Chemical Research in Toxicology

Article	Citations
Elevating Research and Careers in the Development of Safer Drugs through Artificial Intelligence	85
Oxidative Deformylation of the Predominant DNA Lesion 5-Formyl-2′-deoxyuridine	78
Capture of Electrophilic Quinones in the Extracellular Space: Evidence for a Phase Zero Reaction	69
Mechanistic Insights into Toxicity of Titanium Dioxide Nanoparticles at the Micro- and Macro-levels	69
Recent Advances in DNA Lesion Mapping and Repair Mechanisms	66
Electrochemical Simulation of the Oxidative Capsaicin Metabolism	55
Predicting Liver-Related In Vitro Endpoints with Machine Learning to Support Early Detection of Drug-Induced Liver Injury	53
Coumarin-Based Noncytotoxicity Fluorescent Dye for Tracking Actin Protein in In-Vivo Imaging	50
Dissecting the Enantioselective Neurotoxicity of Isocarbophos: Chiral Insight from Cellular, Molecular, and Computational Investigations	50
Surfactant Coformulants in Glyphosate-Based Herbicides: Current Gaps, and Paths Forward in Human Biomonitoring	50
LA-ICP-MS and Immunohistochemical Staining with Lanthanide-Labeled Antibodies to Study the Uptake of CeO2 Nanoparticles by Macrophages in Tissue Sections	49
Advances in Metabolism and Metabolic Toxicology of Quinoxaline 1,4-Di-N-oxides	47
A Weakly Supervised Deep Learning Framework for Whole Slide Classification to Facilitate Digital Pathology in Animal Study	45
In Vitro and In Vivo Analysis of Fentanyl and Fentalog Metabolites using Hyphenated Chromatographic Techniques: A Review	44
Systematic Investigation of CYP3A4 Using Side-by-Side Comparisons of Apo, Active Site, and Allosteric-Bound States	40
Identification of an Epoxide Metabolite of Amitriptyline In Vitro and In Vivo	40
Alternaria alternata Mycotoxins Activate the Aryl Hydrocarbon Receptor and Nrf2-ARE Pathway to Alter the Structure and Immune Response of Colon Epithelial Cells	39
Application of Covalent Binding Body Burden in the HμREL Human Hepatocyte Coculture Model for Reactivity Risk Assessment of Metabolically Low Turnover Drugs	37
Bioaccumulation and DNA Adduct Formation of Aristolactam I: Unmasking a Toxicological Mechanism in the Pathophysiology of Aristolochic Acid Nephropathy	37
Issue Publication Information	37
Issue Publication Information	36
Issue Editorial Masthead	34
Protein Haptenation and Its Role in Allergy	33
Issue Editorial Masthead	33
Cellular Interactions and Fatty Acid Transporter CD36-Mediated Uptake of Per- and Polyfluorinated Alkyl Substances (PFAS)	32

A Review on the Recent Applications of Deep Learning in Predictive Drug Toxicological Studies	31
Mass Spectrometry-Based Metabolic Profiling of Urinary Metabolites of N′-Nitrosonornicotine (NNN) in the Rat	29
Telmisartan Mitigates High-Glucose-Induced Injury in Renal Glomerular Endothelial Cells (rGECs) and Albuminuria in Diabetes Mice	29
Underlying Mechanisms of Allopurinol in Eliminating Renal Toxicity Induced by Melamine–Uric Acid Complex Formation: A Computational Study	29
Nonclinical Safety Signals in PharmaPendium Improve the Predictability of Human Drug-Induced Liver Injury	29
ZIM, a Norbornene Derived from 4-Aminoantipyrine, Induces DNA Damage and Cell Death but in Association Reduces the Effect of Commercial Chemotherapeutics	27
The Toxicity of Poly(acrylonitrile-styrene–butadiene) Microplastics toward Hyalella azteca Is Associated with Biofragmentation and Oxidative Stress	27
Leveraging Cell Painting Images to Expand the Applicability Domain and Actively Improve Deep Learning Quantitative Structure–Activity Relationship Models	27
