Chemical Research in Toxicology

Article	Citations
The Tox21 10K Compound Library: Collaborative Chemistry Advancing Toxicology	151
Exposure of Human Lung Cells to Polystyrene Microplastics Significantly Retards Cell Proliferation and Triggers Morphological Changes	122
Toxicity of Carbon Nanotubes: Molecular Mechanisms, Signaling Cascades, and Remedies in Biomedical Applications	66
Impact of e-Liquid Composition, Coil Temperature, and Puff Topography on the Aerosol Chemistry of Electronic Cigarettes	63
Review on Metal-Based Nanoparticles: Role of Reactive Oxygen Species in Renal Toxicity	57
GLORYx: Prediction of the Metabolites Resulting from Phase 1 and Phase 2 Biotransformations of Xenobiotics	54
Benzophenone Accumulates over Time from the Degradation of Octocrylene in Commercial Sunscreen Products	53
Machine Learning in Predictive Toxicology: Recent Applications and Future Directions for Classification Models	53
Mitochondrial DNA Damage: Prevalence, Biological Consequence, and Emerging Pathways	49
Nuclear and Cytoplasmic Functions of Vitamin C	46
Using Rotenone to Model Parkinson’s Disease in Mice: A Review of the Role of Pharmacokinetics	45
Advances in Smoking Related In Vitro Inhalation Toxicology: A Perspective Case of Challenges and Opportunities from Progresses in Lung-on-Chip Technologies	44
Methylglyoxal and Its Adducts: Induction, Repair, and Association with Disease	41
DeepDILI: Deep Learning-Powered Drug-Induced Liver Injury Prediction Using Model-Level Representation	41
Exposure to Aluminum, Cadmium, and Mercury and Autism Spectrum Disorder in Children: A Systematic Review and Meta-Analysis	40
Prediction of the Blood–Brain Barrier (BBB) Permeability of Chemicals Based on Machine-Learning and Ensemble Methods	39
A Critical Review of Polychlorinated Biphenyls Metabolism, Metabolites, and Their Correlation with Oxidative Stress	39
Characterizing the Chemical Landscape in Commercial E-Cigarette Liquids and Aerosols by Liquid Chromatography–High-Resolution Mass Spectrometry	39
Evaluating the Cytotoxicity of Ti3C2 MXene to Neural Stem Cells	38
Practical and Science-Based Strategy for Establishing Acceptable Intakes for Drug Product N-Nitrosamine Impurities	37
Behavior Effects of Structurally Diverse Per- and Polyfluoroalkyl Substances in Zebrafish	37
Impact of the Physicochemical Features of TiO2 Nanoparticles on Their In Vitro Toxicity	35
Novel Δ8-Tetrahydrocannabinol Vaporizers Contain Unlabeled Adulterants, Unintended Byproducts of Chemical Synthesis, and Heavy Metals	35
A Mechanical Mechanism for Vitamin E Acetate in E-cigarette/Vaping-Associated Lung Injury	33
Microcystins: Biogenesis, Toxicity, Analysis, and Control	33

Development of a Web-Based Toolbox to Support Quantitative In-Vitro-to-In-Vivo Extrapolations (QIVIVE) within Nonanimal Testing Strategies	33
Trade-off Predictivity and Explainability for Machine-Learning Powered Predictive Toxicology: An in-Depth Investigation with Tox21 Data Sets	33
Pred-Skin: A Web Portal for Accurate Prediction of Human Skin Sensitizers	32
Advanced In Vitro Testing Strategies and Models of the Intestine for Nanosafety Research	32
Neurotransmission Targets of Per- and Polyfluoroalkyl Substance Neurotoxicity: Mechanisms and Potential Implications for Adverse Neurological Outcomes	31
Arsenic Exposure and Compromised Protein Quality Control	29
Cannabis Vaping: Existing and Emerging Modalities, Chemistry, and Pulmonary Toxicology	29
Hair Dye Ingredients and Potential Health Risks from Exposure to Hair Dyeing	29
