Biomedicine & Pharmacotherapy

Papers
(The TQCC of Biomedicine & Pharmacotherapy is 17. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)
ArticleCitations
The anti-fibrotic efficacy of adelmidrol depends on hepatic PPARγ levels347
Editorial Board315
Editorial Board313
A new IRES-mediated truncated Cx32 isoform inhibits global mRNA translation to suppress glioblastoma265
Editorial Board259
Between therapy effect and false-positive result in animal experimentation251
Editorial Board251
Corrigendum to “CRKL knockdown promotes in vitro proliferation, migration and invasion, in vivo tumor malignancy and lymph node metastasis of murine hepatocarcinoma Hca-P cells” [Biomed. Pharmacother.249
Corrigendum to: ’Protective effect of vaginal resveratrol administration on joint tissues in ovariectomized rats: Targeting mTOR and сaspase 3’ [Biomed. Pharmacother. (2023) 115176/165]248
Emerging role of carbon monoxide in intestinal transplantation242
ACT001 inhibits primary central nervous system lymphoma tumor growth by enhancing the anti-tumor effect of T cells230
Editorial Board220
Cervical carcinoma high expressed 1 (CCHE1): An oncogenic lncRNA in diverse neoplasms219
Sildenafil delays bone remodeling of fractured femora in aged mice by reducing the number and activity of osteoclasts within the callus tissue205
Si-Ni-San reverses dietary fat absorption defects in a murine model of depression201
Retraction notice to “MiR-155–5p promotes oral cancer progression by targeting chromatin remodeling gene ARID2” [Biomed. Pharmacother. 122 (2020) 109696]198
Silencing tumor-intrinsic CD73 enhances the chemosensitivity of NSCLC and potentiates the anti-tumoral effects of cisplatin: An in vitro study196
Neural crest-derived cells possess differentiation potential to keratinocytes in the process of wound healing189
Rejuvenating hepatic tumor microenvironment immunity with a phosphatidylserine-targeting small molecule drug conjugate183
A combined transcriptomics and proteomics approach to reveal the mechanism of AEE relieving hyperlipidemia in ApoE-/- mice181
Efficient generation of a CYP3A4-T2A-luciferase knock-in HepaRG subclone and its optimized differentiation179
Recent advances on European research in the field of "Biomedicine & Pharmacotherapy"174
Expression of concern: MicroRNA-370 protects against myocardial ischemia/reperfusion injury in mice following sevoflurane anesthetic preconditioning through PLIN5- dependent PPAR signaling pathway [Bi173
Expression of concern: miR-539 enhances chemosensitivity to cisplatin in non-small cell lung cancer by targeting DCLK1 [Biomedicine & Pharmacotherapy 106 (2018) 1072–1081]172
Expression of concern: MicroRNA-497 promotes proliferation and inhibits apoptosis of cardiomyocytes through the downregulation of Mfn2 in a mouse model of myocardial ischemia-reperfusion injury [Biome168
Retraction notice to “Alkannin protects human renal proximal tubular epithelial cells from LPS-induced inflammatory injury by regulation of microRNA-210” [Biomed. Pharmacother. 108 (2018) 1679–1685]167
Retraction notice to “Piperine alleviates lipopolysaccharide-induced inflammatory injury by down-regulating microRNA-127 in murine chondrogenic ATDC5 cells” [Biomed. Pharmacother. 103 (2018) 947–954]165
Editorial Board161
Endoplasmic reticulum stress in intestinal microecology: A controller of antineoplastic drug-related cardiovascular toxicity153
Retraction notice to "Helenalin from Centipeda minima ameliorates acute hepatic injury by protecting mitochondria function, activating Nrf2 pathway and inhibiting NF-κB activation" [Biomed. Pharmacoth150
Retraction notice to “Effects of Artesunate on chondrocyte proliferation, apoptosis and autophagy through the PI3K/AKT/mTOR signaling pathway in rat models with rheumatoid arthritis” [Biomed. Pharmaco146
Polyphyllin I induces ferritinophagy dependent ferroptosis through EZH2 and promotes anti-tumor immunity143
Editorial Board143
Fluoxetine ameliorates high-fat diet-induced metabolic abnormalities partially via reduced adipose triglyceride lipase-mediated adipocyte lipolysis143
Hydroxyurea protects against diabetic cardiomyopathy by inhibiting inflammation and apoptosis142
