Journal of Investigative Surgery

Article	Citations
MiR-15a-5p Knockdown up-Regulated ABCB1 Expression and Abated HNSCC Progression via the NF-κB Signaling Pathway	302
Comprehensive Assessment of Inflammatory Indices to Predict Outcomes in Acute Pancreatitis	57
circ-Gucy1a2 Protects Mice from Cerebral Ischemia-Reperfusion Injury by Attenuating Neuronal Apoptosis and Mitochondrial Membrane Potential Loss	43
The Impact of Screw Density on the Outcomes of Adolescent Idiopathic Scoliosis Correction Surgery: A Multicenter Retrospective Study	31
Acteoside Derived from Cistanche Improves Glucocorticoid-Induced Osteoporosis by Activating PI3K/AKT/mTOR Pathway	31
Letter to the Editor: “Systemic Inflammation Response Index and Systemic Immune Inflammation Index Are Associated with Clinical Outcomes in Patients with Acute Pancreatitis”	30
Laparoscopic Surgery for Superior Mesenteric Artery Syndrome	24
Single-Incision Plus One Port Laparoscopic Surgery for Myomectomy: A Retrospective Study	23
Recurrence and Survival Rates of Patients Who Undergo Minimally Invasive Surgery for Endometrial Carcinoma with Different Prognostic Risk Groups	21
Is Tumor Regression Grade Sufficient to Predict Survival in Esophageal Cancer with Trimodal Therapy?	18
Combined HIF-1α and SHH Up-Regulation Is a Potential Biomarker to Predict Poor Prognosis in Postoperative Hepatocellular Carcinoma	18
Effects of Preoperative Anti-TNF Therapy on Specimen Length in Crohn’s Disease and Beyond	18
Indocyanine Green Angiography of Parathyroid Glands versus Intraoperative Parathyroid Hormone Assay as a Reliable Predictor for Post Thyroidectomy Transient Hypocalcemia	15
Open Radiofrequency Ablation Combined with Splenectomy and Pericardial Devascularization vs. Liver Transplantation for Hepatocellular Carcinoma Patients with Portal Hypertension and Hypersplenism: A C	15
Femoral Neck System versus Three Cannulated Screws for Fixation of Femoral Neck Fractures in Younger Patients: A Retrospective Cohort Study	14
Foxo3a-Mediated DNMT3B Impedes Cervical Cancer Cell Proliferation and Migration Capacities through Suppressing PTEN Promoter Methylation	14
Diagnostic Potential of Circulating lncRNA SNHG5 in Osteoporotic Fractures and Its Mechanistic Role in Accelerating Fracture Healing	11
Minimally Invasive Concepts in Treating Synchronous Liver Metastases Rectal Cancer Patients: Report of Six Cases	11
The Safety of Primary Anastomosis Without Protective Stoma in Emergency Left Colon Surgery: A Meta-Analysis	11
Comparative Analysis of Postoperative Recovery and Analgesia in Gynecologic Laparoscopic Surgery with Total Intravenous Anesthesia Versus Combined Intravenous Inhalational Anesthesia Both with Ultraso	11
Association Between Atrial Fibrillation and Atherosclerosis in Patients with Acute Lower Limb Arterial Ischemia: A Retrospective Cohort Study	11
Randomized Single-Center Study of Effectiveness and Safety of a Resorbable Lysine-Based Urethane Adhesive for a Drain-Free Closure of the Abdominal Donor Site in a DIEP Flap Breast Reconstruction Proc	10
A Large Segmental Mid-Diaphyseal Femoral Defect Sheep Model: Surgical Technique	10
Effect of Negative Pressure Wound Therapy on Surgical Site Infections following Stoma Reversal in Colorectal Surgery: A Meta-Analysis	9
The Effect of Adipose Derived Stromal Vascular Fraction on Flap Viability in Experimental Diabetes Mellitus and Chronic Renal Disease	9

Predictors of Pain Development after Laparoscopic Adnexectomy: A Still Open Challenge	9
Expression Significance and Prognostic Value of GPR27 in Ovarian Cancer	9
Regarding: ”Enhancing Outcomes in Transarterial Embolization for Late Postpancreatectomy Hemorrhage: A Comparison of N-Butyl Cyanoacrylate with Mixed Embolic Agents Versus Mixed Embolic Agents Alone”	9
Jump Technique versus Seton Method for Anal Fistula Repair: A Randomized Controlled Trial	9
