Biomedicine & Pharmacotherapy

Papers
(The TQCC of Biomedicine & Pharmacotherapy is 18. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)
ArticleCitations
Editorial Board402
Editorial Board355
Retraction notice to “MiR-155–5p promotes oral cancer progression by targeting chromatin remodeling gene ARID2” [Biomed. Pharmacother. 122 (2020) 109696]343
Recent advances on European research in the field of "Biomedicine & Pharmacotherapy"317
Corrigendum to: ’Protective effect of vaginal resveratrol administration on joint tissues in ovariectomized rats: Targeting mTOR and сaspase 3’ [Biomed. Pharmacother. (2023) 115176/165]300
Corrigendum to “CRKL knockdown promotes in vitro proliferation, migration and invasion, in vivo tumor malignancy and lymph node metastasis of murine hepatocarcinoma Hca-P cells” [Biomed. Pharmacother.296
Editorial Board290
Retraction notice to "Helenalin from Centipeda minima ameliorates acute hepatic injury by protecting mitochondria function, activating Nrf2 pathway and inhibiting NF-κB activation" [Biomed. Pharmacoth289
Cortex periplocae modulates the gut microbiota to restrict colitis and colitis-associated colorectal cancer via suppression of pathogenic Th17 cells286
The use of a selective, nontoxic dual-acting peptide for breast cancer patients with brain metastasis286
Dysregulation of miR-411 in cancer: Causative factor for pathogenesis, diagnosis and prognosis270
Disruption of IL-18 signaling via engineered IL-18BP biologics alleviates experimental cholestatic liver disease234
A new IRES-mediated truncated Cx32 isoform inhibits global mRNA translation to suppress glioblastoma231
Synergic effect of bone marrow derived mesenchymal stem cells and differentiated keratinocytes-like cells with a novel cellulose and collagen nanoscaffold on wound healing in rats225
Rejuvenating hepatic tumor microenvironment immunity with a phosphatidylserine-targeting small molecule drug conjugate218
The role of ubiquitin-specific peptidases in glioma progression213
Efficient generation of a CYP3A4-T2A-luciferase knock-in HepaRG subclone and its optimized differentiation206
CXCL12 inhibits hair growth through CXCR4202
Retraction notice to “Piperine alleviates lipopolysaccharide-induced inflammatory injury by down-regulating microRNA-127 in murine chondrogenic ATDC5 cells” [Biomed. Pharmacother. 103 (2018) 947–954]200
Retraction notice to “Alkannin protects human renal proximal tubular epithelial cells from LPS-induced inflammatory injury by regulation of microRNA-210” [Biomed. Pharmacother. 108 (2018) 1679–1685]187
Seroprevalence of SARS-CoV-2-specific antibodies and vaccination-related adverse events in systemic lupus erythematosus and rheumatoid arthritis184
Ethanolic extract of Pyrrosia lingua (Thunb.) Farw. ameliorates OVX-induced bone loss and RANKL-induced osteoclastogenesis175
Egg white protein hydrolysate ameliorated sepsis-induced inflammatory injuries in kidney and liver based on metabolomics analysis173
Expression of concern: MicroRNA-370 protects against myocardial ischemia/reperfusion injury in mice following sevoflurane anesthetic preconditioning through PLIN5- dependent PPAR signaling pathway [Bi169
Expression of concern: MicroRNA-497 promotes proliferation and inhibits apoptosis of cardiomyocytes through the downregulation of Mfn2 in a mouse model of myocardial ischemia-reperfusion injury [Biome165
Expression of concern: miR-539 enhances chemosensitivity to cisplatin in non-small cell lung cancer by targeting DCLK1 [Biomedicine & Pharmacotherapy 106 (2018) 1072–1081]164
Curcumin modulates multiple cell death, matrix metalloproteinase activation and cardiac protein release in susceptible and resistant Plasmodium berghei-infected mice163
Retraction notice to “Effects of Artesunate on chondrocyte proliferation, apoptosis and autophagy through the PI3K/AKT/mTOR signaling pathway in rat models with rheumatoid arthritis” [Biomed. Pharmaco160
