Biomedicine & Pharmacotherapy

Papers
(The median citation count of Biomedicine & Pharmacotherapy is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)
ArticleCitations
Editorial Board493
Glioblastoma targeting by water-soluble hypericin derivate HHL-PVP and photodynamic tumour killing487
Editorial Board400
Editorial Board396
Editorial Board373
Antiseizure effects of Lilii Bulbus on pentylenetetrazol kindling-induced seizures in mice: Involvement of Reelin, Netrin-1, and semaphorin349
Necroptosis in Alzheimer’s disease: Potential therapeutic target330
Retraction notice to "Research progress of indole-fused derivatives as allosteric modulators: Opportunities for drug development" [Biomedicine & Pharmacotherapy 162 (2023) 114574]327
Retraction notice to "Anti-proliferation effects, efficacy of cyasterone in vitro and in vivo and its mechanism" [Biomedicine & Pharmacotherapy 84 (2016) 330-339]317
Retraction notice to “Niosome-based hydrogel of resveratrol for topical applications: An effective therapy for pain related disorder(s)” [Biomedicine & Pharmacotherapy 88 (2017) 480-487]277
Hyperbranched polymer dots enhance hair follicle regeneration via Wnt/β-catenin activation: A drug-free nanozyme-based approach to hair growth therapy257
Streptococcus thermophilus CNCM I-5570 lysate counteracts the aging process in human dermal fibroblast cells by neutralizing harmful free radicals and impacting antioxidant and anti-inflammatory pathw255
Retraction notice to “Overexpression of macrophage stimulating 1 enhances the anti-tumor effects of IL-24 in esophageal cancer via inhibiting ERK-Mfn2 signaling-dependent mitophagy” [Biomed. Pharmacot247
Corrigendum to: ’Protective effect of vaginal resveratrol administration on joint tissues in ovariectomized rats: Targeting mTOR and сaspase 3’ [Biomed. Pharmacother. (2023) 115176/165]247
Retraction notice to "Helenalin from Centipeda minima ameliorates acute hepatic injury by protecting mitochondria function, activating Nrf2 pathway and inhibiting NF-κB activation" [Biomed. Pharmacoth244
Retraction notice to “MiR-155–5p promotes oral cancer progression by targeting chromatin remodeling gene ARID2” [Biomed. Pharmacother. 122 (2020) 109696]230
Corrigendum to “I-CBP112 declines overexpression of ATP-binding cassette transporters and sensitized drug-resistant MDA-MB-231 and A549 cell lines to chemotherapy drugs” [Biomed. Pharmacother. 168 (20214
Corrigendum to “Hesperidin ameliorates impairment in hippocampal neural stem cells related to apoptosis induced by methotrexate in adult rats” [Biomed. Pharmacother. 166 (2023), 115329]207
Retraction notice to “CircPIP5K1A activates KRT80 and PI3K/AKT pathway to promote gastric cancer development through sponging miR-671-5p” [Biomed. Pharmacother. 126 (2020) 109941]206
Tracking Chlamydia – Host interactions and antichlamydial activity in Caenorhabditis elegans200
Therapeutic effects of CGS21680, a selective A2A receptor agonist, via BDNF-related pathways in R106W mutation Rett syndrome model199
Effects of emulsified and non-emulsified palm tocotrienol on bone and joint health in ovariectomised rats with monosodium iodoacetate-induced osteoarthritis194
Discovery of a novel NUAK1 inhibitor against pancreatic cancer193
Corrigendum to “Bufalin alleviates myocardial ischemia-reperfusion injury by targeting PTGR2 to regulate NF-κB mediated inflammation” [Biomed. Pharmacother., 2025 Dec; 193:118895]191
Extract of Jasminum grandiflorum L. alleviates CCl4-induced liver injury by decreasing inflammation, oxidative stress and hepatic CYP2E1 expression in mice185
Efficient generation of a CYP3A4-T2A-luciferase knock-in HepaRG subclone and its optimized differentiation182
Retraction notice to “Alkannin protects human renal proximal tubular epithelial cells from LPS-induced inflammatory injury by regulation of microRNA-210” [Biomed. Pharmacother. 108 (2018) 1679–1685]181
