OOIR: Observatory of International Research

Papers

(The H4-Index of Free Radical Biology and Medicine is 59. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Human 3D full skin models coupled with advanced bio-markers assessment for the efficacy evaluation of topical redox modulators	254
The use of systems biology in treatment of metabolic diseases	227
Peroxiporins: can they modulate cancer resistance?	213
The Relationship between Mitochondrial Oxidative Stress and Huntington’s Disease Progression	207
Oxidative damage in reperfusion after stroke: ferroptosis and the role of the mitochondrial sodium/calcium exchanger NCLX	178
Editorial Board	178
Exploring the non-toxic therapeutic potential of dioscorea communis in combating oral pathogenic bacteria and their effect on hard and soft oral tissues	173
Characterization of immunogenic MDA-lipidperoxidation epitopes on human plasma extracellular vesicles recognized by a human monoclonal IGM-antibody	169
Lipid-derived electrophiles induce carbonyl stress, mitochondrial dysfunction, and cellular senescence: 4-hydroxynonenal as a physiological determinant of adipose senescence in obesity and aging	159
A comprehensive LC-MS/MS approach for the monitoring of oxidative stress markers in gingival samples	147
Short-term blockade of E-prostanoid 3 receptor curbs necroinflammation and protects against I/R- and doxorubicin-induced acute myocardial injury	135
GSNOR drives age-related obesity by regulating the S-nitrosation of Beclin-1 to promote adipose tissue whitening	133
Fluorescence imaging for the progression of oxidative stress-related diseases	124
Redox resilience in hypoxia-tolerant Tenebrio molitor larvae	118
Calcineurin/NFAT1/Smad2 signaling regulates microglial autophagy that contributes to neuroinflammation and cognitive deficit in mice with sepsis-associated encephalopathy	117
Mouse models used to test the role of reactive oxygen species in aging and age-related chronic diseases	115
Role of Coenzyme Q10 in mitochondrial dysfunction and oxidative damage in RETT syndrome	110
Effect of Thermal Processing and Oxygen concentration on the Phenolic Composition and Inhibition of Advanced Glycation End Products of Chilean Beans (Phaseolus vulgaris) Extracts	107
Spatial transcriptomic profiling and selenoprotein expression in mouse brain following glucocorticoid administration	106
E2/E3-independent ubiquitin-like protein conjugation by Urm1 is coupled to cysteine persulfidation and protects the proteome under oxidative stress	103
Crowding modulates the oxidant-induced cross-linking and aggregation of the key glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase	103
Constitutive activation of NLRP3 inflammasome machinery in ex-vivo models of Rett syndrome: from pathogenetic role to new potential therapeutic target	96
Metabolic Adaptations to Stress and Senescence in the Epidermis	94
Oxidation and chlorination of human amylin induces chemical and structural changes and formation of immunogenic products	94
Analysis of a planar catechin analog on cancer cellular inhibition	94

L-2-hydroxyglutaric Acid Intracerebroventricular Administration to Neonatal Rats Promotes Disturbance of Redox Homeostasis, Neuronal Death, Glial Reactivity and Delayed Myelination	93
Nitrogen Oxide-derived Anti-inflammatory Lipid Signaling Mediators	93
H3.1Cys96 oxidation promotes H3 variant exchange, chromatin remodeling, and breast cancer cell phenotypic plasticity	92
Hypochlorous acid-mediated modification of proteins and its consequences	90
The role of nitric oxide in autism spectrum disorder	90
Quantitative imaging of signaling with genetically encoded biosensors to study signaling in plants, yeast, and human cells	86
Increased intracellular persulfide levels attenuate HlyU-mediated hemolysin transcriptional activation in Vibrio cholerae	82
Alterations In Redox Homeostasis And Mitochondrial Dynamics In Liver Of MPS II Mice	78
NoxO1 and Erbin - a cooperation to control EGF signaling in cancer ?	76
Green Tea Polyphenols Protect against Genotoxic Damage and Modulate Endogenous Antioxidant Defenses in Hsd:ICR Mice Exposed to Hexavalent Chromium	76
AKR1A1 controls redox and metabolic adaptation of renal and hepatocellular carcinoma	75
Dynamics of plasma membrane repair upon oxidative damage	74
Selective inhibition of GSK3? mediates an Nrf2-independent anti-inflammatory microglial response	73
Hydrogen peroxide diffusion across human red blood cell membranes is not facilitated by aquaporins	73
Impaired Metabolic and Inflammatory Responses in a Murine Model of Leigh Syndrome	70
Arachidonic acid-derived lipoxin A4 yields an electrophilic 15-oxo metabolite that induces anti-inflammatory responses independent of FPR2 receptor signaling	70
Site-Specific Tyrosine Nitration of Heat Shock Protein 90 Plays Distinct Roles in Glioblastoma Multiforme	69
Shielding of Phospholipid Oxidation by 5,7-unsaturated Sterol Metabolites	67
Antiproliferative Effect of Novel Phenolic Antioxidant TS-13 in vitro	67
Heme nitrosyl complexes: insights into protein/protein transfer and cell trafficking	67
The stability and degradation products of polyhydroxy flavonols in boiling water	67
Characterization of human mitochondrial aconitase and its interaction with frataxin	66
Endothelial cells derived from elephant seals respond to extended hypoxia by suppressing inflammation and conserving glutathione	66
Adjunctive effects with continual X-ray irradiation for effective photodynamic therapy	65
Synthesis and Applications of Metal Organic Frameworks in Photodynamic Therapy	64
7-Dehydrocholesterol protects membrane phospholipids from oxidation	64
Regulation of ERK1/2 Phosphorylation, Oxidation, and Cell Cycle Progression by Miro1 Mediated Mitochondrial Positioning	63
Extracellular Superoxide Dismutase Regulation of Metabolism and Oxidative Stress in Pulmonary Artery Smooth Muscle Cells	63
Oxidative Stress Is Higher In Women With Sarcopenic Obesity	62
Radiation-induced Glioblastoma Extracellular Vesicles Containing 4HNE Promote Microglia-Mediated Neurotoxicity	62
ANG secretion predisposes endothelial cells toward angiogenesis in FIN56-induced ferroptotic hepatocellular carcinoma via the BMP6/ID1 signaling pathway	61
A Role for NRF2 in the Lung Epithelial Cell Response to Wood Smoke	61
miRNAome-metabolome wide association study reveals effects of miRNA regulation in male diabetic erectile dysfunction	60
Isotope-labeled ergothioneine clarifies the mechanism of reaction with singlet oxygen	60
Cigarette smoke induces pulmonary arterial dysfunction through an imbalance in the redox status of the soluble guanylyl cyclase	59
Inducible and reversible SOD2 knockdown in mouse skeletal muscle drives impaired pyruvate oxidation and reduced metabolic flexibility	59
SERCA2 dysfunction triggers hypertension by interrupting mitochondrial homeostasis and provoking oxidative stress	59