Patient-derived tumor models in cancer research: Evaluation of the oncostatic effects of melatonin160
Editorial Board160
Emerging roles of miR-145 in gastrointestinal cancers: A new paradigm157
PBMCs gene expression signature of advanced cirrhosis with high risk for clinically significant portal hypertension in HIV/HCV coinfected patients: A cross-control study156
Electroencephalographic profile of Salvia amarissima Ortega and amarisolide A in the absence and presence of PTZ-induced seizures in mice154
Potential roles of exosomes in the initiation and metastatic progression of lung cancer153
Editorial Board153
Editorial Board152
Endoplasmic reticulum stress in intestinal microecology: A controller of antineoplastic drug-related cardiovascular toxicity152
Retraction notice to “CircPIP5K1A activates KRT80 and PI3K/AKT pathway to promote gastric cancer development through sponging miR-671-5p” [Biomed. Pharmacother. 126 (2020) 109941]151
Preventive nutritional supplementation with furan fatty acid in a DIO mouse model increases muscle mass and reduces metabolic disorders149
Between therapy effect and false-positive result in animal experimentation147
Molecular insight into arrhythmogenic cardiomyopathy caused by DSG2 mutations147
Resveratrol improves hepatic ischemia-reperfusion injury by inhibiting neutrophils via the ERK signaling pathway146
Hyperbranched polymer dots enhance hair follicle regeneration via Wnt/β-catenin activation: A drug-free nanozyme-based approach to hair growth therapy142
Corrigendum to “I-CBP112 declines overexpression of ATP-binding cassette transporters and sensitized drug-resistant MDA-MB-231 and A549 cell lines to chemotherapy drugs” [Biomed. Pharmacother. 168 (20141
Corrigendum to “Hesperidin ameliorates impairment in hippocampal neural stem cells related to apoptosis induced by methotrexate in adult rats” [Biomed. Pharmacother. 166 (2023), 115329]141
Effects of emulsified and non-emulsified palm tocotrienol on bone and joint health in ovariectomised rats with monosodium iodoacetate-induced osteoarthritis140
Corrigendum to “Secretory products of DPSC mitigate inflammatory effects in microglial cells by targeting MAPK pathway” Biomed. Pharmacother. 170(2024) 115971140
Erythropoietin-mediated IL-17 F attenuates sepsis-induced gut microbiota dysbiosis and barrier dysfunction138
Retraction notice to “Overexpression of macrophage stimulating 1 enhances the anti-tumor effects of IL-24 in esophageal cancer via inhibiting ERK-Mfn2 signaling-dependent mitophagy” [Biomed. Pharmacot137
ACT001 inhibits primary central nervous system lymphoma tumor growth by enhancing the anti-tumor effect of T cells137
The anti-fibrotic efficacy of adelmidrol depends on hepatic PPARγ levels136
Lactobacillus Casei-fermented Amomum Xanthioides Mitigates non-alcoholic fatty liver disease in a high-fat diet mice model135
Drug repurposing for neurodegenerative diseases using Zebrafish behavioral profiles135
Therapeutic strategies targeting synovial cells to treat osteoarthritis135
Glioblastoma targeting by water-soluble hypericin derivate HHL-PVP and photodynamic tumour killing135
Glycogen synthase kinase-3: A potential immunotherapeutic target in tumor microenvironment133
Beneficial effects of carvedilol modulating potassium channels on the control of glucose133
Unraveling the molecular and immunological landscape: Exploring signaling pathways in osteoporosis132
Advance on combination therapy strategies based on biomedical nanotechnology induced ferroptosis for cancer therapeutics130
Oxaliplatin reversibly and differentially affects electrogenic activity of small IB4(+) of male and female rat sensory neurons129
Therapeutic effects of CGS21680, a selective A2A receptor agonist, via BDNF-related pathways in R106W mutation Rett syndrome model128