Anterior, Posterior and Anterior–Posterior Approaches for the Treatment of Thoracolumbar Burst Fractures: A Network Meta-Analysis of Randomized Controlled Trials	8
Supracondylar Humerus Fractures in Infants and Toddlers: An Unexplored Area	7
Investigation of the Gastroprotective Effect of Betaine-Homocysteine Homeostasis on Oxidative Stress, Inflammation and Apoptosis in Ethanol-Induced Ulcer Model	7
Effects of Mesalamine Combined with Live Combined Bifidobacterium, Lactobacillus and Enterococcus Capsules on Intestinal Mucosa Barrier Function and Intestinal Microbiota in Mildly Active Crohn’s Dise	7
Efficacy of Adjuvant Transarterial Chemoembolization after Radical Hepatectomy in Solitary Hepatocellular Carcinoma Patients: A Retrospective Study	7
A Porcine Model of Laparoscopic Intersphincteric Resection for Ultra-Low Rectal Cancer	7
What Are the Characteristics of Papillary Thyroid Microcarcinoma Prone to High-Volume Lateral Lymph Node Metastasis? - An Analysis of 2981 Consecutive Cases	7
The Impact of Minimally Invasive Surgery on Treating Patients with Early Cervical Adenocarcinoma	7
Effects of Botulinum Toxin A on the Blood Flow in Expanded Rat Skin	7
Is PSA Still the Best Predictor for Biochemical Recurrence after Radical Prostatectomy in High-Risk Prostate Cancer?	6
Norepinephrine Infusion and the Central Venous Waveform in a Porcine Model of Endotoxemic Hypotension with Resuscitation: A Large Animal Study	6
Effect of Prior Bariatric Surgery on the Outcomes of Joint Arthroplasty: A Systematic Review and Meta-Analysis	6
Functional Study of the circRNA_0006393/miR-375/IGFBP4 Axis in Fracture Healing Associated with Male Idiopathic Osteoporosis	6
Female Iliac Vein Variations: Risk of Injury and May-Thurner Syndrome	6
Deciphering the Function of lncRNA XIST/miR-329-3p/TMBIM6 Axis in the Proliferation of Non-Small Cell Lung Cancer	6
Lutein Protects Ischemic Skin Flaps via Antioxidant and Anti-Inflammatory Mechanisms in a Rat Model of Ischemia-Reperfusion Injury	6
Effects of Driving Pressure-Guided Ventilation on Postoperative Pulmonary Complications in Prone-Positioned Patients Undergoing Spinal Surgery: A Randomized Controlled Clinical Trial	6
Relationship between NLR and PLR Ratios and the Occurrence and Prognosis of Progressive Hemorrhagic Injury in Patients with Traumatic Brain Injury	6
Post-Operative Day Zero Discharge after Laparoscopic Appendectomy Does Not Worsen High-Yield Outcomes: A NSQIP Database Observational Study	6
Verteporfin Suppresses YAP-Induced Glycolysis in Breast Cancer Cells	5
Establishment and Validation of Diagnostic Model of Microvascular Invasion in Solitary Hepatocellular Carcinoma	5
Near-Infrared Autofluorescence Imaging in Thyroid Surgery: A Systematic Review and Meta-Analysis	5
Neutrophil-to-Hemoglobin Ratio and Monocyte-to-Hemoglobin Ratio Predict Prolonged Length of Stay in Patients Undergoing Surgery for Pelvic or Acetabular Fractures	5
The HIF-1α/PKM2 Feedback Loop in Relation to EGFR Mutational Status in Lung Adenocarcinoma	5
Systemic Inflammation Response Index and Systemic Immune Inflammation Index Are Associated with Clinical Outcomes in Patients with Acute Pancreatitis?	5
An Epidemiological Study on Survival in Lymphoma of Mucosa-Associated Lymphoid Tissue: A Comparative Analysis by Primary Tumor Location	5
A Randomized Controlled Trial Assessing the Impact of Transcutaneous Electrical Acupoint Stimulation on Gastrointestinal Motility, Nutritional Status, and Immune Function in Patients Following Cerebro	5
A Novel Nomogram for Prediction of Survival in Patients with Small Isolated Hepatocellular Carcinoma: A Population-Based and Externally Validated Study	5
Mini-Review: Tendon-Exposed Wound Treatments	5
Survival Benefit of Radical Prostatectomy in Newly Diagnosed Metastatic Prostate Cancer Varies by PSA Level and Site of Metastasis	5
Combining Clinical Parameters and Immunohistochemical Markers Might Strengthen Prediction of Recurrence of Non-Muscle Invasive Bladder Cancer	5
