Neuropsychopharmacology

Papers
(The TQCC of Neuropsychopharmacology is 11. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)
ArticleCitations
A new prism next to motherhood’s light: uncovering changes in neural function following childbirth204
Using metabolic imaging to investigate neuromodulatory mechanisms of rTMS195
Correction to: Isoform-selective phosphoinositide 3-kinase inhibition ameliorates a broad range of fragile X syndrome-associated deficits in a mouse model172
ACNP 62nd Annual Meeting: Keyword Index146
The National Institute on Drug Abuse Summer Research Internship Program: Building a Diverse National Scientific Workforce144
A biological phenotype of suicide attempt in adolescents with nonsuicidal self-injury: a machine-based learning approach109
Potentiation of AMPA receptors for rapid therapeutic gain in psychiatry has reached a new level of excitement108
Distinct roles of excitatory and inhibitory neurons in the medial prefrontal cortex in the expression and reconsolidation of methamphetamine-associated memory in male mice103
Role of neuropeptide neuromedin U in the nucleus accumbens shell in cocaine self-administration in male rats97
A double-blind, randomized controlled study of the effects of celecoxib on clinical symptoms and cognitive impairment in patients with drug-naïve first episode schizophrenia: pharmacogenetic impact of96
Validation of a non-food or water motivated effort-based foraging task as a measure of motivational state in male mice93
Delayed estrogen actions diminish food consumption without changing food approach, motor activity, or hypothalamic activation elicited by corticostriatal µ-opioid signaling93
It’s about racism, not race: a call to purge oppressive practices from neuropsychiatry and scientific discovery88
Motor signs in late life depression relate to altered subcortical synaptic density and gray matter volume: an 11C-UCB-J PET-MR study86
Leveraging large-scale brain networks in rats to understand neurological and psychiatric disorders in humans76
Is treatment-resistant schizophrenia a neuroimmune condition? Meta-analytic evidence from magnetic resonance spectroscopy74
Altered neuronal activity in the ventromedial prefrontal cortex drives nicotine intake escalation74
Fetal behavior and gestational serotonin reuptake inhibitor exposure: relationships between behavior, drug dosage, plasma drug level, and a measure of drug bioeffect73
ACNP 61st Annual Meeting: Poster Abstracts P541 – P80973
Pramipexole modulates fronto-subthalamic pathway in sequential working memory68
Does cannabidiol make cannabis safer? A randomised, double-blind, cross-over trial of cannabis with four different CBD:THC ratios67
A sex-specific role for the bed nucleus of the stria terminalis in proactive defensive behavior67
Polygenic liability for antipsychotic dosage and polypharmacy - a real-world registry and biobank study67
Infant sensory gating and a developmental cascade to autistic traits and anxiety64
Fueling the future: brain bioenergetics as a driver of neurodevelopment and mental health trajectories61
Parvalbumin interneuron mGlu5 receptors govern sex differences in prefrontal cortex physiology and binge drinking60
TAAR1 agonist ulotaront modulates striatal and hippocampal glutamate function in a state-dependent manner56
The GABAA receptor modulator zolpidem augments hippocampal-prefrontal coupling during non-REM sleep54
Sex differences in offspring risk and resilience following 11β-hydroxylase antagonism in a rodent model of maternal immune activation54
Inhibition of striatal indirect pathway during second postnatal week leads to long-lasting deficits in motivated behavior51
Targeted and transient opening of the blood brain barrier in discrete neurocircuits and brain regions51
Amplitude-determined seizure-threshold, electric field modeling, and electroconvulsive therapy antidepressant and cognitive outcomes50
Hippocampus and amygdala fear memory engrams re-emerge after contextual fear relapse50
Prefrontal allopregnanolone mediates the adverse effects of acute stress in a mouse model of tic pathophysiology49
Data-driven connectivity profiles relate to smoking cessation outcomes49
Epigenetic regulation of brain development, plasticity, and response to early-life stress48
Gestational ethanol exposure impairs motor skills in female mice through dysregulated striatal dopamine and acetylcholine function46
Leveraging ultra-high field (7T) MRI in psychiatric research44
Overdose mortality rates for opioids and stimulant drugs are substantially higher in men than in women: state-level analysis44
