OOIR: Observatory of International Research

Papers

(The median citation count of Chemical Research in Toxicology is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
Elevating Research and Careers in the Development of Safer Drugs through Artificial Intelligence	107
Oxidative Deformylation of the Predominant DNA Lesion 5-Formyl-2′-deoxyuridine	104
Application of Covalent Binding Body Burden in the HμREL Human Hepatocyte Coculture Model for Reactivity Risk Assessment of Metabolically Low Turnover Drugs	83
Recent Advances in DNA Lesion Mapping and Repair Mechanisms	72
Issue Publication Information	65
Issue Publication Information	59
Issue Editorial Masthead	57
Issue Editorial Masthead	56
Surfactant Coformulants in Glyphosate-Based Herbicides: Current Gaps, and Paths Forward in Human Biomonitoring	55
A Weakly Supervised Deep Learning Framework for Whole Slide Classification to Facilitate Digital Pathology in Animal Study	54
Identification of an Epoxide Metabolite of Amitriptyline In Vitro and In Vivo	50
Bioaccumulation and DNA Adduct Formation of Aristolactam I: Unmasking a Toxicological Mechanism in the Pathophysiology of Aristolochic Acid Nephropathy	50
Advances in Metabolism and Metabolic Toxicology of Quinoxaline 1,4-Di-N-oxides	50
Capture of Electrophilic Quinones in the Extracellular Space: Evidence for a Phase Zero Reaction	48
Systematic Investigation of CYP3A4 Using Side-by-Side Comparisons of Apo, Active Site, and Allosteric-Bound States	46
LA-ICP-MS and Immunohistochemical Staining with Lanthanide-Labeled Antibodies to Study the Uptake of CeO₂ Nanoparticles by Macrophages in Tissue Sections	45
Coumarin-Based Noncytotoxicity Fluorescent Dye for Tracking Actin Protein in In-Vivo Imaging	44
Structure–Activity Relationship of Protein-Mediated Molecular Initiating Events of Organ-Specific Toxicities	42
Mechanistic Insights into Toxicity of Titanium Dioxide Nanoparticles at the Micro- and Macro-levels	40
Predicting Liver-Related In Vitro Endpoints with Machine Learning to Support Early Detection of Drug-Induced Liver Injury	39
Protein Haptenation and Its Role in Allergy	38
Cellular Interactions and Fatty Acid Transporter CD36-Mediated Uptake of Per- and Polyfluorinated Alkyl Substances (PFAS)	37
Alternaria alternata Mycotoxins Activate the Aryl Hydrocarbon Receptor and Nrf2-ARE Pathway to Alter the Structure and Immune Response of Colon Epithelial Cells	36
A Review on the Recent Applications of Deep Learning in Predictive Drug Toxicological Studies	35
Dissecting the Enantioselective Neurotoxicity of Isocarbophos: Chiral Insight from Cellular, Molecular, and Computational Investigations	32

Issue Editorial Masthead	31
Issue Editorial Masthead	31
Response to ‘Comments on “Tobacco-Specific Nitrosamines in the Tobacco and Mainstream Smoke of Commercial Little Cigars”’ Letter to Editor	31
Issue Editorial Masthead	30
Characterization of Teicoplanin-Specific T-Cells from Drug Naïve Donors Expressing HLA-A*32:01	30
Issue Editorial Masthead	30
Federated Learning in Computational Toxicology: An Industrial Perspective on the Effiris Hackathon	30
Computational Prediction of Metabolic α-Carbon Hydroxylation Potential of N -Nitrosamines: Overcoming Data Limitations for Carcinogenicity Assessment	29
Photosensitized Oxidation of Free and Peptide Tryptophan to N-Formylkynurenine	29