The significance of dysregulated serine metabolism in depression126
The role of the serotonergic system in atropine’s anti-myopic effects124
Discovery of a novel NUAK1 inhibitor against pancreatic cancer124
Kefir peptides mitigate L-NAME-induced preeclampsia in rats through modulating hypertension and endothelial dysfunction123
Discovery of a synthetic taiwaniaquinoid with potent in vitro and in vivo antitumor activity against breast cancer cells121
Soluble guanylate cyclase stimulation improves cardiac function and mitochondrial activity in a rat model of early-stage heart failure with preserved ejection fraction121
Sesquiterpene lactones as potential therapeutic agents against Naegleria fowleri118
Phytochemicals targeting mitophagy: Therapeutic opportunities and prospects for treating Alzheimer’s disease118
Urolithin A conjugation with NSAIDs inhibits its glucuronidation and maintains improvement of Caco-2 monolayers' barrier function118
Neural crest-derived cells possess differentiation potential to keratinocytes in the process of wound healing117
Carminic acid mitigates fructose-triggered hepatic steatosis by inhibition of oxidative stress and inflammatory reaction117
FM19G11-loaded nanoparticles modulate energetic status and production of reactive oxygen species in myoblasts from ALS mice117
Drug repositioning: Identification of potent inhibitors of NS3 protease and NS5 RdRp for control of DENV infection114
The interaction between ETS transcription factor family members and microRNAs: A novel approach to cancer therapy114
919 granules improve postpartum depression through the regulation of abnormal peripheral blood IL-1β114
Hydroxyurea protects against diabetic cardiomyopathy by inhibiting inflammation and apoptosis114
Anti-inflammatory and inflammasome-modulating effects of Jinmu-Tang, a Korean traditional medicine: Integrated network pharmacology and experimental evaluation in a DSS-induced colitis model113
Normobaric oxygen treatment in a depression-like model in male and female rats – Safety, behavioral benefits, and modulation of serotonin and inflammatory markers113
The three dicaffeoylquinic acids of Erigeron breviscapus strengthen anticoagulation of warfarin in rats: Implications in pharmacokinetics and pharmacodynamics112
Sphingolipid metabolism and insulin resistance – Does cannabigerol protect against experimental colitis induced by high-fat high-sucrose diet?112
Bridging predictions with experimental reality: In vitro evaluation of phenolic natural products as SARS-CoV-2 exoribonuclease inhibitors112
Self-delivery nanodrug to manipulate tumor microenvironment for boosting photodynamic cancer immunotherapy111
In silico and pharmacological study of N,S-acetal juglone derivatives as inhibitors of the P2X7 receptor-promoted in vitro and in vivo inflammatory response110
A comprehensive review on pharmacological, toxicity, and pharmacokinetic properties of phillygenin: Current landscape and future perspectives110
Notoginsenoside Ft1 induces lysosomal cell death and apoptosis by inhibiting the PI3K/AKT/mTOR pathway in hepatocellular carcinoma108
Protective effect of esculentoside A against myocardial infarction via targeting C-X-C motif chemokine receptor 2108
The melatonergic agonist agomelatine ameliorates high fat diet-induced obesity in mice through the modulation of the gut microbiome108
Optimizing mesenchymal stromal cells priming strategies for tailored effects on the secretome108
Colchicine: Emerging therapeutic effects on atrial fibrillation by alleviating myocardial fibrosis in a rat model107
Sephin1 enhances integrated stress response and autophagy to alleviate myocardial ischemia-reperfusion injury in mice107
“Aducanumab” making a comeback in Alzheimer’s disease: An old wine in a new bottle107
Effective-component compatibility of Bufei Yishen formula alleviates chronic obstructive pulmonary disease inflammation by regulating GSK3β-mediated NLRP3 inflammasome activation106