Computational Prediction of Metabolic α-Carbon Hydroxylation Potential ofN-Nitrosamines: Overcoming Data Limitations for Carcinogenicity Assessment	27
Structural Elucidation of Agrochemical Metabolic Transformation Products Based on Infrared Ion Spectroscopy to Improve In Silico Toxicity Assessment	26
Photosensitized Oxidation of Free and Peptide Tryptophan to N-Formylkynurenine	26
Modeling the Toxicokinetics of Suspensions of Soluble Metallic Nanomaterials	26
Characterization of Teicoplanin-Specific T-Cells from Drug Naïve Donors Expressing HLA-A*32:01	25
Quantum-Mechanical Approach to Predicting the Carcinogenic Potency of N-Nitroso Impurities in Pharmaceuticals	25
2,2′,4,4′-Tetrabromodiphenyl Ether (PBDE 47) Selectively Stimulates Proatherogenic PPARγ Signatures in Human THP-1 Macrophages to Contribute to Foam Cell Formation	25
Potential Involvement of Sulfotransferase in the Mechanism of Lamotrigine-induced Skin Rash	24
Products Generated by Amine-Catalyzed Strand Cleavage at Apurinic/Apyrimidinic Sites in DNA: New Insights from a Biomimetic Nucleoside Model System	24
LC–MS/MS Analysis of Reaction Products of Arginine/Methylarginines with Methylglyoxal/Glyoxal	24
Conditional Binding of Arsenic Trioxide (ATO) to Cysteine-Rich Zinc Finger Motifs within RBCC Domain of PML Protein	23
Quantum Mechanical Assessment of Nitrosamine Potency	23
Response to ‘Comments on “Tobacco-Specific Nitrosamines in the Tobacco and Mainstream Smoke of Commercial Little Cigars”’ Letter to Editor	23
Assessing the Toxicity of Terpene- and Amino Acid-Based Natural Deep Eutectic Solvents	23
Prediction of Cytochrome P450 Substrates Using the Explainable Multitask Deep Learning Models	22
Metals in Cannabis Vaporizer Aerosols: Sources, Possible Mechanisms, and Exposure Profiles	22
Advancing Drug Safety in Drug Development: Bridging Computational Predictions for Enhanced Toxicity Prediction	22
HDAC6-Mediated NLRP3 Inflammasome Activation Is Involved in Nickel Nanoparticle-Induced Pulmonary Inflammation and Fibrosis	22
Issue Editorial Masthead	21
Characterizing the Chemical Landscape in Commercial E-Cigarette Liquids and Aerosols by Liquid Chromatography–High-Resolution Mass Spectrometry	21
Issue Editorial Masthead	20
Federated Learning in Computational Toxicology: An Industrial Perspective on the Effiris Hackathon	20
Issue Editorial Masthead	20
Issue Editorial Masthead	20
Black Raspberry Extract Enhances Glutathione Conjugation of the Fjord-Region Diol Epoxide Derived from the Tobacco Carcinogen Dibenzo[def,p]chrysene in Human Oral Cells	20
Acrylamide-Aggravated Liver Injury by Activating Endoplasmic Reticulum Stress in Female Mice with Diabetes	19
Nontargeted Analysis in Tobacco Research: Challenges and Opportunities	19
Diethylhexyl Phthalate and Bisphenol A Promote Vincristine and Tamoxifen Resistancein Vitro	19
Comment on Benzophenone Accumulates over Time from the Degradation of Octocrylene in Commercial Sunscreen Products	18
Zebrafish Larvae as a Predictive Model for the Risk of Chemical-Induced Cholestasis: Phenotypic Evaluation and Nomogram Formation	18
Detection of Trace Skin Sensitizers Using Novel Nucleophiles with Quaternary Ammonium by Liquid Chromatography–Mass Spectrometry	18
Heterogeneous Oxidation Products of Fine Particulate Isoprene Epoxydiol-Derived Methyltetrol Sulfates Increase Oxidative Stress and Inflammatory Gene Responses in Human Lung Cells	18
Simultaneous Quantification of Biomarkers for Bis-(2-chloroethyl) Sulfide and 1,2-Bis(2-chloroethylthio) Ethane Exposure in Human Urine at Trace Exposure Levels by Gas Chromatography Tandem Mass Spect	18
