Biomedicine & Pharmacotherapy

Papers
(The TQCC of Biomedicine & Pharmacotherapy is 16. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)
ArticleCitations
The anti-fibrotic efficacy of adelmidrol depends on hepatic PPARγ levels545
Editorial Board303
Editorial Board282
Cortex periplocae modulates the gut microbiota to restrict colitis and colitis-associated colorectal cancer via suppression of pathogenic Th17 cells274
Cervical carcinoma high expressed 1 (CCHE1): An oncogenic lncRNA in diverse neoplasms239
A new IRES-mediated truncated Cx32 isoform inhibits global mRNA translation to suppress glioblastoma234
Whole-exome sequencing reveals genetic variations in humans with differential sensitivity to sevoflurane:A prospective observational study227
Disulfiram and metformin combination anticancer effect reversible partly by antioxidant nitroglycerin and completely by NF-κB activator mebendazole in hamster fibrosarcoma227
Editorial Board220
Egg white protein hydrolysate ameliorated sepsis-induced inflammatory injuries in kidney and liver based on metabolomics analysis220
Editorial Board218
Simple ammonium salt and sigma-1 receptor ligand dipentylammonium provides neuroprotective effects in cell culture and Caenorhabditis elegans models of Alzheimer's disease216
Between therapy effect and false-positive result in animal experimentation216
Corrigendum to “CRKL knockdown promotes in vitro proliferation, migration and invasion, in vivo tumor malignancy and lymph node metastasis of murine hepatocarcinoma Hca-P cells” [Biomed. Pharmacother.214
Corrigendum to: ’Protective effect of vaginal resveratrol administration on joint tissues in ovariectomized rats: Targeting mTOR and сaspase 3’ [Biomed. Pharmacother. (2023) 115176/165]206
Corrigendum to “Secretory products of DPSC mitigate inflammatory effects in microglial cells by targeting MAPK pathway” Biomed. Pharmacother. 170(2024) 115971187
Emerging role of carbon monoxide in intestinal transplantation181
A phytotherapic blend immunity-6™ inhibits myeloid leukemic cells 2 activation involving purinergic signaling181
ACT001 inhibits primary central nervous system lymphoma tumor growth by enhancing the anti-tumor effect of T cells180
Editorial Board176
Renal intrinsic cells remodeling in diabetic kidney disease and the regulatory effects of SGLT2 Inhibitors170
NADPH and NAC synergistically inhibits chronic ocular hypertension-induced neurodegeneration and neuroinflammation through regulating p38/MAPK pathway and peroxidation165
Ethanolic extract of Pyrrosia lingua (Thunb.) Farw. ameliorates OVX-induced bone loss and RANKL-induced osteoclastogenesis165
Retraction notice to “MiR-155–5p promotes oral cancer progression by targeting chromatin remodeling gene ARID2” [Biomed. Pharmacother. 122 (2020) 109696]165
Sephin1 enhances integrated stress response and autophagy to alleviate myocardial ischemia-reperfusion injury in mice162
Silencing tumor-intrinsic CD73 enhances the chemosensitivity of NSCLC and potentiates the anti-tumoral effects of cisplatin: An in vitro study158
Neural crest-derived cells possess differentiation potential to keratinocytes in the process of wound healing158
Rejuvenating hepatic tumor microenvironment immunity with a phosphatidylserine-targeting small molecule drug conjugate157
Tracking Chlamydia – Host interactions and antichlamydial activity in Caenorhabditis elegans151
A combined transcriptomics and proteomics approach to reveal the mechanism of AEE relieving hyperlipidemia in ApoE-/- mice150
Efficient generation of a CYP3A4-T2A-luciferase knock-in HepaRG subclone and its optimized differentiation148
Recent advances on European research in the field of "Biomedicine & Pharmacotherapy"146
Urolithin A conjugation with NSAIDs inhibits its glucuronidation and maintains improvement of Caco-2 monolayers' barrier function143
The interaction between ETS transcription factor family members and microRNAs: A novel approach to cancer therapy142
Expression of concern: miR-539 enhances chemosensitivity to cisplatin in non-small cell lung cancer by targeting DCLK1 [Biomedicine & Pharmacotherapy 106 (2018) 1072–1081]136
Expression of concern: MicroRNA-370 protects against myocardial ischemia/reperfusion injury in mice following sevoflurane anesthetic preconditioning through PLIN5- dependent PPAR signaling pathway [Bi136
