OOIR: Observatory of International Research

Papers

(The TQCC of Biochemistry and Cell Biology is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)

Article	Citations
Active vitamin D activates chondrocyte autophagy to reduce osteoarthritis via mediating the AMPK–mTOR signaling pathway	44
PLOD2 promotes aerobic glycolysis and cell progression in colorectal cancer by upregulating HK2	30
Antiviral effects of bovine lactoferrin on human norovirus	30
LncRNA H19 promotes inflammatory response induced by cerebral ischemia–reperfusion injury through regulating the miR-138-5p–p65 axis	24
Lactoferrin, a versatile natural antimicrobial glycoprotein that modulates the host’s innate immunity	23
Circ_KATNAL1 regulates prostate cancer cell growth and invasiveness through the miR-145-3p/WISP1 pathway	23
The N-glycans of lactoferrin: more than just a sweet decoration	23
LncRNA MALAT1 regulates diabetic cardiac fibroblasts through the Hippo–YAP signaling pathway	23
Protective effect of hydralazine on a cellular model of Parkinson’s disease: a possible role of hypoxia-inducible factor (HIF)-1α	22
Biological activities of commercial bovine lactoferrin sources	22
Reversal of P-glycoprotein-mediated multidrug resistance by novel curcumin analogues in paclitaxel-resistant human breast cancer cells	19
MiR-27b-3p suppresses glioma development via targeting YAP1	19
The lncRNA TUG1 promotes cell growth and migration in colorectal cancer via the TUG1–miR-145-5p–TRPC6 pathway	19
MiR-539 inhibits the malignant behavior of breast cancer cells by targeting SP1	18
Antibiofilm activity of lactoferrin-derived synthetic peptides against Pseudomonas aeruginosa PAO1	17
Resveratrol upregulates miR-455-5p to antagonize cisplatin ototoxicity via modulating the PTEN–PI3K–AKT axis	17
Lactoferrin and oral pathologies: a therapeutic treatment	17
Alloimperatorin activates apoptosis, ferroptosis, and oxeiptosis to inhibit the growth and invasion of breast cancer cells in vitro	16
LncRNA MSC-AS1 facilitates lung adenocarcinoma through sponging miR-33b-5p to up-regulate GPAM	16
New insights into the systemic effects of oral lactoferrin: transcriptome profiling	16
Saikosaponin-d protects against liver fibrosis by regulating the estrogen receptor-β/NLRP3 inflammasome pathway	16
Long noncoding RNA KCNQ1OT1 is correlated with human breast cancer cell development through inverse regulation of hsa-miR-107	16
lncRNA CTBP1-AS2 promotes proliferation and migration of glioma by modulating miR-370-3p–Wnt7a-mediated epithelial–mesenchymal transition	15
Effects of oral bovine lactoferrin on a mouse model of inflammation associated colon cancer	15
PML isoform expression and DNA break location relative to PML nuclear bodies impacts the efficiency of homologous recombination	15

