Fundamental & Clinical Pharmacology

Papers
(The TQCC of Fundamental & Clinical Pharmacology is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)
ArticleCitations
A systematic strategy for investigating the pharmacological effects and mechanism of traditional Chinese medicinal formula: Guilin Xiguashuang as a case49
Diarrhea and angiotensin II receptor blockers: Is there any difference between the different drugs?49
Verapamil downregulates iron uptake and upregulates divalent metal transporter 1 expression in H9C2 cardiomyocytes45
Drug News and Therapeutic News44
Issue Information37
Relationship between common telomere length‐related genetic variations, telomere length, and risk of antituberculosis drug‐induced hepatotoxicity in Chinese Han population: As assessed for causality u29
Opening of mitochondrial permeability transition pore in cardiomyocytes: Is ferutinin a suitable tool for its assessment?28
Fluoxetine‐induced downregulation of circMap2k1 signaling cascade to improve neurological function after ischemic stroke27
The effect of microglial inhibition on the expression of BDNF, KCC2, and GABAA receptor before and after the establishment of CCI‐induced neuropathic pain model27
(−)‐Epicatechin improves body composition of male rats descendant of obese mothers postnatally fed with a high‐fat diet19
Issue Information17
Targeting cannabinoid receptor 2 (CB2) limits collagen production—An in vitro study in a primary culture of human fibroblasts17
Effects of RS17053 on α1‐adrenoceptors in rat vas deferens and aorta17
Towards therapeutic drug monitoring of mycophenolic acid in mucous membrane pemphigoid: A retrospective single‐centre study17
Effects of acute ethanol and/or diazepam exposure on immediate and delayed hippocampal metabolite levels in rats anesthetized with isoflurane16
Issue Information16
COVID‐19 in DMARD‐treated patients with inflammatory rheumatic diseases: Insights from an analysis of the World Health Organization pharmacovigilance database15
Sevoflurane and isoflurane anesthesia induce redox imbalance, but only sevoflurane impairs vascular contraction14
The N‐methyl‐D‐aspartate receptor antagonist ketamin exerts analgesic effects via modulation of the nitric oxide pathway14
Cover Image, Volume 36, Issue 614
Enhancement of nerve regeneration with nimodipine treatment after sciatic nerve injury13
Viral target and metabolism‐based rationale for combined use of recently authorized small molecule COVID‐19 medicines: Molnupiravir, nirmatrelvir, and remdesivir13
Human neutrophil elastase inhibitors: Classification, biological‐synthetic sources and their relevance in related diseases12
NVX‐Cov2373 Novavax Covid‐19 vaccine: A further analysis of its efficacy using multiple modes of expression11
Antihypertensive and lipid‐lowering drugs usage after primary stroke in a large representative sample of the French population11
Deliberation on debilitating condition of cancer cachexia: Skeletal muscle wasting10
Homoarginine in the cardiovascular system: Pathophysiology and recent developments10
The role of β‐adrenergic receptors in the regulation of cardiac tolerance to ischemia/reperfusion. Why do β‐adrenergic receptor agonists and antagonists protect the heart?10
Gout and Levodopa: An unknown adverse effect?10
The HIV reverse transcriptase Inhibitor Tenofovir suppressed DMH/HFD‐induced colorectal cancer in Wistar rats10
Melatonin has an inhibitory effect on MCF‐7 and MDA‐MB‐231 human breast cancer cell lines by inducing autophagy and apoptosis10
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Prospective pilot study evaluating a vitamin D3 loading dose in critically ill children with vitamin D deficiency10
Protective Effects of Cannabis sativa on chemotherapy‐induced nausea in a rat: Involvement of CB1 receptors10
Can cannabidiol have an analgesic effect?9
Repurposing bosentan as an anticancer agent: EGFR/ERK/c‐Jun modulation inhibits NSCLC tumor growth9
Changes in serotonin neurotransmission as assayed by microdialysis after acute, intermittent or chronic ethanol administration and withdrawal9
