Fundamental & Clinical Pharmacology

Article	Citations
Diarrhea and angiotensin II receptor blockers: Is there any difference between the different drugs?	64
Alamandin and especially melatonin attenuate pulmonary arterial hypertension induced by monocrotalin	59
Protective Effects of Cannabis sativa on chemotherapy‐induced nausea in a rat: Involvement of CB1 receptors	57
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Can cannabidiol have an analgesic effect?	31
In vitro evidence that the vasorelaxant effects of 2‐nitro‐1‐phenyl‐1‐propanol on rat coronary arteries involve cyclic nucleotide pathways	28
Inhibition of NorA efflux pump of Staphylococcus aureus by anacardic acids isolated from the cashew nutshell liquid of Anacardium occidentale L.	26
Effect of ceftriaxone on intestinal transit time	25
Calcium dobesilate protects against d‐galactose‐induced hepatic and renal dysfunction, oxidative stress, and pathological damage	22
MiR‐199a‐3p in mouse bone marrow mesenchymal stem cell exosomes increases epithelial sodium channel expression in lung injury	21
Novel ginsenoside monomer RT4 promotes colitis repair in mice by regulating miR‐144‐3p/SLC7A11 signaling pathway	20
Improvement of cognitive dysfunction by a novel phosphodiesterase type 5 inhibitor, Tadalafil	20
Effects of clarithromycin on the pharmacokinetics of tacrolimus and expression of CYP3A4 and P‐glycoprotein in rats	19
Methylsulfonylmethane induces caspase‐dependent apoptosis in acute myeloid leukemia cell lines	19
Effects of FECH Gene Polymorphisms and Serum Ferrochelatase Levels on Antituberculosis Drug‐Induced Liver Injury in China	18
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Precipitation of sugammadex with nicardipine and labetalol: A laboratory research	17
Relative bioavailability and pharmacokinetic comparison of a fixed‐dose combination tablet of mosapride, pancreatin, and simethicone relative to single‐component mosapride tablets in healthy Mexican s	17
Sakuranetin exerts anticonvulsant effect in bicuculline‐induced seizures	16
Issue Information	16
Evaluation of anti‐inflammatory activity of kaurenol: Experimental evaluation and mechanistic insights	15
Targeting autophagy with tamoxifen in breast cancer: From molecular mechanisms to targeted therapy	15
Cell therapy procedure using anti‐inflammatory macrophage M2 can potentially reduce Clinical Score in animals with Experimental Autoimmune Encephalomyelitis: A preclinical systematic review and meta‐a	14
Gemfibrozil, a lipid‐lowering drug, improves hepatorenal damages in a mouse model of aging	14
Treatment implications of augmented renal clearance in a critically ill COVID‐19 patient: A case report	14

Repurposing of atorvastatin and metformin denotes their individual and combined antiproliferative effects in non‐small cell lung cancer	14
Master 2 Award	13
Cover Image, Volume 36, Issue 1	13
Metformin improves neurobehavioral impairments of streptozotocin‐treated and western diet‐fed mice: Beyond glucose‐lowering effects	13
Issue Information	13
Histamine H1‐ and H2‐receptors participate to provide metabolic energy differently	12
Issue Information	12
Spontaneous reporting of adverse drug reactions as an outlet for patient dismay? The case of Levothyrox® change of excipients	11
Thesis awards	11
Vestibular disorders following BNT162b2 mRNA COVID‐19 vaccination: A retrospective case series	11
Chlorogenic acid co‐administration alleviates cisplatin‐induced peripheral neuropathy in rats	11
Population pharmacokinetics of mycophenolate in patients treated for interstitial lung disease (EVER‐ILD study)	11
Acetazolamide suppresses the progression of hepatocellular carcinoma induced by diethylnitrosamine in Wistar albino rats	11
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UPLC‐MS analysis and network pharmacology‐based investigation into the active ingredients and molecular mechanisms of anti‐fatigue of male flowers with Eucommia ulmoides Oliv.	10
Issue Information	10
Sitagliptin's renoprotective effect in a diabetic nephropathy model in rats: The potential role of PI3K/AKT pathway	10
