Neuropsychopharmacology

Papers
(The median citation count of Neuropsychopharmacology is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)
ArticleCitations
Role of neuropeptide neuromedin U in the nucleus accumbens shell in cocaine self-administration in male rats908
A new prism next to motherhood’s light: uncovering changes in neural function following childbirth402
Fentanyl-induced hyperalgesia and analgesic tolerance in male rats: common underlying mechanisms and prevention by a polyamine deficient diet388
ACNP 62nd Annual Meeting: Keyword Index224
Novel approaches to estimate prefrontal synaptic strength in vivo in humans: of relevance to depression, schizophrenia, and ketamine198
It’s about racism, not race: a call to purge oppressive practices from neuropsychiatry and scientific discovery185
Distinct roles of excitatory and inhibitory neurons in the medial prefrontal cortex in the expression and reconsolidation of methamphetamine-associated memory in male mice174
The National Institute on Drug Abuse Summer Research Internship Program: Building a Diverse National Scientific Workforce149
Using metabolic imaging to investigate neuromodulatory mechanisms of rTMS146
Correction to: Isoform-selective phosphoinositide 3-kinase inhibition ameliorates a broad range of fragile X syndrome-associated deficits in a mouse model144
Targeted and transient opening of the blood brain barrier in discrete neurocircuits and brain regions117
Delayed estrogen actions diminish food consumption without changing food approach, motor activity, or hypothalamic activation elicited by corticostriatal µ-opioid signaling113
Potentiation of AMPA receptors for rapid therapeutic gain in psychiatry has reached a new level of excitement98
Fetal behavior and gestational serotonin reuptake inhibitor exposure: relationships between behavior, drug dosage, plasma drug level, and a measure of drug bioeffect93
Gestational ethanol exposure impairs motor skills in female mice through dysregulated striatal dopamine and acetylcholine function90
Validation of a non-food or water motivated effort-based foraging task as a measure of motivational state in male mice90
Inhibition of striatal indirect pathway during second postnatal week leads to long-lasting deficits in motivated behavior89
ACNP 61st Annual Meeting: Poster Abstracts P541 – P80982
Prefrontal allopregnanolone mediates the adverse effects of acute stress in a mouse model of tic pathophysiology80
Sensitive period-regulating genetic pathways and exposure to adversity shape risk for depression79
Data-driven connectivity profiles relate to smoking cessation outcomes78
Pramipexole modulates fronto-subthalamic pathway in sequential working memory77
Hippocampus and amygdala fear memory engrams re-emerge after contextual fear relapse77
A double-blind, randomized controlled study of the effects of celecoxib on clinical symptoms and cognitive impairment in patients with drug-naïve first episode schizophrenia: pharmacogenetic impact of69
Parvalbumin interneuron mGlu5 receptors govern sex differences in prefrontal cortex physiology and binge drinking67
Altered neuronal activity in the ventromedial prefrontal cortex drives nicotine intake escalation66
The GABAA receptor modulator zolpidem augments hippocampal-prefrontal coupling during non-REM sleep66
Leveraging large-scale brain networks in rats to understand neurological and psychiatric disorders in humans65
Amplitude-determined seizure-threshold, electric field modeling, and electroconvulsive therapy antidepressant and cognitive outcomes61
Prefrontal-hippocampal interactions supporting the extinction of emotional memories: the retrieval stopping model61
TAAR1 agonist ulotaront modulates striatal and hippocampal glutamate function in a state-dependent manner60
Sex differences in offspring risk and resilience following 11β-hydroxylase antagonism in a rodent model of maternal immune activation60
A sex-specific role for the bed nucleus of the stria terminalis in proactive defensive behavior58
Leveraging ultra-high field (7T) MRI in psychiatric research58
Polygenic liability for antipsychotic dosage and polypharmacy - a real-world registry and biobank study58
Does cannabidiol make cannabis safer? A randomised, double-blind, cross-over trial of cannabis with four different CBD:THC ratios57
A biological phenotype of suicide attempt in adolescents with nonsuicidal self-injury: a machine-based learning approach56
Overdose mortality rates for opioids and stimulant drugs are substantially higher in men than in women: state-level analysis55