Comparison of Cellular Morphological Descriptors and Molecular Fingerprints for the Prediction of Cytotoxicity- and Proliferation-Related Assays	29
Hormesis: A General Biological Principle	28
Graphene-Based Materials In Vitro Toxicity and Their Structure–Activity Relationships: A Systematic Literature Review	28
Induction of Protective Response Associated with Expressional Alterations in Neuronal G Protein-Coupled Receptors in Polystyrene Nanoparticle Exposed Caenorhabditis elegans	28
Chemical and Toxicological Characterization of Vaping Emission Products from Commonly Used Vape Juice Diluents	28
Metabolism and Toxicity of Fluorine Compounds	27
Ensemble Models Based on QuBiLS-MAS Features and Shallow Learning for the Prediction of Drug-Induced Liver Toxicity: Improving Deep Learning and Traditional Approaches	27
Physiologically Based Pharmacokinetic Models Predicting Renal and Hepatic Concentrations of Industrial Chemicals after Virtual Oral Doses in Rats	27
Free Radical Production and Characterization of Heat-Not-Burn Cigarettes in Comparison to Conventional and Electronic Cigarettes	25
Toxicological Responses of α-Pinene-Derived Secondary Organic Aerosol and Its Molecular Tracers in Human Lung Cell Lines	25
Thermodynamic Parameters at Bio–Nano Interface and Nanomaterial Toxicity: A Case Study on BSA Interaction with ZnO, SiO2, and TiO2	25
Interactions of Perfluorooctanesulfonate and 6:2 Chlorinated Polyfluorinated Ether Sulfonate with Human Serum Albumin: A Comparative Study	24
On Some Novel Similarity-Based Functions Used in the ML-Based q-RASAR Approach for Efficient Quantitative Predictions of Selected Toxicity End Points	24
What Makes a Potent Nitrosamine? Statistical Validation of Expert-Derived Structure–Activity Relationships	24
In Silico Prediction of Input Parameters for Simplified Physiologically Based Pharmacokinetic Models for Estimating Plasma, Liver, and Kidney Exposures in Rats after Oral Doses of 246 Disparate	24
Critical Membrane Concentration and Mass-Balance Model to Identify Baseline Cytotoxicity of Hydrophobic and Ionizable Organic Chemicals in Mammalian Cell Lines	24
An Evaluation of the Occupational Health Hazards of Peptide Couplers	24
In Silico Models to Predict the Perturbation of Molecular Initiating Events Related to Thyroid Hormone Homeostasis	24
Machine Learning Models for Predicting Cytotoxicity of Nanomaterials	22
Nonclinical Evaluation of Antibacterial Oxazolidinones Contezolid and Contezolid Acefosamil with Low Serotonergic Neurotoxicity	22
Integrated Proteomics and Metabolomics Reveal the Mechanism of Nephrotoxicity Induced by Triptolide	22
EGFR Inhibitor Gefitinib Induces Cardiotoxicity through the Modulation of Cardiac PTEN/Akt/FoxO3a Pathway and Reactive Metabolites Formation: In Vivo and in Vitro Rat Studies	22
Graphene Family Nanomaterials in Ocular Applications: Physicochemical Properties and Toxicity	22
Nitroreduction: A Critical Metabolic Pathway for Drugs, Environmental Pollutants, and Explosives	21
Redox Activity of Flavonoids: Impact on Human Health, Therapeutics, and Chemical Safety	21
Role of Hydrazine-Related Chemicals in Cancer and Neurodegenerative Disease	21
High-Throughput Screening to Identify Chemical Cardiotoxic Potential	21
Prediction-Inspired Intelligent Training for the Development of Classification Read-across Structure–Activity Relationship (c-RASAR) Models for Organic Skin Sensitizers: Assessment of Classification E	21
