Neuropsychopharmacology

Article	Citations
Synaptic plasticity as a therapeutic target to modulate circuits in psychiatric disorders	721
IN MEMORIAM - Irwin Feinberg, MD	329
Is the stereoisomer R-MDMA a safer version of MDMA?	329
A projection from the medial prefrontal cortex to the lateral septum modulates coping behavior on the shock-probe test	184
ACNP 60th Annual Meeting: Keyword Index	165
IN MEMORIAM: Floyd E. Bloom, M.D	151
Cocaine and amphetamine regulated transcript (CART) mediates sex differences in binge drinking through central taste circuits	147
Bayesian dynamical system analysis of the effects of methylphenidate in children with attention-deficit/hyperactivity disorder: a randomized trial	145
Foraging with the frontal cortex: A cross-species evaluation of reward-guided behavior	131
Amplitude-determined seizure-threshold, electric field modeling, and electroconvulsive therapy antidepressant and cognitive outcomes	128
Rostral anterior cingulate network effective connectivity in depressed adolescents and associations with treatment response in a randomized controlled trial	128
Novel non-stimulants rescue hyperactive phenotype in an adgrl3.1 mutant zebrafish model of ADHD	122
Adolescent social isolation induces distinct changes in the medial and lateral OFC-BLA synapse and social and emotional alterations in adult mice	99
Prefrontal allopregnanolone mediates the adverse effects of acute stress in a mouse model of tic pathophysiology	96
Rapid-acting antidepressants and the circadian clock	91
A meta-analysis of conditioned fear generalization in anxiety-related disorders	87
Quantitative standardization of resident mouse behavior for studies of aggression and social defeat	85
Early life stress is associated with greater negative emotionality and peripheral inflammation in alcohol use disorder	80
Misconfigured striatal connectivity profiles in smokers	78
Thinner cortices in high-risk offspring: the promises of big data	75
ACNP 62nd Annual Meeting: Keyword Index	71
The Brain & Behavior Research Foundation’s philanthropic support for neuropsychiatric research	70
ACNP 61st Annual Meeting: Poster Abstracts P541 – P809	67
Pramipexole modulates fronto-subthalamic pathway in sequential working memory	66
ACNP 61st Annual Meeting: Panels, Mini-Panels and Study Groups	66

IN MEMORIAM Ghanshyam Narayan Pandey 1937–2022	65
ACNP 61st Annual Meeting: Poster Abstracts P271-P540	62
Residual deficits in functional brain activity after chronic cocaine self-administration in rhesus monkeys	61
ACNP 62nd Annual Meeting: Author Index	59
A new prism next to motherhood’s light: uncovering changes in neural function following childbirth	59
Correction: Stress-induced generalization of negative memories is mediated by an extended hippocampal circuit	58
Sensitive period-regulating genetic pathways and exposure to adversity shape risk for depression	58
Orexin modulation of stress reactivity as a novel targeted treatment for anxiety and alcohol use disorder	55
Absence of TAAR1 function increases methamphetamine-induced excitability of dorsal raphe serotonin neurons and drives binge-level methamphetamine intake	54
Potentiation of AMPA receptors for rapid therapeutic gain in psychiatry has reached a new level of excitement	54
Multivariate patterns among multimodal neuroimaging and clinical, cognitive, and daily functioning characteristics in bipolar disorder	54
Epac2 activation drives calcium permeable-AMPA receptor accumulation, fueling the incubation of cocaine craving	53
Protein interacting with C-kinase 1 (PICK1) regulates synaptic function and reversal learning in a mouse model for schizophrenia	52
Endocannabinoid contributions to the perception of socially relevant, affective touch in humans	51
Fentanyl-induced hyperalgesia and analgesic tolerance in male rats: common underlying mechanisms and prevention by a polyamine deficient diet	51
Deconstructing dissociation: a triple network model of trauma-related dissociation and its subtypes	50
Is treatment-resistant schizophrenia a neuroimmune condition? Meta-analytic evidence from magnetic resonance spectroscopy	49
Beyond the hypothalamus: roles for insulin as a regulator of neurotransmission, motivation, and feeding	49
Delayed estrogen actions diminish food consumption without changing food approach, motor activity, or hypothalamic activation elicited by corticostriatal µ-opioid signaling	47
Leveraging large-scale brain networks in rats to understand neurological and psychiatric disorders in humans	47
Human neuroimaging and antipsychotic neurobiology at millisecond temporal resolution	47
