OOIR: Observatory of International Research

Papers

(The median citation count of Biochemistry and Cell Biology is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Maternal use of methamphetamine alters cardiovascular function in the adult offspring	23
Structure and function of fermentation-derived bovine lactoferrin produced from Komagataella phaffii	22
Introduction: Dual use in life science research	21
Retraction: Long noncoding RNA HIF1A-AS2 facilitates cell survival and migration by sponging miR-33b-5p to modulate SIRT6 expression in osteosarcoma	19
Retraction: PYGB facilitates cell proliferation and invasiveness in non-small cell lung cancer by activating the Wnt–β-catenin signaling pathway	18
Transcriptional regulation of human abraxas brother protein 1 expression by yin yang 1	18
Circ_0000043 promotes the proliferation, migration, invasiveness, and epithelial–mesenchymal transition in breast cancer cells via the miR-136–Smad3 axis	17
Retraction: MicroRNA-181 inhibits proliferation and promotes apoptosis of chondrocytes in osteoarthritis by targeting PTEN	15
Retraction: MiR-301b promotes the proliferation, mobility, and epithelial-to-mesenchymal transition of bladder cancer cells by targeting EGR1	15
Characterization of a novel FADS2 transcript variant: implications for D6D activity regulation in cells	14
Retraction: Lentivirus-mediated angiopoietin-2 gene silencing decreases TNF-α induced apoptosis of alveolar epithelium cells	14
The nuclear-localized GHR is involved in the cell proliferation of gastric cancer, and pegvisomant may be an important potential drug to inhibit the proliferation of gastric cancer cells	14
The m6A reader IGF2BP2 promotes the progression of esophageal squamous cell carcinoma cells by increasing the stability of OCT4 mRNA	13
Paeonol reduces IL-β production by inhibiting the activation of nucleotide oligomerization domain-like receptor protein-3 inflammasome and nuclear factor-κB in macrophages	13
HSPB8 facilitates prostate cancer progression via activating the JAK/STAT3 signaling pathway	13
Cadmium chloride generates cytotoxic reactive species that cause oxidative damage and morphological changes in human erythrocytes	12
NDUFA4 promotes the progression of head and neck paraganglioma by inhibiting ferroptosis	12
BioCanRx Summit for Cancer Immunotherapy 2022 Proceedings	12
Working from within: how secretory leukocyte protease inhibitor regulates the expression of pro-inflammatory genes	11
CD142 plays a key role in the carcinogenesis of gastric adenocarcinoma by inhibiting BCL2-dependent autophagy	11
Interaction between the guanylate kinase domain of PSD-95 and the proline-rich region and microtubule binding repeats 2 and 3 of tau	11
RNA deadenylation complexes in development and diseases	11
Exogenous hydrogen sulfide prevents SOD2 degradation to safeguard renal function in diabetic kidney disease	10
Message from Dr. Philippe T. Georgel, Guest Editor for the Marshall University Collection, Brad D. Smith, President of Marshall University, and Dr. Anivandan Mukherjee, Provost of Marshall University	10
FYCO1 regulates migration, invasion, and invadopodia formation in HeLa cells through CDC42/N-WASP/Arp2/3 signaling pathway	10

Comparative analysis of the effect of hypoxia in two different tumor cell models shows the differential involvement of PTEN control of proangiogenic pathways	10
G protein coupled receptor kinase 5 modifies the nucleolar stress response activated by actinomycin D	10
Effects of the omega-3 fatty acid DHA on histone and p53 acetylation in diffuse large B cell lymphoma	9
Doxorubicin, a DNA intercalator, inhibits transcription elongation	9
On-cell nuclear magnetic resonance spectroscopy to probe cell surface interactions	9
Resveratrol upregulates miR-455-5p to antagonize cisplatin ototoxicity via modulating the PTEN–PI3K–AKT axis	9
