OOIR: Observatory of International Research

Papers

(The median citation count of Autoimmunity is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
Sodium propionate improves rheumatoid arthritis by inhibiting survivin mediated proliferation of fibroblast like synoviocytes by promoting miR-140-5p	51
Antigen presentation-related protein APOL3 promotes anti-tumor T cell immunity and suppresses melanoma cell growth in mice	49
Alteration of reactive oxygen species master transcription factor Nrf2 in keratinocytes exposed to monoclonal pathogenic antibody AK23 against desmoglein-3 in pemphigus vulgaris	34
Endonuclease G promotes preeclampsia by regulating the Wnt signaling pathway	26
The emerging role of the hedgehog signaling pathway in immunity response and autoimmune diseases	25
CAFs-released exosomal CREB1 promotes cell progression and immune evasion in thyroid cancer via the positive regulation of CCL20	25
Characterization of IL-10-producing regulatory B cells in thymoma	23
Innovate therapeutic targets for autoimmune diseases: insights from proteome-wide mendelian randomization and Bayesian colocalization	23
MiR-146b-5p targets IFI35 to inhibit inflammatory response and apoptosis via JAK1/STAT1 signalling in lipopolysaccharide-induced glomerular cells	22
Mitochondria as a key player in systemic lupus erythematosus	21
Subchronic intranasal lipopolysaccharide exposure induces pulmonary autoimmunity and glomerulonephritis in NZBWF1 mice	19
MiR-361-5p promotes proliferation and inhibits apoptosis of fibroblast-like synoviocytes via targeting ZBTB10 in rheumatoid arthritis	19
Increased IgD and CD27 Double Negative (DN) B cell population in pediatric onset autoimmune hepatitis	19
Identified potential biomarkers may predict primary nonresponse to infliximab in patients with ulcerative colitis	19
Associations between IL-23R gene polymorphism (rs10889677 A/C) and ankylosing spondylitis and rheumatoid arthritis susceptibility: A meta-analysis with trial sequential analysis	16
Long non-coding RNA LINC00265 promotes proliferation, apoptosis, and inflammation of chondrocytes in osteoarthritis by sponging miR-101-3p	16
MiR-300 promotes the proliferation, migration and invasion of fibroblast-like synoviocytes in rheumatoid arthritis by targeting IL-37	16
OSR1 suppresses acute myeloid leukaemia cell proliferation by inhibiting LGR5-mediated JNK signalling	16
Sex-specific differences in SLE – Significance in the experimental setting of inflammation and kidney damage in MRL-Fas ^lpr mice	15
YTHDF1 activates FBW7 transcription by regulating m ⁶ A-dependent FOXO1 to facilitate inflammatory response in ulcerative colitis-like model	15
The association of 25(OH)D, interleukin-4, interleukin-5, and interleukin-13 levels with the burden of soil-transmitted helminth infection in stunted children aged 24–59 months	15
A novel circ_0099999/miR-330-5p/FSCN1 ceRNA crosstalk in pancreatic cancer	15
Inhibition of LncRNA SNHG14 protects chondrocyte from injury in osteoarthritis via sponging miR-137	14
Circ_0007535 upregulates TGFBR1 to promote pulmonary fibrosis in TGF-β1-treated lung fibroblasts via sequestering miR-18a-5p	14
Identification and validation of susceptibility modules and hub genes in polyarticular juvenile idiopathic arthritis using WGCNA and machine learning	14

Identification of new hub- ferroptosis-related genes in Lupus Nephritis	13
Knockdown of circ-PRKCH alleviates IL-1β-treated chondrocyte cell phenotypic changes through modulating miR-502-5p/ADAMTS5 axis	13
Identification of mite-specific eosinophils in the colon of patients with ulcerative colitis	13
Expression of the miR-9-5p, miR-125b-5p and its target gene NFKB1 and TRAF6 in childhood-onset systemic lupus erythematosus (cSLE)	13
RGS7 silence protects palmitic acid-induced pancreatic β-cell injury by inactivating the chemokine signaling pathway	13
