Chemical Research in Toxicology

Papers
(The TQCC of Chemical Research in Toxicology is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)
ArticleCitations
Elevating Research and Careers in the Development of Safer Drugs through Artificial Intelligence89
Oxidative Deformylation of the Predominant DNA Lesion 5-Formyl-2′-deoxyuridine85
Capture of Electrophilic Quinones in the Extracellular Space: Evidence for a Phase Zero Reaction73
Recent Advances in DNA Lesion Mapping and Repair Mechanisms69
Electrochemical Simulation of the Oxidative Capsaicin Metabolism66
Predicting Liver-Related In Vitro Endpoints with Machine Learning to Support Early Detection of Drug-Induced Liver Injury56
Coumarin-Based Noncytotoxicity Fluorescent Dye for Tracking Actin Protein in In-Vivo Imaging53
Surfactant Coformulants in Glyphosate-Based Herbicides: Current Gaps, and Paths Forward in Human Biomonitoring52
Dissecting the Enantioselective Neurotoxicity of Isocarbophos: Chiral Insight from Cellular, Molecular, and Computational Investigations50
LA-ICP-MS and Immunohistochemical Staining with Lanthanide-Labeled Antibodies to Study the Uptake of CeO2 Nanoparticles by Macrophages in Tissue Sections49
A Weakly Supervised Deep Learning Framework for Whole Slide Classification to Facilitate Digital Pathology in Animal Study47
Advances in Metabolism and Metabolic Toxicology of Quinoxaline 1,4-Di-N-oxides47
Identification of an Epoxide Metabolite of Amitriptyline In Vitro and In Vivo42
Systematic Investigation of CYP3A4 Using Side-by-Side Comparisons of Apo, Active Site, and Allosteric-Bound States41
Issue Publication Information40
Issue Publication Information40
Issue Editorial Masthead39
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Protein Haptenation and Its Role in Allergy35
Mechanistic Insights into Toxicity of Titanium Dioxide Nanoparticles at the Micro- and Macro-levels34
In Vitro and In Vivo Analysis of Fentanyl and Fentalog Metabolites using Hyphenated Chromatographic Techniques: A Review33
Bioaccumulation and DNA Adduct Formation of Aristolactam I: Unmasking a Toxicological Mechanism in the Pathophysiology of Aristolochic Acid Nephropathy33
A Review on the Recent Applications of Deep Learning in Predictive Drug Toxicological Studies32
Application of Covalent Binding Body Burden in the HμREL Human Hepatocyte Coculture Model for Reactivity Risk Assessment of Metabolically Low Turnover Drugs31
Cellular Interactions and Fatty Acid Transporter CD36-Mediated Uptake of Per- and Polyfluorinated Alkyl Substances (PFAS)31
Alternaria alternata Mycotoxins Activate the Aryl Hydrocarbon Receptor and Nrf2-ARE Pathway to Alter the Structure and Immune Response of Colon Epithelial Cells30
Mass Spectrometry-Based Metabolic Profiling of Urinary Metabolites of N′-Nitrosonornicotine (NNN) in the Rat29
Nonclinical Safety Signals in PharmaPendium Improve the Predictability of Human Drug-Induced Liver Injury29
Leveraging Cell Painting Images to Expand the Applicability Domain and Actively Improve Deep Learning Quantitative Structure–Activity Relationship Models28
Potential Involvement of Sulfotransferase in the Mechanism of Lamotrigine-induced Skin Rash28
The Toxicity of Poly(acrylonitrile-styrene–butadiene) Microplastics toward Hyalella azteca Is Associated with Biofragmentation and Oxidative Stress28
Federated Learning in Computational Toxicology: An Industrial Perspective on the Effiris Hackathon27
Computational Prediction of Metabolic α-Carbon Hydroxylation Potential ofN-Nitrosamines: Overcoming Data Limitations for Carcinogenicity Assessment27
