Free Radical Biology and Medicine

Papers
(The TQCC of Free Radical Biology and Medicine is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)
ArticleCitations
Human 3D full skin models coupled with advanced bio-markers assessment for the efficacy evaluation of topical redox modulators254
The use of systems biology in treatment of metabolic diseases227
Peroxiporins: can they modulate cancer resistance?213
The Relationship between Mitochondrial Oxidative Stress and Huntington’s Disease Progression207
Editorial Board178
Oxidative damage in reperfusion after stroke: ferroptosis and the role of the mitochondrial sodium/calcium exchanger NCLX178
Exploring the non-toxic therapeutic potential of dioscorea communis in combating oral pathogenic bacteria and their effect on hard and soft oral tissues173
Characterization of immunogenic MDA-lipidperoxidation epitopes on human plasma extracellular vesicles recognized by a human monoclonal IGM-antibody169
Lipid-derived electrophiles induce carbonyl stress, mitochondrial dysfunction, and cellular senescence: 4-hydroxynonenal as a physiological determinant of adipose senescence in obesity and aging159
A comprehensive LC-MS/MS approach for the monitoring of oxidative stress markers in gingival samples147
Short-term blockade of E-prostanoid 3 receptor curbs necroinflammation and protects against I/R- and doxorubicin-induced acute myocardial injury135
GSNOR drives age-related obesity by regulating the S-nitrosation of Beclin-1 to promote adipose tissue whitening133
Fluorescence imaging for the progression of oxidative stress-related diseases124
Redox resilience in hypoxia-tolerant Tenebrio molitor larvae118
Calcineurin/NFAT1/Smad2 signaling regulates microglial autophagy that contributes to neuroinflammation and cognitive deficit in mice with sepsis-associated encephalopathy117
Mouse models used to test the role of reactive oxygen species in aging and age-related chronic diseases115
Role of Coenzyme Q10 in mitochondrial dysfunction and oxidative damage in RETT syndrome110
Effect of Thermal Processing and Oxygen concentration on the Phenolic Composition and Inhibition of Advanced Glycation End Products of Chilean Beans (Phaseolus vulgaris) Extracts107
Spatial transcriptomic profiling and selenoprotein expression in mouse brain following glucocorticoid administration106
Crowding modulates the oxidant-induced cross-linking and aggregation of the key glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase103
E2/E3-independent ubiquitin-like protein conjugation by Urm1 is coupled to cysteine persulfidation and protects the proteome under oxidative stress103
Constitutive activation of NLRP3 inflammasome machinery in ex-vivo models of Rett syndrome: from pathogenetic role to new potential therapeutic target96
Oxidation and chlorination of human amylin induces chemical and structural changes and formation of immunogenic products94
Analysis of a planar catechin analog on cancer cellular inhibition94
Metabolic Adaptations to Stress and Senescence in the Epidermis94
Nitrogen Oxide-derived Anti-inflammatory Lipid Signaling Mediators93
L-2-hydroxyglutaric Acid Intracerebroventricular Administration to Neonatal Rats Promotes Disturbance of Redox Homeostasis, Neuronal Death, Glial Reactivity and Delayed Myelination93
H3.1Cys96 oxidation promotes H3 variant exchange, chromatin remodeling, and breast cancer cell phenotypic plasticity92
The role of nitric oxide in autism spectrum disorder90
Hypochlorous acid-mediated modification of proteins and its consequences90
Quantitative imaging of signaling with genetically encoded biosensors to study signaling in plants, yeast, and human cells86
Increased intracellular persulfide levels attenuate HlyU-mediated hemolysin transcriptional activation in Vibrio cholerae82
Alterations In Redox Homeostasis And Mitochondrial Dynamics In Liver Of MPS II Mice78
NoxO1 and Erbin - a cooperation to control EGF signaling in cancer ?76
Green Tea Polyphenols Protect against Genotoxic Damage and Modulate Endogenous Antioxidant Defenses in Hsd:ICR Mice Exposed to Hexavalent Chromium76
