OOIR: Observatory of International Research

Papers

(The median citation count of Autoimmunity is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
CAFs-released exosomal CREB1 promotes cell progression and immune evasion in thyroid cancer via the positive regulation of CCL20	34
Circ_0110251 overexpression alleviates IL-1β-induced chondrocyte apoptosis and extracellular matrix degradation by regulating miR-3189-3p/SPRY1 axis in osteoarthritis	33
Sodium propionate improves rheumatoid arthritis by inhibiting survivin mediated proliferation of fibroblast like synoviocytes by promoting miR-140-5p	31
Paeoniflorin improves autoimmune myocarditis in young rat by inhibiting CXCR5 to reduce follicular helper T cells	31
HERC6 is upregulated in peripheral blood mononuclear cells of patients with systemic lupus erythematosus and promotes the disease progression	24
Circ_0006944 aggravates LPS-induced HK2 cell injury via modulating miR-205-5p/UBL4A pathway	22
Identification of a circRNA-miRNA-mRNA network to explore the effects of circRNAs on renal injury in systemic lupus erythematosus	22
Identification of prognostic biomarkers of breast cancer based on the immune-related gene module	20
Prognostic characteristics of T-cell mediated cell killing-related genes in lung adenocarcinoma	20
DNA polymerase ζ suppresses the radiosensitivity of glioma cells by regulating the PI3K/AKT/mTOR pathway	19
Circ-UQCRC2 aggravates lipopolysaccharide-induced injury in human bronchial epithelioid cells via targeting miR-495-3p/MYD88-mediated inflammatory response and oxidative stress	18
Zinc finger protein 189 promotes the differentiation of lamina propria T helper 17.1 cells in dextran sulfate sodium-induced colitis	18
LncRNA CALML3-AS1 regulates chondrocyte apoptosis by acting as a sponge for miR-146a	16
LncRNA FOXD2-AS1 promotes cell proliferation and invasion of fibroblast-like synoviocytes by regulation of miR-331-3p/PIAS3 pathway in rheumatoid arthritis	16
Deciphering distinct pathogenic mechanisms of ankylosing spondylitis and systemic sclerosis via shared biomarkers ZSWIM6 and CCL3L3: Insights from an integrative bioinformatics approach	16
LncRNA CRNDE inhibits cardiomyocytes apoptosis by YAP1 in myocardial ischaemia/reperfusion injury	16
MicroRNA-340-5p inhibits endothelial apoptosis, inflammatory response, and pro-coagulation by targeting KDM4C in anti-neutrophil cytoplasmic antibody (ANCA)-mediated glomerulonephritis through activat	15
Abnormal lower expression of GPR183 in peripheral blood T and B cell subsets of systemic lupus erythematosus patients	14
HLA-transgenic mouse models to study autoimmune central nervous system diseases	13
The emerging role of the hedgehog signaling pathway in immunity response and autoimmune diseases	13
Identification the role of necroptosis in rheumatoid arthritis by WGCNA network	13
IL-4 polymorphisms (rs2227284, rs2243267, and rs2243270) are associated with reduced risk of rheumatoid arthritis	13
Alteration of reactive oxygen species master transcription factor Nrf2 in keratinocytes exposed to monoclonal pathogenic antibody AK23 against desmoglein-3 in pemphigus vulgaris	13
Type B thymomas in patients with myasthenia gravis display a distinctive pattern of αβ TCR and IL-7 receptor α expression on CD4 ⁺ CD8 ⁺	13
The prevalence and role of functional autoantibodies to angiotensin-converting-enzyme-2 in patients with systemic sclerosis	13

Knockdown of circ-PRKCH alleviates IL-1β-treated chondrocyte cell phenotypic changes through modulating miR-502-5p/ADAMTS5 axis	12
Immunoenhancement activity of Bletilla striata polysaccharide through MAPK and NF-κB signalling pathways in vivo and in vitro	12
CircNRIP1 promotes proliferation, migration and phenotypic switch of Ang II-induced HA-VSMCs by increasing CXCL5 mRNA stability via recruiting IGF2BP1	12