ZIM, a Norbornene Derived from 4-Aminoantipyrine, Induces DNA Damage and Cell Death but in Association Reduces the Effect of Commercial Chemotherapeutics26
Characterizing the Chemical Landscape in Commercial E-Cigarette Liquids and Aerosols by Liquid Chromatography–High-Resolution Mass Spectrometry26
2,2′,4,4′-Tetrabromodiphenyl Ether (PBDE 47) Selectively Stimulates Proatherogenic PPARγ Signatures in Human THP-1 Macrophages to Contribute to Foam Cell Formation26
Photosensitized Oxidation of Free and Peptide Tryptophan to N-Formylkynurenine25
Modeling the Toxicokinetics of Suspensions of Soluble Metallic Nanomaterials25
Prediction of Cytochrome P450 Substrates Using the Explainable Multitask Deep Learning Models24
Products Generated by Amine-Catalyzed Strand Cleavage at Apurinic/Apyrimidinic Sites in DNA: New Insights from a Biomimetic Nucleoside Model System24
Characterization of Teicoplanin-Specific T-Cells from Drug Naïve Donors Expressing HLA-A*32:0124
Response to ‘Comments on “Tobacco-Specific Nitrosamines in the Tobacco and Mainstream Smoke of Commercial Little Cigars”’ Letter to Editor23
Conditional Binding of Arsenic Trioxide (ATO) to Cysteine-Rich Zinc Finger Motifs within RBCC Domain of PML Protein23
LC–MS/MS Analysis of Reaction Products of Arginine/Methylarginines with Methylglyoxal/Glyoxal23
Structural Elucidation of Agrochemical Metabolic Transformation Products Based on Infrared Ion Spectroscopy to Improve In Silico Toxicity Assessment23
Quantum Mechanical Assessment of Nitrosamine Potency22
Assessing the Toxicity of Terpene- and Amino Acid-Based Natural Deep Eutectic Solvents22
HDAC6-Mediated NLRP3 Inflammasome Activation Is Involved in Nickel Nanoparticle-Induced Pulmonary Inflammation and Fibrosis21
Issue Editorial Masthead21
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Issue Editorial Masthead20
Advancing Drug Safety in Drug Development: Bridging Computational Predictions for Enhanced Toxicity Prediction20
Quantum-Mechanical Approach to Predicting the Carcinogenic Potency of N-Nitroso Impurities in Pharmaceuticals20
Issue Editorial Masthead20
Free Radicals in Little Cigar Mainstream Smoke and the Potential Influence of Flavoring Chemicals on Free Radical Production19
Simultaneous Quantification of Biomarkers for Bis-(2-chloroethyl) Sulfide and 1,2-Bis(2-chloroethylthio) Ethane Exposure in Human Urine at Trace Exposure Levels by Gas Chromatography Tandem Mass Spect19
Melatonin Vapes Contain Potential Contaminants and Alter the Human Bronchial Epithelial Transcriptome19
Zebrafish Larvae as a Predictive Model for the Risk of Chemical-Induced Cholestasis: Phenotypic Evaluation and Nomogram Formation19
Metals in Cannabis Vaporizer Aerosols: Sources, Possible Mechanisms, and Exposure Profiles19
Issue Editorial Masthead19
Nontargeted Analysis in Tobacco Research: Challenges and Opportunities19
Issue Editorial Masthead19
Acrylamide-Aggravated Liver Injury by Activating Endoplasmic Reticulum Stress in Female Mice with Diabetes19
Issue Publication Information19
Nucleophilic Thiol Proteins Bind Covalently to Abasic Sites in DNA18
Chemoproteomic Approach for Identifying Nuclear Arsenite-Binding Proteins18
Photo-oxidation and Photoreduction of Catechols by Chlorophyll Metabolites and Methylene Blue18
Capturing Differential Quality of Experimental Evidence in a Predictive Quantum-Mechanical Model for Respiratory Sensitization18
Integrative Data Mining Approach: Case Study with Adverse Outcome Pathway Network Leading to Pulmonary Fibrosis18