2,2′,4,4′-Tetrabromodiphenyl Ether (PBDE 47) Selectively Stimulates Proatherogenic PPARγ Signatures in Human THP-1 Macrophages to Contribute to Foam Cell Formation	29
Structural Elucidation of Agrochemical Metabolic Transformation Products Based on Infrared Ion Spectroscopy to Improve In Silico Toxicity Assessment	28
Products Generated by Amine-Catalyzed Strand Cleavage at Apurinic/Apyrimidinic Sites in DNA: New Insights from a Biomimetic Nucleoside Model System	28
Modeling the Toxicokinetics of Suspensions of Soluble Metallic Nanomaterials	28
ZIM, a Norbornene Derived from 4-Aminoantipyrine, Induces DNA Damage and Cell Death but in Association Reduces the Effect of Commercial Chemotherapeutics	28
Prediction of Cytochrome P450 Substrates Using the Explainable Multitask Deep Learning Models	27
Potential Involvement of Sulfotransferase in the Mechanism of Lamotrigine-induced Skin Rash	27
Issue Publication Information	27
Mass Spectrometry-Based Metabolic Profiling of Urinary Metabolites of N′-Nitrosonornicotine (NNN) in the Rat	26
Leveraging Cell Painting Images to Expand the Applicability Domain and Actively Improve Deep Learning Quantitative Structure–Activity Relationship Models	26
Conditional Binding of Arsenic Trioxide (ATO) to Cysteine-Rich Zinc Finger Motifs within RBCC Domain of PML Protein	25
Nonclinical Safety Signals in PharmaPendium Improve the Predictability of Human Drug-Induced Liver Injury	25
HDAC6-Mediated NLRP3 Inflammasome Activation Is Involved in Nickel Nanoparticle-Induced Pulmonary Inflammation and Fibrosis	25
Predictive Modeling of DNA Damage Outcomes: Classification of Mutational Determinants Using Augmented Machine Learning Techniques	25
Quantum Mechanical Assessment of Nitrosamine Potency	24
LC–MS/MS Analysis of Reaction Products of Arginine/Methylarginines with Methylglyoxal/Glyoxal	24
Assessing the Toxicity of Terpene- and Amino Acid-Based Natural Deep Eutectic Solvents	24
The Toxicity of Poly(acrylonitrile-styrene–butadiene) Microplastics toward Hyalella azteca Is Associated with Biofragmentation and Oxidative Stress	24
Issue Editorial Masthead	23
Issue Publication Information	23
Quantum-Mechanical Approach to Predicting the Carcinogenic Potency of N -Nitroso Impurities in Pharmaceuticals	23
Advancing Drug Safety in Drug Development: Bridging Computational Predictions for Enhanced Toxicity Prediction	23
Zebrafish Larvae as a Predictive Model for the Risk of Chemical-Induced Cholestasis: Phenotypic Evaluation and Nomogram Formation	22
Nucleophilic Thiol Proteins Bind Covalently to Abasic Sites in DNA	22
Free Radicals in Little Cigar Mainstream Smoke and the Potential Influence of Flavoring Chemicals on Free Radical Production	22
Acrylamide-Aggravated Liver Injury by Activating Endoplasmic Reticulum Stress in Female Mice with Diabetes	22
Capturing Differential Quality of Experimental Evidence in a Predictive Quantum-Mechanical Model for Respiratory Sensitization	22
Issue Publication Information	22
Detection of Trace Skin Sensitizers Using Novel Nucleophiles with Quaternary Ammonium by Liquid Chromatography–Mass Spectrometry	21
CYP3A4-Mediated Metabolic Activation and Cytotoxicity of Chlortoluron	21
Chemoproteomic Approach for Identifying Nuclear Arsenite-Binding Proteins	21
Photo-oxidation and Photoreduction of Catechols by Chlorophyll Metabolites and Methylene Blue	21