SOAT1 enhances lung cancer invasiveness by stimulating AKT-mediated mitochondrial fragmentation	8
Aberrant sphingomyelin³¹P-NMR signatures in giant cell tumour of bone	8
Tetraspanin-29 activates Notch signaling by interacting with ADAM10 to enhance its activity in colorectal cancer	8
Effects of clopidogrel bisulfate on B16-F10 cells and tumor development in a murine model of melanoma	8
Cholecalciferol induces apoptosis via autocrine metabolism in epidermoid cervical cancer cells	8
Chromatin- and nucleosome-associated features in liquid biopsy: implications for cancer biomarker discovery	8
Saikosaponin-d protects against liver fibrosis by regulating the estrogen receptor-β/NLRP3 inflammasome pathway	8
Thidiazuron suppresses breast cancer via targeting miR-132 and dysregulation of the PI3K–Akt signaling pathway mediated by the miR-202-5p–PTEN axis	8
Hoxa5 inhibits adipocyte proliferation through transcriptional regulation of Ccne1 and blocking JAK2/STAT3 signaling pathway in mice	7
Protein arginine methyltransferase 1, a major regulator of biological processes	7
Neurodevelopmental functions and activities of the KAT3 class of lysine acetyltransferases	7
Lactoferrin efficacy in treating hyperferritinemia in patients suffering from pathologies unrelated to hereditary hemochromatosis	7
SENP1 knockdown potentiates the apoptosis, cell cycle arrest, and reduces cisplatin resistance of diffuse large B cell lymphoma cells via inducing ferroptosis	7
BRD4 promotes the migration and invasion of bladder cancer cells through the Sonic hedgehog signaling pathway and enhances cisplatin resistance	7
Skeletal muscle mitochondrial morphology negatively affected in mice lacking Xin	7
Targeting FHL1 impairs cell proliferation and differentiation of acute myeloid leukemia cells	7
A role for NFIB in SOX2 downregulation and epigenome accessibility changes due to long-term estrogen treatment of breast cancer epithelial cells	7
GCN5 enables HSP12 induction promoting chromatin remodeling, not histone acetylation	6
Note of appreciation	6
Expression of concern: MicroRNA-518-3p suppresses cell proliferation, invasiveness, and migration in colorectal cancer via targeting TRIP4	6
Induction of PDCD4 by albumin in proximal tubule epithelial cells potentiates proteinuria-induced dysfunctional autophagy by negatively targeting Atg5	6
LINE-1: an emerging initiator of cGAS-STING signalling and inflammation that is dysregulated in disease	6
Analysis of financial challenges faced by graduate students in Canada	6
Automatic detection of Cryptosporidium in optical microscopy images using YOLOv5x: a comparative study	6
Adenylate kinases of thermophilesAquifex aeolicusandGeobacillus stearothermophilus: biochemical and kinetic studies	6
E3 ubiquitin ligase HECW1 promotes the metastasis of non-small cell lung cancer cells through mediating the ubiquitination of Smad4	6
SARS-CoV-2 E protein-induced THP-1 pyroptosis is reversed by Ruscogenin	6
Evaluation of drug-free methods for the detection of gene silencing in Saccharomyces cerevisiae	6
Retraction: MiR-1180 promotes cardiomyocyte cell cycle re-entry after injury through the NKIRAS2–NFκB pathway	6
PDGFRβ modulates aerobic glycolysis in osteosarcoma HOS cells via the PI3K/AKT/mTOR/c-Myc pathway	5
HER2 induces cell scattering and invasion through ∆Np63α and E-cadherin	5
Hydrocortisone improves post-resuscitation myocardial dysfunction by inhibiting the NF-κB pathway	5
Antibiofilm activities of lactoferricin-related Trp- and Arg-rich antimicrobial hexapeptides against pathogenic Staphylococcus aureus and Pseudomonas aeruginosa strains	5
PUM1 modulates trophoblast cell proliferation and migration through LRP6	5
Predicting human RNA quadruplex helicases through comparative sequence approaches and helicase mRNA interactome analyses	5