IN MEMORIAM John Gary Csernansky 1954–202242
Towards an understanding of psychedelic-induced neuroplasticity42
NPP Editorial: tides of progress41
Indirect, but not direct, lateral habenula projections to ventral tegmental area regulate the long-term consequences of neuropathic pain41
In Memoriam: Larry J. Young, PhD40
Correction to: Nucleus accumbens D1-receptors regulate and focus transitions to reward-seeking action39
Deriving psychiatric symptom-based biomarkers from multivariate relationships between psychophysiological and biochemical measures38
In Memoriam: Dr. James B. Appel38
A covert cortical ensemble for learned fear suppression38
Chronic, combinatorial targeting of NMDARs and 5-HT4Rs exerts extended behavioral effects against stress-induced perseverative behavior and hyponeophagia38
Namesake of PF-05231023: how nomenclature confusion leads to experimental misinterpretation in pharmacologic research36
Regulation of social hierarchy learning by serotonin transporter availability36
Chronic treatment with fluoxetine regulates mitochondrial features and plasticity-associated transcriptomic pathways in parvalbumin-positive interneurons of prefrontal cortex36
Hyper-maturity and accelerated aging in the hippocampus of mouse models of neuropsychiatric disorders with anxiety-like behavior36
Menstrual cycle and mental health in adolescents: a developmental neuroendocrine perspective36
Pharmacogenomic testing for antidepressant treatment selection: lessons learned and roadmap forward35
Reporting checklists in neuroimaging: promoting transparency, replicability, and reproducibility35
Effects of short-term quetiapine and lithium therapy for acute manic or mixed episodes on the limbic system and emotion regulation circuitry in youth with bipolar disorder35
Digital frontlines: leveraging AI to augment human expertise in crisis and combat situations35
Optogenetic inhibition of the dorsal hippocampus CA3 region during early-stage cocaine-memory reconsolidation disrupts subsequent context-induced cocaine seeking in rats35
Network homeostasis: functional brain network alterations and relapse in remitted late-life depression35
Altered regulation of oligodendrocytes associated with parvalbumin neurons in the ventral hippocampus underlies fear generalization in male mice34
The hippocampus as a central hub in ketamine’s antidepressant action: from molecules to circuit rewiring34
A path to novel, effective treatments for schizophrenia34
Psilocybin therapy for mood dysfunction in Parkinson’s disease: an open-label pilot trial34
Low doses of lysergic acid diethylamide (LSD) increase reward-related brain activity33
Transcriptomic profiling of reward and sensory brain areas in perinatal fentanyl exposed juvenile mice33
ACNP 60th Annual Meeting: Poster Abstracts P276 – P55032
In Memoriam—Robert M. A. Hirschfeld, MD, MSc32
Persistent brain network signatures in psychosis: implications for diagnosis, prognosis, and treatment32
NPP’s approach toward improving rigor and transparency in clinical trials research31
Correction to: Fluoxetine incentivizes ventral striatum encoding of reward and punishment31
GluN2B inhibition confers resilience against long-term cocaine-induced neurocognitive sequelae31
Evenamide reverses schizophrenia-related dysfunction in a neurodevelopmental animal model31
The biological embedding of structural inequities: new insight from neuroscience30
Dynamic and accessible pharmacogenomic results: a response to pharmacogenomic testing for antidepressant treatment selection29
Neuroimaging education in psychiatric training29
One step at a time: use of single-session rTMS to test novel targets for substance use disorders29
Retraction Note: Association between neuromelanin-sensitive MRI signal and psychomotor slowing in late-life depression29
Precision functional mapping for target engagement in drug development29
A paraventricular thalamus to insular cortex glutamatergic projection gates “emotional” stress-induced binge eating in females28
Individualized functional connectome identified generalizable biomarkers for psychiatric symptoms in transdiagnostic patients28
Longitudinal associations between white matter integrity, early life adversities, and treatment response following cognitive-behavioral therapy in depression28
Sex-specific and developmental effects of early life adversity on stress reactivity are rescued by postnatal knockdown of 5-HT1A autoreceptors27
Endocannabinoids at the synapse and beyond: implications for neuropsychiatric disease pathophysiology and treatment27