Circular RNAs: A Potential Regulator in Environmental Chemical Carcinogenesis	21
Integrative Data Mining Approach: Case Study with Adverse Outcome Pathway Network Leading to Pulmonary Fibrosis	21
Simultaneous Quantification of Biomarkers for Bis-(2-chloroethyl) Sulfide and 1,2-Bis(2-chloroethylthio) Ethane Exposure in Human Urine at Trace Exposure Levels by Gas Chromatography Tandem Mass Spect	20
Heterogeneous Oxidation Products of Fine Particulate Isoprene Epoxydiol-Derived Methyltetrol Sulfates Increase Oxidative Stress and Inflammatory Gene Responses in Human Lung Cells	20
Cytocompatibility of Ti₃C₂T_x MXene with Red Blood Cells and Human Umbilical Vein Endothelial Cells and the Underlying Mechanisms	20
Navigating Transcriptomic Connectivity Mapping Workflows to Link Chemicals with Bioactivities	20
Diethylhexyl Phthalate and Bisphenol A Promote Vincristine and Tamoxifen Resistancein Vitro	20
Melatonin Vapes Contain Potential Contaminants and Alter the Human Bronchial Epithelial Transcriptome	19
Call for Papers for a Special Issue on Mass Spectrometry Advances for Environmental and Human Health	19

Nontargeted Analysis in Tobacco Research: Challenges and Opportunities	19
Dopamine Release Impairments Accompany Locomotor and Cognitive Deficiencies in Rotenone-Treated Parkinson’s Disease Model Zebrafish	19
Aldehyde-Associated Mutagenesis─Current State of Knowledge	19
Deep Learning Models Compared to Experimental Variability for the Prediction of CYP3A4 Time-Dependent Inhibition	19
Black Raspberry Extract Enhances Glutathione Conjugation of the Fjord-Region Diol Epoxide Derived from the Tobacco Carcinogen Dibenzo[def,p]chrysene in Human Oral Cells	19
Characterization of a Novel Thermostable DNA Lyase Used To Prepare DNA for Next-Generation Sequencing	19
Correction to “Use of Structural Alerts for Reactive Metabolites in the Application SpotRM”	18
Binding of Per- and Polyfluoroalkyl Substances to β-Lactoglobulin from Bovine Milk	18
Increased JUUL Emissions from Initial Puffs after Removing and Reinserting Pod	18
A Photoinducible DNA Cross-Linking Agent with Potent Cytotoxicity and Selectivity Toward Triple-Negative Breast Cancer Cell Line	18
The Genotoxicity of Stress	18
Issue Editorial Masthead	18
Screening DNA Damage in the Rat Kidney and Liver by Untargeted DNA Adductomics	18
Issue Publication Information	18
Metabolic Activation and Cytotoxicity of Propafenone Mediated by CYP2D6	17
Introduction to the Special Issue: AI Meets Toxicology	17
Novel In Vitro Intestinal Microbiome Model to Study Lipidomic and Metabolomic Adaptations Due to Exposure to Glyphosate, Perfluorooctanoic Acid, and Docusate Sodium	17
RNA Oxidative Damage by the Iron-Fenton Reaction is Influenced by Bicarbonate Concentration and Ligand Strength	17
Natural Products in Redox Toxicology	17
Photosensitizing Properties of the Topical Retinoid Drug Adapalene	17
Cell Painting and Chemical Structure Read-Across Can Complement Each Other for Rat Acute Oral Toxicity Prediction in Chemical Early Derisking	17
Metabolomic Study on Iohexol-Induced Nephrotoxicity in Rats Based on NMR and LC–MS Analyses	17
Phthalate Exposure: Prevalence, Health Effects, Regulatory Frameworks, and Remediation	17
Role of Human Aldo–Keto Reductases in the Nitroreduction of 1-Nitropyrene and 1,8-Dinitropyrene	17
Issue Publication Information	16