Is treatment-resistant schizophrenia a neuroimmune condition? Meta-analytic evidence from magnetic resonance spectroscopy54
Towards an understanding of psychedelic-induced neuroplasticity54
IN MEMORIAM John Gary Csernansky 1954–202253
A path to novel, effective treatments for schizophrenia51
Low doses of lysergic acid diethylamide (LSD) increase reward-related brain activity50
Effects of short-term quetiapine and lithium therapy for acute manic or mixed episodes on the limbic system and emotion regulation circuitry in youth with bipolar disorder48
NPP Editorial: tides of progress48
Correction to: Nucleus accumbens D1-receptors regulate and focus transitions to reward-seeking action47
In Memoriam: Larry J. Young, PhD46
In Memoriam: Dr. James B. Appel46
A covert cortical ensemble for learned fear suppression45
Disease-modifying pharmacological approaches to correcting basal forebrain cholinergic neuronal (BFCN) dysfunction and degeneration44
Psilocybin therapy for mood dysfunction in Parkinson’s disease: an open-label pilot trial43
Altered regulation of oligodendrocytes associated with parvalbumin neurons in the ventral hippocampus underlies fear generalization in male mice43
Deriving psychiatric symptom-based biomarkers from multivariate relationships between psychophysiological and biochemical measures42
Optogenetic inhibition of the dorsal hippocampus CA3 region during early-stage cocaine-memory reconsolidation disrupts subsequent context-induced cocaine seeking in rats42
Indirect, but not direct, lateral habenula projections to ventral tegmental area regulate the long-term consequences of neuropathic pain42
Pharmacogenomic testing for antidepressant treatment selection: lessons learned and roadmap forward41
Regulation of social hierarchy learning by serotonin transporter availability41
Chronic, combinatorial targeting of NMDARs and 5-HT4Rs exerts extended behavioral effects against stress-induced perseverative behavior and hyponeophagia41
The prefrontal cortex and OCD39
Transcriptomic profiling of reward and sensory brain areas in perinatal fentanyl exposed juvenile mice39
Reporting checklists in neuroimaging: promoting transparency, replicability, and reproducibility38
The efficacy and safety of zolpidem and zopiclone to treat insomnia in Alzheimer’s disease: a randomized, triple-blind, placebo-controlled trial37
In Memoriam—Robert M. A. Hirschfeld, MD, MSc36
Network homeostasis: functional brain network alterations and relapse in remitted late-life depression36
ACNP 60th Annual Meeting: Poster Abstracts P276 – P55036
For neuroscience, social history matters36
Impulsivity and risk-seeking as Bayesian inference under dopaminergic control36
Brain sex differences: the androgynous brain is advantageous for mental health and well-being34
Modulation of methamphetamine memory reconsolidation by neural projection from basolateral amygdala to nucleus accumbens34
Smoking-informed methylation and expression QTLs in human brain and colocalization with smoking-associated genetic loci34
Longitudinal associations between white matter integrity, early life adversities, and treatment response following cognitive-behavioral therapy in depression34
Multisystem stress response biotypes: a precision psychiatry approach to identifying and treating multidimensional risk factors for anhedonia in adolescence33
Persistent brain network signatures in psychosis: implications for diagnosis, prognosis, and treatment33
NPP’s approach toward improving rigor and transparency in clinical trials research33
Neuroimaging education in psychiatric training32
Dynamic and accessible pharmacogenomic results: a response to pharmacogenomic testing for antidepressant treatment selection32
Retraction Note: Association between neuromelanin-sensitive MRI signal and psychomotor slowing in late-life depression32
The biological embedding of structural inequities: new insight from neuroscience32
Correction to: Fluoxetine incentivizes ventral striatum encoding of reward and punishment31
Sex-specific and developmental effects of early life adversity on stress reactivity are rescued by postnatal knockdown of 5-HT1A autoreceptors31
Gamma-hydroxybutyrate to promote slow-wave sleep in major depressive disorder: a randomized crossover trial31
M1 acetylcholine receptors in somatostatin interneurons contribute to GABAergic and glutamatergic plasticity in the mPFC and antidepressant-like responses31