In situ administration of temperature-sensitive hydrogel composite loading paclitaxel microspheres and cisplatin for the treatment of melanoma105
Artesunate promoted anti-tumor immunity and overcame EGFR-TKI resistance in non-small-cell lung cancer by enhancing oncogenic TAZ degradation104
Ferroptosis: A novel therapeutic target of natural products against doxorubicin-induced cardiotoxicity104
Salvadora persica attenuates DMBA-induced mammary cancer through downregulation oxidative stress, estrogen receptor expression and proliferation and augmenting apoptosis104
Basic research on curcumin in cervical cancer: Progress and perspectives103
Induction of JAK2/STAT3 pathway contributes to protective effects of different therapeutics against myocardial ischemia/reperfusion102
Monitoring of lamotrigine concentrations in mothers, colostrum, and breastfed newborns during the early postpartum period101
Whole-exome sequencing reveals genetic variations in humans with differential sensitivity to sevoflurane:A prospective observational study100
State of CD8+ T cells in progression from nonalcoholic steatohepatitis to hepatocellular carcinoma: From pathogenesis to immunotherapy98
Impact of tumor suppressor genes inactivation on the multidrug resistance phenotype of hepatocellular carcinoma cells98
Physiological and transcriptional profiling of surfactin exerted antifungal effect against Candida albicans97
Multi-organ model assessment of neurotoxicity following exposure of liver spheroids to drugs97
Multi-omics study reveals associations among neurotransmitter, extracellular vesicle-derived microRNA and psychiatric comorbidities during heroin and methamphetamine withdrawal97
Oral administration of Bifidobacterium longum and Bifidobacterium infantis ameliorates cefcapene pivoxil-induced attenuation of anti-programmed cell death protein-1 antibody action in mice96
Bacterial outer membrane vesicles in cancer: Biogenesis, pathogenesis, and clinical application96
Celastrol exerts antiarrhythmic effects in chronic heart failure via NLRP3/Caspase-1/IL-1β signaling pathway96
Unveiling the role of ferroptosis-associated exosomal non-coding RNAs in cancer pathogenesis96
CircRNA: An emerging star in the progression of glioma96
Renal intrinsic cells remodeling in diabetic kidney disease and the regulatory effects of SGLT2 Inhibitors96
Scutellarin enhances anti-tumor immune responses by reducing TNFR2-expressing CD4+Foxp3+ regulatory T cells95
Cinnarizine dissolving microneedles against microwave-induced brain injury95
Combination of rosuvastatin and curcumin outperforms monotherapies in alleviating gentamicin-induced nephrotoxicity, audiotoxicity and vestibulotoxicity in a rat animal model94
Silencing tumor-intrinsic CD73 enhances the chemosensitivity of NSCLC and potentiates the anti-tumoral effects of cisplatin: An in vitro study94
Phenolic zingerone nanoparticles impede cell cycle progression to compete against human urothelial carcinoma94
A phytotherapic blend immunity-6™ inhibits myeloid leukemic cells 2 activation involving purinergic signaling94
Non-coding RNAs in metabolic reprogramming of bone and soft tissue sarcoma: Fundamental mechanism and clinical implication93
Areca catechu L. ameliorates chronic unpredictable mild stress-induced depression behavior in rats by the promotion of the BDNF signaling pathway93
AG5 is a potent non-steroidal anti-inflammatory and immune regulator that preserves innate immunity93
Amifostine loaded lipid-calcium carbonate nanoparticles as an oral drug delivery system for radiation protection91
Zhen-Wu-Tang ameliorates lupus nephritis by diminishing renal tissue-resident memory CD8+ T cells via suppressing IL-15/STAT3 pathway91
Overcoming drug delivery barriers and challenges in topical therapy of atopic dermatitis: A nanotechnological perspective91
