Journal of Autoimmunity

Article	Citations
ATP-binding cassette G1 membrane transporter-mediated cholesterol efflux capacity influences coronary atherosclerosis and cardiovascular risk in Rheumatoid Arthritis	438
Janus kinase inhibition prevents autoimmune diabetes in LEW.1WR1 rats	168
Safety of biologic immunosuppressants in pregnant women with immune-mediated inflammatory diseases	155
Advances in SLE classification criteria	146
Striatin-3 is a human autoantigen but it is not associated with the S-phase G2 nuclear antigen (SG2NA) staining pattern	121
GILZ regulates type I interferon release and sequesters STAT1	119
The universal effects of low-dose interleukin-2 across 13 autoimmune diseases in a basket clinical trial	116
HNF4α, SP1 and c-myc are master regulators of CNS autoimmunity	113
Immunological and fibrotic profiling in the NOD.c3c4 murine model of autoimmune cholangitis	106
Ectopic CD4+ T cells in choroid plexus mediate neuropsychiatric lupus symptoms in mice via interferon-γ induced microglia activation	100
Autoimmune associated HLAs and T cell autoantigens exhibit common patterns across several autoimmune diseases	98
Autoreactivity to self-antigens LL37 and ADAMTSL5 influences the clinical response to risankizumab in psoriatic patients	84
Differences in innate immune cell populations distinguish autoimmune from herpesvirus-associated encephalitis	81
Editorial Board	80
Disease activity in patients with immune-mediated inflammatory diseases after SARS-CoV-2 vaccinations	62
Tfh cell-derived small extracellular vesicles exacerbate the severity of collagen-induced arthritis by enhancing B-cell responses	60
Global and regional epidemiology of psoriatic arthritis in patients with psoriasis: A comprehensive systematic analysis and modelling study	59
Lupus nephritis: new progress in diagnosis and treatment	58
Breach of tolerance versus burden of bile acids: Resolving the conundrum in the immunopathogenesis and natural history of primary biliary cholangitis	58
Editorial Board	57
Anti-annexin A4 antibody as a biomarker for desquamative interstitial pneumonia	57
LAT1 enables T cell activation under inflammatory conditions	56
Editorial Board	56
Editorial Board	51
Proinflammatory CD20+CD3+ T cells as a potential driver of macrophage reprogramming in rheumatoid arthritis	51

Identification of the central tolerance checkpoint for autoreactive proteinase 3+ B cells in human bone marrow	51
Deciphering Sjögren's disease: New insights and perspectives extend from advanced omics approaches and immunology	47
Targeting macrophages with phosphatidylserine-rich liposomes as a potential antigen-specific immunotherapy for type 1 diabetes	46
Whole blood transcriptome identifies interferon-regulated genes as key drivers in thrombotic primary antiphospholipid syndrome	44
Glycobiology of psoriasis: A review	43
Mitochondrial dysfunction is a potential key mechanism for atherosclerosis predisposition in patients with systemic lupus erythematosus	41
Interferon signatures fuel B cell hyperactivity and plasmablast expansion in systemic lupus erythematosus	41
Earlier vs. later time period of COVID-19 infection and emergent autoimmune signs, symptoms, and serologies	40
Cellular communication network factor 3 contributes to the pathological process of rheumatoid arthritis through promoting cell senescence and osteoclastogenesis in the joint	39
FAPI PET/CT for tracking disease trajectory in myositis-related interstitial lung disease	38
Autoantibodies against a subunit of mitochondrial respiratory chain complex I in inclusion body myositis	37
Free water in the hippocampal cingulum as a Radiomic biomarker for Identifying inflammatory neuropsychiatric Lupus: A cross-sectional case-control study	36
Post-translationally modified proteins bind and activate complement with implications for cellular uptake and autoantibody formation	36
Assessment of the 2023 ACR/EULAR antiphospholipid syndrome classification criteria in a Chinese cohort: Impact on clinical practice	36
Non-coding RNAs in immunoregulation and autoimmunity: Technological advances and critical limitations	36
The complement system and human autoimmune diseases	35
Sunscreen use associated with elevated prevalence of anti-nuclear antibodies in U.S. adults	35