Simple ammonium salt and sigma-1 receptor ligand dipentylammonium provides neuroprotective effects in cell culture and Caenorhabditis elegans models of Alzheimer's disease140
Hyperbranched polymer dots enhance hair follicle regeneration via Wnt/β-catenin activation: A drug-free nanozyme-based approach to hair growth therapy139
Corrigendum to “Hesperidin ameliorates impairment in hippocampal neural stem cells related to apoptosis induced by methotrexate in adult rats” [Biomed. Pharmacother. 166 (2023), 115329]139
Corrigendum to “I-CBP112 declines overexpression of ATP-binding cassette transporters and sensitized drug-resistant MDA-MB-231 and A549 cell lines to chemotherapy drugs” [Biomed. Pharmacother. 168 (20136
Experimental and approved treatments for skin photosensitivity in individuals with erythropoietic protoporphyria or X-linked protoporphyria: A systematic review134
CXCL12 inhibits hair growth through CXCR4130
Notoginsenoside Ft1 induces lysosomal cell death and apoptosis by inhibiting the PI3K/AKT/mTOR pathway in hepatocellular carcinoma130
Colchicine: Emerging therapeutic effects on atrial fibrillation by alleviating myocardial fibrosis in a rat model129
Palbociclib promotes the antitumor activity of Venetoclax plus Azacitidine against acute myeloid leukemia129
Potential roles of exosomes in the initiation and metastatic progression of lung cancer128
Targeting hypoxia-related metabolism molecules: How to improve tumour immune and clinical treatment?127
Multi-organ model assessment of neurotoxicity following exposure of liver spheroids to drugs125
The AhR/P38 MAPK pathway mediates kynurenine-induced cardiomyocyte damage: The dual role of resveratrol in apoptosis and autophagy125
Glioblastoma targeting by water-soluble hypericin derivate HHL-PVP and photodynamic tumour killing123
Synergic effect of bone marrow derived mesenchymal stem cells and differentiated keratinocytes-like cells with a novel cellulose and collagen nanoscaffold on wound healing in rats122
Squalene nanoemulsion reinforces mucosal and immunological fingerprints following intravaginal delivery121
Scutellarin enhances anti-tumor immune responses by reducing TNFR2-expressing CD4+Foxp3+ regulatory T cells120
Effective-component compatibility of Bufei Yishen formula alleviates chronic obstructive pulmonary disease inflammation by regulating GSK3β-mediated NLRP3 inflammasome activation119
Discovery of a synthetic taiwaniaquinoid with potent in vitro and in vivo antitumor activity against breast cancer cells119
Non-coding RNAs in metabolic reprogramming of bone and soft tissue sarcoma: Fundamental mechanism and clinical implication118
Cuproptosis in cancers: Function and implications from bench to bedside117
Oral administration of Bifidobacterium longum and Bifidobacterium infantis ameliorates cefcapene pivoxil-induced attenuation of anti-programmed cell death protein-1 antibody action in mice117
Disruption of IL-18 signaling via engineered IL-18BP biologics alleviates experimental cholestatic liver disease117
Erythropoietin-mediated IL-17 F attenuates sepsis-induced gut microbiota dysbiosis and barrier dysfunction115
Breaking the vicious cycle: Targeting the NLRP3 inflammasome for treating sepsis-associated encephalopathy114
Electroencephalographic profile of Salvia amarissima Ortega and amarisolide A in the absence and presence of PTZ-induced seizures in mice113
Amifostine loaded lipid-calcium carbonate nanoparticles as an oral drug delivery system for radiation protection113
Antiseizure effects of Lilii Bulbus on pentylenetetrazol kindling-induced seizures in mice: Involvement of Reelin, Netrin-1, and semaphorin111
Identification of curcumin analogues with anti-seizure potential in vivo using chemical and genetic zebrafish larva seizure models111
The use of a selective, nontoxic dual-acting peptide for breast cancer patients with brain metastasis111
Impact of tumor suppressor genes inactivation on the multidrug resistance phenotype of hepatocellular carcinoma cells110
Patient-derived tumor models in cancer research: Evaluation of the oncostatic effects of melatonin110
The melatonergic agonist agomelatine ameliorates high fat diet-induced obesity in mice through the modulation of the gut microbiome110
FM19G11-loaded nanoparticles modulate energetic status and production of reactive oxygen species in myoblasts from ALS mice109
