OOIR: Observatory of International Research

Papers

(The TQCC of Fundamental & Clinical Pharmacology is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
Diarrhea and angiotensin II receptor blockers: Is there any difference between the different drugs?	52
In vitro evidence that the vasorelaxant effects of 2‐nitro‐1‐phenyl‐1‐propanol on rat coronary arteries involve cyclic nucleotide pathways	52
Can cannabidiol have an analgesic effect?	51
Alamandin and especially melatonin attenuate pulmonary arterial hypertension induced by monocrotalin	48
Protective Effects of Cannabis sativa on chemotherapy‐induced nausea in a rat: Involvement of CB1 receptors	37
Location matters: Overlooked ethnic‐geographic effect in China and Austria on propofol/cisatracurium sex differences among a population pharmacokinetic/pharmacodynamic (PopPK/PD) covariate analysis in	31
Inhibition of NorA efflux pump of Staphylococcus aureus by anacardic acids isolated from the cashew nutshell liquid of Anacardium occidentale L.	28
Efficacy of COVID‐19 vaccines: Several modes of expression should be presented in scientific publications	27
Effect of ceftriaxone on intestinal transit time	27
Effects of clarithromycin on the pharmacokinetics of tacrolimus and expression of CYP3A4 and P‐glycoprotein in rats	23
Calcium dobesilate protects against d‐galactose‐induced hepatic and renal dysfunction, oxidative stress, and pathological damage	20
Novel ginsenoside monomer RT4 promotes colitis repair in mice by regulating miR‐144‐3p/SLC7A11 signaling pathway	17
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MiR‐199a‐3p in mouse bone marrow mesenchymal stem cell exosomes increases epithelial sodium channel expression in lung injury	17
Roflumilast improves resolution of sepsis‐induced acute kidney injury by retarding late phase renal interstitial immune cells infiltration and leakage in urinary sediments	17
Improvement of cognitive dysfunction by a novel phosphodiesterase type 5 inhibitor, Tadalafil	17
Methylsulfonylmethane induces caspase‐dependent apoptosis in acute myeloid leukemia cell lines	17
In vitro inhibition and molecular docking of a new ciprofloxacin‐chalcone against SARS‐CoV‐2 main protease	16
The protective effect of α7‐nACh receptor and its interaction with 5‐HT1B/1D receptors in acute intestinal ischemia‐reperfusion injury in rats	15
Tofacitinib improved peripheral endothelial dysfunction and brain‐derived neurotrophic factor levels in the rat adjuvant‐induced arthritis model	15
Sakuranetin exerts anticonvulsant effect in bicuculline‐induced seizures	14
Relative bioavailability and pharmacokinetic comparison of a fixed‐dose combination tablet of mosapride, pancreatin, and simethicone relative to single‐component mosapride tablets in healthy Mexican s	14
Cell therapy procedure using anti‐inflammatory macrophage M2 can potentially reduce Clinical Score in animals with Experimental Autoimmune Encephalomyelitis: A preclinical systematic review and meta‐a	13
Gemfibrozil, a lipid‐lowering drug, improves hepatorenal damages in a mouse model of aging	12
Metformin improves neurobehavioral impairments of streptozotocin‐treated and western diet‐fed mice: Beyond glucose‐lowering effects	12

Precipitation of sugammadex with nicardipine and labetalol: A laboratory research	12
Repurposing of atorvastatin and metformin denotes their individual and combined antiproliferative effects in non‐small cell lung cancer	12
Treatment implications of augmented renal clearance in a critically ill COVID‐19 patient: A case report	12
Evaluation of anti‐inflammatory activity of kaurenol: Experimental evaluation and mechanistic insights	12
Issue Information	11
Master 2 Award	11
Cover Image, Volume 36, Issue 1	11
Issue Information	11
Issue Information	11
Targeting autophagy with tamoxifen in breast cancer: From molecular mechanisms to targeted therapy	11