Seroprevalence of SARS-CoV-2-specific antibodies and vaccination-related adverse events in systemic lupus erythematosus and rheumatoid arthritis181
Sildenafil delays bone remodeling of fractured femora in aged mice by reducing the number and activity of osteoclasts within the callus tissue180
Emerging roles of miR-145 in gastrointestinal cancers: A new paradigm180
Notoginsenoside Ft1 induces lysosomal cell death and apoptosis by inhibiting the PI3K/AKT/mTOR pathway in hepatocellular carcinoma176
Expression of concern: MicroRNA-497 promotes proliferation and inhibits apoptosis of cardiomyocytes through the downregulation of Mfn2 in a mouse model of myocardial ischemia-reperfusion injury [Biome174
Expression of concern: miR-539 enhances chemosensitivity to cisplatin in non-small cell lung cancer by targeting DCLK1 [Biomedicine & Pharmacotherapy 106 (2018) 1072–1081]174
Cinnarizine dissolving microneedles against microwave-induced brain injury168
A phytotherapic blend immunity-6™ inhibits myeloid leukemic cells 2 activation involving purinergic signaling165
Expression of concern: MicroRNA-370 protects against myocardial ischemia/reperfusion injury in mice following sevoflurane anesthetic preconditioning through PLIN5- dependent PPAR signaling pathway [Bi165
Effects of cPIP2 peptide and rosuvastatin on TLR4 signaling and cardiac remodeling in an acute myocardial infarction model165
Editorial Board163
Phenolic zingerone nanoparticles impede cell cycle progression to compete against human urothelial carcinoma163
Breaking the vicious cycle: Targeting the NLRP3 inflammasome for treating sepsis-associated encephalopathy162
Injectable Gel-PEG hydrogels as promising delivery system for intravitreal PACAP release: Novel therapeutics for unilateral common carotid artery occlusion induced retinal ischemia161
Colchicine: Emerging therapeutic effects on atrial fibrillation by alleviating myocardial fibrosis in a rat model158
A combined transcriptomics and proteomics approach to reveal the mechanism of AEE relieving hyperlipidemia in ApoE-/- mice156
Unveiling the role of ferroptosis-associated exosomal non-coding RNAs in cancer pathogenesis155
Elucidating cuproptosis in metabolic dysfunction-associated steatotic liver disease155
Celastrol exerts antiarrhythmic effects in chronic heart failure via NLRP3/Caspase-1/IL-1β signaling pathway154
Resveratrol improves hepatic ischemia-reperfusion injury by inhibiting neutrophils via the ERK signaling pathway154
Endoplasmic reticulum stress in intestinal microecology: A controller of antineoplastic drug-related cardiovascular toxicity154
Soluble guanylate cyclase stimulation improves cardiac function and mitochondrial activity in a rat model of early-stage heart failure with preserved ejection fraction153
Simple ammonium salt and sigma-1 receptor ligand dipentylammonium provides neuroprotective effects in cell culture and Caenorhabditis elegans models of Alzheimer's disease153
Clofazimine: A journey of a drug147
Physiological and transcriptional profiling of surfactin exerted antifungal effect against Candida albicans145
Microbiota-derived short chain fatty acids: Their role and mechanisms in viral infections144
Corrigendum to “Secretory products of DPSC mitigate inflammatory effects in microglial cells by targeting MAPK pathway” Biomed. Pharmacother. 170(2024) 115971143
The interaction between ETS transcription factor family members and microRNAs: A novel approach to cancer therapy143
Scutellarin enhances anti-tumor immune responses by reducing TNFR2-expressing CD4+Foxp3+ regulatory T cells142
Drug repositioning: Identification of potent inhibitors of NS3 protease and NS5 RdRp for control of DENV infection142
Rejuvenating hepatic tumor microenvironment immunity with a phosphatidylserine-targeting small molecule drug conjugate139
Monitoring of lamotrigine concentrations in mothers, colostrum, and breastfed newborns during the early postpartum period139