Caffeic acid phenethyl ester inhibits MDA-MB-231 cell proliferation in inflammatory microenvironment by suppressing glycolysis and lipid metabolism91
RETRACTED: mPEG-b-P(Glu-co-Phe) nanoparticles increase gastric retention time and gastric ulcer treatment efficacy of 20(S)-ginsenoside Rg390
Effects of cPIP2 peptide and rosuvastatin on TLR4 signaling and cardiac remodeling in an acute myocardial infarction model90
Granulocyte colony-stimulating factor in reproductive-related disease: Function, regulation and therapeutic effect90
Leveraging knowledge of HDLs major protein ApoA1: Structure, function, mutations, and potential therapeutics90
NADPH and NAC synergistically inhibits chronic ocular hypertension-induced neurodegeneration and neuroinflammation through regulating p38/MAPK pathway and peroxidation90
Empagliflozin adjunct with metformin for the inhibition of hepatocellular carcinoma progression: Emerging approach for new application90
Breaking the vicious cycle: Targeting the NLRP3 inflammasome for treating sepsis-associated encephalopathy89
The prospect of combination therapies with the third-generation EGFR-TKIs to overcome the resistance in NSCLC89
The AhR/P38 MAPK pathway mediates kynurenine-induced cardiomyocyte damage: The dual role of resveratrol in apoptosis and autophagy89
Targeting hypoxia-related metabolism molecules: How to improve tumour immune and clinical treatment?89
Supplementation of conventional anti-diabetic therapy with alpha-lipoic acid prevents early development and progression of diabetic nephropathy89
Mechanical stress abnormalities promote chondrocyte senescence - The pathogenesis of knee osteoarthritis89
Role of SARS-COV-2 and ACE2 in the pathophysiology of peripheral vascular diseases88
Tea (Camellia sinensis) ameliorates DSS-induced colitis and liver injury by inhibiting TLR4/NF-κB/NLRP3 inflammasome in mice88
The impact of curcumin on migraine: A comprehensive review88
Development of vericiguat: The first soluble guanylate cyclase (sGC) stimulator launched for heart failure with reduced ejection fraction (HFrEF)88
Clofazimine: A journey of a drug87
Corrigendum to “Areca catechu L. ameliorates chronic unpredictable mild stress-induced depression behavior in rats by the promotion of the BDNF signaling pathway” [Biomed. Pharmacother. 164 (2023), 1187
Cytosolic DNA sensing pathway in senescence and aging: Underlying mechanisms and targeted interventions86
Relationship between hepatic lipid accumulation and type 2 diabetes mellitus86
Corrigendum to “Bicyclol ameliorates nonalcoholic fatty liver disease in mice via inhibiting MAPKs and NF-κB signaling pathways” [Biomed. Pharmacother. 141 (2021) 1–12/111874]86
Corrigendum to “High potency of magnetic iron oxide nanoparticles covered by piroctone olamine against cystic echinococcosis” [Biomed. Pharmacother., 2023 (161) 114536]86
Cannabidiol promotes fine-tuning of natural killer and monocytic cells subsets as well as cytokine storm during chikungunya virus exposure in vitro: Insights for putative therapeutic interventions86
Identification of early diagnostic biomarkers via WGCNA in gastric cancer85
The FAAH inhibitor URB597 reduces cocaine intake during conditioned punishment and mitigates cocaine seeking during withdrawal85
Role of epigenetics in the regulation of skin aging and geroprotective intervention: A new sight84
Antiseizure effects of Lilii Bulbus on pentylenetetrazol kindling-induced seizures in mice: Involvement of Reelin, Netrin-1, and semaphorin84
Si-Ni-San reverses dietary fat absorption defects in a murine model of depression84
A combined transcriptomics and proteomics approach to reveal the mechanism of AEE relieving hyperlipidemia in ApoE-/- mice84
T helper 17 (Th17) cell responses to the gut microbiota in human diseases83