Innovate therapeutic targets for autoimmune diseases: insights from proteome-wide mendelian randomization and Bayesian colocalization	11
SARS-CoV-2 spike-specific regulatory T cells (Treg) expand and develop memory in vaccine recipients suggesting a role for immune regulation in preventing severe symptoms in COVID-19	11
KLF2 reduces dexamethasone-induced injury to growth plate chondrocytes by inhibiting the Runx2-mediated PI3K/AKT and ERK signalling pathways	11
Endonuclease G promotes preeclampsia by regulating the Wnt signaling pathway	11
Sema3A inactivates the ERK/JNK signalling pathways to alleviate inflammation and oxidative stress in lipopolysaccharide-stimulated rat endothelial cells and lung tissues	11
Down-regulation of KLF9 ameliorates LPS-caused acute lung injury and inflammation in mice via reducing GSDMD expression	10
Effects of Apelin on the fibrosis of retinal tissues and Müller cells in diabetes retinopathy through the JAK2/STAT3 signalling pathway	10
A novel circRNA, circRACGAP1, hampers the progression of systemic lupus erythematosus via miR-22-3p-mediated AKT signalling	10
Unveiling causal pathways in autoimmune diseases: a multi-omics approach	10
Knockdown of MKL1 ameliorates oxidative stress-induced chondrocyte apoptosis and cartilage matrix degeneration by activating TWIST1-mediated PI3K/AKT signaling pathway in rats	10
Gbp3 is associated with the progression of lupus nephritis by regulating cell proliferation, inflammation and pyroptosis	10
Gastrin producing syngeneic mesenchymal stem cells protect non-obese diabetic mice from type 1 diabetes	10
Circ_0016347 modulates proliferation, migration, invasion, cell cycle, and apoptosis of osteosarcoma cells via the miR-661/IL6R axis	10
SLAMF8 promotes the proliferation and migration of synovial fibroblasts by regulating the ERK/MMPs signalling pathway	9
High throughput multiplex immunoassays stratify patients according to symptom burden across the anti-Ro positive systemic autoimmune rheumatic disease spectrum	9
LncRNA XIST is involved in rheumatoid arthritis fibroblast-like synoviocytes by sponging miR-126-3p via the NF-κB pathway	9
Systemic lupus erythematosus is associated with the risk of coeliac disease: a Mendelian randomisation study	9
Effects of autoimmune abnormalities on fertility and placental morphology in mice	9
MiR-146b-5p targets IFI35 to inhibit inflammatory response and apoptosis via JAK1/STAT1 signalling in lipopolysaccharide-induced glomerular cells	9
The crosstalk between ferroptosis and autophagy in cancer	9
FOXO3 as a potential diagnostic biomarker for autophagy in rheumatoid arthritis: A bioinformatics study	9
Short interruptions of TNF-inhibitor treatment can be associated with treatment failure in patients with immune-mediated diseases	9
Autoimmune inflammatory reactions triggered by the COVID-19 genetic vaccines in terminally differentiated tissues	8
LncRNA LINC00707 serves as a sponge of miR-382-5p to alleviate lipopolysaccharide (LPS)-induced WI-38 cell injury through upregulating NKAP in infantile pneumonia	8
Potential significance of changes in serum levels of IL-17, TNF-α and DKK-1 in the progression of the rheumatoid arthritis	8
COVID-19: captures iron and generates reactive oxygen species to damage the human immune system	8
Contribution of DNA methylation to the pathogenesis of Sjögren's syndrome: A review	8
Berberine inhibits the development of endometrial cancer through circ_ZNF608/miR-377-3p/COX2 axis	8
CircFLNA/miR-214 modulates regulatory T cells by regulating PD-1 in acute lung injury induced by sepsis	8
Drug repurposing for rheumatoid arthritis: Identification of new drug candidates via bioinformatics and text mining analysis	8
Circ_0036490 and DKK1 competitively bind miR-29a to promote lipopolysaccharides-induced human gingival fibroblasts injury	8
