Reproductive Toxicology

Article	Citations
Mechanisms underlying impaired spermatogenic function in orchitis induced by busulfan	134
RETRACTED: Overexpressed miR-106b-5p promotes epithelial-mesenchymal transition in endometriosis by targeting PTEN	72
Modulatory role of Bovine serum albumin conjugated manganese dioxide nanoparticle on microwave radiation induced alterations in reproductive parameters of rat	65
Perfluoroalkyl substances (PFAS) exposure and preeclampsia risk: Impaired angiogenesis through suppression of VEGF signaling	50
Fucoxanthin mitigates mercury-induced mitochondrial toxicity in the human ovarian granulosa cell line	48
Evaluation of reproductive toxicology studies according the OECD Guideline 443 – Claim and reality	42
Chronic fat consumption affects metabolic aspects of murine physiology and influences ovarian follicle atresia	40
Small extracellular vesicles derived from Nrf2-stimulated bone marrow mesenchymal stem cells ameliorated the testis damage and fertility disorder in doxorubicin-treated mice	39
Single- and combined-heavy metals/metalloids exposures are associated with infertility in US women aged 20–44: NHANES 2013–2020 analysis	36
Acetaminophen overdose inhibits steroidogenic acute regulatory protein expression by reducing AKT-mediated SP1 expression in human granulosa-lutein cells	35
Investigation of potential toxic effects of nano- and microplastics on human endometrial stromal cells	35
Role of the endocannabinoid system in gonadal development: Implications for endocrine disruption and reproductive toxicity	33
Reproductive and developmental safety of nirmatrelvir (PF-07321332), an oral SARS-CoV-2 Mpro inhibitor in animal models	31
Effect of Humanin and MOTS-c on ameliorating reproductive damage induced by prepubertal cyclophosphamide chemotherapy in male mice	27
MiR-193a-5p serves as an inhibitor in ovarian cancer cells through RAB11A	26
Deoxynivalenol exposure during pregnancy has adverse effects on placental structure and immunity in mice model	25
Risk assessment of dietary exposure to trace elements that are reproductive toxicants: Lead, molybdenum and nickel. The case study of Armenia	25
Developmental and reproduction toxicity of piperonyl butoxide part 1 developmental safety of piperonyl butoxide in the CD® (Sprague Dawley) rat	25
BPA disrupts meiosis I in oogonia by acting on pathways including cell cycle regulation, meiosis initiation and spindle assembly	24
Editorial Board	24
Surveys as a valid tool for assessing food safety knowledge amongst pregnant women in high-income countries: a rapid review	23
Delta-9-tetrahydrocannabinol increases vascular endothelial growth factor (VEGF) secretion through a cyclooxygenase-dependent mechanism in rat granulosa cells	22
Engineering a computable epiblast for in silico modeling of developmental toxicity	21
Maternal polychlorinated biphenyl 126 (PCB 126) exposure modulates offspring gut microbiota irrespective of diet and exercise	21
Occupational exposure limits for reproductive toxicants – A comparative analysis	20

Comment on “Maternal use of fluconazole and congenital malformations in the progeny: A meta-analysis of the literature”	20
Organochlorine pesticide dieldrin upregulate proximal promoter (PII) driven CYP19A1 gene expression and increases estrogen production in granulosa cells	20
Excessive fluoride induces ovarian function impairment by regulating levels of ferroptosis in fluorosis women and ovarian granulosa cells	20
Considerations for and against dosing rodent pups before 7 days of age in juvenile toxicology studies	20
Editorial Board	20
Role of retinoids in biology and toxicology	20
Interaction of alcohol & phosphatidic acid in maternal rat uterine artery function	19
Editorial Board	19
A dynamic in vitro developing testis model reflects structures and functions of testicular development in vivo	18
Editorial Board	18
Editorial Board	18
A special issue on emerging techniques in reproductive and developmental toxicology	18