Effect of FcRn antagonism on protective antibodies and to vaccines in IgG-mediated autoimmune diseases pemphigus and generalised myasthenia gravis	13
Lactylation-related genes serve as potential markers for the diagnosis and immune infiltration in rheumatoid arthritis	13
Abnormal lower expression of GPR183 in peripheral blood T and B cell subsets of systemic lupus erythematosus patients	12
IL-4 polymorphisms (rs2227284, rs2243267, and rs2243270) are associated with reduced risk of rheumatoid arthritis	12
Type B thymomas in patients with myasthenia gravis display a distinctive pattern of αβ TCR and IL-7 receptor α expression on CD4 ⁺ CD8 ⁺	12
Circ-UQCRC2 aggravates lipopolysaccharide-induced injury in human bronchial epithelioid cells via targeting miR-495-3p/MYD88-mediated inflammatory response and oxidative stress	12
Identification of prognostic biomarkers of breast cancer based on the immune-related gene module	12
Deciphering distinct pathogenic mechanisms of ankylosing spondylitis and systemic sclerosis via shared biomarkers ZSWIM6 and CCL3L3: Insights from an integrative bioinformatics approach	11
Short interruptions of TNF-inhibitor treatment can be associated with treatment failure in patients with immune-mediated diseases	11
KISS-1 knockdown inhibits cell growth, migration, and invasion in HTR-8/SVneo cells by regulating the GRP54-mediated PI3K/AKT signaling pathway	11
Immunoenhancement activity of Bletilla striata polysaccharide through MAPK and NF-κB signalling pathways in vivo and in vitro	11
Autoimmune inflammatory reactions triggered by the COVID-19 genetic vaccines in terminally differentiated tissues	11
A novel circRNA, circRACGAP1, hampers the progression of systemic lupus erythematosus via miR-22-3p-mediated AKT signalling	11
GADD45B predicts lung squamous cell carcinoma survival and impacts immune infiltration, and T cell exhaustion	11
Circ_0005714/miR-223-3p/ADAM9 regulatory axis affects proliferation, migration, invasion, and angiopoiesis in trophoblast cells	10
High throughput multiplex immunoassays stratify patients according to symptom burden across the anti-Ro positive systemic autoimmune rheumatic disease spectrum	10
Novel peripheral blood mononuclear cell mRNA signature for IFN-beta therapy responsiveness prediction in multiple sclerosis	10
Serum sirtuin-1 a potential marker in the diagnosis of rheumatoid arthritis	9
IDO1-mediated M2 macrophage polarization alleviates the progression of ankylosing spondylitis	9
Genome-wide identification of cell type-specific susceptibility genes for Juvenile dermatomyositis through the analysis of N ⁶ -methyladenosine-associated SNPs	9
Identification of TXN and F5 as novel diagnostic gene biomarkers of the severe asthma based on bioinformatics and machine learning analysis	9
microRNA-17-5p downregulation inhibits autophagy and myocardial remodelling after myocardial infarction by targeting STAT3	9
Correction	9
CircCDK14 ameliorates interleukin-1β-induced chondrocyte damage by the miR-1183/KLF5 pathway in osteoarthritis	9
Exosomal miR-132-3p from mesenchymal stem cells alleviated LPS-induced acute lung injury by repressing TRAF6	9
Identifying the potential therapeutic targets of tertiary lymphoid structure in IgA nephropathy based on bioinformatics	9
PLD1 knockdown reduces metastasis and inflammation of fibroblast-like synoviocytes in rheumatoid arthritis by modulating NF-κB and Wnt/β-catenin pathways	9
Circ_0114428 promotes proliferation, fibrosis and EMT process of high glucose-induced glomerular mesangial cells through regulating the miR-185-5p/SMAD3 axis	9
OGT-induced O-GlcNAcylation of NEK7 protein aggravates osteoarthritis progression by enhancing NEK7/NLRP3 axis	8