Cigarette smoking is associated with reduced neuroinflammation and better cognitive control in people living with HIV27
Multisystem stress response biotypes: a precision psychiatry approach to identifying and treating multidimensional risk factors for anhedonia in adolescence27
Finding new and better treatments for psychiatric disorders27
Connectome-based fingerprinting: reproducibility, precision, and behavioral prediction26
nNOS-expressing neurons in the mPFC mediate depression-related behaviors in mice through pPVT-mPFC projections26
Acute dose-dependent effects and self-guided titration of continuous N,N-dimethyltryptamine infusions in a double-blind placebo-controlled study in healthy participants26
Gamma-hydroxybutyrate to promote slow-wave sleep in major depressive disorder: a randomized crossover trial26
Smoking-informed methylation and expression QTLs in human brain and colocalization with smoking-associated genetic loci26
Common and specific large-scale brain changes in major depressive disorder, anxiety disorders, and chronic pain: a transdiagnostic multimodal meta-analysis of structural and functional MRI studies26
Modulation of methamphetamine memory reconsolidation by neural projection from basolateral amygdala to nucleus accumbens26
M1 acetylcholine receptors in somatostatin interneurons contribute to GABAergic and glutamatergic plasticity in the mPFC and antidepressant-like responses25
Activation of prefrontal parvalbumin interneurons ameliorates working memory deficit even under clinically comparable antipsychotic treatment in a mouse model of schizophrenia25
For neuroscience, social history matters25
Lithium rescues dendritic abnormalities in Ank3 deficiency models through the synergic effects of GSK3β and cyclic AMP signaling pathways24
Perinatal exposure to fluoxetine and maternal adversity affect myelin-related gene expression and epigenetic regulation in the corticolimbic circuit of juvenile rats24
Pharmacokinetic-pharmacodynamic analysis of drug liking blockade by buprenorphine subcutaneous depot (CAM2038) in participants with opioid use disorder24
N-acetylcysteine does not alter neurometabolite levels in non-treatment seeking adolescents who use alcohol heavily: A preliminary randomized clinical trial23
Stress integration by an ascending adrenergic-melanocortin circuit23
Methylphenidate undermines or enhances divergent creativity depending on baseline dopamine synthesis capacity23
The Tailtag: A multi-mouse tracking system to measure social dynamics in complex environments23
In Memoriam George K. Aghajanian, M.D. 1932 -202323
Mapping brain-wide activity networks: brainways as a tool for neurobiological discovery22
Cracking the chicken and egg problem of schizophrenia and substance use: Genetic interplay between schizophrenia, cannabis use disorder, and tobacco smoking22
Central Executive Network drives delta-9-tetrahydrocannabinol (THC)-induced nonlinear changes in large-scale functional connectivity in adolescent nonhuman primates22
Reframing addiction: It’s not the destination, but the journey22
Chronic MAP4343 reverses escalated alcohol drinking in a mouse model of alcohol use disorder22
G protein-biased LPAR1 agonism of prototypic antidepressants: Implication in the identification of novel therapeutic target for depression22
Cognition-enhancing and cognition-impairing doses of psychostimulants exert opposing actions on frontostriatal neural coding of delay in working memory22
Estrous cycle stage gates the effect of stress on reward learning21
From symptom-based heterogeneity to mechanism-based profiling in youth ADHD: the promise of computational psychiatry21
Formation and fate of an engram in the lateral amygdala supporting a rewarding memory in mice21
Cholinergic system adaptations are associated with cognitive function in people recently abstinent from smoking: a (-)-[18F]flubatine PET study21
Neural basis of adolescent THC-induced potentiation of opioid responses later in life21
Cortical dopamine reduces the impact of motivational biases governing automated behaviour21
Identifying behavioral and biological predictors of cannabis vapor self-administration in rats21
Peripheral CB1 receptor blockade acts as a memory enhancer through a noradrenergic mechanism21
Transdiagnostic subgroups of cognitive impairment in early affective and psychotic illness20
N-acetylcysteine for youth cannabis use disorder: randomized controlled trial main findings20
Direct comparison of the acute effects of lysergic acid diethylamide and psilocybin in a double-blind placebo-controlled study in healthy subjects20