RIP1 Regulates Mitochondrial Fission during Skeletal Muscle Ischemia Reperfusion Injury	5
Low Energy Ultrapulse CO 2 Fractional Laser Combined with Autologous Platelet-Rich Plasma in Periorbital Rejuvenation Treatment	5
The Effects of Radioiodine Therapy on the Recovery of Parathyroid Function in Patients with Protracted Hypoparathyroidism after Total Thyroidectomy for Papillary Thyroid Carcinoma	4
Correlation of Preoperative Serum and Intraoperative Peritoneal Lavage Fluid Ca-125 Levels with Postoperative Tumor Histology in Patients with Endometrial Cancer: A Prospective-Controlled Study	4
A Narrative Review of Nutritional Therapy for Gastrointestinal Cancer Patients Underwent Surgery	4
Relationship between Primary Tumor Resection for Metastatic Small Intestine Neuroendocrine Tumors and Survival: A Propensity Score-Matched Analysis	4
Correction	4
Clinical and Microbial Features of Granulomatous Mastitis: Comparative Analysis of Breast and Gut Microbiota	4
Parallel Cross-Leg Free Flap with Posterior Tibial Artery Perforator Pedicle Propeller Cable Bridge Flap for the Treatment of Lower Extremity Wounds: A Case Series Report	4
Incidence, Prognostic Factors, and Survival of Patients with Renal Cancer: A Population-Based Study	4
Eye-Tracking Indicators of Workload in Surgery: A Systematic Review	4
The Use of Social Media to Deliver Surgical Education in Response to the COVID-19 Pandemic	4
Free Tissue Transfer in Single Vessel Lower Leg: What Is New?	4
S100 Calcium-Binding Protein A8 Functions as a Tumor-Promoting Factor in Renal Cell Carcinoma via Activating NF-κB Signaling Pathway	4
Degree of Soft Tissue Injury is a Major Determinant of Successful Arterial Repair in the Extremity: A New Classification of Extremity Arterial Injury?	4

Tissue Adhesive: Current Uses and Strengths	4
Impact of Diameter of Perforator in Pedicle and Different Managements of Intermediate Non-Pedicle Perforator on Flap Survival in Rats	3
The Comparison of Postoperative Analgesic Efficacy of Ultrasound-Guided Paravertebral Block and Mid-Point Transverse Process Pleura Block in Mastectomy Surgeries: A Randomized Study	3
Survival Between Mastectomy and Breast-Conserving Surgery in De Novo Metastatic Breast Cancer: A Propensity Score-Matched Study	3
Mechanical Bowel Preparation Can Be Omitted in the Modern Era of Minimally Invasive Gynaecological Surgery and ERAS Pathways	3
Active Intra-Abdominal Drainage Following Abdominal Digestive System Surgery: A Meta-Analysis and Systematic Review	3
Comparative Analysis of the Superior Mesenteric Artery and Modified SMA Approaches in Totally Laparoscopic Radical Resection for Right Colon Cancer: Impact on Operative Outcomes and Complications	3
Developments in the Diagnosis and Management of Cholecystoenteric Fistula	3
Correction	3
Arterial and Soft Tissue Injury of the Extremities: A Challenging Clinical Scenario	3
S2-Alar-Iliac Screw Fixation versus Iliac Screw Fixation in the Treatment of Sacral Fractures	3
Impact of Adjuvant Chemotherapy on Survival of the Patients with pT1N + M0 Gastric Cancer: A Retrospective Cohort Study	3
The Epidermal Barrier Structure and Function of Re-Harvested Skin from Non-Scalp Donor Sites	3
Comparison of Percutaneous Nephrostomy and Ureteral DJ Stent in Patients with Obstructive Pyelonephritis: A Retrospective Cohort Study	3
Prognostic Value of Inflammatory Markers in HBV-Related HCC After Hepatectomy Based on a Clinical Database	3
Pancreatic Cancer: A Review of Current Treatment and Novel Therapies	3
What is a predictive role of acute-phase serum Amyloid in the prognosis of patients with hepatocellular carcinoma?	3
A Modified Chen’s U-Suture Technique with or Without a Stent in Pancreaticojejunostomy for Patients with Soft Pancreas and Small Pancreatic Duct: A Multicenter Cohort Study	3
Surgical Treatment of Ectopic Mediastinal Parathyroid Tumors: A 23-Year Clinical Data Study in a Single Center	3
