Journal of Bone and Mineral Research

Papers
(The median citation count of Journal of Bone and Mineral Research is 0. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)
ArticleCitations
Causal Relationship Between Sarcopenia and Fracture: A Two‐Sample Mendelian Randomized Study175
Comparative cardiovascular safety of romosozumab versus bisphosphonates in Japanese patients with osteoporosis: a new-user, active comparator design with instrumental variable analyses54
Preclinical evaluation of the efficacy and safety of adeno-associated virus 8-tissue-nonspecific alkaline phosphatase-D10 in Alpl-/- and AlplPrx1/Prx1 mouse models for the treatment of e52
Probability of achieving bone mineral density treatment goals with denosumab treatment in postmenopausal women with osteoporosis47
Prediction of hip fracture by high-resolution peripheral quantitative computed tomography in older Swedish women43
Brittle, but not boring: a fresh look at osteogenesis imperfecta type V38
Denosumab discontinuation in the clinic: implications of rebound bone turnover and emerging strategies to prevent bone loss and fractures27
Measurements of the Vitamin D Metabolome in the Calgary Vitamin D Study: Relationship of Vitamin D Metabolites to Bone Loss23
An unresolving painful condition following a trivial peripheral fracture19
The Added Value of High‐Resolution Peripheral Quantitative Computed Tomography in Fracture Risk Prediction16
Ambulatory children with spastic cerebral palsy have smaller bone area and deficits in trabecular microarchitecture16
Bmi‐1 Overexpression Improves Sarcopenia Induced by 1,25(OH)2D3 Deficiency and Downregulates GATA4‐Dependent Rela Transcription15
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Transferability of bone phenotyping and fracture risk assessment by μFRAC from first-generation high-resolution peripheral quantitative computed tomography to second-generation scan data12
KDM6B preferentially promotes bone formation over resorption to facilitate postnatal bone mass accrual through CTHRC1-mediated PKCδ/MAPKs signaling11
Journal of Bone and Mineral Research: Volume 36, Number 11, November 202111
Is There a Causal Relationship between Physical Activity and Bone Microarchitecture? A Study of Adult Female Twin Pairs11
Ed Bd, Masthead, Comm List and TOC11
Simultaneous automated ascertainment of prevalent vertebral fracture and abdominal aortic calcification in clinical practice: role in fracture risk assessment11
Ed Bd, Masthead, Comm List and TOC11
Issue Information - Declaration of Helsinki10
Retraction of: CYP4A22 loss-of-function causes a new type of vitamin D–dependent rickets (VDDR1C)10
Risk of Fractures in Thyroid Cancer Patients With Postoperative Hypoparathyroidism: A Nationwide Cohort Study in Korea10
Ed Bd, Masthead, Comm List and TOC10
Proteins and pathways involved in inflammation are longitudinally associated with total body bone mineral density among primarily Hispanic overweight/obese adolescents and young adults10
Quantifying Bone Strength Deficits in Young Adults Born Extremely Preterm or Extremely Low Birth Weight10
Loss-of-function of DDR1 is responsible for a chondrodysplasia with multiple dislocations10
Influence of vitamin D supplementation on bone mineral content, bone turnover markers, and fracture risk in South African schoolchildren: multicenter double-blind randomized placebo-controlled trial (10
Bub1 suppresses inflammatory arthritis–associated bone loss in mice through inhibition of TNFα–mediated osteoclastogenesis9
Association Between Combat‐Related Traumatic Injury and Skeletal Health: Bone Mineral Density Loss Is Localized and Correlates With Altered Loading in Amputees: the Armed Services Trauma Rehabilitatio9
Predicting Imminent Fractures in Patients With a Recent Fracture or Starting Oral Bisphosphonate Therapy: Development and International Validation of Prognostic Models9
Are osteoblasts multiple cell types? A new diversity in skeletal stem cells and their derivatives9
One day at a time: understanding how 24-hr physical activity, sedentary behavior and sleep patterns influence falls and fracture risk9
Association of Sleep Traits and Heel Bone Mineral Density: Observational and Mendelian Randomization Studies9
Epidural steroid injections and fracture incidence among older individuals with radiculopathy9
Direct activation of PI3K in osteoblasts and osteocytes strengthens murine bone through sex-specific actions on cortical surfaces9