Critical review and recommendations for enhancement of the article on novel neurosteroid therapeutics for postpartum depression20
Psychedelics produce enduring behavioral effects and functional plasticity through mechanisms independent of structural plasticity20
UNRAVELing the synergistic effects of psilocybin and environment on brain-wide immediate early gene expression in mice20
Oxytocin effects on amygdala reactivity to angry faces in males and females with antisocial personality disorder20
Disrupted brain state dynamics in opioid and alcohol use disorder: attenuation by nicotine use20
Genetic, environmental, and behavioral correlates of lifetime suicide attempt: Analysis of additive and interactive effects in two cohorts of US Army soldiers20
Investigating hierarchical critical periods in human neurodevelopment20
Validation of L-type calcium channel blocker amlodipine as a novel ADHD treatment through cross-species analysis, drug-target Mendelian randomization, and clinical evidence from medical records20
Examining memory reconsolidation as a mechanism of nitrous oxide’s antidepressant action19
ACNP 63rd Annual Meeting: Poster Abstracts P305-P60819
Ensuring psychedelic treatments and research do not leave anyone behind19
Effects of lithium on aggression in Drosophila19
Rewired realities: novel insights into the neurobiology of cannabis use disorder and psychosis19
Correction: Punishment-resistant alcohol intake is mediated by the nucleus accumbens shell in female rats19
The rostromedial tegmental nucleus gates fat overconsumption through ventral tegmental area output in male rats19
Ethical considerations in rapid and novel treatments in psychiatry19
Independent brain cortical signatures of risk for adolescent cannabis use and consequences of such use are moderated by sex19
Real-time fMRI neurofeedback: the promising potential of brain-training technology to advance clinical neuroscience19
Disassociating drug active ingredients from inactive: ketamine-like synaptic effects of a ketamine excipient19
Longevity, enhanced memory, and altered density of dendritic spines in hippocampal CA3 and dentate gyrus after hemizygous deletion of Pde2a in mice19
Considerations for conducting developmental neuroimaging research on mental health topics19
Quiet waves, deep impact: acoustic modeling of low-intensity focused ultrasound19
Medial prefrontal cortex input to basolateral amygdala controls acute stress-induced short-term anxiety-like behavior in mice19
Correction: Neuropsychopharmacology Volume 50 Issue 118
To dismantle structural racism in science, scientists need to learn how it works18
Prefrontal corticotropin-releasing factor promotes resilience to social stress18
Correction: Neuroactive steroid biosynthesis during pregnancy predicts future postpartum depression: a role for the 3α and/or 3β-HSD neurosteroidogenic enzymes?18
Atypical cortical networks in children at high-genetic risk of psychiatric and neurodevelopmental disorders18
Inhibition of dorsal raphe GABAergic neurons blocks hyperalgesia during heroin withdrawal18
Correction to: Dose-related effects of ketamine for antidepressant-resistant symptoms of posttraumatic stress disorder in veterans and active duty military: a double-blind, randomized, placebo-control18
Abnormal ventromedial-to-dorsolateral hierarchical topography of striatal circuits in cocaine use disorder and its modulations by brain stimulation18
Development of the McLean Hospital MENTOR Program to enhance mental health career pathways18
Using causal network mapping to clarify pre-clinical brain stimulation results18
Acute sleep disruption reduces fear memories in male and female mice17
The future of brain circuit-targeted therapeutics17
Greater subjective effects of a low dose of LSD in participants with depressed mood17
Haven’t lost the positive feeling: a dose-response, oral alcohol challenge study in drinkers with alcohol use disorder17
GABA release from central amygdala neurotensin neurons differentially modulates ethanol consumption in male and female mice17
ACNP 62nd Annual Meeting: Poster Abstracts P1 – P25017
Elevated dorsal medial prefrontal cortex to lateral habenula pathway activity mediates chronic stress-induced depressive and anxiety-like behaviors17
In memoriam—Donald A. Overton, Ph.D17
Identifying brain-penetrant small-molecule modulators of human microglia using a cellular model of synaptic pruning17
Sex and sensitive period differences in potential effects of maltreatment on axial versus radial diffusivity in the corpus callosum17
