Free Radical Biology and Medicine

Papers
(The TQCC of Free Radical Biology and Medicine is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)
ArticleCitations
Lipid peroxidation and ferroptosis: The role of GSH and GPx4773
Role of oxidative stress in the pathogenesis of nonalcoholic fatty liver disease595
Air pollution and its effects on the immune system337
Ferritinophagy-mediated ferroptosis is involved in sepsis-induced cardiac injury315
Inhibition of ferroptosis alleviates atherosclerosis through attenuating lipid peroxidation and endothelial dysfunction in mouse aortic endothelial cell239
Ascorbic acid: The chemistry underlying its antioxidant properties230
Inhibition of ferroptosis by up-regulating Nrf2 delayed the progression of diabetic nephropathy202
Oxidative stress in the pathophysiology of type 2 diabetes and related complications: Current therapeutics strategies and future perspectives172
Ubiquitin-specific protease 7 promotes ferroptosis via activation of the p53/TfR1 pathway in the rat hearts after ischemia/reperfusion153
Beyond repression of Nrf2: An update on Keap1148
Resveratrol reduces obesity in high-fat diet-fed mice via modulating the composition and metabolic function of the gut microbiota136
Potential therapeutic use of ebselen for COVID-19 and other respiratory viral infections130
Oxidative stress and the cardiovascular effects of air pollution127
Verification of ferroptosis and pyroptosis and identification of PTGS2 as the hub gene in human coronary artery atherosclerosis117
Ferroptosis was more initial in cell death caused by iron overload and its underlying mechanism in Parkinson's disease115
Potential benefits and risks of omega-3 fatty acids supplementation to patients with COVID-19114
Senolytics and senomorphics: Natural and synthetic therapeutics in the treatment of aging and chronic diseases109
Mitochondrial oxidative stress mediated Fe-induced ferroptosis via the NRF2-ARE pathway106
Endoplasmic reticulum stress-mediated autophagy activation is involved in cadmium-induced ferroptosis of renal tubular epithelial cells103
Elabela alleviates ferroptosis, myocardial remodeling, fibrosis and heart dysfunction in hypertensive mice by modulating the IL-6/STAT3/GPX4 signaling102
The emerging potential of cold atmospheric plasma in skin biology102
Pretreatment with kaempferol attenuates microglia-mediate neuroinflammation by inhibiting MAPKs–NF–κB signaling pathway and pyroptosis after secondary spinal cord injury102
Homocysteine induces oxidative stress and ferroptosis of nucleus pulposus via enhancing methylation of GPX4101
Revisiting pharmacology of oxidative stress and endothelial dysfunction in cardiovascular disease: Evidence for redox-based therapies97
Exosomes from adipose-derived stem cells alleviate the inflammation and oxidative stress via regulating Nrf2/HO-1 axis in macrophages96
Ambient particulate matter oxidative potential: Chemical determinants, associated health effects, and strategies for risk management95
Green tea derivative (−)-epigallocatechin-3-gallate (EGCG) confers protection against ionizing radiation-induced intestinal epithelial cell death both in vitro and in vivo93
AGE/RAGE in diabetic kidney disease and ageing kidney93
Targeting SLC3A2 subunit of system XC− is essential for m6A reader YTHDC2 to be an endogenous ferroptosis inducer in lung adenocarcinoma91
Hypoxia inhibits RANKL-induced ferritinophagy and protects osteoclasts from ferroptosis90
The role of glutathione redox imbalance in autism spectrum disorder: A review87
Defective mitophagy and synaptic degeneration in Alzheimer's disease: Focus on aging, mitochondria and synapse85
Antioxidant properties of anthocyanins and their mechanism of action in atherosclerosis83
The role of NO in COVID-19 and potential therapeutic strategies81
Role of myeloperoxidase and oxidant formation in the extracellular environment in inflammation-induced tissue damage81
Reactivity and degradation products of tryptophan in solution and proteins80
Energy substrate metabolism and mitochondrial oxidative stress in cardiac ischemia/reperfusion injury80
