Biotechnology and Applied Biochemistry

Papers
(The TQCC of Biotechnology and Applied Biochemistry is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)
ArticleCitations
Activation of GPR55 alleviates neuropathic pain and chronic inflammation141
Enzyme Treated Sapota Seed Dietary Fibre Is a Novel Prebiotic Feed Additive: In Vitro Studies48
Enzymatic Hydrolysis of Soybean Meals in Deep Eutectic Solvents and Ionic Liquids: Experimental and Molecular Insights43
Gold nanourchin on multiple‐point dielectrode for glucose biosensing by current‐potential measurement39
Design and simulation of a novel integrated microfluidic chip for cell isolation and culture35
A GH42 β‐galactosidase from Bifidobacterium thermophilum: Biochemical characterization and synthesis of galactosyl glycerol by reverse hydrolysis29
Annexin A1 protects periodontal ligament cells against lipopolysaccharide‐induced inflammatory response and cellular senescence: An implication in periodontitis28
The effect of thyme essential oil and endothelial progenitor stem cells on lipopolysaccharide‐induced sepsis in C57BL/6 mice28
Efficient coexpression of recombinant human fusion collagen with prolyl 4‐hydroxylase from Bacillus anthracis in Escherichia coli27
Different experimental approaches for Fourier‐transform infrared spectroscopy applications in biology and biotechnology: A selected choice of representative results26
Sulfonamide derivatives with benzothiazole scaffold: Synthesis and carbonic anhydrase I–II inhibition properties26
Fabrication of Bioconjugates Clacked Chitosan‐Coated SN‐38 Liposomal Nanoparticles: Improved Precise Chemotherapy Efficacy in Lung Cancer Cells and Its Apoptosis25
Aquaporin 9: Exacerbation of Vulnerable Carotid Plaque Formation24
Issue Information23
Isoindole‐1,3‐Dione Sulfonamides as Potent Inhibitors of Glucosidase, Aldose Reductase, and Tyrosinase: A Molecular Docking and Enzyme Inhibition Study22
Issue Information22
The anti‐spermatogenic activity of nanoliposomes loaded with Heracleum persicum phenolic compounds in Balb/C mice21
Synthesis and characterization of N‐rich fluorescent bio‐dots as a reporter in the design of dual‐labeled FRET probe for TaqMan PCR: A feasibility study20
Regulation of hsa_circ_0112136 by m6A demethylase FTO can enhance the malignancy of gastric cancer via the regulation of the PI3K/AKT/mTOR pathway18
Hyposalivation in patients with psoriasis: Association with severity, inflammatory, and anti‐inflammatory cytokine biomarkers of the disease18
Alginate‐derived carbon dots for “turn off–on” anti‐neoplastic 5‐fluorouracil sensing in biological samples18
Preparation of silver nanoparticles by Osbeckia stellata aqueous extract via green synthesis approach: Characterization and assessment of their antioxidant, antidiabetic, cytotoxicity, and anti17
Network Pharmacology and Experimental Evaluation of Lonicera japonica Flos in Rheumatoid Arthritis17
Protective Effect and Gut Microbiota Modulation of Grifola frondosa Antioxidant Peptides in Sodium Dextran Sulfate‐Induced Ulcerative Colitis Mice16
Biosynthesis of Microbial Pigment‐Mediated Nanoparticles and Its Biomedical Applications16
Zerumbone‐induced reactive oxygen species‐mediated oxidative stress re‐sensitizes breast cancer cells to paclitaxel16
Thrombolytic and anticoagulant efficiencies of purified fibrinolytic enzyme produced from Cochliobolus hawaiiensis under solid‐state fermentation16
Isolation and structural characterization of exopolysaccharide from the Cordyceps cicadae and the immunomodulatory activity on RAW264.7 cells15
Cloning and expression analysis of HY5 transcription factor gene of safflower in response to light signal15
Reconnoitring the antioxidant and antibacterial potential of different fruits after tannin acyl hydrolase mediated biotransformation15
Antimicrobial effect of pimozide by targeting ROS‐mediated killing in Staphylococcus aureus14
