Fundamental & Clinical Pharmacology

Papers
(The TQCC of Fundamental & Clinical Pharmacology is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)
ArticleCitations
Chemsex practice in France: An update in Addictovigilance data32
Hepatoprotective and therapeutic effects of resveratrol: A focus on anti‐inflammatory and antioxidative activities32
Antiviral therapies: advances and perspectives30
Potential drug–drug interactions associated with drugs currently proposed for COVID‐19 treatment in patients receiving other treatments30
Oral drug delivery with nanoparticles into the gastrointestinal mucosa30
Poster Abstracts28
Poster Abstracts28
Melatonin and morphine: potential beneficial effects of co‐use28
A systematic review of experimental evidence for antiviral effects of ivermectin and an in silico analysis of ivermectin's possible mode of action against SARS‐CoV‐228
Sildenafil beyond erectile dysfunction and pulmonary arterial hypertension: Thinking about new indications26
Oxidative stress and mitochondrial dysfunction following traumatic brain injury: From mechanistic view to targeted therapeutic opportunities25
Progress on ocular siRNA gene‐silencing therapy and drug delivery systems25
In vitro inhibition and molecular docking of a new ciprofloxacin‐chalcone against SARS‐CoV‐2 main protease24
Omentin‐1 attenuates adipose tissue inflammation via restoration of TXNIP/NLRP3 signaling in high‐fat diet‐induced obese mice23
Neuropharmacology in traumatic brain injury: from preclinical to clinical neuroprotection?23
Edaravone dexborneol protects cerebral ischemia reperfusion injury through activating Nrf2/HO‐1 signaling pathway in mice22
Differential effects of alliin and allicin on apoptosis and senescence in luminal A and triple‐negative breast cancer: Caspase, ΔΨm, and pro‐apoptotic gene involvement21
Genesis of an emergency public drug information website by the French Society of Pharmacology and Therapeutics during the COVID‐19 pandemic21
Targeting Wnt/β‐catenin by anthelmintic drug niclosamide overcomes paclitaxel resistance in esophageal cancer19
Sumatriptan reduces severity of status epilepticus induced by lithium–pilocarpine through nitrergic transmission and 5‐HT1B/D receptors in rats: A pharmacological‐based evidence19
Novel potential of metformin on valproic acid‐induced autism spectrum disorder in rats: involvement of antioxidant defence system18
Valproic acid reverses sorafenib resistance through inhibiting activated Notch/Akt signaling pathway in hepatocellular carcinoma18
The clinical meaning of levodopa equivalent daily dose in Parkinson's disease18
Anti‐inflammatory effect of amitriptyline in a rat model of acetic acid‐induced colitis: the involvement of the TLR4/NF‐kB signaling pathway17
Ceftriaxone‐associated biliary pseudolithiasis in children: do we know enough?17
Poster Abstracts17
The possible role of CREB‐BDNF signaling pathway in neuroprotective effects of minocycline against alcohol‐induced neurodegeneration: molecular and behavioral evidences16
Mineralocorticoid receptor antagonist‐mediated cognitive improvement in a mouse model of Alzheimer's type: possible involvement of BDNF‐H2S‐Nrf2 signaling16
Remdesivir potently inhibits carboxylesterase‐2 through covalent modifications: signifying strong drug‐drug interactions16
Psychoactive substance use among students: A cross‐sectional analysis16
Protective effect of fenofibrate against high‐fat–high‐fructose diet induced non‐obese NAFLD in rats16
Exploring the beneficial role of ROCK inhibitors in sepsis‐induced cerebral and cognitive injury in rats16
Health consequences of cocaine use in France: data from the French Addictovigilance Network15
Is lithium neuroprotective? An updated mechanistic illustrated review14
Outcome of patients hospitalized for COVID‐19 and exposure to angiotensin‐converting enzyme inhibitors and angiotensin‐receptor blockers in France: results of the ACE‐CoV study14
Comparison of the effects of losartan, captopril, angiotensin II type 2 receptor agonist compound 21, and MAS receptor agonist AVE 0991 on myocardial ischemia–reperfusion necrosis in rats14
Targeting IL‐10, ZO‐1 gene expression and IL‐6/STAT‐3 trans‐signaling by a combination of atorvastatin and mesalazine to enhance anti‐inflammatory effects and attenuates progression of oxazolone‐induc13
Evaluation of the neuroprotective effect of donepezil in type 2 diabetic rats12
Development of pyrazole derivatives in the management of inflammation12
The contributions of metabolomics in the discovery of new therapeutic targets in Alzheimer's disease11
