OOIR: Observatory of International Research

Papers

(The H4-Index of Genes & Development is 34. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
ZFP451-mediated SUMOylation of SATB2 drives embryonic stem cell differentiation	327
Three-layered control of mRNA poly(A) tail synthesis in Saccharomyces cerevisiae	164
A nonneural miRNA cluster mediates hearing via repression of two neural targets	120
Tnpo3 enables EBF1 function in conditions of antagonistic Notch signaling	115
A novel pathogenic mutation of MeCP2 impairs chromatin association independent of protein levels	110
ALL-tRNAseq enables robust tRNA profiling in tissue samples	88
The SpoVA membrane complex is required for dipicolinic acid import during sporulation and export during germination	85
NDF is a transcription factor that stimulates elongation by RNA polymerase II	84
RNA biogenesis and RNA metabolism factors as R-loop suppressors: a hidden role in genome integrity	67
Molecular basis of mRNA transport by a kinesin-1–atypical tropomyosin complex	66
RUNX1 is required in granulocyte–monocyte progenitors to attenuate inflammatory cytokine production by neutrophils	60
WDR5 represents a therapeutically exploitable target for cancer stem cells in glioblastoma	58
How do genomes encode developmental time?	53
Corrigendum: Hierarchical reactivation of transcription during mitosis-to-G1 transition by Brn2 and Ascl1 in neural stem cells	52
The evolving tale of Pol2 function	50
Cohesin in 3D: development, differentiation, and disease	49
Oct4 redox sensitivity potentiates reprogramming and differentiation	48
Notch induces transcription by stimulating release of paused RNA polymerase II	47
Metabolic partitioning in the brain and its hijacking by glioblastoma	43
CDK4loss-of-function mutations cause microcephaly and short stature	42
The biological underpinnings of therapeutic resistance in pancreatic cancer	42
RNA Pol II pausing facilitates phased pluripotency transitions by buffering transcription	42
Systematic functional characterization of antisense eRNA of protocadherin α composite enhancer	42
Minding the message: tactics controlling RNA decay, modification, and translation in virus-infected cells	42
Recognition of acetylated histone by Yaf9 regulates metabolic cycling of transcription initiation and chromatin regulatory factors	42

Letters to the Editor	41
USP7 substrates identified by proteomics analysis reveal the specificity of USP7	39
Rap1 regulates TIP60 function during fate transition between two-cell-like and pluripotent states	38
The evolution of metazoan shelterin	38
Histone bivalency regulates the timing of cerebellar granule cell development	37
Two unrelated distal genes activated by a shared enhancer benefit from localizing inside the same small topological domain	37
Unraveling the complexity of thermogenic remodeling of white fat reveals potential antiobesity therapies	36
Tolerance thresholds underlie responses to DNA damage during germline development	35
Proteomic insights into circadian transcription regulation: novel E-box interactors revealed by proximity labeling	35
Corrigendum: Identification of a PTEN-regulated STAT₃brain tumor suppressor pathway	34
Opening the window for endothelial-to-hematopoietic transition	34