Cannabidiol mitigates alcohol dependence and withdrawal with neuroprotective effects in the basolateral amygdala and striatum17
Modulation of learning safety signals by acute stress: paraventricular thalamus and prefrontal inhibition16
Control of dopamine communication by opioids: glutamate enters the discussion16
Extended course accelerated intermittent theta burst stimulation as a substitute for depressed patients needing electroconvulsive therapy16
Identifying novel proteins for suicide attempt by integrating proteomes from brain and blood with genome-wide association data16
In Memoriam: Terry A. Ketter, MD16
Social isolation and aggression training lead to escalated aggression and hypothalamus-pituitary-gonad axis hyperfunction in mice16
A review of diffusion MRI in mood disorders: mechanisms and predictors of treatment response16
The anxiogenic drug yohimbine is a reinforcer in male and female rats16
Local and global effects of sedation in resting-state fMRI: a randomized, placebo-controlled comparison between etifoxine and alprazolam16
Aversion-induced dopamine reductions predict drug-taking and escape behaviors16
Unexpected circuit-level tradeoffs in human stress resilience16
Refining the study of decision-making in animals: differential effects of d-amphetamine and haloperidol in a novel touchscreen-automated Rearing-Effort Discounting (RED) task and the Fixed-Ratio Effor16
Selective KOR antagonist alters functional patch sizes in individualized brain system: results from the Fast-fail Trial in Mood and Anxiety Spectrum Disorders (FAST-MAS)16
Demand for heroin in rats: effects of non-drug alternative substitutes and complements16
Robust aversive effects of trace amine-associated receptor 1 activation in mice16
Opioid-blunted cortisol response to stress is associated with increased negative mood and wanting of social reward16
The promise of precision functional mapping for neuroimaging in psychiatry15
Large-scale structural network change correlates with clinical response to rTMS in depression15
The impact of collider bias on genetic prediction in psychotic disorders15
Sex-specific resting state brain network dynamics in patients with major depressive disorder15
Neural underpinnings of open-label placebo effects in emotional distress15
Ro 64-6198, a selective NOP receptor agonist attenuates social impairments associated with NTG-induced migraine pain15
Pharmacological stimulation of infralimbic cortex after fear conditioning facilitates subsequent fear extinction15
Functional genomics identify causal variant underlying the protective CTSH locus for Alzheimer’s disease15
Comparative acute effects of mescaline, lysergic acid diethylamide, and psilocybin in a randomized, double-blind, placebo-controlled cross-over study in healthy participants15
Concerted elevations of cortical and striatal glutamate and GABA in antipsychotic-free individuals at clinical high-risk for psychosis15
Peptidomimetic inhibitors targeting TrkB/PSD-95 signaling improves cognition and seizure outcomes in an Angelman Syndrome mouse model15
Nucleus of the solitary tract A2 neurons control feeding behaviors via projections to the paraventricular hypothalamus15
Publisher Correction to: Trace amine-associated receptor 1 agonism promotes wakefulness without impairment of cognition in Cynomolgus macaques14
IN MEMORIAM Ghanshyam Narayan Pandey 1937–202214
Beyond the hypothalamus: roles for insulin as a regulator of neurotransmission, motivation, and feeding14
Absence of TAAR1 function increases methamphetamine-induced excitability of dorsal raphe serotonin neurons and drives binge-level methamphetamine intake14
Random forest and Shapley Additive exPlanations predict oxytocin targeted effects on brain functional networks involved in salience and sensorimotor processing, in a randomized clinical trial in autis14
Common side effects of MDMA-assisted psychotherapy14
In memoriam – George R. Breese, Ph.D14
Reply to Ploderl and Hengartner: learning about the course of suicidal behavior but not about the effects of SSRIs14
Pathways link environmental and genetic factors with structural brain networks and psychopathology in youth14
Unique and joint associations of polygenic risk for major depression and opioid use disorder with endogenous opioid system function14
Retraction Note: Predator odor increases avoidance and glutamatergic synaptic transmission in the prelimbic cortex via corticotropin-releasing factor receptor 1 signaling14
Is the stereoisomer R-MDMA a safer version of MDMA?14
ACNP 63rd Annual Meeting: Panels, Mini-Panels and Study Groups14
