Neuron

Article	Citations
The Bidirectional Relationship of Depression and Inflammation: Double Trouble	837
Microglia states and nomenclature: A field at its crossroads	465
Astrocyte Crosstalk in CNS Inflammation	420
Neurodevelopment of the association cortices: Patterns, mechanisms, and implications for psychopathology	273
COVID-19 and the Chemical Senses: Supporting Players Take Center Stage	252
Transcriptional Reprogramming of Distinct Peripheral Sensory Neuron Subtypes after Axonal Injury	250
Psilocybin induces rapid and persistent growth of dendritic spines in frontal cortex in vivo	210
White matter aging drives microglial diversity	209
ALS Genetics: Gains, Losses, and Implications for Future Therapies	209
Thalamus Modulates Consciousness via Layer-Specific Control of Cortex	204
Beyond t test and ANOVA: applications of mixed-effects models for more rigorous statistical analysis in neuroscience research	182
Somatotopic Organization and Intensity Dependence in Driving Distinct NPY-Expressing Sympathetic Pathways by Electroacupuncture	177
SARM1 is a metabolic sensor activated by an increased NMN/NAD+ ratio to trigger axon degeneration	168
How Can Hearing Loss Cause Dementia?	167
Individual Variation in Functional Topography of Association Networks in Youth	163
Systematic Integration of Structural and Functional Data into Multi-scale Models of Mouse Primary Visual Cortex	155
Enhancing myelin renewal reverses cognitive dysfunction in a murine model of Alzheimer’s disease	155
High-Contrast In Vivo Imaging of Tau Pathologies in Alzheimer’s and Non-Alzheimer’s Disease Tauopathies	153
LTP Induction Boosts Glutamate Spillover by Driving Withdrawal of Perisynaptic Astroglia	153
Selective removal of astrocytic APOE4 strongly protects against tau-mediated neurodegeneration and decreases synaptic phagocytosis by microglia	150
The different autophagy degradation pathways and neurodegeneration	150
Artificial Neural Networks for Neuroscientists: A Primer	149
Early-life inflammation promotes depressive symptoms in adolescence via microglial engulfment of dendritic spines	148
Cell Type-Specific Transcriptomics Reveals that Mutant Huntingtin Leads to Mitochondrial RNA Release and Neuronal Innate Immune Activation	146
Behaviorally consequential astrocytic regulation of neural circuits	143

Whole-Brain Profiling of Cells and Circuits in Mammals by Tissue Clearing and Light-Sheet Microscopy	142
Prefrontal-Subthalamic Hyperdirect Pathway Modulates Movement Inhibition in Humans	142
Divergent Neural Pathways Emanating from the Lateral Parabrachial Nucleus Mediate Distinct Components of the Pain Response	142
Alzheimer’s Risk Factors Age, APOE Genotype, and Sex Drive Distinct Molecular Pathways	141
The neurobiology of long COVID	141
Behavior needs neural variability	138
Transcriptomic taxonomy and neurogenic trajectories of adult human, macaque, and pig hippocampal and entorhinal cells	138
Apolipoprotein E: Structural Insights and Links to Alzheimer Disease Pathogenesis	137
Structure of the Native Muscle-type Nicotinic Receptor and Inhibition by Snake Venom Toxins	136
Trem2 restrains the enhancement of tau accumulation and neurodegeneration by β-amyloid pathology	136
Single-Cell Sequencing of Brain Cell Transcriptomes and Epigenomes	135
Emerging Microglia Biology Defines Novel Therapeutic Approaches for Alzheimer’s Disease	133
A Primer on Motion Capture with Deep Learning: Principles, Pitfalls, and Perspectives	130
Astrocytes and oligodendrocytes undergo subtype-specific transcriptional changes in Alzheimer’s disease	128
Imaging Neurotransmitter and Neuromodulator Dynamics In Vivo with Genetically Encoded Indicators	128
Ultrasound Technologies for Imaging and Modulating Neural Activity	123
ApoE Cascade Hypothesis in the pathogenesis of Alzheimer’s disease and related dementias	121