AKR1A1 controls redox and metabolic adaptation of renal and hepatocellular carcinoma75
Dynamics of plasma membrane repair upon oxidative damage74
Selective inhibition of GSK3? mediates an Nrf2-independent anti-inflammatory microglial response73
Hydrogen peroxide diffusion across human red blood cell membranes is not facilitated by aquaporins73
Arachidonic acid-derived lipoxin A4 yields an electrophilic 15-oxo metabolite that induces anti-inflammatory responses independent of FPR2 receptor signaling70
Impaired Metabolic and Inflammatory Responses in a Murine Model of Leigh Syndrome70
Site-Specific Tyrosine Nitration of Heat Shock Protein 90 Plays Distinct Roles in Glioblastoma Multiforme69
Heme nitrosyl complexes: insights into protein/protein transfer and cell trafficking67
The stability and degradation products of polyhydroxy flavonols in boiling water67
Shielding of Phospholipid Oxidation by 5,7-unsaturated Sterol Metabolites67
Antiproliferative Effect of Novel Phenolic Antioxidant TS-13 in vitro67
Characterization of human mitochondrial aconitase and its interaction with frataxin66
Endothelial cells derived from elephant seals respond to extended hypoxia by suppressing inflammation and conserving glutathione66
Adjunctive effects with continual X-ray irradiation for effective photodynamic therapy65
Synthesis and Applications of Metal Organic Frameworks in Photodynamic Therapy64
7-Dehydrocholesterol protects membrane phospholipids from oxidation64
Extracellular Superoxide Dismutase Regulation of Metabolism and Oxidative Stress in Pulmonary Artery Smooth Muscle Cells63
Regulation of ERK1/2 Phosphorylation, Oxidation, and Cell Cycle Progression by Miro1 Mediated Mitochondrial Positioning63
Radiation-induced Glioblastoma Extracellular Vesicles Containing 4HNE Promote Microglia-Mediated Neurotoxicity62
Oxidative Stress Is Higher In Women With Sarcopenic Obesity62
ANG secretion predisposes endothelial cells toward angiogenesis in FIN56-induced ferroptotic hepatocellular carcinoma via the BMP6/ID1 signaling pathway61
A Role for NRF2 in the Lung Epithelial Cell Response to Wood Smoke61
Isotope-labeled ergothioneine clarifies the mechanism of reaction with singlet oxygen60
miRNAome-metabolome wide association study reveals effects of miRNA regulation in male diabetic erectile dysfunction60
Inducible and reversible SOD2 knockdown in mouse skeletal muscle drives impaired pyruvate oxidation and reduced metabolic flexibility59
SERCA2 dysfunction triggers hypertension by interrupting mitochondrial homeostasis and provoking oxidative stress59
Cigarette smoke induces pulmonary arterial dysfunction through an imbalance in the redox status of the soluble guanylyl cyclase59
Investigation of Nrf2-Keap-1 and Sestrin-2 Pathways in Hidradenitis Suppurativa Patient Sera58
The nitrone compound LQB122 improves adipogenesis and reduces obesity-associated metabolic risk57
Extracellular Superoxide Dismutase R213G Variant Protects Against Lung Fibrosis by Activating AMPK and Limiting Lipid Accumulation57
Cu Transport Proteins as Novel Therapeutic Targets for Cu-dependent Brain Endothelial Barrier Dysfunction and Cuproptosis linked to Alzheimer’s Disease57
Effect OF m-trifluoromethyl- attachment on the glutathione peroxidase mimicry and antioxidant actions of diphenyl diselenide: Essential thiols of electrogenic sodium pump as a mechanistic componen57
Antioxidants Fail to Prevent Glucose Hypometabolism-Induced Neural Cell Death, Unlike Dimethyl-2-oxoglutarate: Implications in Alzheimer’s Disease57
PIDD1 and p90RSK Mediate Radiation-Induced Genomic Instability in Endothelial Cells: Implications for Cardiovascular Disease Prevention56
Breath Biomarkers for Monitoring In Vivo Redox Metabolism56
A neutralizing antibody and a p75NTR inhibitor prevent neuronal apoptosis induced by oxidatively modified NGF55
Intracellular and extracellular redox signals during exercise and aging54
Enzyme activated fluorescent probe for Vanin-1 multi-dimensional Imaging: Advanced insights for diagnosis and treatment of inflammatory bowel disease54