Melatonin Vapes Contain Potential Contaminants and Alter the Human Bronchial Epithelial Transcriptome	18
Aldehyde-Associated Mutagenesis─Current State of Knowledge	18
Cytocompatibility of Ti3C2Tx MXene with Red Blood Cells and Human Umbilical Vein Endothelial Cells and the Underlying Mechanisms	18
Free Radicals in Little Cigar Mainstream Smoke and the Potential Influence of Flavoring Chemicals on Free Radical Production	18
Deep Learning Models Compared to Experimental Variability for the Prediction of CYP3A4 Time-Dependent Inhibition	18
Chemoproteomic Approach for Identifying Nuclear Arsenite-Binding Proteins	18
Issue Publication Information	17
Nucleophilic Thiol Proteins Bind Covalently to Abasic Sites in DNA	17
Integrative Data Mining Approach: Case Study with Adverse Outcome Pathway Network Leading to Pulmonary Fibrosis	17

Metabolism-Coupled Cell-Independent Acetylcholinesterase Activity Assay for Evaluation of the Effects of Chlorination on Diazinon Toxicity	17
Metabolic Activation of Atomoxetine Mediated by Cytochrome P450 2D6	17
Capturing Differential Quality of Experimental Evidence in a Predictive Quantum-Mechanical Model for Respiratory Sensitization	17
Photo-oxidation and Photoreduction of Catechols by Chlorophyll Metabolites and Methylene Blue	16
Navigating Transcriptomic Connectivity Mapping Workflows to Link Chemicals with Bioactivities	16
Novel In Vitro Intestinal Microbiome Model to Study Lipidomic and Metabolomic Adaptations Due to Exposure to Glyphosate, Perfluorooctanoic Acid, and Docusate Sodium	16
Binding of Per- and Polyfluoroalkyl Substances to β-Lactoglobulin from Bovine Milk	16
Issue Editorial Masthead	16
CYP3A4-Mediated Metabolic Activation and Cytotoxicity of Chlortoluron	16
Issue Editorial Masthead	16
Metabolic Activation and Cytotoxicity of Propafenone Mediated by CYP2D6	16
A Photoinducible DNA Cross-Linking Agent with Potent Cytotoxicity and Selectivity Toward Triple-Negative Breast Cancer Cell Line	16
Dopamine Release Impairments Accompany Locomotor and Cognitive Deficiencies in Rotenone-Treated Parkinson’s Disease Model Zebrafish	16
Issue Publication Information	16
Photosensitizing Properties of the Topical Retinoid Drug Adapalene	16
Characterization of a Novel Thermostable DNA Lyase Used To Prepare DNA for Next-Generation Sequencing	16
Metabolomic Study on Iohexol-Induced Nephrotoxicity in Rats Based on NMR and LC–MS Analyses	15
A Catecholaldehyde Metabolite of Norepinephrine Induces Myofibroblast Activation and Toxicity via the Receptor for Advanced Glycation Endproducts: Mitigating Role of l-Carnosine	15
Introduction to the Special Issue: AI Meets Toxicology	15
The Genotoxicity of Stress	15
Screening DNA Damage in the Rat Kidney and Liver by Untargeted DNA Adductomics	15
Issue Publication Information	15
Phthalate Exposure: Prevalence, Health Effects, Regulatory Frameworks, and Remediation	15
Butyl Benzyl Phthalate Promotes Adipogenesis in 3T3-L1 Cells via the miRNA-34a-5p Signaling Pathway in the Absence of Exogenous Adipogenic Stimuli	15
Correction to “Use of Structural Alerts for Reactive Metabolites in the Application SpotRM”	15
Role of Human Aldo–Keto Reductases in the Nitroreduction of 1-Nitropyrene and 1,8-Dinitropyrene	15
Issue Editorial Masthead	15
Cell Painting and Chemical Structure Read-Across Can Complement Each Other for Rat Acute Oral Toxicity Prediction in Chemical Early Derisking	15
Increased JUUL Emissions from Initial Puffs after Removing and Reinserting Pod	15
Call for Papers for a Special Issue on Mass Spectrometry Advances for Environmental and Human Health	15
