Fundamental & Clinical Pharmacology

Article	Citations
In vitro evidence that the vasorelaxant effects of 2‐nitro‐1‐phenyl‐1‐propanol on rat coronary arteries involve cyclic nucleotide pathways	52
Diarrhea and angiotensin II receptor blockers: Is there any difference between the different drugs?	52
Can cannabidiol have an analgesic effect?	51
Alamandin and especially melatonin attenuate pulmonary arterial hypertension induced by monocrotalin	48
Protective Effects of Cannabis sativa on chemotherapy‐induced nausea in a rat: Involvement of CB1 receptors	37
Location matters: Overlooked ethnic‐geographic effect in China and Austria on propofol/cisatracurium sex differences among a population pharmacokinetic/pharmacodynamic (PopPK/PD) covariate analysis in	31
Inhibition of NorA efflux pump of Staphylococcus aureus by anacardic acids isolated from the cashew nutshell liquid of Anacardium occidentale L.	28
Effect of ceftriaxone on intestinal transit time	27
Efficacy of COVID‐19 vaccines: Several modes of expression should be presented in scientific publications	27
Effects of clarithromycin on the pharmacokinetics of tacrolimus and expression of CYP3A4 and P‐glycoprotein in rats	23
Calcium dobesilate protects against d‐galactose‐induced hepatic and renal dysfunction, oxidative stress, and pathological damage	20
MiR‐199a‐3p in mouse bone marrow mesenchymal stem cell exosomes increases epithelial sodium channel expression in lung injury	17
Roflumilast improves resolution of sepsis‐induced acute kidney injury by retarding late phase renal interstitial immune cells infiltration and leakage in urinary sediments	17
Improvement of cognitive dysfunction by a novel phosphodiesterase type 5 inhibitor, Tadalafil	17
Methylsulfonylmethane induces caspase‐dependent apoptosis in acute myeloid leukemia cell lines	17
Novel ginsenoside monomer RT4 promotes colitis repair in mice by regulating miR‐144‐3p/SLC7A11 signaling pathway	17
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In vitro inhibition and molecular docking of a new ciprofloxacin‐chalcone against SARS‐CoV‐2 main protease	16
Tofacitinib improved peripheral endothelial dysfunction and brain‐derived neurotrophic factor levels in the rat adjuvant‐induced arthritis model	15
The protective effect of α7‐nACh receptor and its interaction with 5‐HT1B/1D receptors in acute intestinal ischemia‐reperfusion injury in rats	15
Relative bioavailability and pharmacokinetic comparison of a fixed‐dose combination tablet of mosapride, pancreatin, and simethicone relative to single‐component mosapride tablets in healthy Mexican s	14
Sakuranetin exerts anticonvulsant effect in bicuculline‐induced seizures	14
Cell therapy procedure using anti‐inflammatory macrophage M2 can potentially reduce Clinical Score in animals with Experimental Autoimmune Encephalomyelitis: A preclinical systematic review and meta‐a	13
Precipitation of sugammadex with nicardipine and labetalol: A laboratory research	12
Repurposing of atorvastatin and metformin denotes their individual and combined antiproliferative effects in non‐small cell lung cancer	12

Treatment implications of augmented renal clearance in a critically ill COVID‐19 patient: A case report	12
Evaluation of anti‐inflammatory activity of kaurenol: Experimental evaluation and mechanistic insights	12
Gemfibrozil, a lipid‐lowering drug, improves hepatorenal damages in a mouse model of aging	12
Metformin improves neurobehavioral impairments of streptozotocin‐treated and western diet‐fed mice: Beyond glucose‐lowering effects	12
Cover Image, Volume 36, Issue 1	11
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Targeting autophagy with tamoxifen in breast cancer: From molecular mechanisms to targeted therapy	11
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Master 2 Award	11
Spontaneous reporting of adverse drug reactions as an outlet for patient dismay? The case of Levothyrox® change of excipients	10
Vestibular disorders following BNT162b2 mRNA COVID‐19 vaccination: A retrospective case series	10
UPLC‐MS analysis and network pharmacology‐based investigation into the active ingredients and molecular mechanisms of anti‐fatigue of male flowers with Eucommia ulmoides Oliv.	10
Population pharmacokinetics of mycophenolate in patients treated for interstitial lung disease (EVER‐ILD study)	10