Nutrition, food safety and human reproductive and developmental health	18
Editorial Board	17
Dietary exposure to an environmentally relevant phthalate mixture alters follicle dynamics, hormone levels, ovarian gene expression, and pituitary gene expression in female mice	17
Viral infections, vaccines and antiviral drugs in pregnancy and the development of the conceptus	17
Editorial Board	17
Bisphenol A analogues and metabolic syndrome in women with polycystic ovary syndrome	17
Scalable expansion of iPSC and their derivatives across multiple lineages	16
Potential protective effect of quercetin on the male reproductive system against exposure of Wistar rats to crude oil vapor: Genetic, biochemical, and histopathological evidence	16
Review of embryo-fetal developmental toxicity studies performed for pharmaceuticals approved by FDA in 2020 and 2021.	16
Classical toxicity endpoints in female rats are insensitive to the human endocrine disruptors diethylstilbestrol and ketoconazole	16
Trichloroethylene modifies energy metabolites in the amniotic fluid of Wistar rats	15
Cadmium triggers oxidative stress and mitochondrial injury mediated apoptosis in human extravillous trophoblast HTR-8/SVneo cells	15
Association between early oxidative DNA damage and iron status in women with gestational diabetes mellitus	15
The influence of lead exposure on male semen parameters: A systematic review and meta-analysis	15
Prenatal developmental toxicity studies on fumes from oxidised asphalt (OA) in the rat	15
Bisphenol analogs AF, S and F: Effects on functional characteristics of porcine granulosa cells	15
Exposure to di-isononyl phthalate during early pregnancy disrupts decidual angiogenesis and placental development in mice	14
Spirulina (Arthrospira maxima) mitigates the toxicity induced by a mixture of metal and NSAID in Xenopus laevis	14
The association between genital mycoplasma infection and spontaneous abortion: A systematic review and meta-analysis	14
The potential protective effect of melatonin and N-acetylcysteine alone and in combination on opioid-induced testicular dysfunction and degeneration in rat	14
Maternal cypermethrin exposure during perinatal period dysregulates gonadal steroidogenesis, gametogenesis and sperm epigenome in F1 rat offspring	14
Juvenile exposure and adult risk assessment with single versus repeated exposure of melphalan in the germ cells of male SD rat: Deciphering the molecular mechanisms	13
Endocrine, metabolic and apical effects of in utero and lactational exposure to non-dioxin-like 2,2′,3,4,4′,5,5′-heptachlorobiphenyl (PCB 180): A postnatal follow-up study in rats	13
Teratogenic and neuro-behavioural toxic effects of bisphenol A (BPA) and B (BPB) on Xenopus laevis development	13
Maternal oral exposure to low-dose BPA accelerates the onset of puberty by promoting prepubertal Kiss1 expression in the AVPV nucleus of female offspring	13
Perfluorooctane sulfonic acid modulates expression of placental steroidogenesis-associated genes and hormone levels in pregnant rats	13
Hormetic effects of a cannabinoid system component, 2-arachidonoyl glycerol, on cell viability and expression profile of growth factors in cultured mouse Sertoli cells: Friend or foe of male fertility	13
Early-life exposure to acephate inhibits sexual development and induces testicular and ovarian toxicity in mice	13
Reproductive and immune effects emerge at similar thresholds of PFHxS in deer mice	13
Subchronic intake of arsenic at environmentally relevant concentrations causes histological lesions and oxidative stress in the prostate of adult Wistar rats	12
Rapid identification of reproductive toxicants among environmental chemicals using an in vivo evaluation of gametogenesis in budding yeast Saccharomyces cerevisiae	12
A low dose of benzo(a)pyrene during prepuberty in male rats generated immediate oxidative stress in the testes and compromised steroidogenic enzymes/proteins	12
DNAJA1 regulates protein ubiquitination and is essential for spermatogenesis in the testes of mice and rats	12