Correction to “Structure-Based Reactivity Profiles of Reactive Metabolites with Glutathione”	14
Hazard Profiling of Commercially Relevant Quantum Dot Components Revealed Synergistic Interactions between Heavy Metals and Polymers	14
One-Week Kava Dietary Supplementation Increases Both Urinary N- and O-Glucuronides of NNAL, a Lung Carcinogen Major Metabolite, among Smokers	14
Natural Products in Redox Toxicology	14
Activation of V-Domain Immunoglobulin Suppressor of T-Cell Activation by Baloxavir Marboxil Ameliorates Systemic Lupus Erythematosus through Inhibiting Lysophosphatidylcholine/CD40 Ligand	14
Recent Contributions of Mass Spectrometry-Based “Omics” in the Studies of Breast Cancer	13
Issue Publication Information	13
Nuclear DNA and Mitochondrial Damage of the Cooked Meat Carcinogen 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in Human Neuroblastoma Cells	13
Idiosyncratic Drug Reactions: A 35-Year Chemical Research in Toxicology Perspective	13
Nicotine Dosimetry in Evaluating Electronic Cigarettes Compared to Cigarette Smoking: Implications for Tobacco Regulatory Science	13
Issue Editorial Masthead	13
Issue Editorial Masthead	13
New Aminobiphenylcysteine Derivatives in Globin and Urine of Rats Dosed with 4-Aminobiphenyl, a Tobacco Smoke Carcinogen	13
Cannabidiol Toxicity Driven by Hydroxyquinone Formation	13
Spatiotemporal Visualization of Paraquat Distribution, Toxicokinetics, and Its Detoxification in Zebrafish Using Matrix-Assisted Laser Desorption Ionization Mass Spectrometry Imaging	13
Examining Metal Contents in Primary and Secondhand Aerosols Released by Electronic Cigarettes	13
Issue Publication Information	13
Issue Publication Information	13
Mechanisms Mediating the Combined Toxicity of Paraquat and Maneb in SH-SY5Y Neuroblastoma Cells	13
A Computational Approach for Respiratory Hazard Identification of Flavor Chemicals in Tobacco Products	13
P38 MAPK, NF-κB, and JAK-STAT3 Signaling Pathways Involved in Capecitabine-Induced Hand-Foot Syndrome via Interleukin 6 or Interleukin 8 Abnormal Expression	12
Dissolution Rate of Nanomaterials Determined by Ions and Particle Size under Lysosomal Conditions: Contributions to Standardization of Simulant Fluids and Analytical Methods	12
Interindividual Variability in Cytochrome P450 3A and 1A Activity Influences Sunitinib Metabolism and Bioactivation	12
Computer-Aided Discovery and Redesign for Respiratory Sensitization: A Tiered Mechanistic Model to Deliver Robust Performance Across a Diverse Chemical Space	12
Profiling How the Gut Microbiome Modulates Host Xenobiotic Metabolism in Response to Benzo[a]pyrene and 1-Nitropyrene Exposure	12
Phthalate Exposure and Coronary Heart Disease: Possible Implications of Oxidative Stress and Altered miRNA Expression	12
Human Keratinocyte Responses to Woodsmoke Chemicals	12
8-Oxo-2′-deoxyguanosine Replication in Mutational Hot Spot Sequences of the p53 Gene in Human Cells Is Less Mutagenic than That of the Corresponding Formamidopyrimidine	12
Women in Toxicology Special Issue	12
Tox24 Challenge	12
Facile Biological Oxidation of Dopamine to 6-Hydroxydopamine p-Quinone in a Sequential Two-Step Process: Implications for Parkinson’s Disease	12
Production of Peroxymonocarbonate by Steady-State Micromolar H2O2 and Activated Macrophages in the Presence of CO2/HCO3– Evidenced by Boronate Pr	12
Furan Metabolites Are Elevated in Users of Various Tobacco Products and Cannabis	12
Cadmium Exposure and Cardiovascular Diseases	12
Bioactivation of the β-Amyloid Precursor Protein-Cleaving Enzyme 1 Inhibitor Atabecestat Leads to Protein Adduct Formation on Glutathione S-Transferase Pi	12
