Biotechnology and Applied Biochemistry

Papers
(The TQCC of Biotechnology and Applied Biochemistry is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)
ArticleCitations
A two‐step electrochemical biosensor based on Tetrazyme for the detection of fibrin281
Computational analysis and in vitro evaluation of TMF 104, for its antioxidant, antimicrobial, and anticancer efficacies165
Retraction Statement: Knockdown of GPR137 by RNAi inhibits pancreatic cancer cell growth and induces apoptosis103
SSB‐2548 Inhibits CXCR‐4 Activation, Inducing Apoptosis in Acute Myeloid Leukemia Cells85
S100A10 regulates tumor necrosis factor alpha‐induced apoptosis in chondrocytes via the reactive oxygen species/nuclear factor‐kappa B pathway54
The antibacterial mechanism of perilla rosmarinic acid52
Exploration of potential inhibitors for SARS‐CoV‐2 Mpro considering its mutants via structure‐based drug design, molecular docking, MD simulations, MM/PBSA, and DFT calculations37
A stable biosensor for organophosphorus pesticide detection based on chitosan modified graphene36
Culture optimization to enhance carotenoid production of a selected purple nonsulfur bacterium and its activity against acute hepatopancreatic necrosis disease‐causing Vibrio parahaemolyticus33
Human genome‐wide analysis and identification of the hyperphosphorylation‐elicited interactions between subarachnoid tau protein and phosphoprotein‐binding domains31
A new molecularly imprinted polymer electrochemical sensor based on CuCo2O4/N‐doped CNTs/P‐doped GO nanocomposite for detection of 25‐hydroxyvitamin D3 in serum sample31
Immobilization‐free electrochemical DNA sensor based on signal cascade amplification strategy28
Development and validation of ELISA for screening of Kratom (Mitragyna speciosa) habitual users using urinary AZ122 biomarker27
Sulfonamide derivatives with benzothiazole scaffold: Synthesis and carbonic anhydrase I–II inhibition properties27
High‐throughput screening for distinguishing nitrilases from nitrile hydratases in Aspergillus and application of a Box–Behnken design for the optimization of nitrilase26
Osteogenically differentiated mesenchymal stem cells promote the apoptosis of human umbilical vein endothelial cells in vitro25
Nanosensing colon cancer biomarker on zeolite‐modified gap‐fingered dielectrodes24
23
Complete genome sequencing and comparative genome analysis of the extremely halophilic archaea, Haloterrigena daqingensis21
Application of Deconica castanella ligninolytic enzymatic system in the degradation of hexachlorobenzene in soil21
High‐sensitivity immunoassay on interdigitated electrode to detect osteoporosis biological marker21
Improving the substrate binding of acetyl‐CoA carboxylase (AccB) from Streptomyces antibioticus through computational enzyme engineering18
The effect of thyme essential oil and endothelial progenitor stem cells on lipopolysaccharide‐induced sepsis in C57BL/6 mice17
Analysis of genes specific to the early maturation stage of Sesamum indicum seeds by subtraction method*,**17
17
Efficient coexpression of recombinant human fusion collagen with prolyl 4‐hydroxylase from Bacillus anthracis in Escherichia coli17
Spectroscopic analysis of recombinant human growth hormone in the presence of sucrose and trehalose16
Sunlight‐driven antibacterial activity of a novel zinc oxide quantum dot and its optimization using Box–Behnken design—A medicament for communicable disease protective wearables16
Photofermentative biohydrogen generation from organic acids by Rhodobacter sphaeroides O.U.001: Computational fluid dynamics modeling of hydrodynamics and temperature15
Stem cell‐based and mesenchymal stem cell derivatives for coronavirus treatment15
Analysis of the main bioactive compounds from Ocimum basilicum for their antimicrobial and antioxidant activity15
The first in‐depth exploration of the genome of the engineered bacterium, Gluconobacter thailandicus15
Identification and characterization of a novel bacteriocin gene cluster in Lysinibacillus boronitolerans14
Issue Information14
Inhibition of glutathione reductase uncovers the activation of NADPH‐inhibited glucose‐6‐phosphate dehydrogenase14
Issue Information13
UPLC‐PDA coupled HR‐TOF ESI/MS2‐based identification of derivatives produced by whole‐cell biotransformation of epothilone A using Nocardia sp. CS692 and a cytochrome P450 overexpres13