Aflatoxin B1 exposure exacerbates chemokine receptor expression in the BTBR T+ Itpr3tf/J Mouse Model, unveiling insights into autism spectrum disorder: A focus on brain and spleen	12
Effects of DDT and DDE on placental cholinergic receptors	12
Lower malathion concentrations reduce testosterone biosynthesis by Leydig TM3 cells in vitro by altering cellular redox profile and inducing oxidative damage	12
Bisphenol A-induced polycystic ovary syndrome (PCOS) with hormonal and metabolic implications in rats	12
Potential dual protective effects of melatonin on spermatogonia against hexavalent chromium	11

Corrigendum to “Reproductive and developmental toxicity of perfluorooctane sulfonate (PFOS) in the white-footed mouse (Peromyscus leucopus)” [Reprod. Toxicol. 113 (2020) 120–127]	11
Elucidating the molecular interactions and immune modulation of bisphenols exposure in the pathogenesis of polycystic ovary syndrome	11
Editorial Board	11
Diuron-induced fetal Leydig cell dysfunction in in vitro organ cultured fetal testes	11
Developmental and reproduction toxicity of piperonyl butoxide part 2 developmental safety of piperonyl butoxide in the NZW rabbit	11
Long-term subculture induces syncytialization and influent the response to bisphenol A (BPA) of placental JEG-3 cells	11
Perfluorooctanoic acid promotes proliferation of the human granulosa cell line HGrC1 and alters expression of cell cycle genes and Hippo pathway effector YAP1	11
EIF3D promotes the progression of preeclampsia by inhibiting of MAPK/ERK1/2 pathway	11
Epidemiologically relevant phthalates affect human endometrial cells in vitro through cell specific gene expression changes related to the cytoskeleton and mitochondria	11
Whole mount preparation and analysis of rabbit mammary gland	11
Combined reproductive and developmental toxicity study of pesticide abamectin on male and female Wistar Hannover rats	11
Association between exposures to phthalate metabolites and preterm birth and spontaneous preterm birth: A systematic review and meta-analysis	10
Maternal exposure to phthalates and total gestational weight gain in the LIFECODES birth cohort	10
Shatavarin-IV rescues the Di (2-ethylhexyl) phthalate (DEHP) induced oxidative stress in rat granulosa cells in vitro	10
Transgenerational effects of bisphenol A on zebrafish reproductive tissues and sperm motility	10
Environmental basis for early onset breast cancer	10
Low levels of nicotine and cotinine but not benzo[a]pyrene induce human trophoblast cell proliferation	10
Gentisic acid attenuates 5-fluorouracil-induced ovotoxicity in rats via modulating Nrf2 signalling: An experimental approach	9
Epigallocatechin-3-gallate attenuates cyclophosphamide-induced damage in mouse ovarian tissue via suppressing inflammation, apoptosis, and expression of phosphorylated Akt, FOXO3a and rpS6	9
Vitamin D3 protects against lead-induced testicular toxicity by modulating Nrf2 and NF-κB genes expression in rat	9
Editorial Board	9
Extended one-generation reproductive toxicity study of food-grade titanium dioxide E171 with emphasis on reproductive and endocrine endpoints	9
Prostate as a target of endocrine disrupting chemicals: Relevance, pathways, assays	9
Advancing the use of new approach methodologies for assessing teratogenicity: Building a tiered approach	9
Lack of effects on female fertility and prenatal and postnatal offspring development in rats with BNT162b2, a mRNA-based COVID-19 vaccine	9
Exposure to phthalates and female reproductive health: A literature review	9
Best practices to quantify the impact of reproductive toxicants on development, function, and diseases of the rodent mammary gland	9
Effect of 1-nitropyrene exposure on the biological behavior of trophoblast cells	9
Antidepressant aripiprazole induces adverse effects on neural development during cortex organoid generation	9
Evaluation of temperature- and ethanol-related developmental degree variations by a new scoring system (FETAX-score) applicable to Frog Embryo Teratogenicity Assay: Xenopus	9