Oxidative stress and mitochondrial dysfunction following traumatic brain injury: From mechanistic view to targeted therapeutic opportunities	10
Master 2 award	10
Vitamin D lacks efficacy: A re‐analysis of a systematic review using the REB method	9
A comprehensive view on the quercetin impact on bladder cancer: Focusing on oxidative stress, cellular, and molecular mechanisms	9
Therapeutic targeting of DNA damage repair pathways guided by homologous recombination deficiency scoring in ovarian cancers	9
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Inhibition of plasminogen suppresses fibrosis and macrophage foaming in a nonalcoholic steatohepatitis mouse model	9
A novel naphthylchalcone ([E]‐4‐(3‐[naphthalen‐2‐yl]‐3‐oxoprop‐1‐en‐1‐yl) induces intrinsic and extrinsic apoptosis in human acute leukemia cell lines	9
Differential expression and activities of cytochrome P450 3A in the rat brain microsomes and mitochondria	9
Use of real‐world evidence in translational pharmacology research	9
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Issue Information	9
Theme and main topic index	9
Capivasertib augments chemotherapy via Akt inhibition in preclinical small cell lung cancer models	9
Necrostatin‐1 attenuates oral squamous cell carcinoma by modulating tumour immune response in mice	9
The protective effect of 3‐indolepropanoic acid on aflatoxin B1‐induced systemic perturbation of the liver and kidney function in rats	9
Association between immune‐related adverse events and prognosis in patients treated with immune checkpoint inhibitors in melanoma: A surrogacy analysis	8
Inhibition of kidney potassium channels by fluoxetine: In vivo and in vitro studies	8
Effects of nalbuphine on the cardiotoxicity of ropivacaine in rats	8
Advances in the phytochemical screening and biological potential of propolis	8
Involvement of different K+ channel subtypes in hydrogen sulfide‐induced vasorelaxation of human internal mammary artery	8
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Anti‐oxidative and anti‐neuroinflammatory role of Necrostatin‐1s and docosahexaenoic acid in RIP‐1‐mediated neurotoxicity in MPTP‐induced Parkinson's disease model	8
Issue Information	8
Discussed Poster Abstracts – PM2	8
Effect of a high‐fat meal on the relative bioavailability of HMPL‐689 in Chinese healthy volunteers	8
Animal models for the evaluation of antipsychotic agents	8
Bupivacaine inhibits the TLR4‐ and TLR2‐Myd88/NF‐κB pathways in human leukocytes	8
Oral communication abstracts	8
Deliberation on debilitating condition of cancer cachexia: Skeletal muscle wasting	8
Prospective pilot study evaluating a vitamin D3 loading dose in critically ill children with vitamin D deficiency	7
Antihypertensive and lipid‐lowering drugs usage after primary stroke in a large representative sample of the French population	7
A systematic strategy for investigating the pharmacological effects and mechanism of traditional Chinese medicinal formula: Guilin Xiguashuang as a case	7

Lacosamide use during breastfeeding: A case report and a literature review	7
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Tamsulosin Attenuates Cardiac Hypertrophy via Integrin‐Linked Kinase: Possible Mechanisms	7
Drug‐induced radiation recall reactions and non‐anticancer drugs: A descriptive analysis from VigiBase®	7
Drug news and therapeutic news	7
Adrenaline enhances nociceptive and motor blockades by intrathecal carteolol and oxprenolol in rats	7
Atorvastatin ameliorates α‐KGDH and GDH functions in rats with diet‐induced hypercholesterolemia	7
Benzimidazole derivatives: A versatile scaffold for drug development against Helicobacter pylori‐related diseases	7
The effects of cannabidiol on subjective states, cognition, and psychomotor function in healthy adults: A randomized clinical trial	7
Discussed Poster Abstracts – PM1	7
Pharmacokinetic and pharmacodynamic study of three products of epoetin alfa as single subcutaneous dose in healthy volunteers	6