Magnesium Ascorbyl Phosphate Promotes Bone Formation Via CaMKII Signaling9
Anabolic Window-Like Phenomenon After Biochemical Remission in Cushing's Syndrome: Does Surge in Bone Turnover Markers Correlate With Improved Bone Mineral Density?9
Correction to “Chronic Systemic Infection of Mice with Leishmania infantum Leads to Increased Bone Mass”9
The lack of EphB3 receptor prevents bone loss in mouse models of osteoporosis8
Romosozumab following denosumab improves lumbar spine bone mineral density and trabecular bone score greater than denosumab continuation in postmenopausal women8
Treating osteoporosis in the oldest old8
Loss of the long form of Plod2 phenocopies contractures of Bruck syndrome—osteogenesis imperfecta8
Family-based whole-exome sequencing implicates a variant in lysyl oxidase like 4 in atypical femur fractures8
Prevention of Hip Fractures: Trade-off between Minor Benefits to Individuals and Large Benefits to the Community8
Leptin receptor (+) stromal cells respond to periodontitis and attenuate alveolar bone repair via CCRL2-mediated Wnt inhibition8
Eiken syndrome with parathyroid hormone resistance due to a novel parathyroid hormone receptor type 1 mutation: clinical features and functional analysis8
Approaching virtual osteoid volume estimation and in-depth tissue characterization in patients with tumor-induced osteomalacia7
Fractures by race and ethnicity in a diverse sample of postmenopausal women: a current evaluation among Hispanic and Asian origin groups7
Load carriage exercise increases calcium absorption and retention in healthy young women7
β-Hydroxybutyrate ameliorates osteoarthritis through activation of the ERBB3 signaling pathway in mice7
Smoking in pregnancy increases offspring fracture risk: yet another reason to encourage smoking cessation7
Why are local epidural glucocorticoid injections associated with fractures? Drug, disease, or both?7
Standardization of bone morphometry and mineral density assessments in zebrafish and other small laboratory fishes using X-ray radiography and micro-computed tomography7
Association of white matter hyperintensities with BMD, incident fractures, and falls in the UK Biobank cohort6
Risk of fracture in patients with myasthenia gravis: a nationwide cohort study in Korea6
Large-scale circulating proteome association study (CPAS) meta-analysis identifies circulating proteins and pathways predicting incident hip fractures6
Response to the editor of JBMR regarding the letter related to “Opportunistic screening with CT: comparison of phantomless BMD calibration methods”6
Pharmacogenetic and microRNA mechanisms of beta blocker use on bone6
The American Society for Bone and Mineral Research Task Force on clinical algorithms for fracture risk report6
Genomic structural variations link multiple genes to bone mineral density in a multi-ethnic cohort study: Louisiana osteoporosis study6
Response to the letter to the editor regarding “The American Society for Bone and Mineral Research Task Force on clinical algorithms for fracture risk report”6
Bone microarchitecture and strength in men and women with PLS3 gene variants assessed with HR-pQCT6
Hypophosphatemic rickets and short stature6
Deciphering the spatial distribution of Gli1-lineage cells in dental, oral, and craniofacial regions5
Effect of BMI-Discordant Abdominal Tissue Thickness on Fracture Probability: A Registry-Based Study5
Macrophages and Bone Remodeling5
The challenges of investigating causes and recovery from osteoporosis associated with pregnancy and lactation5
Causal inference in health and disease: a review of the principles and applications of Mendelian randomization5
Opportunistic Screening With CT: Comparison of Phantomless BMD Calibration Methods5
The chromatin remodeling factor Arid1a cooperates with Jun/Fos to promote osteoclastogenesis by epigenetically upregulating Siglec15 expression5
Bmpr1aa modulates the severity of the skeletal phenotype in an fkbp10-deficient Bruck syndrome zebrafish model5
Time-lapse HR-pQCT reliably assesses and monitors local bone turnover in patients with chronic kidney disease5
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Association of vertebral fractures with worsening degenerative changes of the spine: a longitudinal study4
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Issue Information ‐ Declaration of Helsinki4