The Sensory Coding of Warm Perception	120
Pathogenic DDX3X Mutations Impair RNA Metabolism and Neurogenesis during Fetal Cortical Development	117
Circuitry Underlying Experience-Dependent Plasticity in the Mouse Visual System	115
Transcriptional Programs of Circuit Assembly in the Drosophila Visual System	115
Shaping Neuronal Fate: Functional Heterogeneity of Direct Microglia-Neuron Interactions	113
Tau aggregates are RNA-protein assemblies that mislocalize multiple nuclear speckle components	111
Magnetoelectric Materials for Miniature, Wireless Neural Stimulation at Therapeutic Frequencies	110
CD49f Is a Novel Marker of Functional and Reactive Human iPSC-Derived Astrocytes	110
Plasticity and Spontaneous Activity Pulses in Disused Human Brain Circuits	109
Map Making: Constructing, Combining, and Inferring on Abstract Cognitive Maps	108
Optimizing Nervous System-Specific Gene Targeting with Cre Driver Lines: Prevalence of Germline Recombination and Influencing Factors	108
Gender bias in academia: A lifetime problem that needs solutions	106
Targeting Homeostatic Synaptic Plasticity for Treatment of Mood Disorders	105
Sensory Experience Engages Microglia to Shape Neural Connectivity through a Non-Phagocytic Mechanism	105
Area Postrema Cell Types that Mediate Nausea-Associated Behaviors	103
Single cortical neurons as deep artificial neural networks	103
The population doctrine in cognitive neuroscience	103
Ultra-slow Oscillations in fMRI and Resting-State Connectivity: Neuronal and Vascular Contributions and Technical Confounds	102
Transformative Network Modeling of Multi-omics Data Reveals Detailed Circuits, Key Regulators, and Potential Therapeutics for Alzheimer’s Disease	102
Deep Reinforcement Learning and Its Neuroscientific Implications	101
Assembly-Specific Disruption of Hippocampal Replay Leads to Selective Memory Deficit	100
A Distributed Neural Code in the Dentate Gyrus and in CA1	100
Mechanical Allodynia Circuitry in the Dorsal Horn Is Defined by the Nature of the Injury	99
Selective Neuronal Vulnerability in Alzheimer’s Disease: A Network-Based Analysis	98
Single-nucleus transcriptome analysis reveals cell-type-specific molecular signatures across reward circuitry in the human brain	98
Sex-Specific Role for the Long Non-coding RNA LINC00473 in Depression	98
Transcriptional and Spatial Resolution of Cell Types in the Mammalian Habenula	96
Brain-behavior correlations: Two paths toward reliability	95
Enhancer viruses for combinatorial cell-subclass-specific labeling	95
All-Electrical Ca2+-Independent Signal Transduction Mediates Attractive Sodium Taste in Taste Buds	93
Unraveling circuits of visual perception and cognition through the superior colliculus	93
Regional, Layer, and Cell-Type-Specific Connectivity of the Mouse Default Mode Network	92
An Ultra-Sensitive Step-Function Opsin for Minimally Invasive Optogenetic Stimulation in Mice and Macaques	91

Rewiring of human neurodevelopmental gene regulatory programs by human accelerated regions	91
Integrative Benchmarking to Advance Neurally Mechanistic Models of Human Intelligence	91
Fovea-like Photoreceptor Specializations Underlie Single UV Cone Driven Prey-Capture Behavior in Zebrafish	91
Whole-Neuron Synaptic Mapping Reveals Spatially Precise Excitatory/Inhibitory Balance Limiting Dendritic and Somatic Spiking	90
Virus exposure and neurodegenerative disease risk across national biobanks	90
Comprehensive Dual- and Triple-Feature Intersectional Single-Vector Delivery of Diverse Functional Payloads to Cells of Behaving Mammals	90
IL-23/IL-17A/TRPV1 axis produces mechanical pain via macrophage-sensory neuron crosstalk in female mice	89
G4C2 Repeat RNA Initiates a POM121-Mediated Reduction in Specific Nucleoporins in C9orf72 ALS/FTD	89
Dopaminergic Transmission Rapidly and Persistently Enhances Excitability of D1 Receptor-Expressing Striatal Projection Neurons	89