Antigenic mimicry – The key to autoimmunity in immune privileged organs	35
Editorial Board	33
Clinical targeted treatment in Sjogren's disease: A systematic literature review for an evidence-based medicine approach	32
Autoimmune markers and vascular immune deposits in Finkelstein-Seidlmayer vasculitis: Systematic literature review	32
Editorial Board	31
Differential changes in the gut microbiota between extrinsic and intrinsic atopic dermatitis	31
Perinatal use of targeted synthetic DMARDs and maternal-neonatal outcomes in autoimmune disease: A population-based cohort study	30
Clinical utility of measuring CD4+ T follicular cells in patients with immune dysregulation	30
External and internal exposome as triggers of biological signalling in systemic sclerosis – A narrative synthesis	30
Proprotein convertase subtilisin/kexin type 9 (PCSK9) levels in primary antiphospholipid syndrome. The multicenter ATHERO-APS study	29
The role of gut flora-driven Th cell responses in preclinical rheumatoid arthritis	29
Familial patterns of alopecia areata: A systematic review and meta-analysis	28
Long-term efficacy and safety of colchicine and anti-IL-1 blockers in FMF: results from the Eurofever multicenter observational study	28
Renal and vascular outcomes in patients with isolated antiphospholipid syndrome nephropathy	27
Peripheral immune profiling highlights a dynamic role of low-density granulocytes in myasthenia gravis	26
Silencing of aryl hydrocarbon receptor repressor restrains Th17 cell immunity in autoimmune hepatitis	26
Impact of BNT162b2 mRNA anti-SARS-CoV-2 vaccine on interferon-alpha production by plasmacytoid dendritic cells and autoreactive T cells in patients with systemic lupus erythematosus: The COVALUS proje	26
Single-cell sequencing of the retina shows that LDHA regulates pathogenesis of autoimmune uveitis	26
The aryl hydrocarbon receptor in immune regulation and autoimmune pathogenesis	25
Antigen-specific immune reactions by expanded CD8+ T cell clones from HLA-B*27-positive patients with spondyloarthritis	25
LAMP3-mediated epithelial-mesenchymal transition promotes the invasion and excessive proliferation of fibroblast-like synoviocytes in rheumatoid arthritis	25
Autoantibodies in systemic lupus erythematosus: From immunopathology to therapeutic target	25
Modulation of PKM2 inhibits follicular helper T cell differentiation and ameliorates inflammation in lupus-prone mice	25
Distinct gene dysregulation patterns herald precision medicine potentiality in systemic lupus erythematosus	25
Pregnancy-related complications in systemic lupus erythematosus	25
Alternate splicing converts human CD137 from costimulatory to immunosuppressive function	24
Coronavirus disease 2019, vaccination against coronavirus and immunoglobulin A-mediated diseases: systematic literature review	24
Evaluation of the mycophenolate mofetil–rituximab combination in systemic sclerosis: a French retrospective multicenter study (MycRiSSc)	23
Altered lipid metabolism in synovial fibroblasts of individuals at risk of developing rheumatoid arthritis	23
T cell aging as a risk factor for autoimmunity	23
Functional metagenomic analysis reveals potential inflammatory triggers associated with genetic risk for autoimmune disease	23
Recent advances in cutaneous lupus	23
Does COVID-19 impact the prevalence of myositis specific antibodies in the Netherlands? A comparative nationwide study	23

Acquired susceptibility to autoimmune diseases in pediatric patients with Escherichia coli infection: A population-matched retrospective cohort study	22
Environmental exposures as risk factors for idiopathic inflammatory myopathies	22
Editorial Board	22
Temporal trajectories and DMARD therapy retention of rheumatoid arthritis patients with different autoimmune and inflammatory comorbidity profiles: a retrospective analysis	22
RNA-binding protein hnRNP UL1 binds κB sites to attenuate NF-κB-mediated inflammation	22
Autoantibodies against α-synuclein inhibit its aggregation and cytotoxicity	22
Pathophysiological effects of long COVID-19 (auto)antibodies on fertility	21
High T-cell response rate after COVID-19 vaccination in belimumab and rituximab recipients	21
Identifying the genetic association between systemic lupus erythematosus and the risk of autoimmune liver diseases	21