Expression of concern: MicroRNA-497 promotes proliferation and inhibits apoptosis of cardiomyocytes through the downregulation of Mfn2 in a mouse model of myocardial ischemia-reperfusion injury [Biome130
Retraction notice to “Alkannin protects human renal proximal tubular epithelial cells from LPS-induced inflammatory injury by regulation of microRNA-210” [Biomed. Pharmacother. 108 (2018) 1679–1685]128
Retraction notice to “Piperine alleviates lipopolysaccharide-induced inflammatory injury by down-regulating microRNA-127 in murine chondrogenic ATDC5 cells” [Biomed. Pharmacother. 103 (2018) 947–954]128
Editorial Board127
Longitudinal stability of molecular alterations and drug response profiles in tumor spheroid cell lines enables reproducible analyses127
Endoplasmic reticulum stress in intestinal microecology: A controller of antineoplastic drug-related cardiovascular toxicity126
Retraction notice to “Effects of Artesunate on chondrocyte proliferation, apoptosis and autophagy through the PI3K/AKT/mTOR signaling pathway in rat models with rheumatoid arthritis” [Biomed. Pharmaco125
Retraction notice to "Helenalin from Centipeda minima ameliorates acute hepatic injury by protecting mitochondria function, activating Nrf2 pathway and inhibiting NF-κB activation" [Biomed. Pharmacoth125
Retraction notice to “Overexpression of macrophage stimulating 1 enhances the anti-tumor effects of IL-24 in esophageal cancer via inhibiting ERK-Mfn2 signaling-dependent mitophagy” [Biomed. Pharmacot125
Albendazole-loaded cubosomes interrupt the ERK1/2-HIF-1α-p300/CREB axis in mice intoxicated with diethylnitrosamine: A new paradigm in drug repurposing for the inhibition of hepatocellular carcinoma p123
Kefir peptides mitigate L-NAME-induced preeclampsia in rats through modulating hypertension and endothelial dysfunction120
Seroprevalence of SARS-CoV-2-specific antibodies and vaccination-related adverse events in systemic lupus erythematosus and rheumatoid arthritis120
Streptococcus thermophilus CNCM I-5570 lysate counteracts the aging process in human dermal fibroblast cells by neutralizing harmful free radicals and impacting antioxidant and anti-inflammatory pathw119
Curcumin modulates multiple cell death, matrix metalloproteinase activation and cardiac protein release in susceptible and resistant Plasmodium berghei-infected mice118
CXCL12 inhibits hair growth through CXCR4116
Beneficial effects of carvedilol modulating potassium channels on the control of glucose114
Colchicine: Emerging therapeutic effects on atrial fibrillation by alleviating myocardial fibrosis in a rat model113
Celastrol exerts antiarrhythmic effects in chronic heart failure via NLRP3/Caspase-1/IL-1β signaling pathway112
Potential roles of exosomes in the initiation and metastatic progression of lung cancer111
Palbociclib promotes the antitumor activity of Venetoclax plus Azacitidine against acute myeloid leukemia111
The prospect of combination therapies with the third-generation EGFR-TKIs to overcome the resistance in NSCLC110
Anti-hepatocellular carcinoma activity of the cyclin-dependent kinase inhibitor AT7519109
Extract of Jasminum grandiflorum L. alleviates CCl4-induced liver injury by decreasing inflammation, oxidative stress and hepatic CYP2E1 expression in mice109
Elucidating cuproptosis in metabolic dysfunction-associated steatotic liver disease109
Targeting hypoxia-related metabolism molecules: How to improve tumour immune and clinical treatment?108
Oral administration of Bifidobacterium longum and Bifidobacterium infantis ameliorates cefcapene pivoxil-induced attenuation of anti-programmed cell death protein-1 antibody action in mice108
Unveiling the role of ferroptosis-associated exosomal non-coding RNAs in cancer pathogenesis107
Multi-organ model assessment of neurotoxicity following exposure of liver spheroids to drugs106
The AhR/P38 MAPK pathway mediates kynurenine-induced cardiomyocyte damage: The dual role of resveratrol in apoptosis and autophagy106
Glioblastoma targeting by water-soluble hypericin derivate HHL-PVP and photodynamic tumour killing105
