82
Recent advances in magnetic nanocarriers for tumor treatment	81
4-Acetylantroquinonol B ameliorates nonalcoholic steatohepatitis by suppression of ER stress and NLRP3 inflammasome activation	80
Type-2 diabetic rat heart: The effect of kolaviron on mTOR-1, P70S60K, PKC-α, NF-kB, SOD-2, NRF-2, eNOS, AKT-1, ACE, and P38 MAPK gene expression profile	80
Chemical, biological and protein-receptor binding profiling of Bauhinia scandens L. stems provide new insights into the management of pain, inflammation, pyrexia and thrombosis	80
The emerging diagnostic and therapeutic roles of small nucleolar RNAs in lung diseases	79
Pipecolic acid mitigates ferroptosis in diabetic retinopathy by regulating GPX4-YAP signaling	79
Curcumin modulates multiple cell death, matrix metalloproteinase activation and cardiac protein release in susceptible and resistant Plasmodium berghei-infected mice	79
Hydrogel-coated needles prevent puncture site bleeding in arteriovenous fistula and arteriovenous grafts in rats	78
Epigenetically suppressed tumor cell intrinsic STING promotes tumor immune escape	78
Necroptosis in Alzheimer’s disease: Potential therapeutic target	78
Analytical validation of a novel UHPLC-MS/MS method for 19 antibiotics quantification in plasma: Implementation in a LC-MS/MS Kit	78
SGLT2 inhibitor-empagliflozin treatment ameliorates diabetic retinopathy manifestations and exerts protective effects associated with augmenting branched chain amino acids catabolism and transportatio	78
Measuring the oral bioavailability of protein hydrolysates derived from food sources: A critical review of current bioassays	78
Retraction notice to “Alkannin inhibits proliferation, migration and invasion of hepatocellular carcinoma cells via regulation of miR-92a” [Biomed. Pharmacother. 114 (2019) 108782]	77
Retraction notice to “Sinomenine inhibits proliferation, migration, invasion and promotes apoptosis of prostate cancer cells by regulation of miR-23a” [Biomed. Pharmacother. 112 (2019) 108592]	77
Umbilical cord mesenchymal stem cells overexpressing CXCR7 facilitate treatment of ARDS-associated pulmonary fibrosis via inhibition of Notch/Jag1 mediated by the Wnt/β-catenin pathway	77
Molecular targets for the management of gastrointestinal cancer using melatonin, a natural endogenous body hormone	76
Expression of Concern: “Lycium barbarum polysaccharides protects H9c2 cells from hypoxia-induced injury by down-regulation of miR-122” [Biomed. Pharmacother. 110 (2019) 20–28]	76
Carminic acid mitigates fructose-triggered hepatic steatosis by inhibition of oxidative stress and inflammatory reaction	76
Retraction notice to "Astragaloside protects oxygen and glucose deprivation induced injury by regulation of microRNA-21 in retinal ganglion cell line RGC-5" [Biomed. Pharmacother. 109 (2018) 1826–1833	76
OAT3 mediates methotrexate resistance in the treatment of rheumatoid arthritis	75
Role of circular RNAs in colorectal tumor microenvironment	75
Nitric oxide in kidney transplantation	75
Antimicrobial activity of the membrane-active compound nTZDpa is enhanced at low pH	75
Psoralen suppresses the phosphorylation of amyloid precursor protein (APP) to inhibit myelosuppression	75
Editorial Board	75
Disorders of the central nervous system: Insights from Notch and Nrf2 signaling	74
Egg white protein hydrolysate ameliorated sepsis-induced inflammatory injuries in kidney and liver based on metabolomics analysis	74
The melatonergic agonist agomelatine ameliorates high fat diet-induced obesity in mice through the modulation of the gut microbiome	74
Natural compounds efficacy in Ophthalmic Diseases: A new twist impacting ferroptosis	74
Design, synthesis and mechanism of action of novel 1,9-disubstituted β-carboline derivatives as antitumor agents	73
Comparison of the effects of ketoprofen and ketoprofen lysine salt on the Wistar rats’ nervous system, kidneys and liver after ethyl alcohol intoxication	73
Effect of St. John’s wort extract Ze 117 on the lateral mobility of β1-adrenergic receptors in C6 cells	73
The expression and function of miR-622 in a variety of tumors	73