The onset of de novo autoantibodies in healthcare workers after mRNA based anti-SARS-CoV-2 vaccines: a single centre prospective follow-up study	8
Circular RNA circZNF652 is overexpressed in osteoarthritis and positively regulates LPS-induced apoptosis of chondrocytes by upregulating PTEN	8
Dysregulation of tumour microenvironment driven by circ-TPGS2/miR-7/TRAF6/NF-κB axis facilitates breast cancer cell motility	8
Astragaloside IV promotes the pyroptosis of airway smooth muscle cells in childhood asthma by suppressing HMGB1/RAGE axis to inactivate NF-κb pathway	7
Subchronic intranasal lipopolysaccharide exposure induces pulmonary autoimmunity and glomerulonephritis in NZBWF1 mice	7
KISS-1 knockdown inhibits cell growth, migration, and invasion in HTR-8/SVneo cells by regulating the GRP54-mediated PI3K/AKT signaling pathway	7
The role of NLRP3 inflammasome in the pathogenesis of rheumatic disease	7
The role of NLRP3 inflammasome in type 2 inflammation related diseases	7
Increased IgD and CD27 Double Negative (DN) B cell population in pediatric onset autoimmune hepatitis	7
Progress in the field of animal models of antiphospholipid syndrome	7
BML-111 alleviates inflammatory response of alveolar epithelial cells via miR-494/Slit2/Robo4 signalling axis to improve acute lung injury	7
GADD45B predicts lung squamous cell carcinoma survival and impacts immune infiltration, and T cell exhaustion	7
Mitochondria as a key player in systemic lupus erythematosus	7
Novel peripheral blood mononuclear cell mRNA signature for IFN-beta therapy responsiveness prediction in multiple sclerosis	7
Partial long-term clinical improvement after a BCG challenge in systemic lupus erythematosus-prone mice	7
PD-1 gene polymorphisms and thyroid expression of PD-1 ligands differ between Graves’ and Hashimoto’s diseases	6

Characterization of IL-10-producing regulatory B cells in thymoma	6
Exosomal miR-132-3p from mesenchymal stem cells alleviated LPS-induced acute lung injury by repressing TRAF6	6
Highly-expressed circ_0129657 inhibits proliferation as well as promotes apoptosis and inflammation in HBMECs after oxygen-glucose deprivation via miR-194-5p/GMFB axis	6
MEOX2 serves as a novel biomarker associated with macrophage infiltration in oesophageal squamous cell carcinoma and other digestive system carcinomas	6
HSC70 is a novel binding partner involved in the capture of immunoglobulins on B cells in the NOD mouse	6
microRNA-130b-3p delivery by mesenchymal stem cells-derived exosomes confers protection on acute lung injury	6
Circ_0114428 promotes proliferation, fibrosis and EMT process of high glucose-induced glomerular mesangial cells through regulating the miR-185-5p/SMAD3 axis	6
Modulation of miR-382-5p reduces apoptosis of myocardial cells after acute myocardial infarction	6
microRNA-17-5p downregulation inhibits autophagy and myocardial remodelling after myocardial infarction by targeting STAT3	6
Effect of Agmatine on a mouse model of allergic airway inflammation: A comparative study	5
Hypoxic tumour-derived exosomal miR-1225-5p regulates M2 macrophage polarisation via toll-like receptor 2 to promote ovarian cancer progress	5
Serum sirtuin-1 a potential marker in the diagnosis of rheumatoid arthritis	5
Aberrant microRNA expression in B lymphocytes from patients with primary warm autoimmune haemolytic anaemia	5
LncRNA DGCR5/miR-204-5p/SRSF7 axis regulates PDGF-BB-induced proliferation and migration of airway smooth muscle cells with potential role in asthma	5
Single-cell analysis with childhood and adult systemic lupus erythematosus	5
Mitochondrial autophagy-related gene signatures associated with myasthenia gravis diagnosis and immunity	5
Correction	5
Transient B-cell depletion and regulatory T-cells mediation in combination with adenovirus mediated IGF-1 prevents and reverses autoimmune diabetes in NOD mice	5