Rapamycin attenuates depression and anxiety‐like behaviors through modulation of the NLRP3 pathway in pentylenetetrazole‐kindled male Wistar rats11
Pharmacological agents under investigation in the treatment of coronavirus disease 2019 and the importance of melatonin11
Is the mechanism of action of antiseizure drugs a key element in the choice of treatment?11
Melatonin has an inhibitory effect on MCF‐7 and MDA‐MB‐231 human breast cancer cell lines by inducing autophagy and apoptosis11
Ivabradine improves survival and attenuates cardiac remodeling in isoproterenol‐induced myocardial injury10
Impact of bariatric surgery on oral anticoagulants pharmacology, and consequences for clinical practice: a narrative review10
Dexamethasone and p38 MAPK inhibition of cytokine production from human lung fibroblasts10
An overview of ongoing clinical trials assessing pharmacological therapeutic strategies to manage chemotherapy‐induced peripheral neuropathy, based on preclinical studies in rodent models10
N‐(benzylidene)‐2‐((2‐hydroxynaphthalen‐1‐yl)diazenyl)benzohydrazides (1‐2) (NCHDH and NTHDH) attenuate DMBA‐induced breast cancer via Nrf2/NF‐κB/apoptosis signaling10
Fentanyl inhibits acute myeloid leukemia differentiated cells and committed progenitors via opioid receptor‐independent suppression of Ras and STAT5 pathways10
Drug adulteration of sexual enhancement supplements: a worldwide insidious public health threat10
Angiotensin aldosterone inhibitors improve survival and ameliorate kidney injury induced by sepsis through suppression of inflammation and apoptosis10
Safety concerns on the abuse potential of esketamine: Multidimensional analysis of a new anti‐depressive drug on the market9
Abemaciclib sensitizes HPV‐negative cervical cancer to chemotherapy via specifically suppressing CDK4/6‐Rb‐E2F and mTOR pathways9
Overview of French databases available for studying anticancer drugs in real‐life setting9
Inhibition of organic cation transporter 3 activity by tyrosine kinase inhibitors9
Doctor shopping for methylphenidate as a proxy for misuse and potential abuse in the 67 million inhabitants in France9
Antidepressants with anti‐tumor potential in treating glioblastoma: A narrative review9
Lacosamide improves biochemical, genotoxic, and mitochondrial parameters after PTZ‐kindling model in mice9
Bisoprolol, a β1 antagonist, protects myocardial cells from ischemia–reperfusion injury via PI3K/AKT/GSK3β pathway9
Plasma gonadotropin levels in metformin‐treated men with prediabetes: a non‐randomized, uncontrolled pilot study9
Improvement of cognitive function, glucose and lipid homeostasis and serum osteocalcin levels by liraglutide in diabetic rats8
The HIV reverse transcriptase Inhibitor Tenofovir suppressed DMH/HFD‐induced colorectal cancer in Wistar rats8
COVID‐19 in DMARD‐treated patients with inflammatory rheumatic diseases: Insights from an analysis of the World Health Organization pharmacovigilance database8
Gemfibrozil, a lipid‐lowering drug, reduces anxiety, enhances memory, and improves brain oxidative stress in d‐galactose‐induced aging mice8
Benzimidazole derivatives: A versatile scaffold for drug development against Helicobacter pylori‐related diseases8
Impact of interleukin‐6 on drug transporters and permeability in the hCMEC/D3 blood–brain barrier model8
Homoarginine in the cardiovascular system: Pathophysiology and recent developments8
Tyrosine kinase inhibitors and direct oral anticoagulants: In vitro evaluation of drug–drug interaction mediated by P‐glycoprotein7
KATP channels are regulators of programmed cell death and targets for the creation of novel drugs against ischemia/reperfusion cardiac injury7
NVX‐Cov2373 Novavax Covid‐19 vaccine: A further analysis of its efficacy using multiple modes of expression7
Vortioxetine as an analgesic in preclinical inflammatory pain models: Mechanism of action7
Medication non‐adherence after allogeneic hematopoietic cell transplantation in adult and pediatric recipients: a cross sectional study conducted by the Francophone Society of Bone Marrow Transplantat7
Safety profile of hydroxychloroquine used off‐label for the treatment of patients with COVID‐19: A descriptive study based on EudraVigilance data7
Are potentially inappropriate and anticholinergic medications being prescribed for institutionalized elderly subjects?7
Study of prescription‐indication of tetracyclines in a population in Colombia7
Anisomycin sensitizes non‐small‐cell lung cancer cells to chemotherapeutic agents and epidermal growth factor receptor inhibitor via suppressing PI3K/Akt/mTOR7
Advances on pharmacology and toxicology of aconitine7
Effect of sacubitril/valsartan on cognitive impairment in colchicine‐induced Alzheimer's model in rats7