The role of endogenous opioids in mindfulness and sham mindfulness-meditation for the direct alleviation of evoked chronic low back pain: a randomized clinical trial	46
Transdiagnostic evaluation of epigenetic age acceleration and burden of psychiatric disorders	45
Increasing ecological validity in neuropsychopharmacology research on the relationship between alcohol use and uncertain stressors	45
Exploring the role of mu opioid receptors in the therapeutic potential and abuse liability of (S)-ketamine	44
Does acute stress play a role in the lasting therapeutic effects of psychedelic drugs?	44
Transcranial focused ultrasound (tFUS): a promising noninvasive deep brain stimulation approach for pain	42
Development disturbed: sex-specific transcriptional alterations in adolescent mice after perinatal fentanyl exposure	42
Leveraging AI to predict substance use disorder treatment outcomes	41
The national institute on drug abuse diversity scholars network: success for a diverse addiction science workforce	41
Electronic health records and stratified psychiatry: bridge to precision treatment?	41
C-reactive protein moderates associations between racial discrimination and ventromedial prefrontal cortex activation during attention to threat in Black American women	40
TAAR1 agonist ulotaront modulates striatal and hippocampal glutamate function in a state-dependent manner	40
Correction: High-intensity sweet taste as a predictor of subjective alcohol responses to the ascending limb of an intravenous alcohol prime: an fMRI study	40
Comparable roles for serotonin in rats and humans for computations underlying flexible decision-making	39
Spotlighting SHAPERS: sex hormones associated with psychological and endocrine roles	39
Academic ethics of mental health: the national black postdocs framework for the addressment of support for undergraduate and graduate trainees	39
Comparison of brain nicotine accumulation from traditional combustible cigarettes and electronic cigarettes with different formulations	38
Potential therapeutics for effort-related motivational dysfunction: assessing novel atypical dopamine transport inhibitors	38
Retraction Note: Predator odor increases avoidance and glutamatergic synaptic transmission in the prelimbic cortex via corticotropin-releasing factor receptor 1 signaling	38
Reply to Sun: Dynamic and accessible pharmacogenomic results: a response to pharmacogenomic testing for antidepressant treatment selection	37
Role of the histone variant H2A.Z.1 in memory, transcription, and alternative splicing is mediated by lysine modification	37
Matrix metalloproteinase 9 (MMP-9) activity, hippocampal extracellular free water, and cognitive deficits are associated with each other in early phase psychosis	37
Estimating the direct effects of the genetic liabilities to bipolar disorder, schizophrenia, and behavioral traits on suicide attempt using a multivariable Mendelian randomization approach	36
Reactivation of encoding ensembles in the prelimbic cortex supports temporal associations	36
Enhanced cognitive flexibility and phasic striatal dopamine dynamics in a mouse model of low striatal tonic dopamine	36
Isradipine augmentation of virtual reality cue exposure therapy for tobacco craving: a triple-blind randomized controlled trial	36
Distinct roles of excitatory and inhibitory neurons in the medial prefrontal cortex in the expression and reconsolidation of methamphetamine-associated memory in male mice	36
Author Correction: Sex differences in offspring risk and resilience following 11β-hydroxylase antagonism in a rodent model of maternal immune activation	36
Cognitive performance as a behavioral phenotype associated with cocaine self-administration in female and male socially housed monkeys	35

Effects of psychedelic, DOI, on nucleus accumbens dopamine signaling to predictable rewards and cues in rats	35
Validation of a non-food or water motivated effort-based foraging task as a measure of motivational state in male mice	35
Acute, chronic and conditioned effects of intranasal oxytocin in the mu-opioid receptor knockout mouse model of autism: Social context matters	34
Investigating cross-sectional and longitudinal relationships between brain structure and distinct dimensions of externalizing psychopathology in the ABCD sample	33
Dorsal raphe to basolateral amygdala corticotropin-releasing factor circuit regulates cocaine-memory reconsolidation	33
Mitogen-activated protein kinase dependent presynaptic potentiation in the lateral habenula mediates depressive-like behaviors in rats	33
