OOIR: Observatory of International Research

Papers

(The median citation count of International Reviews of Immunology is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Combinatorial approaches to effective therapy in glioblastoma (GBM): Current status and what the future holds	96
Regulatory Effects of Clock and Bmal1 on Circadian Rhythmic TLR Expression	82
How metabolism and metabolites shape immunity during disease	49
Vaccine design and development: Exploring the interface with computational biology and AI	45
Combining the past and present to advance immuno-radiotherapy of cancer	34
Transforming growth factor-β in tumor microenvironment: Understanding its impact on monocytes and macrophages for its targeting	32
The ubiquitous role of spleen tyrosine kinase (Syk) in gut diseases: From mucosal immunity to targeted therapy	32
Can interventions targeting MDSCs improve the outcome of vaccination in vulnerable populations?	26
Dysregulated metabolism: A friend-to-foe skewer of macrophages	20
The NLRP3 inflammasome: Mechanisms of activation, regulation, and role in diseases	18
Insights into the modulation of the interferon response and NAD⁺in the context of COVID-19	18
Role of thymus in health and disease	17
Cholesterol: A friend to viruses	16
The role of γδ T cells in the interaction between commensal and pathogenic bacteria in the intestinal mucosa	16
Breaking the graft-versus-host-disease barrier: Mesenchymal stromal/stem cells as precision healers	15
Research progress on the role and mechanism of action of exosomes in autoimmune thyroid disease	14
HCMV miR-UL70-3p downregulates the rapamycin-induced autophagy by targeting the autophagy-related protein 9A (ATG9A)	14
Chemokines: A key driver for inflammation in protozoan infection	13
Low-dose IL-2 therapy in autoimmune diseases: An update review	12
Disparities in positive results and dissemination of randomized controlled trials in immuno-oncology	12
RNA methylation: A potential therapeutic target in autoimmune disease	12
Cancer and immunity: who is shaping whom?	10
Role of PE family of proteins in mycobacterial virulence: Potential on anti-TB vaccine and drug design	9
Boosting immune responses in lung tumor immune microenvironment: A comprehensive review of strategies and adjuvants	9
Extracellular vesicles in obesity and its associated inflammation	9

Immunological processes of enhancers and suppressors of long non-coding RNAs associated with brain tumors and inflammation	9
Neutrophil extracellular trap-associated molecules: a review on their immunophysiological and inflammatory roles	8
Components of specific immunity in host defense	8
COVID-19 and oral diseases: Assessing manifestations of a new pathogen in oral infections	8
Natural and genetically-modified animal models to investigate pulmonary and extrapulmonary manifestations of COVID-19	8
T cell receptor revision and immune repertoire changes in autoimmune diseases	7
Advances and challenges in CAR-T cell-mediated immunotherapy	7
Clinical utility of CAR T cell therapy in brain tumors: Lessons learned from the past, current evidence and the future stakes	6
Re-inventing traditional aluminum-based adjuvants: Insight into a century of advancements	6
The potential targets in immunotherapy of atherosclerosis	6
STATs signaling pathways in dendritic cells: As potential therapeutic targets?	5
Host factors subverted by Mycobacterium tuberculosis: Potential targets for host directed therapy	5
Retraction	5
Diversity of T cells in the skin: Novel insights	5
The molecular landscape of T cell exhaustion in the tumor microenvironment and reinvigoration strategies	5
Immunological and biological dissection of normal and tumoral salivary glands	4
Scaling up and scaling out: Advances and challenges in manufacturing engineered T cell therapies	4
Antibody engineering and its therapeutic applications	4
MDSCs interactions with other immune cells and their role in maternal-fetal tolerance	4
Fatal ReincaRNAtion of VIRUS causing COronaVIrus disease	3
Orchestration of immune response by innate lymphoid cell subtype 2 at various tumor microenvironment, a suitable target for cancer immunotherapy	3
Next generation strategies to recover immunological tolerance in celiac disease	3
The role of sialic acid-binding immunoglobulin-like-lectin-1 (siglec-1) in immunology and infectious disease	3
E3 ubiquitin ligase Smurf1 promotes cardiomyocyte pyroptosis by mediating ubiquitin-dependent degradation of TRIB2 in a rat model of heart failure	3
Exploring the pathways of inflammation and coagulopathy in COVID-19: A narrative tour into a viral rabbit hole	3
Tuberculosis vaccine BCG: the magical effect of the old vaccine in the fight against the COVID-19 pandemic	2
Tapping the immunological imprints to design chimeric SARS-CoV-2 vaccine for elderly population	2
Innate immunity: Trained immunity and innate allorecognition against the allograft	2
Recurrent respiratory papillomatosis: Immunological mechanisms involved in recurrence	2
Role of natural killer and B cell interaction in inducing pathogen specific immune responses	2
Asthma research in mice: An overview of current models and their methodological variability	2
Understanding innate and adaptive responses during radiation combined burn injuries	2
B7-H3-targeted CAR-T cell therapy for solid tumors	2