Quantitative Liquid Chromatography–Nanoelectrospray Ionization–High-Resolution Tandem Mass Spectrometry Analysis of Acrolein-DNA Adducts and Etheno-DNA Adducts in Oral Cells from Cigarette Smokers and	21
Unexpected Complexity in the Products Arising from NaOH-, Heat-, Amine-, and Glycosylase-Induced Strand Cleavage at an Abasic Site in DNA	20
Deep Graph Learning with Property Augmentation for Predicting Drug-Induced Liver Injury	20
New Perspectives on Drug-Induced Liver Injury Risk Assessment of Acyl Glucuronides	20
Looking for Post-Mortem Metabolomic Standardization: Waiting for Godot—The Importance of Post-Mortem Interval in Forensic Metabolomics	19
Toxicity of Water- and Organic-Soluble Wood Tar Fractions from Biomass Burning in Lung Epithelial Cells	19
Disposable Puff Bar Electronic Cigarettes: Chemical Composition and Toxicity of E-liquids and a Synthetic Coolant	18
Volatile Organic Compounds in Mainstream Smoke of Sixty Domestic Little Cigar Products	18
Determination of Aristolochic Acids in Vegetables: Nephrotoxic and Carcinogenic Environmental Pollutants Contaminating a Broad Swath of the Food Supply and Driving Incidence of Balkan Endemic Nephropa	18
Cardiotoxicity Hazard and Risk Characterization of ToxCast Chemicals Using Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes from Multiple Donors	18
ATF3 Modulates the Resistance of Breast Cancer Cells to Tamoxifen through an N6-Methyladenosine-Based Epitranscriptomic Mechanism	17
HIF1, HSF1, and NRF2: Oxidant-Responsive Trio Raising Cellular Defenses and Engaging Immune System	17
Verification of Exposure to Novichok Nerve Agents Utilizing a Semitargeted Human Butyrylcholinesterase Nonapeptide Assay	17
Potential Role of Heterocyclic Aromatic Amines in Neurodegeneration	16

High-Resolution Metabolomic Assessment of Pesticide Exposure in Central Valley, California	16
Production of a Urinary Selenium Metabolite, Trimethylselenonium, by Thiopurine S-Methyltransferase and Indolethylamine N-Methyltransferase	16
Targeting Human Islet Amyloid Polypeptide Aggregation and Toxicity in Type 2 Diabetes: An Overview of Peptide-Based Inhibitors	16
Electronic Cigarette Refill Fluids Sold Worldwide: Flavor Chemical Composition, Toxicity, and Hazard Analysis	16
Exploring Flow Cytometry-Based Micronucleus Scoring for Reliable Nanomaterial Genotoxicity Assessment	16
Detection and Discrimination of DNA Adducts Differing in Size, Regiochemistry, and Functional Group by Nanopore Sequencing	16
Mechanistic Insights into the Role of Iron, Copper, and Carbonaceous Component on the Oxidative Potential of Ultrafine Particulate Matter	16
Comparison of Genotoxicity and Cytotoxicity of Polyvinyl Chloride and Poly(methyl methacrylate) Nanoparticles on Normal Human Lung Cell Lines	16
Hot Wires and Film Boiling: Another Look at Carbonyl Formation in Electronic Cigarettes	16
Determination of (R)-(+)- and (S)-(−)-Nicotine Chirality in Puff Bar E-Liquids by 1H NMR Spectroscopy, Polarimetry, and Gas Chromatography–Mass Spectrometry	15
The Antiviral Drug Tilorone Is a Potent and Selective Inhibitor of Acetylcholinesterase	15
Polychlorinated Biphenyl Quinone Promotes Atherosclerosis through Lipid Accumulation and Endoplasmic Reticulum Stress via CD36	15
Flavor-Toxicant Correlation in E-cigarettes: A Meta-Analysis	15
Density Functional Theory in the Prediction of Mutagenicity: A Perspective	15
Butyl Benzyl Phthalate Promotes Adipogenesis in 3T3-L1 Cells via the miRNA-34a-5p Signaling Pathway in the Absence of Exogenous Adipogenic Stimuli	15
Do Similar Structures Have Similar No Observed Adverse Effect Level (NOAEL) Values? Exploring Chemoinformatics Approaches for Estimating NOAEL Bounds and Uncertainties	15