Publisher Correction: Ketamine reduces the neural distinction between self- and other-produced affective touch: a randomized double-blind placebo-controlled study	32
PACAP regulates neuroendocrine and behavioral stress responses via CRF-containing neurons of the rat hypothalamic paraventricular nucleus	32
Tricyclic and tetracyclic antidepressants upregulate VMAT2 activity and rescue disease-causing VMAT2 variants	32
In memoriam – George R. Breese, Ph.D	31
Pre- and postsynaptic signatures in the prelimbic cortex associated with “alcohol use disorder” in the rat	30
Morphine, the microbiome, and fatty acids: short chains make a big link in opioid reward	30
Pediatric PTSD is characterized by age- and sex-related abnormalities in structural connectivity	30
Common side effects of MDMA-assisted psychotherapy	30
Sex differences in offspring risk and resilience following 11β-hydroxylase antagonism in a rodent model of maternal immune activation	29
A dubious distinction for females: rapid achievement of prefrontal cortical hypoactivity and cognitive deficit upon remifentanil self-administration	29
Early-life oxytocin attenuates the social deficits induced by caesarean-section delivery in the mouse	29
The effects of experience of discrimination and acculturation during pregnancy on the developing offspring brain	29
Bridging the gap: preparing the next generation of brain scientists to communicate with the general public and lawmakers	29
Correction: Organization of the social cognition network predicts future depression and interpersonal impairment: a prospective family-based study	28
Mapping causal generators of appetitive motivation-hedonic functions in frontal cortex	28
Publisher Correction to: Trace amine-associated receptor 1 agonism promotes wakefulness without impairment of cognition in Cynomolgus macaques	28
Pathways link environmental and genetic factors with structural brain networks and psychopathology in youth	28
The evolution of the psychedelic revolution	28
Gestational ethanol exposure impairs motor skills in female mice through dysregulated striatal dopamine and acetylcholine function	28
Testosterone eliminates strategic prosocial behavior through impacting choice consistency in healthy males	28
The effect of selective nigrostriatal dopamine excess on behaviors linked to the cognitive and negative symptoms of schizophrenia	28
Placebo response in RCT for antidepressant may not always be the ‘villain’ to fight: are KOR antagonists possibly affecting the intrinsic placebo response?	27
Endogenous dopamine release in the human brain as a pharmacodynamic biomarker: evaluation of the new GPR139 agonist TAK-041 with [11C]PHNO PET	27
A sex-specific role for the bed nucleus of the stria terminalis in proactive defensive behavior	27
Mismatch negativity as an index of target engagement for excitation/inhibition-based treatment development: a double-blind, placebo-controlled, randomized, single-dose cross-over study of the serotoni	27
Systemic kappa opioid receptor antagonism accelerates reinforcement learning via augmentation of novelty processing in male mice	27
Reply to Ploderl and Hengartner: learning about the course of suicidal behavior but not about the effects of SSRIs	26
Not all smokers are alike: the hidden cost of sustained attention during nicotine abstinence	26
Single doses of a highly selective inhibitor of phosphodiesterase 1 (lenrispodun) in healthy volunteers: a randomized pharmaco-fMRI clinical trial	26
Cocaine restricts nucleus accumbens feedforward drive through a monoamine-independent mechanism	26
Chronic sodium bromide treatment relieves autistic-like behavioral deficits in three mouse models of autism	26
Crossing diagnostic boundaries to understand the genetic etiology of addiction	26
Medial orbitofrontal cortex and nucleus accumbens mediation in risk assessment behaviors in adolescents and adults	26
Repeated methamphetamine administration produces cognitive deficits through augmentation of GABAergic synaptic transmission in the prefrontal cortex	25
Correction to: Isoform-selective phosphoinositide 3-kinase inhibition ameliorates a broad range of fragile X syndrome-associated deficits in a mouse model	25
Correction to: Intra-individual variability and stability of affect and craving among individuals receiving medication treatment for opioid use disorder	25
Unique and joint associations of polygenic risk for major depression and opioid use disorder with endogenous opioid system function	25
Epigenetic aging in psychiatry: clinical implications and therapeutic opportunities	24