A fluorescent screening method for optimization of conotoxin expression in Pichia pastoris13
Preparation and characterization of a polyclonal antibody against PTEN‐Long13
Rheum ribes extract‐loaded nanoliposome as a novel phytogenic antibiotic alternative in mice challenged by Escherichia coli (O157:H7)12
Neuroprotective effects of annexin A1 tripeptide in rats with sepsis‐associated encephalopathy12
Design and simulation of a novel integrated microfluidic chip for cell isolation and culture12
Artificial Neural Network: Optimization and Characterization of α‐Amylase Production from Bacillus velezensis Species12
GlnR‐mediated regulation of KstR controls cholesterol catabolism in Mycobacterium smegmatis12
Pemetrexed loaded gold nanoparticles as cytotoxic and apoptosis inducers in lung cancer cells through ROS generation and mitochondrial dysfunction pathway12
Biocompatible phospholipid‐based nanovesicular drug delivery system of ketoprofen: Systematic development, optimization, and preclinical evaluation12
Issue Information12
Improving squalene production by blocking the competitive branched pathways and expressing rate‐limiting enzymes in Rhodopseudomonas palustris12
Development of the degradation bacteria in household food waste and analysis of the microbial community in aerobic composting12
Production and application of purified mutanase from novel Cellulosimicrobium funkei SNG1 in the in vitro biofilm degradation11
Dual Targeting of MEK1 and Akt Kinase Identified SBL‐027 as a Promising Lead Candidate to Control Cell Proliferations in Gastric Cancer11
Metal‐free Sulfur‐doped graphitic carbon nitride‐modified GCE‐based electrocatalyst for the enhanced electrochemical determination of Omeprazole in Drug formulations and Biological Samples11
Exploring in vitro effect of silver nanoparticles and Holothuria parva extracts on kinetics and stability of α‐amylase11
Green synthesis of glyco‐phenol by enzymatic coupling between ferulic acid and glucosamine: An ecofriendly procedure11
Bioconversion of lovastatin to simvastatin by Streptomyces carpaticus toward the inhibition of HMG‐CoA activity11
Dysbiosis of pro‐inflammatory and anti‐inflammatory salivary cytokines during psoriasis providing a therapeutic window and a valuable diagnostic aid in future11
Withdrawal10
A review of highly sensitive electrochemical genosensors for microRNA detection: A novel diagnostic platform for neurodegenerative diseases diagnostics10
Antibacterial metabolites from an unexplored strain of marine fungiEmericellopsis minimaand determination of the probable mode of action againstStaphylococcus aureusand methicillin‐resis10
A GH42 β‐galactosidase from Bifidobacterium thermophilum: Biochemical characterization and synthesis of galactosyl glycerol by reverse hydrolysis10
Enzymatic properties of ornithine decarboxylase from Clostridium aceticum DSM149610
Current advances in Candida tropicalis: Yeast overview and biotechnological applications10
Time‐resolved fluorescence immunoassay (TRFIA) for the simultaneous detection of hs‐CRP and lipoprotein(a) in serum10
Identification of osteosarcoma by microRNA‐coupled nuclease digestion on interdigitated electrode sensor10
Preparation and in vitro characterization of histidine trimethyl chitosan conjugated nanocomplex incorporated into injectable thermosensitive hydrogels for localized gene delivery9
Virtual screening of plant‐derived molecules against zinc‐dependent imipenemases in class B metallo‐β‐lactamases of Acinetobacter baumannii9
Isolation and neuronal apoptosis inhibitory property of bacoside‐A3 via downregulation of β‐amyloid induced inflammatory response9
Zinc oxide and gold textured Janus nanowire integration in an impedimetric sensor for leptospirosis DNA‐biomarker recognition9
Annexin A1 protects periodontal ligament cells against lipopolysaccharide‐induced inflammatory response and cellular senescence: An implication in periodontitis9
Chromosomal editing of Corynebacterium glutamicum ATCC 13032 to produce gamma‐aminobutyric acid9
Bacterial cellulose: Nature's greener tool for industries9
Biosensor as an alternative diagnostic method for rabies virus detection: A literature review9