Histamine H1‐ and H2‐receptors participate to provide metabolic energy differently	10
Acetazolamide suppresses the progression of hepatocellular carcinoma induced by diethylnitrosamine in Wistar albino rats	10
Spontaneous reporting of adverse drug reactions as an outlet for patient dismay? The case of Levothyrox® change of excipients	10
Vestibular disorders following BNT162b2 mRNA COVID‐19 vaccination: A retrospective case series	10
UPLC‐MS analysis and network pharmacology‐based investigation into the active ingredients and molecular mechanisms of anti‐fatigue of male flowers with Eucommia ulmoides Oliv.	10
Population pharmacokinetics of mycophenolate in patients treated for interstitial lung disease (EVER‐ILD study)	10
Oxidative stress and mitochondrial dysfunction following traumatic brain injury: From mechanistic view to targeted therapeutic opportunities	9
Issue Information	9
Discussed Poster Abstracts	9
Chlorogenic acid co‐administration alleviates cisplatin‐induced peripheral neuropathy in rats	9
	9
Sitagliptin's renoprotective effect in a diabetic nephropathy model in rats: The potential role of PI3K/AKT pathway	9
Issue Information	9
A comprehensive view on the quercetin impact on bladder cancer: Focusing on oxidative stress, cellular, and molecular mechanisms	8
Inhibition of plasminogen suppresses fibrosis and macrophage foaming in a nonalcoholic steatohepatitis mouse model	8
Necrostatin‐1 attenuates oral squamous cell carcinoma by modulating tumour immune response in mice	8
Capivasertib augments chemotherapy via Akt inhibition in preclinical small cell lung cancer models	8
Therapeutic targeting of DNA damage repair pathways guided by homologous recombination deficiency scoring in ovarian cancers	8
Vitamin D lacks efficacy: A re‐analysis of a systematic review using the REB method	8
Use of real‐world evidence in translational pharmacology research	8
A novel naphthylchalcone ([E]‐4‐(3‐[naphthalen‐2‐yl]‐3‐oxoprop‐1‐en‐1‐yl) induces intrinsic and extrinsic apoptosis in human acute leukemia cell lines	8
Differential expression and activities of cytochrome P450 3A in the rat brain microsomes and mitochondria	8
Chemsex practice in France: An update in Addictovigilance data	8
The protective effect of 3‐indolepropanoic acid on aflatoxin B1‐induced systemic perturbation of the liver and kidney function in rats	8
	7
Animal models for the evaluation of antipsychotic agents	7
Effects of nalbuphine on the cardiotoxicity of ropivacaine in rats	7
Adrenaline enhances nociceptive and motor blockades by intrathecal carteolol and oxprenolol in rats	7
Antihypertensive and lipid‐lowering drugs usage after primary stroke in a large representative sample of the French population	7
Association between immune‐related adverse events and prognosis in patients treated with immune checkpoint inhibitors in melanoma: A surrogacy analysis	7
	7
Vitamin D3 potentiates the nephroprotective effects of vildagliptin–metformin combination in a rat model of metabolic syndrome	7
Anti‐oxidative and anti‐neuroinflammatory role of Necrostatin‐1s and docosahexaenoic acid in RIP‐1‐mediated neurotoxicity in MPTP‐induced Parkinson's disease model	7
Advances in the phytochemical screening and biological potential of propolis	7
	7
Benzimidazole derivatives: A versatile scaffold for drug development against Helicobacter pylori‐related diseases	7
	7
Inhibition of kidney potassium channels by fluoxetine: In vivo and in vitro studies	7
Bupivacaine inhibits the TLR4‐ and TLR2‐Myd88/NF‐κB pathways in human leukocytes	7
Discussed Poster Abstracts – PM2	7

Effect of a high‐fat meal on the relative bioavailability of HMPL‐689 in Chinese healthy volunteers	7
Prospective pilot study evaluating a vitamin D3 loading dose in critically ill children with vitamin D deficiency	7
Lacosamide use during breastfeeding: A case report and a literature review	6
Master 2 award	6