Cannabidiol and Cannabigerol, Nonpsychotropic Cannabinoids, as Analgesics that Effectively Manage Bone Fracture Pain and Promote Healing in Mice4
Assessment of causal association between the socio-economic status and osteoporosis and fractures: a bidirectional Mendelian randomization study in European population4
Rosa Maria Rodrigues Pereira (1958–2022)4
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Depletion of marrow adipo-CAR cells in mice enhances bone formation by activating BMPR in pre-osteoblasts4
Heme metabolism mediates RANKL-induced osteoclastogenesis via mitochondrial oxidative phosphorylation3
Journal of Bone and Mineral Research: Volume 38, Number 9, September 20233
Response to Pan et al.3
Nonalcoholic Fatty Liver Disease Is Associated With Decreased Bone Mineral Density in Adults: A Systematic Review and Meta‐Analysis3
Ed Bd, Masthead, Comm List and TOC3
Ablation of Proliferating Osteoblast Lineage Cells After Fracture Leads to Atrophic Nonunion in a Mouse Model3
Ed Bd, Masthead, Comm List and TOC3
Retracted: CYP4A22 loss-of-function causes a new type of vitamin D–dependent rickets (VDDR1C)3
Bone health in women living with HIV in Sub-Saharan Africa: antiretroviral therapy, lactation, and menopause3
Reduced GS Domain Serine/Threonine Requirements of Fibrodysplasia Ossificans Progressiva Mutant Type I BMP Receptor ACVR1 in the Zebrafish3
Journal of Bone and Mineral Research: Volume 38, Number 10, October 20233
Low miR‐182‐5p Expressing Extracellular Vesicles Derived From Human Bone Marrow Stromal Cells of Subjects With Steroid‐Induced Osteonecrosis of the Femoral Head Aggravate Disease Progressio3
Journal of Bone and Mineral Research: Volume 38, Number 8, August 20233
Romosozumab Use and Cardiovascular Events3
cGAS-STING Aggravates Cartilage Degradation by Promoting Glycolysis in TMJOA3
Hdac3-deficiency increases senescence-associated distention of satellite DNA and telomere-associated foci in osteoprogenitor cells3
Response to Letter to the Editor regarding “Increased advanced glycation endproducts, stiffness, and hardness in iliac crest bone from postmenopausal women with type 2 diabetes mellitus on insulin”3
Interactions Between HR‐pQCT Bone Density and D3Cr Muscle Mass (or HR‐pQCT Bone Structure and HR‐pQCT Muscle Density) in Predicting Fractures: Th3
Therapeutic Potential of Cannabidiol and Cannabigerol in Fracture Healing3
Journal of Bone and Mineral Research: Volume 38, Number 11, November 20233
Single‐Cell Transcriptomic Atlas of Parathyroid Adenoma and Parathyroid Carcinoma3
Professor Philippe Crine: a hero for children with hypophosphatasia3
The potential of the proteome to predict fracture3
Kangfuxin Accelerates Extraction Socket Healing by Promoting Angiogenesis Via Upregulation of CCL2 in Stem Cells3
Correction to: Effects of Supplemental Vitamin D on Bone Health Outcomes in Women and Men in the VITamin D and OmegA-3 TriaL (VITAL)3
Retraction Statement: Release of CXCL12 From Apoptotic Skeletal Cells Contributes to Bone Growth Defects Following Dexamethasone Therapy in Rats3
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Bacterial Lipopolysaccharides Exacerbate Neurogenic Heterotopic Ossification Development2
VEGF Secretion Drives Bone Formation in Classical MAP2K1+ Melorheostosis2
No Effect of NSAID Use on Efficacy of Zoledronate: A Post Hoc Analysis of a Randomized Trial in Osteopenic Older Women2
SNX10 regulates osteoclastogenic cell fusion and osteoclast size in mice2
FRAX predicts cardiovascular risk in women undergoing osteoporosis screening: the Manitoba bone mineral density registry2
Rapid bone microarchitecture decline in older men with high bone turnover—the prospective STRAMBO study2
Grade 1 vertebral fractures, bone mineral density, and the risk of fractures2
Pre-treatment bone mineral density and the benefit of pharmacologic treatment on fracture risk and BMD change: analysis from the FNIH-ASBMR SABRE project2
Osteoclast-derived coupling factors: origins and state-of-play Louis V Avioli lecture, ASBMR 20232
Modification of bone architecture following sleeve gastrectomy: a five-year follow-up2
Occlusal force orchestrates alveolar bone homeostasis via Piezo1 in female mice2
Hypoparathyroidism: changes in brain structure, cognitive impairment, and reduced quality of life2