Between therapy effect and false-positive result in animal experimentation	72
Editorial Board	72
Bias-force guided simulations combined with experimental validations towards GPR17 modulators identification	72
Galanin N-terminal fragment (1−15) reduces alcohol seeking and alcohol relapse in rats: Involvement of mesocorticolimbic system	72
Unveiling the role of ferroptosis-associated exosomal non-coding RNAs in cancer pathogenesis	71
Non-coding RNAs in metabolic reprogramming of bone and soft tissue sarcoma: Fundamental mechanism and clinical implication	71
Cultured versus freshly isolated adipose-derived stem cells in improvement of the histopathological outcomes in HCL-induced cystitis in a rat model	71
Regulatory activities of Warbugia ugandensis ethanolic extracts on colorectal cancer-specific genome expression dose-dependently	71
In vivo and in vitro per se effect evaluation of Polycaprolactone and Eudragit® RS100-based nanoparticles	71
The BR2 peptide associated with 2-aminoethyl dihydrogen phosphate is a formulation with antiproliferative potential for a triple-negative breast cancer model	71
Ticagrelor regulates the differentiation of MDSCs after acute myocardial infarction to reduce cardiac injury	71
Repurposing an atherosclerosis targeting peptide for tumor imaging	71

Safety evaluation of the mouse TCRα - transduced T cell product in preclinical models in vivo and in vitro	71
Editorial Board	70
Synergistic interactions of cytarabine-adavosertib in leukemic cell lines proliferation and metabolomic endpoints	70
Identification and analysis of a selective DYRK1A inhibitor	70
Albendazole ameliorates inflammatory response in a rat model of acute mesenteric ischemia reperfusion injury	70
Lychee seed polyphenol ameliorates DR via inhibiting inflammasome/apoptosis and angiogenesis in hRECs and db/db mice	70
In vivo and in vitro evidence for growth hormone-like bioactivity of Rhizoma Anemarrhenae extract	70
Bmal1 and Gut-lung axis in SARS-CoV-2 infection: New insight into the effects of melatonin on COVID-19 patients?	70
Interaction between non-coding RNAs and JNK in human disorders	70
Therapeutic efficacy of 3,4-Diaminopyridine phosphate on neuromuscular junction in Pompe disease	69
cep-1 mediated the mitohormesis effect of Shengmai formula in regulating Caenorhabditis elegans lifespan	69
Telomerase reverse transcriptase restores pancreatic microcirculation profiles and attenuates endothelial dysfunction by inhibiting mitochondrial superoxide production: A potential target for acute pa	68
Already low drug dose antagonism of the renin-angiotensin aldosterone system decreases 1-year mortality and rehospitalization in old heart failure patients	68
Ethyl pyruvate supplemented in drinking water ameliorates experimental nonalcoholic steatohepatitis	68
Praeruptorin B inhibits osteoclastogenesis by targeting GSTP1 and impacting on the S-glutathionylation of IKKβ	67
Irbesartan ameliorates chronic mountain sickness in a rat model via the cholesterol metabolism: An iTRAQ -based proteomics analysis	67
Investigations of the antipyretic effect and safety of Prasachandaeng, a traditional remedy from Thailand national list of essential medicines	67
Recent advances in the screening methods of NPC1L1 inhibitors	67
Comprehensive polyoxypregnane glycosides report in Caralluma quadrangula using UPLC–ESI–Q–TOF and their antioxidant effects in human plasma	66
Associations between intestinal microbiota, fecal properties, and dietary fiber conditions: The Japanese traditional medicine Junchoto ameliorates dietary fiber deficit–induced constipation with F/B r	66
Bioinformatics study of the potential therapeutic effects of ginsenoside Rf in reversing nonalcoholic fatty liver disease	66
Lentinula edodes extract increases goblet cell number and Muc2 expression in an intestinal inflammatory model of Trichinella spiralis infection	66
Editorial Board	66
Teicoplanin derivatives block spike protein mediated viral entry as pan-SARS-CoV-2 inhibitors	65
Targeting hypoxia-related metabolism molecules: How to improve tumour immune and clinical treatment?	65