LQM10, a guanylhydrazone derivative, reduces nociceptive and inflammatory responses in mice	6
Nebivolol Mitigates the Pro‐Oxidative and Pro‐Inflammatory Effects of Cyclophosphamide in the Heart	6
Recognition of potential therapeutic role of 2‐hydroxy‐3‐methylanthraquinones in the treatment of gallbladder carcinoma: A proteomics analysis	6
Oral Communication Abstracts	6
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Potentiation of antibiotic activity, and efflux pumps inhibition by (2E)‐1‐(4‐aminophenyl)‐3‐(4‐fluorophenyl)prop‐2‐en‐1‐one	6
Inflammatory molecules facilitate the development of docetaxel‐resistant prostate cancer cells in vitro and in vivo	6
JAK/STAT inhibitors mitigate sepsis‐associated cerebral and cognitive injury	6
Borolatonin limits cognitive deficit and neuron loss while increasing proBDNF in ovariectomised rats	6
Prevalence of medication administration errors in hospitalized adults: A systematic review and meta‐analysis up to 2017 to explore sources of heterogeneity	6
Issue Information	6
Immunomodulator FTY720 improves glucose homeostasis and diabetic complications by rejuvenation of β‐cell function in nonhuman primate model of diabetes	6
Potentiating‐antibiotic activity and absorption, distribution, metabolism, excretion and toxicity properties (ADMET) analysis of synthetic thiadiazines against multi‐drug resistant (MDR) strains	6
Probing polypharmacy, ageing and sex effects on physical function using different tests	6
Update on monkeypox virus infection: Focusing current treatment and prevention approaches	6
The vascular impact of dapagliflozin, liraglutide, and atorvastatin alone or in combinations in type 2 diabetic rat model	6
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Master 2 award	6
Analgesic switching in chronic users of dextropropoxyphene in France	6
Relapse and New‐Onset of Autoimmune or Inflammatory Diseases Following Vaccination With SPIKEVAX: Pharmacovigilance Overview From the French Spontaneous Reported System	6
A mini‐review on anticancer‐related properties of azithromycin and its potential activities in overcoming the challenges of glioblastoma	5
Antimanic‐like effect of dipyridamole in the methylphenidate‐induced hyperlocomotion	5
Insights into nanostructured lipid carriers of etoricoxib for mitigating radiation‐induced lung inflammation and exploring anti‐inflammatory mechanisms in rats	5
Population pharmacokinetics of sivelestat in Chinese patients with severe pneumonia	5
Immunomodulatory effect of IL‐35 gene‐transfected mesenchymal stem cells on allergic asthma	5
Thesis awards	5
Mechanism research on microRNA‐669f‐5p/deoxycytidylate deaminase axis mediating sevoflurane‐induced cognitive dysfunction in aged mice	5
Drug news and therapeutic news	5
Statins as Antifungal Agents: A Review on Drug Repurposing and Nanotechnology‐Driven Delivery Strategies	5
Second primary cancers and hormonal therapies for prostate cancer: A nested case–control study	5
ADMET study, spectroscopic characterization and effect of synthetic nitro chalcone in combination with norfloxacin, ciprofloxacin, and ethidium bromide against Staphylococcus aureus	5
Angiotensin receptor–neprilysin inhibitor (thiorphan/irbesartan) improved cardiac function in a rat model of myocardial ischemic reperfusion injury	5
Development of a Bayesian estimation tool to determine the optimal duration of apixaban discontinuation before a high‐bleeding risk procedure	5
Afatinib triggers a Ni2+‐resistant Ca2+ influx pathway in A549 non‐small cell lung cancer cells	5
Vortioxetine improved schizophrenia‐like behavioral deficits in a Poly I:C‐induced maternal immune activation model of schizophrenia in rats	5
Edaravone dexborneol protects cerebral ischemia reperfusion injury through activating Nrf2/HO‐1 signaling pathway in mice	5
Latest advances in the reversal strategies for direct oral anticoagulants	4
Issue Information	4
In vitro evidence that the anti‐inflammatory effect of synthetic cinnamate‐derived dienes is directly linked to a macrophage repolarization	4
