Neuropsychopharmacology

Papers
(The TQCC of Neuropsychopharmacology is 13. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)
ArticleCitations
The role of prefrontal cortex in cognitive control and executive function334
Prefrontal cortex and depression185
The role of PFC networks in cognitive control and executive function159
Adverse effects of cannabidiol: a systematic review and meta-analysis of randomized clinical trials156
The ABCD study: understanding the development of risk for mental and physical health outcomes144
Frequency and profile of objective cognitive deficits in hospitalized patients recovering from COVID-19139
Augmentation therapy with minocycline in treatment-resistant depression patients with low-grade peripheral inflammation: results from a double-blind randomised clinical trial122
Opportunities and challenges in the collection and analysis of digital phenotyping data120
Acute dose-dependent effects of lysergic acid diethylamide in a double-blind placebo-controlled study in healthy subjects118
Me, myself, bye: regional alterations in glutamate and the experience of ego dissolution with psilocybin116
Dissecting diagnostic heterogeneity in depression by integrating neuroimaging and genetics109
Addiction as a brain disease revised: why it still matters, and the need for consilience102
Deep learning-based behavioral analysis reaches human accuracy and is capable of outperforming commercial solutions102
Prefrontal cortex, amygdala, and threat processing: implications for PTSD93
Development of prefrontal cortex92
All roads lead to the default-mode network—global source of DMN abnormalities in major depressive disorder90
Parvalbumin interneuron vulnerability and brain disorders90
Colon-delivered short-chain fatty acids attenuate the cortisol response to psychosocial stress in healthy men: a randomized, placebo-controlled trial87
Deep learning for small and big data in psychiatry84
Big behavior: challenges and opportunities in a new era of deep behavior profiling79
Mechanisms underlying dorsolateral prefrontal cortex contributions to cognitive dysfunction in schizophrenia79
Direct comparison of the acute effects of lysergic acid diethylamide and psilocybin in a double-blind placebo-controlled study in healthy subjects73
Advances in the computational understanding of mental illness72
Systems-based proteomics to resolve the biology of Alzheimer’s disease beyond amyloid and tau72
Evolution of prefrontal cortex71
Abnormalities in electroencephalographic microstates are state and trait markers of major depressive disorder71
Neurobiology of loneliness: a systematic review70
The prefrontal cortex, pathological anxiety, and anxiety disorders69
Sex differences in dopamine release regulation in the striatum67
Neuromodulation of prefrontal cortex cognitive function in primates: the powerful roles of monoamines and acetylcholine64
Shared genetic background between children and adults with attention deficit/hyperactivity disorder64
Choosing appropriate language to reduce the stigma around mental illness and substance use disorders60
Systematic misestimation of machine learning performance in neuroimaging studies of depression60
Digital health data-driven approaches to understand human behavior58
Evaluating the impact of trauma and PTSD on epigenetic prediction of lifespan and neural integrity58
Towards an understanding of psychedelic-induced neuroplasticity54
Exploratory study of the dose-related safety, tolerability, and efficacy of dimethyltryptamine (DMT) in healthy volunteers and major depressive disorder51
Pharmacokinetic, behavioral, and brain activity effects of Δ9-tetrahydrocannabinol in adolescent male and female rats50
The neurobiology of drug addiction: cross-species insights into the dysfunction and recovery of the prefrontal cortex49
Selective kappa-opioid antagonism ameliorates anhedonic behavior: evidence from the Fast-fail Trial in Mood and Anxiety Spectrum Disorders (FAST-MAS)48
The effects of inhibition of fatty acid amide hydrolase (FAAH) by JNJ-42165279 in social anxiety disorder: a double-blind, randomized, placebo-controlled proof-of-concept study48
A roadmap for development of neuro-oscillations as translational biomarkers for treatment development in neuropsychopharmacology48
Multiparametric mapping of white matter microstructure in catatonia46
The protective effect of operant social reward on cocaine self-administration, choice, and relapse is dependent on delay and effort for the social reward46
Ketamine metabolites, clinical response, and gamma power in a randomized, placebo-controlled, crossover trial for treatment-resistant major depression46
The addiction risk factor: A unitary genetic vulnerability characterizes substance use disorders and their associations with common correlates45