Isolation, cloning, and functional analysis of a putative constitutive promoter of E3 ubiquitin‐protein ligase RF4 from Coleus amboinicus Lour14
Antidiabetic Potential of Synthesized Ferrocenylmethylaniline Derivatives: Insights From In Vitro Studies, Molecular Docking, ADMET, DFT Calculations, and Molecular Dynamics Simulation14
Abnormal expression of serum miR‐4746‐5p in liver cancer patients after interventional chemotherapy and its possible mechanism14
Pelargonidin inhibits cell growth and promotes oxidative stress‐mediated apoptosis in lung cancer A549 cells14
Heparosan biosynthesis in recombinant Bacillus megaterium: Influence of N‐acetylglucosamine supplementation and kinetic modeling14
Bacoside‐A repressed the differentiation and lipid accumulation of 3T3‐L1 preadipocytes by modulating the expression of adipogenic genes13
Issue Information13
Monascin and ankaflavin—Biosynthesis from Monascus purpureus, production methods, pharmacological properties: A review13
Pterostilbene regulates cell proliferation and apoptosis in non‐small‐cell lung cancer via targeting COX‐213
In vitro evaluation of copper sulfide nanoparticles decorated with folic acid/chitosan as a novel pH‐sensitive nanocarrier for the efficient controlled targeted delivery of cytarabine as an anticancer13
Characterization and validation of fatty acid metabolism‐related genes predicting prognosis, immune infiltration, and drug sensitivity in endometrial cancer13
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Probiotic and Synbiotic Isolates From Whey Water and Fermented Rice Water Exert Compelling Wound‐Healing Efficacy in a Diabetic Mouse Model12
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Dual Inhibition of AChE and GST by 1,2,4‐Triazine‐3‐Amine: Integrated Biochemical, Computational, and Hepatotoxicity Insights12
Biosensing epidemic and pandemic respiratory viruses: Internet of Things with Gaussian noise channel algorithmic model12
Deciphering the role of fungus in degradation of polypropylene from hospital waste11
Increasing production of spinosad inSaccharopolyspora spinosaby metabolic engineering11
Pharmacological evaluation of the effects of enzymatically liberated fish oil on eosinophilic inflammation in animal models11
A Prediction Nomogram for Moderate‐to‐Severe Bronchopulmonary Dysplasia in Chinese Very Preterm Infants With Respiratory Distress: A Multi‑Center Prospective Study11
Exploration of Basidiomycetes for Anthraquinone Dyes Decolorization in Textile Wastewater11
Identification of dilated cardiomyopathy‐linked key genes by bioinformatics methods and evaluating the impact of tannic acid and monosodium glutamate in rats11
Plasmodium falciparum cysteine protease Falcipain 3: A potential enzyme for proteolytic processing of histone acetyltransferase PfGCN511
High‐level expression of functional Pfu DNA polymerase recombinant protein by mimicking the enhanced green fluorescence protein gene codon usage11
Ellagic acid as a potent anticancer drug: A comprehensive review on in vitro, in vivo, in silico, and drug delivery studies11
Expression, purification, and biological characterization of recombinant human interleukin‐31 protein11
Puerarin alleviates acrolein‐induced atherosclerosis by activating the MYH9‐mediated SIRT1/Nrf2 cascade to inhibit the activation of inflammasome11
Trichoderma asperellum as a novel source to prepare chitooligosaccharides by enzymatic hydrolysis and its antimicrobial activity11
Synthesis, Molecular Structure, and Antibacterial Efficacies of Transition Metal Azo‐Oximates of Fe(II) and Mn(II), a Sustainable Solution to Multidrug Resistance in Bacteria10
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The Annexin A1 Protein Mimetic Peptide Ac2‐26 prevents cellular senescence of CHON‐001 chondrocytes against tumor necrosis factor‐α via the Nrf2/NF‐κB pathway10
Enhancement of triterpene production via in situ extractive fermentation of Sanghuangporus vaninii YC‐110