Detection of Trace Skin Sensitizers Using Novel Nucleophiles with Quaternary Ammonium by Liquid Chromatography–Mass Spectrometry18
Aldehyde-Associated Mutagenesis─Current State of Knowledge17
Navigating Transcriptomic Connectivity Mapping Workflows to Link Chemicals with Bioactivities17
Black Raspberry Extract Enhances Glutathione Conjugation of the Fjord-Region Diol Epoxide Derived from the Tobacco Carcinogen Dibenzo[def,p]chrysene in Human Oral Cells17
CYP3A4-Mediated Metabolic Activation and Cytotoxicity of Chlortoluron17
Deep Learning Models Compared to Experimental Variability for the Prediction of CYP3A4 Time-Dependent Inhibition17
Circular RNAs: A Potential Regulator in Environmental Chemical Carcinogenesis17
Heterogeneous Oxidation Products of Fine Particulate Isoprene Epoxydiol-Derived Methyltetrol Sulfates Increase Oxidative Stress and Inflammatory Gene Responses in Human Lung Cells17
Diethylhexyl Phthalate and Bisphenol A Promote Vincristine and Tamoxifen Resistancein Vitro17
Dopamine Release Impairments Accompany Locomotor and Cognitive Deficiencies in Rotenone-Treated Parkinson’s Disease Model Zebrafish17
Cytocompatibility of Ti3C2Tx MXene with Red Blood Cells and Human Umbilical Vein Endothelial Cells and the Underlying Mechanisms17
Issue Publication Information17
Metabolic Activation and Cytotoxicity of Propafenone Mediated by CYP2D617
Correction to “Use of Structural Alerts for Reactive Metabolites in the Application SpotRM”16
A Photoinducible DNA Cross-Linking Agent with Potent Cytotoxicity and Selectivity Toward Triple-Negative Breast Cancer Cell Line16
Novel In Vitro Intestinal Microbiome Model to Study Lipidomic and Metabolomic Adaptations Due to Exposure to Glyphosate, Perfluorooctanoic Acid, and Docusate Sodium16
Characterization of a Novel Thermostable DNA Lyase Used To Prepare DNA for Next-Generation Sequencing16
Call for Papers for a Special Issue on Mass Spectrometry Advances for Environmental and Human Health16
Binding of Per- and Polyfluoroalkyl Substances to β-Lactoglobulin from Bovine Milk16
The Genotoxicity of Stress16
Photosensitizing Properties of the Topical Retinoid Drug Adapalene16
Increased JUUL Emissions from Initial Puffs after Removing and Reinserting Pod15
A Catecholaldehyde Metabolite of Norepinephrine Induces Myofibroblast Activation and Toxicity via the Receptor for Advanced Glycation Endproducts: Mitigating Role of l-Carnosine15
Phthalate Exposure: Prevalence, Health Effects, Regulatory Frameworks, and Remediation15
Screening DNA Damage in the Rat Kidney and Liver by Untargeted DNA Adductomics15
Butyl Benzyl Phthalate Promotes Adipogenesis in 3T3-L1 Cells via the miRNA-34a-5p Signaling Pathway in the Absence of Exogenous Adipogenic Stimuli15
Issue Editorial Masthead15
Metabolomic Study on Iohexol-Induced Nephrotoxicity in Rats Based on NMR and LC–MS Analyses15
Cell Painting and Chemical Structure Read-Across Can Complement Each Other for Rat Acute Oral Toxicity Prediction in Chemical Early Derisking15
Issue Publication Information15
Introduction to the Special Issue: AI Meets Toxicology15
Role of Human Aldo–Keto Reductases in the Nitroreduction of 1-Nitropyrene and 1,8-Dinitropyrene14
Issue Editorial Masthead14
Hazard Profiling of Commercially Relevant Quantum Dot Components Revealed Synergistic Interactions between Heavy Metals and Polymers14
Natural Products in Redox Toxicology14
Activation of V-Domain Immunoglobulin Suppressor of T-Cell Activation by Baloxavir Marboxil Ameliorates Systemic Lupus Erythematosus through Inhibiting Lysophosphatidylcholine/CD40 Ligand14