Therapeutic potential of plasma-treated solutions in atopic dermatitis54
Liposomal Encapsulation Augments Kaempferol-induced Apoptosis in Glioblastoma cells via a Pro-oxidation Pathway54
Hinokitiol modulates Nrf2/HO-1 signaling, autophagy, and URAT1 in hyperuricemia and oxidative stress models of renal injury54
Analysis of the inhibitory activity using computer-engineered peptides upon the enzyme protein disulfide isomerase (PDI): A Molecular Docking Study with Bean Peptides53
Hepatic IκBζ promotes alcohol-associated liver disease and acute hepatitis by enhancing CXCL1-Mediated neutrophil infiltration53
Effects of tobacco nitrate content on free radical levels in mainstream smoke53
Effect of melatonin on oxidative stress indicators in animal models of fibrosis: A systematic review and meta-analysis53
Inhibition of MAGL ameliorates glucocorticoid-induced bone loss by regulating the Nrf2 signaling53
Corrigendum to “Melatonin alleviates early brain injury by inhibiting the NRF2-mediated ferroptosis pathway after subarachnoid hemorrhage” [Free Radic. Biol. Med. 208 (2023) 555–570]53
Bioavailability of mango (poly)phenols: An evaluation of the impact of the colon, and phenylalanine and tyrosine on the production of phenolic catabolites52
Iron and atherosclerosis: Lessons learned from rabbits relevant to human disease52
Oxysterols in the development of diabetes and cardiovascular diseases52
Mitochondrial redox state, bioenergetics, and calcium transport in caloric restriction: A metabolic nexus51
Exogenous DNA enhances DUOX2 expression and function in human pancreatic cancer cells by activating the cGAS-STING signaling pathway51
MOTS-c improves intrinsic muscle mitochondrial bioenergetic health and efficiency in a PGC-1α/AMPK-dependent manner51
Antidepressant effect of the peptide EIILEAGK from Apostichopus japonicus via inflammatory and mitochondrial regulations in a lipopolysaccharide mouse model51
Mitochondria-tau association promotes cognitive decline and hippocampal bioenergetic deficits during the aging51
Mitochondrial quality control in non-exudative age-related macular degeneration: From molecular mechanisms to structural and functional recovery50
Developing a physiologically relevant cell model of ferroptosis in cardiomyocytes50
Interferon-γ induces salivary gland epithelial cell ferroptosis in Sjogren's syndrome via JAK/STAT1-mediated inhibition of system Xc-50
Hernandonine-mediated autophagic cell death in hepatocellular carcinoma: Interplay of p53 and YAP signaling pathways49
Carnosine supplementation Restores Mitochondrial–Synaptic Network Integrity in the Cerebellum of an ALS Model49
Phytocannabinoids modulate NO levels, NOX activation and HO-1 expression in M1 polarized macrophages49
N6-methyladenosine regulated FZD7 inhibits ferroptosis in endometriosis via β-catenin/SLC7A11 pathway48
Acetylation of mtHSP70 at Lys595/653 affecting its interaction between GrpEL1 regulates glioblastoma progression via UPRmt47
PET117 assembly factor stabilizes translation activator TACO1 thereby upregulates mitochondria-encoded cytochrome C oxidase 1 synthesis47
Assembly of mitochondrial succinate dehydrogenase in human health and disease47
Exosomes from tumor-associated neutrophils suppress ferroptosis and confer chemoresistance in gastric cancer via miR-9-3p/ACSL4 axis47
Redox regulation of cell migration via Nischarin S-glutathionylation47
Targeting ER stress/ROS-driven VEGF signaling axis: AdipoRon as a multifunctional therapeutic agent for alkali burn-induced corneal neovascularization47
Coenzyme Q10 and nicotinamide nucleotide transhydrogenase: Sentinels for mitochondrial hydrogen peroxide signaling46
β-Sitosterol targets ASS1 for Nrf2 ubiquitin-dependent degradation, inducing ROS-mediated apoptosis via the PTEN/PI3K/AKT signaling pathway in ovarian cancer46
Mitochondrial NOX4 drives atrial fibrillation via redox-dependent structural remodeling and fibrosis46
cGAS-STING signaling pathway promotes hypoxia-induced renal fibrosis by regulating PFKFB3-mediated glycolysis46