Downregulation of parvalbumin expression in the prefrontal cortex during adolescence causes enduring prefrontal disinhibition in adulthood45
Habit, choice, and addiction43
Lowered endogenous mu-opioid receptor availability in subclinical depression and anxiety43
Differentiating the effect of antipsychotic medication and illness on brain volume reductions in first-episode psychosis: A Longitudinal, Randomised, Triple-blind, Placebo-controlled MRI Study42
Cortical astrocytes regulate ethanol consumption and intoxication in mice41
Left prefrontal transcranial magnetic stimulation for treatment-resistant depression in adolescents: a double-blind, randomized, sham-controlled trial41
Covid-19 and promising solutions to combat symptoms of stress, anxiety and depression40
Pharmacological and genetic manipulations at the µ-opioid receptor reveal arrestin-3 engagement limits analgesic tolerance and does not exacerbate respiratory depression in mice40
Efficacy and tolerability of baclofen in a U.S. community population with alcohol use disorder: a dose-response, randomized, controlled trial39
Validation of a nicotine vapor self-administration model in rats with relevance to electronic cigarette use39
Reinforcement-learning in fronto-striatal circuits39
Prefrontal connectomics: from anatomy to human imaging39
Alterations in microbiome composition and metabolic byproducts drive behavioral and transcriptional responses to morphine39
Neuroimaging in schizophrenia: an overview of findings and their implications for synaptic changes39
Signature-based approaches for informed drug repurposing: targeting CNS disorders38
Cerebrospinal fluid endocannabinoid levels in Gilles de la Tourette syndrome38
Dose-related effects of ketamine for antidepressant-resistant symptoms of posttraumatic stress disorder in veterans and active duty military: a double-blind, randomized, placebo-controlled multi-cente38
Assessing the mechanisms of brain plasticity by transcranial magnetic stimulation37
Associations between different dimensions of prenatal distress, neonatal hippocampal connectivity, and infant memory37
Sex-specific neurobiological actions of prophylactic (R,S)-ketamine, (2R,6R)-hydroxynorketamine, and (2S,6S)-hydroxynorketamine37
Telemedicine for treating mental health and substance use disorders: reflections since the pandemic36
Repeated lysergic acid diethylamide (LSD) reverses stress-induced anxiety-like behavior, cortical synaptogenesis deficits and serotonergic neurotransmission decline36
The vagus nerve mediates the suppressing effects of peripherally administered oxytocin on methamphetamine self-administration and seeking in rats36
A versatile GPCR toolkit to track in vivo neuromodulation: not a one-size-fits-all sensor35
Psilocybin and LSD have no long-lasting effects in an animal model of alcohol relapse35
Metabolic activity in subcallosal cingulate predicts response to deep brain stimulation for depression35
Medial PFC AMPA receptor and BDNF signaling are required for the rapid and sustained antidepressant-like effects of 5-HT1A receptor stimulation34
Dose-response effects of d-amphetamine on effort-based decision-making and reinforcement learning34
Astrocyte-derived TNF and glutamate critically modulate microglia activation by methamphetamine34
Differential and unique patterns of synaptic miRNA expression in dorsolateral prefrontal cortex of depressed subjects34
Diazepam limits microglia-mediated neuronal remodeling in the prefrontal cortex and associated behavioral consequences following chronic unpredictable stress34
Oleoylethanolamide decreases frustration stress-induced binge-like eating in female rats: a novel potential treatment for binge eating disorder34
The clinical effectiveness of using a predictive algorithm to guide antidepressant treatment in primary care (PReDicT): an open-label, randomised controlled trial33
Real-time mobile monitoring of bipolar disorder: a review of evidence and future directions33
Meta-analysis of human prediction error for incentives, perception, cognition, and action33
Release of endogenous dynorphin opioids in the prefrontal cortex disrupts cognition33
A potential biomarker for treatment stratification in psychosis: evaluation of an [18F] FDOPA PET imaging approach33
Accelerated brain aging predicts impulsivity and symptom severity in depression33
Adolescent alcohol exposure produces sex differences in negative affect-like behavior and group I mGluR BNST plasticity33
Interactive relations between maternal prenatal stress, fetal brain connectivity, and gestational age at delivery33
Prefrontal-hippocampal interactions supporting the extinction of emotional memories: the retrieval stopping model33