Genome-wide association study of osteoporosis identifies genetic risk and interactions with Dietary Approaches to Stop Hypertension diet and sugar-sweetened beverages in a Hispanic cohort of older adu2
Editorial: the role of vitamin D metabolites in the evaluation of bone health: are they physiologically relevant?2
Microbiome–induced increases and decreases in bone matrix strength can be initiated after skeletal maturity2
A novel oral hPTH(1-34) unveils the promise of modeling-based anabolism with no increase in bone remodeling2
Bariatric surgery increases the rate of major fracture: self-controlled case series study in UK Clinical Practice Research Datalink2
Bone biopsy for the diagnosis of osteomalacia. Can we avoid it?2
Impact of the SIK3 pathway inhibition on osteoclast differentiation via oxidative phosphorylation2
Setrusumab for the treatment of osteogenesis imperfecta: 12-month results from the phase 2b asteroid study2
Epiregulin ameliorates ovariectomy-induced bone loss through orchestrating the differentiation of osteoblasts and osteoclasts2
A systematic review and meta-analysis of the effects of probiotics on bone outcomes in rodent models2
Bone remodeling and responsiveness to mechanical stimuli in individuals with type 1 diabetes mellitus2
Identification ofkinesin family member (KIF22)homozygous variants in spondyloepimetaphyseal dysplasia with joint laxity, lepdodactylic type and demonstration of proteoglycan biosynthesis impair2
Influence of age on the efficacy of pharmacologic treatments on fracture risk reduction and increases in BMD: RCT results from the FNIH-ASBMR-SABRE project2
Fracture risk prediction in postmenopausal women with traditional and machine learning models in a nationwide, prospective cohort study in Switzerland with validation in the UK Biobank2
Increased BMSi Association With Risk of Incident Osteoporotic Fractures2
Neuronal regulation of bone and tendon injury repair: a focused review2
Breathing Easy for Better Bones: The Undervalued Role of Air Quality in Bone Health2
Thrombopoietic agents enhance bone healing in mice, rats, and pigs2
Testosterone Restores Body Composition, Bone Mass, and Bone Strength Following Early Puberty Suppression in a Mouse Model Mimicking the Clinical Strategy in Trans Boys2
Efficacy and Safety of Transdermal Abaloparatide in Postmenopausal Women with Osteoporosis: A Randomized Study2
Improving the value and interpretation of observational studies comparing treatment effects of osteoporosis medications depends on standardized reporting of methods2
Temporal patterns of osteoclast formation and activity following withdrawal of RANKL inhibition2
Assessing the effects of immune checkpoint inhibitors on bone utilizing machine learning–assisted opportunistic quantitative computed tomography2
Patella fractures are associated with bone fragility – a retrospective study2
Male–female spatio-temporal differences of age-related bone changes show faster bone deterioration in older women at femoral regions associated with incident hip fracture2
RANKL signaling drives skeletal muscle into the oxidative profile2
Acetyltransferases CBP/p300 Control Transcriptional Switch of β-Catenin and Stat1 Promoting Osteoblast Differentiation2
Sedentary behavior does not predict low BMD nor fracture—population-based Canadian Multicentre Osteoporosis Study2
Shadow on the mind: hypoparathyroidism’s impact on brain and well-being2
Deapi-platycodin D3 attenuates osteoarthritis development via suppression of PTP1B2
Bone Marrow Adiposity Alterations in Type 2 Diabetes Are Sex-Specific and Associated with Serum Lipid Levels1
Distinguishing risk of curve progression in adolescent idiopathic scoliosis with bone microarchitecture phenotyping: a 6-year longitudinal study1
Vertebral compression fractures at abdominal CT: underdiagnosis, undertreatment, and evaluation of an AI algorithm1
Inactivation of spermine synthase in mice causes osteopenia due to reduced osteoblast activity1
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The relationship between treatment-related changes in total hip BMD measured after 12, 18, and 24 mo and fracture risk reduction in osteoporosis clinical trials: the FNIH-ASBMR-SABRE project1
Dentoalveolar Alterations in an Adenine‐Induced Chronic Kidney Disease Mouse Model1
Issue Information ‐ Declaration of Helsinki1
The role of vitamin D metabolism in regulating bone turnover in adolescents with perinatally-acquired HIV in Southern Africa: a cross-sectional study in Zimbabwe and Zambia1