Epigenetic and “redoxogenetic” adaptation to physical exercise45
SYNJ2BP ameliorates intervertebral disc degeneration by facilitating mitochondria-associated endoplasmic reticulum membrane formation and mitochondrial Zn2+ homeostasis45
Cyanidin and delphinidin restore colon physiology in high fat diet-fed mice: Involvement of TLR-4 and redox-regulated signaling45
Peroxidasin is associated with a mesenchymal-like transcriptional phenotype and promotes invasion in metastatic melanoma45
CIRBP regulates mitochondrial respiratory function and modulates neuronal developmental abnormalities induced by perinatal hypoxia45
Carboxylesterase 2A gene knockout or enzyme inhibition alleviates steatohepatitis in rats by regulating PPARγ and endoplasmic reticulum stress44
Mechanistic insights into iron oxide nanoparticles-induced iron deregulation and mitochondrial dysfunction in yellow catfish Pelteobagrus fulvidraco: Comparison with ferrous sulphate44
Extracellular vesicle-mediated transcellular mitophagy as a modulatory target for moderate hyperoxia-induced alveolar developmental arrest in bronchopulmonary dysplasia44
Physiological roles of reactive oxygen species in sleep homeostasis44
Age-dependent reprogramming of vascular metabolism compromises endothelial resilience to inflammation-induced endothelial dysfunction44
Enduring metabolic modulation in the cardiac tissue of elderly CD-1 mice two months post mitoxantrone treatment44
Epigenetically activated MIR100HG regulates UPF1-mediated oxidative stress to promote pulmonary vascular immune microenvironment remodeling44
GSK-3β-dependent Nrf2 antioxidant response modulates ferroptosis of lens epithelial cells in age-related cataract43
In vivo chemogenetic generation of intraneuronal H2O243
Copper exerts cytotoxicity through inhibition of iron-sulfur cluster biogenesis on ISCA1/ISCA2/ISCU assembly proteins43
Brain lipidomics identifies mitochondrial redox dysfunction and metabolic trade-offs associated with Parkinson's disease-like pathology induced by Nanoplastics exposure43
Allogeneic platelet-rich plasma inhibits ferroptosis in promoting wound repair of type 2 diabetic ulcers43
Oxysterols in the defense against viral infections in humans42
Erianin inhibits the growth and metastasis through autophagy-dependent ferroptosis in KRASG13D colorectal cancer42
Redox control of antioxidants, metabolism, immunity, and development at the core of stress adaptation of the oyster Crassostrea gigas to the dynamic intertidal environment42
The effect of riboflavin supplementation on the systemic redox status in healthy volunteers: A post-hoc analysis of the RIBOGUT trial42
Superoxide, nitric oxide and peroxynitrite production by macrophages under different physiological oxygen tensions42
SGLT1 inhibition alleviates radiation-induced intestinal damage through promoting mitochondrial homeostasis42
Cigarette tar mediates macrophage ferroptosis in atherosclerosis through the hepcidin/FPN/SLC7A11 signaling pathway42
NLRP3 inflammasome-mitochondrion loop in autism spectrum disorder42
Pharmacological targeting of endothelial nitric oxide synthase dysfunction and nitric oxide replacement therapy42
Lysosomal lipid peroxidation triggers ferroptosis induction41
Regulation of DJ-1 by CoAlation in Parkinson’s Disease41
The exposome concept41
Effects of vitamin C supplementation on individualized oxidative stress and inflammation responses: A set of n-of-1 trials41
Age-dependent roles of Toll-like receptor 4 in islet inflammation and endocrine function41
Lysosomal membrane-targeting unlocks exceptional ferroptosis suppression41
Anti-inflammatory and anti-glycative properties of zinc-enriched spirulina in diet-induced obese/diabetic mice40
Membranes and thiols – will they ever become friends again in the presence of oxygen?40
Inflammasome involvement in skin response to pollution exposure40
Cerebral damage by noise and/or PM (UFP) in preclinical models – implications for Alzheimer’s disease40
NADPH Oxidase 4-mediated Fibrosis Contributes to Heart Failure with Preserved Ejection Fraction40