Targeting cannabinoid receptor 2 (CB2) limits collagen production—An in vitro study in a primary culture of human fibroblasts6
Potential drug–drug interactions associated with drugs currently proposed for COVID‐19 treatment in patients receiving other treatments6
Orexin receptors: Targets and applications6
Na+, K+‐ATPase participates in the protective mechanism of rat cerebral ischemia‐reperfusion through the interaction with glutamate transporter‐16
The PI3Kγ/AKT signaling pathway mediates peripheral antinociceptive action of dipyrone6
Antihyperlipidemic effect of selected pyrimidine derivatives mediated through multiple pathways6
Spermidine reduced neuropathic pain in chronic constriction injury‐induced peripheral neuropathy in rats6
Inhibition MNK‐eIF4E‐β‐catenin preferentially sensitizes gastric cancer to chemotherapy6
Short‐chain fatty acids increase intracellular calcium levels and enhance gut hormone release from STC‐1 cells via transient receptor potential Ankyrin16
Cluster headache: state of the art of pharmacological treatments and therapeutic perspectives6
Increased risk of urinary tract infection and pyelonephritis under concomitant use of sodium‐dependent glucose cotransporter 2 inhibitors with antidiabetic, antidyslipidemic, and antihypertensive drug6
Effects of physical activity on cell‐to‐cell communication during type 2 diabetes: A focus on miRNA signaling6
Vasorelaxant effect of trans‐4‐chloro‐β‐nitrostyrene, a synthetic nitroderivative, in rat thoracic aorta6
Function of intestinal barrier protected by regulating the miR‐199a‐3p in ulcerative colitis: Modulation of IL‐23/IL‐17A axis6
Antibiotics with therapeutic effects on spinal cord injury: a review6
Can chronopharmacology improve the therapeutic management of neurological diseases?6
Viral target and metabolism‐based rationale for combined use of recently authorized small molecule COVID‐19 medicines: Molnupiravir, nirmatrelvir, and remdesivir6
Effect of dapagliflozin and/or L‐arginine on solid tumor model in mice: The interaction between nitric oxide, transforming growth factor‐beta 1, autophagy, and apoptosis6
Immunomodulatory effect of IL‐35 gene‐transfected mesenchymal stem cells on allergic asthma6
Ameliorative effect of ozagrel, a thromboxane A2 synthase inhibitor, in hyperhomocysteinemia‐induced experimental vascular cognitive impairment and dementia6
Evaluating and modulating TFEB in the control of autophagy: toward new treatments in CNS disorders6
Xanthotoxin enhances the anticonvulsant potency of levetiracetam and valproate in the 6‐Hz corneal stimulation model in mice6
Effects of 27 CYP3A4 protein variants on saxagliptin metabolism in vitro5
Impact of anesthetics on oncogenic signaling network: a review on propofol and isoflurane5
An insight into the pharmacological and analytical potential of Andrographolide5
Adverse effects of gender‐affirming hormonal therapy in transgender persons: Assessing reports in the French pharmacovigilance database5
Efficacy of COVID‐19 vaccines: Several modes of expression should be presented in scientific publications5
Chemsex in HIV pre‐exposure prophylaxis users: Assessment of mood disorders and addictive behavior5
Ten‐year trends in hospitalizations related to cocaine abuse in France5
Tramadol‐induced hypoglycemia: A pharmacovigilance study5
Phosphatidylinositol 3‐kinase signaling pathway and inflammatory bowel disease: Current status and future prospects5
The vascular impact of dapagliflozin, liraglutide, and atorvastatin alone or in combinations in type 2 diabetic rat model5
Lacosamide‐induced personality changes: An unexpected adverse effect5
Absence of ethnic difference on single‐dose pharmacokinetics of rivoceranib between healthy male Caucasian, Japanese, and Chinese subjects5
The cyclin‐dependent kinase inhibitor AT7519 augments cisplatin's efficacy in ovarian cancer via multiple oncogenic signaling pathways5
The protective effect of 3‐indolepropanoic acid on aflatoxin B1‐induced systemic perturbation of the liver and kidney function in rats5
Ferulic acid mitigates diabetic cardiomyopathy via modulation of metabolic abnormalities in cardiac tissues of diabetic rats5
Variability of rituximab and tocilizumab trough concentrations in patients with rheumatoid arthritis5
Simvastatin–Ezetimibe enhances growth factor expression and attenuates neuron loss in the hippocampus in a model of intracerebral hemorrhage5
Activation of the Mas receptors by AVE0991 and MrgD receptor using alamandine to limit the deleterious effects of Ang II‐induced hypertension5
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