Arousal Modulates Retinal Output	89
Region-Specific Transcriptional Control of Astrocyte Function Oversees Local Circuit Activities	88
Autism-Associated Shank3 Is Essential for Homeostatic Compensation in Rodent V1	88
Continuous Whole-Body 3D Kinematic Recordings across the Rodent Behavioral Repertoire	87
Replay bursts in humans coincide with activation of the default mode and parietal alpha networks	87
Neuronal Autophagy Regulates Presynaptic Neurotransmission by Controlling the Axonal Endoplasmic Reticulum	87
Behavioral, Physiological, and Neural Signatures of Surprise during Naturalistic Sports Viewing	87
Tipping the Scales: Peptide-Dependent Dysregulation of Neural Circuit Dynamics in Alzheimer’s Disease	86
Neuronal Activity Regulates Blood-Brain Barrier Efflux Transport through Endothelial Circadian Genes	85
The mouse prefrontal cortex: Unity in diversity	85
Neural circuits of social behaviors: Innate yet flexible	85
A Neural Network for Wind-Guided Compass Navigation	84
Opposing Influence of Top-down and Bottom-up Input on Excitatory Layer 2/3 Neurons in Mouse Primary Visual Cortex	84
The Neuroanatomical Ultrastructure and Function of a Biological Ring Attractor	84
Hippocampal replay reflects specific past experiences rather than a plan for subsequent choice	83
Precision Calcium Imaging of Dense Neural Populations via a Cell-Body-Targeted Calcium Indicator	83
Extraction of Distinct Neuronal Cell Types from within a Genetically Continuous Population	83
A mechanism for inter-areal coherence through communication based on connectivity and oscillatory power	82
An Integrated Index: Engrams, Place Cells, and Hippocampal Memory	82
Neural Trajectories in the Supplementary Motor Area and Motor Cortex Exhibit Distinct Geometries, Compatible with Different Classes of Computation	82
Recent Advances in Electrical Neural Interface Engineering: Minimal Invasiveness, Longevity, and Scalability	82
Postingestive Modulation of Food Seeking Depends on Vagus-Mediated Dopamine Neuron Activity	81
Hyperscanning: Beyond the Hype	81
Mediodorsal and Ventromedial Thalamus Engage Distinct L1 Circuits in the Prefrontal Cortex	81
VTA Glutamate Neuron Activity Drives Positive Reinforcement Absent Dopamine Co-release	81
Rescuing Over-activated Microglia Restores Cognitive Performance in Juvenile Animals of the Dp(16) Mouse Model of Down Syndrome	81
VTA Glutamatergic Neurons Mediate Innate Defensive Behaviors	80
Translation of GGC repeat expansions into a toxic polyglycine protein in NIID defines a novel class of human genetic disorders: The polyG diseases	80
Slow Drift of Neural Activity as a Signature of Impulsivity in Macaque Visual and Prefrontal Cortex	79
Efficient optogenetic silencing of neurotransmitter release with a mosquito rhodopsin	79
Orthogonal representations for robust context-dependent task performance in brains and neural networks	78
Disrupted Place Cell Remapping and Impaired Grid Cells in a Knockin Model of Alzheimer's Disease	78
C9orf72 deficiency promotes microglial-mediated synaptic loss in aging and amyloid accumulation	77
Internal senses of the vagus nerve	77
A Disinhibitory Circuit for Contextual Modulation in Primary Visual Cortex	77
Astrocytes Control Sensory Acuity via Tonic Inhibition in the Thalamus	76
Robust Myelination of Regenerated Axons Induced by Combined Manipulations of GPR17 and Microglia	76
Prefrontal Cortex Predicts State Switches during Reversal Learning	76
SNAREopathies: Diversity in Mechanisms and Symptoms	76
An Open Resource for Non-human Primate Optogenetics	76
Large-Scale 3D Two-Photon Imaging of Molecularly Identified CA1 Interneuron Dynamics in Behaving Mice	75
Preexisting hippocampal network dynamics constrain optogenetically induced place fields	75
Hierarchical Representations of Aggression in a Hypothalamic-Midbrain Circuit	75