Oxaliplatin reversibly and differentially affects electrogenic activity of small IB4(+) of male and female rat sensory neurons109
Therapeutic effects of CGS21680, a selective A2A receptor agonist, via BDNF-related pathways in R106W mutation Rett syndrome model109
Zhen-Wu-Tang ameliorates lupus nephritis by diminishing renal tissue-resident memory CD8+ T cells via suppressing IL-15/STAT3 pathway108
919 granules improve postpartum depression through the regulation of abnormal peripheral blood IL-1β108
PBMCs gene expression signature of advanced cirrhosis with high risk for clinically significant portal hypertension in HIV/HCV coinfected patients: A cross-control study107
Emerging roles of miR-145 in gastrointestinal cancers: A new paradigm106
Treprostinil reduces mitochondrial injury during rat renal ischemia-reperfusion injury106
Lactobacillus Casei-fermented Amomum Xanthioides Mitigates non-alcoholic fatty liver disease in a high-fat diet mice model105
Whole-exome sequencing reveals genetic variations in humans with differential sensitivity to sevoflurane:A prospective observational study104
Areca catechu L. ameliorates chronic unpredictable mild stress-induced depression behavior in rats by the promotion of the BDNF signaling pathway104
Self-delivery nanodrug to manipulate tumor microenvironment for boosting photodynamic cancer immunotherapy104
Unveiling the role of ferroptosis-associated exosomal non-coding RNAs in cancer pathogenesis102
Cinnarizine dissolving microneedles against microwave-induced brain injury101
Effects of emulsified and non-emulsified palm tocotrienol on bone and joint health in ovariectomised rats with monosodium iodoacetate-induced osteoarthritis101
Development of alginate and alginate sulfate/polycaprolactone nanoparticles for growth factor delivery in wound healing therapy100
Cortex periplocae modulates the gut microbiota to restrict colitis and colitis-associated colorectal cancer via suppression of pathogenic Th17 cells100
Sesquiterpene lactones as potential therapeutic agents against Naegleria fowleri100
In silico and pharmacological study of N,S-acetal juglone derivatives as inhibitors of the P2X7 receptor-promoted in vitro and in vivo inflammatory response99
Beneficial effects of carvedilol modulating potassium channels on the control of glucose99
Salvadora persica attenuates DMBA-induced mammary cancer through downregulation oxidative stress, estrogen receptor expression and proliferation and augmenting apoptosis99
CircRNA: An emerging star in the progression of glioma99
Urolithin A conjugation with NSAIDs inhibits its glucuronidation and maintains improvement of Caco-2 monolayers' barrier function98
Resveratrol improves hepatic ischemia-reperfusion injury by inhibiting neutrophils via the ERK signaling pathway97
Seroprevalence of SARS-CoV-2-specific antibodies and vaccination-related adverse events in systemic lupus erythematosus and rheumatoid arthritis96
Drug repositioning: Identification of potent inhibitors of NS3 protease and NS5 RdRp for control of DENV infection96
Preventive nutritional supplementation with furan fatty acid in a DIO mouse model increases muscle mass and reduces metabolic disorders96
Physiological and transcriptional profiling of surfactin exerted antifungal effect against Candida albicans95
Protective effect of esculentoside A against myocardial infarction via targeting C-X-C motif chemokine receptor 295
Albendazole-loaded cubosomes interrupt the ERK1/2-HIF-1α-p300/CREB axis in mice intoxicated with diethylnitrosamine: A new paradigm in drug repurposing for the inhibition of hepatocellular carcinoma p95
Longitudinal stability of molecular alterations and drug response profiles in tumor spheroid cell lines enables reproducible analyses95
Caffeic acid phenethyl ester inhibits MDA-MB-231 cell proliferation in inflammatory microenvironment by suppressing glycolysis and lipid metabolism94
Identification of early diagnostic biomarkers via WGCNA in gastric cancer93
The role of ubiquitin-specific peptidases in glioma progression92
Polyphenol-enriched Desmodium elegans DC. ameliorate scopolamine-induced amnesia in animal model of Alzheimer’s disease: In Vitro, In Vivo and In Silico approaches92