Sildenafil delays bone remodeling of fractured femora in aged mice by reducing the number and activity of osteoclasts within the callus tissue83
Microbiota-derived short chain fatty acids: Their role and mechanisms in viral infections83
Medicinal and mechanistic overview of artemisinin in the treatment of human diseases82
Interleukin-6 in SARS-CoV-2 induced disease: Interactions and therapeutic applications82
Onion (Allium cepa L.) peels: A review on bioactive compounds and biomedical activities82
Role of long noncoding RNAs in pathological cardiac remodeling after myocardial infarction: An emerging insight into molecular mechanisms and therapeutic potential81
Venetoclax in adult acute myeloid leukemia80
Palbociclib promotes the antitumor activity of Venetoclax plus Azacitidine against acute myeloid leukemia80
Cuproptosis in cancers: Function and implications from bench to bedside80
Analytical validation of a novel UHPLC-MS/MS method for 19 antibiotics quantification in plasma: Implementation in a LC-MS/MS Kit79
Anti-hepatocellular carcinoma activity of the cyclin-dependent kinase inhibitor AT751979
Injectable Gel-PEG hydrogels as promising delivery system for intravitreal PACAP release: Novel therapeutics for unilateral common carotid artery occlusion induced retinal ischemia78
The phenolic compounds tyrosol and hydroxytyrosol counteract liver fibrogenesis via the transcriptional modulation of NADPH oxidases and oxidative stress-related miRNAs78
Polyphyllin I induces ferritinophagy dependent ferroptosis through EZH2 and promotes anti-tumor immunity78
Experimental and approved treatments for skin photosensitivity in individuals with erythropoietic protoporphyria or X-linked protoporphyria: A systematic review78
Polyphenol-enriched Desmodium elegans DC. ameliorate scopolamine-induced amnesia in animal model of Alzheimer’s disease: In Vitro, In Vivo and In Silico approaches78
Tracking Chlamydia – Host interactions and antichlamydial activity in Caenorhabditis elegans78
Extract of Jasminum grandiflorum L. alleviates CCl4-induced liver injury by decreasing inflammation, oxidative stress and hepatic CYP2E1 expression in mice78
Dihydromyricetin treats pulmonary hypertension by modulating CKLF1/CCR5 axis-induced pulmonary vascular cell pyroptosis77
Necroptosis in Alzheimer’s disease: Potential therapeutic target77
Modulating autophagy to boost the antitumor efficacy of TROP2-directed antibody-drug conjugate in pancreatic cancer77
Excess iron intake induced liver injury: The role of gut-liver axis and therapeutic potential76
Therapeutic targets of neuroprotection and neurorestoration in ischemic stroke: Applications for natural compounds from medicinal herbs76
Elucidating cuproptosis in metabolic dysfunction-associated steatotic liver disease76
Streptococcus thermophilus CNCM I-5570 lysate counteracts the aging process in human dermal fibroblast cells by neutralizing harmful free radicals and impacting antioxidant and anti-inflammatory pathw76
Targeting the STAT3 oncogenic pathway: Cancer immunotherapy and drug repurposing76
Oral sodium butyrate supplementation ameliorates paclitaxel-induced behavioral and intestinal dysfunction75
Imbalance of gut microbiota is involved in the development of chronic obstructive pulmonary disease: A review75
Toll-like receptor 4: A potential therapeutic target for multiple human diseases75
Long non-coding RNAs and exosomal lncRNAs: Potential functions in lung cancer progression, drug resistance and tumor microenvironment remodeling75
Simple ammonium salt and sigma-1 receptor ligand dipentylammonium provides neuroprotective effects in cell culture and Caenorhabditis elegans models of Alzheimer's disease74
Advances in the role and mechanism of miRNA in inflammatory pain74
Development of alginate and alginate sulfate/polycaprolactone nanoparticles for growth factor delivery in wound healing therapy73