DNA methylation differences within INS , PTPN22 and IL2RA promoters in lymphocyte subsets in children with	5
Identified potential biomarkers may predict primary nonresponse to infliximab in patients with ulcerative colitis	5
Analysis of circulating immune cells in patients with rheumatoid arthritis and positive for hashimoto thyroiditis antibodies	5
TGFB1+869 T > C (rs1800470) variant is independently associated with susceptibility, laboratory activity, and TGF-β1 in patients with systemic lupus erythematosus	5
LncRNA ZNF667-AS1 alleviates rheumatoid arthritis by sponging miR-523-3p and inactivating the JAK/STAT signalling pathway	5
High-throughput autoantibody profiling of different stages of Schistosomiasis japonica	5
Circ_0035796 depletion inhibits transforming growth factor-β1-induced pulmonary fibrosis in a miR-150-5p/L1CAM-dependent manner	5
Circ_0088036 facilitates the proliferation and inflammation and inhibits the apoptosis of fibroblast-like synoviocytes through targeting miR-326/FZD4 axis in rheumatoid arthritis	5
Identification of TXN and F5 as novel diagnostic gene biomarkers of the severe asthma based on bioinformatics and machine learning analysis	5
CircTRHDE knockdown protects WI-38 cells against LPS-induced inflammatory injury	5
Circ_0005714/miR-223-3p/ADAM9 regulatory axis affects proliferation, migration, invasion, and angiopoiesis in trophoblast cells	5
Associations between IL-23R gene polymorphism (rs10889677 A/C) and ankylosing spondylitis and rheumatoid arthritis susceptibility: A meta-analysis with trial sequential analysis	4
Quercetin improves the imbalance of Th1/Th2 cells and Treg/Th17 cells to attenuate allergic rhinitis	4
LncRNA HOTAIR inhibits the progression of fibroblast-like synoviocytes by sponging miRNA-106b-5p in rheumatoid arthritis	4
iTreg cells-secreted IL10 alleviates lupus nephritis through inactivating lncRNA HAR1A transcription to suppress SMARCD1-mediated iNOS activation	4
OSR1 suppresses acute myeloid leukaemia cell proliferation by inhibiting LGR5-mediated JNK signalling	4
CLDN1 silencing suppresses the proliferation and migration of airway smooth muscle cells by modulating MMP14	4
TMEM164 promotes ferroptosis by selectively mediating ATG5-dependent autophagosome formation to inhibit the progression of LUAD	4
MiR-361-5p promotes proliferation and inhibits apoptosis of fibroblast-like synoviocytes via targeting ZBTB10 in rheumatoid arthritis	4
MiR-144-3p induced by SP1 promotes IL-1β-induced pyroptosis in chondrocytes via PTEN/PINK1/Parkin axis	4
Dysregulated CXCL12 expression in osteoblasts promotes B-lymphocytes preferentially homing to the bone marrow in MRL/lpr mice	4
The utility of immunoglobulin A/complement 3 and immunoglobulin G/immunoglobulin M ratios in the assessment of disease activation in patients with Behçet disease	4
Progesterone decreased indoleamine 2,3-dioxygenase 1(IDO1) expression in early pregnancy chorionic villi and decidua	4
Bulk T-cell receptor sequencing confirms clonality in obstetric antiphospholipid syndrome and may as a potential biomarker	4
LDHA-induced histone lactylation mediates the development of osteoarthritis through regulating the transcription activity of TPI1 gene	4
Identification of SAA1 as a prognostic biomarker associated with immune infiltration in glioblastoma	4
SChLAP1 contributes to non-small cell lung cancer cell progression and immune evasion through regulating the AUF1/PD-L1 axis	4
IDO1-mediated M2 macrophage polarization alleviates the progression of ankylosing spondylitis	4
The lncRNA PVT1/miR-590-5p/FSTL1 axis modulates the proliferation and migration of airway smooth muscle cells in asthma	4
Natural isoaspartyl protein modification of ZAP70 alters T cell responses in lupus	4
Genome-wide identification of cell type-specific susceptibility genes for Juvenile dermatomyositis through the analysis of N ⁶ -methyladenosine-associated SNPs	4