Long Noncoding RNA MIAT Modulates Chronic Retinal Ischemia-Reperfusion Injury in Mice via the microRNA-203-3p/SNAI2 Axis	12
Quantitation of Ten Urinary Nicotine Metabolites, Including 4-Hydroxy-4-(3-pyridyl) Butanoic Acid, a Product of Nicotine 2′-Oxidation, and CYP2A6 Activity in Japanese Americans, Native Hawaiians, and	11
Honoring Larry Marnett, Founding Editor of Chemical Research in Toxicology	11
Machine Learning Models for Predicting Cytotoxicity of Nanomaterials	11
Berberine Inhibits KLF4 Promoter Methylation and Ferroptosis to Ameliorate Diabetic Nephropathy in Mice	11
Chlorobenzoquinones Aggravate RSL3-Induced Ferroptosis in ROS-Dependent Manner	11
New Insights into the Phototoxicity of Anthracene-Based Chromophores: The Chloride Salt Effect	11
Quantification of Intracellular DNA–Protein Cross-Links with N7-Methyl-2′-Deoxyguanosine and Their Contribution to Cytotoxicity	11
Interview with Professor Cynthia J. Burrows, 2022 Founders Award Winner, American Chemical Society Division of Chemical Toxicology	11
Pyrroloquinoline Quinone Chemistry, Biology, and Biosynthesis	11
Ultrafast Reaction of the Drug Hydralazine with Apurinic/Apyrimidinic Sites in DNA Gives Rise to a Stable Triazolo[3,4-a]phthalazine Adduct	11
The Dawn of a New Era in Drug Discovery? Drug Screening and the Increasing Biological Complexity of Testing Models	11
Special Issue on Tobacco: Chemistry, Mechanisms, Biomarkers and Disease Prevention	11
Histotoxicity of AIEgen Based on Triphenylamine for the Simultaneous and Discriminatory Sensing of Hg2+ and Ag+ Directly in Aqueous Media for Environmental Applications	11
Chemoproteomic Approach for the Quantitative Identification of Arsenic-Binding Proteins	11

High-Field Asymmetric Waveform Ion Mobility Spectrometry Analysis of Carcinogenic Aromatic Amines in Tobacco Smoke with an Orbitrap Tribrid Mass Spectrometer	11
Correction to “Oxymatrine Inhibits Liver Cancer Progression by Regulating SIRT1/YY1/GPX4 Axis-Mediated Ferroptosis”	11
Human CYP2C19 Substrate and Inhibitor Characterization of Organophosphate Pesticides	11
Effects of E-Cigarette Flavor Enhancing Capsules on Inhalable Aerosols	11
A New Explanation for the Mystery of Rasputin’s Survival of Cyanide Poisoning: Eating Raw Garlic	11
Antioxidant Activity and Skin Sensitization of Eugenol and Isoeugenol: Two Sides of the Same Coin?	10
Increased Levels of the Acrolein Metabolite 3-Hydroxypropyl Mercapturic Acid in the Urine of e-Cigarette Users	10
Polyamine Adducts with AP Sites: Interaction with DNA Polymerases and AP Endonucleases	10
Chlorpyrifos Oxon Activates Glutamate and Lysine for Protein Cross-linking	10
MlrA, an Essential Enzyme for Microcystins and Nodularin on First Step Biodegradation in Microcystin-Degrading Bacteria	10
Inhibitory Effects of Alkaloids on OATP1B1 In Vitro and In Vivo: Prediction for Food/Herb–Drug Interactions and Hepatoprotective Effects Based on Structure–Activity Relationships	10
8-OxodGuo and Fapy•dG Mutagenicity in Escherichia coli Increases Significantly when They Are Part of a Tandem Lesion with 5-Formyl-2′-deoxyuridine	10
A Classification Model to Identify Direct-Acting Mutagenic Polycyclic Aromatic Hydrocarbon Transformation Products	10
Prediction of Internal Exposures after Virtual Oral Doses of Disparate Chemicals in Rats and Humans Using Simplified Physiologically Based Pharmacokinetic Models with In Silico-Generated Input	10
Enantiomeric Fractions Reveal Differences in the Atropselective Disposition of 2,2′,3,5′,6-Pentachlorobiphenyl (PCB 95) in Wildtype, Cyp2abfgs-Null, and CYP2A6-Humanized Mice	10