Activation of V-Domain Immunoglobulin Suppressor of T-Cell Activation by Baloxavir Marboxil Ameliorates Systemic Lupus Erythematosus through Inhibiting Lysophosphatidylcholine/CD40 Ligand	16
Issue Editorial Masthead	16
New Aminobiphenylcysteine Derivatives in Globin and Urine of Rats Dosed with 4-Aminobiphenyl, a Tobacco Smoke Carcinogen	16
Correction to “Structure-Based Reactivity Profiles of Reactive Metabolites with Glutathione”	15
Profiling How the Gut Microbiome Modulates Host Xenobiotic Metabolism in Response to Benzo[a]pyrene and 1-Nitropyrene Exposure	15
Spatiotemporal Visualization of Paraquat Distribution, Toxicokinetics, and Its Detoxification in Zebrafish Using Matrix-Assisted Laser Desorption Ionization Mass Spectrometry Imaging	15
One-Week Kava Dietary Supplementation Increases Both Urinary N- and O-Glucuronides of NNAL, a Lung Carcinogen Major Metabolite, among Smokers	15
Idiosyncratic Drug Reactions: A 35-Year Chemical Research in Toxicology Perspective	15
Issue Publication Information	15
Issue Editorial Masthead	15
Computer-Aided Discovery and Redesign for Respiratory Sensitization: A Tiered Mechanistic Model to Deliver Robust Performance Across a Diverse Chemical Space	15
Facile Biological Oxidation of Dopamine to 6-Hydroxydopamine p-Quinone in a Sequential Two-Step Process: Implications for Parkinson’s Disease	14
Interindividual Variability in Cytochrome P450 3A and 1A Activity Influences Sunitinib Metabolism and Bioactivation	14
Cannabidiol Toxicity Driven by Hydroxyquinone Formation	14
Nicotine Dosimetry in Evaluating Electronic Cigarettes Compared to Cigarette Smoking: Implications for Tobacco Regulatory Science	14
Dissolution Rate of Nanomaterials Determined by Ions and Particle Size under Lysosomal Conditions: Contributions to Standardization of Simulant Fluids and Analytical Methods	14
Bioactivation of the β-Amyloid Precursor Protein-Cleaving Enzyme 1 Inhibitor Atabecestat Leads to Protein Adduct Formation on Glutathione S-Transferase Pi	14
Nrf2 Activation Mitigates Silver Nanoparticle-Induced Ferroptosis in Hepatocytes	14
Nuclear DNA and Mitochondrial Damage of the Cooked Meat Carcinogen 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in Human Neuroblastoma Cells	14
Furan Metabolites Are Elevated in Users of Various Tobacco Products and Cannabis	14
Mechanisms Mediating the Combined Toxicity of Paraquat and Maneb in SH-SY5Y Neuroblastoma Cells	14
Women in Toxicology Special Issue	14
Hazard Profiling of Commercially Relevant Quantum Dot Components Revealed Synergistic Interactions between Heavy Metals and Polymers	14
8-Oxo-2′-deoxyguanosine Replication in Mutational Hot Spot Sequences of the p53 Gene in Human Cells Is Less Mutagenic than That of the Corresponding Formamidopyrimidine	14
A Computational Approach for Respiratory Hazard Identification of Flavor Chemicals in Tobacco Products	14
Cadmium Exposure and Cardiovascular Diseases	14
Histotoxicity of AIEgen Based on Triphenylamine for the Simultaneous and Discriminatory Sensing of Hg²⁺ and Ag⁺ Directly in Aqueous Media for Environmental Applications	13
Examining Metal Contents in Primary and Secondhand Aerosols Released by Electronic Cigarettes	13
Human Keratinocyte Responses to Woodsmoke Chemicals	13
P38 MAPK, NF-κB, and JAK-STAT3 Signaling Pathways Involved in Capecitabine-Induced Hand-Foot Syndrome via Interleukin 6 or Interleukin 8 Abnormal Expression	13