Emerging regulatory challenges of next-generation synthetic biology	5
Time to treat the climate and nature crisis as one indivisible global health emergency	5
Perturbation of calcium homeostasis invokes eryptosis-like cell death in enucleated bone marrow stem cells	5
Epidermal growth factor receptor activity upregulates lactate dehydrogenase A expression, lactate dehydrogenase activity, and lactate secretion in cultured IB3-1 cystic fibrosis lung epithelial cells	5
The regulation of m⁶A-related proteins during whole-body freezing of the freeze-tolerant wood frog	5
Decursin ameliorates carbon-tetrachloride-induced liver fibrosis by facilitating ferroptosis of hepatic stellate cells	5
HDAC1 overexpression promoted by METTL3-IGF2BP2 inhibits FGF21 expression in metabolic syndrome-related liver injury	5
The effects of cetuximab and cisplatin anti-cancer drugs on the mechanical properties of the lung cancerous cells using atomic force microscope	5
Novel insights into RNA polymerase II transcription regulation: transcription factors, phase separation, and their roles in cardiovascular diseases	5

LINC00641 contributes to nasopharyngeal carcinoma cell malignancy through FOXD1 upregulation at the post-transcriptional level	5
Low-dose lipopolysaccharide protects nerve cells against spinal cord injury via regulating the PI3K–AKT–Nrf2 signaling pathway	5
Melatonin inhibits vascular endothelial cell pyroptosis by improving mitochondrial function via up-regulation and demethylation of UQCRC1	5
Cell-in-cell-mediated intercellular communication exacerbates the pro-inflammatory progression in asthma	4
Pathophysiological relevance and therapeutic outlook of GPR43 in atherosclerosis	4
Retraction: Wnt5A regulates the expression of ROR2 tyrosine kinase receptor in ovarian cancer cells	4
ChestCovidNet: An Effective DL-based Approach for COVID-19, Lung Opacity, and Pneumonia Detection Using Chest Radiographs Images	4
Prognostic value and oncogenic effect of increased RBM8A expression in colon adenocarcinoma	4
Reflections on antifreeze proteins and their evolution	4
Histone H4 asymmetrically dimethylated at arginine 3 (H4R3me2a), a mark of super-enhancers	4
IL-6 induced enhanced clearance of proANP and ANP by insulin-degrading enzyme in T1DM mice	4
Retraction: GBP1 exerts inhibitory effects on acute viral myocarditis by inhibiting the inflammatory response of macrophages in mice	4
Retraction: Role of the TSLP–DC–OX40L pathway in asthma pathogenesis and airway inflammation in mice	4
Retraction: MicroRNA-24 alleviates isoflurane-induced neurotoxicity in rat hippocampus via attenuation of oxidative stress	4
Decreased NMIIA heavy chain phosphorylation at S1943 promotes mitoxantrone resistance by upregulating BCRP and N-cadherin expression in breast cancer cells	4
Distinct domain organization and diversity of 2′-5′-oligoadenylate synthetases	4
The lncRNA TUG1 promotes cell growth and migration in colorectal cancer via the TUG1–miR-145-5p–TRPC6 pathway	4
GBP1 exerts inhibitory effects on acute viral myocarditis by inhibiting the inflammatory response of macrophages in mice	4
Crosstalk between chromatin, chromosomes, and epigenetics	4
WDR4 promotes colorectal cancer progression by activating the GSK3β/β-catenin pathway	4
Unveiling stem-like traits and chemoresistance mechanisms in ovarian cancer cells through the TGFβ1-PITX2A/B signaling axis	3
Matrix attachment regions enhance transgene expression by manipulating position-dependent effects in stably transfected CHO-K1 cells	3
The journey from bench to bedside—it takes a science village	3
Identification of critical mitochondrial hub gene for facial nerve regeneration	3
Evolution of techniques and tools for replication fork proteome and protein interaction studies	3
Note of appreciation	3