Ovarian toxicity of nanoparticles	9
Perfluorononanoic acid impedes mouse oocyte maturation by inducing mitochondrial dysfunction and oxidative stress	9
Developmental exposure to polycyclic aromatic hydrocarbons (PAHs): Focus on benzo[a]pyrene neurotoxicity	9
Arachidonic acid modulates the cellular energetics of human pluripotent stem cells and protects the embryoid bodies from embryotoxicity effects in vitro	9
Bisphenol A: Epigenetic effects on the male reproductive system and male offspring	9
Transcriptomic and proteomic features of a mouse model of sperm DNA damage induced by benzo(a)pyrene	8
Prenatal high-sucrose diet affects pulmonary artery contractile functions via MT receptors	8
Prevention and reversal of chlorpromazine induced testicular dysfunction in rats by synergistic testicle-active flavonoids, taurine and coenzyme-10	8
Critical appraisal of the expert knowledge elicitation (EKE) methodology to identify uncertainties in building cumulative assessment groups for craniofacial alterations	8
Neurocognitive impairments in rat offspring after maternal exposure to vortioxetine: Involvement of BDNF, apoptosis and cholinergic mediated signaling pathways	8
Developmental exposure to an environmentally relevant dose of Bisphenol S impairs postnatal growth and disrupts placental transcriptional profile in female rat	8
Erroneous statement	8
Oxidative stress and energy metabolism in male reproductive damage from single and combined high-power microwave exposure at 1.5 and 4.3GHz	8
Exploring the impact of environmental factors on male reproductive health through epigenetics	8
Maternal prenatal smoking and long-term gastrointestinal morbidity of the offspring: A population-based cohort analysis	8
Editorial Board	8
Inhibition of Sirtuin-1 hyperacetylates p53 and abrogates Sirtuin-1-p53 interaction in Cr(VI)-induced apoptosis in the ovary	8
Unravelling the epigenetic impact: Oxidative stress and its role in male infertility-associated sperm dysfunction	8
Reproductive findings in male animals exposed to selective survival of motor neuron 2 (SMN2) gene splicing-modifying agents	8
Alogliptin attenuates testicular damage induced by monosodium glutamate in both juvenile and adult male rats by activating autophagy: ROS dependent AMPK/mTOR	8
Endoderm and mesoderm derivatives in embryonic stem cell differentiation and their use in developmental toxicity testing	8
Investigations on the effects of in vitro exposure of mouse ovaries to withaferin A, a new candidate for chemotherapy	8
Vinorelbine administration impedes the timely progression of meiotic maturation and induces aneuploidy in mouse oocytes	8
Editorial Board	7
Parental exposure to 3-methylcholanthrene before gestation adversely affected the endocrine system and spermatogenesis in male F1 offspring	7
Editorial Board	7
Editorial Board	7
Prenatal exposure to an environmentally relevant phthalate mixture alters ovarian steroidogenesis and folliculogenesis in the F1 generation of adult female mice	7
Prenatal ethanol exposure induces dynamic changes of expression and activity of hepatic cytochrome P450 isoforms in male rat offspring	7
Inhibition of DNA methylation in newborns reprograms ischemia-sensitive biomarkers resulting in development of a heart ischemia-sensitive phenotype late in life	7
Comment on “Effects of the 2018 camp fire on birth outcomes in non-human primates: Case-control study”	7
Editorial Board	7
Development and validation of a machine-learning algorithm to predict the relevance of scientific articles within the field of teratology	7
Editorial Board	7
Carvacrol showed a curative effect on reproductive toxicity caused by Bisphenol AF via antioxidant, anti-inflammatory and anti-apoptotic properties	7
Causal association between 25-Hydroxyvitamin D and risk of abnormal spermatozoa: A bidirectional Mendelian randomization study	7