Telomeric noncoding RNA TERRA and its regulatory network in murine heart failure40
Dietary Supplementation with 23-Hydroxy Ursolic Acid Reduces the Severity and Incidence of Acute Experimental Autoimmune Encephalomyelitis (EAE) in a Murine Model of Multiple Sclerosis39
ERO1 alpha deficiency impairs angiogenesis by increasing N-glycosylation of a proangiogenic VEGFA38
N-Terminal proteomic profiling reveals distinct fragmentation patterns of proteins in different types of human atherosclerotic plaques38
Potent antioxidant and mitochondrial-protective effects of ATH434, a novel therapeutic with moderate iron-binding affinity, in HT22 and iPSC-derived cellular models of oxidative stress38
Role of the NADPH oxidase NOX4 in the liver tumour microenvironment38
Succinate in the Regulation of Ischemia and Reperfusion Injury38
Cell-free circulating mitochondrial DNA: An emerging biomarker for airborne particulate matter associated with cardiovascular diseases37
NRF2 Dysregulation in Impairs Beta-Cell Mass Expansion during Pregnancy Leading to Gestational Diabetes37
Dehydroascorbic acid impairs neurite growth through RIPK1-associated caspase activation37
Redox-Dependent Regulation of DUOX1 NADPH Oxidase Activity37
Influence of plasma halide, pseudohalide and nitrite ions on myeloperoxidase-mediated protein and extracellular matrix damage36
Editorial Board36
Impact of exercise-induced redox signalling on extracellular vesicles dynamics in muscle cells36
Hyperactivation of the m6A demethylase FTO to down-regulate SLC7A11/xCT-mediated redox homeostasis and epigenetic remodeling in facial infiltrating lipomatosis36
Photosensitized isomerization of resveratrol: Evaluation of energy and electron transfer pathways36
Nano and microplastics (NMPS) impair meiosis and alter the redox state of the mouse female germ cell36
Hyperoxic recovery interferes with the metabolic imprint of hypoxic exercise36
Sulfide quinone oxidoreductase (SQR)-mediated cross-species mitochondrial sulfur respiration by supersulfides36
Age and sex-related differences in stress response due to disuse atrophy in skeletal muscle36
Redisulphid: A structural bioinformatic screen for identifying drug-targetable redox-regulated disulphides35
Cyclo-octa-sulfur contributes to energy metabolism in mitochondria35
USP15 stabilizes RSK1 and promotes temozolomide resistance in glioblastoma35
Reactive nitrogen species as therapeutic targets for autophagy/mitophagy modulation to relieve neurodegeneration in multiple sclerosis: Potential application for drug discovery35
Sexual dimorphism in redox homeostasis of visceral adipose tissue in aged mices35
Editorial Board35
When nitrosative stress hits the endoplasmic reticulum: Possible implications in oxLDL/oxysterols-induced endothelial dysfunction34
The glutathione system maintains the thiol redox balance in the mitochondria of fission yeast34
Mapping of oxidative modifications on the alpha-keto glutarate dehydrogenase complex induced by singlet oxygen: Effects on structure and activity34
METTL3 deficiency leads to ovarian insufficiency due to IL-1β overexpression in theca cells34
Macrophage CAPN4 regulates CVB3-induced cardiac inflammation and injury by promoting NLRP3 inflammasome activation and phenotypic transformation to the inflammatory subtype34
Acrolein produced by glioma cells under hypoxia inhibits neutrophil AKT activity and suppresses anti-tumoral activities34
Assessment of p-phenylenediamine toxicity in subcellular compartments of hepatic and ocular tissues in Oreochromis mossambicus (Peters, 1852)34
Effects of dietary inorganic nitrate on blood pressure during and post-exercise recovery: A systematic review and meta-analysis of randomized placebo-controlled trials34
MitoSOX Green for Visualizing Superoxide in Mitochondria34
Identifying genetic overlaps in obesity and metabolic disorders unlocking unique and shared mechanistic insights34
Nonthermal plasma boosted dichloroacetate induces metabolic shifts to combat glioblastoma CSCs via oxidative stress33