High-content multimodal analysis supports the IL-7/IL-7 receptor axis as a relevant therapeutic target in primary Sjögren's syndrome	21
Anti-DNA antibody-targeted D-peptide nanoparticles ameliorate lupus nephritis in MRL/lpr mice	21
Preliminary safety and efficacy of relmacabtagene autoleucel (relma-cel) in adults with moderately to severely active systemic lupus erythematosus: a phase I dose-escalation study	21
T follicular helper cells in autoimmune diseases	20
JAK inhibitors in refractory juvenile rheumatic diseases: Efficacy, tolerance and type-I interferon profiling, a single center retrospective study	20
Interleukin 17-producing C-C motif chemokine receptor 6 + conventional CD4+ T cells are arthritogenic in an animal model of spondyloarthritis	20
2023 International Consensus Guidance for the use of Tripterygium Wilfordii Hook F in the treatment of active rheumatoid arthritis	20
Extracellular vesicle autoantibodies	20
Pro-fibrotic effect of the susceptible gene PCSK5 in vascular fibrosis of Takayasu arteritis via TGF-β and SMAD3 signaling pathway activation	20
Methotrexate and low-dose prednisone in idiopathic retroperitoneal fibrosis: a randomised clinical trial	20
Significance of anti-transcobalamin receptor antibodies in cutaneous arteritis revealed by proteome-wide autoantibody screening	20
Suppression of YTHDF2 attenuates autoimmune hepatitis by expansion of myeloid-derived suppressor cells	19
Immunosuppression induces regression of fibrosis in primary biliary cholangitis with moderate-to-severe interface hepatitis	19
Application of laboratory models for sarcoidosis research	19
Gut microbiota in systemic lupus erythematosus: A fuse and a solution	19
Altered glucose metabolism in B cells: Implications for the pathogenesis and treatment of autoimmune diseases	19
Interleukin-15 is a hair follicle immune privilege guardian	19
A survey of ficolin-3 activity in Systemic Lupus Erythematosus reveals a link to hematological disease manifestations and autoantibody profile	19
Pin1 maintains the effector program of pathogenic Th17 cells in autoimmune neuroinflammation	19
Comprehensive description of adult-onset Still's disease after COVID-19 vaccination	19
Editorial Board	18
Autoimmune diseases and the risk of bladder cancer: A Mendelian randomization analysis	18
VEXAS syndrome: A newly identified X-Linked hematoinflammatory disorder – A comprehensive overview of its genetic, molecular, inflammatory, and clinical landscape	18
CD72-semaphorin3A axis: A new regulatory pathway in systemic lupus erythematosus	18
Multi-omics study reveals different pathogenesis of the generation of skin lesions in SLE and IDLE patients	18
Acute-type acquired hemophilia A after COVID-19 mRNA vaccine administration: A new disease entity?	18
Natural IgG protects against early dissemination of vesicular stomatitis virus	18
Physical work demands and risk of rheumatoid arthritis, systemic sclerosis, and systemic lupus erythematosus. A Danish longitudinal cohort study	18
Association between age groups and relapse of type 1 autoimmune pancreatitis: a large-scale retrospective cohort study	18
Fecal microbiota transplantation in the treatment of systemic lupus erythematosus: What we learnt from the explorative clinical trial	18
Genetic and pharmacological targeting of GSDMD ameliorates systemic inflammation in macrophage activation syndrome	18
Regulatory T cells effectively downregulate the autoimmune anti-MPO response and ameliorate anti-MPO induced glomerulonephritis in mice	17
Cytokine producing B-cells and their capability to polarize macrophages in giant cell arteritis	17
Elevated unphosphorylated STAT1 and IRF9 in T and B cells of primary sjögren's syndrome: Novel biomarkers for disease activity and subsets	17
Neutrophil activation biomarker pentraxin 3 for diagnosis and monitoring of macrophage activation syndrome occurrence in adult-onset Still's disease	17
Cognitive dysfunction in SLE: An understudied clinical manifestation	17
Vascular effects of achieving low disease activity in axial spondyloarthritis – A 2-year prospective treat-to-target study	17
Amelioration of immunoglobulin A vasculitis by suppression of the pathological expansion of T follicular helper 17 cells	17