N-acetylcysteine does not alter neurometabolite levels in non-treatment seeking adolescents who use alcohol heavily: A preliminary randomized clinical trial31
Lithium rescues dendritic abnormalities in Ank3 deficiency models through the synergic effects of GSK3β and cyclic AMP signaling pathways30
Finding new and better treatments for psychiatric disorders29
Individualized functional connectome identified generalizable biomarkers for psychiatric symptoms in transdiagnostic patients29
Cigarette smoking is associated with reduced neuroinflammation and better cognitive control in people living with HIV29
One step at a time: use of single-session rTMS to test novel targets for substance use disorders29
Pharmacokinetic-pharmacodynamic analysis of drug liking blockade by buprenorphine subcutaneous depot (CAM2038) in participants with opioid use disorder28
Precision functional mapping for target engagement in drug development28
Perinatal exposure to fluoxetine and maternal adversity affect myelin-related gene expression and epigenetic regulation in the corticolimbic circuit of juvenile rats28
Cracking the chicken and egg problem of schizophrenia and substance use: Genetic interplay between schizophrenia, cannabis use disorder, and tobacco smoking27
Methylphenidate undermines or enhances divergent creativity depending on baseline dopamine synthesis capacity27
Activation of prefrontal parvalbumin interneurons ameliorates working memory deficit even under clinically comparable antipsychotic treatment in a mouse model of schizophrenia27
Connectome-based fingerprinting: reproducibility, precision, and behavioral prediction27
Endocannabinoids at the synapse and beyond: implications for neuropsychiatric disease pathophysiology and treatment27
Common and specific large-scale brain changes in major depressive disorder, anxiety disorders, and chronic pain: a transdiagnostic multimodal meta-analysis of structural and functional MRI studies27
Acute dose-dependent effects and self-guided titration of continuous N,N-dimethyltryptamine infusions in a double-blind placebo-controlled study in healthy participants27
In Memoriam George K. Aghajanian, M.D. 1932 -202327
Precision medicine in psychiatry: biomarkers to the forefront27
GluN2B inhibition confers resilience against long-term cocaine-induced neurocognitive sequelae27
A paraventricular thalamus to insular cortex glutamatergic projection gates “emotional” stress-induced binge eating in females27
The Tailtag: A multi-mouse tracking system to measure social dynamics in complex environments26
Identifying novel mechanisms and treatment targets for irritability and aggression in psychiatric disorders26
Cognition-enhancing and cognition-impairing doses of psychostimulants exert opposing actions on frontostriatal neural coding of delay in working memory26
Transdiagnostic subgroups of cognitive impairment in early affective and psychotic illness26
Disrupted brain state dynamics in opioid and alcohol use disorder: attenuation by nicotine use26
Stress integration by an ascending adrenergic-melanocortin circuit26
Mapping brain-wide activity networks: brainways as a tool for neurobiological discovery26
Central Executive Network drives delta-9-tetrahydrocannabinol (THC)-induced nonlinear changes in large-scale functional connectivity in adolescent nonhuman primates26
Reframing addiction: It’s not the destination, but the journey26
Cortical dopamine reduces the impact of motivational biases governing automated behaviour25
G protein-biased LPAR1 agonism of prototypic antidepressants: Implication in the identification of novel therapeutic target for depression25
Chronic MAP4343 reverses escalated alcohol drinking in a mouse model of alcohol use disorder25
Formation and fate of an engram in the lateral amygdala supporting a rewarding memory in mice25
N-acetylcysteine for youth cannabis use disorder: randomized controlled trial main findings25
Genomic modules and intramodular network concordance in susceptible and resilient male mice across models of stress24
Direct comparison of the acute effects of lysergic acid diethylamide and psilocybin in a double-blind placebo-controlled study in healthy subjects24
Estrous cycle stage gates the effect of stress on reward learning24
Cholinergic system adaptations are associated with cognitive function in people recently abstinent from smoking: a (-)-[18F]flubatine PET study24
Peripheral CB1 receptor blockade acts as a memory enhancer through a noradrenergic mechanism24