TMCO1 regulates energy metabolism and mitochondrial function of hepatocellular carcinoma cells through TOMM20, affecting the growth of subcutaneous graft tumors and infiltration of CAFs	3
Pristimerin alleviates cigarette smoke-induced inflammation in chronic obstructive pulmonary disease via inhibiting NF-κB pathway	3
The G protein-coupled receptor GPRC5A—a phorbol ester and retinoic acid-induced orphan receptor with roles in cancer, inflammation, and immunity	3
MiR-494-3p alleviates acute lung injury through regulating NLRP3 activation by targeting CMPK2	3
Optimized total RNA isolation from bovine sperm with enhanced sperm head lysis	3
PCDH7 knockdown potentiates colon cancer cells to chemotherapy via inducing ferroptosis and changes in autophagy through restraining MEK1/2/ERK/c-Fos axis	3
High concentrations of fructose cause brain damage in mice	3
Epidermal melanocytes metabolize extracellular nucleotides by purinergic enzymes	3
Bone marrow granulocytes downregulate IL-1β and TNF production and the microbicidal activity of inflammatory macrophages	3
MTHFD2 suppresses glioblastoma progression via the inhibition of ERK1/2 phosphorylation	3
Note of appreciation	3
Mitochondrial DNA methyltransferases and their regulation under freezing and dehydration stresses in the freeze-tolerant wood frog, Rana sylvatica	3
Protamines and the sperm nuclear basic proteins Pandora’s Box of insects	3
Lipid-induced alteration in retinoic acid signaling leads to mitochondrial dysfunction in HepG2 and Huh7 cells	3
RNF38 inhibits osteosarcoma cell proliferation by binding to CRY1	3
Mitogen- and stress-activated protein kinase (MSK1/2) regulated gene expression in normal and disease states	2
ERCC6 plays a promoting role in the progression of non-small cell lung cancer	2
Attenuation of Hg(II)-induced cellular and DNA damage in human blood cells by uric acid	2
Blockade of anti-dsDNA ameliorates systemic lupus erythematosus in MRL/Faslpr mice through ameliorating inflammation via the PKCδ–NLRC4 axis	2
GCN5 regulates ZBTB16 through acetylation, mediates osteogenic differentiation, and affects orthodontic tooth movement	2
Mechanism of myocardial fibrosis regulation by IGF-1R in atrial fibrillation through the PI3K/Akt/FoxO3a pathway	2
Correction: Ultrasound-stimulated microbubbles contributes to radiotherapy in esophageal carcinoma	2
Bovine lactoferrin increases the poly(I:C)-induced antiviral response in vitro	2
Curcumin attenuates intracerebral hemorrhage-induced neuronal apoptosis and neuroinflammation by suppressing JAK1/STAT1 pathway	2
VEGF-mediated angiogenesis in retinopathy of prematurity is co-regulated by miR-17-5p and miR-20a-5p	2
Yeast profilin mutants inhibit classical nuclear import and alter the balance between actin and tubulin levels	2
Purification and characterization of inorganic pyrophosphatase for in vitro RNA transcription	2
Knockdown of E-cadherin induces cancer stem-cell-like phenotype and drug resistance in cervical cancer cells	2
Granulocyte pro-myeloperoxidase is redundantly processed by proprotein convertase furin and PC7 in HL-60 cells	2
Retraction: The mechanism behind BAF60c in myocardial metabolism in rats with heart failure is through the PGC1α-PPARα-mTOR signaling pathway	2
Effects of aldo-keto reductase family 1 member A on osteoblast differentiation associated with lactate production in MC3T3-E1 preosteoblastic cells	2
LncRNA MSC-AS1 facilitates lung adenocarcinoma through sponging miR-33b-5p to up-regulate GPAM	2
TFAP2A inhibits microRNA-126 expression at the transcriptional level and aggravates ischemic neuronal injury	2
E2F8 facilitates malignant phenotypes of muscle-invasive bladder cancer via increasing MCM7 expression	2
Long non-coding RNA AWPPH enhances malignant phenotypes in nasopharyngeal carcinoma via silencing PTEN through interacting with LSD1 and EZH2	2