Synergic effect of bone marrow derived mesenchymal stem cells and differentiated keratinocytes-like cells with a novel cellulose and collagen nanoscaffold on wound healing in rats105
Monitoring of lamotrigine concentrations in mothers, colostrum, and breastfed newborns during the early postpartum period104
The impact of curcumin on migraine: A comprehensive review104
GYY4137 attenuates functional impairment of corpus cavernosum and reduces fibrosis in rats with STZ-induced diabetes by inhibiting the TGF-β1/Smad/CTGF pathway102
Advance on combination therapy strategies based on biomedical nanotechnology induced ferroptosis for cancer therapeutics102
Squalene nanoemulsion reinforces mucosal and immunological fingerprints following intravaginal delivery100
Scutellarin enhances anti-tumor immune responses by reducing TNFR2-expressing CD4+Foxp3+ regulatory T cells99
Caffeic acid phenethyl ester inhibits MDA-MB-231 cell proliferation in inflammatory microenvironment by suppressing glycolysis and lipid metabolism98
Discovery of a novel NUAK1 inhibitor against pancreatic cancer98
Sesquiterpene lactones as potential therapeutic agents against Naegleria fowleri97
Antiseizure effects of Lilii Bulbus on pentylenetetrazol kindling-induced seizures in mice: Involvement of Reelin, Netrin-1, and semaphorin96
Effective-component compatibility of Bufei Yishen formula alleviates chronic obstructive pulmonary disease inflammation by regulating GSK3β-mediated NLRP3 inflammasome activation96
Discovery of a synthetic taiwaniaquinoid with potent in vitro and in vivo antitumor activity against breast cancer cells96
Role of long noncoding RNAs in pathological cardiac remodeling after myocardial infarction: An emerging insight into molecular mechanisms and therapeutic potential95
Non-coding RNAs in metabolic reprogramming of bone and soft tissue sarcoma: Fundamental mechanism and clinical implication95
A comprehensive review on pharmacological, toxicity, and pharmacokinetic properties of phillygenin: Current landscape and future perspectives95
The FAAH inhibitor URB597 reduces cocaine intake during conditioned punishment and mitigates cocaine seeking during withdrawal95
Patient-derived tumor models in cancer research: Evaluation of the oncostatic effects of melatonin94
Disruption of IL-18 signaling via engineered IL-18BP biologics alleviates experimental cholestatic liver disease94
AG5 is a potent non-steroidal anti-inflammatory and immune regulator that preserves innate immunity94
Dysregulation of miR-411 in cancer: Causative factor for pathogenesis, diagnosis and prognosis93
Amifostine loaded lipid-calcium carbonate nanoparticles as an oral drug delivery system for radiation protection93
Tea (Camellia sinensis) ameliorates DSS-induced colitis and liver injury by inhibiting TLR4/NF-κB/NLRP3 inflammasome in mice93
Polyphenol-enriched Desmodium elegans DC. ameliorate scopolamine-induced amnesia in animal model of Alzheimer’s disease: In Vitro, In Vivo and In Silico approaches93
Oxaliplatin reversibly and differentially affects electrogenic activity of small IB4(+) of male and female rat sensory neurons91
Unraveling the molecular and immunological landscape: Exploring signaling pathways in osteoporosis90
Exploring the anticancer effects of standardized extracts of poplar-type propolis: In vitro cytotoxicity toward cancer and normal cell lines90
Role of epigenetics in the regulation of skin aging and geroprotective intervention: A new sight90
The role of ubiquitin-specific peptidases in glioma progression90
Therapeutic effects of CGS21680, a selective A2A receptor agonist, via BDNF-related pathways in R106W mutation Rett syndrome model90
Identification of curcumin analogues with anti-seizure potential in vivo using chemical and genetic zebrafish larva seizure models88
Si-Ni-San reverses dietary fat absorption defects in a murine model of depression88
Dihydromyricetin treats pulmonary hypertension by modulating CKLF1/CCR5 axis-induced pulmonary vascular cell pyroptosis87
Carminic acid mitigates fructose-triggered hepatic steatosis by inhibition of oxidative stress and inflammatory reaction87
Zhen-Wu-Tang ameliorates lupus nephritis by diminishing renal tissue-resident memory CD8+ T cells via suppressing IL-15/STAT3 pathway86
FM19G11-loaded nanoparticles modulate energetic status and production of reactive oxygen species in myoblasts from ALS mice86