In vitro evidence that the vasorelaxant effects of 2‐nitro‐1‐phenyl‐1‐propanol on rat coronary arteries involve cyclic nucleotide pathways9
Orexin receptors: Targets and applications9
Dose‐dependent bidirectional pharmacological effects of vinorelbine‐based metronomic combination chemotherapy on tumor growth and metastasis and mechanisms in melanoma mouse model9
Changes in digoxin pharmacokinetics associated with hepatic P‐glycoprotein upregulation in rats with non‐alcoholic fatty liver disease8
Fundamental and Clinical Pharmacology of drug repositioning8
Location matters: Overlooked ethnic‐geographic effect in China and Austria on propofol/cisatracurium sex differences among a population pharmacokinetic/pharmacodynamic (PopPK/PD) covariate analysis in8
Effect of a high‐fat meal on the relative bioavailability of HMPL‐689 in Chinese healthy volunteers8
Discussed Poster Abstracts – PM27
Ursodeoxycholic acid for preventing parenteral nutrition‐associated cholestasis in neonates: A systematic review and meta‐analysis7
Author Index7
Antidiabetic omarigliptin dilates rabbit aorta by activating voltage‐dependent K+ channels and the sarco/endoplasmic reticulum Ca2+‐ATPase pump7
Benzimidazole derivatives: A versatile scaffold for drug development against Helicobacter pylori‐related diseases7
Evidence that the anti‐inflammatory effect of 4‐aryl‐4H‐chromenes is linked to macrophage repolarization7
Chemsex in HIV pre‐exposure prophylaxis users: Assessment of mood disorders and addictive behavior7
Involvement of different K+ channel subtypes in hydrogen sulfide‐induced vasorelaxation of human internal mammary artery7
The state of astragaloside IV research: A bibliometric and visualized analysis7
Issue Information7
Oral communication abstracts7
Targeting mevalonate pathway by zoledronate ameliorated pulmonary fibrosis in a rat model: Promising therapy against post‐COVID‐19 pulmonary fibrosis7
Theme and main topic index7
Nociceptive TRP channels function as molecular target for several antifungal drugs7
Prognostic roles of dysregulated METTL3 protein expression in cancers and potential anticancer value by inhibiting METTL3 function7
Evaluation of the anti‐inflammatory effect of 1,4‐dihydropyridine derivatives6
Discussed Poster Abstracts – PM16
Calcium dobesilate protects against d‐galactose‐induced hepatic and renal dysfunction, oxidative stress, and pathological damage6
Alamandin and especially melatonin attenuate pulmonary arterial hypertension induced by monocrotalin6
Effect of sacubitril/valsartan on cognitive impairment in colchicine‐induced Alzheimer's model in rats6
Antihyperlipidemic effect of selected pyrimidine derivatives mediated through multiple pathways6
Drug news and therapeutic news6
Adrenaline enhances nociceptive and motor blockades by intrathecal carteolol and oxprenolol in rats6
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Effect of food intake on the pharmacokinetics of rivoceranib in healthy subjects6
Dihydroartemisinin inhibits angiogenesis in breast cancer via regulating VEGF and MMP‐2/‐96
Isobolographic analysis of the ciprofloxacin–gentamicin combination against beta‐lactamase‐producing Staphylococcus aureus5
Wnt/beta‐catenin modulation: A promising frontier in chronic kidney disease management5
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Methylsulfonylmethane induces caspase‐dependent apoptosis in acute myeloid leukemia cell lines5
The effects of cannabidiol on subjective states, cognition, and psychomotor function in healthy adults: A randomized clinical trial5
Issue Information5
Diarrhoea with the angiotensin receptor neprilysin inhibitor sacubitril + valsartan: A pharmacovigilance study5
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Induction of Ca2+ signaling and cytotoxic responses of human lung fibroblasts upon an antihistamine drug oxatomide treatment and evaluating the protective effects of Ca2+ chelati5
Oral Communication Abstracts5
The synthesis and antineoplastic activities of thiaziridine, sulfidometylphosphonium, and dithiaphosphitane‐sulfide against the Ehrlich ascites carcinoma5
Effects of clarithromycin on the pharmacokinetics of tacrolimus and expression of CYP3A4 and P‐glycoprotein in rats5