Designing a novel multi‐epitope antigen for diagnosing human cytomegalovirus infection: An immunoinformatics approach9
Evaluation of the relationship of cytokines concentrations tumor necrosis factor‐alpha, interleukin‐6, and C‐reactive protein in obese diabetics and obese non‐diabetics: A comparative study9
Genus Streptomyces: Recent advances for biotechnological purposes9
Cell membrane biomimetic nanoparticles in drug delivery8
Effect of the activation strategy of nickel oxide‐multi‐walled carbon nanotubes on the immobilization of xylanase for synthesis of xylooligosaccharides8
Correction to “Retraction”8
orexin B alleviates sepsis‐associated lung injury through the attenuation of pulmonary endothelial barrier dysfunction by regulating the rho‐associated coiled‐coil containing protein kinase 2/zonula o8
Unraveling the potential of bacterial phytases for sustainable management of phosphorous8
Correction to “Retraction”8
Activation of GPR55 alleviates neuropathic pain and chronic inflammation8
Nuciferine from Nelumbo nucifera Gaertn. attenuates isoproterenol‐induced myocardial infarction in Wistar rats7
Gold nanourchin on multiple‐point dielectrode for glucose biosensing by current‐potential measurement7
Chitosan‐enhanced sensitivity of mercaptoundecanoic acid (MUA)‐ capped gold nanorod based localized surface plasmon resonance (LSPR) biosensor for detection of alpha‐synuclein oligomer biomarker in pa7
Fabrication of Bioconjugates Clacked Chitosan‐Coated SN‐38 Liposomal Nanoparticles: Improved Precise Chemotherapy Efficacy in Lung Cancer Cells and Its Apoptosis7
An electrochemical aptasensor for detection of prostate‐specific antigen‐based on carbon quantum dots‐gold nanoparticles7
Combination MEG3 lncRNA and Ciprofloxacin dramatically decreases cell migration and viability as well as induces apoptosis in GC cells in vitro7
EGF‐functionalized lipid–polymer hybrid nanoparticles of 5‐fluorouracil and sulforaphane with enhanced bioavailability and anticancer activity against colon carcinoma7
Successful use of Nicotiana tabacum hairy roots for the recombinant production of Cecropin A peptide7
Neuroprotective effect of biogenically synthesized ZnO nanoparticles against oxidative stress and β‐amyloid toxicity in transgenic Caenorhabditis elegans7
Sensitive silica‐alumina modified capacitive non‐Faradaic glucose sensor for gestational diabetes7
Collagen‐coated agarose–chitosan scaffold used as a skin substitute7
N‐acetyl‐L‐cysteine ameliorates gestational diabetes mellitus by inhibiting oxidative stress7
6
Identification and structural prediction of the unrevealed amidohydrolase enzyme: Pterin deaminase from Agrobacterium tumefaciens LBA44046
Development of a continuous fermentation process for the production of recombinant uricase enzyme by Pichia pastoris6
RETRACTED: Development of an amperometric biosensor that can determine the amount of glucose in the blood using the glucose oxidase enzyme: Preparation of polyaniline–polypyrrole–poly(sodium‐4‐styrene6
Serum‐free medium for recombinant protein expression in insect cells6
Inhibitory effects of Gracilaria edulis and Gracilaria salicornia against the MGMT and VEGFA biomarkers involved in the onset and advancement of glioblastoma using in silico and <6
6
Apelin‐13 Alleviates Diabetes‐Associated Cognitive Decline by Reducing Oxidative Stress and Mitochondrial Dysfunction via the SIRT3/Foxo3 Pathway6
The anti‐spermatogenic activity of nanoliposomes loaded with Heracleum persicum phenolic compounds in Balb/C mice6
Different experimental approaches for Fourier‐transform infrared spectroscopy applications in biology and biotechnology: A selected choice of representative results6
Glucose oxidase: Applications, sources, and recombinant production6
Ohwia caudata inhibits doxorubicin‐induced cardiotoxicity by regulating mitochondrial dynamics via the IGF‐IIR/p‐Drp1/PARP signaling pathway6
Artemisia argyi mitigates doxorubicin‐induced cardiotoxicity by inhibiting mitochondrial dysfunction through the IGF‐IIR/Drp1/GATA4 signaling pathway6
Alginate‐derived carbon dots for “turn off–on” anti‐neoplastic 5‐fluorouracil sensing in biological samples6
hsa_circ_0000129 targets miR‐383‐5p/tropomyosin 3 axis to facilitate ovarian cancer progression6
Pelargonidin inhibits cell growth and promotes oxidative stress‐mediated apoptosis in lung cancer A549 cells6