Mitochondrial ACSS1-K635 acetylation knock-in mice exhibit altered liver lipid metabolism on a ketogenic diet33
Responses of individual and combined polystyrene and polymethyl methacrylate nanoplastics on hormonal content, fluorescence/photochemistry of chlorophylls and ROS scavenging capacity in Lemna minor un33
Corrigendum to “Oxidative stress-mediated DNA damage promotes selective degradation of nuclear components via noncanonical autophagy in triple-negative breast cancer cells” [Free Radic. Biol. Med. 24233
Flavan-3-ol-methylxanthine interactions: Modulation of flavan-3-ol bioavailability in volunteers with a functional colon and an ileostomy33
Knockdown of SIRT3 perturbs protective effects of irisin against bone loss in diabetes and periodontitis33
Newly synthetized HV-12 prevents aggregation of the platelets via P2Y1232
Rewired Sulfur Amino Acid Metabolism Provides Thiols Supporting Cell Survival in the Absence of Disulfide Reducing Power32
Corrigendum to “TG2 (transglutaminase 2) promotes PINK1/Parkin-dependent mitophagy in pulmonary hypertension by regulating the TRPC6” [Free Radic. Biol. Med. 249 (2026) 336–355]32
Prelims32
In vitro and in cellula tyrosine nitration by 5-methyl-1,4-dinitro-1H-imidazole (DNI), a photochemical nitrating agent: synthesis and biochemical characterization32
Annotation, Diversity and Evolution of Selenocysteine-containing Oxidoreductases in Eukaryotes32
P4HB UFMylation regulates mitochondrial function and oxidative stress32
Identification of the N-terminally truncated Nrf2 isoform with different regulation and indications of novel functions of Nrf232
Transcription factor NRF2 regulates the permeability of the blood brain barrier at the level of ANGPT1/2-TIE2 signaling32
Mitochondrial Metabolic Heterogeneity in Senescent Cells Induced by Different Stimuli is Associated with the Acquisition of a Persistent DNA Damage Response and Secretory Phenotype31
[YIA] S-nitrosation governs the appearance and disposal of cytoplasmic DNA in endothelial cells31
Polyamines-a novel molecular coordinator of nitro oxidative signaling in barley senescing leaf31
Time-dependent association between an RNA oxidation biomarker (8-oxoGuo) and colorectal cancer risk31
[YIA] Changes in NADPH oxidase activity in E-cigarette vapor condensate exposed cultured cells and the role of acrolein31
Free radicals mediated protein oxidation: Detection and functional relevance in macrophage polarization31
[YIA] Identification of intramembrane proteases that activate membrane-bound transcription factors during mitochondrial retrograde regulation31
The Effects of Esculin Treatment on Mitochondrial Dynamics and Epigenetics in the Early Stage of Experimental Diabetic Nephropathy31
Diamond magnetometry to understand male reproductive decay during aging31
Methodological, statistical and interpretive considerations in personalised redox biology31
BMX-001 can reverse radiation-induced fibroblast activation and senescence31
Co-exposure to urban particulate matter and aircraft noise adversely impacts the cerebro-pulmonary-cardiovascular axis in mice30
Glutathione S-transferase P nuclear distribution and Nrf2/Keap1 interacting properties mark the GSH-dependent drug resistance phenotype of hepatocellular carcinoma30
Dietary nitrate improves nitric oxide-mediated neurovascular coupling and spatial memory in a rodent model of type 2 diabetes30
Redox regulation of tumor progression and metastasis: lessons from mouse models to clinical strategies30
Urban air inhalation exacerbates the oxinflammatory response after an acute lung injury, hindering alveolar epithelium repair30
Role of the Sympathetic Nervous System in Amyotrophic Lateral Sclerosis (ALS)30
Quantifying redox transcription factor dynamics as a tool to investigate redox signalling30
Skin redoxome and the photochemical membrane leakage30
In vitro antiplatelet activity and characterization of Hallado Aleman bean30
Celastrol confers ferroptosis resistance via AKT/GSK3β signaling in high-fat diet-induced cardiac injury30
Molecular aspects of the exercise response and training adaptation in skeletal muscle30