Isotope Labeling Mass Spectrometry to Quantify Endogenous and Exogenous DNA Adducts and Metabolites of 1,3-Butadiene In Vivo	10
Carbonyls and Aerosol Mass Generation from Vaping Nicotine Salt Solutions Using Fourth- and Third-Generation E-Cigarette Devices: Effects of Coil Resistance, Coil Age, and Coil Metal Material	10
Combining Molecular Docking and Pharmacophore Models Predicts Ligand Binding of Endocrine-Disrupting Chemicals to Nuclear Receptors	10
The Human Glyoxalase Gene Family in Health and Disease	10
Formation Mechanism and Toxicological Significance of Biogenic Mercury Selenide Nanoparticles in Human Hepatoma HepG2 Cells	10
Novel Dual PPAR δ/γ Partial Agonist Induces Hepatic Lipid Accumulation through Direct Binding and Inhibition of AKT1 Phosphorylation, Mediating CD36 Upregulation	10
Identification of the Major Product of Guanine Oxidation in DNA by Ozone	10
Searching for LINCS to Stress: Using Text Mining to Automate Reference Chemical Curation	10
Multiplatform Metabolomics to Understand the Imidacloprid-Induced Toxicity in Drosophila	10
Review of the Protective Effects of Selenium against T-2 Toxin-Induced Toxicity	10
Pesticides Inhibit Retinoic Acid Catabolism in PLHC-1 and ZFL Fish Hepatic Cell Lines	10
Evidence for the Metabolic Activation of Deferasirox In Vitro and In Vivo	9
In Vitro and In Vivo Studies of Metabolic Activation of Marrubiin, a Bioactive Constituent from Marrubium Vulgare	9
Issue Publication Information	9
Mixtures-Inclusive In Silico Models of Ocular Toxicity Based on United States and International Hazard Categories	9
Metabolic Characterization of Sarin, Cyclosarin, and Novichoks (A-230, A-232) in Human Liver Microsomes	9
Quantification of Flavors, Volatile Organic Compounds, Tobacco Markers, and Tobacco-Specific Nitrosamines in Heated Tobacco Products and Their Mainstream Aerosol	9
Ambient Fine Particulate Matter and Cancer: Current Evidence and Future Perspectives	9
Chemical Exposures and Impact on Health	9
In Vitro Evaluation of DNA Damage Effect Markers toward Five Nitrogen Mustards Based on Liquid Chromatography–Tandem Mass Spectrometry	9
Natural Product Baohuoside I Impairs the Stability and Membrane Location of MRP2 Reciprocally Regulated by SUMOylation and Ubiquitination in Hepatocytes	9
Synergistic Interaction of Polycyclic Aromatic Hydrocarbons, Phthalate Esters, or Phenol on DNA Adduct Formation by Aristolochic Acid I: Insights into the Etiology of Balkan Endemic Nephropathy	9
The Effects of Polychlorinated Biphenyl Exposure During Adolescence on the Nervous System: A Comprehensive Review	9
Assessment of the Exposure to Tobacco-Specific Nitrosamines and Minor Tobacco Alkaloids in Users of Various Tobacco/Nicotine Products	9
Inhibition of Nicotine Metabolism by Cannabidiol (CBD) and 7-Hydroxycannabidiol (7-OH-CBD)	9
Is Baikiain in Tara Flour a Causative Agent for the Adverse Events Associated with the Recalled Frozen French Lentil & Leek Crumbles Food Product? - A Working Hypothesis	9
Evaluation of Six Aromatic Amines in the Mainstream Smoke of Commercial Cigars	9
Machine Learning for Toxicity Prediction Using Chemical Structures: Pillars for Success in the Real World	9
Identification of Metoprolol Tartrate-Derived Reactive Metabolites Possibly Correlated with Its Cytotoxicity	9
Ratiometric Fluorescent Probe for the Detection of Nanomolar Phosgene in Solution and Gaseous Phase: Advancing Crime Detection Applications	9
Conformation-Dependent Lesion Bypass and Mutagenicity of Bulky 2-Acetylaminofluorene-Guanine DNA Adduct in Epigenetically Relevant Sequence Contexts	8
Potential Role of Heterocyclic Aromatic Amines in Neurodegeneration	8