Ozone-Induced DNA Damage: A Pandora’s Box of Oxidatively Modified DNA Bases	15
Tryptophan Pathway-Targeted Metabolomics Study on the Mechanism and Intervention of Cisplatin-Induced Acute Kidney Injury in Rats	15
Exploring the Potential of ToxCast Data in Supporting Read-Across for Evaluation of Food Chemical Safety	14
Metabolic Activation of Atomoxetine Mediated by Cytochrome P450 2D6	14
Systematic Identification of Molecular Targets and Pathways Related to Human Organ Level Toxicity	14
Assessing Vesicular Monoamine Transport and Toxicity Using Fluorescent False Neurotransmitters	14
Adsorption of Horseradish Peroxidase on Metallic Nanoparticles: Effects on Reactive Oxygen Species Detection Using 2′,7′-Dichlorofluorescin Diacetate	14
Vaped Humectants in E-Cigarettes Are a Source of Phenols	14
Liver Injury Caused by Green Tea Extract in PD-1–/– Mice: An Impaired Immune Tolerance Model for Idiosyncratic Drug-Induced Liver Injury	14
Reaction of Cyanide with Hg0-Contaminated Gold Mining Tailings Produces Soluble Mercuric Cyanide Complexes	14
Integrated In Silico Models for the Prediction of No-Observed-(Adverse)-Effect Levels and Lowest-Observed-(Adverse)-Effect Levels in Rats for Sub-chronic Repeated-Dose Toxicity	14
Tobacco-Specific Nitrosamines in the Tobacco and Mainstream Smoke of Commercial Little Cigars	14
Human Metabolism and Urinary Excretion Kinetics of Nonylphenol in Three Volunteers after a Single Oral Dose	14
Reactive Metabolites from Thiazole-Containing Drugs: Quantum Chemical Insights into Biotransformation and Toxicity	14
Metabolic Pattern of Hepatotoxic Pyrrolizidine Alkaloids in Liver Cells	14
Mutagenic and Cancer Risk Estimation of Particulate Bound Polycyclic Aromatic Hydrocarbons from the Emission of Different Biomass Fuels	14
Drug Safety Data Curation and Modeling in ChEMBL: Boxed Warnings and Withdrawn Drugs	14
Mechanistic Insights into the Cytotoxicity of Graphene Oxide Derivatives in Mammalian Cells	14
Exposure Assessment of Toxicologically Relevant Volatile Organic Compounds Emitted from Polymer-Based Costume Masks	13
Structure Activity Relationship for Fumonisin Phytotoxicity	13
Enhanced Disrupting Effect of Benzophenone-1 Chlorination Byproducts to the Androgen Receptor: Cell-Based Assays and Gaussian Accelerated Molecular Dynamics Simulations	13
Advances on the Influence of Methylmercury Exposure during Neurodevelopment	13
Protective Role of Glutathione against Peroxynitrite-Mediated DNA Damage During Acute Inflammation	13
Tolvaptan- and Tolvaptan-Metabolite-Responsive T Cells in Patients with Drug-Induced Liver Injury	13
Effects of E-Cigarette Aerosols with Varying Levels of Nicotine on Biomarkers of Oxidative Stress and Inflammation in Mice	13
Electronic Cigarette Solvents, JUUL E-Liquids, and Biomarkers of Exposure: In Vivo Evidence for Acrolein and Glycidol in E-Cig-Derived Aerosols	13
Teneligliptin Promotes Bile Acid Synthesis and Attenuates Lipid Accumulation in Obese Mice by Targeting the KLF15-Fgf15 Pathway	13
Assessment of the Exposure to Tobacco-Specific Nitrosamines and Minor Tobacco Alkaloids in Users of Various Tobacco/Nicotine Products	13
Predicting Chemical-Induced Liver Toxicity Using High-Content Imaging Phenotypes and Chemical Descriptors: A Random Forest Approach	13
Predicted AS3MT Proteins Methylate Arsenic and Support Two Major Phylogenetic AS3MT Groups	13
Characterizing Adduct Formation of Electrophilic Skin Allergens with Human Serum Albumin and Hemoglobin	13