CircRNA: An emerging star in the progression of glioma139
Role of long noncoding RNAs in pathological cardiac remodeling after myocardial infarction: An emerging insight into molecular mechanisms and therapeutic potential138
Lactobacillus Casei-fermented Amomum Xanthioides Mitigates non-alcoholic fatty liver disease in a high-fat diet mice model138
Electroencephalographic profile of Salvia amarissima Ortega and amarisolide A in the absence and presence of PTZ-induced seizures in mice137
AG5 is a potent non-steroidal anti-inflammatory and immune regulator that preserves innate immunity136
Multi-omics study reveals associations among neurotransmitter, extracellular vesicle-derived microRNA and psychiatric comorbidities during heroin and methamphetamine withdrawal135
The significance of dysregulated serine metabolism in depression133
Areca catechu L. ameliorates chronic unpredictable mild stress-induced depression behavior in rats by the promotion of the BDNF signaling pathway132
T helper 17 (Th17) cell responses to the gut microbiota in human diseases131
Cannabidiol promotes fine-tuning of natural killer and monocytic cells subsets as well as cytokine storm during chikungunya virus exposure in vitro: Insights for putative therapeutic interventions131
Molecular insight into arrhythmogenic cardiomyopathy caused by DSG2 mutations130
The prospect of combination therapies with the third-generation EGFR-TKIs to overcome the resistance in NSCLC129
Basic research on curcumin in cervical cancer: Progress and perspectives128
Puerarin: a potential natural neuroprotective agent for neurological disorders128
Retraction notice to “Effects of Artesunate on chondrocyte proliferation, apoptosis and autophagy through the PI3K/AKT/mTOR signaling pathway in rat models with rheumatoid arthritis” [Biomed. Pharmaco128
In silico and pharmacological study of N,S-acetal juglone derivatives as inhibitors of the P2X7 receptor-promoted in vitro and in vivo inflammatory response127
Targeting hypoxia-related metabolism molecules: How to improve tumour immune and clinical treatment?126
Editorial Board125
The use of a selective, nontoxic dual-acting peptide for breast cancer patients with brain metastasis123
Role of epigenetics in the regulation of skin aging and geroprotective intervention: A new sight122
Protective effect of esculentoside A against myocardial infarction via targeting C-X-C motif chemokine receptor 2121
919 granules improve postpartum depression through the regulation of abnormal peripheral blood IL-1β120
The anti-fibrotic efficacy of adelmidrol depends on hepatic PPARγ levels119
The FAAH inhibitor URB597 reduces cocaine intake during conditioned punishment and mitigates cocaine seeking during withdrawal119
Zhen-Wu-Tang ameliorates lupus nephritis by diminishing renal tissue-resident memory CD8+ T cells via suppressing IL-15/STAT3 pathway119
Erythropoietin-mediated IL-17 F attenuates sepsis-induced gut microbiota dysbiosis and barrier dysfunction118
Impact of tumor suppressor genes inactivation on the multidrug resistance phenotype of hepatocellular carcinoma cells118
Potential roles of exosomes in the initiation and metastatic progression of lung cancer117
Antioxidant effects of Paeoniflorin and relevant molecular mechanisms as related to a variety of diseases: A review117
Recent advances on European research in the field of "Biomedicine & Pharmacotherapy"116
Advance on combination therapy strategies based on biomedical nanotechnology induced ferroptosis for cancer therapeutics115
Self-delivery nanodrug to manipulate tumor microenvironment for boosting photodynamic cancer immunotherapy115
Cuproptosis in cancers: Function and implications from bench to bedside115
Oxaliplatin reversibly and differentially affects electrogenic activity of small IB4(+) of male and female rat sensory neurons114