Kefir peptides mitigate L-NAME-induced preeclampsia in rats through modulating hypertension and endothelial dysfunction91
Molecular insight into arrhythmogenic cardiomyopathy caused by DSG2 mutations91
Streptococcus thermophilus CNCM I-5570 lysate counteracts the aging process in human dermal fibroblast cells by neutralizing harmful free radicals and impacting antioxidant and anti-inflammatory pathw91
Mechanistic role of boswellic acids in Alzheimer’s disease: Emphasis on anti-inflammatory properties90
Inclisiran in lipid management: A Literature overview and future perspectives90
Optimizing mesenchymal stromal cells priming strategies for tailored effects on the secretome90
The phenolic compounds tyrosol and hydroxytyrosol counteract liver fibrogenesis via the transcriptional modulation of NADPH oxidases and oxidative stress-related miRNAs90
Role of SARS-COV-2 and ACE2 in the pathophysiology of peripheral vascular diseases89
Modulating autophagy to boost the antitumor efficacy of TROP2-directed antibody-drug conjugate in pancreatic cancer89
NADPH and NAC synergistically inhibits chronic ocular hypertension-induced neurodegeneration and neuroinflammation through regulating p38/MAPK pathway and peroxidation89
Therapeutic strategies targeting synovial cells to treat osteoarthritis88
Engineering of the current nucleoside-modified mRNA-LNP vaccines against SARS-CoV-287
Egg white protein hydrolysate ameliorated sepsis-induced inflammatory injuries in kidney and liver based on metabolomics analysis87
Venetoclax in adult acute myeloid leukemia87
Tracking Chlamydia – Host interactions and antichlamydial activity in Caenorhabditis elegans87
Role of epigenetics in the regulation of skin aging and geroprotective intervention: A new sight87
Toll-like receptor 4: A potential therapeutic target for multiple human diseases86
Targeting mitochondria as a potential therapeutic strategy against chemoresistance in cancer86
Necroptosis in Alzheimer’s disease: Potential therapeutic target86
Exploring the anticancer effects of standardized extracts of poplar-type propolis: In vitro cytotoxicity toward cancer and normal cell lines86
“Aducanumab” making a comeback in Alzheimer’s disease: An old wine in a new bottle85
The interaction between ETS transcription factor family members and microRNAs: A novel approach to cancer therapy85
Dysregulation of miR-411 in cancer: Causative factor for pathogenesis, diagnosis and prognosis85
Basic research on curcumin in cervical cancer: Progress and perspectives85
Discovery of a novel NUAK1 inhibitor against pancreatic cancer84
Retraction notice to “CircPIP5K1A activates KRT80 and PI3K/AKT pathway to promote gastric cancer development through sponging miR-671-5p” [Biomed. Pharmacother. 126 (2020) 109941]84
The pharmacokinetic property and pharmacological activity of acteoside: A review84
Interleukin-6 in SARS-CoV-2 induced disease: Interactions and therapeutic applications84
Long non-coding RNAs and exosomal lncRNAs: Potential functions in lung cancer progression, drug resistance and tumor microenvironment remodeling84
Dihydromyricetin treats pulmonary hypertension by modulating CKLF1/CCR5 axis-induced pulmonary vascular cell pyroptosis83
Effects of cPIP2 peptide and rosuvastatin on TLR4 signaling and cardiac remodeling in an acute myocardial infarction model83
Granulocyte colony-stimulating factor in reproductive-related disease: Function, regulation and therapeutic effect83
T helper 17 (Th17) cell responses to the gut microbiota in human diseases82
A phytotherapic blend immunity-6™ inhibits myeloid leukemic cells 2 activation involving purinergic signaling82
Phytochemicals targeting mitophagy: Therapeutic opportunities and prospects for treating Alzheimer’s disease82
Bacterial outer membrane vesicles in cancer: Biogenesis, pathogenesis, and clinical application81
Glycogen synthase kinase-3: A potential immunotherapeutic target in tumor microenvironment81
Imbalance of gut microbiota is involved in the development of chronic obstructive pulmonary disease: A review81
Corrigendum to “Secretory products of DPSC mitigate inflammatory effects in microglial cells by targeting MAPK pathway” Biomed. Pharmacother. 170(2024) 11597180