Sex, stress, and prefrontal cortex: influence of biological sex on stress-promoted cocaine seeking32
Pharmacokinetics trumps pharmacodynamics during cocaine choice: a reconciliation with the dopamine hypothesis of addiction32
Progressive brain structural alterations assessed via causal analysis in patients with generalized anxiety disorder31
Association of locus coeruleus integrity with Braak stage and neuropsychiatric symptom severity in Alzheimer’s disease31
Functional connectivity during frustration: a preliminary study of predictive modeling of irritability in youth31
Computational models of adaptive behavior and prefrontal cortex31
The effects of eszopiclone on sleep spindles and memory consolidation in schizophrenia: a randomized clinical trial31
Leveraging large genomic datasets to illuminate the pathobiology of autism spectrum disorders31
Integration of brain and behavior measures for identification of data-driven groups cutting across children with ASD, ADHD, or OCD31
Prognostic neuroimaging biomarkers of trauma-related psychopathology: resting-state fMRI shortly after trauma predicts future PTSD and depression symptoms in the AURORA study31
Compulsive alcohol consumption is regulated by dorsal striatum fast-spiking interneurons31
Common and specific large-scale brain changes in major depressive disorder, anxiety disorders, and chronic pain: a transdiagnostic multimodal meta-analysis of structural and functional MRI studies30
The role of dopamine in dynamic effort-reward integration30
Synaptic plasticity and mental health: methods, challenges and opportunities30
Proof of mechanism and target engagement of glutamatergic drugs for the treatment of schizophrenia: RCTs of pomaglumetad and TS-134 on ketamine-induced psychotic symptoms and pharmacoBOLD in healthy v30
The role of anterior insula–brainstem projections and alpha-1 noradrenergic receptors for compulsion-like and alcohol-only drinking29
Modulating microglia activation prevents maternal immune activation induced schizophrenia-relevant behavior phenotypes via arginase 1 in the dentate gyrus29
What’s wrong with my experiment?: The impact of hidden variables on neuropsychopharmacology research29
Rapid-acting antidepressants and the circadian clock29
The renin–angiotensin system in PTSD: a replication and extension29
Transcriptome-wide association study of treatment-resistant depression and depression subtypes for drug repurposing28
The prefrontal cortex and OCD28
Advances in modeling learning and decision-making in neuroscience28
Sleep dysregulation in binge eating disorder and “food addiction”: the orexin (hypocretin) system as a potential neurobiological link28
Prefrontal cortex interactions with the amygdala in primates28
Intrinsic connectivity of the prefrontal cortex and striato-limbic system respectively differentiate major depressive from generalized anxiety disorder28
The association between lithium use and neurocognitive performance in patients with bipolar disorder28
The effects of FAAH inhibition on the neural basis of anxiety-related processing in healthy male subjects: a randomized clinical trial28
Cannabinoid CB2 receptors mediate the anxiolytic-like effects of monoacylglycerol lipase inhibition in a rat model of predator-induced fear27
Opioid-sparing effect of cannabinoids for analgesia: an updated systematic review and meta-analysis of preclinical and clinical studies27
Neurobiological consequences of racial disparities and environmental risks: a critical gap in understanding psychiatric disorders27
The prediction-error hypothesis of schizophrenia: new data point to circuit-specific changes in dopamine activity27
Somatostatin neurons control an alcohol binge drinking prelimbic microcircuit in mice27
Transgenerational modification of dopaminergic dysfunctions induced by maternal immune activation27
A distributed frontotemporal network underlies gamma-band synchronization impairments in schizophrenia patients27
Associations among locus coeruleus catecholamines, tau pathology, and memory in aging26
Perinatal THC exposure via lactation induces lasting alterations to social behavior and prefrontal cortex function in rats at adulthood26
Association of gray matter volumes with general and specific dimensions of psychopathology in children26
Projection-specific deficits in synaptic transmission in adult Sapap3-knockout mice26
Foraging with the frontal cortex: A cross-species evaluation of reward-guided behavior26
Autism risk gene KMT5B deficiency in prefrontal cortex induces synaptic dysfunction and social deficits via alterations of DNA repair and gene transcription25
Interactions between hippocampal activity and striatal dopamine in people at clinical high risk for psychosis: relationship to adverse outcomes25