Protective Effects of Hydrogen-Rich Saline on Experimental Intestinal Volvulus in Rats	3
Authors’ Reply to the Letter to the Editor: “Comprehensive Assessment of Inflammatory Indices to Predict Outcomes in Acute Pancreatitis”	3
Predictive Model for Sciatic Nerve Block Efficacy Based on Perfusion Index and Regional Blood Flow Changes	3
Modified Frailty Index Combined with a Prognostic Nutritional Index for Predicting Postoperative Complications of Hip Fracture Surgery in Elderly	3
Lymphadenectomy in Primary Fallopian Tube Cancer is Associated with Improved Survival	2
Statement of Retraction: Liver X Receptors Activation Attenuates Ischemia Reperfusion Injury of Liver Graft in Rats	2
PPARγ Mediates Protective Effect against Hepatic Ischemia/Reperfusion Injury via NF-κB Pathway	2
Developing an Animal Model for Swenson Transanal Endorectal Pull-Through: A New Possibility for Training and Research Purposes	2
Prognostic Value of Tumor Deposit Counts in Patients with Stage III Colorectal Cancer: A Population-Based Study	2
The Effect of Mechanical Bowel Preparation on the Surgical Field in Laparoscopic Gynecologic Surgeries: A Prospective Randomized Controlled Trial	2
Comparison of Intraoperative Endplate Injury between Mini-Open Lateral Lumbar Interbody Fusion (LLIF) and Transforaminal Lumbar Interbody Fusion (TLIF) and Analysis of Risk Factors: A Retrospective St	2
Splenic Abscesses in Endocarditis: A Rare Disease with High Mortality. The Experience of a Heart Institute in Brazil	2
Feasibility of Magnetic Technique for Axillary Staging after Neoadjuvant Therapy in Breast Cancer Patients	2
Surgical Procedures Required for Measurement Reduce Nerve Conduction Velocity: An In Vivo and In Vitro Comparative Study	2
Mild Hypothermia via External Cooling Improves Lung Function and Alleviates Pulmonary Inflammatory Response and Damage in Two-Hit Rabbit Model of Acute Lung Injury	2
Impact of Treatment Strategies on Survival and Within Multivariate Predictive Model for Renal Cell Carcinoma Based on the SEER Database: A Retrospective Cohort Study	2
The Effect of Antioxidant Astaxanthin on Intestinal Ischemia Reperfusion Damage in Rats	2
Racial and Socioeconomic Disparities in Necrotizing Soft-Tissue Infection	2
Preoperative Simulation and Three-Dimensional Model for the Operative Treatment of Forearm Double Fracture: A Randomized Controlled Clinical Trial	2
Measuring the Systemic Inflammatory Response to On- and Off-Pump Coronary Artery Bypass Graft (CABG) Surgeries Using the Tryptophan/Kynurenine Pathway	2
Prognostic Factors and Management Approaches for Small Nonfunctional Pancreatic Neuroendocrine Tumors: Insights from SEER Data	2
Sonographic Endometrial Characteristics Associated with Subsequent Surgical Intervention After Medical Termination of Early Pregnancy Loss: A Single-Center Retrospective Cohort Study	2
The Comparative Effects of Inulin and Bacillus clausii on LPS-Induced Endotoxemic Rat Liver	2
Quantification of Dermal Microcirculatory Changes after Topical Administration of Capsaicin: A Randomized Placebo-Controlled Study in 46 Subjects	2
Percutaneous Functional Spinal Unit Cementoplasty versus Posterior Spinal Fixation with Vertebroplasty for Symptomatic Chronic Osteoporotic Vertebral Fractures: A Retrospective Study with a 2-Year Fol	2
Relationship Between Changes in the Expression Levels of miR-134 and E2F6 in Mediating Control of Apoptosis in NMDA-Induced Glaucomatous Mice	2
Prognostic Value of Tumor Regression Grade Combined with Pathological Lymph Node Status in Initially Node-Positive Rectal Cancer Treated with Neoadjuvant Chemoradiotherapy	2
Association Between Adenomyosis and Cervical Cancer: A Retrospective Cohort Study	1
Correlation Between Basal Metabolic Rate and Clinical Outcomes in Gastric Cancer Patients: A Retrospective Study	1
Can Uterine Septum be an Etiological Factor for Dysmenorrhea in Primary Infertile Patients?	1