Diet and Obesity-Induced Methylglyoxal Production and Links to Metabolic Disease	13
Epigenomic, Transcriptomic, and Protective Effect of Carotenoid Fucoxanthin in High Glucose-Induced Oxidative Stress in Mes13 Kidney Mesangial Cells	13
Carrier Solvents of Electronic Nicotine Delivery Systems Alter Pulmonary Surfactant	13
Investigation of the Interaction between Human Serum Albumin and Branched Short-Chain Perfluoroalkyl Compounds	12
COVID-19, Air Pollution, and Racial Inequity: Connecting the Dots	12
Biological Impacts of Reduced Graphene Oxide Affected by Protein Corona Formation	12
Systematic Analysis of Protein Targets Associated with Adverse Events of Drugs from Clinical Trials and Postmarketing Reports	12
Mechanism-Based Inactivation of Cytochrome P450 Enzymes: Computational Insights	12
In Silico Prediction of Human and Rat Liver Microsomal Stability via Machine Learning Methods	12
Evaluation of Per- and Polyfluoroalkyl Substances (PFAS) In Vitro Toxicity Testing for Developmental Neurotoxicity	12
Triterpenoids as Reactive Oxygen Species Modulators of Cell Fate	12
In Silico Prediction of CYP2C8 Inhibition with Machine-Learning Methods	12
Vaping Cannabinoid Acetates Leads to Ketene Formation	12
Strategies to Mitigate the Bioactivation of Aryl Amines	12
Neuroprotective Effects of Carnitine and Its Potential Application to Ameliorate Neurotoxicity	12
Impact of Atomizer Age and Flavor on In Vitro Toxicity of Aerosols from a Third-Generation Electronic Cigarette against Human Oral Cells	12
Critical Choices in Predicting Stone Wool Biodurability: Lysosomal Fluid Compositions and Binder Effects	12
Mass Spectrometry Analysis of DNA and Protein Adducts as Biomarkers in Human Exposure to Cigarette Smoking: Acrolein as an Example	12
Post-Mortem Metabolomics: A Novel Approach in Clinical Biomarker Discovery and a Potential Tool in Death Investigations	12
PARP1 Is Required for ATM-Mediated p53 Activation and p53-Mediated Gene Expression after Ionizing Radiation	12
DNA Damage and Oxidative Stress of Tobacco Smoke Condensate in Human Bladder Epithelial Cells	12
Evaluation of a Three-Dimensional Primary Human Hepatocyte Spheroid Model: Adoption and Industrialization for the Enhanced Detection of Drug-Induced Liver Injury	12
Mapping Chemical Respiratory Sensitization: How Useful Are Our Current Computational Tools?	12
Liquid Chromatography-Nanoelectrospray Ionization-High-Resolution Tandem Mass Spectrometry Analysis of Apurinic/Apyrimidinic Sites in Oral Cell DNA of Cigarette Smokers, e-Cigarette Users, and Nonsmok	12
Systems Toxicology Approach for Testing Chemical Cardiotoxicity in Larval Zebrafish	12
Formation of Redox-Active Duroquinone from Vaping of Vitamin E Acetate Contributes to Oxidative Lung Injury	12
1,2-Naphthoquinone as a Poison of Human Type II Topoisomerases	11
Modeling the Bioactivation and Subsequent Reactivity of Drugs	11
Exposure to an Environmental Mixture of Polycyclic Aromatic Hydrocarbons Induces Hepatic Cytochrome P450 Enzymes in Mice	11
Effects of Bisphenol A and Bisphenol S Exposure at Low Doses on the Metabolome of Adolescent Male Sprague–Dawley Rats	11
Formation Mechanism and Toxicological Significance of Biogenic Mercury Selenide Nanoparticles in Human Hepatoma HepG2 Cells	11
Introduction to Special Issue: Computational Toxicology	11
Mass Spectrometric Profiling of Neuropeptides in Response to Copper Toxicity via Isobaric Tagging	11

In Vivo Metabolism of Aristolochic Acid I and II in Rats Is Influenced by Their Coexposure	11