Correction to “Structure-Based Reactivity Profiles of Reactive Metabolites with Glutathione”14
One-Week Kava Dietary Supplementation Increases Both Urinary N- and O-Glucuronides of NNAL, a Lung Carcinogen Major Metabolite, among Smokers14
Nuclear DNA and Mitochondrial Damage of the Cooked Meat Carcinogen 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in Human Neuroblastoma Cells14
Bioactivation of the β-Amyloid Precursor Protein-Cleaving Enzyme 1 Inhibitor Atabecestat Leads to Protein Adduct Formation on Glutathione S-Transferase Pi13
Facile Biological Oxidation of Dopamine to 6-Hydroxydopamine p-Quinone in a Sequential Two-Step Process: Implications for Parkinson’s Disease13
Issue Editorial Masthead13
Mechanisms Mediating the Combined Toxicity of Paraquat and Maneb in SH-SY5Y Neuroblastoma Cells13
Cannabidiol Toxicity Driven by Hydroxyquinone Formation13
Tox24 Challenge13
Women in Toxicology Special Issue13
Dissolution Rate of Nanomaterials Determined by Ions and Particle Size under Lysosomal Conditions: Contributions to Standardization of Simulant Fluids and Analytical Methods13
Issue Publication Information13
Issue Publication Information13
A Computational Approach for Respiratory Hazard Identification of Flavor Chemicals in Tobacco Products13
Furan Metabolites Are Elevated in Users of Various Tobacco Products and Cannabis13
Spatiotemporal Visualization of Paraquat Distribution, Toxicokinetics, and Its Detoxification in Zebrafish Using Matrix-Assisted Laser Desorption Ionization Mass Spectrometry Imaging13
Cadmium Exposure and Cardiovascular Diseases13
Issue Publication Information13
New Aminobiphenylcysteine Derivatives in Globin and Urine of Rats Dosed with 4-Aminobiphenyl, a Tobacco Smoke Carcinogen13
Nicotine Dosimetry in Evaluating Electronic Cigarettes Compared to Cigarette Smoking: Implications for Tobacco Regulatory Science13
8-Oxo-2′-deoxyguanosine Replication in Mutational Hot Spot Sequences of the p53 Gene in Human Cells Is Less Mutagenic than That of the Corresponding Formamidopyrimidine13
Idiosyncratic Drug Reactions: A 35-Year Chemical Research in Toxicology Perspective12
Nrf2 Activation Mitigates Silver Nanoparticle-Induced Ferroptosis in Hepatocytes12
Liver and Intestinal Fatty Acid Binding Proteins Are Not Critical for Perfluorooctanesulfonate (PFOS) Tissue Distribution and Elimination in Mice12
Chemoproteomic Approach for the Quantitative Identification of Arsenic-Binding Proteins12
P38 MAPK, NF-κB, and JAK-STAT3 Signaling Pathways Involved in Capecitabine-Induced Hand-Foot Syndrome via Interleukin 6 or Interleukin 8 Abnormal Expression12
Interindividual Variability in Cytochrome P450 3A and 1A Activity Influences Sunitinib Metabolism and Bioactivation12
Computer-Aided Discovery and Redesign for Respiratory Sensitization: A Tiered Mechanistic Model to Deliver Robust Performance Across a Diverse Chemical Space12
Human Keratinocyte Responses to Woodsmoke Chemicals12
Modelling In vitro Mutagenicity Using Multi-Task Deep Learning and REACH Data12
Honoring Larry Marnett, Founding Editor of Chemical Research in Toxicology12
Recent Contributions of Mass Spectrometry-Based “Omics” in the Studies of Breast Cancer12
Profiling How the Gut Microbiome Modulates Host Xenobiotic Metabolism in Response to Benzo[a]pyrene and 1-Nitropyrene Exposure12
Examining Metal Contents in Primary and Secondhand Aerosols Released by Electronic Cigarettes12