HERC6 is upregulated in peripheral blood mononuclear cells of patients with systemic lupus erythematosus and promotes the disease progression	8
A whole blood-based functional assay to characterize immunoglobulin A effector functions	8
Knockdown of NEK7 alleviates anterior cruciate ligament transection osteoarthritis (ACLT)-induced knee osteoarthritis in mice via inhibiting NLRP3 activation	8
Circ_0011058 alleviates RA pathology through the circ_0011058/miR-335-5p/CUL4B signal axis	8
Circulating interleukin-27 is associated with the risk of chronic periodontitis and allergic rhinitis: A Mendelian randomization analysis	8
Isorhynchophylline attenuates proliferation and migration of synovial fibroblasts via the FOXC1/β-catenin axis	8
Unveiling causal pathways in autoimmune diseases: a multi-omics approach	8
Hsa_circ_0037128 aggravates high glucose-induced podocytes injury in diabetic nephropathy through mediating miR-31-5p/KLF9	8
Functional significance of the rare rs35667974 IFIH1 gene polymorphism, associated with multiple autoimmune diseases, using a structural biological approach	8
Circ_0114427 promotes LPS-induced septic acute kidney injury by modulating miR-495-3p/TRAF6 through the NF-κB pathway	8
LncRNA XIST restrains the activation of Müller cells and inflammation in diabetic retinopathy via stabilizing SIRT1	8
Effects of Apelin on the fibrosis of retinal tissues and Müller cells in diabetes retinopathy through the JAK2/STAT3 signalling pathway	8
CircVMA21 ameliorates lipopolysaccharide (LPS)-induced HK-2 cell injury depending on the regulation of miR-7-5p/PPARA	8
The role of gut microbiota in different murine models of systemic lupus erythematosus	8
Increasing expression of dual-specificity phosphatase 12 mitigates oxygen-glucose deprivation/reoxygenation-induced neuronal apoptosis and inflammation through inactivation of the ASK1-JNK/p38 MAPK pa	8
CircNRIP1 promotes proliferation, migration and phenotypic switch of Ang II-induced HA-VSMCs by increasing CXCL5 mRNA stability via recruiting IGF2BP1	7

Potential significance of changes in serum levels of IL-17, TNF-α and DKK-1 in the progression of the rheumatoid arthritis	7
Correction	7
LncRNA LINC00707 serves as a sponge of miR-382-5p to alleviate lipopolysaccharide (LPS)-induced WI-38 cell injury through upregulating NKAP in infantile pneumonia	7
Circ_0088036 facilitates the proliferation and inflammation and inhibits the apoptosis of fibroblast-like synoviocytes through targeting miR-326/FZD4 axis in rheumatoid arthritis	7
Astragaloside IV promotes the pyroptosis of airway smooth muscle cells in childhood asthma by suppressing HMGB1/RAGE axis to inactivate NF-κb pathway	7
Progress in the field of animal models of antiphospholipid syndrome	7
The role of NLRP3 inflammasome in the pathogenesis of rheumatic disease	7
LncRNA HOTAIR inhibits the progression of fibroblast-like synoviocytes by sponging miRNA-106b-5p in rheumatoid arthritis	7
Mitochondrial autophagy-related gene signatures associated with myasthenia gravis diagnosis and immunity	6
Natural isoaspartyl protein modification of ZAP70 alters T cell responses in lupus	6
Patients with dermatomyositis shared partially similar transcriptome signature with COVID-19 infection	6
LncRNA RP5-857K21.7 inhibits PDGF-BB-induced proliferation and migration of airway smooth muscle cells through the miR-508-3p/PI3K/AKT/mTOR axis	6
Quercetin improves the imbalance of Th1/Th2 cells and Treg/Th17 cells to attenuate allergic rhinitis	6
LncRNA OIP5-AS1/miR-410-3p/Wnt7b axis promotes the proliferation of rheumatoid arthritis fibroblast-like synoviocytes via regulating the Wnt/β-catenin pathway	6
LDHA-induced histone lactylation mediates the development of osteoarthritis through regulating the transcription activity of TPI1 gene	6