Supplementation of conventional anti-diabetic therapy with alpha-lipoic acid prevents early development and progression of diabetic nephropathy80
Disulfiram and metformin combination anticancer effect reversible partly by antioxidant nitroglycerin and completely by NF-κB activator mebendazole in hamster fibrosarcoma80
Extract of Jasminum grandiflorum L. alleviates CCl4-induced liver injury by decreasing inflammation, oxidative stress and hepatic CYP2E1 expression in mice80
Empagliflozin adjunct with metformin for the inhibition of hepatocellular carcinoma progression: Emerging approach for new application79
Advances in the role and mechanism of miRNA in inflammatory pain79
In situ administration of temperature-sensitive hydrogel composite loading paclitaxel microspheres and cisplatin for the treatment of melanoma79
The role of the serotonergic system in atropine’s anti-myopic effects79
Antioxidant effects of Paeoniflorin and relevant molecular mechanisms as related to a variety of diseases: A review79
Mannosylated polylactic-co-glycolic acid (MN-PLGA) nanoparticles induce potent anti-tumor immunity in murine model of breast cancer79
Targeting the STAT3 oncogenic pathway: Cancer immunotherapy and drug repurposing79
Analytical validation of a novel UHPLC-MS/MS method for 19 antibiotics quantification in plasma: Implementation in a LC-MS/MS Kit78
Curcumin modulates multiple cell death, matrix metalloproteinase activation and cardiac protein release in susceptible and resistant Plasmodium berghei-infected mice77
Tomato (Solanum lycopersicum L.) seed: A review on bioactives and biomedical activities76
Induction of JAK2/STAT3 pathway contributes to protective effects of different therapeutics against myocardial ischemia/reperfusion76
Celastrol exerts antiarrhythmic effects in chronic heart failure via NLRP3/Caspase-1/IL-1β signaling pathway76
RETRACTED: mPEG-b-P(Glu-co-Phe) nanoparticles increase gastric retention time and gastric ulcer treatment efficacy of 20(S)-ginsenoside Rg376
The prospect of combination therapies with the third-generation EGFR-TKIs to overcome the resistance in NSCLC76
Clofazimine: A journey of a drug76
Carminic acid mitigates fructose-triggered hepatic steatosis by inhibition of oxidative stress and inflammatory reaction75
Artesunate promoted anti-tumor immunity and overcame EGFR-TKI resistance in non-small-cell lung cancer by enhancing oncogenic TAZ degradation75
Overcoming drug delivery barriers and challenges in topical therapy of atopic dermatitis: A nanotechnological perspective75
Reactive oxygen species (ROS) in cancer pathogenesis and therapy: An update on the role of ROS in anticancer action of benzophenanthridine alkaloids74
Medicinal and mechanistic overview of artemisinin in the treatment of human diseases74
Anti-hepatocellular carcinoma activity of the cyclin-dependent kinase inhibitor AT751974
Unraveling the molecular and immunological landscape: Exploring signaling pathways in osteoporosis74
Physalin pool from Physalis angulata L. leaves and physalin D inhibit P2X7 receptor function in vitro and acute lung injury in vivo74
Sephin1 enhances integrated stress response and autophagy to alleviate myocardial ischemia-reperfusion injury in mice74
Ferroptosis: A novel therapeutic target of natural products against doxorubicin-induced cardiotoxicity74
Drug repurposing for neurodegenerative diseases using Zebrafish behavioral profiles73
Multi-omics study reveals associations among neurotransmitter, extracellular vesicle-derived microRNA and psychiatric comorbidities during heroin and methamphetamine withdrawal73
Development of vericiguat: The first soluble guanylate cyclase (sGC) stimulator launched for heart failure with reduced ejection fraction (HFrEF)73
Monitoring of lamotrigine concentrations in mothers, colostrum, and breastfed newborns during the early postpartum period73
Leveraging knowledge of HDLs major protein ApoA1: Structure, function, mutations, and potential therapeutics73
Excess iron intake induced liver injury: The role of gut-liver axis and therapeutic potential73
Advance on combination therapy strategies based on biomedical nanotechnology induced ferroptosis for cancer therapeutics73
The impact of curcumin on migraine: A comprehensive review72