Oxytocin effects on amygdala reactivity to angry faces in males and females with antisocial personality disorder24
Genetic, environmental, and behavioral correlates of lifetime suicide attempt: Analysis of additive and interactive effects in two cohorts of US Army soldiers23
Critical review and recommendations for enhancement of the article on novel neurosteroid therapeutics for postpartum depression23
Neural basis of adolescent THC-induced potentiation of opioid responses later in life23
UNRAVELing the synergistic effects of psilocybin and environment on brain-wide immediate early gene expression in mice23
Validation of L-type calcium channel blocker amlodipine as a novel ADHD treatment through cross-species analysis, drug-target Mendelian randomization, and clinical evidence from medical records23
Longevity, enhanced memory, and altered density of dendritic spines in hippocampal CA3 and dentate gyrus after hemizygous deletion of Pde2a in mice23
ACNP 62nd Annual Meeting: Poster Abstracts P1 – P25022
Effects of lithium on aggression in Drosophila22
Correction: Punishment-resistant alcohol intake is mediated by the nucleus accumbens shell in female rats22
Opioid overdose and tolerance: is the recruitment of β-arrestin to the µ-receptor involved?22
Ensuring psychedelic treatments and research do not leave anyone behind22
Disassociating drug active ingredients from inactive: ketamine-like synaptic effects of a ketamine excipient22
The rostromedial tegmental nucleus gates fat overconsumption through ventral tegmental area output in male rats21
Greater subjective effects of a low dose of LSD in participants with depressed mood21
ACNP 63rd Annual Meeting: Poster Abstracts P305-P60821
Haven’t lost the positive feeling: a dose-response, oral alcohol challenge study in drinkers with alcohol use disorder21
Identifying brain-penetrant small-molecule modulators of human microglia using a cellular model of synaptic pruning20
Medial prefrontal cortex input to basolateral amygdala controls acute stress-induced short-term anxiety-like behavior in mice20
Toward understanding the opioid paradox: cellular mechanisms of opioid-induced hyperalgesia20
Using causal network mapping to clarify pre-clinical brain stimulation results20
The future of brain circuit-targeted therapeutics20
Cannabidiol mitigates alcohol dependence and withdrawal with neuroprotective effects in the basolateral amygdala and striatum19
Abnormal ventromedial-to-dorsolateral hierarchical topography of striatal circuits in cocaine use disorder and its modulations by brain stimulation19
GABA release from central amygdala neurotensin neurons differentially modulates ethanol consumption in male and female mice19
To dismantle structural racism in science, scientists need to learn how it works19
Correction to: Dose-related effects of ketamine for antidepressant-resistant symptoms of posttraumatic stress disorder in veterans and active duty military: a double-blind, randomized, placebo-control19
Correction: Neuroactive steroid biosynthesis during pregnancy predicts future postpartum depression: a role for the 3α and/or 3β-HSD neurosteroidogenic enzymes?19
Elevated dorsal medial prefrontal cortex to lateral habenula pathway activity mediates chronic stress-induced depressive and anxiety-like behaviors19
Correction: Neuropsychopharmacology Volume 50 Issue 119
Social isolation and aggression training lead to escalated aggression and hypothalamus-pituitary-gonad axis hyperfunction in mice19
The role of PFC networks in cognitive control and executive function18
Refining the study of decision-making in animals: differential effects of d-amphetamine and haloperidol in a novel touchscreen-automated Rearing-Effort Discounting (RED) task and the Fixed-Ratio Effor18
Ethical considerations in rapid and novel treatments in psychiatry18
Examining memory reconsolidation as a mechanism of nitrous oxide’s antidepressant action18
Real-time fMRI neurofeedback: the promising potential of brain-training technology to advance clinical neuroscience18
Acute sleep disruption reduces fear memories in male and female mice18
The anxiogenic drug yohimbine is a reinforcer in male and female rats18
Development of the McLean Hospital MENTOR Program to enhance mental health career pathways18
Prefrontal corticotropin-releasing factor promotes resilience to social stress18
ErbB4 in parvalbumin-positive interneurons mediates proactive interference in olfactory associative reversal learning18
Inhibition of dorsal raphe GABAergic neurons blocks hyperalgesia during heroin withdrawal18