Injectable Gel-PEG hydrogels as promising delivery system for intravitreal PACAP release: Novel therapeutics for unilateral common carotid artery occlusion induced retinal ischemia86
919 granules improve postpartum depression through the regulation of abnormal peripheral blood IL-1β86
The use of a selective, nontoxic dual-acting peptide for breast cancer patients with brain metastasis85
Multi-omics study reveals associations among neurotransmitter, extracellular vesicle-derived microRNA and psychiatric comorbidities during heroin and methamphetamine withdrawal85
Areca catechu L. ameliorates chronic unpredictable mild stress-induced depression behavior in rats by the promotion of the BDNF signaling pathway85
Treprostinil reduces mitochondrial injury during rat renal ischemia-reperfusion injury84
A fungus-derived purpactin A as an inhibitor of TMEM16A chloride channels and mucin secretion in airway epithelial cells84
State of CD8+ T cells in progression from nonalcoholic steatohepatitis to hepatocellular carcinoma: From pathogenesis to immunotherapy84
Venetoclax in adult acute myeloid leukemia84
In silico and pharmacological study of N,S-acetal juglone derivatives as inhibitors of the P2X7 receptor-promoted in vitro and in vivo inflammatory response83
Erythropoietin-mediated IL-17 F attenuates sepsis-induced gut microbiota dysbiosis and barrier dysfunction83
Mannosylated polylactic-co-glycolic acid (MN-PLGA) nanoparticles induce potent anti-tumor immunity in murine model of breast cancer83
Efficacy of Brazilian green propolis (EPP-AF®) as an adjunct treatment for hospitalized COVID-19 patients: A randomized, controlled clinical trial83
Medicinal and mechanistic overview of artemisinin in the treatment of human diseases83
The involvement of NLRP3 inflammasome in the treatment of neurodegenerative diseases83
Oral sodium butyrate supplementation ameliorates paclitaxel-induced behavioral and intestinal dysfunction82
Identification of early diagnostic biomarkers via WGCNA in gastric cancer82
The role of the serotonergic system in atropine’s anti-myopic effects81
Ferroptosis: A novel therapeutic target of natural products against doxorubicin-induced cardiotoxicity81
Inclisiran in lipid management: A Literature overview and future perspectives81
Effects of emulsified and non-emulsified palm tocotrienol on bone and joint health in ovariectomised rats with monosodium iodoacetate-induced osteoarthritis81
Sildenafil delays bone remodeling of fractured femora in aged mice by reducing the number and activity of osteoclasts within the callus tissue81
Salvadora persica attenuates DMBA-induced mammary cancer through downregulation oxidative stress, estrogen receptor expression and proliferation and augmenting apoptosis80
Mechanical stress abnormalities promote chondrocyte senescence - The pathogenesis of knee osteoarthritis80
Engineering of the current nucleoside-modified mRNA-LNP vaccines against SARS-CoV-280
Hippocampus kuda protein hydrolysate improves male reproductive dysfunction in diabetic rats80
Emerging roles of miR-145 in gastrointestinal cancers: A new paradigm80
Toll-like receptor 4: A potential therapeutic target for multiple human diseases79
Onion (Allium cepa L.) peels: A review on bioactive compounds and biomedical activities79
Overcoming drug delivery barriers and challenges in topical therapy of atopic dermatitis: A nanotechnological perspective79
RETRACTED: mPEG-b-P(Glu-co-Phe) nanoparticles increase gastric retention time and gastric ulcer treatment efficacy of 20(S)-ginsenoside Rg379
Leveraging knowledge of HDLs major protein ApoA1: Structure, function, mutations, and potential therapeutics79
T helper 17 (Th17) cell responses to the gut microbiota in human diseases79
Targeting the STAT3 oncogenic pathway: Cancer immunotherapy and drug repurposing79
Development of alginate and alginate sulfate/polycaprolactone nanoparticles for growth factor delivery in wound healing therapy79
PBMCs gene expression signature of advanced cirrhosis with high risk for clinically significant portal hypertension in HIV/HCV coinfected patients: A cross-control study79
Cuproptosis in cancers: Function and implications from bench to bedside79