Regulation of Nrf2 by phosphorylation: Consequences for biological function and therapeutic implications77
Metformin attenuates hyperlipidaemia-associated vascular calcification through anti-ferroptotic effects77
Therapeutic potential of targeting oxidative stress in diabetic cardiomyopathy76
Nrf2 for protection against oxidant generation and mitochondrial damage in cardiac injury75
Browsing the oldest antioxidant enzyme: catalase and its multiple regulation in cancer74
Cold plasma seed priming modulates growth, redox homeostasis and stress response by inducing reactive species in tomato (Solanum lycopersicum)73
Transcription factor NRF2 as a promising therapeutic target for Alzheimer’s disease71
Nitrate ameliorates dextran sodium sulfate-induced colitis by regulating the homeostasis of the intestinal microbiota71
Butyrate alleviates oxidative stress by regulating NRF2 nuclear accumulation and H3K9/14 acetylation via GPR109A in bovine mammary epithelial cells and mammary glands70
The glutathione peroxidase family: Discoveries and mechanism69
Mitochondrial dysfunction promotes aquaporin expression that controls hydrogen peroxide permeability and ferroptosis69
The relevance of pathophysiological alterations in redox signaling of 4-hydroxynonenal for pharmacological therapies of major stress-associated diseases68
Role of necroptosis in chronic hepatic inflammation and fibrosis in a mouse model of increased oxidative stress67
Drp1-regulated PARK2-dependent mitophagy protects against renal fibrosis in unilateral ureteral obstruction67
Molecular mechanisms underlying health benefits of tea compounds67
The role of glutathione peroxidase-1 in health and disease67
PINK1-mediated mitophagy protects against hepatic ischemia/reperfusion injury by restraining NLRP3 inflammasome activation66
Spermidine endows macrophages anti-inflammatory properties by inducing mitochondrial superoxide-dependent AMPK activation, Hif-1α upregulation and autophagy64
Oxidative stress in cardiac hypertrophy: From molecular mechanisms to novel therapeutic targets64
Glycyrrhetinic acid induces oxidative/nitrative stress and drives ferroptosis through activating NADPH oxidases and iNOS, and depriving glutathione in triple-negative breast cancer cells64
Mitochondrial unfolded protein response: An emerging pathway in human diseases64
Impact of air pollution on intestinal redox lipidome and microbiome64
Beneficial effects of dietary supplementation with olive oil, oleic acid, or hydroxytyrosol in metabolic syndrome: Systematic review and meta-analysis62
Vitamin E alpha- and gamma-tocopherol mitigate colitis, protect intestinal barrier function and modulate the gut microbiota in mice61
The interplay among oxidative stress, brain insulin resistance and AMPK dysfunction contribute to neurodegeneration in type 2 diabetes and Alzheimer disease61
The dark side of gamma-glutamyltransferase (GGT): Pathogenic effects of an ‘antioxidant’ enzyme60
Hypoxic preconditioning combined with curcumin promotes cell survival and mitochondrial quality of bone marrow mesenchymal stem cells, and accelerates cutaneous wound healing via PGC-1α/SIRT3/HIF-1α s59
Hydrogen sulfide alleviates particulate matter-induced emphysema and airway inflammation by suppressing ferroptosis59
Disulfiram suppresses NLRP3 inflammasome activation to treat peritoneal and gouty inflammation59
DNA damage and oxidant stress activate p53 through differential upstream signaling pathways59
Cigarette smoke-inactivated SIRT1 promotes autophagy-dependent senescence of alveolar epithelial type 2 cells to induce pulmonary fibrosis58
mTOR in Alzheimer disease and its earlier stages: Links to oxidative damage in the progression of this dementing disorder58
Relevance of Nrf2 and heme oxygenase-1 in articular diseases58
The homeostatic role of hydrogen peroxide, superoxide anion and nitric oxide in the vasculature57
NAC alleviative ferroptosis in diabetic nephropathy via maintaining mitochondrial redox homeostasis through activating SIRT3-SOD2/Gpx4 pathway57