Oral Dosing of Dihydromethysticin Ahead of Tobacco Carcinogen NNK Effectively Prevents Lung Tumorigenesis in A/J Mice	11
Quantitation of Protein Adducts of Aristolochic Acid I by Liquid Chromatography–Tandem Mass Spectrometry: A Novel Method for Biomonitoring Aristolochic Acid Exposure	11
Skin Doctor CP: Conformal Prediction of the Skin Sensitization Potential of Small Organic Molecules	11
Green Toxicology: Connecting Green Chemistry and Modern Toxicology	11
Mechanism-Based Inactivation of Cytochrome P450 3A4 and 3A5 by the Fibroblast Growth Factor Receptor Inhibitor Erdafitinib	11
The Human Glyoxalase Gene Family in Health and Disease	11
Cytochrome P450 Mediated Bioactivation of Rutaevin, a Bioactive and Potentially Hepatotoxic Component of Evodia Rutaecarpa	11
Emerging Chemicals of Health Concern in Electronic Nicotine Delivery Systems	11
Benzyl Butyl Phthalate Induced Early lncRNA H19 Regulation in C3H10T1/2 Stem Cell Line	11
Nonclinical Toxicological Studies of Brazilian Red Propolis and Its Primary Botanical Source Dalbergia ecastaphyllum	11
Characterization and Quantification of Oxidized High Mobility Group Box 1 Proteoforms Secreted from Hepatocytes by Toxic Levels of Acetaminophen	11
Quantitative Structure–Activity Relationship (QSAR) Model for the Severity Prediction of Drug-Induced Rhabdomyolysis by Using Random Forest	11
In Silico Assessment of Acute Oral Toxicity for Mixtures	11
Hepatotoxicity of Cadmium Telluride Quantum Dots Induced by Mitochondrial Dysfunction	11
Inhibition of Nicotine Metabolism by Cannabidiol (CBD) and 7-Hydroxycannabidiol (7-OH-CBD)	11
Plasma Protein Binding Evaluations of Per- and Polyfluoroalkyl Substances for Category-Based Toxicokinetic Assessment	11
Autophagy Plays a Protective Role in Sodium Hydrosulfide-Induced Acute Lung Injury by Attenuating Oxidative Stress and Inflammation in Rats	11
Metabolites of Tobacco- and E-Cigarette-Related Nitrosamines Can Drive Cu2+-Mediated DNA Oxidation	11
Pyrroloquinoline Quinone Chemistry, Biology, and Biosynthesis	11
Interstrand Cross-Link Formation Involving Reaction of a Mispaired Cytosine Residue with an Abasic Site in Duplex DNA	10
Harnessing In Silico, In Vitro, and In Vivo Data to Understand the Toxicity Landscape of Polycyclic Aromatic Compounds (PACs)	10
Methylmercury Can Facilitate the Formation of Dehydroalanine in Selenoenzymes: Insight from DFT Molecular Modeling	10
Linking Coregulated Gene Modules with Polycyclic Aromatic Hydrocarbon-Related Cancer Risk in the 3D Human Bronchial Epithelium	10
Role of Citrus medica L. Fruits Extract in Combatting the Hematological and Hepatic Toxic Effects of Carbofuran	10
Metabolic Activation and Cytotoxicity of Labetalol Hydrochloride Mediated by Sulfotransferases	10
Effects of Standardized Medicinal Plant Extracts on Drug Metabolism Mediated by CYP3A4 and CYP2D6 Enzymes	10
Unexpected Observations: Probiotic Administration Greatly Aggravates the Reproductive Toxicity of Perfluorobutanesulfonate in Zebrafish	10
Identification of an N′-Nitrosonornicotine-Specific Deoxyadenosine Adduct in Rat Liver and Lung DNA	10
Polystyrene Nanoplastics Induce Neutrophil Extracellular Traps in Mice Neutrophils	10
Post-Mortem Changes of Methomyl in Blood with Hemoglobin	10
Predicting DNA-Reactivity of N-Nitrosamines: A Quantum Chemical Approach	10
Effects of Gut Microbiome on Carcinogenic DNA Damage	10
Biomarkers of DNA Oxidation Products: Links to Exposure and Disease in Public Health Studies	10
Dose-Dependent Molecular Responses of Labeo rohita to Triphenyl Phosphate	10