Histamine H1‐ and H2‐receptors participate to provide metabolic energy differently	10
Acetazolamide suppresses the progression of hepatocellular carcinoma induced by diethylnitrosamine in Wistar albino rats	10
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Sitagliptin's renoprotective effect in a diabetic nephropathy model in rats: The potential role of PI3K/AKT pathway	9
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Oxidative stress and mitochondrial dysfunction following traumatic brain injury: From mechanistic view to targeted therapeutic opportunities	9
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Discussed Poster Abstracts	9
Chlorogenic acid co‐administration alleviates cisplatin‐induced peripheral neuropathy in rats	9
Capivasertib augments chemotherapy via Akt inhibition in preclinical small cell lung cancer models	8
Therapeutic targeting of DNA damage repair pathways guided by homologous recombination deficiency scoring in ovarian cancers	8
Vitamin D lacks efficacy: A re‐analysis of a systematic review using the REB method	8
Use of real‐world evidence in translational pharmacology research	8
A novel naphthylchalcone ([E]‐4‐(3‐[naphthalen‐2‐yl]‐3‐oxoprop‐1‐en‐1‐yl) induces intrinsic and extrinsic apoptosis in human acute leukemia cell lines	8
Differential expression and activities of cytochrome P450 3A in the rat brain microsomes and mitochondria	8
Chemsex practice in France: An update in Addictovigilance data	8
The protective effect of 3‐indolepropanoic acid on aflatoxin B1‐induced systemic perturbation of the liver and kidney function in rats	8
A comprehensive view on the quercetin impact on bladder cancer: Focusing on oxidative stress, cellular, and molecular mechanisms	8
Inhibition of plasminogen suppresses fibrosis and macrophage foaming in a nonalcoholic steatohepatitis mouse model	8
Necrostatin‐1 attenuates oral squamous cell carcinoma by modulating tumour immune response in mice	8
Anti‐oxidative and anti‐neuroinflammatory role of Necrostatin‐1s and docosahexaenoic acid in RIP‐1‐mediated neurotoxicity in MPTP‐induced Parkinson's disease model	7
Advances in the phytochemical screening and biological potential of propolis	7
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Benzimidazole derivatives: A versatile scaffold for drug development against Helicobacter pylori‐related diseases	7
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Inhibition of kidney potassium channels by fluoxetine: In vivo and in vitro studies	7
Bupivacaine inhibits the TLR4‐ and TLR2‐Myd88/NF‐κB pathways in human leukocytes	7
Discussed Poster Abstracts – PM2	7
Effect of a high‐fat meal on the relative bioavailability of HMPL‐689 in Chinese healthy volunteers	7
Prospective pilot study evaluating a vitamin D3 loading dose in critically ill children with vitamin D deficiency	7
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Animal models for the evaluation of antipsychotic agents	7
Effects of nalbuphine on the cardiotoxicity of ropivacaine in rats	7
Adrenaline enhances nociceptive and motor blockades by intrathecal carteolol and oxprenolol in rats	7
Antihypertensive and lipid‐lowering drugs usage after primary stroke in a large representative sample of the French population	7
Association between immune‐related adverse events and prognosis in patients treated with immune checkpoint inhibitors in melanoma: A surrogacy analysis	7

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Vitamin D3 potentiates the nephroprotective effects of vildagliptin–metformin combination in a rat model of metabolic syndrome	7
The effects of cannabidiol on subjective states, cognition, and psychomotor function in healthy adults: A randomized clinical trial	6
Deliberation on debilitating condition of cancer cachexia: Skeletal muscle wasting	6
Drug news and therapeutic news	6
Atorvastatin ameliorates α‐KGDH and GDH functions in rats with diet‐induced hypercholesterolemia	6
The vascular impact of dapagliflozin, liraglutide, and atorvastatin alone or in combinations in type 2 diabetic rat model	6
Recognition of potential therapeutic role of 2‐hydroxy‐3‐methylanthraquinones in the treatment of gallbladder carcinoma: A proteomics analysis	6