Biotyping in psychosis: using multiple computational approaches with one data set25
Association between irritability and suicidal ideation in three clinical trials of adults with major depressive disorder25
Remifentanil self-administration in mice promotes sex-specific prefrontal cortex dysfunction underlying deficits in cognitive flexibility25
Astrocyte regulation of synaptic signaling in psychiatric disorders25
Corticosterone after acute stress prevents the delayed effects on the amygdala24
Dynamics of amygdala connectivity in bipolar disorders: a longitudinal study across mood states24
Structural–functional decoupling predicts suicide attempts in bipolar disorder patients with a current major depressive episode24
Convergent genomic and pharmacological evidence of PI3K/GSK3 signaling alterations in neurons from schizophrenia patients24
Interactions between ventrolateral prefrontal and anterior cingulate cortex during learning and behavioural change24
Brain structural correlates of familial risk for mental illness: a meta-analysis of voxel-based morphometry studies in relatives of patients with psychotic or mood disorders24
Clinical, behavioral, and neural measures of reward processing correlate with escitalopram response in depression: a Canadian Biomarker Integration Network in Depression (CAN-BIND-1) Report24
Dopamine transporter function fluctuates across sleep/wake state: potential impact for addiction24
Co-released norepinephrine and galanin act on different timescales to promote stress-induced anxiety-like behavior24
Identification of transdiagnostic psychiatric disorder subtypes using unsupervised learning24
Neural circuits regulating prosocial behaviors24
Does cannabidiol make cannabis safer? A randomised, double-blind, cross-over trial of cannabis with four different CBD:THC ratios24
Complement component C4 levels in the cerebrospinal fluid and plasma of patients with schizophrenia23
Long-term safety and maintenance of response with esketamine nasal spray in participants with treatment-resistant depression: interim results of the SUSTAIN-3 study23
Regulation of dopamine-dependent transcription and cocaine action by Gadd45b23
Dysregulation of threat neurocircuitry during fear extinction: the role of anhedonia23
Decreased striatal adenosine A2A-dopamine D2 receptor heteromerization in schizophrenia23
Applied natural language processing in mental health big data23
Efficacy and safety of transcranial direct current stimulation as an add-on treatment for obsessive-compulsive disorder: a randomized, sham-controlled trial23
Regulation of risky decision making by gonadal hormones in males and females23
Telomere length and human hippocampal neurogenesis23
Beta-adrenergic blockade blunts inflammatory and antiviral/antibody gene expression responses to acute psychosocial stress23
Telomere attrition and inflammatory load in severe psychiatric disorders and in response to psychotropic medications22
Nesfatin-1 decreases the motivational and rewarding value of food22
Chronic social defeat stress impairs goal-directed behavior through dysregulation of ventral hippocampal activity in male mice22
Sex and strain differences in dynamic and static properties of the mesolimbic dopamine system22
Elevated fatty acid amide hydrolase in the prefrontal cortex of borderline personality disorder: a [11C]CURB positron emission tomography study22
A robust and reproducible connectome fingerprint of ketamine is highly associated with the connectomic signature of antidepressants22
Selective serotonin reuptake inhibitors and suicidal behaviour: a population-based cohort study22
The role of dopamine dysregulation and evidence for the transdiagnostic nature of elevated dopamine synthesis in psychosis: a positron emission tomography (PET) study comparing schizophrenia, delusion22
Oxytocin receptor expression patterns in the human brain across development22
A meta-analysis of conditioned fear generalization in anxiety-related disorders22
Interpretation of psychiatric genome-wide association studies with multispecies heterogeneous functional genomic data integration21
Pituitary adenylate cyclase-activating polypeptide (PACAP) modulates dependence-induced alcohol drinking and anxiety-like behavior in male rats21
Anterior cingulate cortex is necessary for spontaneous opioid withdrawal and withdrawal-induced hyperalgesia in male mice21
Deep transcriptome sequencing of subgenual anterior cingulate cortex reveals cross-diagnostic and diagnosis-specific RNA expression changes in major psychiatric disorders21
Optogenetic stimulation of lateral hypothalamic orexin/dynorphin inputs in the ventral tegmental area potentiates mesolimbic dopamine neurotransmission and promotes reward-seeking behaviours21