Self-delivery nanodrug to manipulate tumor microenvironment for boosting photodynamic cancer immunotherapy78
Physiological and transcriptional profiling of surfactin exerted antifungal effect against Candida albicans78
Molecular insight into arrhythmogenic cardiomyopathy caused by DSG2 mutations77
Excess iron intake induced liver injury: The role of gut-liver axis and therapeutic potential77
Supplementation of conventional anti-diabetic therapy with alpha-lipoic acid prevents early development and progression of diabetic nephropathy76
Impact of tumor suppressor genes inactivation on the multidrug resistance phenotype of hepatocellular carcinoma cells76
Interleukin-6 in SARS-CoV-2 induced disease: Interactions and therapeutic applications76
Induction of JAK2/STAT3 pathway contributes to protective effects of different therapeutics against myocardial ischemia/reperfusion76
Targeting mitochondria as a potential therapeutic strategy against chemoresistance in cancer75
Withania somnifera (L.) Dunal (Ashwagandha): A comprehensive review on ethnopharmacology, pharmacotherapeutics, biomedicinal and toxicological aspects75
Imbalance of gut microbiota is involved in the development of chronic obstructive pulmonary disease: A review75
Glycogen synthase kinase-3: A potential immunotherapeutic target in tumor microenvironment75
Microbiota-derived short chain fatty acids: Their role and mechanisms in viral infections74
“Aducanumab” making a comeback in Alzheimer’s disease: An old wine in a new bottle74
Parecoxib improves atherosclerotic plaque stability by suppressing inflammation and inhibiting matrix metalloproteinases production74
Modulating autophagy to boost the antitumor efficacy of TROP2-directed antibody-drug conjugate in pancreatic cancer74
Breaking the vicious cycle: Targeting the NLRP3 inflammasome for treating sepsis-associated encephalopathy74
Empagliflozin adjunct with metformin for the inhibition of hepatocellular carcinoma progression: Emerging approach for new application74
Electroencephalographic profile of Salvia amarissima Ortega and amarisolide A in the absence and presence of PTZ-induced seizures in mice73
Resveratrol improves hepatic ischemia-reperfusion injury by inhibiting neutrophils via the ERK signaling pathway73
Bacterial outer membrane vesicles in cancer: Biogenesis, pathogenesis, and clinical application73
Tomato (Solanum lycopersicum L.) seed: A review on bioactives and biomedical activities73
Antioxidant effects of Paeoniflorin and relevant molecular mechanisms as related to a variety of diseases: A review73
Analytical validation of a novel UHPLC-MS/MS method for 19 antibiotics quantification in plasma: Implementation in a LC-MS/MS Kit73
Fluoxetine ameliorates high-fat diet-induced metabolic abnormalities partially via reduced adipose triglyceride lipase-mediated adipocyte lipolysis72
Long non-coding RNAs and exosomal lncRNAs: Potential functions in lung cancer progression, drug resistance and tumor microenvironment remodeling72
The melatonergic agonist agomelatine ameliorates high fat diet-induced obesity in mice through the modulation of the gut microbiome72
The sodium-glucose cotransporter-2 inhibitor Tofogliflozin prevents the progression of nonalcoholic steatohepatitis–associated liver tumors in a novel murine model72
4-thiazolidinone-based derivatives rosiglitazone and pioglitazone affect the expression of antioxidant enzymes in different human cell lines72
The phenolic compounds tyrosol and hydroxytyrosol counteract liver fibrogenesis via the transcriptional modulation of NADPH oxidases and oxidative stress-related miRNAs71
Reactive oxygen species (ROS) in cancer pathogenesis and therapy: An update on the role of ROS in anticancer action of benzophenanthridine alkaloids71
Artesunate promoted anti-tumor immunity and overcame EGFR-TKI resistance in non-small-cell lung cancer by enhancing oncogenic TAZ degradation71
Drug repurposing for neurodegenerative diseases using Zebrafish behavioral profiles71
Mechanistic role of boswellic acids in Alzheimer’s disease: Emphasis on anti-inflammatory properties70
Basic research on curcumin in cervical cancer: Progress and perspectives70
PD-L1 silencing inhibits triple-negative breast cancer development and upregulates T-cell-induced pro-inflammatory cytokines69