Honoring Larry Marnett, Founding Editor of Chemical Research in Toxicology	13
Quantification of Intracellular DNA–Protein Cross-Links with N7-Methyl-2′-Deoxyguanosine and Their Contribution to Cytotoxicity	13
N-Doped Graphene for Biomedical Applications: A Comparative Biocompatibility Assessment of Green and Chemical Exfoliation	13
Liver and Intestinal Fatty Acid Binding Proteins Are Not Critical for Perfluorooctanesulfonate (PFOS) Tissue Distribution and Elimination in Mice	13
Tox24 Challenge	13
Interview with Professor Cynthia J. Burrows, 2022 Founders Award Winner, American Chemical Society Division of Chemical Toxicology	13
Modelling In vitro Mutagenicity Using Multi-Task Deep Learning and REACH Data	13
Recent Contributions of Mass Spectrometry-Based “Omics” in the Studies of Breast Cancer	13
Production of Peroxymonocarbonate by Steady-State Micromolar H₂O₂ and Activated Macrophages in the Presence of CO₂/HCO₃^– Evidenced by Boronate Pr	13
Chemoproteomic Approach for the Quantitative Identification of Arsenic-Binding Proteins	13
Chlorogenic Acid Alleviates Early-Life GenX Exposure-Induced Neurotoxicity via Decreasing Lipopolysaccharide-Induced Pyroptosis by the Systemic Translocation and Suppressing the PI3K/AKT/NF-κB Pathway	13
A New Explanation for the Mystery of Rasputin’s Survival of Cyanide Poisoning: Eating Raw Garlic	12
CYP2A6 Activity and Deuterated 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) Metabolism in Cigarette Smokers	12
Quantitation of Ten Urinary Nicotine Metabolites, Including 4-Hydroxy-4-(3-pyridyl) Butanoic Acid, a Product of Nicotine 2′-Oxidation, and CYP2A6 Activity in Japanese Americans, Native Hawaiians, and	12
The Challenge and Opportunity to Rationally Design Safer Commercial Chemicals	12
Special Issue on Tobacco: Chemistry, Mechanisms, Biomarkers and Disease Prevention	12
Chlorobenzoquinones Aggravate RSL3-Induced Ferroptosis in ROS-Dependent Manner	12
High-Field Asymmetric Waveform Ion Mobility Spectrometry Analysis of Carcinogenic Aromatic Amines in Tobacco Smoke with an Orbitrap Tribrid Mass Spectrometer	12
Pyrroloquinoline Quinone Chemistry, Biology, and Biosynthesis	12
Machine Learning Models for Predicting Cytotoxicity of Nanomaterials	12
Inhibitory Effects of Alkaloids on OATP1B1 In Vitro and In Vivo: Prediction for Food/Herb–Drug Interactions and Hepatoprotective Effects Based on Structure–Activity Relationships	12
Nucleophilic Addition of Thiols to Methacrylates for Biomedical Applications Revisited	12
Increased Levels of the Acrolein Metabolite 3-Hydroxypropyl Mercapturic Acid in the Urine of e-Cigarette Users	12
Long Noncoding RNA MIAT Modulates Chronic Retinal Ischemia-Reperfusion Injury in Mice via the microRNA-203-3p/SNAI2 Axis	12
Phthalate Exposure and Coronary Heart Disease: Possible Implications of Oxidative Stress and Altered miRNA Expression	12

Correction to “Oxymatrine Inhibits Liver Cancer Progression by Regulating SIRT1/YY1/GPX4 Axis-Mediated Ferroptosis”	12
New Insights into the Phototoxicity of Anthracene-Based Chromophores: The Chloride Salt Effect	12
Multiplatform Metabolomics to Understand the Imidacloprid-Induced Toxicity in Drosophila	12
Effects of E-Cigarette Flavor Enhancing Capsules on Inhalable Aerosols	12