Prefrontal cortex and depression18
IN MEMORIAM José Miguel Cañive, MD18
Atypical cortical networks in children at high-genetic risk of psychiatric and neurodevelopmental disorders18
Sex and sensitive period differences in potential effects of maltreatment on axial versus radial diffusivity in the corpus callosum18
Unexpected circuit-level tradeoffs in human stress resilience18
Demand for heroin in rats: effects of non-drug alternative substitutes and complements17
A review of diffusion MRI in mood disorders: mechanisms and predictors of treatment response17
Computational models of adaptive behavior and prefrontal cortex17
Opioid-blunted cortisol response to stress is associated with increased negative mood and wanting of social reward17
Control of dopamine communication by opioids: glutamate enters the discussion17
Large-scale structural network change correlates with clinical response to rTMS in depression17
Neural underpinnings of open-label placebo effects in emotional distress17
Pharmacological stimulation of infralimbic cortex after fear conditioning facilitates subsequent fear extinction16
Robust aversive effects of trace amine-associated receptor 1 activation in mice16
Functional genomics identify causal variant underlying the protective CTSH locus for Alzheimer’s disease16
Selective KOR antagonist alters functional patch sizes in individualized brain system: results from the Fast-fail Trial in Mood and Anxiety Spectrum Disorders (FAST-MAS)16
Peptidomimetic inhibitors targeting TrkB/PSD-95 signaling improves cognition and seizure outcomes in an Angelman Syndrome mouse model16
Cocaine restricts nucleus accumbens feedforward drive through a monoamine-independent mechanism16
Local and global effects of sedation in resting-state fMRI: a randomized, placebo-controlled comparison between etifoxine and alprazolam16
Nucleus of the solitary tract A2 neurons control feeding behaviors via projections to the paraventricular hypothalamus16
Advances in modeling learning and decision-making in neuroscience16
Sex-specific resting state brain network dynamics in patients with major depressive disorder16
The promise of precision functional mapping for neuroimaging in psychiatry16
IN MEMORIAM Ghanshyam Narayan Pandey 1937–202216
Publisher Correction to: Trace amine-associated receptor 1 agonism promotes wakefulness without impairment of cognition in Cynomolgus macaques16
Aversion-induced dopamine reductions predict drug-taking and escape behaviors16
Modulation of learning safety signals by acute stress: paraventricular thalamus and prefrontal inhibition16
Extended course accelerated intermittent theta burst stimulation as a substitute for depressed patients needing electroconvulsive therapy16
Identifying novel proteins for suicide attempt by integrating proteomes from brain and blood with genome-wide association data16
Comparative acute effects of mescaline, lysergic acid diethylamide, and psilocybin in a randomized, double-blind, placebo-controlled cross-over study in healthy participants16
Is the stereoisomer R-MDMA a safer version of MDMA?16
Retraction Note: Predator odor increases avoidance and glutamatergic synaptic transmission in the prelimbic cortex via corticotropin-releasing factor receptor 1 signaling16
Lateral habenula induces cognitive and affective dysfunctions in mice with neuropathic pain via an indirect pathway to the ventral tegmental area15
To indulge or enrich: how environmental enrichment affects neurons that promote food seeking15
Exploring the role of mu opioid receptors in the therapeutic potential and abuse liability of (S)-ketamine15
Targeting depression circuitry with H1 coil Transcranial Magnetic Stimulation: a retrospective circuit mapping study15
Common side effects of MDMA-assisted psychotherapy15
Unique and joint associations of polygenic risk for major depression and opioid use disorder with endogenous opioid system function15
ACNP 63rd Annual Meeting: Panels, Mini-Panels and Study Groups15
Electronic health records and stratified psychiatry: bridge to precision treatment?15
Dopamine D2 receptors in nucleus accumbens cholinergic interneurons increase impulsive choice15
PACAP regulates neuroendocrine and behavioral stress responses via CRF-containing neurons of the rat hypothalamic paraventricular nucleus15
Sex-related differences in violence exposure, neural reactivity to threat, and mental health15
Reply to Ploderl and Hengartner: learning about the course of suicidal behavior but not about the effects of SSRIs15