Possible role of bone turnover markers in the diagnosis of adult hypophosphatasia1
Development and reporting of artificial intelligence in osteoporosis management1
Defining the key clinician skills and attributes for competency managing patients with osteoporosis and fragility fractures1
Causal relationship between sarcopenia and fracture: a two-sample Mendelian randomized study1
Skeletal effects of adjuvant zoledronic acid and its cessation in women with early-stage breast cancer1
Low–dose infigratinib increases bone growth and corrects growth plate abnormalities in an achondroplasia mouse model1
Performance of Fracture Risk Assessment Tools by Race and Ethnicity: A Systematic Review for the ASBMR Task Force on Clinical Algorithms for Fracture Risk1
The hypoxia signature across skeletal progenitor cells1
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Trial emulation to improve fracture prevention treatment in men: editorial on ASBMR-240301741
Global Epidemiology of Hip Fractures: Secular Trends in Incidence Rate, Post‐Fracture Treatment, and All‐Cause Mortality1
The comparative effect of teriparatide and denosumab on activins, follistatins, and inhibins in women with postmenopausal osteoporosis1
Higher serum free thyroxine levels are associated with increased risk of hip fractures in older men1
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Comparative effectiveness and safety outcomes between denosumab and bisphosphonate in South Korea1
Nephrocalcinosis and kidney function in children and adults with X-linked hypophosphatemia: baseline results from a large longitudinal study1
Changes in peripheral quantitative computed tomography measured bone density, size, and strength in Zimbabwean children with and without HIV over one year: a cohort study1
A skeleton in a huff: insights in etiologies of osteosclerosis1
Twelve Months of Denosumab and/or Alendronate Is Associated With Improved Bone Fatigue Life, Microarchitecture, and Density in Ovariectomized Cynomolgus Monkeys1
Single-cell RNA sequencing reveals that an imbalance in monocyte subsets rather than changes in gene expression patterns is a feature of postmenopausal osteoporosis1
Romosozumab improves microarchitecture as assessed by tissue thickness–adjusted trabecular bone score in postmenopausal women with osteoporosis1
Ed Bd, Masthead, Comm List and TOC1
Microvascular disease and early diabetes onset are associated with deficits in femoral neck bone density and structure among older adults with longstanding type 1 diabetes1
RNA-based bone histomorphometry: method and its application to explaining postpubertal bone gain in a G610C mouse model of osteogenesis imperfecta1
Loss of Sprouty Produces a Ciliopathic Skeletal Phenotype in Mice Through Upregulation of Hedgehog Signaling1
Prolonged bone health benefits for breast cancer patients following adjuvant bisphosphonate therapy: the BoHFAB study1
Active Vitamin D Use and Fractures in Hemodialysis Patients: Results from the International DOPPS1
The quantification of bone mineral density using photon counting computed tomography and its implications for detecting bone remodeling1
miR‐196b‐5p Regulates Osteoblast and Osteoclast Differentiation and Bone Homeostasis by Targeting SEMA3A1
Correction to: Calcifediol is superior to cholecalciferol in improving vitamin D status in postmenopausal women: a randomized trial1
Risk factors for hip and vertebral fractures in chronic kidney disease: the CRIC study1
Association of Bone Mineral Density and Bone Turnover Markers with the Risk of Diabetes: Hong Kong Osteoporosis Study and Mendelian Randomization1
Reversible Effects of Puberty Suppression on Bone Strength, Mass, and Body Composition in Adolescent Mice After Testosterone Therapy1
Calorie restriction in mice impairs cortical but not trabecular peak bone mass by suppressing bone remodeling1
Gene-based association analysis of a large patient cohort provides insights into genetics of atypical femur fractures1
One-carbon metabolism supports S-adenosylmethionine and m6A methylation to control the osteogenesis of bone marrow stem cells and bone formation1
Identification of GNAS Variants in Circulating Cell‐Free DNA from Patients with Fibrous Dysplasia/McCune Albright Syndrome1
Decline in muscle strength and physical function after fracture in men – the prospective STRAMBO study1
