Reproductive Toxicology

Article	Citations
Editorial Board	153
Whole mount preparation and analysis of rabbit mammary gland	86
A low dose of benzo(a)pyrene during prepuberty in male rats generated immediate oxidative stress in the testes and compromised steroidogenic enzymes/proteins	66
RETRACTED: Overexpressed miR-106b-5p promotes epithelial-mesenchymal transition in endometriosis by targeting PTEN	52
Evaluation of reproductive toxicology studies according the OECD Guideline 443 – Claim and reality	47
Teratogenic and neuro-behavioural toxic effects of bisphenol A (BPA) and B (BPB) on Xenopus laevis development	47
Small extracellular vesicles derived from Nrf2-stimulated bone marrow mesenchymal stem cells ameliorated the testis damage and fertility disorder in doxorubicin-treated mice	45
Risk assessment of dietary exposure to trace elements that are reproductive toxicants: Lead, molybdenum and nickel. The case study of Armenia	42
Perfluorononanoic acid impedes mouse oocyte maturation by inducing mitochondrial dysfunction and oxidative stress	39
Bisphenol A-induced polycystic ovary syndrome (PCOS) with hormonal and metabolic implications in rats	38
Co-administration of atorvastatin with piperine induces reproductive toxicity in male Wistar rats through oxidative stress induction and downregulation of StAR, CYP11a1, 3βHSD and 17βHSD genes	37
Surveys as a valid tool for assessing food safety knowledge amongst pregnant women in high-income countries: a rapid review	34
EIF3D promotes the progression of preeclampsia by inhibiting of MAPK/ERK1/2 pathway	32
Extended one-generation reproductive toxicity study of food-grade titanium dioxide E171 with emphasis on reproductive and endocrine endpoints	31
Perfluorooctane sulfonic acid modulates expression of placental steroidogenesis-associated genes and hormone levels in pregnant rats	28
Epigallocatechin-3-gallate attenuates cyclophosphamide-induced damage in mouse ovarian tissue via suppressing inflammation, apoptosis, and expression of phosphorylated Akt, FOXO3a and rpS6	27
Ovarian toxicity of nanoparticles	27
Editorial Board	26
Editorial Board	26
Examination of piperonyl butoxide developmental toxicity as a Sonic hedgehog pathway inhibitor targeting limb and palate morphogenesis	25
Causal association between 25-Hydroxyvitamin D and risk of abnormal spermatozoa: A bidirectional Mendelian randomization study	25
Repeat-dose and embryo-fetal developmental toxicity of zinpentraxin alfa	25
Impact of fluoride exposure on reproductive health: Insights into molecular mechanisms and health implications	24
Teratogenicity and Reactive Oxygen Species after transient embryonic hypoxia: Experimental and clinical evidence with focus on drugs causing failed abortion in humans	24
Antidepressant aripiprazole induces adverse effects on neural development during cortex organoid generation	23

Mechanistic decoding of octyl methoxycinnamate-induced breast toxicity via network toxicology, mendelian randomization, and molecular simulations	23
Critical appraisal of the expert knowledge elicitation (EKE) methodology to identify uncertainties in building cumulative assessment groups for craniofacial alterations	22
Induced-damages on preantral follicles by withanolide D, a potent chemotherapy candidate are not attenuated by melatonin	22
Teratogenic effects of voriconazole (anti-fungal drug) on Swiss albino mice	22
Prenatal exposure to the phthalate DEHP impacts reproduction-related gene expression in the pituitary	21
Developmental exposure to an environmentally relevant dose of Bisphenol S impairs postnatal growth and disrupts placental transcriptional profile in female rat	21
2,4-dichlorophenoxyacetic acid (2,4-D) exposure during postnatal development alters the effects of western diet on mouse prostate	20
Bisphenol A exposure advances puberty onset by changing Kiss1 expression firstly in arcuate nucleus at juvenile period in female rats	20
Perfluorooctane sulfonate and perfluorooctanoic acid induce plasma membrane dysfunction in boar spermatozoa during in vitro capacitation	20
Quality criteria for in vitro human pluripotent stem cell-derived models of tissue-based cells	20
Prostate as a target of endocrine disrupting chemicals: Relevance, pathways, assays	20
Comment on “Effects of the 2018 camp fire on birth outcomes in non-human primates: Case-control study”	20
Long-term transplantation human menstrual blood mesenchymal stem cell loaded collagen scaffolds repair endometrium histological injury	19
Hesperidin has a protective effect on paclitaxel-induced testicular toxicity through regulating oxidative stress, apoptosis, inflammation and endoplasmic reticulum stress	18
Fenoxaprop-P-ethyl herbicide induces biochemical, histopathological, and immunohistochemical alterations in the kidneys and testes of rats	18
Biological variability hampers the use of skeletal staining methods in zebrafish embryo developmental toxicity assays	18
Cigarette smoke is associated with up-regulation of inducible NOS and COX-2 protein expression and activity in granulosa cells of women undergoing in vitro fertilization	18