Mitochondrial ROS and mitochondria-targeted antioxidants in the aged heart57
Wedelolactone alleviates acute pancreatitis and associated lung injury via GPX4 mediated suppression of pyroptosis and ferroptosis56
Oroxylin a promotes PGC-1α/Mfn2 signaling to attenuate hepatocyte pyroptosis via blocking mitochondrial ROS in alcoholic liver disease55
AMP-activated protein kinase: A remarkable contributor to preserve a healthy heart against ROS injury55
Oxidative stress in air pollution research55
Increasing ovarian NAD+ levels improve mitochondrial functions and reverse ovarian aging55
Upregulation of oxidative stress gene markers during SARS-COV-2 viral infection54
Altered glucose metabolism in Alzheimer's disease: Role of mitochondrial dysfunction and oxidative stress53
The potential link between inherited G6PD deficiency, oxidative stress, and vitamin D deficiency and the racial inequities in mortality associated with COVID-1953
Redox signaling pathways in unilateral ureteral obstruction (UUO)-induced renal fibrosis52
Iron regulatory protein 2 is required for artemether -mediated anti-hepatic fibrosis through ferroptosis pathway52
Camellia oil alleviates the progression of Alzheimer's disease in aluminum chloride-treated rats51
A novel mechanism linking ferroptosis and endoplasmic reticulum stress via the circPtpn14/miR-351-5p/5-LOX signaling in melatonin-mediated treatment of traumatic brain injury51
Irisin protects against sepsis-associated encephalopathy by suppressing ferroptosis via activation of the Nrf2/GPX4 signal axis50
Discovery of new therapeutic redox targets for cardioprotection against ischemia/reperfusion injury and heart failure50
Mitoquinone attenuates vascular calcification by suppressing oxidative stress and reducing apoptosis of vascular smooth muscle cells via the Keap1/Nrf2 pathway50
Oxidative stress and regeneration49
Natural and synthetic antioxidants targeting cardiac oxidative stress and redox signaling in cardiometabolic diseases49
MitoQ alleviates LPS-mediated acute lung injury through regulating Nrf2/Drp1 pathway49
Tannic acid, a promising anti-photoaging agent: Evidences of its antioxidant and anti-wrinkle potentials, and its ability to prevent photodamage and MMP-1 expression in L929 fibroblasts exposed to UVB49
Bufotalin induces ferroptosis in non-small cell lung cancer cells by facilitating the ubiquitination and degradation of GPX448
microRNA-181 serves as a dual-role regulator in the development of human cancers48
Angelica dahurica promoted angiogenesis and accelerated wound healing in db/db mice via the HIF-1α/PDGF-β signaling pathway48
Geniposide protects against sepsis-induced myocardial dysfunction through AMPKα-dependent pathway47
The circular RNA TLK1 exacerbates myocardial ischemia/reperfusion injury via targeting miR-214/RIPK1 through TNF signaling pathway47
Roflumilast prevents ischemic stroke-induced neuronal damage by restricting GSK3β-mediated oxidative stress and IRE1α/TRAF2/JNK pathway47
Vitexin alleviates high-fat diet induced brain oxidative stress and inflammation via anti-oxidant, anti-inflammatory and gut microbiota modulating properties47
Nrf2 knockout altered brain iron deposition and mitigated age-related motor dysfunction in aging mice47
The role of Nrf2 in acute kidney injury: Novel molecular mechanisms and therapeutic approaches47
Cadmium attenuates testosterone synthesis by promoting ferroptosis and blocking autophagosome-lysosome fusion46
Iron overload promotes intervertebral disc degeneration via inducing oxidative stress and ferroptosis in endplate chondrocytes46
Gamma-tocopherol, a major form of vitamin E in diets: Insights into antioxidant and anti-inflammatory effects, mechanisms, and roles in disease management46
Aerobic exercise alleviates oxidative stress-induced apoptosis in kidneys of myocardial infarction mice by inhibiting ALCAT1 and activating FNDC5/Irisin signaling pathway46
m6A methylation is required for dihydroartemisinin to alleviate liver fibrosis by inducing ferroptosis in hepatic stellate cells46