Mesenchymal stem cells-derived exosomes ameliorate high glucose and lipopolysaccharide-induced HPMECs injury through the Nrf2/HO-1 pathway	6
Analysis of circulating immune cells in patients with rheumatoid arthritis and positive for hashimoto thyroiditis antibodies	6
High-throughput autoantibody profiling of different stages of Schistosomiasis japonica	6
Role of oxidative stress in pathophysiology of rheumatoid arthritis: insights into NRF2-KEAP1 signalling	6
MiR-526b-3p enhances sensitivity of head and neck squamous cell carcinoma cells to radiotherapy via suppressing exosomal LAMP3-mediated autophagy	5
Knockdown of circ_0025908 inhibits proliferation, migration, invasion, and inflammation while stimulates apoptosis in fibroblast-like synoviocytes by regulating miR-650-dependent SCUBE2	5
LncRNA NEAT1 regulates MMP-16 by targeting miR-200a/b to aggravate inflammation in asthma	5
Research progress in the construction of animal models of autoimmune thyroiditis	5
Regulatory role of ceRNA network in B lymphocytes of patients with immune thrombocytopenia	5
Analysis and validation of diagnostic biomarkers and immune cell infiltration characteristics in Crohn’s disease by integrating bioinformatics and machine learning	5
Identification of macrophage-related molecular subgroups and risk signature in colorectal cancer based on a bioinformatics analysis	5
Gastrin producing syngeneic mesenchymal stem cells protect non-obese diabetic mice from type 1 diabetes	4
SARS-CoV-2 spike-specific regulatory T cells (Treg) expand and develop memory in vaccine recipients suggesting a role for immune regulation in preventing severe symptoms in COVID-19	4
Silencing of CircTRIM25/miR-138-5p/CREB1 axis promotes chondrogenesis in osteoarthritis	4
BML-111 alleviates inflammatory response of alveolar epithelial cells via miR-494/Slit2/Robo4 signalling axis to improve acute lung injury	4
Partial long-term clinical improvement after a BCG challenge in systemic lupus erythematosus-prone mice	4
Systemic lupus erythematosus is associated with the risk of coeliac disease: a Mendelian randomisation study	4
CircTRHDE knockdown protects WI-38 cells against LPS-induced inflammatory injury	4
DNA polymerase ζ suppresses the radiosensitivity of glioma cells by regulating the PI3K/AKT/mTOR pathway	4
Mechanism of Resveratrol on LPS/ATP-induced pyroptosis and inflammatory response in HT29 cells	4
Identification of a circRNA-miRNA-mRNA network to explore the effects of circRNAs on renal injury in systemic lupus erythematosus	4
Down-regulation of KLF9 ameliorates LPS-caused acute lung injury and inflammation in mice via reducing GSDMD expression	4
The role of NLRP3 inflammasome in type 2 inflammation related diseases	4
Drug repurposing for rheumatoid arthritis: Identification of new drug candidates via bioinformatics and text mining analysis	4
microRNA-130b-3p delivery by mesenchymal stem cells-derived exosomes confers protection on acute lung injury	4
Gbp3 is associated with the progression of lupus nephritis by regulating cell proliferation, inflammation and pyroptosis	4
HLA-transgenic mouse models to study autoimmune central nervous system diseases	4
SMURF1 activates the cGAS/STING/IFN-1 signal axis by mediating YY1 ubiquitination to accelerate the progression of lupus nephritis	4
Paeoniflorin improves autoimmune myocarditis in young rat by inhibiting CXCR5 to reduce follicular helper T cells	4
The onset of de novo autoantibodies in healthcare workers after mRNA based anti-SARS-CoV-2 vaccines: a single centre prospective follow-up study	4
The crosstalk between ferroptosis and autophagy in cancer	4
Circ_0036490 and DKK1 competitively bind miR-29a to promote lipopolysaccharides-induced human gingival fibroblasts injury	4
Circ_0035796 depletion inhibits transforming growth factor-β1-induced pulmonary fibrosis in a miR-150-5p/L1CAM-dependent manner	4