Antinociceptive, anxiolytic, and depression‐like effects of hydrogen sulfide, nitric oxide, and carbon monoxide in rats and the role of opioidergic and serotonergic systems in antinociceptive activity	4
Busulfan induces steatosis in HepaRG cells but not in primary human hepatocytes: Possible explanations and implication for the prediction of drug‐induced liver injury	4
The role of β‐adrenergic receptors in the regulation of cardiac tolerance to ischemia/reperfusion. Why do β‐adrenergic receptor agonists and antagonists protect the heart?	4
Pro‐inflammatory cytokines mediating senescence of vascular endothelial cells in atherosclerosis	4
Trends in adverse drug reactions related to oral weak opioid analgesics in therapeutic use in adults: A 10‐year French vigilances retrospective study	4
Issue Information	4
Issue Information	4
No Impact of Vancomycin MIC, AUC, or AUC/MIC in Enterococcus faecium Bacteremia	4
Prognostic roles of dysregulated METTL3 protein expression in cancers and potential anticancer value by inhibiting METTL3 function	4
Fundamental and Clinical Pharmacology of drug repositioning	4
Fluvoxamine Attenuates Liver Injury in Lipopolysaccharide‐Induced Sepsis: Via Nrf2/HO‐1 Pathway	4
Discussed poster abstracts—PM1	4
Interaction of buspirone and its major metabolites with human organic cation transporters	4
Knockdown of RFC3 enhances the sensitivity of colon cancer cells to oxaliplatin by inducing ferroptosis	4
Is lithium neuroprotective? An updated mechanistic illustrated review	4
Issue Information	4
Pharmacological treatment for mental health illnesses in adults receiving dialysis: A scoping review	4
(−)‐Epicatechin improves body composition of male rats descendant of obese mothers postnatally fed with a high‐fat diet	4
Cannabinoids and Adverse Convulsive Effects: A Pharmacovigilance and Addictovigilance Analysis of Cases Reported in France	4
KATP channels are regulators of programmed cell death and targets for the creation of novel drugs against ischemia/reperfusion cardiac injury	4
Drug Exposure in Chronic Kidney Disease: It Is Not Just About the Glomerular Filtration Rate	3
Evaluation of potential antiviral activities of antimicrobial peptides in fish mucus	3
Glibenclamide promoted functional recovery following sciatic nerve injury in male Wistar rats	3
Issue Information	3
Investigating the link between drug consumption and adverse events reporting in France	3
Issue Information	3
Effects of the nerve growth factor and its carrier protein on the inflammatory response from human monocytes	3
Role of biomarkers and molecular signaling pathways in acute lung injury	3
Exploring the therapeutic potential of Modafinil in mitigating renal ischemia–reperfusion injury in rats	3

Physiologically Based Pharmacokinetic modelling of drugs in pregnancy: A mini‐review on availability and limitations	3
The protective effect of pregabalin and xanthenone on testicular ischemia/reperfusion injury in rats	3
Telmisartan: An angiotensin receptor blocker regulates osteoclastogenesis via inhibition of the ERK triggering in osteoporotic male rats	3
Pre‐treatment or post‐treatment with hydroxychloroquine demonstrates neuroprotective effects in cerebral ischemia/reperfusion	3
Correction to “ABCB1, SLC22A1, COMT, and OPRM1 Genotypes: Study of Their Influence on Plasma Methadone Levels and Clinical Response to Methadone Maintenance Treatment in Op	3
Intradermal testing of iodinated contrast media: Should we test up to pure or with diluted compounds only?	3
Pentosan polysulfate exerts anti‐inflammatory effect and halts albuminuria progression in diabetic nephropathy: Role of combined losartan	3
FKA‐A NPs enhances PTX‐A NPs efficacy to suppress ovarian cancer via regulating Skp2/YAP pathway	3
Theme and main topic index	3
Sodium‐glucose cotransporter‐2 inhibitor (SGLT2i) plus glucagon‐like peptide type 1 receptor combination is more effective than SGLT2i plus dipeptidyl peptidase‐4 inhibitor combination in treating obe	3
Discussed Poster Abstracts	3