Atorvastatin alleviates microglia-mediated neuroinflammation via modulating the microbial composition and the intestinal barrier function in ischemic stroke mice46
Vitamin E as an essential micronutrient for human health: Common, novel, and unexplored dietary sources45
Lycopene prevents the progression of lipotoxicity-induced nonalcoholic steatohepatitis by decreasing oxidative stress in mice45
Pharmacological targeting and the diverse functions of the metastasis suppressor, NDRG1, in cancer45
Iron homeostasis and disorders revisited in the sepsis44
TIGAR drives colorectal cancer ferroptosis resistance through ROS/AMPK/SCD1 pathway44
Quercetin alleviates kainic acid-induced seizure by inhibiting the Nrf2-mediated ferroptosis pathway44
Protein S-nitrosylation and oxidation contribute to protein misfolding in neurodegeneration44
Pharmacological inhibition of MELK restricts ferroptosis and the inflammatory response in colitis and colitis-propelled carcinogenesis44
Reflections of an aging free radical44
Lipid oxidation that is, and is not, inhibited by vitamin E: Consideration about physiological functions of vitamin E44
How the redox state regulates immunity43
Melatonin alleviates heat stress-induced oxidative stress and apoptosis in human spermatozoa43
Baicalin promotes liver regeneration after acetaminophen-induced liver injury by inducing NLRP3 inflammasome activation43
Heme oxygenase-1 modulation: A potential therapeutic target for COVID-19 and associated complications42
Mitochondrial SIRT3 confers neuroprotection in Huntington's disease by regulation of oxidative challenges and mitochondrial dynamics41
The role of ceramide accumulation in human induced pluripotent stem cell-derived cardiomyocytes on mitochondrial oxidative stress and mitophagy41
Chronic impairment of mitochondrial bioenergetics and β-oxidation promotes experimental AKI-to-CKD transition induced by folic acid40
Heme Oxygenase-1 in liver transplant ischemia-reperfusion injury: From bench-to-bedside40
Natural ingredients-derived antioxidants attenuate H2O2-induced oxidative stress and have chondroprotective effects on human osteoarthritic chondrocytes via Keap1/Nrf2 pathway40
Silica nanoparticles induce pyroptosis and cardiac hypertrophy via ROS/NLRP3/Caspase-1 pathway40
Role of Nrf2 in MALAT1/ HIF-1α loop on the regulation of angiogenesis in diabetic foot ulcer40
The antioxidant activity and neuroprotective mechanism of isoliquiritigenin40
The role of NADPH oxidases in neuronal development39
Cyanidin-3-O-β-glucoside inactivates NLRP3 inflammasome and alleviates alcoholic steatohepatitis via SirT1/NF-κB signaling pathway39
Nrf2 as a regulator of mitochondrial function: Energy metabolism and beyond39
Indoleamine 2, 3-dioxygenase 1enhanceshepatocytes ferroptosis in acute immune hepatitis associated with excess nitrative stress39
Spermidine rescues the deregulated autophagic response to oxidative stress of osteoarthritic chondrocytes39
Heme oxygenase-1(HO-1) regulates Golgi stress and attenuates endotoxin-induced acute lung injury through hypoxia inducible factor-1α (HIF-1α)/HO-1 signaling pathway38
Primary Coenzyme Q deficiencies: A literature review and online platform of clinical features to uncover genotype-phenotype correlations38
Oxidative contribution of air pollution to extrinsic skin ageing38
Downregulation of dihydrolipoyl dehydrogenase by UVA suppresses melanoma progression via triggering oxidative stress and altering energy metabolism38
The calcium–iron connection in ferroptosis-mediated neuronal death38
Adipose tissue macrophage-derived exosomes induce ferroptosis via glutathione synthesis inhibition by targeting SLC7A11 in obesity-induced cardiac injury38
Astrocyte hepcidin ameliorates neuronal loss through attenuating brain iron deposition and oxidative stress in APP/PS1 mice37
Mediterranean diet and cognitive function: From methodology to mechanisms of action37
NFκB promotes oxidative stress-induced necrosis and ischemia/reperfusion injury by inhibiting Nrf2-ARE pathway37
Multiple functions of 2-Cys peroxiredoxins, I and II, and their regulations via post-translational modifications37