Isradipine augmentation of virtual reality cue exposure therapy for tobacco craving: a triple-blind randomized controlled trial15
Absence of TAAR1 function increases methamphetamine-induced excitability of dorsal raphe serotonin neurons and drives binge-level methamphetamine intake15
The effect of selective nigrostriatal dopamine excess on behaviors linked to the cognitive and negative symptoms of schizophrenia15
The neural and psychophysiological effects of cannabidiol in youth with alcohol use disorder: A randomized controlled clinical trial15
Residual deficits in functional brain activity after chronic cocaine self-administration in rhesus monkeys15
A projection from the medial prefrontal cortex to the lateral septum modulates coping behavior on the shock-probe test15
In memoriam – George R. Breese, Ph.D15
Correction: Lateral habenula induces cognitive and affective dysfunctions in mice with neuropathic pain via an indirect pathway to the ventral tegmental area15
Random forest and Shapley Additive exPlanations predict oxytocin targeted effects on brain functional networks involved in salience and sensorimotor processing, in a randomized clinical trial in autis14
Testosterone eliminates strategic prosocial behavior through impacting choice consistency in healthy males14
A meta-analysis of conditioned fear generalization in anxiety-related disorders14
ACNP 61st Annual Meeting: Poster Abstracts P271-P54014
In Memoriam Bernard Agranoff14
Mobile DNA and the brain14
Beyond the hypothalamus: roles for insulin as a regulator of neurotransmission, motivation, and feeding14
Serum amyloid P component (SAP) modulates antidepressant effects through promoting membrane insertion of the serotonin transporter14
Foraging with the frontal cortex: A cross-species evaluation of reward-guided behavior14
Pathways link environmental and genetic factors with structural brain networks and psychopathology in youth14
Retraction Note: Safety and efficacy of dapoxetine in the treatment of premature ejaculation: a double-blind, placebo-controlled, fixed-dose, randomized study14
The effects of D-Cycloserine on corticospinal excitability after repeated spaced intermittent theta-burst transcranial magnetic stimulation: A randomized controlled trial in healthy individuals14
Acute, chronic and conditioned effects of intranasal oxytocin in the mu-opioid receptor knockout mouse model of autism: Social context matters14
Timing matters: modeling the effects of gestational cannabis exposure on social behavior and microglia in the developing amygdala14
Selective 5HT3 antagonists and sensory processing: a systematic review14
Selective serotonin reuptake inhibitors and suicidal behaviour: a population-based cohort study14
In Memoriam: Burton M. Angrist, MD14
Neuroimaging in psychiatry: toward mechanistic insights and clinical utility13
(2-Aminopropyl)benzo[β]thiophenes (APBTs) are novel monoamine transporter ligands that lack stimulant effects but display psychedelic-like activity in mice13
Synaptic plasticity of the orbitofrontal cortex in obesity13
Effects of NMDA receptor antagonists on working memory and gamma oscillations, and the mediating role of the GluN2D subunit13
Integrating human brain proteomic data with genome-wide association study findings identifies novel brain proteins in substance use traits13
Identifying novel proteins underlying loneliness by integrating GWAS summary data with human brain proteomes13
Xanomeline restores endogenous nicotinic acetylcholine receptor signaling in mouse prefrontal cortex13
In memoriam: Kenneth E. Moore13
Detecting fine and elaborate movements with piezo sensors provides non-invasive access to overlooked behavioral components13
In memoriam: Dr. Thomas Lehner13
Disentangling the roles of dopamine and noradrenaline in the exploration-exploitation tradeoff during human decision-making13
Transcriptomics in the nucleus accumbens shell reveal sex- and reinforcer-specific signatures associated with morphine and sucrose craving13
ACNP 60th Annual Meeting: Poster Abstracts P551 – P83013
Acute effects of a high-fat diet on estrous cycling and body weight of intact female mice13
ACNP 63rd Annual Meeting: Keyword Index13
A dominant role for serotonin in the formation of human social hierarchies13
Kappa opioid receptors as modulators of novelty processing13
Targeting inhibitory control in youth irritability: challenges and opportunities13
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