A projection from the medial prefrontal cortex to the lateral septum modulates coping behavior on the shock-probe test14
Correction: Lateral habenula induces cognitive and affective dysfunctions in mice with neuropathic pain via an indirect pathway to the ventral tegmental area14
Lateral habenula induces cognitive and affective dysfunctions in mice with neuropathic pain via an indirect pathway to the ventral tegmental area13
Dopamine D2 receptors in nucleus accumbens cholinergic interneurons increase impulsive choice13
The effects of D-Cycloserine on corticospinal excitability after repeated spaced intermittent theta-burst transcranial magnetic stimulation: A randomized controlled trial in healthy individuals13
To indulge or enrich: how environmental enrichment affects neurons that promote food seeking13
Exploring the role of mu opioid receptors in the therapeutic potential and abuse liability of (S)-ketamine13
The effect of selective nigrostriatal dopamine excess on behaviors linked to the cognitive and negative symptoms of schizophrenia13
Serum amyloid P component (SAP) modulates antidepressant effects through promoting membrane insertion of the serotonin transporter13
Acute, chronic and conditioned effects of intranasal oxytocin in the mu-opioid receptor knockout mouse model of autism: Social context matters13
Selective 5HT3 antagonists and sensory processing: a systematic review13
Targeting depression circuitry with H1 coil Transcranial Magnetic Stimulation: a retrospective circuit mapping study13
Change in brain molecular landscapes following electrical stimulation of the nucleus accumbens13
Isradipine augmentation of virtual reality cue exposure therapy for tobacco craving: a triple-blind randomized controlled trial13
Knockdown of USP22 alleviates LPS-induced microglial inflammation and mouse depressive-like behaviors via KAT2A13
Reliable variability in subjective responses to parenteral hydromorphone administration: empirical confirmation of an opioid non-responder phenotype13
PACAP regulates neuroendocrine and behavioral stress responses via CRF-containing neurons of the rat hypothalamic paraventricular nucleus13
Timing matters: modeling the effects of gestational cannabis exposure on social behavior and microglia in the developing amygdala13
ACNP 61st Annual Meeting: Poster Abstracts P271-P54013
Acute effects of MDMA, MDA, lysine-MDMA, and lysine-MDA in a randomized, double-blind, placebo-controlled, crossover trial in healthy participants13
Testosterone eliminates strategic prosocial behavior through impacting choice consistency in healthy males13
Sex-related differences in violence exposure, neural reactivity to threat, and mental health13
In Memoriam Bernard Agranoff12
Cocaine self-administration in adult female and male rhesus monkeys: longitudinal comparison with adolescent behavior and role of early life stress12
In memoriam: Kenneth E. Moore12
Transcriptomics in the nucleus accumbens shell reveal sex- and reinforcer-specific signatures associated with morphine and sucrose craving12
The Cognitive–Affective Social Processing and Emotion Regulation (CASPER) model12
Kappa opioid receptors as modulators of novelty processing12
ACNP 60th Annual Meeting: Poster Abstracts P551 – P83012
A meta-analysis of conditioned fear generalization in anxiety-related disorders12
In Memoriam: Burton M. Angrist, MD12
Childhood family environment and μ-opioid receptor availability in vivo in adulthood12
Xanomeline restores endogenous nicotinic acetylcholine receptor signaling in mouse prefrontal cortex12
A large-scale c-Fos brain mapping study on extinction of cocaine-primed reinstatement12
Towards causal inference-based antidepressant selection with brain and blood biomarkers12
The neural and psychophysiological effects of cannabidiol in youth with alcohol use disorder: A randomized controlled clinical trial12
Electronic health records and stratified psychiatry: bridge to precision treatment?12
Disentangling the roles of dopamine and noradrenaline in the exploration-exploitation tradeoff during human decision-making12
Ghrelin decreases sensitivity to negative feedback and increases prediction-error related caudate activity in humans, a randomized controlled trial12
Targeting inhibitory control in youth irritability: challenges and opportunities12
Integrating human brain proteomic data with genome-wide association study findings identifies novel brain proteins in substance use traits12
Kappa opioid receptor control of motivated behavior revisited12
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