Genetically Encoded Fluorescent Redox Indicators for Unveiling Redox Signaling and Oxidative Toxicity	10
Is It Realistic to Propose Determination of a Lifetime Internal Exposome?	10
Effects of GSTT1 Genotype on the Detoxification of 1,3-Butadiene Derived Diepoxide and Formation of Promutagenic DNA–DNA Cross-Links in Human Hapmap Cell Lines	10
Thinking Outside the Cage: A New Hypothesis That Accounts for Variable Yields of Radicals from the Reaction of CO2 with ONOO–	10
Profiling How the Gut Microbiome Modulates Host Xenobiotic Metabolism in Response to Benzo[a]pyrene and 1-Nitropyrene Exposure	10
Amiodarone, Unlike Dronedarone, Activates Inflammasomes via Its Reactive Metabolites: Implications for Amiodarone Adverse Reactions	10
Biological Basis for Threshold Responses to Methylating Agents	10
Targeting Chloride Ion Channels: New Insights into the Mechanism of Action of the Marine Toxin Azaspiracid	10
Use of Cause-and-Effect Analysis to Optimize the Reliability of In Vitro Inhalation Toxicity Measurements Using an Air–Liquid Interface	10
Probing the Hidden Role of Mitochondrial DNA Damage and Dysfunction in the Etiology of Aristolochic Acid Nephropathy	10
Investigation of 2′-Deoxyadenosine-Derived Adducts Specifically Formed in Rat Liver and Lung DNA by N′-Nitrosonornicotine Metabolism	9
Biomonitoring of Ambient Outdoor Air Pollutant Exposure in Humans Using Targeted Serum Albumin Adductomics	9
Analysis of Nicotine and Non-nicotine Tobacco Constituents in Aqueous Smoke/Aerosol Extracts by UHPLC and Ultraperformance Convergence Chromatography–Tandem Mass Spectrometry	9
Polybrominated Diphenyl Ether Quinone Exposure Induces Atherosclerosis Progression via CD36-Mediated Lipid Accumulation, NLRP3 Inflammasome Activation, and Pyroptosis	9
Development of a Battery of In Silico Prediction Tools for Drug-Induced Liver Injury from the Vantage Point of Translational Safety Assessment	9
Antagonism of GPR4 with NE 52-QQ57 and the Suppression of AGE-Induced Degradation of Type II Collagen in Human Chondrocytes	9
In Vivo Identification of Adducts from the New Hypoxia-Activated Prodrug CP-506 Using DNA Adductomics	9
Effects of Charged Oxime Reactivators on the HK-2 Cell Line in Renal Toxicity Screening	9
Binimetinib Is a Potent Reversible and Time-Dependent Inhibitor of Cytochrome P450 1A2	9
Organophosphorus Pesticides Promote Protein Cross-Linking	9
Distinct Orchestration and Dynamic Processes on γ-H2AX and p-H3 for Two Major Types of Genotoxic Chemicals Revealed by Mass Spectrometry Analysis	9
Establishing Linkages Among DNA Damage, Mutagenesis, and Genetic Diseases	9
Energy Starvation in Daphnia magna from Exposure to a Lithium Cobalt Oxide Nanomaterial	9
Examining Metal Contents in Primary and Secondhand Aerosols Released by Electronic Cigarettes	9
Role of Protein Damage Inflicted by Dopamine Metabolites in Parkinson’s Disease: Evidence, Tools, and Outlook	9
The Effects of Polychlorinated Biphenyl Exposure During Adolescence on the Nervous System: A Comprehensive Review	9
Artificial Intelligence Meets Toxicology	9
Applications of CometChip for Environmental Health Studies	9
Uptake and Removal of Uranium by and from Human Teeth	9
Chronic Exposure to Climbazole Induces Oxidative Stress and Sex Hormone Imbalance in the Testes of Male Zebrafish	9
Chemical and Biochemical Aspects of Molecular Hydrogen in Treating Kawasaki Disease and COVID-19	9
An Updated In Silico Prediction Method for Volumes of Systemic Circulation of 323 Disparate Chemicals for Use in Physiologically Based Pharmacokinetic Models to Estimate Plasma and Tissue Conce	9