Construing recombinant ZFP160 from Aspergillus terreus as pterin deaminase enzyme6
Cell‐free protein synthesis system: A new frontier for sustainable biotechnology‐based products6
Optimizing recombinant antibody fragment production: A comparison of artificial intelligence and statistical modeling6
Evaluation of the therapeutic action of original antiviral drug in SARS‐CoV‐26
Issue Information6
Immunogenic cell death–related genes predict prognosis and response to immunotherapy in lung squamous cell carcinoma6
Relaxin‐2 promotes osteoblastic differentiation mediated by epidermal growth factor and epidermal growth factor receptor signaling6
Synthesis and Characterization of Brucine Gold Nanoparticles for Targeted Breast Cancer Therapy: Mechanistic Insights into Apoptosis and Antioxidant Disruption in MCF‐7 Cells5
Use of antioxidant nanoparticles to reduce oxidative stress in blood storage5
Induced effect of Ca2+ and Al3+ on chaetominine synthesis by Aspergillus fumigatus CY018 under submerged fermentation5
Evaluation of the effect of designed PLGA‐arctiin nanoparticles modified with folic acid and chitosan on colon cancer cells5
Study of the properties of carotenoids and key carotenoid biosynthesis genes from Deinococcus xibeiensis R135
Antimicrobial effect of pimozide by targeting ROS‐mediated killing in Staphylococcus aureus5
Urea biosensors: A comprehensive review5
Chromofungin mitigates free fatty acids‐induced endothelial inflammation via inhibition of NOD‐like receptor thermal protein domain‐associated protein 3 mediated by adenosine 5ʹ‐monophosphate‐activate5
Lipase immobilization on biodegradable film with sericin5
Anemonin inhibits sepsis‐induced acute kidney injury via mitigating inflammation and oxidative stress5
Preparation of silver nanoparticles by Osbeckia stellata aqueous extract via green synthesis approach: Characterization and assessment of their antioxidant, antidiabetic, cytotoxicity, and anti5
Reconnoitring the antioxidant and antibacterial potential of different fruits after tannin acyl hydrolase mediated biotransformation5
Enhancement of astaxanthin production from food waste by Phaffia rhodozyma screened by flow cytometry and feed application potential5
Plasma Exosomal circRNAs as Potential Biomarkers for Patients with Septic Shock‐Induced Acute Kidney Injury5
Advancement in biosensor: “Telediagnosis” and “remote digital imaging”5
Examination of the effect of curcumin in experimental liver damage created by diethylnitrosamine in Swiss albino mice to superoxide dismutase and catalase activities and glutathione, malondialdehyde, 5
Concanavalin A–activated magnetic nanoparticles as an affine material for urinary exosome isolation5
Biosensor based on bimetallic/graphene composite for non‐enzymatic detection of hydrogen peroxide in living tumor cells5
Poly‐γ‐glutamic acid overproduction of Bacillus licheniformis ATCC 9945a by developing a novel optimum culture medium and glutamate pulse feeding using different experimental design 5
5
Evaluation of antityrosinase activity and mechanism, antioxidation, and UV filter properties of theaflavin5
trans‐Ferulic Acid Antagonizes the Anti‐Inflammatory Activity of Etoricoxib: Possible Interaction of COX‐1 and NOS5
Synthesis and characterization of piperine‐modified mesoporous silica nanoparticles for biomedical applications5
Issue Information5
Gold nanourchin enhances detection of Alzheimer's disease biomarker “miRNA‐137” on dual electrode sensing surface5
Spontaneous nanoemulsification of cinnamon essential oil: Formulation, characterization, and antibacterial and antibiofilm activity against fish spoilage caused by Serratia rubidaea BFMO85
Deciphering the prognostic landscape of triple‐negative breast cancer: A focus on immune‐related hub genes and therapeutic implications5
Long noncoding RNA CASC2 protect ROS‐induced oxidative stress in myocardial infarction by miR‐18a/SIRT25
Study of selenium enrichment metabolomics in Bacillus subtilis BSN313 via transcriptome analysis5
Escherichia coli cytosine deaminase: Structural and biotechnological aspects4
Epigenetic and somaclonal divergence in Dendrocalamus farinosus for physiological augmentation and lignin degradation4
Issue Information4
Skin wound healing in diabetic rat model using low‐dose photodynamic therapy4