PD-1 antibody interactions with Fc gamma receptors enable PD-1 agonism to inhibit T cell activation – therapeutic implications for autoimmunity	16
Chimeric antigen receptor T cell therapy: a new frontier therapeutic landscape in autoimmune diseases	16
Repeated immunization with ATRA-containing liposomal adjuvant transdifferentiates Th17 cells to a Tr1-like phenotype	16
PD1+ innate lymphoid cells 3 predict JAK-dependent inflammation in rheumatoid arthritis	16
Accelerated waning of immune responses to a third COVID-19 vaccination in patients with immune-mediated inflammatory diseases	16
Poorer survival for patients with inflammatory arthritis treated with immune checkpoint inhibitors for melanoma	16
Developmental drugs for sarcoidosis	16
Treatment of mixed connective tissue disease: A multicenter retrospective study	16
The double-edged sword role of copper in rheumatoid arthritis: Mechanisms, therapeutics, and challenges	15
A cluster of type II interferon-regulated genes associates with disease activity in patients with systemic lupus erythematosus	15
Comparative effectiveness of preventive treatment with dimethyl fumarate-loaded solid lipid nanoparticles and oral dimethyl fumarate in a mouse model of multiple sclerosis	15
Extracellular microRNAs induce dendritic cell-dependent joint inflammation and potentiate osteoclast differentiation via TLR7/8 engagement	15
Pre-existing conditions associated with post-acute sequelae of COVID-19	15
Monoclonal antibodies from B cells of patients with anti-MDA5 antibody-positive dermatomyositis directly stimulate interferon gamma production	15
Autoimmune hepatitis following COVID-19 vaccination	15
Elderly-onset systemic sclerosis defines a distinct clinical subset: analysis from the SPRING registry of the Italian Society for Rheumatology	15
PPARG-mediated autophagy activation alleviates inflammation in rheumatoid arthritis	15
Outcome and prognosis of isolated carotid vasculitis	15
Autophagy pathways in autoimmune diseases	15
Sonic hedgehog promotes synovial inflammation and articular damage through p38 mitogen-activated protein kinase signaling in experimental arthritis	15
Beyond screening for pulmonary arterial hypertension: The DETECT score is a potential promising prediction tool for all-cause mortality in systemic sclerosis: Analysis from the EUSTAR database	14
B cell-specific mAb–siRNA conjugates improve experimental myasthenia	14
Peripheral helper T cells in human diseases	14
Editorial Board	14
Interpretation of the association between thyroid peroxidase antibodies and thyroid function during pregnancy: An individual participant data meta-analysis	14
What's in a name? – juxtaposing T follicular, peripheral and resident helper cells in B cell-driven autoimmune diseases	14
Pathogenicity of functionally activated PD-1+CD8+ cells and counterattacks by muscular PD-L1 through IFNγ in myositis	14
Loss of function of XBP1 splicing activity of IRE1α favors B cell tolerance breakdown	14
Modulating T-cell activation with antisense oligonucleotides targeting lymphocyte cytosolic protein 2	14
Immune-mediated necrotizing myopathy: A comprehensive review of the pathogenesis, clinical features, and treatments	14
Trained innate immunity in response to nuclear antigens in systemic lupus erythematosus	13
Diversity and function of regulatory T cells in health and autoimmune diseases	13
Anti-retinal immune response in sarcoid uveitis: A potential role for PCLO as an antigenic target	13

Autoreactive T cells targeting type II pneumocyte antigens in COVID-19 convalescent patients	13
Sera from patients with dermatomyositis and antisynthetase syndrome mediate muscle weakness, impair mitochondrial respiration and induce local cytokine production in muscle tissue	13
Flagellin-specific human CAR Tregs for immune regulation in IBD	13
Cytokine receptor γc effectuates the generation of proinflammatory innate CD8 T cells by non-classical MHC-I molecules	13
Editorial Board	13
mTOR-dependent loss of PON1 secretion and antiphospholipid autoantibody production underlie autoimmunity-mediated cirrhosis in transaldolase deficiency	13
Risk factors for hypogammaglobulinemia and association with relapse and severe infections in ANCA-associated vasculitis: A cohort study	13