Patient-specific connectomic models correlate with, but do not reliably predict, outcomes in deep brain stimulation for obsessive-compulsive disorder	24
GABAA and NMDA receptor density alterations and their behavioral correlates in the gestational methylazoxymethanol acetate model for schizophrenia	24
Selective 5HT3 antagonists and sensory processing: a systematic review	24
Using metabolic imaging to investigate neuromodulatory mechanisms of rTMS	24
Randomized controlled experimental study of hydrocortisone and D-cycloserine effects on fear extinction in PTSD	24
Cell-type specific synaptic plasticity in dorsal striatum is associated with punishment-resistance compulsive-like cocaine self-administration in mice	24
How much is too much? New evidence associating low levels of prenatal alcohol exposure with brain differences in children	24
Sex-related differences in violence exposure, neural reactivity to threat, and mental health	24
Targeted and transient opening of the blood brain barrier in discrete neurocircuits and brain regions	24
Serum amyloid P component (SAP) modulates antidepressant effects through promoting membrane insertion of the serotonin transporter	24
Altered neuronal activity in the ventromedial prefrontal cortex drives nicotine intake escalation	23
Rac1 GTPase activation impairs fear conditioning-induced structural changes in basolateral amygdala neurons and long-term fear memory formation	23
Anandamide and 2-arachidonoylglycerol differentially modulate autistic-like traits in a genetic model of autism based on FMR1 deletion in rats	23
Plasticity markers in the human brain associated with rapid antidepressants	23
Ethanol blocks a novel form of iLTD, but not iLTP of inhibitory inputs to VTA GABA neurons	23
The National Institute on Drug Abuse Summer Research Internship Program: Building a Diverse National Scientific Workforce	23
Silencing KCC2 in mouse dorsal hippocampus compromises spatial and contextual memory	23
Correction: Neutralization of tumor necrosis factor-related apoptosis-inducing ligand reduces spinal cord injury damage in mice	22
Dopamine D2 receptors in nucleus accumbens cholinergic interneurons increase impulsive choice	22
The times they are a-changin’: new co-principal editors at NPP	22
Muscarinic receptor activation overrides boundary conditions on memory updating in a calcium/calmodulin-dependent manner	22
Cell type and sex specific insights into ventral striatum deep brain stimulation for cocaine relapse	22
ACNP 63rd Annual Meeting: Panels, Mini-Panels and Study Groups	22
How should we design future mechanistic and/or efficacy clinical trials?	22
Compulsion and substance use disorder: potential importance of boundary conditions	22
In remembrance of Herbert Pardes, M.D. July 7, 1934–April 30, 2024	21
LC-derived excitatory synaptic transmission to dorsal raphe serotonin neurons is inhibited by activation of alpha2-adrenergic receptors	21
Inhibition of striatal indirect pathway during second postnatal week leads to long-lasting deficits in motivated behavior	21
A double-blind, randomized controlled study of the effects of celecoxib on clinical symptoms and cognitive impairment in patients with drug-naïve first episode schizophrenia: pharmacogenetic impact of	21
ACNP 63rd Annual Meeting: Poster Abstracts P1-P304	21
Data-driven connectivity profiles relate to smoking cessation outcomes	21
Network-based drug repurposing for schizophrenia	20
How electroconvulsive therapy works in the treatment of depression: is it the seizure, the electricity, or both?	20
Racial discrimination associates with lower cingulate cortex thickness in trauma-exposed black women	20
It’s about racism, not race: a call to purge oppressive practices from neuropsychiatry and scientific discovery	20
Anterior cingulate cortex activation during attentional control as a transdiagnostic marker of psychotherapy response: a randomized clinical trial	20

Acute administration of ketone beta-hydroxybutyrate downregulates 7T proton magnetic resonance spectroscopy-derived levels of anterior and posterior cingulate GABA and glutamate in healthy adults	20
Deficits in integrative NMDA receptors caused by Grin1 disruption can be rescued in adulthood	20
Life extension factor klotho regulates behavioral responses to stress via modulation of GluN2B function in the nucleus accumbens	20
mGluR5 PAMs rescue cortical and behavioural defects in a mouse model of CDKL5 deficiency disorder	20
Hippocampus and amygdala fear memory engrams re-emerge after contextual fear relapse	20