Stem cell-derived neurons reflect features of protein networks, neuropathology, and cognitive outcome of their aged human donors	75
Spontaneous activity in developing thalamic and cortical sensory networks	74
Precise Holographic Manipulation of Olfactory Circuits Reveals Coding Features Determining Perceptual Detection	74
Short-Term Plasticity at Hippocampal Mossy Fiber Synapses Is Induced by Natural Activity Patterns and Associated with Vesicle Pool Engram Formation	73
In vitro neurons learn and exhibit sentience when embodied in a simulated game-world	73
The Parabrachial Nucleus Directly Channels Spinal Nociceptive Signals to the Intralaminar Thalamic Nuclei, but Not the Amygdala	72
Context-Specific Striatal Astrocyte Molecular Responses Are Phenotypically Exploitable	72
Fast Recurrent Processing via Ventrolateral Prefrontal Cortex Is Needed by the Primate Ventral Stream for Robust Core Visual Object Recognition	71
Resolving cellular and molecular diversity along the hippocampal anterior-to-posterior axis in humans	71
Loss- or Gain-of-Function Mutations in ACOX1 Cause Axonal Loss via Different Mechanisms	71
Astrocytic ApoE reprograms neuronal cholesterol metabolism and histone-acetylation-mediated memory	71
Modulation of Human Memory by Deep Brain Stimulation of the Entorhinal-Hippocampal Circuitry	71
Differential Emergence and Stability of Sensory and Temporal Representations in Context-Specific Hippocampal Sequences	70
Sparse Activity of Hippocampal Adult-Born Neurons during REM Sleep Is Necessary for Memory Consolidation	70
Cue-Evoked Dopamine Promotes Conditioned Responding during Learning	70
TMIE Defines Pore and Gating Properties of the Mechanotransduction Channel of Mammalian Cochlear Hair Cells	70
A sensitive GRAB sensor for detecting extracellular ATP in vitro and in vivo	69
Specific populations of basal ganglia output neurons target distinct brain stem areas while collateralizing throughout the diencephalon	69
Cochlear neural degeneration disrupts hearing in background noise by increasing auditory cortex internal noise	69
Neural Sequences as an Optimal Dynamical Regime for the Readout of Time	69
Macrophages transfer mitochondria to sensory neurons to resolve inflammatory pain	69
Amygdala-Midbrain Connections Modulate Appetitive and Aversive Learning	69
A M/EEG-fMRI Fusion Primer: Resolving Human Brain Responses in Space and Time	68
Neuronal NLRP3 is a parkin substrate that drives neurodegeneration in Parkinson’s disease	67
Alternating sources of perisomatic inhibition during behavior	67
Oligodendrocytes enhance axonal energy metabolism by deacetylation of mitochondrial proteins through transcellular delivery of SIRT2	67
Prefrontal Cortex Corticotropin-Releasing Factor Neurons Control Behavioral Style Selection under Challenging Situations	67
The Loss of TBK1 Kinase Activity in Motor Neurons or in All Cell Types Differentially Impacts ALS Disease Progression in SOD1 Mice	67

Reconstruction of the Hypothalamo-Neurohypophysial System and Functional Dissection of Magnocellular Oxytocin Neurons in the Brain	67
Replay of Behavioral Sequences in the Medial Prefrontal Cortex during Rule Switching	66
Frequency of theta rhythm is controlled by acceleration, but not speed, in running rats	66
Regional Aβ-tau interactions promote onset and acceleration of Alzheimer’s disease tau spreading	66
Differential Coding of Itch and Pain by a Subpopulation of Primary Afferent Neurons	66
Context-Dependent Decision Making in a Premotor Circuit	65
Spatial goal coding in the hippocampal formation	65
The emergence and influence of internal states	65
Mesoscopic Imaging: Shining a Wide Light on Large-Scale Neural Dynamics	65
Orchestrating Opiate-Associated Memories in Thalamic Circuits	65
Programming axonal mitochondrial maintenance and bioenergetics in neurodegeneration and regeneration	64
