OOIR: Observatory of International Research

Papers

(The H4-Index of Proteins-Structure Function and Bioinformatics is 31. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-07-01 to 2025-07-01.)

Article	Citations
	421
Issue Information ‐ Forthcoming	338
	283
iNucRes‐ASSH: Identifying nucleic acid‐binding residues in proteins by using self‐attention‐based structure‐sequence hybrid neural network	162
Functional characterization of a hypothetical protein (TTHA1873) from Thermus thermophilus	154
Unraveling the Structural Basis of Biased Agonism in the β₂‐Adrenergic Receptor Through Molecular Dynamics Simulations	102
Protein‐Ligand Structure and Affinity Prediction in CASP16 Using a Geometric Deep Learning Ensemble and Flow Matching	79
Development of a Novel Method for Representing 3D Structures of Nucleotides Using the Concept of the TSR Algorithm and Evaluation of the Method Through Studying Specific Interactions Between DNAs and	78
Application of AlphaFold models in evaluating ligandable cysteines across E3 ligases	57
Oxygen‐insensitive nitroreductase E. coliNfsA, but not NfsB, is inhibited by fumarate	57
Conserved features of the MlaD domain aid the trafficking of hydrophobic molecules	55
Prediction of protein assemblies, the next frontier: The CASP14‐CAPRI experiment	55
Design and characterization of a novel dimeric blood–brain barrier penetrating TNFα inhibitor	54
Evolutionary models of amino acid substitutions based on the tertiary structure of their neighborhoods	53
SARS‐CoV‐2 neutralizing antibody epitopes are overlapping and highly mutated which raises the chances of escape variants and requires development of broadly reactive vaccines	52
Order/Disorder Transitions Upon Protein Binding: A Unifying Perspective	52
Analyzing the cation‐aromatic interactions in proteins: Cation‐aromatic database V2.0	48
Multiscale MD simulations of wild‐type and sickle hemoglobin aggregation	45
rrQNet: Protein contact map quality estimation by deep evolutionary reconciliation	44
New simulation insights on the structural transition mechanism of bovine rhodopsin activation	43
Molecular dynamics studies of CED‐4/CED‐9/EGL‐1 ternary complex reveal CED‐4 release mechanism in the linear apoptotic pathway of Caenorhabditis ele	42
Comparative analysis of permanent and transient domain–domain interactions in multi‐domain proteins	41
Protein structuromics: A new method for protein structure–function crosstalk in glioma	39
Molecular dynamics analysis of a flexible loop at the binding interface of the SARS‐CoV‐2 spike protein receptor‐binding domain	38
Crystal structure of GTP‐dependent dephospho‐coenzyme A kinase from the hyperthermophilic archaeon, Thermococcus kodakarensis	37

Issue Information ‐ Table of Content	37
Issue Information ‐ Forthcoming	37
An Overview of Property, Design, and Functionality of Linkers for Fusion Protein Construction	36
Fusion of two unrelated protein domains in a chimera protein and its 3D prediction: Justification of the x‐ray reference structures as a prediction benchmark	33
Tyrosine 288 in the extracellular domain of the human P2X7 receptor is critical for receptor function revealed by structural modeling and site‐directed mutagenesis	33
Thermodynamic consequences of stapling side‐chains on a peptide ligand using a lactam‐bridge: A theoretical study on anti‐angiogenic peptides targeting VEGF	32
DynaBiS: A hierarchical sampling algorithm to identify flexible binding sites for large ligands and peptides	31
Identification of key stabilizing interactions of amyloid‐β oligomers based on fragment molecular orbital calculations on macrocyclic β‐hairpin peptides	31