Study on extraction and characterization of new antibiotics violacein from engineered Escherichia coli VioABCDE‐SD10
Retraction Statement: Long noncoding RNA linc‐ITGB1 promotes cell migration and invasion in human breast cancer10
A comprehensive review on fructosyl peptide oxidase as an important enzyme for present hemoglobin A1c assays10
Gentamicin‐Loaded Chitosan Nanocoating on Polyurethane Prostatic Stents to Combat Biofilm Formation and Urogenital Device‐Associated Infections10
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Association Between Different Types of Physical Activity and the Risk of COPD: A Cross‐Sectional NHANES Study9
Synthesis, physicochemical characterization, and in vitro evaluation of biodegradable PLGA nanoparticles entrapped to folic acid for targeted delivery of kaempferitrin9
Rapid identification of methicillin‐resistant Staphylococcus aureus by MALDI‐TOF MS: A meta‐analysis9
RETRACTION: Development of an Amperometric Biosensor That Can Determine the Amount of Glucose in the Blood Using the Glucose Oxidase Enzyme: Preparation of Polyaniline–Polypyrrole–Poly(sodium‐4‐styren9
Research Progress on Biosynthesis and Regulation of Conjugated Linoleic Acid in Lactic Acid Bacteria9
Salidroside alleviates imiquimod‐induced psoriasis by inhibiting GSDMD‐driven keratinocyte pyroptosis9
Bio‐Designed Carboxymethyl Chitosan/Polyvinyl Alcohol Hydrogel Containing Alpha‐Tocopherol as a Three‐Dimensional Wound Dressing, In Vitro and In Vivo Study9
Crystal structure determination, molecular docking, and molecular dynamics of arylal dimedones as potential inhibitors for castrate‐resistant prostate cancer9
Development of aptamer‐based ELISA method for d‐dimer detection9
Purification and characterization of a high molecular weight serine protease from Microbacterium paraoxydans sp. SKS109
TIGAR Alleviates Acute Pancreatitis by Suppressing Glycolysis Through the LAMP2/PI3K/Akt Axis9
Influence of Cell Physiological Status on the Intensified Fed‐Batch Cultures at Ultra‐High Seeding Density9
HPLC purification of antioxidant and antibacterial peptides from a lichen “Parmotrema perlatum (Huds.) M. Choisy”: Identification by LC‐MS/MS peptide mass fingerprinting9
5‐Aminoimidazole‐4‐carboxamide‐1‐β${\bf {\beta}}$‐ d ‐ribofuranoside ameliorates lipotoxicity through enhanced reticulophagy in HepG2 cells8
Synergistic cytotoxicity and in vitro antioxidant activity of hederagenin and its glycoside from quinoa8
The Impact of Hunched Posture on the Elasticity of the Upper and Middle Trapezius Muscles During Sedentary Activity8
Biotechnological Application of New Cold‐Active Protease From Aeromonas salmonicida subsp. salmonicida EDT18
Fish scale–derived hydroxyapatite for alveolar ridge preservation8
Review of electrochemical and optical biosensors for testosterone measurement8
Engineering of Ruthenium‐Based Anticancer Drug RAPTA‐C and Carvacrol Incorporated Hyaluronic Acid‐Altered Liposome Formulation for Ovarian Cells and Its Apoptosis Induction8
Issue Information8
Engineering processive cellulase of Clostridium thermocellum to divulge the role of the carbohydrate‐binding module8
Antagonistic Effects of Probiotic Lactobacillus Strains on Multidrug‐Resistant Staphylococcus aureus : Rol8
Enhanced Synthesis, Purification, and Characterization of a Marine Bacterial Consortium‐Derived Protease Enzyme With Destaining and Keratinolytic Activity8
Waste cooking oil and molasses for the sustainable production of extracellular lipase by Saitozyma flava8
Computational insights in design of Crimean–Congo hemorrhagic fever virus conserved immunogenic nucleoprotein peptides containing multiple epitopes8
Exploiting Self‐Immobilized Fungi for Biovalorization of Oil Palm Sap to Organic Acids Through Repeated‐Batch Fermentation8
Bacterial cellulose: Nature's greener tool for industries7
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Analysis of genes specific to the early maturation stage of Sesamum indicum seeds by subtraction method*,**7