Impact of Dietary Practices on DNA Adduct Formation by Aristolochic Acid I in Mice: Drinking Alkaline Water as a Risk Mitigation Strategy	11
Berberine Inhibits KLF4 Promoter Methylation and Ferroptosis to Ameliorate Diabetic Nephropathy in Mice	11
Comparative Study of Molecular Descriptors and AI-Based Embeddings for Toxicity Prediction	11
Identification of the Major Product of Guanine Oxidation in DNA by Ozone	11
Isotope Labeling Mass Spectrometry to Quantify Endogenous and Exogenous DNA Adducts and Metabolites of 1,3-Butadiene In Vivo	11
Carbonyls and Aerosol Mass Generation from Vaping Nicotine Salt Solutions Using Fourth- and Third-Generation E-Cigarette Devices: Effects of Coil Resistance, Coil Age, and Coil Metal Material	11
Novel Dual PPAR δ/γ Partial Agonist Induces Hepatic Lipid Accumulation through Direct Binding and Inhibition of AKT1 Phosphorylation, Mediating CD36 Upregulation	11
Leveraging Consensus Docking Approaches for Human Mitochondrial Complexes I and III	11
Chemical Exposures and Impact on Health	11
Ultrafast Reaction of the Drug Hydralazine with Apurinic/Apyrimidinic Sites in DNA Gives Rise to a Stable Triazolo[3,4-a]phthalazine Adduct	11
Prediction of Internal Exposures after Virtual Oral Doses of Disparate Chemicals in Rats and Humans Using Simplified Physiologically Based Pharmacokinetic Models with In Silico-Generated Input	11
Human CYP2C19 Substrate and Inhibitor Characterization of Organophosphate Pesticides	11
Antioxidant Activity and Skin Sensitization of Eugenol and Isoeugenol: Two Sides of the Same Coin?	11
Enantiomeric Fractions Reveal Differences in the Atropselective Disposition of 2,2′,3,5′,6-Pentachlorobiphenyl (PCB 95) in Wildtype, Cyp2abfgs-Null, and CYP2A6-Humanized Mice	11
Call for Papers: Special Issue on Nucleic Acid Modifications	11
Pesticides Inhibit Retinoic Acid Catabolism in PLHC-1 and ZFL Fish Hepatic Cell Lines	10
Issue Publication Information	10
Evidence for the Metabolic Activation of Deferasirox In Vitro and In Vivo	10
Evaluation of Six Aromatic Amines in the Mainstream Smoke of Commercial Cigars	10
Inhibition of Nicotine Metabolism by Cannabidiol (CBD) and 7-Hydroxycannabidiol (7-OH-CBD)	10
Chlorpyrifos Oxon Activates Glutamate and Lysine for Protein Cross-linking	10
Machine Learning for Toxicity Prediction Using Chemical Structures: Pillars for Success in the Real World	10
Natural Product Baohuoside I Impairs the Stability and Membrane Location of MRP2 Reciprocally Regulated by SUMOylation and Ubiquitination in Hepatocytes	10
Issue Publication Information	10
Ambient Fine Particulate Matter and Cancer: Current Evidence and Future Perspectives	10
Combining Molecular Docking and Pharmacophore Models Predicts Ligand Binding of Endocrine-Disrupting Chemicals to Nuclear Receptors	10
Assessment of the Exposure to Tobacco-Specific Nitrosamines and Minor Tobacco Alkaloids in Users of Various Tobacco/Nicotine Products	10
The Human Glyoxalase Gene Family in Health and Disease	10
Is Baikiain in Tara Flour a Causative Agent for the Adverse Events Associated with the Recalled Frozen French Lentil & Leek Crumbles Food Product? - A Working Hypothesis	10
Polyamine Adducts with AP Sites: Interaction with DNA Polymerases and AP Endonucleases	10
8-OxodGuo and Fapy•dG Mutagenicity in Escherichia coli Increases Significantly when They Are Part of a Tandem Lesion with 5-Formyl-2′-deoxyuridine	10