Necroptosis in Alzheimer’s disease: Potential therapeutic target69
The pharmacokinetic property and pharmacological activity of acteoside: A review69
Hydroxyurea protects against diabetic cardiomyopathy by inhibiting inflammation and apoptosis68
Corrigendum to “Hesperidin ameliorates impairment in hippocampal neural stem cells related to apoptosis induced by methotrexate in adult rats” [Biomed. Pharmacother. 166 (2023), 115329]68
Corrigendum to “I-CBP112 declines overexpression of ATP-binding cassette transporters and sensitized drug-resistant MDA-MB-231 and A549 cell lines to chemotherapy drugs” [Biomed. Pharmacother. 168 (2068
Experimental and approved treatments for skin photosensitivity in individuals with erythropoietic protoporphyria or X-linked protoporphyria: A systematic review67
Diet-gut microbiota-epigenetics in metabolic diseases: From mechanisms to therapeutics67
Advances in the role and mechanism of miRNA in inflammatory pain67
Protective effect of esculentoside A against myocardial infarction via targeting C-X-C motif chemokine receptor 267
Physalin pool from Physalis angulata L. leaves and physalin D inhibit P2X7 receptor function in vitro and acute lung injury in vivo66
Granulocyte colony-stimulating factor in reproductive-related disease: Function, regulation and therapeutic effect66
Development of vericiguat: The first soluble guanylate cyclase (sGC) stimulator launched for heart failure with reduced ejection fraction (HFrEF)66
Editorial Board65
Preventive nutritional supplementation with furan fatty acid in a DIO mouse model increases muscle mass and reduces metabolic disorders65
Drug repositioning: Identification of potent inhibitors of NS3 protease and NS5 RdRp for control of DENV infection65
Clofazimine: A journey of a drug65
Lactobacillus Casei-fermented Amomum Xanthioides Mitigates non-alcoholic fatty liver disease in a high-fat diet mice model65
Role of SARS-COV-2 and ACE2 in the pathophysiology of peripheral vascular diseases65
Polyphyllin I induces ferritinophagy dependent ferroptosis through EZH2 and promotes anti-tumor immunity65
Cinnarizine dissolving microneedles against microwave-induced brain injury64
Therapeutic targets of neuroprotection and neurorestoration in ischemic stroke: Applications for natural compounds from medicinal herbs64
Puerarin: a potential natural neuroprotective agent for neurological disorders64
Phytochemicals targeting mitophagy: Therapeutic opportunities and prospects for treating Alzheimer’s disease64
CircRNA: An emerging star in the progression of glioma64
Mechanistic insights and perspectives involved in neuroprotective action of quercetin64
Celastrol has beneficial effects on pulmonary hypertension associated with bronchopulmonary dysplasia: Preclinical study outcomes63
Examining the pharmacokinetic and pharmacodynamic interaction of N,N-dimethyltryptamine and harmine in healthy volunteers: Α factorial dose-escalation study63
In situ administration of temperature-sensitive hydrogel composite loading paclitaxel microspheres and cisplatin for the treatment of melanoma63
Modulatory mechanisms of cannabinoids as a window of hope to patients with sleep-related cardiometabolic risk62
ABCB1 genetic polymorphisms affect opioid requirement by altering function of the intestinal P-glycoprotein62
Effects of sodium-glucose cotransporter 2 (SGLT2) inhibitors, dapagliflozin and canagliflozin, on the musculoskeletal system in an experimental model of diabetes induced by high-fat diet and streptozo62
Angiotensin-converting enzyme inhibitors and statins therapies-induced changes in omics profiles in humans and transgenic tau mice62
Editorial Board61
The neuroimmune mechanism of pain induced depression in psoriatic arthritis and future directions61
Editorial Board61
Treatment of neovascular age-related macular degeneration within 48 h from diagnosis improves long-term functional outcome61
De novo interleukin-10 production primed by Lactobacillus sakei CVL-001 amplifies the immunomodulatory abilities of mesenchymal stem cells to alleviate colitis60
Chemical compositions and experimental and computational modeling activity of sea cucumber Holothuria parva ethanolic extract against herpes simplex virus type 160