Role of long noncoding RNAs in pathological cardiac remodeling after myocardial infarction: An emerging insight into molecular mechanisms and therapeutic potential72
AG5 is a potent non-steroidal anti-inflammatory and immune regulator that preserves innate immunity71
The FAAH inhibitor URB597 reduces cocaine intake during conditioned punishment and mitigates cocaine seeking during withdrawal71
Oral sodium butyrate supplementation ameliorates paclitaxel-induced behavioral and intestinal dysfunction71
State of CD8+ T cells in progression from nonalcoholic steatohepatitis to hepatocellular carcinoma: From pathogenesis to immunotherapy71
Microbiota-derived short chain fatty acids: Their role and mechanisms in viral infections70
Retraction notice to “Overexpression of macrophage stimulating 1 enhances the anti-tumor effects of IL-24 in esophageal cancer via inhibiting ERK-Mfn2 signaling-dependent mitophagy” [Biomed. Pharmacot70
Tea (Camellia sinensis) ameliorates DSS-induced colitis and liver injury by inhibiting TLR4/NF-κB/NLRP3 inflammasome in mice70
Injectable Gel-PEG hydrogels as promising delivery system for intravitreal PACAP release: Novel therapeutics for unilateral common carotid artery occlusion induced retinal ischemia70
Therapeutic targets of neuroprotection and neurorestoration in ischemic stroke: Applications for natural compounds from medicinal herbs70
Diet-gut microbiota-epigenetics in metabolic diseases: From mechanisms to therapeutics70
Renal intrinsic cells remodeling in diabetic kidney disease and the regulatory effects of SGLT2 Inhibitors70
Withania somnifera (L.) Dunal (Ashwagandha): A comprehensive review on ethnopharmacology, pharmacotherapeutics, biomedicinal and toxicological aspects69
Puerarin: a potential natural neuroprotective agent for neurological disorders69
Onion (Allium cepa L.) peels: A review on bioactive compounds and biomedical activities69
Elucidating cuproptosis in metabolic dysfunction-associated steatotic liver disease69
Mechanical stress abnormalities promote chondrocyte senescence - The pathogenesis of knee osteoarthritis69
Celastrol has beneficial effects on pulmonary hypertension associated with bronchopulmonary dysplasia: Preclinical study outcomes68
Editorial Board68
Modulatory mechanisms of cannabinoids as a window of hope to patients with sleep-related cardiometabolic risk68
Editorial Board68
Ethanolic extract of Pyrrosia lingua (Thunb.) Farw. ameliorates OVX-induced bone loss and RANKL-induced osteoclastogenesis68
A comprehensive review on pharmacological, toxicity, and pharmacokinetic properties of phillygenin: Current landscape and future perspectives68
Effects of sodium-glucose cotransporter 2 (SGLT2) inhibitors, dapagliflozin and canagliflozin, on the musculoskeletal system in an experimental model of diabetes induced by high-fat diet and streptozo68
Diterpene promptly executes a non-canonical autophagic cell death in doxorubicin-resistant lung cancer67
Corrigendum to “Hominis Placenta modulates PTSD-like behaviors in SPSS-induced PTSD mice: Regulating energy metabolism and neuronal activity” [Biomed. Pharmacother. 178 (2024) 117243]67
Polypharmacological profiling across protein target families and cellular pathways using the multiplexed cell-based assay platform safetyProfiler reveals efficacy, potency and side effects of drugs67
Histamine H3 receptor antagonist/nitric oxide donors as novel promising therapeutic hybrid-tools for glaucoma and retinal neuroprotection67
Treatment of neovascular age-related macular degeneration within 48 h from diagnosis improves long-term functional outcome67
Gilteritinib reverses ABCB1-mediated multidrug resistance: Preclinical in vitro and animal investigations66
L-NRB alleviates amyotrophic lateral sclerosis by regulating P11-Htr4 signaling pathway66
Rosuvastatin restores liver tissue-resident NK cell activation in aged mice by improving mitochondrial function65
Editorial Board65
Emerging roles of long noncoding RNAs in enzymes related intracellular metabolic pathways in cancer biology64
The immune activity of selective estrogen receptor modulators is gene and macrophage subtype-specific yet converges on Il1b downregulation64
Methyleugenol alleviates pulmonary vascular remodeling in rats with high-altitude pulmonary hypertension by improving pulmonary smooth muscle cell function64