The effects of cannabidiol on subjective states, cognition, and psychomotor function in healthy adults: A randomized clinical trial	6
Chronic polypharmacy at all age: A population‐based drug utilization study	6
Deliberation on debilitating condition of cancer cachexia: Skeletal muscle wasting	6
Drug news and therapeutic news	6
Atorvastatin ameliorates α‐KGDH and GDH functions in rats with diet‐induced hypercholesterolemia	6
The vascular impact of dapagliflozin, liraglutide, and atorvastatin alone or in combinations in type 2 diabetic rat model	6
A systematic strategy for investigating the pharmacological effects and mechanism of traditional Chinese medicinal formula: Guilin Xiguashuang as a case	6
Recognition of potential therapeutic role of 2‐hydroxy‐3‐methylanthraquinones in the treatment of gallbladder carcinoma: A proteomics analysis	6
	6
Drug‐induced radiation recall reactions and non‐anticancer drugs: A descriptive analysis from VigiBase®	6
Discussed Poster Abstracts – PM1	6
Prevalence of medication administration errors in hospitalized adults: A systematic review and meta‐analysis up to 2017 to explore sources of heterogeneity	6
Involvement of different K⁺ channel subtypes in hydrogen sulfide‐induced vasorelaxation of human internal mammary artery	6
Update on monkeypox virus infection: Focusing current treatment and prevention approaches	6
Probing polypharmacy, ageing and sex effects on physical function using different tests	5
Borolatonin limits cognitive deficit and neuron loss while increasing proBDNF in ovariectomised rats	5
Issue Information	5
Analgesic switching in chronic users of dextropropoxyphene in France	5
Population pharmacokinetics of sivelestat in Chinese patients with severe pneumonia	5
Is lithium neuroprotective? An updated mechanistic illustrated review	5
Afatinib triggers a Ni²⁺‐resistant Ca²⁺ influx pathway in A549 non‐small cell lung cancer cells	5
Knockdown of RFC3 enhances the sensitivity of colon cancer cells to oxaliplatin by inducing ferroptosis	5
Pharmacokinetic and pharmacodynamic study of three products of epoetin alfa as single subcutaneous dose in healthy volunteers	5
JAK/STAT inhibitors mitigate sepsis‐associated cerebral and cognitive injury	5
Oral Communication Abstracts	5
Inflammatory molecules facilitate the development of docetaxel‐resistant prostate cancer cells in vitro and in vivo	5
Thesis awards	5
Immunomodulatory effect of IL‐35 gene‐transfected mesenchymal stem cells on allergic asthma	5
Development of a Bayesian estimation tool to determine the optimal duration of apixaban discontinuation before a high‐bleeding risk procedure	5
Second primary cancers and hormonal therapies for prostate cancer: A nested case–control study	5
Potentiation of antibiotic activity, and efflux pumps inhibition by (2E)‐1‐(4‐aminophenyl)‐3‐(4‐fluorophenyl)prop‐2‐en‐1‐one	5
LQM10, a guanylhydrazone derivative, reduces nociceptive and inflammatory responses in mice	5
Potentiating‐antibiotic activity and absorption, distribution, metabolism, excretion and toxicity properties (ADMET) analysis of synthetic thiadiazines against multi‐drug resistant (MDR) strains	5
	5
Immunomodulator FTY720 improves glucose homeostasis and diabetic complications by rejuvenation of β‐cell function in nonhuman primate model of diabetes	5
ADMET study, spectroscopic characterization and effect of synthetic nitro chalcone in combination with norfloxacin, ciprofloxacin, and ethidium bromide against Staphylococcus aureus	5
Angiotensin receptor–neprilysin inhibitor (thiorphan/irbesartan) improved cardiac function in a rat model of myocardial ischemic reperfusion injury	5
A mini‐review on anticancer‐related properties of azithromycin and its potential activities in overcoming the challenges of glioblastoma	5
In vitro evidence that the anti‐inflammatory effect of synthetic cinnamate‐derived dienes is directly linked to a macrophage repolarization	5