Investigation of Antioxidant, Antimicrobial Potential, Soil Nutriology, and Molecular Docking Study of Bioactive Compounds of Eleusine coracana (Finger Millet), Pennisetum glaucum (Pearl7
Adaptive and Biochemical Responses of Dictyosphaerium sp. AM‐2024a to Environmental Conditions and Microplastic Interactions: Synergy of Biofuel Production With Pollution Mitigation7
Production and application of purified mutanase from novel Cellulosimicrobium funkei SNG1 in the in vitro biofilm degradation7
Mutagenesis Breeding and Liquid Surface Culture Strategy for R‐2‐(4‐Hydroxyphenoxy) Propionic Acid‐Producing Strains7
Artificial Neural Network: Optimization and Characterization of α‐Amylase Production from Bacillus velezensis Species7
Cell membrane biomimetic nanoparticles in drug delivery7
Vitamin K: A novel cancer chemosensitizer7
Production and Formulation of Alcanivorax borkumensis SK2 Cell Powders for Marine Oil Spill Bioremediation7
Issue Information7
Preparation and characterization of biogenic silver nanoparticles using Strobilanthes cordifolia (Vahl) J.R.I. Wood leaves and its biological applications6
Unraveling the potential of bacterial phytases for sustainable management of phosphorous6
Extraction process, physicochemical properties, and digestive performance of red yeast rice starch6
Chromofungin mitigates free fatty acids‐induced endothelial inflammation via inhibition of NOD‐like receptor thermal protein domain‐associated protein 3 mediated by adenosine 5ʹ‐monophosphate‐activate6
Matrix Metalloproteinases 9 Contributes to Inflammatory Responses in Helicobacter pylori‐Positive Gastric Cancer6
Immobilization of the metagenomic lipase, LipG9, on porous pellets of poly‐hydroxybutyrate produced by the double emulsion solvent evaporation technique6
Synthesis, enzyme inhibition, and molecular docking studies of a novel chalcone series bearing benzothiazole scaffold6
Spontaneous nanoemulsification of cinnamon essential oil: Formulation, characterization, and antibacterial and antibiofilm activity against fish spoilage caused by Serratia rubidaea BFMO86
Recent development on nanomaterial‐based biosensors for identifying thyroid tumor biomarkers6
Analysis of the main bioactive compounds from Ocimum basilicum for their antimicrobial and antioxidant activity6
Rheum ribes extract‐loaded nanoliposome as a novel phytogenic antibiotic alternative in mice challenged by Escherichia coli (O157:H7)6
Analysis of human epidermal growth factor receptor 2 interaction on aptamer‐probed interdigitated electrode for breast cancer diagnosis6
Organ toxicities associated with diet‐induced obesity in rats: Investigation of changes in activities selected enzymes6
Stability in human serum and plasma of the HIV peptide drug candidate CIGB‐210 and improved variants6
Deciphering the prognostic landscape of triple‐negative breast cancer: A focus on immune‐related hub genes and therapeutic implications6
Antioxidant activity and cytotoxicity of greigite nanoparticles synthesized by hydrothermal technique6
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Development of the degradation bacteria in household food waste and analysis of the microbial community in aerobic composting6
Relaxin‐2 promotes osteoblastic differentiation mediated by epidermal growth factor and epidermal growth factor receptor signaling6
A multifactorial assessment of the SRP pathway constituent FtsY as a vital mycobacterial constituent6
Ameliorative effect of rutecarpine supplementation against cisplatin‐induced nephrotoxicity in rats via inhibition of monocyte chemoattractant protein‐1, intercellular adhesion molecule‐1, high‐mobili6
Peroxidases and Peroxidase‐Mimicking Capacities of Copper Nanozymes: Catalytic Mechanism, Applications, and Properties‐A Review6
Plasma Exosomal circRNAs as Potential Biomarkers for Patients with Septic Shock‐Induced Acute Kidney Injury6