Protease-Activated Receptor 2 (PAR-2) Antagonist AZ3451 Mitigates Oxidized Low-Density Lipoprotein (Ox-LDL)-Induced Damage and Endothelial Inflammation	8
Improving Volatile Organic Compound Exposure Assessment Using Biomonitoring by Relating Exposure Biomarker Levels in Blood and Urine	8
Nature-Derived Epoxy Resin Monomers with Reduced Sensitizing Capacity─Isosorbide-Based Bis-Epoxides	8
Nuclear SUMOylation and Proteotoxic Stress Responses to Metals with Different Ligand Preferences	8
Quantum Chemical Evaluation and QSAR Modeling of N-Nitrosamine Carcinogenicity	8
Driving to a Better Understanding of Acyl Glucuronide Transformations Using NMR and Molecular Modeling	8
High-Throughput Screening of ToxCast PFAS Chemical Library for Potential Inhibitors of the Human Sodium Iodide Symporter	8
Conformation and Pairing Properties of anO6-Methyl-2′-deoxyguanosine-Directed Benzimidazole Nucleoside Analog in Duplex DNA	8
Characterization of Catecholaldehyde Adducts with Carnosine and l-Cysteine Reveals Their Potential as Biomarkers of Catecholaminergic Stress	8
Carbonyl Emissions and Heating Temperatures across 75 Nominally Identical Electronic Nicotine Delivery System Products: Do Manufacturing Variations Drive Pulmonary Toxicant Exposure?	8
Issue Publication Information	8
Data Exploration for Target Predictions Using Proprietary and Publicly Available Data Sets	8
A Membrane Biophysics Perspective on the Mechanism of Alcohol Toxicity	8
Migration of Soluble Polymers in Human Saliva during Swabbing Characterized by Direct Electrospray Ionization Mass Spectrometry	8
A Novel Inhibitor of Poly(ADP-Ribose) Polymerase-1 Inhibits Proliferation of a BRCA-Deficient Breast Cancer Cell Line via the DNA Damage–Activated cGAS–STING	8
Formation of DHP-DNA Adducts from Rat Liver Microsomal Metabolism of 1,2-Unsaturated Pyrrolizidine Alkaloid-Containing Plant Extracts and Dietary Supplements	8
Effects of N7-Alkylguanine Conformation and Metal Cofactors on the Translesion Synthesis by Human DNA Polymerase η	8
Urinary Profile of Alkylated DNA Adducts and DNA Oxidative Damage in Sulfur Mustard-Exposed Rats Revealed by Mass Spectrometry Quantification	8
Network Pharmacology Combined with Metabolomics Approach to Investigate the Toxicity Mechanism of Paclobutrazol	8
MetSim: Integrated Programmatic Access and Pathway Management for Xenobiotic Metabolism Simulators	8
Influence of Nitrite on Formation of Tobacco-Specific Nitrosamines in Electronic Cigarette Liquids and Aerosols	8
Issue Editorial Masthead	8
Advances on the Influence of Methylmercury Exposure during Neurodevelopment	8
Oxidation of Naringenin, Apigenin, and Genistein by Human Family 1 Cytochrome P450 Enzymes and Comparison of Interaction of Apigenin with Human P450 1B1.1 and Scutellaria P450 82D.1	8
Dried Matrix Spots: An Underutilized and Unexplored Technology in India	8
Role of Human Aldo-Keto Reductases and Nuclear Factor Erythroid 2-Related Factor 2 in the Metabolic Activation of 1,8-Dinitropyrene and Its Metabolite 1-Amino-8-nitropyrene via Nitroreduction in Human	8
A Virtual Issue of Chemical Research in Toxicology in Celebration of the International Day of Women and Girls in Science	8
Toxic Effects of Cobalt on Erythroid Progenitor Cells	8
Identification of Specific Hemoglobin Adduct Patterns in Users of Different Tobacco/nicotine Products by Nontargeted GC–MS/MS Analysis	8
Using High-Throughput Screening to Evaluate Perturbations Potentially Linked to Neurobehavioral Outcomes: A Case Study Using Publicly Available Tools on FDA Batch-Certified Synthetic Food Dyes	8