Role of SIRT2 in regulating the dexamethasone-activated autophagy pathway in skeletal muscle atrophy	14
A prospective on multiple biological activities of lactoferrin contributing to piglet welfare	14
Formononetin protects against concanavalin-A-induced autoimmune hepatitis in mice through its anti-apoptotic and anti-inflammatory properties	14
Lactoferrin receptors in Gram-negative bacteria: an evolutionary perspective	14
Amplified LncRNA PVT1 promotes lung cancer proliferation and metastasis by facilitating VEGFC expression	14
Melatonin inhibits vascular endothelial cell pyroptosis by improving mitochondrial function via up-regulation and demethylation of UQCRC1	13
Isovitexin attenuates tumor growth in human colon cancer cells through the modulation of apoptosis and epithelial-mesenchymal transition via PI3K/Akt/mTOR signaling pathway	13
Comparative effect of bovine buttermilk, whey, and lactoferrin on the innate immunity receptors and oxidative status of intestinal epithelial cells	13
Tetramethylpyrazine ameliorates hepatic fibrosis through autophagy-mediated inflammation	13
LINP1 promotes the progression of cervical cancer by scaffolding EZH2, LSD1, and DNMT1 to inhibit the expression of KLF2 and PRSS8	13
Cardiovascular protective effects of GLP-1: a focus on the MAPK signaling pathway	12
PYGB facilitates cell proliferation and invasiveness in non-small cell lung cancer by activating the Wnt–β-catenin signaling pathway	12
Dose escalation study of bovine lactoferrin in preterm infants: getting the dose right	12
PCDH7 knockdown potentiates colon cancer cells to chemotherapy via inducing ferroptosis and changes in autophagy through restraining MEK1/2/ERK/c-Fos axis	12
Inhibition of long noncoding RNA MALAT1 suppresses high glucose-induced apoptosis and inflammation in human umbilical vein endothelial cells by suppressing the NF-κB signaling pathway	11
E3 ubiquitin ligase HECW1 promotes the metastasis of non-small cell lung cancer cells through mediating the ubiquitination of Smad4	11
hCINAP is potentially a direct target gene of HIF-1 and is required for hypoxia-induced EMT and apoptosis in cervical cancer cells	11
Exogenous ubiquitin attenuates hypoxia/reoxygenation-induced cardiac myocyte apoptosis via the involvement of CXCR4 and modulation of mitochondrial homeostasis	11
MiR-138-5p knockdown promotes osteogenic differentiation through FOXC1 up-regulation in human bone mesenchymal stem cells	10
Long non-coding RNA DSCAM-AS1 upregulates USP47 expression through sponging miR-101-3p to accelerate osteosarcoma progression	10
Curcumin attenuates intracerebral hemorrhage-induced neuronal apoptosis and neuroinflammation by suppressing JAK1/STAT1 pathway	10
Homogeneity and heterogeneity of biological characteristics in mesenchymal stem cells from human umbilical cords and exfoliated deciduous teeth	10
Astragaloside IV enhanced carboplatin sensitivity in prostate cancer by suppressing AKT/NF-κB signaling pathway	10
PDGFRβ modulates aerobic glycolysis in osteosarcoma HOS cells via the PI3K/AKT/mTOR/c-Myc pathway	10
CLEC5A knockdown protects against cardiac dysfunction after myocardial infarction by suppressing macrophage polarization, NLRP3 inflammasome activation, and pyroptosis	10
LncRNA Gm4419 induces cell apoptosis in hepatic ischemia–reperfusion injury via regulating the miR-455–SOX6 axis	10
DUSP4 inhibits autophagic cell death in PTC by inhibiting JNK–BCL2–Beclin1 signaling	9
Decursin ameliorates carbon-tetrachloride-induced liver fibrosis by facilitating ferroptosis of hepatic stellate cells	9
Nisin induces apoptosis in cervical cancer cells via reactive oxygen species generation and mitochondrial membrane potential changes	9
Lactoferrin and hematoma detoxification after intracerebral hemorrhage	9
Artesunate inhibits proliferation, migration, and invasion of thyroid cancer cells by regulating the PI3K/AKT/FKHR pathway	9
Bovine lactoferrin and lactoferrin peptides affect endometrial and cervical cancer cell lines	9
TGF-β1-containing exosomes from cardiac microvascular endothelial cells mediate cardiac fibroblast activation under high glucose conditions	8
ELFIN, the United Kingdom preterm lactoferrin trial: interpretation and future questions	8
Thidiazuron suppresses breast cancer via targeting miR-132 and dysregulation of the PI3K–Akt signaling pathway mediated by the miR-202-5p–PTEN axis	8
VEGF-mediated angiogenesis in retinopathy of prematurity is co-regulated by miR-17-5p and miR-20a-5p	8
Paeonol reduces IL-β production by inhibiting the activation of nucleotide oligomerization domain-like receptor protein-3 inflammasome and nuclear factor-κB in macrophages	8
SOAT1 enhances lung cancer invasiveness by stimulating AKT-mediated mitochondrial fragmentation	8
Knockdown of E-cadherin induces cancer stem-cell-like phenotype and drug resistance in cervical cancer cells	8
Circ_BMP2K enhances the regulatory effects of miR-455-3p on its target gene SUMO1 and thereby inhibits the activation of cardiac fibroblasts	8
Glycerol kinase enhances hepatic lipid metabolism by repressing nuclear receptor subfamily 4 group A1 in the nucleus	7
Silencing LINC00511 inhibits cell proliferation, migration, and epithelial–mesenchymal transition via the PTEN–AKT–FOXO1 signaling pathway in lung cancer	7
MicroRNA-760-mediated low expression of DUSP1 impedes the protective effect of NaHS on myocardial ischemia–reperfusion injury	7
MiR-1180 promotes cardiomyocyte cell cycle re-entry after injury through the NKIRAS2–NFκB pathway	7
LncRNA IDH1-AS1 suppresses cell proliferation and tumor growth in glioma	7
Chondroitin polymerizing factor (CHPF) contributes to malignant proliferation and migration of hepatocellular carcinoma cells	7
SET8, a novel regulator to ameliorate vascular calcification via activating PI3K/Akt mediated anti-apoptotic effects	7
MiR-494-3p alleviates acute lung injury through regulating NLRP3 activation by targeting CMPK2	7
Binding of lactoferrin to the surface of low-density lipoproteins modified by myeloperoxidase prevents intracellular cholesterol accumulation by human blood monocytes	7
S-allylcysteine inhibits chondrocyte inflammation to reduce human osteoarthritis via targeting RAGE, TLR4, JNK, and Nrf2 signaling: comparison with colchicine	7

LFchimera: a synthetic mimic of the two antimicrobial domains of bovine lactoferrin	7
Adipocyte factor CTRP6 inhibits homocysteine-induced proliferation, migration, and dedifferentiation of vascular smooth muscle cells through PPARγ/NLRP3	7
Low-dose lipopolysaccharide protects nerve cells against spinal cord injury via regulating the PI3K–AKT–Nrf2 signaling pathway	7
Interaction between the guanylate kinase domain of PSD-95 and the proline-rich region and microtubule binding repeats 2 and 3 of tau	7