Periaqueductal gray/dorsal raphe dopamine neurons contribute to sex differences in pain-related behaviors	64
Neural Correlates of Reinforcement Learning in Mid-lateral Cerebellum	64
A cerebellar-thalamocortical pathway drives behavioral context-dependent movement initiation	64
Viral Vectors for Neural Circuit Mapping and Recent Advances in Trans-synaptic Anterograde Tracers	64
The Anterior Cingulate Cortex Predicts Future States to Mediate Model-Based Action Selection	64
Activity-Dependent Plasticity of Axo-axonic Synapses at the Axon Initial Segment	64
Two Brain Pathways Initiate Distinct Forward Walking Programs in Drosophila	64
PNOCARC Neurons Promote Hyperphagia and Obesity upon High-Fat-Diet Feeding	64
Closed-Loop Theta Stimulation in the Orbitofrontal Cortex Prevents Reward-Based Learning	64
Constructing and Forgetting Temporal Context in the Human Cerebral Cortex	63
Spinal macrophages resolve nociceptive hypersensitivity after peripheral injury	63
Human and mouse trigeminal ganglia cell atlas implicates multiple cell types in migraine	63
Expanding evolutionary neuroscience: insights from comparing variation in behavior	63
A Platform for Brain-wide Volumetric Functional Ultrasound Imaging and Analysis of Circuit Dynamics in Awake Mice	62
Synapse and Active Zone Assembly in the Absence of Presynaptic Ca2+ Channels and Ca2+ Entry	62
Spaced Training Forms Complementary Long-Term Memories of Opposite Valence in Drosophila	62
A photoswitchable GPCR-based opsin for presynaptic inhibition	62
What Is the Relationship between Pain and Emotion? Bridging Constructs and Communities	61
The Raphe Dopamine System Controls the Expression of Incentive Memory	61
Tau Reduction Prevents Key Features of Autism in Mouse Models	60
Genome-wide In Vivo CNS Screening Identifies Genes that Modify CNS Neuronal Survival and mHTT Toxicity	60
Cell-type-specific binocular vision guides predation in mice	59
Cooling of Medial Septum Reveals Theta Phase Lag Coordination of Hippocampal Cell Assemblies	59
The Dentate Gyrus Classifies Cortical Representations of Learned Stimuli	59
Brain rhythms define distinct interaction networks with differential dependence on anatomy	59
No consolidation without representation: Correspondence between neural and psychological representations in recent and remote memory	58
Mechanisms of memory under stress	58
Fast, cell-resolution, contiguous-wide two-photon imaging to reveal functional network architectures across multi-modal cortical areas	58
Hypothalamus-habenula potentiation encodes chronic stress experience and drives depression onset	58
Sleep Promotes Downward Firing Rate Homeostasis	58
Sub-second Dopamine and Serotonin Signaling in Human Striatum during Perceptual Decision-Making	58
Emergent Elements of Inspiratory Rhythmogenesis: Network Synchronization and Synchrony Propagation	57
Overexpressing low-density lipoprotein receptor reduces tau-associated neurodegeneration in relation to apoE-linked mechanisms	57
Signaling snapshots of a serotonin receptor activated by the prototypical psychedelic LSD	57
Hippocampal Network Reorganization Underlies the Formation of a Temporal Association Memory	57
Upgrading the Physiological Relevance of Human Brain Organoids	57
Encoding of 3D Head Orienting Movements in the Primary Visual Cortex	57
Social touch-like tactile stimulation activates a tachykinin 1-oxytocin pathway to promote social interactions	56
CellExplorer: A framework for visualizing and characterizing single neurons	56
Sensory Discrimination of Blood and Floral Nectar by Aedes aegypti Mosquitoes	56
Cortical Representations of Conspecific Sex Shape Social Behavior	56
Microbiota-brain interactions: Moving toward mechanisms in model organisms	56
Nucleocytoplasmic Proteomic Analysis Uncovers eRF1 and Nonsense-Mediated Decay as Modifiers of ALS/FTD C9orf72 Toxicity	56