State of CD8+ T cells in progression from nonalcoholic steatohepatitis to hepatocellular carcinoma: From pathogenesis to immunotherapy114
Role of SARS-COV-2 and ACE2 in the pathophysiology of peripheral vascular diseases114
Targeting mitochondria as a potential therapeutic strategy against chemoresistance in cancer113
Induction of JAK2/STAT3 pathway contributes to protective effects of different therapeutics against myocardial ischemia/reperfusion112
Leveraging knowledge of HDLs major protein ApoA1: Structure, function, mutations, and potential therapeutics111
The AhR/P38 MAPK pathway mediates kynurenine-induced cardiomyocyte damage: The dual role of resveratrol in apoptosis and autophagy111
A new IRES-mediated truncated Cx32 isoform inhibits global mRNA translation to suppress glioblastoma110
Editors Note “Non-coding RNAs-EZH2 regulatory mechanisms in cervical cancer: The current state of knowledge” [Biomed. Pharmacother., 146 (2022) 112123]110
Multi-organ model assessment of neurotoxicity following exposure of liver spheroids to drugs110
Artesunate promoted anti-tumor immunity and overcame EGFR-TKI resistance in non-small-cell lung cancer by enhancing oncogenic TAZ degradation110
Advances in the role and mechanism of miRNA in inflammatory pain110
Polyphenol-enriched Desmodium elegans DC. ameliorate scopolamine-induced amnesia in animal model of Alzheimer’s disease: In Vitro, In Vivo and In Silico approaches110
Unraveling the molecular and immunological landscape: Exploring signaling pathways in osteoporosis109
Granulocyte colony-stimulating factor in reproductive-related disease: Function, regulation and therapeutic effect109
Between therapy effect and false-positive result in animal experimentation108
Polyphyllin I induces ferritinophagy dependent ferroptosis through EZH2 and promotes anti-tumor immunity108
Non-coding RNAs in metabolic reprogramming of bone and soft tissue sarcoma: Fundamental mechanism and clinical implication107
FM19G11-loaded nanoparticles modulate energetic status and production of reactive oxygen species in myoblasts from ALS mice106
Patient-derived tumor models in cancer research: Evaluation of the oncostatic effects of melatonin106
Amifostine loaded lipid-calcium carbonate nanoparticles as an oral drug delivery system for radiation protection106
Synergic effect of bone marrow derived mesenchymal stem cells and differentiated keratinocytes-like cells with a novel cellulose and collagen nanoscaffold on wound healing in rats105
In situ administration of temperature-sensitive hydrogel composite loading paclitaxel microspheres and cisplatin for the treatment of melanoma105
Long non-coding RNAs and exosomal lncRNAs: Potential functions in lung cancer progression, drug resistance and tumor microenvironment remodeling104
Development of alginate and alginate sulfate/polycaprolactone nanoparticles for growth factor delivery in wound healing therapy104
Glycogen synthase kinase-3: A potential immunotherapeutic target in tumor microenvironment104
Preventive nutritional supplementation with furan fatty acid in a DIO mouse model increases muscle mass and reduces metabolic disorders103
Disruption of IL-18 signaling via engineered IL-18BP biologics alleviates experimental cholestatic liver disease102
CXCL12 inhibits hair growth through CXCR4102
Anti-hepatocellular carcinoma activity of the cyclin-dependent kinase inhibitor AT7519102
RETRACTED: Kefir peptides mitigate L-NAME-induced preeclampsia in rats through modulating hypertension and endothelial dysfunction102
NADPH and NAC synergistically inhibits chronic ocular hypertension-induced neurodegeneration and neuroinflammation through regulating p38/MAPK pathway and peroxidation101
PBMCs gene expression signature of advanced cirrhosis with high risk for clinically significant portal hypertension in HIV/HCV coinfected patients: A cross-control study101