Production of Peroxymonocarbonate by Steady-State Micromolar H2O2 and Activated Macrophages in the Presence of CO2/HCO3 Evidenced by Boronate Pr12
Interview with Professor Cynthia J. Burrows, 2022 Founders Award Winner, American Chemical Society Division of Chemical Toxicology12
New Insights into the Phototoxicity of Anthracene-Based Chromophores: The Chloride Salt Effect11
A New Explanation for the Mystery of Rasputin’s Survival of Cyanide Poisoning: Eating Raw Garlic11
Chlorogenic Acid Alleviates Early-Life GenX Exposure-Induced Neurotoxicity via Decreasing Lipopolysaccharide-Induced Pyroptosis by the Systemic Translocation and Suppressing the PI3K/AKT/NF-κB Pathway11
Quantification of Intracellular DNA–Protein Cross-Links with N7-Methyl-2′-Deoxyguanosine and Their Contribution to Cytotoxicity11
Histotoxicity of AIEgen Based on Triphenylamine for the Simultaneous and Discriminatory Sensing of Hg2+ and Ag+ Directly in Aqueous Media for Environmental Applications11
Ultrafast Reaction of the Drug Hydralazine with Apurinic/Apyrimidinic Sites in DNA Gives Rise to a Stable Triazolo[3,4-a]phthalazine Adduct11
Effects of E-Cigarette Flavor Enhancing Capsules on Inhalable Aerosols11
Inhibitory Effects of Alkaloids on OATP1B1 In Vitro and In Vivo: Prediction for Food/Herb–Drug Interactions and Hepatoprotective Effects Based on Structure–Activity Relationships11
Machine Learning Models for Predicting Cytotoxicity of Nanomaterials11
High-Field Asymmetric Waveform Ion Mobility Spectrometry Analysis of Carcinogenic Aromatic Amines in Tobacco Smoke with an Orbitrap Tribrid Mass Spectrometer11
Quantitation of Ten Urinary Nicotine Metabolites, Including 4-Hydroxy-4-(3-pyridyl) Butanoic Acid, a Product of Nicotine 2′-Oxidation, and CYP2A6 Activity in Japanese Americans, Native Hawaiians, and 11
Correction to “Oxymatrine Inhibits Liver Cancer Progression by Regulating SIRT1/YY1/GPX4 Axis-Mediated Ferroptosis”11
Human CYP2C19 Substrate and Inhibitor Characterization of Organophosphate Pesticides11
Special Issue on Tobacco: Chemistry, Mechanisms, Biomarkers and Disease Prevention11
Multiplatform Metabolomics to Understand the Imidacloprid-Induced Toxicity in Drosophila11
Pyrroloquinoline Quinone Chemistry, Biology, and Biosynthesis11
Long Noncoding RNA MIAT Modulates Chronic Retinal Ischemia-Reperfusion Injury in Mice via the microRNA-203-3p/SNAI2 Axis11
Phthalate Exposure and Coronary Heart Disease: Possible Implications of Oxidative Stress and Altered miRNA Expression11
Antioxidant Activity and Skin Sensitization of Eugenol and Isoeugenol: Two Sides of the Same Coin?11
The Dawn of a New Era in Drug Discovery? Drug Screening and the Increasing Biological Complexity of Testing Models11
Berberine Inhibits KLF4 Promoter Methylation and Ferroptosis to Ameliorate Diabetic Nephropathy in Mice10
Identification of the Major Product of Guanine Oxidation in DNA by Ozone10
Pesticides Inhibit Retinoic Acid Catabolism in PLHC-1 and ZFL Fish Hepatic Cell Lines10
MlrA, an Essential Enzyme for Microcystins and Nodularin on First Step Biodegradation in Microcystin-Degrading Bacteria10
Formation Mechanism and Toxicological Significance of Biogenic Mercury Selenide Nanoparticles in Human Hepatoma HepG2 Cells10
Chlorpyrifos Oxon Activates Glutamate and Lysine for Protein Cross-linking10
Novel Dual PPAR δ/γ Partial Agonist Induces Hepatic Lipid Accumulation through Direct Binding and Inhibition of AKT1 Phosphorylation, Mediating CD36 Upregulation10
Prediction of Internal Exposures after Virtual Oral Doses of Disparate Chemicals in Rats and Humans Using Simplified Physiologically Based Pharmacokinetic Models with In Silico-Generated Input 10