Exogenous GalR2‐specific peptide agonist as a tool for treating myocardial ischemia/reperfusion injury5
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Oral Communication Abstracts5
Hypoglycemic effect on adult zebrafish (Danio rerio) of the 3β‐6β‐16β‐trihydroxylup‐20(29)‐ene triterpene isolated from Combretum leprosum leaves in vivo and in silico approac5
Characterization of benzodiazepine misuse and comorbidities in patients with alcohol use disorder5
Preclinical evidence of the anti‐inflammatory effect and toxicological safety of aryl‐cyclohexanone in vivo5
Issue Information5
Breastfeeding and contrast agents—A critical review and presentation of new aspects5
High glucose upregulates PAR‐1 in SH‐SY5Y cells via deficiency of miR‐20a and miR‐190a5
Improvement of cognitive dysfunction by a novel phosphodiesterase type 5 inhibitor, Tadalafil5
Drug‐induced radiation recall reactions and non‐anticancer drugs: A descriptive analysis from VigiBase®5
Doctor shopping for methylphenidate as a proxy for misuse and potential abuse in the 67 million inhabitants in France5
Bezafibrate mitigates oxidized‐low density lipoprotein (ox‐LDL)‐induced the attachment of monocytes to endothelial cells: An implication in atherosclerosis4
Update on monkeypox virus infection: Focusing current treatment and prevention approaches4
Efficacy of COVID‐19 vaccines: Several modes of expression should be presented in scientific publications4
Population pharmacokinetics and pharmacodynamics of nirmatrelvir in Chinese patients with COVID‐194
Lacosamide‐induced personality changes: An unexpected adverse effect4
Drug news and therapeutic news4
Novel ginsenoside monomer RT4 promotes colitis repair in mice by regulating miR‐144‐3p/SLC7A11 signaling pathway4
Lacosamide use during breastfeeding: A case report and a literature review4
Discussed Poster Abstracts – PM14
Inhibition MNK‐eIF4E‐β‐catenin preferentially sensitizes gastric cancer to chemotherapy4
Compound K: A systematic review of its anticancer properties and probable mechanisms4
MiR‐199a‐3p in mouse bone marrow mesenchymal stem cell exosomes increases epithelial sodium channel expression in lung injury4
Roflumilast improves resolution of sepsis‐induced acute kidney injury by retarding late phase renal interstitial immune cells infiltration and leakage in urinary sediments4
Inhibition of NorA efflux pump of Staphylococcus aureus by anacardic acids isolated from the cashew nutshell liquid of Anacardium occidentale L.4
Dosing‐time, feeding, and sex‐dependent variations of everolimus pharmacokinetics in mice4
Naphazoline and oxymetazoline are superior to epinephrine in enhancing the cutaneous analgesia of lidocaine in rats4
Angiotensin aldosterone inhibitors improve survival and ameliorate kidney injury induced by sepsis through suppression of inflammation and apoptosis4
Challenges and opportunities of medicines for treating tendon inflammation and fibrosis: A comprehensive and mechanistic review4
Melatonin as a complementary and prophylactic agent against COVID‐19 in high‐risk populations: A narrative review of recent findings from clinical and preclinical studies4
Molecular toxicological alterations in the mouse hearts induced by sub‐chronic thiazolidinedione drugs administration4
Effect of ceftriaxone on intestinal transit time4
An exploratory study of drug concentration and inhibitory effect of cetylpyridinium chloride buccal tablets on SARS‐CoV‐2 infection among 10 Chinese subjects4
Activation of the Mas receptors by AVE0991 and MrgD receptor using alamandine to limit the deleterious effects of Ang II‐induced hypertension4
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Antidepressants with anti‐tumor potential in treating glioblastoma: A narrative review4
FKA‐A NPs enhances PTX‐A NPs efficacy to suppress ovarian cancer via regulating Skp2/YAP pathway4
Effects of the nerve growth factor and its carrier protein on the inflammatory response from human monocytes4
Role of angiotensin receptor blockers in the context of Alzheimer's disease4
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