Prenatal alcohol exposure disrupts Sonic hedgehog pathway and primary cilia genes in the mouse neural tube	18
Toxicity from a single injection of human umbilical cord mesenchymal stem cells into rat ovaries	17
Editorial Board	17
Exposure to brominated flame retardants during pregnancy and lactation increases the prevalence of breast lesions and cancer-associated pathways in sprague-dawley rats	17
Effect of Lactobacillus plantarum on folliculogenesis in deep frying oil-fed rats	17
Isoliquiritigenin ameliorates paroxetine-induced sexual dysfunction in male albino mice	16
Extended one generation reproductive toxicity study and effect on gut flora of genetically modified rice rich in β-carotene in wistar rats	16
The potential of mechanistic information organised within the AOP framework to increase regulatory uptake of the developmental neurotoxicity (DNT) in vitro battery of assays	16
Adverse Effects of Avobenzone on Boar Sperm Function: Disruption of Protein Kinase A Activity and Tyrosine Phosphorylation	16
Contribution of ferritin and zinc to adverse infant outcomes among pregnancies with prenatal alcohol exposure in South Africa	16
Maternal trichloroethylene exposure and metabolic gene polymorphisms may interact during fetal cardiovascular malformation	16
Evaluation of cytoprotective effects of cannabidiol on neuroinflammation and neurogenesis process in rat offsprings	15
Effect of prenatal exposure to phthalates on birth weight of offspring: A meta-analysis	15
Single cell RNA sequencing techniques and applications in research of ovary development and related diseases	15
The mechanisms of tripterygium glycosides-induced reproductive toxicity and detoxification strategies	15
Effects of di-(2-ethylhexyl) terephthalate on hypothalamus-pituitary-gonad axis in adult zebrafish	15
Effects of chronic CuNPs treatment followed by termination for two spermatogenic cycles in the testicular functions of mice	15
Quaternary ammonium compound exposure causes infertility by altering endocrine signaling and gametogenesis	15
Episodic ozone exposure in Long-Evans rats has limited effects on cauda sperm motility and non-coding RNA populations	15
Ascorbic acid modulates testicular toxicity of Ampligo® 150 ZC insecticide in male rabbit (Oryctolagus cuniculus)	15
Current knowledge, challenges, new perspectives of the study, and treatments of Autism Spectrum Disorder	14
Psychosocial stress and associations with inflammation in mid-gestation maternal, fetal, and placental tissue	14
Embryotoxicity of statins and other prescribed drugs with reported off-target effects on cholesterol biosynthesis	14
Maternal chronic caffeine intake impairs fertility, placental vascularization and fetal development in mice	14
Molecular mechanisms associated with embryotoxic effects of heavy metals in the Sea Urchin	14
Disruption of fetal eye development caused by insulin-induced maternal hypoglycemia in rats	14
The impact of isotretinoin on the pituitary-ovarian axis: An interpretative review of the literature	14
Impact of Bisphenol A exposure on maternal gut microbial homeostasis, placental function, and fetal development during pregnancy	14
Trichlorfon blocks androgen synthesis and metabolism in rat immature Leydig cells	14
Exposure to ethinyl estradiol during lactation reduces maternal mammary gland complexity and restricts pup growth in mice	14
Folate in maternal rheumatoid arthritis-filial autism spectrum disorder continuum	14
Impacts of heavy metal exposure on the prostate of murine models: Mechanisms of toxicity	13
Subacute high-refined carbohydrate diet leads to abnormal reproductive control of the hypothalamic-pituitary axis in female rats	13

Immunogenicity-related placental infarcts and abortions in nonhuman primate developmental and reproductive toxicity studies: Proposed mechanism and impact on study interpretation	13
Association between polycyclic aromatic hydrocarbons and infertility in U.S. women: National Health and Nutrition Examination Survey 2013–2016	13
Association between dietary intake estimated levels of PCDD/Fs and human sperm quality	13
Cadmium exposure causes trophoblast abnormal syncytization and endocrine dysfunction in preeclampsia	13
Zebrafish embryos as a teratogenicity screening tool to reduce potential birth defects	13
Safety of lactational exposure to venlafaxine on the rat mammary gland development and carcinogenesis in F1 female offspring	13
Maternal 129S1/SvImJ background attenuates the placental phenotypes induced by chronic paternal alcohol exposure	13
Effects of a TAML catalyst on mice exposed during pregnancy and lactation	13
Subcutaneous zilucoplan: Evaluation of reproductive toxicology	12
Neurotensin receptor-1 antagonist SR48692 modulation of high-fat diet induced reproductive impairment in male mice	12
Zearalenone interferes with the sperm-triggered inflammation in the bovine uterus in vitro: Negative impact on sperm motility and survival	12