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Heterogeneity in protocols and outcomes to study the effect of renin‐angiotensin system blockers in inflammatory bowel disease: A systematic review	3
Author index	3
Hesperidin improves physiological outcomes in an arginine vasopressin rat model of pre‐eclampsia	3
Photobiological effect of eugenol‐derived 3‐benzoylcoumarin associated with led lights against MDR microorganisms	3
Issue Information	3
Bezafibrate mitigates oxidized‐low density lipoprotein (ox‐LDL)‐induced the attachment of monocytes to endothelial cells: An implication in atherosclerosis	3
DPD Ultra‐Rapid Metabolizer Status and Efficacy of 5‐Fluorouracil Treatment: A Real‐World Study	3
Advances on pharmacology and toxicology of aconitine	3
Repurposing Asparaginase Therapy to Target Cisplatin‐Resistant Cancer Cells	3
Issue Information	3
Alterations in the gene expression of SARS‐COV‐2 entry receptors and enzymes in lungs and hearts of controlled and uncontrolled diabetic mice	3
MNK/eIF4E inhibition overcomes anlotinib resistance in non‐small cell lung cancer	2
Myrtenal exhibits cardioprotective effects by attenuating the pathological progression associated with myocardial infarction	2
Issue Information	2
Issue Information	2
Inhibitory effects and molecular mechanisms of ginsenoside Rg1 on the senescence of hematopoietic stem cells	2
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Isobolographic analysis of the ciprofloxacin–gentamicin combination against beta‐lactamase‐producing Staphylococcus aureus	2
Breastfeeding and contrast agents—A critical review and presentation of new aspects	2
Hypoglycemic effect on adult zebrafish (Danio rerio) of the 3β‐6β‐16β‐trihydroxylup‐20(29)‐ene triterpene isolated from Combretum leprosum leaves in vivo and in silico approac	2
Chemsex in HIV pre‐exposure prophylaxis users: Assessment of mood disorders and addictive behavior	2
Effects of acute ethanol and/or diazepam exposure on immediate and delayed hippocampal metabolite levels in rats anesthetized with isoflurane	2
Sodium hypochlorite accident diagnosis and management: Analysis from the literature and the French pharmacovigilance database	2
Immunomodulatory effect of N‐acetyl‐seryl‐aspartyl‐proline and vasoactive intestinal peptide on chronic obstructive pulmonary disease pathophysiology	2
Molecular mechanisms of Alzheimer's disease: From therapeutic targets to promising drugs	2
Exogenous GalR2‐specific peptide agonist as a tool for treating myocardial ischemia/reperfusion injury	2
Activation of spinal ephrin‐B3/EphBs signaling induces hyperalgesia through a PLP‐mediated mechanism	2
Challenges and opportunities of medicines for treating tendon inflammation and fibrosis: A comprehensive and mechanistic review	2
The synergy between alkylating agents and ERCC1–XPF inhibitors is p53 dependent	2
Induction of Ca2+ signaling and cytotoxic responses of human lung fibroblasts upon an antihistamine drug oxatomide treatment and evaluating the protective effects of Ca2+ chelati	2
Issue Information	2
Repurposing bosentan as an anticancer agent: EGFR/ERK/c‐Jun modulation inhibits NSCLC tumor growth	2
Opening of mitochondrial permeability transition pore in cardiomyocytes: Is ferutinin a suitable tool for its assessment?	2
Dual ETA‐ETB receptor antagonism improves metabolic syndrome‐induced heart failure with preserved ejection fraction	2
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Discussed Poster Abstracts – PM1	2
Role of apoptosis and autophagy in folic acid‐induced cytotoxicity of human breast cancer cells in vitro	2
Effect of spermidine on long non‐coding RNAs MALAT1 in a rotenone induced‐rat model of Parkinson's disease	2
Wnt/beta‐catenin modulation: A promising frontier in chronic kidney disease management	2
Role of angiotensin receptor blockers in the context of Alzheimer's disease	2
Leveraging Fiber Photometry to Decipher Neural Circuits Underlying Anxiety in Mice	2
The state of astragaloside IV research: A bibliometric and visualized analysis	2
Evidence that the anti‐inflammatory effect of 4‐aryl‐4H‐chromenes is linked to macrophage repolarization	2