Enantiomeric Fractions Reveal Differences in the Atropselective Disposition of 2,2′,3,5′,6-Pentachlorobiphenyl (PCB 95) in Wildtype, Cyp2abfgs-Null, and CYP2A6-Humanized Mice10
A Classification Model to Identify Direct-Acting Mutagenic Polycyclic Aromatic Hydrocarbon Transformation Products10
Review of the Protective Effects of Selenium against T-2 Toxin-Induced Toxicity10
Nucleophilic Addition of Thiols to Methacrylates for Biomedical Applications Revisited10
Carbonyls and Aerosol Mass Generation from Vaping Nicotine Salt Solutions Using Fourth- and Third-Generation E-Cigarette Devices: Effects of Coil Resistance, Coil Age, and Coil Metal Material10
Increased Levels of the Acrolein Metabolite 3-Hydroxypropyl Mercapturic Acid in the Urine of e-Cigarette Users10
Polyamine Adducts with AP Sites: Interaction with DNA Polymerases and AP Endonucleases10
Combining Molecular Docking and Pharmacophore Models Predicts Ligand Binding of Endocrine-Disrupting Chemicals to Nuclear Receptors10
Inhibition of Nicotine Metabolism by Cannabidiol (CBD) and 7-Hydroxycannabidiol (7-OH-CBD)10
Chlorobenzoquinones Aggravate RSL3-Induced Ferroptosis in ROS-Dependent Manner10
The Challenge and Opportunity to Rationally Design Safer Commercial Chemicals10
8-OxodGuo and Fapy•dG Mutagenicity in Escherichia coli Increases Significantly when They Are Part of a Tandem Lesion with 5-Formyl-2′-deoxyuridine9
Chemical Exposures and Impact on Health9
Isotope Labeling Mass Spectrometry to Quantify Endogenous and Exogenous DNA Adducts and Metabolites of 1,3-Butadiene In Vivo9
Metabolic Characterization of Sarin, Cyclosarin, and Novichoks (A-230, A-232) in Human Liver Microsomes9
The Effects of Polychlorinated Biphenyl Exposure During Adolescence on the Nervous System: A Comprehensive Review9
Mixtures-Inclusive In Silico Models of Ocular Toxicity Based on United States and International Hazard Categories9
Evaluation of Six Aromatic Amines in the Mainstream Smoke of Commercial Cigars9
Assessment of the Exposure to Tobacco-Specific Nitrosamines and Minor Tobacco Alkaloids in Users of Various Tobacco/Nicotine Products9
In Vitro Evaluation of DNA Damage Effect Markers toward Five Nitrogen Mustards Based on Liquid Chromatography–Tandem Mass Spectrometry9
The Human Glyoxalase Gene Family in Health and Disease9
Identification of Metoprolol Tartrate-Derived Reactive Metabolites Possibly Correlated with Its Cytotoxicity9
Ambient Fine Particulate Matter and Cancer: Current Evidence and Future Perspectives9
Machine Learning for Toxicity Prediction Using Chemical Structures: Pillars for Success in the Real World9
Issue Publication Information9
Evidence for the Metabolic Activation of Deferasirox In Vitro and In Vivo9
Natural Product Baohuoside I Impairs the Stability and Membrane Location of MRP2 Reciprocally Regulated by SUMOylation and Ubiquitination in Hepatocytes9
Searching for LINCS to Stress: Using Text Mining to Automate Reference Chemical Curation9
Synergistic Interaction of Polycyclic Aromatic Hydrocarbons, Phthalate Esters, or Phenol on DNA Adduct Formation by Aristolochic Acid I: Insights into the Etiology of Balkan Endemic Nephropathy9
Is Baikiain in Tara Flour a Causative Agent for the Adverse Events Associated with the Recalled Frozen French Lentil & Leek Crumbles Food Product? - A Working Hypothesis9
MetSim: Integrated Programmatic Access and Pathway Management for Xenobiotic Metabolism Simulators8
