Immunopharmacology and Immunotoxicology

Papers
(The TQCC of Immunopharmacology and Immunotoxicology is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)
ArticleCitations
In vitro anti-tumor activities of a novel recombinant immunotoxin targeting differentially overexpressed Leucine-rich repeat-containing G-protein-coupled receptor 5 in cervical canc50
Assessing the effectiveness of camrelizumab plus anti-angiogenesis drug for the treatment of advanced liver cancer: a single‑center retrospective study43
Moscatilin protects concanavalin A-induced autoimmune liver disease in mice29
Inhibition of long-lived plasma cells, a critical role for Telitacicept treatment to systemic lupus erythematosus24
Extracellular vesicle-derived LINC00511 promotes glycolysis and mitochondrial oxidative phosphorylation of pancreatic cancer through macrophage polarization by microRNA-193a-3p-dependent regulation of23
Leukoreduced PRP enhanced proliferation and ECM production yet inhibited senescence, inflammation, and multi-differentiation potential of AFSCs by downregulating HMGB122
Galantamine supplementation and rheumatoid arthritis: a systematic review of current research and molecular mechanisms22
Sirtinol, a SIRT1 inhibitor, inhibits the EMT and metastasis of 4T1 breast cancer cells and impacts the tumor microenvironment22
Corynoline ameliorates dextran sulfate sodium-induced colitis in mice by modulating Nrf2/NF-κB pathway21
Beta-sitosterol alleviates inflammatory culprits and disease severity in arthritic irradiated rat’s model: role of brain-spleen axis21
Prospective therapeutic targets and recent advancements in the treatment of inflammatory bowel disease20
Gastrodin ameliorates Concanavalin A-induced acute hepatitis via the IL6/JAK2/STAT3 pathway20
An overview of the current advances in the treatment of inflammatory diseases using mesenchymal stromal cell secretome19
Withaferin A suppressed hepatocellular carcinoma progression through inducing IGF2BP3/FOXO1/JAK2/STAT3 pathway-mediated ROS production17
Sevoflurane induces cognitive dysfunction by modulating PER2 methylation to block AKT pathway-suppressed NLRP3 inflammatory vesicle in microglia17
Aryl-Cyclohexanone as a potential CB2 agonist: in vitro and in silico evidence in inflammatory modulation17
Cancer-associated immune cells and their modulation by melatonin16
Role of oncostatin M and its receptor in the inflammatory pathogenesis of graves’ orbitopathy16
Protective effect of pregabalin on renal and renal endothelial damage in sepsis induced by lipopolysaccharide16
Systematic review of the efficacy and safety of lenvatinib in various solid tumors16
Correction16
Neutrophil Extracellular Traps (NET) and SARS-CoV-216
Silver nanoparticle–conjugated pyrimidine-based BN6 methanimine derivative improves DSS-induced inflammatory bowel disease in zebrafish16
Monotropein alleviates acute pulmonary embolism in rats by inhibiting the NF-κB pathway16
Sulforaphane alleviates LPS-induced inflammatory injury in ARPE-19 cells by repressing the PWRN2/NF-kB pathway15
mTORC1 inhibition may improve T lymphocytes affected by aging15
Immunotherapeutic potentials of carnosol against lipopolysaccharides-induced acute inflammatory reactions in White Swiss albino mice15
Sirt1/Nrf2/TNFα; TLR4/Myd88/NF-κB signaling pathways are involved in mediating hepatoprotective effect of bupropion in rat model of myocardial infarction15
Dapagliflozin alleviates thioacetamide induced-liver fibrosis in rats via controlling the Nrf2/HO-1 and TLR4/TGF-β1/PI3K signaling pathways15
Correction14
Thymosin α1 improves the outcomes of patients with hepatitis B virus-related acute-on-chronic liver failure by restoring immune balance14
Hydroxychloroquine ameliorates immune functionality and intestinal flora disorders of IgA nephropathy by inhibition of C1GALT1/Cosmc pathway13
Baicalin suppresses interleukin-1β-induced apoptosis, inflammatory response, oxidative stress, and extracellular matrix degradation in human nucleus pulposus cells13
Investigation of the effect of IFN-γ/TNF-α-treated mesenchymal stem cells on Th9- and Treg cell-related parameters in a mouse model of ovalbumin-induced allergic asthma13
Losartan ameliorates premature ovarian failure by regulation of the Sirti1/NF-κB pathway in female albino rats13