Fish oil supplementation protects against protein undernutrition-induced testicular and ovarian biochemical alterations in rats	12
Placental BCRP transporter reduces cadmium accumulation and toxicity in immortalized human trophoblasts	12
Associations between urinary and follicular fluid concentrations of phthalate metabolites and reproductive outcomes in Brazilian women undergoing fertility treatment	12
Comprehensive digital documentation of teratology studies	12
Maternal preconception and pregnancy tobacco and cannabis use in relation to placental developmental markers: A population-based study	12
The effects of exposure to microplastics on female reproductive health and pregnancy outcomes: A systematic review and meta-analysis	12
Air pollution-linked epigenetic modifications in placental DNA: Prognostic potential for identifying future foetal anomalies	12
Effects of perinatal exposures to a TAML catalyst on the mammary gland and hormone-sensitive outcomes in male mice	12
AOP key event relationship report: Linking decreased androgen receptor activation with decreased granulosa cell proliferation of gonadotropin-independent follicles	11
Protocatechualdehyde improves cyclophosphamide-induced premature ovarian insufficiency by inhibiting granulosa cell apoptosis and senescence through the SIRT1/p53 axis	11
Exposure to Di-2-ethylhexyl phthalate (DEHP) and infertility in women, NHANES 2013-2016	11
Potential dual protective effects of melatonin on spermatogonia against hexavalent chromium	11
Impact of endocrine disruptors from mother's diet on immuno-hormonal orchestration of brain development and introduction of the virtual human twin tool	11
Potential protective effect of beta-caryophyllene against cadmium chloride-induced damage to the male reproductive system in mouse	11
DNA methylation in polycystic ovary syndrome: Emerging evidence and challenges	11
Independent and interactive effects of air pollutants and ambient heat exposure on congenital heart defects	11
Prenatal caffeine consumption and neurobehavioral disorders - A systematic review	11
Propylparaben negatively impacts IN VITRO preimplantation mouse embryo development	11
Xeno-estrogenic activity of real-life mixtures of perfluoroalkylated substances in human placenta homogenates	11
Protective role of hesperidin in finasteride-induced testicular toxicity in adult male Wistar rats: Insights into oxidative stress, apoptosis, and ultrastructure of seminiferous tubules	11
Editorial Board	11
Respiratory exposure to carbon black nanoparticles may induce testicular structure damage and lead to decreased sperm quality in mice	11
Diuron-induced fetal Leydig cell dysfunction in in vitro organ cultured fetal testes	10
Exposure to di-isononyl phthalate during early pregnancy disrupts decidual angiogenesis and placental development in mice	10
Bisphenol A analogues and metabolic syndrome in women with polycystic ovary syndrome	10
A dynamic in vitro developing testis model reflects structures and functions of testicular development in vivo	10
Advancing the use of new approach methodologies for assessing teratogenicity: Building a tiered approach	10
Considerations for and against dosing rodent pups before 7 days of age in juvenile toxicology studies	10
Low levels of nicotine and cotinine but not benzo[a]pyrene induce human trophoblast cell proliferation	10
Editorial Board	10
Mechanisms underlying impaired spermatogenic function in orchitis induced by busulfan	10
Transgenerational effects of bisphenol A on zebrafish reproductive tissues and sperm motility	10
Effects of DDT and DDE on placental cholinergic receptors	10
Shatavarin-IV rescues the Di (2-ethylhexyl) phthalate (DEHP) induced oxidative stress in rat granulosa cells in vitro	10
Bisphenol analogs AF, S and F: Effects on functional characteristics of porcine granulosa cells	10
The influence of lead exposure on male semen parameters: A systematic review and meta-analysis	10
Editorial Board	9
The mediating role of abnormal ZEB1 methylation in the association between nickel exposure and non-syndromic orofacial cleft	9
Intergenerational effects of the antioxidant Idebenone on the placentas of rats with gestational diabetes mellitus	9
Editorial Board	9
Prolonged exposure to rosuvastatin from pre-puberty to adulthood impairs sperm quality in mice and leads to paternally mediated developmental toxicity	9
Editorial Board	9
The effect of adipose-derived mesenchymal stem cell treatment on mTOR and p-mTOR expression in ovarian damage due to cyclophosphomide	9
Prenatal and postnatal exposure to polychlorinated biphenyls alter follicle numbers, gene expression, and a proliferation marker in the rat ovary	9
Independent and interaction effects of prenatal exposure to high AQI and extreme Humidex on the risk of preterm birth: A large sample population study in northern China	9
Editorial Board	9
Erroneous statement	9
In vivo pharmacokinetic analyses of placental transfer of three drugs of different physicochemical properties in pregnant rats	9
Biological sex differences in hepatic response to in utero dimethylbenz(a)anthracene exposure	9