Evidence of impaired mitochondrial cellular bioenergetics in ocular fibroblasts derived from glaucoma patients29
MTP18 inhibition triggers mitochondrial hyperfusion to induce apoptosis through ROS-mediated lysosomal membrane permeabilization-dependent pathway in oral cancer29
ASCL1-mediated ferroptosis resistance enhances the progress of castration-resistant prostate cancer to neurosecretory prostate cancer29
Mercuric chloride induces sequential activation of ferroptosis and necroptosis in chicken embryo kidney cells by triggering ferritinophagy29
ROS and redox regulation of cell-to-cell and systemic signaling in plants during stress29
Longitudinal metabolomics integrated with machine learning identifies novel biomarkers of gestational diabetes mellitus29
Baicalein limits osteoarthritis development by inhibiting chondrocyte ferroptosis29
Cytochrome b5 reductase 4 efficiently reduces neuroglobin and cytoglobin28
YTHDF2–m6A regulation of DHRS3 at LRAT-organized organelle contacts orchestrates redox to drive radioresistance in esophageal squamous cell carcinoma28
MT2A buffering exhaustion marks cuproptosis in severe COVID-19: Multi-omics integration, computational modeling, and experimental validation28
Anesthetic propofol inhibits ferroptosis and aggravates distant cancer metastasis via Nrf2 upregulation28
Oxidative stress-induced proinflammatory secretion from retinal pigment epithelium disrupts NAD+ metabolism via CD38 on macrophages leading to immune microenvironment dysregulation28
Selenium deficiency causes hypertension by increasing renal AT1 receptor expression via GPx1/H2O2/NF-κB pathway27
IL-17A is a key regulator of neuroinflammation and neurodevelopment in cognitive impairment induced by sevoflurane27
Nanoplastic PS and cadmium co-exposure accelerates ferroptosis mediated by HIF-1α-related signaling in spermatogonium27
Low-dose valproic acid ameliorates osteoporosis by restoring redox homeostasis and suppressing ferritinophagy-dependent ferroptosis via EZH2/H3K27me3 signaling27
cGAS-STING signaling pathway promotes ischemic kidney injury by regulating HK3-mediated lipid accumulation27
Mitochondrial Redox Signaling and Organelle-Targeted Strategies: Balancing Pro-Thrombotic Environmental Risks with Natural and Synthetic Antiplatelet Therapies27
Menaquinone-4 prevents medication-related osteonecrosis of the jaw through the SIRT1 signaling-mediated inhibition of cellular metabolic stresses-induced osteoblast apoptosis27
Targeted nuclear degranulation of neutrophils in the shock stage of severe burns drives rapid neutrophil extracellular trap release during infection to mediate acute lung injury27
Ginkgolic acid ameliorates pressure overload-induced cardiac remodeling by inhibiting SAE1 and activating the NRF2/HMOX1 pathway27
Piezoeletric cold atmospheric plasma induces apoptosis and autophagy in human hepatocellular carcinoma cells through blocking glycolysis and AKT/mTOR/HIF-1α pathway27
Macrophages hijack carbapenem-resistance hypervirulent Klebsiella pneumoniae by blocking SLC7A11/GSH-manipulated iron oxidative stress27
Discovery of a novel beta adrenergic-mitochondrial signaling pathway in Th17 lymphocyte polarization26
Composition, bioavailability and bioactivity of galloylated flavan-3-ols from Vitis vinífera L.cv. Tannat pomace26
Exploiting Mitochondrial Redox Vulnerabilities in Gastric Cancer26
The Role of Lysosomal Two-Pore Channels in Ischemia Induced Cell Death26
Anthocyanins-Related Antioxidant Capacity as a ‘Reporter’ Trait For Sweet Potato Breeding26
Discovery of Gallic Acid-Based Mitochondriotropic Antioxidant Attenuates LPS-Induced Neuroinflammation26
KEAP1 Dimer-Driven Contributions to the Architecture of the C151 Catalytic Pocket26
Dimethyl labeling of N-terminal amines allows unambiguous identification of protein crosslinks26
Finding vitamin Ex26
Targeting arachidonic acid lipoxygenase-12 (ALOX12) in the pancreatic ductal adenocarcinoma tumor microenvironment to enhance therapy outcomes26
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