Celecoxib alleviates the DSS-induced ulcerative colitis in mice by enhancing intestinal barrier function, inhibiting ferroptosis and suppressing apoptosis13
SDH5 down-regulation mitigates the damage of osteoporosis via inhibiting the MyD88/NF-κB signaling pathway13
Molecular mechanisms mediate roflumilast protective effect against isoprenaline-induced myocardial injury12
Selective and effective suppression of pancreatic cancer through MNK inhibition12
The effect of Vortioxetine on the NLRP3 pathway and microglial activity in the prefrontal cortex in an experimental model of depression12
Anticolitis effect of febuxostat. The imperative role of NLRP-3/Caspase-1/IL-1β pathway via histopathological, immunohistochemical and biochemical approach12
Astragaloside IV restores Th17/Treg balance via inhibiting CXCR4 to improve chronic obstructive pulmonary disease12
Rituximab induces a flare-up of activated neutrophil extracellular traps under in vitro conditions12
CircRNA circ-PDCD11 is highly expressed in lung large-cell carcinoma and predicts poor survival12
Thymic stromal lymphopoietin levels after allogeneic hematopoietic stem cell transplantation11
Association between serum baseline C1q and IgG levels and the efficacy of combined immunotherapy in patients with esophageal squamous cell carcinoma: a retrospective study11
Two flavonoids, baicalein and naringin, are effective as anti-inflammatory and anti-oxidant agents in a rat model of polymicrobial sepsis11
Correction10
Forkhead box A1 induces angiogenesis through activation of the S100A8/p38 MAPK axis in cutaneous wound healing10
Cannabis sativa alleviates experimentally acetic acid- induced ulcerative colitis in rats: targeting CB1/SIRT/MAPK signaling pathways10
Cardioprotective effect of tofisopam against isoprenaline-induced myocardial infarction in rats via modulation of NLRP3\IL-1β\caspase-1 pathway10
IGF2BP3 aggravates lung adenocarcinoma progression by modulation of PI3K/AKT signaling pathway10
Glucocorticoid receptor signaling: crosstalk with inflammation10
T-cell metabolism in rheumatoid arthritis: focus on mitochondrial and lysosomal dysfunction9
Leptin/lipopolysaccharide-treated dendritic cell vaccine improved cellular immune responses in an animal model of breast cancer9
Nodakenin attenuates cerebral ischemia–reperfusion injury by modulating the PI3K/AKT/NF-κB signaling pathway9
Gigantol protects retinal pigment epithelial cells against high glucose-induced apoptosis, oxidative stress and inflammation by inhibiting MTDH-mediated NF-kB signaling pathway9
Occupational exposure to pesticides affects systemic cytokine profile and correlates with poor clinical prognosis in young women with breast cancer9
Galectin-1-producing mesenchymal stem cells restrain the proliferation of T lymphocytes from patients with systemic lupus erythematosus9
Expression of calcitonin gene-related peptide in atopic dermatitis and correlation with distress9
Role of EGF/ERK1/2/HO-1 axis in mediating methotrexate induced testicular damage in rats and the ameliorative effect of xanthine oxidase inhibitors9
Seasonal facial erythema in a patient with allergic rhinitis treated using a combination of tranilast and roxithromycin9
Decreasing REDD1 expression protects against high glucose-induced apoptosis, oxidative stress and inflammatory injury in podocytes through regulation of the AKT/GSK-3β/Nrf2 pathway9
Prognostic values of neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios in the early prediction of aluminum phosphide-poisoned patients’ outcomes9
Impact of interleukin-32α on T helper cell-related cytokines, transcription factors, and proliferation in patients with type 2 diabetes mellitus8
Investigating the therapeutic efficacy of physical exercise on tumor immunity in a mouse model of malignant colon cancer8
Endoplasmic reticulum stress is upregulated in inflammatory bowel disease and contributed TLR2 pathway-mediated inflammatory response8
Luteolin restored Treg/Th17 balance to ameliorate allergic rhinitis in a mouse model8
Kindlin-2 silencing promoted apoptosis and cell cycle arrest through the fas/FasL pathway in hepatocellular carcinoma8
Evaluation of the inhibitory effect of different molecular weights chitosan on MRGPRX2-mediated mast cell degranulation and the pseudo-allergic reaction8
Time to treat the climate and nature crisis as one indivisible global health emergency8