DA-9805 protects dopaminergic neurons from endoplasmic reticulum stress and inflammation60
Diterpene promptly executes a non-canonical autophagic cell death in doxorubicin-resistant lung cancer60
Activation of renal CSE/H2S pathway by alpha-lipoic acid protects against histological and functional changes in the diabetic kidney60
Advances in precision gene editing for liver fibrosis: From technology to therapeutic applications60
Preclinical toxicological study of long-circulating and fusogenic liposomes co-encapsulating paclitaxel and doxorubicin in synergic ratio60
Gut microbiota as the critical correlation of polycystic ovary syndrome and type 2 diabetes mellitus60
Histamine H3 receptor antagonist/nitric oxide donors as novel promising therapeutic hybrid-tools for glaucoma and retinal neuroprotection59
Jiangu granule ameliorated OVX rats bone loss by modulating gut microbiota-SCFAs-Treg/Th17 axis59
L-NRB alleviates amyotrophic lateral sclerosis by regulating P11-Htr4 signaling pathway59
Polypharmacological profiling across protein target families and cellular pathways using the multiplexed cell-based assay platform safetyProfiler reveals efficacy, potency and side effects of drugs59
Corrigendum to “Hominis Placenta modulates PTSD-like behaviors in SPSS-induced PTSD mice: Regulating energy metabolism and neuronal activity” [Biomed. Pharmacother. 178 (2024) 117243]59
Epac, a positive or negative signaling molecule in cardiovascular diseases59
Dipeptidyl peptidase-4 inhibitor linagliptin reduces inflammatory response, ameliorates tissue edema formation, and improves survival in severe sepsis58
Decoding the role of long non-coding RNAs in periodontitis: A comprehensive review58
Rosuvastatin restores liver tissue-resident NK cell activation in aged mice by improving mitochondrial function58
Current progress of pig models for liver cancer research58
Gilteritinib reverses ABCB1-mediated multidrug resistance: Preclinical in vitro and animal investigations58
Design and synthesis of 3,4-seco-lupane triterpene derivatives to resist myocardial ischemia-reperfusion injury by inhibiting oxidative stress-mediated mitochondrial dysfunction via the PI3K/AKT/HIF-158
Editorial Board58
Dexmedetomidine attenuates lipopolysaccharide-induced renal cell fibrotic phenotypic changes by inhibiting necroinflammation via activating α2-adrenoceptor: A combined randomised animal and in vitro s58
Pharmacokinetics and clinical efficacy of 6′-sialyllactose in patients with GNE myopathy: Randomized pilot trial58
Nano-vitamin C: A promising candidate for therapeutic applications57
Protopanaxadiol ameliorates NAFLD by regulating hepatocyte lipid metabolism through AMPK/SIRT1 signaling pathway57
The role of miR-155 in urologic malignancies57
Fucoidan from Cladosiphon okamuranus enhances antioxidant activity and prevents reproductive dysfunction in polystyrene microplastic-induced male rats57
Nardosinone regulates the slc38a2 gene to alleviate Parkinson's symptoms in rats through the GABAergic synaptic and cAMP pathways57
The effects of Cannabis sativa and cannabinoids on the inhibition of pancreatic lipase – An enzyme involved in obesity57
Anti-photoaging effect and mechanism of flexible liposomes co-loaded with apigenin and doxycycline57
COVID-19 and diabetes: Association intensify risk factors for morbidity and mortality57
Melittin treatment suppressed malignant NSCLC progression through enhancing CTSB-mediated hyperautophagy56
The immune activity of selective estrogen receptor modulators is gene and macrophage subtype-specific yet converges on Il1b downregulation56
Roles of the peroxisome proliferator-activated receptors (PPARs) in the pathogenesis of hepatocellular carcinoma (HCC)56
Overview of blood-brain barrier dysfunction in methamphetamine abuse56
Manipulating TGF-β signaling to optimize immunotherapy for cervical cancer56
The relationship between Listeria infections and host immune responses: Listeriolysin O as a potential target56
YAP-regulated type II alveolar epithelial cell differentiation mediated by human umbilical cord-derived mesenchymal stem cells in acute respiratory distress syndrome56
Future prospects of ketoprofen in improving the safety of the gastric mucosa56
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