Searching for LINCS to Stress: Using Text Mining to Automate Reference Chemical Curation	10
Issue Publication Information	10
Review of the Protective Effects of Selenium against T-2 Toxin-Induced Toxicity	10
MlrA, an Essential Enzyme for Microcystins and Nodularin on First Step Biodegradation in Microcystin-Degrading Bacteria	10
Synergistic Interaction of Polycyclic Aromatic Hydrocarbons, Phthalate Esters, or Phenol on DNA Adduct Formation by Aristolochic Acid I: Insights into the Etiology of Balkan Endemic Nephropathy	9
Potential Role of Heterocyclic Aromatic Amines in Neurodegeneration	9
Introducing the Inaugural Early Career Board for Chemical Research in Toxicology	9
Ratiometric Fluorescent Probe for the Detection of Nanomolar Phosgene in Solution and Gaseous Phase: Advancing Crime Detection Applications	9
Nature-Derived Epoxy Resin Monomers with Reduced Sensitizing Capacity─Isosorbide-Based Bis-Epoxides	9
Conformation-Dependent Lesion Bypass and Mutagenicity of Bulky 2-Acetylaminofluorene-Guanine DNA Adduct in Epigenetically Relevant Sequence Contexts	9
Conformation and Pairing Properties of anO⁶-Methyl-2′-deoxyguanosine-Directed Benzimidazole Nucleoside Analog in Duplex DNA	9
Free Radicals in Cannabis Smoke	9
Advances on the Influence of Methylmercury Exposure during Neurodevelopment	9
Mixtures-Inclusive In Silico Models of Ocular Toxicity Based on United States and International Hazard Categories	9
Influence of Nitrite on Formation of Tobacco-Specific Nitrosamines in Electronic Cigarette Liquids and Aerosols	9
Quantification of Flavors, Volatile Organic Compounds, Tobacco Markers, and Tobacco-Specific Nitrosamines in Heated Tobacco Products and Their Mainstream Aerosol	9
Oxidation of Naringenin, Apigenin, and Genistein by Human Family 1 Cytochrome P450 Enzymes and Comparison of Interaction of Apigenin with Human P450 1B1.1 and Scutellaria P450 82D.1	9
Issue Publication Information	9
Dried Matrix Spots: An Underutilized and Unexplored Technology in India	9
Driving to a Better Understanding of Acyl Glucuronide Transformations Using NMR and Molecular Modeling	9
Improving Volatile Organic Compound Exposure Assessment Using Biomonitoring by Relating Exposure Biomarker Levels in Blood and Urine	9
Nuclear SUMOylation and Proteotoxic Stress Responses to Metals with Different Ligand Preferences	9
Migration of Soluble Polymers in Human Saliva during Swabbing Characterized by Direct Electrospray Ionization Mass Spectrometry	9
Data Exploration for Target Predictions Using Proprietary and Publicly Available Data Sets	9
Metabolic Characterization of Sarin, Cyclosarin, and Novichoks (A-230, A-232) in Human Liver Microsomes	9
Identification of Metoprolol Tartrate-Derived Reactive Metabolites Possibly Correlated with Its Cytotoxicity	9
Carbonyl Emissions and Heating Temperatures across 75 Nominally Identical Electronic Nicotine Delivery System Products: Do Manufacturing Variations Drive Pulmonary Toxicant Exposure?	9
Issue Editorial Masthead	9
A Membrane Biophysics Perspective on the Mechanism of Alcohol Toxicity	9
Role of Human Aldo-Keto Reductases and Nuclear Factor Erythroid 2-Related Factor 2 in the Metabolic Activation of 1,8-Dinitropyrene and Its Metabolite 1-Amino-8-nitropyrene via Nitroreduction in Human	9
High-Throughput Screening of ToxCast PFAS Chemical Library for Potential Inhibitors of the Human Sodium Iodide Symporter	8