The methodological quality and clinical applicability of meta-analyses on probiotics in 2020: A cross-sectional study	65
Carbamazepine and carbamazepine-epoxide concentrations in mothers, colostrum, and breastfed newborns: Comparison with concentrations determined during delivery and in the mature milk period	65
Improvement of chronic non-bacterial prostatitis by Jiedu Huoxue decoction through inhibiting TGF-β/SMAD signaling pathway	65
Mesenchymal stem cell conditioned medium alleviates acute lung injury through KGF-mediated regulation of epithelial sodium channels	65
Plant homeodomain-finger protein 5A: A key player in cancer progression	65
Phytochemicals as new therapeutic candidates simultaneously stimulate proliferation and counteract senescence of stem cells	65
Renoprotective and therapeutic effects of newly water, ethanol, and butanol ginseng fractions in hypertensive and chronic kidney disease with L-NAME	65
A preliminary study on the association of tamoxifen, endoxifen, and 4-hydroxytamoxifen with blood lipids in patients with breast cancer	65
IRGM/Irgm1 deficiency inhibits neutrophil-platelet interactions and thrombosis in experimental atherosclerosis and arterial injury	65
A novel estrogen-targeted PEGylated liposome co-delivery oxaliplatin and paclitaxel for the treatment of ovarian cancer	64
Anticancer potential of Marina Crystal Minerals (MCM) against the growth of murine mammary adenocarcinoma cells in vivo	64
The Locus Coeruleus – Noradrenaline system: Looking into Alzheimer’s therapeutics with rose coloured glasses	64
Molecular insight into arrhythmogenic cardiomyopathy caused by DSG2 mutations	64
Immunomodulation effect of mesenchymal stem cells in islet transplantation	64
Personalized neoantigen-based T cell therapy triggers cytotoxic lymphocytes expressing polyclonal TCR against metastatic ovarian cancer	64
Sequential rearrangement and stereochemical reorganization to design an antimicrobial peptide with enhanced stability	63
Epigenetic regulation of temozolomide resistance in human cancers with an emphasis on brain tumors: Function of non-coding RNAs	63
Bmal1-knockout mice exhibit reduced cocaine-seeking behaviour and cognitive impairments	63
Supplementation of conventional anti-diabetic therapy with alpha-lipoic acid prevents early development and progression of diabetic nephropathy	63
Effect of the elastin-derived peptides (VGVAPG and VVGPGA) on breast (MCF-7) and lung (A549) cancer cell lines in vitro	62
Pain and agitation treatment in severe dementia patients: The need for Italian Mobilization–Observation–Behavior–Intensity–Dementia (I-MOBID2) pain scale translation, adaptation and validation with ps	62
Comparison of five diarrhea-predominant irritable bowel syndrome (IBS-D) rat models in the brain-gut-microbiota axis	62
Novel cardioprotective mechanism for Empagliflozin in nondiabetic myocardial infarction with acute hyperglycemia	62
Epidemiology, clinical ramifications, and cellular pathogenesis of COVID-19 mRNA-vaccination-induced adverse cardiovascular outcomes: A state-of-the-heart review	61
Alpha-tocopheryl succinate and doxorubicin-loaded liposomes improve drug uptake and tumor accumulation in a murine breast tumor model	61
Editorial Board	61
Potential roles of exosomes in the initiation and metastatic progression of lung cancer	61
The FAAH inhibitor URB597 reduces cocaine intake during conditioned punishment and mitigates cocaine seeking during withdrawal	61
Puerarin improves busulfan-induced disruption of spermatogenesis by inhibiting MAPK pathways	60
Response of human blood platelets to preparations from leaves of Paulownia Clon in Vitro 112	60
Bacterial outer membrane vesicles in cancer: Biogenesis, pathogenesis, and clinical application	60
The anti-fibrotic efficacy of adelmidrol depends on hepatic PPARγ levels	60
miR-33b in human cancer: Mechanistic and clinical perspectives	60
The synergistic mechanism of action of Dajianzhong decoction in conjunction with ketamine in the treatment of depression	60