Feasibility and Prognostic Analysis of Neoadjuvant Therapy Followed by Breast-Conserving Surgery for Invasive Ductal Carcinoma Combined with Ductal Carcinoma in Situ	1
Application of Problem-Based Learning Combined with Micro-Video Teaching in Burn Surgery and Its Impact on Satisfaction with Teaching	1
Clinical, Histological, and Profibrotic Extracellular Matrix Protein Changes in a Model of Tracheal Stenosis Induced by Cervical Tracheal Autotransplantation	1
Association of Log Odds of Positive Lymph Nodes with Overall Survival in Patients with Primary Malignant Anorectal Melanoma: A Population-Based Study	1
Utilization of Perifascial Loose Areolar Tissue Grafting as an Autologous Dermal Substitute in Extremity Burns	1
Effectiveness Analysis of Sevoflurane Combined with Propofol or Remimazolam Anesthesia in Pediatric Laparoscopic Inguinal Hernia Repair and Its Impact on Hemodynamics and Postoperative Pain	1
Peripheral Immunophenotype in the Diagnosis of Mesenteric Ischemia in Rats: An Experimental Study	1
Accurate Neurosurgery for the Establishment of the Electric Kindling Model of Epilepsy in Mice	1
Inhibition of Caspase-11-Mediated Pyroptosis Alleviates Acute Kidney Injury Associated with Severe Acute Pancreatitis in Rats	1
Role of SFRP5 in Non-Small Cell Lung Cancer and Its Correlation with SUV of 18F-FDG PET-CT	1
Modified Intrascleral Suture Technique for Repairing Iridodialysis Combined with Phacoemulsification Cataract Surgery	1
Application of Cyclosporine A Plus Zishen Yutai Pill in the Treatment of Patients with Recurrent Pregnancy Loss	1
Three-Dimensional in Vivo Anatomical Study of Female Iliac Vein Variations	1
Extended Ligation of the Hepatic Vein May Yield a Similar Effect to Liver Venous Deprivation in a Rat Model	1
Laparoscopic Interval Debulking Surgery for Ovarian Cancer: Fagotti versus PCI Score for Patients’ Selection	1
Supracondylar Humerus Fractures in Infants and Early Toddlers; Characteristics, Clinical and Radiological Outcomes Compared with Older Children	1
Effects of Hsa-miR-4741/LILRB2 on Senescence of Nucleus Pulposus Cells and Their Prognostic Values in Lumbar Disc Herniation	1
Perioperative Complications and Postoperative Mortality in Patients of Acute Stanford Type a Aortic Dissection with Cardiac Tamponade	1
Current Research Describing the Role of CD4+ T Lymphocyte Subsets in the Pathogenesis of Granulomatous Lobular Mastitis	1
Recognizing and Managing Pancreaticopleural Fistulas in Children	1
Predicting the Risk of Postoperative Delirium in Elderly Patients Undergoing Hip Arthroplasty: Development and Assessment of a Novel Nomogram	1
miR-637 Inhibits Osteogenic Differentiation of Human Intervertebral Disc Cartilage Endplate Stem Cells by Targeting WNT5A	1
Comparative Study of Complications and Incision Esthetic Satisfaction Between Single-Port Laparoscopy and Traditional Laparoscopy in Benign Gynecological Surgery	1
Lactate Dehydrogenase and Risk of Readmission with Gastric Cancer: A Propensity Score Matching Analysis	1
A Preoperative Noninvasive Index Prediction Model for TURP Surgical Outcomes in Patients with Benign Prostatic Hyperplasia	1
Prostate Cancer Nomograms Are Still Alive	1
Establishment of Prognostic Nomograms for Early-Onset Prostate Cancer Patients: A SEER Database Analysis	1
A Proposed Nomogram Model for Recurrence of Non-Muscle Invasive Bladder Carcinoma	1
Optimized Minimally Invasive Jejunoileal Bypass Compared to Traditional Minimally Invasive Jejunoileal Bypass in the Treatment of Type 2 Diabetes: A Retrospective Cohort Study	1
Our Results of Hyperbaric Oxygen or Pars Plana Vitrectomy in Central Retinal Artery Obstruction	1
Relation Between Serum Sodium Trajectory and Survival in Septic Patients with Cardiopulmonary Bypass Surgery: Based on Medical Information Mart for Intensive Care-IV Database	1

The Influence of Growth Blocking of the Neurocentral Cartilages on the Development of the Spinal Canal. An Experimental Study in Pigs	1
The Future of Surgical Education Today	1