Anti-inflammatory and inflammasome-modulating effects of Jinmu-Tang, a Korean traditional medicine: Integrated network pharmacology and experimental evaluation in a DSS-induced colitis model100
Bridging predictions with experimental reality: In vitro evaluation of phenolic natural products as SARS-CoV-2 exoribonuclease inhibitors100
Normobaric oxygen treatment in a depression-like model in male and female rats – Safety, behavioral benefits, and modulation of serotonin and inflammatory markers100
Sphingolipid metabolism and insulin resistance – Does cannabigerol protect against experimental colitis induced by high-fat high-sucrose diet?100
The three dicaffeoylquinic acids of Erigeron breviscapus strengthen anticoagulation of warfarin in rats: Implications in pharmacokinetics and pharmacodynamics98
Corrigendum to “High potency of magnetic iron oxide nanoparticles covered by piroctone olamine against cystic echinococcosis” [Biomed. Pharmacother., 2023 (161) 114536]97
Corrigendum to “Bicyclol ameliorates nonalcoholic fatty liver disease in mice via inhibiting MAPKs and NF-κB signaling pathways” [Biomed. Pharmacother. 141 (2021) 1–12/111874]97
Hedera helix-derived α−hederin (IVL-11) demonstrates both ex vivo and in vivo flukicidal activities against Fasciola hepatica96
Relationship between hepatic lipid accumulation and type 2 diabetes mellitus96
Corrigendum to “Areca catechu L. ameliorates chronic unpredictable mild stress-induced depression behavior in rats by the promotion of the BDNF signaling pathway” [Biomed. Pharmacother. 164 (2023), 1196
Tea (Camellia sinensis) ameliorates DSS-induced colitis and liver injury by inhibiting TLR4/NF-κB/NLRP3 inflammasome in mice95
Combination of rosuvastatin and curcumin outperforms monotherapies in alleviating gentamicin-induced nephrotoxicity, audiotoxicity and vestibulotoxicity in a rat animal model95
Modulating autophagy to boost the antitumor efficacy of TROP2-directed antibody-drug conjugate in pancreatic cancer95
Beneficial effects of carvedilol modulating potassium channels on the control of glucose95
Imbalance of gut microbiota is involved in the development of chronic obstructive pulmonary disease: A review95
Drug repurposing for neurodegenerative diseases using Zebrafish behavioral profiles94
Mechanical stress abnormalities promote chondrocyte senescence - The pathogenesis of knee osteoarthritis94
The role of the serotonergic system in atropine’s anti-myopic effects94
Sephin1 enhances integrated stress response and autophagy to alleviate myocardial ischemia-reperfusion injury in mice94
Urolithin A conjugation with NSAIDs inhibits its glucuronidation and maintains improvement of Caco-2 monolayers' barrier function94
Retraction notice to "Effect of nano silver on gastroprotective activity against ethanol-induced stomach ulcer in rats" [Biomedicine & Pharmacotherapy 154 (2022) 113550]93
Retraction notice to "Loss of Raf kinase inhibitor protein is associated with malignant progression in hepatic fibrosis" [Biomedicine & Pharmacotherapy 82 (2016) 669-676]93
Retraction notice to “Taraxerol, a pentacyclic triterpenoid, from Abroma augusta leaf attenuates diabetic nephropathy in type 2 diabetic rats” [Biomedicine & Pharmacotherapy 94 (2017) 726-741]92
The impact of curcumin on migraine: A comprehensive review92
Oral administration of Bifidobacterium longum and Bifidobacterium infantis ameliorates cefcapene pivoxil-induced attenuation of anti-programmed cell death protein-1 antibody action in mice92
Venetoclax in adult acute myeloid leukemia91
Discovery of a synthetic taiwaniaquinoid with potent in vitro and in vivo antitumor activity against breast cancer cells90
Caffeic acid phenethyl ester inhibits MDA-MB-231 cell proliferation in inflammatory microenvironment by suppressing glycolysis and lipid metabolism90
Corrigendum to “CRKL knockdown promotes in vitro proliferation, migration and invasion, in vivo tumor malignancy and lymph node metastasis of murine hepatocarcinoma Hca-P cells” [Biomed. Pharmacother.89