Susceptibility of the patients infected with Sars-Cov2 to oxidative stress and possible interplay with severity of the disease37
Age-dependent accumulation of dicarbonyls and advanced glycation endproducts (AGEs) associates with mitochondrial stress36
The effect of oxidative and reductive stress on semen parameters and functions of physiologically normal human spermatozoa36
Aging lens epithelium is susceptible to ferroptosis36
Mitochondrial superoxide/hydrogen peroxide: An emerging therapeutic target for metabolic diseases36
Vitamin E research: Past, now and future35
Vitamin E: How much is enough, too much and why!35
Neuroinflammation-mediated mitochondrial dysregulation involved in postoperative cognitive dysfunction35
Novel perspectives on redox signaling in red blood cells and platelets in cardiovascular disease35
Rehmapicroside ameliorates cerebral ischemia-reperfusion injury via attenuating peroxynitrite-mediated mitophagy activation35
Arsenic, cadmium, and selenium exposures and bone mineral density-related endpoints: The HORTEGA study35
Conductivity augments ROS and RNS delivery and tumor toxicity of an argon plasma jet35
Azocompounds as generators of defined radical species: Contributions and challenges for free radical research35
Oxidative stress-mediated alterations in histone post-translational modifications35
Curcumin–cyclodextrin/cellulose nanocrystals improve the phenotype of Charcot-Marie-Tooth-1A transgenic rats through the reduction of oxidative stress35
A white paper on Phospholipid Hydroperoxide Glutathione Peroxidase (GPx4) forty years later34
NRF2 activation by reversible KEAP1 binding induces the antioxidant response in primary neurons and astrocytes of a Huntington's disease mouse model34
Role of Nrf2 dysfunction in the pathogenesis of diabetic nephropathy: Therapeutic prospect of epigallocatechin-3-gallate34
Tumor cell metabolism correlates with resistance to gas plasma treatment: The evaluation of three dogmas34
The decrease of selenoprotein K induced by selenium deficiency in diet improves apoptosis and cell progression block in chicken liver via the PTEN/PI3K/AKT pathway34
Dioscin ameliorates methotrexate-induced liver and kidney damages via adjusting miRNA-145-5p-mediated oxidative stress34
Mitochondrial and glucose metabolic dysfunctions in granulosa cells induce impaired oocytes of polycystic ovary syndrome through Sirtuin 334
H-ferritin suppression and pronounced mitochondrial respiration make Hepatocellular Carcinoma cells sensitive to RSL3-induced ferroptosis34
Apelin-13 induces mitophagy in bone marrow mesenchymal stem cells to suppress intracellular oxidative stress and ameliorate osteoporosis by activation of AMPK signaling pathway34
A novel function of ATF3 in suppression of ferroptosis in mouse heart suffered ischemia/reperfusion33
Redox regulation of cutaneous inflammasome by ozone exposure33
Resveratrol and its derivative pterostilbene attenuate oxidative stress-induced intestinal injury by improving mitochondrial redox homeostasis and function via SIRT1 signaling33
Interventional study with vitamin E in cardiovascular disease and meta-analysis33
Low plasma ergothioneine levels are associated with neurodegeneration and cerebrovascular disease in dementia33
Oxygen sensing, mitochondrial biology and experimental therapeutics for pulmonary hypertension and cancer33
Crosstalk between oxidative stress-induced apoptotic and autophagic signaling pathways in Zn(II) phthalocyanine photodynamic therapy of melanoma33
Ginsenoside Rg1 prevents bone marrow mesenchymal stem cell senescence via NRF2 and PI3K/Akt signaling33
Mitochondria signaling to the epigenome: A novel role for an old organelle33
Mitochondrial DNA, oxidants, and innate immunity33
Vitamin D deficiency exacerbates Alzheimer-like pathologies by reducing antioxidant capacity33
MicroRNA-based regulatory mechanisms underlying the synergistic antioxidant action of quercetin and catechin in H2O2-stimulated HepG2 cells: Roles of BACH1 in Nrf2-dependent pathways32