Novel approaches to estimate prefrontal synaptic strength in vivo in humans: of relevance to depression, schizophrenia, and ketamine	20
The GABAA receptor modulator zolpidem augments hippocampal-prefrontal coupling during non-REM sleep	20
Insular cortex corticotropin-releasing factor integrates stress signaling with social affective behavior	20
Normalization of impaired emotion inhibition in bipolar disorder mediated by cholinergic neurotransmission in the cingulate cortex	19
Efficacy and safety of aticaprant, a kappa receptor antagonist, adjunctive to oral SSRI/SNRI antidepressant in major depressive disorder: results of a phase 2 randomized, double-blind, placebo-control	19
Sex-specific nicotine sensitization and imprinting of self-administration in rats inform GWAS findings on human addiction phenotypes	19
Overdose mortality rates for opioids and stimulant drugs are substantially higher in men than in women: state-level analysis	19
Epac2-mediated synaptic insertion of Ca2+-permeable AMPARs in the nucleus accumbens contributes to incubation of cocaine craving	19
Novel neurosteroid therapeutics for post-partum depression: perspectives on clinical trials, program development, active research, and future directions	18
Genome-wide association study accounting for anticholinergic burden to examine cognitive dysfunction in psychotic disorders	18
Functional connectivity of salience and affective networks among remitted depressed patients predicts episode recurrence	18
AM6527, a neutral CB1 receptor antagonist, suppresses opioid taking and seeking, as well as cocaine seeking in rodents without aversive effects	18
Parvalbumin interneuron mGlu5 receptors govern sex differences in prefrontal cortex physiology and binge drinking	18
Polygenic liability for antipsychotic dosage and polypharmacy - a real-world registry and biobank study	18
The effects of D-Cycloserine on corticospinal excitability after repeated spaced intermittent theta-burst transcranial magnetic stimulation: A randomized controlled trial in healthy individuals	18
Role of neuropeptide neuromedin U in the nucleus accumbens shell in cocaine self-administration in male rats	18
Neuroimaging in schizophrenia: an overview of findings and their implications for synaptic changes	17
Leveraging ultra-high field (7T) MRI in psychiatric research	17
Lateral habenula induces cognitive and affective dysfunctions in mice with neuropathic pain via an indirect pathway to the ventral tegmental area	17
Prefrontal-hippocampal interactions supporting the extinction of emotional memories: the retrieval stopping model	17
Prenatal opioid exposure inhibits microglial sculpting of the dopamine system selectively in adolescent male offspring	17
Prefrontal cortex interactions with the amygdala in primates	17
NIMH perspectives on future directions in neuroimaging for mental health	17
Fetal behavior and gestational serotonin reuptake inhibitor exposure: relationships between behavior, drug dosage, plasma drug level, and a measure of drug bioeffect	17
Revisiting the role of computational neuroimaging in the era of integrative neuroscience	17
Selective serotonin reuptake inhibitors and suicidal behaviour: a population-based cohort study	17
Neurotrophic effects of potentiating gaba-mediated dendritic inhibition	17
Psychiatric neuroimaging designs for individualised, cohort, and population studies	17
Does cannabidiol make cannabis safer? A randomised, double-blind, cross-over trial of cannabis with four different CBD:THC ratios	17
Reward-related predictors of symptom change in behavioral activation therapy for anhedonic adolescents: a multimodal approach	16
IN MEMORIAM—Jan Fawcett, MD	16
A digital intervention for cognitive deficits following COVID-19: a randomized clinical trial	16
In Memoriam: Gian Carlo Salmoiraghi, D.Sc., MD, Ph.D.	16
IN MEMORIAM John Gary Csernansky 1954–2022	16
Dynamic activity of interpeduncular nucleus GABAergic neurons controls expression of nicotine withdrawal in male mice	16
Examining the association between posttraumatic stress disorder and disruptions in cortical networks identified using data-driven methods	16
ACNP 60th Annual Meeting: Author Index	16
Acute effects of R-MDMA, S-MDMA, and racemic MDMA in a randomized double-blind cross-over trial in healthy participants	16
ACNP 62nd Annual Meeting: Poster Abstracts P501 – P753	16
Brain reactivity to nicotine cues mediates the link between resting-state connectivity and cue-induced craving in individuals who smoke or vape nicotine	16
Towards an understanding of psychedelic-induced neuroplasticity	16
ACNP 60th Annual Meeting: Poster Abstracts P551 – P830	16