Targeting alpha 7 nicotinic acetylcholine receptors by galantamine alleviates doxorubicin-induced cardiotoxicity via modulation of PI3K/AKT, Bax/Bcl-2, a8
β-Sitosterol inhibits ovalbumin-induced asthma-related inflammation by regulating dendritic cells8
Wogonoside preserves against ischemia/reperfusion-induced myocardial injury by suppression of apoptosis, inflammation, and fibrosis via modulating Nrf2/HO-1 pathway8
Rituximab beyond oncology: targeting B-cell-mediated immunomodulatory therapy in neurodegenerative and neuropsychiatric disorders7
All- trans retinoic acid ameliorates S100-induced experimental autoimmune hepatitis by regulating the Treg/Th17 balance7
Nanocarriers for lung health: ameliorating inflammation and cell aging using flavonoid-based nano nutrients7
The anti-inflammatory effects of vitamin B6 on neuroinflammation and neuronal damage caused by 1,2-diacetylbenzene in BV2 microglial and sH-SY5Y cells7
Amygdalin alleviates atopic dermatitis-like skin inflammation via inhibition of Th2 immune responses7
Hydroxychloroquine exacerbates imiquimod-induced psoriasis-like dermatitis through stimulating overexpression of IL-6 in keratinocytes7
Therapeutic efficacy of tofacitinib in PDSAg-induced chronic experimental autoimmune uveitis in Wistar rat7
Vildagliptin attenuates doxorubicin-induced hepatotoxicity via activating Nrf2/HO-1 and SIRT1 and suppressing NF-κB signals in rats7
Reno-protective impact of diosmin and perindopril in amikacin-induced nephrotoxicity rat model: modulation of SIRT1/p53/C-FOS, NF-κB-p65, and keap-1/Nrf2/HO-1 signaling pathways7
Ascorbic acid and hydrocortisone synergistically inhibit septic organ injury via improving oxidative stress and inhibiting inflammation7
Efficacy and safety of the combined use of ipilimumab and nivolumab for melanoma patients with brain metastases: a systematic review and meta-analysis7
Icariin decreases cell proliferation and inflammation of rheumatoid arthritis-fibroblast like synoviocytes via GAREM1/MAPK signaling pathway7
Impact of Glucocorticoids on Interstitial Lung Disease: A Medical Information Mart for Intensive Care and Mendelian Randomization Study7
The protective effect of butylated hydroxytoluene and 3-hydroxytyrosol on food allergy in mice7
Fumaric acid per se and in combination with methotrexate arrests inflammation via moderating inflammatory and oxidative stress biomarkers in arthritic rats6
Tumor cells inhibit the activation of ILC2s through up-regulating PD-1 expression6
The dual potential of topical roflumilast: advancing psoriasis therapy and pioneering oral mucosal disease treatment6
The effect of vitamin C supplementation on favipiravir-induced oxidative stress and proinflammatory damage in livers and kidneys of rats6
Safety assessment of voclosporin: a real-world disproportionality analysis of the FAERS database6
microRNA-103a-3p promotes inflammation and fibrosis in nonalcoholic fatty liver disease by targeting HBP16
Investigation of the therapeutic potential of recombinant bispecific bivalent anti-PD-L1/VEGF nanobody in inhibition of angiogenesis6
α-Cyperone ameliorates depression in mammary gland hyperplasia and chronic unpredictable mild stress rat by regulating hormone, inflammation, and oxidative stress6
Vinpocetine mitigates methotrexate-induced duodenal intoxication by modulating NF-κB, JAK1/STAT-3, and RIPK1/RIPK3/MLKL signals6
Studying the effect of chronic toxicity of monosodium glutamate on interleukin-10 and interleukin-17 in albino Wistar rats6
Febuxostat attenuates cyclophosphamide-induced ovarian toxicity; role of TLR4/NFκB/NLRP3 signaling pathway in female wistar albino rats6
The anti-inflammatory activity and toxicological safety of synthetic chalcone derivatives in preclinical trials6
Sodium benzoate exacerbates hepatic oxidative stress and inflammation in lipopolysaccharide-induced liver injury in rats6
The therapeutic potential of jaceosidin: a comprehensive review of its effects on chronic diseases6
A Comparative Analysis of MSCs and Their Exosomes in Osteoarthritis Therapy: Complementary Roles and Clinical Translation6
Acute kidney injury associated with anti-PD-1 and anti-PD-L1 drugs: a meta-analysis of randomized clinical trials6
Breviscapine inhibits the proliferation and immune escape of diffuse large B-cell lymphoma cells by regulating JAK2/STAT3/PD-L1 pathway6
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