Excess iron intake induced liver injury: The role of gut-liver axis and therapeutic potential89
Si-Ni-San reverses dietary fat absorption defects in a murine model of depression88
Egg white protein hydrolysate ameliorated sepsis-induced inflammatory injuries in kidney and liver based on metabolomics analysis87
Cortex periplocae modulates the gut microbiota to restrict colitis and colitis-associated colorectal cancer via suppression of pathogenic Th17 cells87
Palbociclib promotes the antitumor activity of Venetoclax plus Azacitidine against acute myeloid leukemia87
Hydroxyurea protects against diabetic cardiomyopathy by inhibiting inflammation and apoptosis86
Oral sodium butyrate supplementation ameliorates paclitaxel-induced behavioral and intestinal dysfunction86
The melatonergic agonist agomelatine ameliorates high fat diet-induced obesity in mice through the modulation of the gut microbiome85
Bacterial outer membrane vesicles in cancer: Biogenesis, pathogenesis, and clinical application84
Experimental and approved treatments for skin photosensitivity in individuals with erythropoietic protoporphyria or X-linked protoporphyria: A systematic review84
Retraction notice to "New insight towards development of paclitaxel and docetaxel resistance in cancer cells: EMT as a novel molecular mechanism and therapeutic possibilities" [Biomedicine & Pharm84
The pharmacokinetic property and pharmacological activity of acteoside: A review84
Mechanistic insights and clinical implications of the S100 protein family in breast cancer84
Cytosolic DNA sensing pathway in senescence and aging: Underlying mechanisms and targeted interventions83
Dihydromyricetin treats pulmonary hypertension by modulating CKLF1/CCR5 axis-induced pulmonary vascular cell pyroptosis83
Renal intrinsic cells remodeling in diabetic kidney disease and the regulatory effects of SGLT2 Inhibitors83
Ferroptosis: A novel therapeutic target of natural products against doxorubicin-induced cardiotoxicity83
Therapeutic strategies targeting synovial cells to treat osteoarthritis83
A comprehensive review on pharmacological, toxicity, and pharmacokinetic properties of phillygenin: Current landscape and future perspectives83
Targeting the STAT3 oncogenic pathway: Cancer immunotherapy and drug repurposing82
Optimizing mesenchymal stromal cells priming strategies for tailored effects on the secretome82
Phytochemicals targeting mitophagy: Therapeutic opportunities and prospects for treating Alzheimer’s disease82
Toll-like receptor 4: A potential therapeutic target for multiple human diseases82
Diet-gut microbiota-epigenetics in metabolic diseases: From mechanisms to therapeutics82
ACT001 inhibits primary central nervous system lymphoma tumor growth by enhancing the anti-tumor effect of T cells82
Effective-component compatibility of Bufei Yishen formula alleviates chronic obstructive pulmonary disease inflammation by regulating GSK3β-mediated NLRP3 inflammasome activation82
Medicinal and mechanistic overview of artemisinin in the treatment of human diseases81
Analytical validation of a novel UHPLC-MS/MS method for 19 antibiotics quantification in plasma: Implementation in a LC-MS/MS Kit81
Manipulating TGF-β signaling to optimize immunotherapy for cervical cancer80
The phenolic compounds tyrosol and hydroxytyrosol counteract liver fibrogenesis via the transcriptional modulation of NADPH oxidases and oxidative stress-related miRNAs80
Ootheca mantidis mitigates renal fibrosis in mice by the suppression of apoptosis via increasing the gut microbe Akkermansia muciniphila and modulating glutamine metabolism80
Celastrol has beneficial effects on pulmonary hypertension associated with bronchopulmonary dysplasia: Preclinical study outcomes80
Riboceine and N-acetylcysteine protect normal prostate cells from chemotherapy-induced oxidative stress while selectively modulating the cytotoxicity of methotrexate and docetaxel in prostate (PC-3) a79