A systematic strategy for investigating the pharmacological effects and mechanism of traditional Chinese medicinal formula: Guilin Xiguashuang as a case	6
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Drug‐induced radiation recall reactions and non‐anticancer drugs: A descriptive analysis from VigiBase®	6
Discussed Poster Abstracts – PM1	6
Prevalence of medication administration errors in hospitalized adults: A systematic review and meta‐analysis up to 2017 to explore sources of heterogeneity	6
Update on monkeypox virus infection: Focusing current treatment and prevention approaches	6
Involvement of different K+ channel subtypes in hydrogen sulfide‐induced vasorelaxation of human internal mammary artery	6
Lacosamide use during breastfeeding: A case report and a literature review	6
Master 2 award	6
Chronic polypharmacy at all age: A population‐based drug utilization study	6
Population pharmacokinetics of sivelestat in Chinese patients with severe pneumonia	5
Is lithium neuroprotective? An updated mechanistic illustrated review	5
Afatinib triggers a Ni2+‐resistant Ca2+ influx pathway in A549 non‐small cell lung cancer cells	5
Knockdown of RFC3 enhances the sensitivity of colon cancer cells to oxaliplatin by inducing ferroptosis	5
Pharmacokinetic and pharmacodynamic study of three products of epoetin alfa as single subcutaneous dose in healthy volunteers	5
JAK/STAT inhibitors mitigate sepsis‐associated cerebral and cognitive injury	5
Oral Communication Abstracts	5
Inflammatory molecules facilitate the development of docetaxel‐resistant prostate cancer cells in vitro and in vivo	5
Thesis awards	5
Immunomodulatory effect of IL‐35 gene‐transfected mesenchymal stem cells on allergic asthma	5
Development of a Bayesian estimation tool to determine the optimal duration of apixaban discontinuation before a high‐bleeding risk procedure	5
Second primary cancers and hormonal therapies for prostate cancer: A nested case–control study	5
Potentiation of antibiotic activity, and efflux pumps inhibition by (2E)‐1‐(4‐aminophenyl)‐3‐(4‐fluorophenyl)prop‐2‐en‐1‐one	5
LQM10, a guanylhydrazone derivative, reduces nociceptive and inflammatory responses in mice	5
Potentiating‐antibiotic activity and absorption, distribution, metabolism, excretion and toxicity properties (ADMET) analysis of synthetic thiadiazines against multi‐drug resistant (MDR) strains	5
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Immunomodulator FTY720 improves glucose homeostasis and diabetic complications by rejuvenation of β‐cell function in nonhuman primate model of diabetes	5
ADMET study, spectroscopic characterization and effect of synthetic nitro chalcone in combination with norfloxacin, ciprofloxacin, and ethidium bromide against Staphylococcus aureus	5
Angiotensin receptor–neprilysin inhibitor (thiorphan/irbesartan) improved cardiac function in a rat model of myocardial ischemic reperfusion injury	5
A mini‐review on anticancer‐related properties of azithromycin and its potential activities in overcoming the challenges of glioblastoma	5
In vitro evidence that the anti‐inflammatory effect of synthetic cinnamate‐derived dienes is directly linked to a macrophage repolarization	5
Probing polypharmacy, ageing and sex effects on physical function using different tests	5
Borolatonin limits cognitive deficit and neuron loss while increasing proBDNF in ovariectomised rats	5
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Analgesic switching in chronic users of dextropropoxyphene in France	5
Mechanism research on microRNA‐669f‐5p/deoxycytidylate deaminase axis mediating sevoflurane‐induced cognitive dysfunction in aged mice	4
Pharmacological treatment for mental health illnesses in adults receiving dialysis: A scoping review	4
Antinociceptive, anxiolytic, and depression‐like effects of hydrogen sulfide, nitric oxide, and carbon monoxide in rats and the role of opioidergic and serotonergic systems in antinociceptive activity	4
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Fundamental and Clinical Pharmacology of drug repositioning	4
KATP channels are regulators of programmed cell death and targets for the creation of novel drugs against ischemia/reperfusion cardiac injury	4
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Antimanic‐like effect of dipyridamole in the methylphenidate‐induced hyperlocomotion	4