Antioxidant effects of Paeoniflorin and relevant molecular mechanisms as related to a variety of diseases: A review73
Targeting mitochondria as a potential therapeutic strategy against chemoresistance in cancer73
The pharmacokinetic property and pharmacological activity of acteoside: A review73
Diet-gut microbiota-epigenetics in metabolic diseases: From mechanisms to therapeutics73
Puerarin: a potential natural neuroprotective agent for neurological disorders73
Intestinal epithelial cell-derived exosomes package microRNA-23a-3p alleviate gut damage after ischemia/reperfusion via targeting MAP4K472
Celastrol has beneficial effects on pulmonary hypertension associated with bronchopulmonary dysplasia: Preclinical study outcomes72
The role of miR-155 in urologic malignancies72
Modulatory mechanisms of cannabinoids as a window of hope to patients with sleep-related cardiometabolic risk72
Investigation of the cardioprotective effects of Momordica charantia in the isoproterenol-induced myocardial infarction model in rats72
Rosuvastatin restores liver tissue-resident NK cell activation in aged mice by improving mitochondrial function71
Examining the pharmacokinetic and pharmacodynamic interaction of N,N-dimethyltryptamine and harmine in healthy volunteers: Α factorial dose-escalation study71
Targeting ROCK1 in diabetic kidney disease: Unraveling mesangial fibrosis mechanisms and introducing myricetin as a novel antagonist71
LCN2: Versatile players in breast cancer71
Shikonin prevents mice from heat stroke-induced death via suppressing a trigger IL-17A on the inflammatory and oxidative pathways70
Xinshubao tablet ameliorates myocardial injury against heart failure via the DCN/PPARα/PGC-1α/P300 pathway70
Non-apoptotic cell death in ovarian cancer: Treatment, resistance and prognosis70
Transplantation of adipose-derived mesenchymal stem cells ameliorates acute hepatic injury caused by nonsteroidal anti-inflammatory drug diclofenac sodium in female rats70
San-Huang-Yi-Shen capsule ameliorates diabetic nephropathy in mice through inhibiting ferroptosis69
Jiangu granule ameliorated OVX rats bone loss by modulating gut microbiota-SCFAs-Treg/Th17 axis69
Hesperidin ameliorates benign prostatic hyperplasia by attenuating cell proliferation, inflammatory response, and epithelial-mesenchymal transition via the TGF-β1/Smad signaling pathway69
Comparative evaluation of doxorubicin, cyclophosphamide, 5-fluorouracil, and cisplatin on cognitive dysfunction in rats: Delineating the role of inflammation of hippocampal neurons and hypothyroidism68
Safety assessment of the SGLT2 inhibitors empagliflozin, dapagliflozin and canagliflozin during pregnancy: An ex vivo human placenta perfusion and in vitro study68
Anti-photoaging effect and mechanism of flexible liposomes co-loaded with apigenin and doxycycline68
Nardosinone regulates the slc38a2 gene to alleviate Parkinson's symptoms in rats through the GABAergic synaptic and cAMP pathways68
Rosemary extract activates oligodendrogenesis genes in mouse brain and improves learning and memory ability68
Nano-vitamin C: A promising candidate for therapeutic applications68
Targeting a mTOR/autophagy axis: a double-edged sword of rapamycin in spontaneous miscarriage67
Exploring the therapeutic potential of regulatory T cell in rheumatoid arthritis: Insights into subsets, markers, and signaling pathways67
Enhancing the biopharmaceutical attributes of atorvastatin calcium using polymeric and lipid-polymer hybrid nanoparticles: An approach for atherosclerosis treatment67
Dipeptidyl peptidase-4 inhibitor linagliptin reduces inflammatory response, ameliorates tissue edema formation, and improves survival in severe sepsis67
Biomedicine and pharmacotherapeutic effectiveness of combinatorial atorvastatin and quercetin on diabetic nephropathy: An in vitro study67
Pinocembrin's protective effect against acute pancreatitis in a rat model: The correlation between TLR4/NF-κB/NLRP3 and miR-34a-5p/SIRT1/Nrf2/HO-1 pathways67