Cytochrome P450-Mediated Bioactivation: Implication for the Liver Injury Induced by Fraxinellone, A Bioactive Constituent from Dictamni Cortex	9
Quantifying Analogue Suitability for SAR-Based Read-Across Toxicological Assessment	9
Differential Cytotoxicity of Haloaromatic Disinfection Byproducts and Lead Co-exposures against Human Intestinal and Neuronal Cells	9
Experimental Exposure Assessment of Ionizable Organic Chemicals in In Vitro Cell-Based Bioassays	9
Maternal Sodium p-Perfluorous Nonenoxybenzene Sulfonate Exposure Disturbed Lipid Metabolism and Induced an Imbalance in Tyrosine Metabolism in the F1 Generation of Mice	9
Mass Spectrometric Quantitation of Apurinic/Apyrimidinic Sites in Tissue DNA of Rats Exposed to Tobacco-Specific Nitrosamines and in Lung and Leukocyte DNA of Cigarette Smokers and Nonsmokers	9
Phytochemicals in the Management of Arsenic Toxicity	9
Principal Metabolites in Extracts of Different Plants Responsible for Antibacterial Effects	9
A Gene Expression Biomarker Identifies Chemical Modulators of Estrogen Receptor α in an MCF-7 Microarray Compendium	9
In Vitro Glucuronidation of Caribbean Ciguatoxins in Fish: First Report of Conjugative Ciguatoxin Metabolites	9
Alternaria alternata Mycotoxins Activate the Aryl Hydrocarbon Receptor and Nrf2-ARE Pathway to Alter the Structure and Immune Response of Colon Epithelial Cells	8
UVB Drives Metabolic Rewiring and Epigenetic Reprograming and Protection by Sulforaphane in Human Skin Keratinocytes	8
Direct Alkylation of Deoxyguanosine by Azaserine Leads to O6-Carboxymethyldeoxyguanosine	8
Insights into the Molecular Mechanisms of Liuwei Dihuang Decoction via Network Pharmacology	8
Ecotoxicity Risk of Low-Dose Methylmercury Exposure to Caenorhabditis elegans: Multigenerational Toxicity and Population Discrepancy	8
Saagar–A New, Extensible Set of Molecular Substructures for QSAR/QSPR and Read-Across Predictions	8
New Associations between Drug-Induced Adverse Events in Animal Models and Humans Reveal Novel Candidate Safety Targets	8
Metabolic Profiles of Tetrabromobisphenol A in Humans Extrapolated from Humanized-Liver Mouse Data Using a Simplified Physiologically Based Pharmacokinetic Model	8
Gas Chromatography-Tandem Mass Spectrometry Verification of Sulfur Mustard Exposure in Humans through the Conversion of Protein Adducts to Free Sulfur Mustard	8
Analysis of Biomarkers of DNA Damage and Mutagenicity in Mice Exposed to Acrylonitrile	8
Novel Poly(ADP-ribose) Polymerase-1 Inhibitor DDHCB Inhibits Proliferation of BRCA Mutant Breast Cancer Cell In Vitro and In Vivo through a Synthetic Lethal Mechanism	8
Evidence for Polyamine, Biogenic Amine, and Amino Acid Adduction Resulting from Metabolic Activation of Diosbulbin B	8
Diclofenac Sodium Triggers p53-Dependent Apoptosis in Human Corneal Epithelial Cells via ROS-Mediated Crosstalk	8
Products Generated by Amine-Catalyzed Strand Cleavage at Apurinic/Apyrimidinic Sites in DNA: New Insights from a Biomimetic Nucleoside Model System	8
Identification of Formaldehyde-Induced DNA–RNA Cross-Links in the A/J Mouse Lung Tumorigenesis Model	8
Role of Particulate Matter from Afghanistan and Iraq in Deployment-Related Lung Disease	8
Cellular Interactions and Fatty Acid Transporter CD36-Mediated Uptake of Per- and Polyfluorinated Alkyl Substances (PFAS)	8
Chemistry, Pharmacology, and Toxicology of Monoisoamyl Dimercaptosuccinic Acid: A Chelating Agent for Chronic Metal Poisoning	8