Caffeic acid alleviates skeletal muscle atrophy in 5/6 nephrectomy rats through the TLR4/MYD88/NF-kB pathway	59
Heme oxygenase-1 inducer hemin does not inhibit SARS-CoV-2 virus infection	59
The role of dynamin-related protein 1 in cerebral ischemia/hypoxia injury	59
Dual therapy with phospholipase and metalloproteinase inhibitors from Sinonatrix annularis alleviated acute kidney and liver injury caused by multiple snake venoms	59
Therapeutic effects of Gambi-jung for the treatment of obesity	59
NAT2 phenotype alters pharmacokinetics of rivaroxaban in healthy volunteers	59
Rosuvastatin and co-enzyme Q10 improve high-fat and high-fructose diet-induced metabolic syndrome in rats via ameliorating inflammatory and oxidative burden	59
In vivo antitumor activity of Euphorbia lathyris ethanol extract in colon cancer models	59
Celastrol exerts antiarrhythmic effects in chronic heart failure via NLRP3/Caspase-1/IL-1β signaling pathway	58
Harnessing nanomedicine for modulating microglial states in the central nervous system disorders: Challenges and opportunities	58
Salidroside improves cognitive function in Parkinson’s disease via Braf-mediated mitogen‑activated protein kinase signaling pathway	58
Phytochemicals targeting mitophagy: Therapeutic opportunities and prospects for treating Alzheimer’s disease	57
Sterol-like drugs potentiate statin-triggered prostate cancer cell death by inhibiting SREBP2 nuclear translocation	57
Intermittent antibiotic treatment accelerated the development of colitis in IL-10 knockout mice	57
High levels of soluble CD73 unveil resistance to BRAF inhibitors in melanoma cells	57
Interval training and Crataegus persica ameliorate diabetic nephropathy via miR-126/Nrf-2 mediated inhibition of stress oxidative in rats with diabetes after myocardial ischemia-reperfusion injury	56
Effect of zinc oxide nanoparticles and ferulic acid on renal ischemia/reperfusion injury: possible underlying mechanisms	56
Sequentially degradable hydrogel-microsphere loaded with doxorubicin and pioglitazone synergistically inhibits cancer stemness of osteosarcoma	56
The RAGE signaling in osteoporosis	56
The immunomodulatory effects of probiotics and azithromycin in dextran sodium sulfate-induced ulcerative colitis in rats via TLR4-NF-κB and p38-MAPK pathway	56
Efficacy of Brazilian green propolis (EPP-AF®) as an adjunct treatment for hospitalized COVID-19 patients: A randomized, controlled clinical trial	56
CDX2 controls genes involved in the metabolism of 5-fluorouracil and is associated with reduced efficacy of chemotherapy in colorectal cancer	56
Cortex periplocae modulates the gut microbiota to restrict colitis and colitis-associated colorectal cancer via suppression of pathogenic Th17 cells	56
Potent CaV3.2 channel inhibitors exert analgesic effects in acute and chronic pain models	56
Electroacupuncture activates angiogenesis by regulating the PI3K/Pten/Thbs1 signaling pathway to promote the browning of adipose tissue in HFD-induced obese mice	55
Tea (Camellia sinensis) ameliorates DSS-induced colitis and liver injury by inhibiting TLR4/NF-κB/NLRP3 inflammasome in mice	55
Imbalance of gut microbiota is involved in the development of chronic obstructive pulmonary disease: A review	55
Multi-omics study reveals associations among neurotransmitter, extracellular vesicle-derived microRNA and psychiatric comorbidities during heroin and methamphetamine withdrawal	55
Granulocyte colony-stimulating factor in reproductive-related disease: Function, regulation and therapeutic effect	55
Ginseng and ginsenosides: Therapeutic potential for sarcopenia	55
Identification of curcumin analogues with anti-seizure potential in vivo using chemical and genetic zebrafish larva seizure models	55
The prospect of combination therapies with the third-generation EGFR-TKIs to overcome the resistance in NSCLC	55
HHLA2 immune-regulatory roles in cancer	55
β-hydroxybutyrate: A crucial therapeutic target for diverse liver diseases	54
Diabetes and hypertension: Pivotal involvement of purinergic signaling	54
Basic research on curcumin in cervical cancer: Progress and perspectives	54