Optimized rapid production of recombinant secreted proteins in CHO cells grown in suspension: The case of RBD5
CircMYO1C silencing alleviates chondrocytes inflammation and apoptosis through m6A/HMGB1 axis in osteoarthritis5
Study on the antibacterial effect of CuO nanoparticles on Klebsiella pneumonia bacteria: Efficient treatment for colorectal cancer5
In Silico Identification of 9‐Amino Camptothecin as a Dual Inhibitor of VEGF‐A and VEGF‐B in N1–N8 Breast Cancer5
Production of the prolyl endoprotease (PEP) from Aspergillus sp. FSDE 16 by solid‐state fermentation (SSF) and use for producing a gluten‐free beer5
β‐Catenin‐treated peptides effectively inhibit the proliferation of colorectal cancer5
Identification of MDM4 as a Prognostic Biomarker and a Target for Therapeutics in Colorectal Cancer5
Applications of a biocompatible alginate/pericardial fluid‐based hydrogel for the production of a bioink in tissue engineering5
RBPMS‐AS1 sponges miR‐19a‐3p to restrain cervical cancer cells via enhancing PLCL1‐mediated pyroptosis5
Exosomes derived from rapamycin‐treated 4T1 breast cancer cells induced polarization of macrophages to M1 phenotype5
Ornamental cabbage (Brassica oleracea var. acephala) responses to phytase enzyme purified from Lactobacillus coryniformis application5
Lipocalin‐2 Determination on Multiwalled Carbon Nanotube Integrated Circular Electrodes for Diagnosing Ulcerative Colitis5
A New Era for Using Natural Pigments: The Case of the C 50 Carotenoid Called Bacterioruberin5
Oxidoreductase enzymes: Characteristics, applications, and challenges as a biocatalyst5
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Rosmanol Suppresses Nasopharyngeal Carcinoma Cell Proliferation and Enhances Apoptosis, the Regulation of MAPK/NF‐κB Signaling Pathway5
Self‐assembled free nanocarrier prodrugs based on camptothecin and dihydroartemisinin exhibit accumulation and improved anticancer efficacy5
Low RYR2 Level Relates to Poor Prognosis of Patients With Lung Adenocarcinoma by Promoting Tumor Cell Proliferation and Inhibiting Immune Cell Infiltration5
Construction of an Osteoarthritis Diagnostic Model Based on Hub Immune Cells and Genes by Machine Learning Method5
Improving the extraction yield of essential oil from Pimenta dioica (L.) Merr. using Aspergillus niger ATCC 1004 enzyme blend5
Strategies to Express Soluble Recombinant Apostichopus japonicus Phospholipase A 2 in 5
Antibacterial activity of curcumin and its essential nanoformulations against some clinically important bacterial pathogens: A comprehensive review5
Development of a “turn off–on” whole‐cell biosensor for sulforaphane detection based on the ultrasensitive activator HrpRS5
Revealing the Taxonomic Profile of a Wild Edible Mushroom From Tribal Cuisine and Its Pharmacological Significance5
Optimization and chemical free fabrication of green synthesized iron nanoparticles as potential MRI contrast agent5
Evaluation of 2‐Aminothiazoles as α‐Glucosidase Inhibitors: DFT, Molecular Docking, and Antioxidant Studies5
Enzymatic Properties and Structural Insights Into the Derhamnosylating Alkaline α‐l‐Rhamnosidase From Aspergillus flavus5
Construction of Hollow Mesoporous Selenium Loaded With Carboplatin and Clacked With Bevacizumab‐Functionalized Albumin Nanoparticles for HER2+ Lung Cancer5
Immunogenicity of different nanoparticle adjuvants containing recombinant RBD coronavirus antigen in animal model5
CB‐0821, a novel CC chemokine receptor 5 (CCR5) inhibitor with improved binding efficacy proposed as anti‐HIV candidate: Computational and in vitro approach5
Investigation of resveratrol as a xanthine oxidase inhibitor: Mechanistic insights and therapeutic implications for gout and hyperuricemia4
Methyl Gallate: A Potent Bioactive Compound Promoting Osteogenic Differentiation by Regulating Runx2 and Cbfa1 in Osteoblastic Cell Lines4