The analysis of methylxanthine fractions obtained from Camellia sinensis cultivated in Turkey and effects on the in vitro inhibition of CYP2D6 enzyme4
Construction, expression, purification, characterization, and structural analysis of microbial transglutaminase variants4
Protective effect of human epicardial adipose‐derived stem cells on myocardial injury driven by poly‐lactic acid nanopillar array4
Thrombolytic and anticoagulant efficiencies of purified fibrinolytic enzyme produced from Cochliobolus hawaiiensis under solid‐state fermentation4
Liposomes: Ideal drug delivery systems in breast cancer4
Some indazoles as alternative inhibitors for potato polyphenol oxidase4
Computational modeling and in vitro evaluation identified natural product—Z218 as a novel Janus kinase 2 (JAK2) inhibitor to combat β‐thalassemia4
Effects of trehalose and ergosterol on pinene stress of Candida glycerinogenes4
Isolation and structural characterization of exopolysaccharide from the Cordyceps cicadae and the immunomodulatory activity on RAW264.7 cells4
Extraction process, physicochemical properties, and digestive performance of red yeast rice starch4
A comparative molecular dynamic simulation study on potent ligands targeting mTOR/FRB domain for breast cancer therapy4
Fabrication of bovine serum albumin‐polyethylene glycol nanoparticle conjugated‐folic acid loaded‐naringenin as an efficient carrier biomacromolecule for suppression of cancer cells4
4
Nimotuzumab and irinotecan synergistically induce ROS‐mediated apoptosis by endoplasmic reticulum stress and mitochondrial‐mediated pathway in cervical cancer4
Synthesis and characterization of N‐rich fluorescent bio‐dots as a reporter in the design of dual‐labeled FRET probe for TaqMan PCR: A feasibility study4
Enzymatic production of wax esters by esterification using lipase immobilized via physical adsorption on functionalized rice husk silica as biocatalyst4
Issue Information4
Harnessing Microbial Signal Transduction Systems in Natural and Synthetic Consortia for Biotechnological Applications4
A multifactorial assessment of the SRP pathway constituent FtsY as a vital mycobacterial constituent4
An investigation on the c‐MYC, AXIN1, and COL11A1 gene expression in colorectal cancer4
Biosensing human blood clotting factor by dual probes: Evaluation by deep long short‐term memory networks in time series forecasting4
In silico–guided synthesis of a new, highly soluble, and anti‐melanoma flavone glucoside: Skullcapflavone II‐6′‐Oβ‐glucoside4
In vitro and in vivo assessment of antimicrobial, enzymatic, and antifouling properties of self‐potent lichen symbiotic bacteria4
Strategies on aroma formation in Chardonnay sparkling base wine: Different Saccharomyces cerevisiae strains, co‐inoculation with Torulaspora delbrueckii and utilization of bentonite4
Overview of cloning in lactic acid bacteria: Expression and its application of probiotic potential in inflammatory bowel diseases4
4
Silica nanoparticle‐modified microcomb electrode for voltammetry detection of osteopontin with high sensitivity4
Issue Information4
Analysis of human epidermal growth factor receptor 2 interaction on aptamer‐probed interdigitated electrode for breast cancer diagnosis4
Protective effect of a reverse membrane bioreactor against toluene and naphthalene in anaerobic digestion4
Optimization of Culture Medium Ingredients and Culture Conditions for Bacteriocin Production in Lactococcus lactis NCU0360194
Analysis of the effects of different nitrogen sources and calcium on the production of amphotericin by Streptomyces nodosus based on comparative transcriptome4
Pectinases as promising green biocatalysts having broad‐spectrum applications: Recent trends, scope, and relevance4
Production and stability of pigments by Talaromyces purpurogenus LC128689 in an alternating air phase–liquid phase cultivation system4
Zerumbone‐induced reactive oxygen species‐mediated oxidative stress re‐sensitizes breast cancer cells to paclitaxel4
In vitro antibacterial activity of antibiotics and plant essential oils against Escherichia coli MTCC443 supported through the molecular docking and pharmacokinetics study4
Tetrahydropalmatine from medicinal plants activates human glucokinase to regulate glucose homeostasis4
0.053941011428833