Sequential Therapy With Recombinant Human IGF-1 Followed by Risedronate Increases Spine Bone Mineral Density in Women With Anorexia Nervosa: A Randomized, Placebo-Controlled Trial1
Fractures in women with type 2 diabetes are associated with marked deficits in cortical parameters and trabecular plates1
Evaluating the comparability of osteoporosis treatments using propensity score and negative control outcome methods in UK and Denmark electronic health record databases1
Vitamin D Metabolites Are Associated With Musculoskeletal Injury in Young Adults: A Prospective Cohort Study1
Oral daily PTH(1-34) tablets (EB613) in postmenopausal women with low BMD or osteoporosis: a randomized, placebo-controlled, 6-month, phase 2 study1
Deletion of the auxiliary α2δ1 voltage sensitive calcium channel subunit in osteocytes and late-stage osteoblasts impairs femur strength and load-induced bone formation in male mice1
Efficacy and Toxicity of Calcitonin Treatment in Children with Cherubism: A Single-Center Cohort Study1
Genetic predisposition to bone mineral density and their health conditions in East Asians1
Evaluation of the Effect of Sodium-Glucose Cotransporter 2 Inhibition on Fracture Risk: Evidence From Mendelian Randomization and Genetic Association Study1
In Memoriam: Charles Chan1
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GSTT1 as a Predictive Marker and Enhancer for Osteogenic Potential of Human Adipose-Derived Stromal/Stem Cells1
Reduction of New Heterotopic Ossification (HO) in the Open‐Label, Phase 3 MOVE Trial of Palovarotene for Fibrodysplasia Ossificans Progressiva (FOP)1
Early and multiple doses of zoledronate mitigates rebound bone loss following withdrawal of receptor activator of nuclear factor kappa-B ligand inhibition0
Osteoporosis treatment prevents hip fracture similarly in both sexes: the FOCUS observational study0
Sphingosine-1-phosphate promotes osteogenesis by stimulating osteoblast growth and neovascularization in a vascular endothelial growth factor–dependent manner0
The G protein-coupled receptor ADGRG6 maintains mouse growth plate homeostasis through IHH signaling0
Prevalence of incomplete atypical femoral fractures using single energy absorptiometry after long-term anti-resorptive therapy0
Ed Bd, Masthead, Comm List and TOC0
JBMR Reviewer List 20230
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Synovium and infrapatellar fat pad share common mesenchymal progenitors and undergo coordinated changes in osteoarthritis0
Association of Preterm Birth and Low Birthweight with Bone Fractures during Childhood0
2024 Annual Meeting of the American Society for Bone and Mineral Research, September 27-30, 20240
Individuals with heterogenous trabecular bone texture by clinical magnetic resonance imaging have lower bone strength and stiffness by quantitative computed tomography-based finite element analysis0
The Multifarious Functions of Leukotrienes in Bone Metabolism0
Correction to “Durability and Delayed Treatment Effects of Zoledronic Acid on Bone Loss after Spinal Cord Injury: A Randomized, Controlled Trial”0
TMCO3, a Putative K+:Proton Antiporter at the Golgi Apparatus, Is Important for Longitudinal Growth in Mice and Humans0
Issue Information ‐ Declaration of Helsinki0
Biochemical Markers of Calcium and Bone Metabolism during and after Lactation in Ugandan Women with HIV on Universal Maternal Antiretroviral Therapy0
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A delicate balance: the challenges of hypoparathyroidism0
Periprosthetic Joint Infections of the Knee Lastingly Impact the Bone Homeostasis0
Preterm birth and risk of bone fractures during childhood and early adulthood0
Diagnosis and therapeutic decisions of osteoporosis in chronic kidney disease0
Positive Effect of Parathyroidectomy Compared to Observation on BMD in a Randomized Controlled Trial of Mild Primary Hyperparathyroidism0
Calcium balance: considerations for the bone response to exercise0
Journal of Bone and Mineral Research: Volume 38, Number 3, March 20230
Issue Information - Declaration of Helsinki0
Correction to “Denosumab for Prevention of Acute Onset Immobilization‐Induced Alterations of Bone Turnover: A Randomized Controlled Trial”0
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Ectopic Calcification and Hypophosphatemic Rickets: Natural History of ENPP1 and ABCC6 Deficiencies0
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