Investigation of the effects of thiazole compounds on thioredoxin reductase 1 (TrxR1), glutathione S‐transferase (GST), and glutathione reductase (GR) targeted human brain glioblastoma cancer (4
Prognostic and Diagnostic Value of Platelet Distribution Width in COPD Patients with Pulmonary Hypertension: A Retrospective Study4
Marine‐Derived Molecular Glue Degraders: A New Frontier in Targeted Protein Degradation for Treatment of Multi‐Factorial Diseases4
Design of casein‐based nanocarriers for targeted delivery of daunorubicin to leukemia cells4
Comparing proteome changes involved in biofilm formation byStreptococcus mutansafter exposure to sucrose and starch4
Overproduction of bacterial cellulose from Acetobacter xylinum BPR2001 using food industries wastes4
Inhibition of USP21 leads to ovarian carcinoma cell death by suppressing MAPK signaling4
Protective effect of Pueraria lobata leaves on doxorubicin‐induced myocardial infarction in experimental Wistar rats4
PRKAA2 Promotes Tumor Growth and Inhibits Ferroptosis through SLC7A11/GSH/GPX4 Pathway in Non‐Small Cell Lung Cancer4
Biopharmaceutical applications of α‐galactosidases4
Inhibitory activity of Limosilactobacillus reuteri isolated from camel milk against Helicobacter pylori effects in human gastric epithelial cells4
ALKBH5 modulates bone cancer pain in a rat model by suppressing NR2B expression4
Research Progress Fusion Tags for Recombinant Protein Production4
Bioactivity of fluorophenyl thiourea derivatives: Antioxidant efficacy and inhibition of key diabetes‐related enzymes4
Screening, characterization, and optimization of the fermentation conditions of a novel cellulase‐producing microorganism from soil of Qinghai–Tibet Plateau4
A Sustainable Approach for Synthesis of Chitin Nanofibers From Rhizopus stolonifer AUMC 10992: Its Characterization and Application for Biosorption of Di4
Optimization of the hongqu starter preparation process for the manufacturing of red mold rice with high gamma‐aminobutyric acid production by solid‐state fermentation4
The Stem Cell Transcription Factor OCT4 Silences Target DNA Methyltransferase 1 to Strengthen DNA Damage Response in Cisplatin‐Treated Gastric Cancer Cells4
Alleviation of dental caries by use of isolated potential probiotic and its characterization4
Uninterrupted real‐time cerebral stress level monitoring using wearable biosensors: A review4
Immunoinformatic approach to design an efficient multi‐epitope peptide vaccine against melanoma4
Selenized lactic acid bacteria microencapsulated by spray drying: A promising strategy for beef cattle feed supplementation4
Fortified Food With Withania Somnifera Modulates Glucose Metabolism in STZ‐Induced Hyperglycemia in Rats4
A promising eco‐friendly and cost‐effective photocatalytic rolled graphene oxide/poly(m‐methylaniline) core–shell nanocomposite for antimicrobial action4
Protective effect of bromelain on some metabolic enzyme activities in tyloxapol‐induced hyperlipidemic rats4
Optimization of reduced graphene oxide production using central composite design from Pennisetum glaucum for biomedical applications4
Analysis of highly frequent point mutations in glycoprotein C, glycoprotein N, and nucleoprotein of CCHFV4
Homology modeling, virtual screening, molecular docking, and ADME approaches to identify a potent agent targeting NK2R protein4
Acacetin Prevents Renal Damage Induced by Streptozotocin via Altering the NF‐κB/ASC/NLRP3 and AMPK/SIRT1 Pathways in Mice4
Alchemy of Fungi and AI: Response Surface Methodology and Artificial Neural Network‐Based Optimization of Echinocandin B Production in Aspergillus nidulans4
Berberine Alleviates Chronic Restraint Stress‐Induced Depression‐Like Behavior by Modulating Gut Microbiota and SCFA Production in Mice4
Yeasts as Biofertilizers and Biocontrol Agents: Mechanisms and Applications4
Issue Information4
Mucilage‐assisted fabrication of molybdenum trioxide nanostructures for photothermal ablation of breast cancer cells4
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