Anti-photoaging effect and mechanism of flexible liposomes co-loaded with apigenin and doxycycline79
Managing metabolic diseases: The roles and therapeutic prospects of herb-derived polysaccharides79
Retraction notice to “Healing potential of Spirulina platensis for skin wounds by modulating bFGF, VEGF, TGF-ß1 and α-SMA genes expression targeting angiogenesis and scar tissue formation in the rat m79
Editorial Board79
Transplantation of adipose-derived mesenchymal stem cells ameliorates acute hepatic injury caused by nonsteroidal anti-inflammatory drug diclofenac sodium in female rats79
Amazonian medicinal plants efficiently inactivate Herpes and Chikungunya viruses79
Synthesis and characterization of new P2X7 receptor antagonists as antitumor agents78
Propofol pretreatment alleviates mast cell degranulation by inhibiting SOC to protect the myocardium from ischemia–reperfusion injury78
Hecogenin and its derivates: A pharmacology review77
Interferon signature predicts chemotherapy resistance in acute myeloid leukaemia77
ANGPTL3 vital role in different kidney diseases. Current knowledge and future perspectives77
Modified Zn-MOF multifunctional nanoparticles for combination therapy of DN and exploratory study of the nephroprotective effect77
The neuroimmune mechanism of pain induced depression in psoriatic arthritis and future directions77
Febuxostat alleviate metabolic dysfunction-associated steatohepatitis in rat model via targeting inflammation, cell death, and intestinal barrier dysfunction76
Corrigendum to “Assessment of dose-response relationship of 5-fluorouracil to murine intestinal injury” [Biomed. Pharmacother. 106 (2018) 910–916]76
Ursodeoxycholic acid ameliorates cell migration retarded by the SARS-CoV-2 spike protein in BEAS-2B human bronchial epithelial cells76
Magnetoresponsive liposomes applications in nanomedicine: A comprehensive review76
Design and synthesis of nucleotidyl lipids and their application in the targeted delivery of siG12D for pancreatic cancer therapy75
Epigenetics of sarcopenia: Insights into mechanisms and interventions for healthy muscle aging74
The effects of Cannabis sativa and cannabinoids on the inhibition of pancreatic lipase – An enzyme involved in obesity74
Design and synthesis of 3,4-seco-lupane triterpene derivatives to resist myocardial ischemia-reperfusion injury by inhibiting oxidative stress-mediated mitochondrial dysfunction via the PI3K/AKT/HIF-174
Dipeptidyl peptidase-4 inhibitor linagliptin reduces inflammatory response, ameliorates tissue edema formation, and improves survival in severe sepsis73
Revolutionizing cancer treatment: The power of dendritic cell-based vaccines in immunotherapy73
Biomedicine and pharmacotherapeutic effectiveness of combinatorial atorvastatin and quercetin on diabetic nephropathy: An in vitro study72
Mechanistic insights into the potential role of dietary polyphenols and their nanoformulation in the management of Alzheimer’s disease72
Musashi inhibitor Ro 08–2750 attenuates triple-negative breast cancer cell proliferation and migration and acts as a novel chemo- and radiosensitizer72
Long non-coding RNAs as pathophysiological regulators, therapeutic targets and novel extracellular vesicle biomarkers for the diagnosis of inflammatory bowel disease71
The immune activity of selective estrogen receptor modulators is gene and macrophage subtype-specific yet converges on Il1b downregulation71
Investigation of the cardioprotective effects of Momordica charantia in the isoproterenol-induced myocardial infarction model in rats71
Substituted indole derivatives as UNC-51-like kinase 1 inhibitors: Design, synthesis and anti-hepatocellular carcinoma activity71
Deapioplatycodin D promotes cell senescence induced by P21 through the mediation of incomplete mitophagy via BNIP3L71