What is the dynamical regime of cerebral cortex?	56
The Value of Beliefs	55
Two Forms of Knowledge Representations in the Human Brain	55
Neuronal mitochondria transport Pink1 mRNA via synaptojanin 2 to support local mitophagy	55
Circadian VIPergic Neurons of the Suprachiasmatic Nuclei Sculpt the Sleep-Wake Cycle	55
Wireless Programmable Recording and Stimulation of Deep Brain Activity in Freely Moving Humans	55
Head Movements Control the Activity of Primary Visual Cortex in a Luminance-Dependent Manner	55
Engineered AAVs for non-invasive gene delivery to rodent and non-human primate nervous systems	54
Brain microvasculature has a common topology with local differences in geometry that match metabolic load	54
A Plug-and-Latch Mechanism for Gating the Mechanosensitive Piezo Channel	54
A transient developmental increase in prefrontal activity alters network maturation and causes cognitive dysfunction in adult mice	54
Pathogenic Huntingtin Repeat Expansions in Patients with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis	54
Wireless Optogenetic Stimulation of Oxytocin Neurons in a Semi-natural Setup Dynamically Elevates Both Pro-social and Agonistic Behaviors	54
Soma-Targeted Imaging of Neural Circuits by Ribosome Tethering	54
Medial and orbital frontal cortex in decision-making and flexible behavior	54
Extracting the dynamics of behavior in sensory decision-making experiments	54
Spatial modulation of hippocampal activity in freely moving macaques	54
RhoA drives actin compaction to restrict axon regeneration and astrocyte reactivity after CNS injury	53
HepaCAM controls astrocyte self-organization and coupling	53
Tracking Calcium Dynamics and Immune Surveillance at the Choroid Plexus Blood-Cerebrospinal Fluid Interface	53
Nicotine inhibits the VTA-to-amygdala dopamine pathway to promote anxiety	53
Wnt-Dependent Oligodendroglial-Endothelial Interactions Regulate White Matter Vascularization and Attenuate Injury	53
The Temporal Association Cortex Plays a Key Role in Auditory-Driven Maternal Plasticity	53
Visceral Mechano-sensing Neurons Control Drosophila Feeding by Using Piezo as a Sensor	53
Tackling neurodegenerative diseases with genomic engineering: A new stem cell initiative from the NIH	53
Signature morpho-electric, transcriptomic, and dendritic properties of human layer 5 neocortical pyramidal neurons	52
Flexible rerouting of hippocampal replay sequences around changing barriers in the absence of global place field remapping	52
Cortical Observation by Synchronous Multifocal Optical Sampling Reveals Widespread Population Encoding of Actions	52
APP Family Regulates Neuronal Excitability and Synaptic Plasticity but Not Neuronal Survival	51
Muscarinic M1 Receptors Modulate Working Memory Performance and Activity via KCNQ Potassium Channels in the Primate Prefrontal Cortex	51
Dual-Color Single-Cell Imaging of the Suprachiasmatic Nucleus Reveals a Circadian Role in Network Synchrony	51
Sleep—A brain-state serving systems memory consolidation	51
Cell-type-specific nicotinic input disinhibits mouse barrel cortex during active sensing	51
Emergence of Neuronal Diversity during Vertebrate Brain Development	51
Synaptic correlates of associative fear memory in the lateral amygdala	51
Distinct roles of dorsal and ventral subthalamic neurons in action selection and cancellation	51
Optimal anticipatory control as a theory of motor preparation: A thalamo-cortical circuit model	51
Molecular signatures underlying neurofibrillary tangle susceptibility in Alzheimer’s disease	51
Decoding Cellular Mechanisms for Mechanosensory Discrimination	51
Parallel in vivo analysis of large-effect autism genes implicates cortical neurogenesis and estrogen in risk and resilience	50
Context-Dependent Sensory Processing across Primary and Secondary Somatosensory Cortex	50