Urinary Profile of Alkylated DNA Adducts and DNA Oxidative Damage in Sulfur Mustard-Exposed Rats Revealed by Mass Spectrometry Quantification8
Ratiometric Fluorescent Probe for the Detection of Nanomolar Phosgene in Solution and Gaseous Phase: Advancing Crime Detection Applications8
Advances on the Influence of Methylmercury Exposure during Neurodevelopment8
Issue Publication Information8
Nuclear SUMOylation and Proteotoxic Stress Responses to Metals with Different Ligand Preferences8
Quantification of Flavors, Volatile Organic Compounds, Tobacco Markers, and Tobacco-Specific Nitrosamines in Heated Tobacco Products and Their Mainstream Aerosol8
Nature-Derived Epoxy Resin Monomers with Reduced Sensitizing Capacity─Isosorbide-Based Bis-Epoxides8
Potential Role of Heterocyclic Aromatic Amines in Neurodegeneration8
A Virtual Issue of Chemical Research in Toxicology in Celebration of the International Day of Women and Girls in Science8
Toxic Effects of Cobalt on Erythroid Progenitor Cells8
Network Pharmacology Combined with Metabolomics Approach to Investigate the Toxicity Mechanism of Paclobutrazol8
Quantum Chemical Evaluation and QSAR Modeling of N-Nitrosamine Carcinogenicity8
Introducing the Inaugural Early Career Board for Chemical Research in Toxicology8
A Membrane Biophysics Perspective on the Mechanism of Alcohol Toxicity8
Data Exploration for Target Predictions Using Proprietary and Publicly Available Data Sets8
Oxidation of Naringenin, Apigenin, and Genistein by Human Family 1 Cytochrome P450 Enzymes and Comparison of Interaction of Apigenin with Human P450 1B1.1 and Scutellaria P450 82D.18
Carbonyl Emissions and Heating Temperatures across 75 Nominally Identical Electronic Nicotine Delivery System Products: Do Manufacturing Variations Drive Pulmonary Toxicant Exposure?8
Role of Human Aldo-Keto Reductases and Nuclear Factor Erythroid 2-Related Factor 2 in the Metabolic Activation of 1,8-Dinitropyrene and Its Metabolite 1-Amino-8-nitropyrene via Nitroreduction in Human8
Issue Editorial Masthead8
Driving to a Better Understanding of Acyl Glucuronide Transformations Using NMR and Molecular Modeling8
Interview with Dr. Wei Yang, 2022 Keynote Speaker, American Chemical Society Division of Chemical Toxicology8
Characterization of Catecholaldehyde Adducts with Carnosine and l-Cysteine Reveals Their Potential as Biomarkers of Catecholaminergic Stress8
Identification of Specific Hemoglobin Adduct Patterns in Users of Different Tobacco/nicotine Products by Nontargeted GC–MS/MS Analysis8
Influence of Nitrite on Formation of Tobacco-Specific Nitrosamines in Electronic Cigarette Liquids and Aerosols8
Improving Volatile Organic Compound Exposure Assessment Using Biomonitoring by Relating Exposure Biomarker Levels in Blood and Urine8
Protease-Activated Receptor 2 (PAR-2) Antagonist AZ3451 Mitigates Oxidized Low-Density Lipoprotein (Ox-LDL)-Induced Damage and Endothelial Inflammation8
Migration of Soluble Polymers in Human Saliva during Swabbing Characterized by Direct Electrospray Ionization Mass Spectrometry8
Issue Editorial Masthead8
Dried Matrix Spots: An Underutilized and Unexplored Technology in India8
The Potential Contribution of Hexavalent Chromium to the Carcinogenicity of Chrysotile Asbestos8
Effects of N7-Alkylguanine Conformation and Metal Cofactors on the Translesion Synthesis by Human DNA Polymerase η8
Conformation and Pairing Properties of anO6-Methyl-2′-deoxyguanosine-Directed Benzimidazole Nucleoside Analog in Duplex DNA8
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