In Memoriam Bernard Agranoff	16
PET imaging in rat brain shows opposite effects of acute and chronic alcohol exposure on phosphodiesterase-4B, an indirect biomarker of cAMP activity	16
Ketamine induced synaptic plasticity operates independently of long-term potentiation	16
Basal forebrain cholinergic signaling in the basolateral amygdala promotes strength and durability of fear memories	16
Organization of the social cognition network predicts future depression and interpersonal impairment: a prospective family-based study	15
In Memoriam: Burton M. Angrist, MD	15
Neuroimaging in psychiatry: toward mechanistic insights and clinical utility	15
Applying fetal, infant, and toddler (FIT) neuroimaging to understand mental health	15
Identifying novel proteins underlying loneliness by integrating GWAS summary data with human brain proteomes	15
In memoriam: Dr. Thomas Lehner	15
Psychosocial moderators of polygenic risk scores of inflammatory biomarkers in relation to GrimAge	15
IN MEMORIAM: James C. Harris, MD (1940–2021)	15
Democratizing technologies in psychiatry: non-human primate neuroanatomy paves the way for accessible neurofeedback in the wild	15
Therapeutic potential of N-methyl-D-aspartate receptor modulators in psychiatry	15
In Memoriam: Dr. James B. Appel	15
Stimulant medications in children with ADHD normalize the structure of brain regions associated with attention and reward	15
A covert cortical ensemble for learned fear suppression	15
Shaping long-range functional connectivity through prefrontal interneuron plasticity	15
Distributed circuits regulating defensive state transitions: freezing, flight and fight	15
Potential applications of temporal interference deep brain stimulation for the treatment of transdiagnostic conditions in psychiatry	15
In memoriam: Kenneth E. Moore	15
Pharmacological and genetic manipulations at the µ-opioid receptor reveal arrestin-3 engagement limits analgesic tolerance and does not exacerbate respiratory depression in mice	14
Repurposing anti-inflammatory medications for alcohol and substance use disorders	14
Correction: Digital and precision clinical trials: innovations for testing mental health medications, devices, and psychosocial treatments	14
Ventral prefrontal network response to alcohol in young adults with bipolar disorder: a within-subject randomized placebo-controlled alcohol administration study	14
Modulation of hippocampal activity in schizophrenia with levetiracetam: a randomized, double-blind, cross-over, placebo-controlled trial	14
In memoriam: Eugene S Paykel, MD, FRCP, FRCPsych, FMedSci	14
Moving beyond descriptive nosology: an argument for negative valence systems disorder	14
Cell type specific focused ultrasound neuromodulation in preclinical models of sleep and psychiatric disorders	14
A path to novel, effective treatments for schizophrenia	14
Comparative rhythmic transcriptome profiling of human and mouse striatal subregions	13
Basolateral amygdala neuropeptide Y system modulates binge ethanol consumption	13
Basal forebrain-lateral habenula inputs and control of impulsive behavior	13
Kappa opioid receptor availability predicts severity of anhedonia in schizophrenia	13
Differentiating white matter measures that protect against vs. predispose to bipolar disorder and other psychopathology in at-risk youth	13
A large-scale c-Fos brain mapping study on extinction of cocaine-primed reinstatement	13
Correction: Voltage-gated potassium channels control extended access cocaine seeking: a role for nucleus accumbens astrocytes	13
Calcitonin receptor signal: a potential target for opioid use disorder?	13
Advances in precision neuromodulation: electroconvulsive therapy amplitude titration	13
NPP Editorial: tides of progress	13
Identification of novel genetic loci and candidate genes for progressive ethanol consumption in diversity outbred mice	13
Systematic misestimation of machine learning performance in neuroimaging studies of depression	13
Correction: The effects of experience of discrimination and acculturation during pregnancy on the developing offspring brain	13
Oxytocin treatment rescues irritability-like behavior in Cc2d1a conditional knockout mice	13
Sex differences in sensitivity to dopamine receptor manipulations of risk-based decision making in rats	13
In Memoriam: Larry J. Young, PhD	13
Endocannabinoid interference blocks post-global cerebral ischemia depression through prefrontal cortico-amygdala projections	13
Reply to Winter et al: Interpreting weights of multimodal machine learning models—problems and pitfalls	13