COVID-19 and diabetes: Association intensify risk factors for morbidity and mortality67
Angiotensin-converting enzyme inhibitors and statins therapies-induced changes in omics profiles in humans and transgenic tau mice66
Recombinant canstatin inhibits the progression of hepatocellular carcinoma by repressing the HIF-1α/VEGF signaling pathway66
Targeted mitigation of neointimal hyperplasia via magnetic field-directed localization of superparamagnetic iron oxide nanoparticle-labeled endothelial progenitor cells following carotid balloon cathe65
The role of cGAS/STING signaling in ophthalmological diseases65
Triciribine attenuates pathological neovascularization and vascular permeability in a mouse model of proliferative retinopathy65
Bromophenanthrenequinones as antimicrobial and antibiofilm agents against Staphylococcus aureus65
Pharmacokinetics and clinical efficacy of 6′-sialyllactose in patients with GNE myopathy: Randomized pilot trial65
1,8-cineole ameliorates experimental diabetic angiopathy by inhibiting NLRP3 inflammasome-mediated pyroptosis in HUVECs via SIRT265
Ootheca mantidis mitigates renal fibrosis in mice by the suppression of apoptosis via increasing the gut microbe Akkermansia muciniphila and modulating glutamine metabolism65
PLK1 regulating chemoradiotherapy sensitivity of esophageal squamous cell carcinoma through pentose phosphate pathway/ferroptosis64
The role of metabolic reprogramming in cancer metastasis and potential mechanism of traditional Chinese medicine intervention64
Multifaceted entrancing role of glucose and its analogue, 2-deoxy-D-glucose in cancer cell proliferation, inflammation, and virus infection64
A novel GRK2 inhibitor alleviates experimental arthritis through restraining Th17 cell differentiation64
Riboceine and N-acetylcysteine protect normal prostate cells from chemotherapy-induced oxidative stress while selectively modulating the cytotoxicity of methotrexate and docetaxel in prostate (PC-3) a64
Protective effect of vaginal resveratrol administration on joint tissues in ovariectomized rats: Targeting mTOR and сaspase 363
Emerging roles of long noncoding RNAs in enzymes related intracellular metabolic pathways in cancer biology63
Blockade of dopamine D3 receptor in ventral tegmental area attenuating contextual fear memory62
Gilteritinib reverses ABCB1-mediated multidrug resistance: Preclinical in vitro and animal investigations62
Polypharmacological profiling across protein target families and cellular pathways using the multiplexed cell-based assay platform safetyProfiler reveals efficacy, potency and side effects of drugs62
Musashi inhibitor Ro 08–2750 attenuates triple-negative breast cancer cell proliferation and migration and acts as a novel chemo- and radiosensitizer62
Systemic cytokines inhibition with Imp7 siRNA nanoparticle ameliorates gut injury in a mouse model of ventilator-induced lung injury62
L-NRB alleviates amyotrophic lateral sclerosis by regulating P11-Htr4 signaling pathway62
VU0810464, a selective GIRK channel activator, improves hippocampal-dependent synaptic plasticity and memory disrupted by amyloid-β oligomers62
Editorial Board62
Corrigendum to “Hominis Placenta modulates PTSD-like behaviors in SPSS-induced PTSD mice: Regulating energy metabolism and neuronal activity” [Biomed. Pharmacother. 178 (2024) 117243]62
Febuxostat alleviate metabolic dysfunction-associated steatohepatitis in rat model via targeting inflammation, cell death, and intestinal barrier dysfunction61
Do immune checkpoint inhibitors share the same pharmacological feature in the risk of cardiac arrhythmias?61
Inhibition of autophagy and RIP1/RIP3/MLKL-mediated necroptosis by edaravone attenuates blood spinal cord barrier disruption following spinal cord injury61
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