Methylphenidate boosts choices of mental labor over leisure depending on striatal dopamine synthesis capacity21
Systemic enhancement of serotonin signaling reverses social deficits in multiple mouse models for ASD21
White-matter free-water diffusion MRI in schizophrenia: a systematic review and meta-analysis21
Sustained effects of single doses of classical psychedelics in humans21
Functional connectivity underpinnings of electroconvulsive therapy-induced memory impairments in patients with depression21
The anterior retrosplenial cortex encodes event-related information and the posterior retrosplenial cortex encodes context-related information during memory formation20
Memantine effects on auditory discrimination and training in schizophrenia patients20
Astrocyte-neuron signaling in the mesolimbic dopamine system: the hidden stars of dopamine signaling20
Incerto-thalamic modulation of fear via GABA and dopamine20
Long-term alcohol consumption alters dorsal striatal dopamine release and regulation by D2 dopamine receptors in rhesus macaques20
Endogenous theta stimulation during meditation predicts reduced opioid dosing following treatment with Mindfulness-Oriented Recovery Enhancement20
Dopamine D2 receptor signaling on iMSNs is required for initiation and vigor of learned actions20
Hippocampus and amygdala fear memory engrams re-emerge after contextual fear relapse20
Patient-specific connectomic models correlate with, but do not reliably predict, outcomes in deep brain stimulation for obsessive-compulsive disorder20
Big data in psychiatry: multiomics, neuroimaging, computational modeling, and digital phenotyping20
Sex specific effects of “junk-food” diet on calcium permeable AMPA receptors and silent synapses in the nucleus accumbens core20
Measuring maladaptive avoidance: from animal models to clinical anxiety20
MDMA-induced changes in within-network connectivity contradict the specificity of these alterations for the effects of serotonergic hallucinogens20
A cross-species assay demonstrates that reward responsiveness is enduringly impacted by adverse, unpredictable early-life experiences20
Positive modulation of NMDA receptors by AGN-241751 exerts rapid antidepressant-like effects via excitatory neurons20
The M1/M4 preferring muscarinic agonist xanomeline modulates functional connectivity and NMDAR antagonist-induced changes in the mouse brain20
Concordant neurophysiological signatures of cognitive control in humans and rats20
Prefrontal contributions to the stability and variability of thought and conscious experience19
Theta–gamma coupling and ordering information: a stable brain–behavior relationship across cognitive tasks and clinical conditions19
Beta-caryophyllene inhibits cocaine  addiction-related behavior by activation of PPARα and PPARγ: repurposing a FDA-approved food additive for cocaine use disorder19
Neuroimaging correlates and predictors of response to repeated-dose intravenous ketamine in PTSD: preliminary evidence19
Changes in the brain structural connectome after a prospective randomized clinical trial of lithium and quetiapine treatment in youth with bipolar disorder19
Insular cortex corticotropin-releasing factor integrates stress signaling with social affective behavior19
Genome-wide DNA methylation differences in nucleus accumbens of smokers vs. nonsmokers19
Transcriptional signatures of the cortical morphometric similarity network gradient in first-episode, treatment-naive major depressive disorder19
Distinct trajectories of response to prefrontal tDCS in major depression: results from a 3-arm randomized controlled trial19
Systematic manipulations of the biological stress systems result in sex-specific compensatory stress responses and negative mood outcomes19
Aberrant triple-network connectivity patterns discriminate biotypes of first-episode medication-naive schizophrenia in two large independent cohorts19
Investigation of glycaemic traits in psychiatric disorders using Mendelian randomisation revealed a causal relationship with anorexia nervosa19
Using prefrontal transcranial direct current stimulation (tDCS) to enhance proactive cognitive control in schizophrenia19
Enhanced heroin self-administration and distinct dopamine adaptations in female rats19
Optogenetic inhibition of indirect pathway neurons in the dorsomedial striatum reduces excessive grooming in Sapap3-knockout mice19
Adolescent stress sensitizes the adult neuroimmune transcriptome and leads to sex-specific microglial and behavioral phenotypes19
Restoring glutamate homeostasis in the nucleus accumbens via endocannabinoid-mimetic drug prevents relapse to cocaine seeking behavior in rats18
Independent replications and integrative analyses confirm TRANK1 as a susceptibility gene for bipolar disorder18