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Insights into nanostructured lipid carriers of etoricoxib for mitigating radiation‐induced lung inflammation and exploring anti‐inflammatory mechanisms in rats	4
Edaravone dexborneol protects cerebral ischemia reperfusion injury through activating Nrf2/HO‐1 signaling pathway in mice	4
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Study of prescription‐indication of tetracyclines in a population in Colombia	4
(−)‐Epicatechin improves body composition of male rats descendant of obese mothers postnatally fed with a high‐fat diet	4
Prognostic roles of dysregulated METTL3 protein expression in cancers and potential anticancer value by inhibiting METTL3 function	4
Interaction of buspirone and its major metabolites with human organic cation transporters	4
Trends in adverse drug reactions related to oral weak opioid analgesics in therapeutic use in adults: A 10‐year French vigilances retrospective study	4
Buprenorphine exposures in adolescents and adults: A 10‐year experience of a French Poison Control Center	4
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Vortioxetine improved schizophrenia‐like behavioral deficits in a Poly I:C‐induced maternal immune activation model of schizophrenia in rats	4
Busulfan induces steatosis in HepaRG cells but not in primary human hepatocytes: Possible explanations and implication for the prediction of drug‐induced liver injury	4
Combination of human papillomaviruses L1 and L2 multiepitope constructs protects mice against tumor cells	4
The role of β‐adrenergic receptors in the regulation of cardiac tolerance to ischemia/reperfusion. Why do β‐adrenergic receptor agonists and antagonists protect the heart?	4
Pro‐inflammatory cytokines mediating senescence of vascular endothelial cells in atherosclerosis	4
Patch testing versus interferon‐gamma release assay in evaluation of drug eruptions	4
Latest advances in the reversal strategies for direct oral anticoagulants	4
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Intradermal testing of iodinated contrast media: Should we test up to pure or with diluted compounds only?	3
Pre‐treatment or post‐treatment with hydroxychloroquine demonstrates neuroprotective effects in cerebral ischemia/reperfusion	3
Evaluation of potential antiviral activities of antimicrobial peptides in fish mucus	3
Effects of 27 CYP3A4 protein variants on saxagliptin metabolism in vitro	3
Author Index	3
Efficacy and safety of topiramate for reducing impulsivity: A transdiagnostic systematic review and meta‐analysis of a common clinical use	3
Physiologically Based Pharmacokinetic modelling of drugs in pregnancy: A mini‐review on availability and limitations	3
Author index	3

Pentosan polysulfate exerts anti‐inflammatory effect and halts albuminuria progression in diabetic nephropathy: Role of combined losartan	3
Theme and main topic index	3
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Bezafibrate mitigates oxidized‐low density lipoprotein (ox‐LDL)‐induced the attachment of monocytes to endothelial cells: An implication in atherosclerosis	3
Standardized study of atorvastatin possible osteoarthritis disease‐modifying effect in a rat model of osteoarthritis	3
Role of biomarkers and molecular signaling pathways in acute lung injury	3
Immunomodulatory effect of N‐acetyl‐seryl‐aspartyl‐proline and vasoactive intestinal peptide on chronic obstructive pulmonary disease pathophysiology	3
Sodium hypochlorite accident diagnosis and management: Analysis from the literature and the French pharmacovigilance database	3
Discussed Poster Abstracts	3
Telmisartan: An angiotensin receptor blocker regulates osteoclastogenesis via inhibition of the ERK triggering in osteoporotic male rats	3
Alterations in the gene expression of SARS‐COV‐2 entry receptors and enzymes in lungs and hearts of controlled and uncontrolled diabetic mice	3
Hesperidin improves physiological outcomes in an arginine vasopressin rat model of pre‐eclampsia	3
Photobiological effect of eugenol‐derived 3‐benzoylcoumarin associated with led lights against MDR microorganisms	3
Advances on pharmacology and toxicology of aconitine	3
Thesis Awards	3
FKA‐A NPs enhances PTX‐A NPs efficacy to suppress ovarian cancer via regulating Skp2/YAP pathway	3