YAP-regulated type II alveolar epithelial cell differentiation mediated by human umbilical cord-derived mesenchymal stem cells in acute respiratory distress syndrome64
De novo interleukin-10 production primed by Lactobacillus sakei CVL-001 amplifies the immunomodulatory abilities of mesenchymal stem cells to alleviate colitis64
LCN2: Versatile players in breast cancer64
The role of cGAS/STING signaling in ophthalmological diseases64
Shikonin prevents mice from heat stroke-induced death via suppressing a trigger IL-17A on the inflammatory and oxidative pathways64
Advances of M1 macrophages-derived extracellular vesicles in tumor therapy64
The effect of lipid metabolism on cuproptosis-inducing cancer therapy64
Preclinical animal study of electrospun poly (l-lactide-co-caprolactone) and formulated porcine fibrinogen for full-thickness diabetic wound regeneration64
High accumulation of nivolumab in human breast milk: A case report64
Pharmacological inhibition of AIMP2 aggregation attenuates α-synuclein aggregation and toxicity in Parkinson’s disease64
Emerging role of circular RNAs in the pathobiology of lung cancer64
Molecular insights of a CBP/β-catenin-signaling inhibitor on nonalcoholic steatohepatitis-induced liver fibrosis and disorder63
Inhibition of autophagy and RIP1/RIP3/MLKL-mediated necroptosis by edaravone attenuates blood spinal cord barrier disruption following spinal cord injury63
Blockade of dopamine D3 receptor in ventral tegmental area attenuating contextual fear memory63
A novel GRK2 inhibitor alleviates experimental arthritis through restraining Th17 cell differentiation63
Design and synthesis of 3,4-seco-lupane triterpene derivatives to resist myocardial ischemia-reperfusion injury by inhibiting oxidative stress-mediated mitochondrial dysfunction via the PI3K/AKT/HIF-162
Febuxostat alleviate metabolic dysfunction-associated steatohepatitis in rat model via targeting inflammation, cell death, and intestinal barrier dysfunction62
Nardosinone regulates the slc38a2 gene to alleviate Parkinson's symptoms in rats through the GABAergic synaptic and cAMP pathways62
Possible implication of estrogenic compounds on heart disease in menopausal women62
Protective effect of vaginal resveratrol administration on joint tissues in ovariectomized rats: Targeting mTOR and сaspase 361
Manipulating TGF-β signaling to optimize immunotherapy for cervical cancer61
Evaluation of pro-regenerative and anti-inflammatory effects of isolecanoric acid in the muscle: Potential treatment of Duchenne Muscular Dystrophy60
Therapeutic potential of CAR T cell in malignancies: A scoping review60
Musashi inhibitor Ro 08–2750 attenuates triple-negative breast cancer cell proliferation and migration and acts as a novel chemo- and radiosensitizer60
Targeting a mTOR/autophagy axis: a double-edged sword of rapamycin in spontaneous miscarriage60
Activation of renal CSE/H2S pathway by alpha-lipoic acid protects against histological and functional changes in the diabetic kidney60
The role of hepatocyte mitochondrial DNA in liver injury59
Baicalin attenuates angiotensin II-induced blood pressure elevation and modulates MLCK/p-MLC signaling pathway59
Revolutionizing cancer treatment: The power of dendritic cell-based vaccines in immunotherapy59
Advances in precision gene editing for liver fibrosis: From technology to therapeutic applications59
Transplantation of adipose-derived mesenchymal stem cells ameliorates acute hepatic injury caused by nonsteroidal anti-inflammatory drug diclofenac sodium in female rats59
Health promoting benefits of pongamol: An overview59
Hesperidin ameliorates benign prostatic hyperplasia by attenuating cell proliferation, inflammatory response, and epithelial-mesenchymal transition via the TGF-β1/Smad signaling pathway58
Natural products in anti-tuberculosis host-directed therapy58
Systemic cytokines inhibition with Imp7 siRNA nanoparticle ameliorates gut injury in a mouse model of ventilator-induced lung injury58
Biomedicine and pharmacotherapeutic effectiveness of combinatorial atorvastatin and quercetin on diabetic nephropathy: An in vitro study58
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