Retraction notice to "miR-217 represses TGF-β1-induced airway smooth muscle cell proliferation and migration through targeting ZEB1 " [Biomed. Pharmacother. 108 (2018) 27–35]70
Inhibition of autophagy and RIP1/RIP3/MLKL-mediated necroptosis by edaravone attenuates blood spinal cord barrier disruption following spinal cord injury70
Protective effect of vaginal resveratrol administration on joint tissues in ovariectomized rats: Targeting mTOR and сaspase 370
Systemic cytokines inhibition with Imp7 siRNA nanoparticle ameliorates gut injury in a mouse model of ventilator-induced lung injury70
Triciribine attenuates pathological neovascularization and vascular permeability in a mouse model of proliferative retinopathy69
Preclinical animal study of electrospun poly (l-lactide-co-caprolactone) and formulated porcine fibrinogen for full-thickness diabetic wound regeneration69
Baicalin ameliorates multidrug-resistant Pseudomonas aeruginosa induced pulmonary inflammation in rat via arginine biosynthesis69
Naotaifang formula attenuates OGD/R-induced inflammation and ferroptosis by regulating microglial M1/M2 polarization through BMP6/SMADs signaling pathway69
A novel GRK2 inhibitor alleviates experimental arthritis through restraining Th17 cell differentiation69
Possible implication of estrogenic compounds on heart disease in menopausal women69
Nanobody-based CAR T cells targeting intracellular tumor antigens68
The effect of lipid metabolism on cuproptosis-inducing cancer therapy68
Therapeutic potential of Curcuma oil and its terpenoids in gynecological cancers68
Lenalidomide attenuates IMQ-induced inflammation in a mouse model of psoriasis68
Gilteritinib reverses ABCB1-mediated multidrug resistance: Preclinical in vitro and animal investigations68
The hepatoprotective effect of aminoguanidine in acute liver injury caused by CCl4 in rats68
LCN2: Versatile players in breast cancer68
Hesperidin ameliorates benign prostatic hyperplasia by attenuating cell proliferation, inflammatory response, and epithelial-mesenchymal transition via the TGF-β1/Smad signaling pathway67
Fucoidan from Cladosiphon okamuranus enhances antioxidant activity and prevents reproductive dysfunction in polystyrene microplastic-induced male rats67
Synergistic effects of fucoidan from Undaria pinnatifida and grouper peptides on glucocorticoid-induced muscle atrophy via protein turnover modulation67
Tricaprin can prevent the development of AAA by attenuating aortic degeneration67
Urine-derived stem cells: The biomedical research of endothelial and cardiovascular tissue67
Treatment of neovascular age-related macular degeneration within 48 h from diagnosis improves long-term functional outcome67
The role of cyclins in the development and progression of prostate cancer66
Advances in the molecular mechanisms of statins in regulating endothelial nitric oxide bioavailability: Interlocking biology between eNOS activity and L-arginine metabolism66
A clinically translatable 2.5D lung adenocarcinoma organoid platform derived from malignant pleural effusions for precision drug screening and tumor-immune-stromal modeling66
In vitro assessment of pirfenidone anti-fibrotic properties in a humanized 3D bioprinted kidney tubulointerstitium model66
Histamine H3 receptor antagonist/nitric oxide donors as novel promising therapeutic hybrid-tools for glaucoma and retinal neuroprotection66
Examining the pharmacokinetic and pharmacodynamic interaction of N,N-dimethyltryptamine and harmine in healthy volunteers: Α factorial dose-escalation study66
Targeting metabolic syndrome with ALIAmides: A novel multi-mechanistic approach65
Bromophenanthrenequinones as antimicrobial and antibiofilm agents against Staphylococcus aureus65
Safety assessment of the SGLT2 inhibitors empagliflozin, dapagliflozin and canagliflozin during pregnancy: An ex vivo human placenta perfusion and in vitro study65
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