Neuropsychiatric outcomes in offspring after fetal exposure to maternal influenza infection during pregnancy: A systematic review	9
Vulnerable periods for the mouse mammary gland: Comparison of the effects of ethinyl estradiol exposures during two early stages of development	8
Effect of 1-nitropyrene exposure on the biological behavior of trophoblast cells	8
An analysis of birth defects and developmental disabilities for children of participants of the Air Force Health Study	8
Subacute tributyltin exposure alters the development and morphology of mammary glands in association with CYP19A1 expression in female rats	8
Screening for chemicals with thyroid hormone-disrupting effects using zebrafish embryo	8
Transcriptional profiling of Chinese hamster ovary (CHO) cells exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)	8
The fate of bisphenol A, bisphenol S, and their respective glucuronide metabolites in ovarian cells	8
Ulipristal (UPA) effects on rat ovaries: Unraveling follicle dynamics, ovulation inhibition, and safety implications for prolonged use	8
Prenatal high-sucrose diet affects pulmonary artery contractile functions via MT receptors	8
Effects of oridonin on sperm function and the PI3K/PDK1/AKT signaling pathway: Implications for reproductive toxicity	8
Editorial Board	8
Sucralose triggers insulin resistance leading to follicular dysplasia in mice	8
Exposure to Valproic acid (VPA) resulted in alterations in the expression of angiogenic genes (NRP-1, VEGFA, VEGFR-2 and sFlt1) and histological modifications in the placenta of mice (Mus musculus)	8
Phthalates and polycystic ovary syndrome – Systematic literature review	8
New approach methodologies to confirm developmental toxicity of pharmaceuticals based on weight of evidence	8
Synthetic human gonadal tissues for toxicology	8
Development of a microfluidic system structured on a modified polydimethylsiloxane device for the selection of bovine epididymal spermatozoa	8
Alkali and alkaline earth elements in maternal serum and occurrence of orofacial clefts in offspring	8
Association between menopausal age and smoking status defined using urinary cotinine or tobacco-specific nitrosamine metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol: The Korea National Health	8

Role of Rab proteins in PFOA-induced changes in boar sperm motility and capacitation	8
Corrigendum to “Peroxisome proliferator activated receptor gamma (PPAR-γ) ligand pioglitazone regulated gene networks in term human primary trophoblast cells” [Reprod. Toxicol. 81 (2018) 99–107]	7
Upscaling biological complexity to boost neuronal and oligodendroglia maturation and improve in vitro developmental neurotoxicity (DNT) evaluation	7
Nicotinamide mononucleotide enhances the developmental potential of mouse early embryos exposed to perfluorooctanoic acid	7
Use of leflunomide among girls and women of childbearing age and occurrence of leflunomide-exposed pregnancies in Germany	7
Lack of direct bone effect of tofacitinib, a JAK inhibitor, in juvenile rats and evaluation of the association between offspring growth and femur length	7
Bisphenol M inhibits mouse oocyte maturation in vitro by disrupting cytoskeleton architecture and cell cycle processes	7
Ampligo® 150 ZC affect the expression of sex hormone receptors and cell proliferation marker in female rabbit ovary: Protective effects of thyme essential oil and vitamin C	7
Effectiveness of Withania frutescens root extract on testicular damage induced by lead acetate in adult albino rats	7
Smoking during pregnancy is associated with the placental proteome	7
Impact of the environmental endocrine disruptor flutamide on cryptorchidism: Molecular mechanisms involving connexin-43 and p38-MAPK signaling	7
The associations between prenatal plastic phthalate exposure and lipid acylcarnitine levels in humans and mice	7
Pubertal sexual development and endpoints for disrupted spermatogenesis in the model Xenopus tropicalis	7
1-(N-methyl-N-nitrosamino)-1-(3-pyridinyl)-4-butanal exposure induces testicular toxicity in male mice	7
Editorial Board	7
Metal(loid)s and human semen quality: The LIFE Study	7
Subacute exposure to a mixture of tributyltin plus mercury impairs reproductive axis function, exacerbating premature ovarian insufficiency features and reducing fertility in female rats	7
Endocrine disruptors and endometriosis	7
Ultra-diluted/dynamized doxorubicin reduces the toxicity caused by doxorubicin during the in vitro culture of pig preantral follicles enclosed in ovarian tissue	7
Blastocyst exposure to plastic during mice in vitro fertilization impacts placental development	7
Effect of ofatumumab on pregnancy, parturition, and lactation in cynomolgus monkeys	7
Identification of endocrine disrupting chemicals targeting NTD-related hub genes during pregnancy via in silico analysis	7
Evaluation of the maternal and developmental toxicity of 6-methylmercaptopurine riboside in rats	7
Hormonal mechanism and pathogenetic therapy of citalopram-induced infertility in female rats	7