Chronic intermittent hypoxia-induced mitochondrial dysfunction mediates endothelial injury via the TXNIP/NLRP3/IL-1β signaling pathway32
Nrf2 inhibition sensitizes breast cancer stem cells to ionizing radiation via suppressing DNA repair32
Characterization of disulfide (cystine) oxidation by HOCl in a model peptide: Evidence for oxygen addition, disulfide bond cleavage and adduct formation with thiols32
CYP11A1-derived vitamin D3 products protect against UVB-induced inflammation and promote keratinocytes differentiation32
AMPK and NRF2: Interactive players in the same team for cellular homeostasis?32
Low shear stress induced vascular endothelial cell pyroptosis by TET2/SDHB/ROS pathway32
Mitochondrial redox and TCA cycle metabolite signaling in the heart31
Ellagic acid protects Caco-2 cell monolayers against inflammation-induced permeabilization31
NQO1 mediates the anti-inflammatory effects of nootkatone in lipopolysaccharide-induced neuroinflammation by modulating the AMPK signaling pathway31
Adverse effect of superoxide-induced mitochondrial damage in granulosa cells on follicular development in mouse ovaries31
STING-dependent induction of lipid peroxidation mediates intestinal ischemia-reperfusion injury31
Manganese induces tumor cell ferroptosis through type-I IFN dependent inhibition of mitochondrial dihydroorotate dehydrogenase30
Altered redox regulation and S-glutathionylation of BiP contribute to bortezomib resistance in multiple myeloma30
Metabolism of natural forms of vitamin E and biological actions of vitamin E metabolites30
One-carbon epigenetics and redox biology of neurodegeneration30
Influence of cardiometabolic comorbidities on myocardial function, infarction, and cardioprotection: Role of cardiac redox signaling30
miR-15a-5p inhibits metastasis and lipid metabolism by suppressing histone acetylation in lung cancer30
Ursodeoxycholic acid protects against cisplatin-induced acute kidney injury and mitochondrial dysfunction through acting on ALDH1L230
Regulation of Nrf2 signaling pathway in heart failure: Role of extracellular vesicles and non-coding RNAs30
Plasma GSH levels and Alzheimer's disease. A prospective approach.: Results from the HELIAD study30
Antioxidant activity of highly hydroxylated fullerene C60 and its interactions with the analogue of α-tocopherol30
Therapeutic effects of non-saponin fraction with rich polysaccharide from Korean red ginseng on aging and Alzheimer's disease30
Increased mitochondrial content and function by resveratrol and select flavonoids protects against benzo[a]pyrene-induced bioenergetic dysfunction and ROS generation in a cell model of neoplastic tran30
ACSL4 and the lipoxygenases 15/15B are pivotal for ferroptosis induced by iron and PUFA dyshomeostasis in dopaminergic neurons29
Selenoprotein P – Selenium transport protein, enzyme and biomarker of selenium status29
Sirtuin 6 (SIRT6) regulates redox homeostasis and signaling events in human articular chondrocytes29
The molecular and physiological consequences of cold plasma treatment in murine skin and its barrier function29
STAT3-mediated ferroptosis is involved in ulcerative colitis29
Dihydrotanshinone I inhibits ovarian tumor growth by activating oxidative stress through Keap1-mediated Nrf2 ubiquitination degradation29
Flavonoid 4,4′-dimethoxychalcone induced ferroptosis in cancer cells by synergistically activating Keap1/Nrf2/HMOX1 pathway and inhibiting FECH29
The intestinal 3M (microbiota, metabolism, metabolome) zeitgeist – from fundamentals to future challenges29
Deiodinases control local cellular and systemic thyroid hormone availability29
Ferrostatin-1 obviates seizures and associated cognitive deficits in ferric chloride-induced posttraumatic epilepsy via suppressing ferroptosis29
Exosomes derived from human umbilical cord mesenchymal stem cells ameliorate experimental non-alcoholic steatohepatitis via Nrf2/NQO-1 pathway29
Canonical Wnt signaling works downstream of iron overload to prevent ferroptosis from damaging osteoblast differentiation29
Inflammation-dependent oxidative stress metabolites as a hallmark of amyotrophic lateral sclerosis29