Prioritization of infectious epitopes for translational investigation in type 1 diabetes etiology	13
High throughput screening identifies repurposable drugs for modulation of innate and acquired immune responses	12
Transcriptomic analyses of lung tissues reveal key genes associated with progression of systemic sclerosis-interstitial lung disease (SSc-ILD)	12
How early-life adversity affects the risk of pediatric-onset immune-mediated inflammatory disease	12
Immune complexome analysis of a rich variety of serum immune complexes identifies disease-characteristic immune complex antigens in systemic sclerosis	12
Melatonin synergistically potentiates the effect of methylprednisolone on reducing neuroinflammation in the experimental autoimmune encephalomyelitis mouse model of multiple sclerosis	12
Novel and unique rheumatoid factors cross-react with viral epitopes in COVID-19	12
Editorial Board	12
SARS-CoV-2 mRNA vaccines do not worsen autoimmunity in patients with autoimmune liver diseases	12
Treatment outcomes stratified by interferon profile and autoantibodies in rheumatoid arthritis	12
Editorial Board	12
Autoimmune modulation of immune-endocrine-metabolic regulation of ovarian reserve: A cohort study of 803 women	12
Gut microbiome, metabolome, host immunity associated with inflammatory bowel disease and intervention of fecal microbiota transplantation	12
Sex differences in biomarkers and biologic mechanisms in psoriatic diseases and spondyloarthritis	12
TIGIT-Fc fusion protein alleviates murine lupus nephritis through the regulation of SPI-B-PAX5-XBP1 axis-mediated B-cell differentiation	12
K2P2.1 is a regulator of inflammatory cell responses in idiopathic inflammatory myopathies	12
Mepolizumab versus benralizumab for eosinophilic granulomatosis with polyangiitis (EGPA): A European real-life retrospective comparative study	12
Blockade of neutrophil extracellular trap components ameliorates cholestatic liver disease in Mdr2 (Abcb4) knockout mice	12
Autoantibodies against the NineTeen complex and U5 RNP in systemic sclerosis	12
WTAP promotes the progression of ulcerative colitis by silencing the expression of CES2 through m6A modification	11
The risk of cancer in pediatric-onset immune-mediated inflammatory diseases – A nationwide study	11
COVID-19 outcomes in giant cell arteritis and polymyalgia rheumatica versus rheumatoid arthritis: A national, multicenter, cohort study	11
Control of naive and effector CD4 T cell receptor repertoires by rheumatoid-arthritis-risk HLA alleles	11
Perivascular B cells link intestinal angiogenesis to immunity and to the gut-brain axis during neuroinflammation	11
Targeted protein degradation in autoimmune diseases: from mechanisms to therapeutic breakthroughs	11
Passive maternal immunity in children born to women with systemic autoimmune rheumatic disease – A case-control study	11
SARS-CoV-2 vaccination and risk of severe COVID-19 outcomes in patients with autoimmune hepatitis	11
Phosphatase control of cytokine-mediated overproduction of galactose-deficient IgA1, the main autoantigen in IgA nephropathy	11
Evolving understandings for the roles of non-coding RNAs in autoimmunity and autoimmune disease	11
Compositional and functional aberrance of the gut microbiota in treatment-naïve patients with primary Sjögren's syndrome	11
Alopecia Areata: Case report and review of pathophysiology and treatment with Jak inhibitors	11
Effects of fecal microbiota transplant on DNA methylation in patients with systemic lupus erythematosus	11
ETS-1 facilitates Th1 cell-mediated mucosal inflammation in inflammatory bowel diseases through upregulating CIRBP	10
Butyrophilin 2a2 (Btn2a2) expression on thymic epithelial cells promotes central T cell tolerance and prevents autoimmune disease	10
Cognition following chimeric antigen receptor T-cell therapy: A systematic review	10
Salivary gland epithelial cell in Sjögren's syndrome: Metabolic shift and altered mitochondrial morphology toward an innate immune cell function	10
Multiple sclerosis-associated EBNA2 variants influence the response to peginterferon beta-1a therapy	10
Neutrophil-derived extracellular vesicles induce endothelial inflammation and damage through the transfer of miRNAs	10