Cocaine and amphetamine regulated transcript (CART) signalling in the central nucleus of the amygdala modulates stress-induced alcohol seeking18
Toward dynamic phenotypes and the scalable measurement of human behavior18
Traumatic memory reactivation with or without propranolol for PTSD and comorbid MD symptoms: a randomised clinical trial18
Comorbid anxiety-like behavior in a rat model of colitis is mediated by an upregulation of corticolimbic fatty acid amide hydrolase18
GSK3β inhibition restores cortical gamma oscillation and cognitive behavior in a mouse model of NMDA receptor hypofunction relevant to schizophrenia18
Salivary beta-endorphin in nonsuicidal self-injury: an ambulatory assessment study18
Behavioral and neurobiological effects of GnRH agonist treatment in mice—potential implications for puberty suppression in transgender individuals18
Genetic underpinnings of sociability in the general population18
Change in prefrontal activity and executive functions after action-based cognitive remediation in bipolar disorder: a randomized controlled trial18
Δ9-Tetrahydrocannabinol (THC) impairs visual working memory performance: a randomized crossover trial18
Intrinsic reward circuit connectivity profiles underlying symptom and quality of life outcomes following antidepressant medication: a report from the iSPOT-D trial17
Histone H3 dopaminylation in ventral tegmental area underlies heroin-induced transcriptional and behavioral plasticity in male rats17
Sex differences in appetitive and reactive aggression17
Glutamine-to-glutamate ratio in the nucleus accumbens predicts effort-based motivated performance in humans17
Learning from lorcaserin: lessons from the negative clinical trial of lorcaserin to treat cocaine use disorder17
Genetic contributions to alcohol use disorder treatment outcomes: a genome-wide pharmacogenomics study17
Behavioral and accumbens synaptic plasticity induced by cues associated with restraint stress17
The efficacy and safety of zolpidem and zopiclone to treat insomnia in Alzheimer’s disease: a randomized, triple-blind, placebo-controlled trial17
Orexin-1 receptor signaling in ventral tegmental area mediates cue-driven demand for cocaine17
Brain reactivity during aggressive response in women with premenstrual dysphoric disorder treated with a selective progesterone receptor modulator17
Predicting change in diagnosis from major depression to bipolar disorder after antidepressant initiation17
Unravelling the effects of methylphenidate on the dopaminergic and noradrenergic functional circuits17
Within-subject, double-blinded, randomized, and placebo-controlled evaluation of the combined effects of the cannabinoid dronabinol and the opioid hydromorphone in a human laboratory pain model16
Mesocortical BDNF signaling mediates antidepressive-like effects of lithium16
Lower cholinergic basal forebrain volumes link with cognitive difficulties in schizophrenia16
Are we compulsively chasing rainbows?16
Maternal dietary omega-3 deficiency worsens the deleterious effects of prenatal inflammation on the gut-brain axis in the offspring across lifetime16
Synaptic control of DNA methylation involves activity-dependent degradation of DNMT3A1 in the nucleus16
Increased functional coupling of the mu opioid receptor in the anterior insula of depressed individuals16
Psilocybin for treatment resistant depression in patients taking a concomitant SSRI medication16
Long-term effects of intermittent early life stress on primate prefrontal–subcortical functional connectivity16
Metabolic adverse effects of off-label use of second-generation antipsychotics in the adult population: a systematic review and meta-analysis16
Randomized controlled experimental study of hydrocortisone and D-cycloserine effects on fear extinction in PTSD16
Reduced GABA/glutamate in the thalamus of individuals at clinical high risk for psychosis16
Systematic review of structural and functional neuroimaging studies of cannabis use in adolescence and emerging adulthood: evidence from 90 studies and 9441 participants16
Replicable association between human cytomegalovirus infection and reduced white matter fractional anisotropy in major depressive disorder16
A novel multidimensional reinforcement task in mice elucidates sex-specific behavioral strategies16
Intergenerational trauma is associated with expression alterations in glucocorticoid- and immune-related genes16
Dynamic activity of interpeduncular nucleus GABAergic neurons controls expression of nicotine withdrawal in male mice16
Genome-wide association study accounting for anticholinergic burden to examine cognitive dysfunction in psychotic disorders16
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