Sanguinarine as a new chemical entity of thioredoxin reductase inhibitor to elicit oxidative stress and promote tumor cell apoptosis29
Compartmentally scavenging hepatic oxidants through AMPK/SIRT3-PGC1α axis improves mitochondrial biogenesis and glucose catabolism28
Empagliflozin attenuates the renal tubular ferroptosis in diabetic kidney disease through AMPK/NRF2 pathway28
Compromised immune/inflammatory responses in Rett syndrome28
Inhibition of Nrf2 degradation alleviates age-related osteoporosis induced by 1,25-Dihydroxyvitamin D deficiency28
Nrf2 contributes to the benefits of exercise interventions on age-related skeletal muscle disorder via regulating Drp1 stability and mitochondrial fission28
Protective role of hydrogen sulfide against diabetic cardiomyopathy via alleviating necroptosis28
Catalase: A critical node in the regulation of cell fate28
Activation of MAT2A-ACSL3 pathway protects cells from ferroptosis in gastric cancer28
Suppressing long noncoding RNA OGRU ameliorates diabetic retinopathy by inhibition of oxidative stress and inflammation via miR-320/USP14 axis28
Protective actions of nuclear factor erythroid 2-related factor 2 (NRF2) and downstream pathways against environmental stressors28
JNK-JUN-NCOA4 axis contributes to chondrocyte ferroptosis and aggravates osteoarthritis via ferritinophagy28
Functional segmentation of CoQ and cyt c pools by respiratory complex superassembly28
Mercuric chloride induces sequential activation of ferroptosis and necroptosis in chicken embryo kidney cells by triggering ferritinophagy28
PKCδ mediates mitochondrial ROS generation and oxidation of HSP60 to relieve RKIP inhibition on MAPK pathway for HCC progression28
Angiotensin II and leukocyte trafficking: New insights for an old vascular mediator. Role of redox-signaling pathways28
Insulin resistance, oxidative stress and mitochondrial defects in Ts65dn mice brain: A harmful synergistic path in down syndrome28
Coenzyme Q redox signalling and longevity27
Gamma irradiation promotes chemo-sensitization potential of gallic acid through attenuation of autophagic flux to trigger apoptosis in an NRF2 inactivation signalling pathway27
Sirtuin 3: Emerging therapeutic target for cardiovascular diseases27
Melatonin inhibits the apoptosis of rooster Leydig cells by suppressing oxidative stress via AKT-Nrf2 pathway activation27
Oxidative stress-induced aberrant lipid metabolism is an important causal factor for dysfunction of immunocytes from patients with systemic lupus erythematosus27
Timosaponin BII improved osteoporosis caused by hyperglycemia through promoting autophagy of osteoblasts via suppressing the mTOR/NFκB signaling pathway27
Host/microbiota interactions-derived tryptophan metabolites modulate oxidative stress and inflammation via aryl hydrocarbon receptor signaling27
High glucose-induced PRDX3 acetylation contributes to glucotoxicity in pancreatic β-cells: Prevention by Teneligliptin27
Antioxidant function of phytocannabinoids: Molecular basis of their stability and cytoprotective properties under UV-irradiation27
Myricetin prevents high molecular weight Aβ1-42 oligomer-induced neurotoxicity through antioxidant effects in cell membranes and mitochondria27
Mitochondria-targeted prooxidant effects of betulinic acid conjugated with delocalized lipophilic cation F1627
The photodynamic and direct actions of methylene blue on mitochondrial energy metabolism: A balance of the useful and harmful effects of this photosensitizer27
Enhanced defense against ferroptosis ameliorates cognitive impairment and reduces neurodegeneration in 5xFAD mice27
Lipid metabolism and oxidative stress in HPV-related cancers27
Antioxidant supplementation, redox deficiencies and exercise performance: A falsification design27
The neuroprotective effects of intermittent fasting on brain aging and neurodegenerative diseases via regulating mitochondrial function26
Genetic elucidation of hydrogen signaling in plant osmotic tolerance and stomatal closure via hydrogen sulfide26
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