Toxicity assessments of selected trichloroethylene and perchloroethylene metabolites in three in vitro human placental models	7
Bisphenol A exposure advances puberty onset by changing Kiss1 expression firstly in arcuate nucleus at juvenile period in female rats	7
Associations between maternal mono-(2-ethylhexyl) phthalate levels, nuclear receptor gene polymorphisms, and fatty acid levels in pregnant Japanese women in the Hokkaido study	7
Determination of the panel of reference genes for quantitative real-time PCR in fetal and adult rat intestines	7
Decamethylcyclopentasiloxane developmental neurotoxicity testing	7
Anti-apoptotic effect of adrenomedullin gene delivery on Leydig cells by suppressing TGF-β1 via the Hippo signaling pathway	7
Metabolomic and transcriptomic responses of mouse testis to the dextran sulfate sodium induced colitis	7
Association between short-term exposure to particulate matter air pollution and outcomes of assisted reproduction technology in Lombardy, Italy: A retrospective cohort study	7
Assessment of sexual hormones in foundry workers exposed to heat stress and electromagnetic fields	7
Teratogenic effects of voriconazole (anti-fungal drug) on Swiss albino mice	6
Exploring the ameliorative potential of rutin against High-Sucrose Diet-induced oxidative stress and reproductive toxicity in Drosophila melanogaster	6
Hesperidin has a protective effect on paclitaxel-induced testicular toxicity through regulating oxidative stress, apoptosis, inflammation and endoplasmic reticulum stress	6
The effect of adipose-derived mesenchymal stem cell treatment on mTOR and p-mTOR expression in ovarian damage due to cyclophosphomide	6
Waves of follicle development, growth and degeneration in adult ovary of zebrafish (Danio rerio) on chronic exposure to environmental estrogens in laboratory	6

Bisphenol A exposure and thyroid dysfunction during pregnancy: A systematic review	6
Maternal exposure to perfluoroalkyl chemicals and anogenital distance in the offspring: A Faroese cohort study	6
Placental model as an important tool to study maternal-fetal interface	6
The mediating role of abnormal ZEB1 methylation in the association between nickel exposure and non-syndromic orofacial cleft	6
Cigarette smoke is associated with up-regulation of inducible NOS and COX-2 protein expression and activity in granulosa cells of women undergoing in vitro fertilization	6
Perspectives on chick embryo models in developmental and reproductive toxicity screening	6
High seminal BPA in IVF patients correlates with lower sperm count and up-regulated miR-21 and miR-130a	6
Prenatal alcohol exposure disrupts Sonic hedgehog pathway and primary cilia genes in the mouse neural tube	6
Determination of the zebrafish embryo developmental toxicity assessment (ZEDTA) as an alternative non-mammalian approach for the safety assessment of agrochemicals	6
Ethylene oxide suppresses boar sperm function during capacitation	6
Highly conserved sperm function-related transcripts across three species: human, rat and mouse	6
Neuropsychiatric outcomes in offspring after fetal exposure to maternal influenza infection during pregnancy: A systematic review	6
Genetic evidence linking retinol to birth weight: A two-sample Mendelian randomization study	6
Perfluorooctane sulfonate and perfluorooctanoic acid induce plasma membrane dysfunction in boar spermatozoa during in vitro capacitation	6
Melatonin and resveratrol alleviate molecular and metabolic toxicity induced by Bisphenol A in endometrial organoids	6
Editorial Board	6
In utero chronic intermittent nicotine aerosol exposure increases ischemic heart injury in adult offspring via programming of Angiotensin II receptor-derived TGFβ/ROS/Akt signaling pathway	6
Perfluorooctanoic acid suppresses sperm functions via abnormal Protein Kinase B activation during capacitation	6
Role of aryl hydrocarbon receptor (AHR) in overall retinoid metabolism: Response comparisons to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure between wild-type and AHR knockout mice	6