Advances in Our Understanding of the Interaction of Drugs with T-cells: Implications for the Discovery of Biomarkers in Severe Cutaneous Drug Reactions	8
Issue Editorial Masthead	8
Untargeted DNA Adductomics Identifies Aristolochic Acid III as a Potent DNA-Damaging Agent among 11 Substituted Aromatic Genotoxicants in the Rat Urinary System	8
A Novel Inhibitor of Poly(ADP-Ribose) Polymerase-1 Inhibits Proliferation of a BRCA-Deficient Breast Cancer Cell Line *via* the DNA Damage–Activated cGAS–STING	8
Effects of N7-Alkylguanine Conformation and Metal Cofactors on the Translesion Synthesis by Human DNA Polymerase η	8
Identification of Specific Hemoglobin Adduct Patterns in Users of Different Tobacco/nicotine Products by Nontargeted GC–MS/MS Analysis	8
The Potential Contribution of Hexavalent Chromium to the Carcinogenicity of Chrysotile Asbestos	8
A Virtual Issue of Chemical Research in Toxicology in Celebration of the International Day of Women and Girls in Science	8
Interview with Dr. Wei Yang, 2022 Keynote Speaker, American Chemical Society Division of Chemical Toxicology	8
Quantum Chemical Evaluation and QSAR Modeling of N-Nitrosamine Carcinogenicity	8
Network Pharmacology Combined with Metabolomics Approach to Investigate the Toxicity Mechanism of Paclobutrazol	8
Halogen Atoms in Bisphenol A Derivatives Enhance the Inhibitory Potency against Human and Rat Placental 3β-Hydroxysteroid Dehydrogenases	8
Urinary Profile of Alkylated DNA Adducts and DNA Oxidative Damage in Sulfur Mustard-Exposed Rats Revealed by Mass Spectrometry Quantification	8
Formation of DHP-DNA Adducts from Rat Liver Microsomal Metabolism of 1,2-Unsaturated Pyrrolizidine Alkaloid-Containing Plant Extracts and Dietary Supplements	8
MetSim: Integrated Programmatic Access and Pathway Management for Xenobiotic Metabolism Simulators	8
Toxic Effects of Cobalt on Erythroid Progenitor Cells	8
Evaluating the Toxicity of Electronic Cigarette Aerosols for Firsthand and Secondhand Exposure Under Different Device Operating Conditions	8
Positive Ion Tandem Mass Spectrometry Offers Enhanced Structural Insights for the Discovery of Mercapturic Acids	7
A Reversible Mechanochromic AIEgen Based on Triphenylamine for the Selective Detection of Vitamin B2 (Riboflavin) in Aqueous Media and Histotoxicity	7
Active Binding Modes of Caffeine with Cytochrome P450 1A2 Determine Its Metabolite Profiles	7
Molecular Insights into Propofol’s Neurotoxic Effects: Targeting the HTR1A/cAMP Signaling Pathway	7
Issue Publication Information	7
Development of Comprehensive Ultraperformance Liquid Chromatography–High-Resolution Mass Spectrometry Assays to Quantitate Cisplatin-Induced DNA–DNA Cross-Links	7
Relationships between the Structure and Severe Drug-Induced Liver Injury for Low, Medium, and High Doses of Drugs	7
Replication Studies of Alkyl Phosphotriester Lesions in Human Cells	7
Levels of Urinary Mercapturic Acids of Acrolein, Methacrolein, Crotonaldehyde, and Methyl Vinyl Ketone in Relationship to Chronic Obstructive Pulmonary Disease in Cigarette Smokers of the Subpopulatio	7
Issue Publication Information	7
Automating Predictive Toxicology Using ComptoxAI	7
Effects of Heavy Metal Co-Exposure on the formation of DNA Adducts from Aristolochic Acid I: Implications for Balkan Endemic Nephropathy Development	7