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Investigating the link between drug consumption and adverse events reporting in France	3
Exploring the therapeutic potential of Modafinil in mitigating renal ischemia–reperfusion injury in rats	3
Molecular mechanisms of Alzheimer's disease: From therapeutic targets to promising drugs	3
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The protective effect of pregabalin and xanthenone on testicular ischemia/reperfusion injury in rats	3
Heterogeneity in protocols and outcomes to study the effect of renin‐angiotensin system blockers in inflammatory bowel disease: A systematic review	3
Glibenclamide promoted functional recovery following sciatic nerve injury in male Wistar rats	3
Effects of the nerve growth factor and its carrier protein on the inflammatory response from human monocytes	3
Sodium‐glucose cotransporter‐2 inhibitor (SGLT2i) plus glucagon‐like peptide type 1 receptor combination is more effective than SGLT2i plus dipeptidyl peptidase‐4 inhibitor combination in treating obe	3
Issue Information	3
The state of astragaloside IV research: A bibliometric and visualized analysis	2
Chemsex in HIV pre‐exposure prophylaxis users: Assessment of mood disorders and addictive behavior	2
Repurposing bosentan as an anticancer agent: EGFR/ERK/c‐Jun modulation inhibits NSCLC tumor growth	2
Dual ETA‐ETB receptor antagonism improves metabolic syndrome‐induced heart failure with preserved ejection fraction	2
The synergy between alkylating agents and ERCC1–XPF inhibitors is p53 dependent	2
Effect of spermidine on long non‐coding RNAs MALAT1 in a rotenone induced‐rat model of Parkinson's disease	2
Inhibitory effects and molecular mechanisms of ginsenoside Rg1 on the senescence of hematopoietic stem cells	2
Isobolographic analysis of the ciprofloxacin–gentamicin combination against beta‐lactamase‐producing Staphylococcus aureus	2
Role of angiotensin receptor blockers in the context of Alzheimer's disease	2
Effect of food intake on the pharmacokinetics of rivoceranib in healthy subjects	2
Breastfeeding and contrast agents—A critical review and presentation of new aspects	2
Effects of acute ethanol and/or diazepam exposure on immediate and delayed hippocampal metabolite levels in rats anesthetized with isoflurane	2
Induction of Ca2+ signaling and cytotoxic responses of human lung fibroblasts upon an antihistamine drug oxatomide treatment and evaluating the protective effects of Ca2+ chelati	2
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MNK/eIF4E inhibition overcomes anlotinib resistance in non‐small cell lung cancer	2
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Role of apoptosis and autophagy in folic acid‐induced cytotoxicity of human breast cancer cells in vitro	2
New ways to repurpose salmeterol in an animal model of fibromyalgia	2
Metformin counters oxidative stress and mitigates adverse effects of radiation exposure: An overview	2
Hypoglycemic effect on adult zebrafish (Danio rerio) of the 3β‐6β‐16β‐trihydroxylup‐20(29)‐ene triterpene isolated from Combretum leprosum leaves in vivo and in silico approac	2
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Opening of mitochondrial permeability transition pore in cardiomyocytes: Is ferutinin a suitable tool for its assessment?	2
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Gout and Levodopa: An unknown adverse effect?	2
Orexin receptors: Targets and applications	2
Myrtenal exhibits cardioprotective effects by attenuating the pathological progression associated with myocardial infarction	2
Evidence that the anti‐inflammatory effect of 4‐aryl‐4H‐chromenes is linked to macrophage repolarization	2
Challenges and opportunities of medicines for treating tendon inflammation and fibrosis: A comprehensive and mechanistic review	2
Survey the effect of drug treatment on modulation of cytokines gene expression in allergic rhinitis	2
RETRACTION: Mineralocorticoid receptor antagonist‐mediated cognitive improvement in a mouse model of Alzheimer's type: possible involvement of BDNF‐H2S‐Nrf2 signaling	2
Wnt/beta‐catenin modulation: A promising frontier in chronic kidney disease management	2
Exogenous GalR2‐specific peptide agonist as a tool for treating myocardial ischemia/reperfusion injury	2
Discussed Poster Abstracts – PM1	2