Signal responses to neutral TSH receptor antibody – A cycle of damage in the pathophysiology of Graves’ disease	10
CD72 is an inhibitory pattern recognition receptor that recognizes ribosomes and suppresses production of anti-ribosome autoantibody	10
Evaluation of minor labial salivary gland focus score in Sjögren's disease using deep learning: a tool for more efficient diagnosis and future tissue biomarker discovery	10
The concept of severity in psoriatic arthritis: a scoping review of the literature	10
Circulating T cells in sarcoidosis have an aberrantly activated phenotype that correlates with disease outcome	10
Neointimal myofibroblasts contribute to maintaining Th1/Tc1 and Th17/Tc17 inflammation in giant cell arteritis	10
SB431542 alleviates lupus nephritis by regulating B cells and inhibiting the TLR9/TGFβ1/PDGFB signaling	10
Tlr9 expression protects against Tlr7-dependent exocrine gland and systemic disease manifestations in primary Sjögren's disease in a sex-biased manner	10
Conformational state of C-reactive protein is critical for reducing immune complex-triggered type I interferon response: Implications for pathogenic mechanisms in autoimmune diseases imprinted by type	10
Supraphysiological FOXP3 expression in human CAR-Tregs results in improved stability, efficacy, and safety of CAR-Treg products for clinical application	10
Identification of a novel PDC-E2 epitope in primary biliary cholangitis: Application for engineered Treg therapy	10
miR-143-3p boosts extracellular vesicles to improve the dermal fibrosis of localized scleroderma	10
Molecular signature of neutrophil extracellular trap mediating disease module in idiopathic inflammatory myopathy	10
Isolation and characterisation of PR3-specific B cells and their immunoglobulin sequences	9
Caspase-10 affects the pathogenesis of primary biliary cholangitis by regulating inflammatory cell death	9
Divergent regulatory T cell responses to high-dose methylprednisolone and tocilizumab in giant cell arteritis	9
Increased RNA editing sites revealed as potential novel biomarkers for diagnosis in primary Sjögren's syndrome	9
Involvement of trained immunity during autoimmune responses	9
Soluble form of immune checkpoints in autoimmune diseases	9
Sarcoidosis and its relation to other immune-mediated diseases: Epidemiological insights	9
Circulating immune profile in granulomatosis with polyangiitis reveals distinct patterns related to disease activity	9
Interventional studies targeting the prodromal or preclinical phase of immune-mediated disease to benefit patient outcomes: a scoping review	9
Editorial Board	9
Editorial Board	9
Neuropsychiatric lupus erythematosus: Focusing on autoantibodies	9
Single-cell analysis highlights a population of Th17-polarized CD4+ naïve T cells showing IL6/JAK3/STAT3 activation in pediatric severe aplastic anemia	9
Vasculopathy and vasculitis associated with levamisole-adulterated cocaine: a systematic review	9
Fecal microbiota transplantation for the management of autoimmune diseases: Potential mechanisms and challenges	9
The emerging role of BLyS/APRIL in autoimmune diseases: Biological characteristics, functions, and therapeutic potential	9
Advanced pulmonary sarcoidosis	9
Old known and possible new biomarkers of ANCA-associated vasculitis	9
A framework for exclusion of alternative diagnoses in sarcoidosis	9
Renoprotective anti-CD45RB antibody induces B cell production in systemic lupus erythematosus based on single-cell RNA-seq analysis	9
Associations between domestic hard water exposure and incident psoriasis in adults: Insights from the UK Biobank cohort study	9
A novel subset of inflammation-related liver NK cells modulates immune responses in a murine model of primary biliary cholangitis	9
Inflammatory disease status and response to TNF blockade are associated with mechanisms of endotoxin tolerance	9
The immunomodulatory roles of the gut microbiome in autoimmune diseases of the central nervous system: Multiple sclerosis as a model	8
Role of mitochondria in the myopathy of juvenile dermatomyositis and implications for skeletal muscle calcinosis	8
LIGHT signaling through LTβR and HVEM in keratinocytes promotes psoriasis and atopic dermatitis-like skin inflammation	8
Editorial Board	8
Integrative single-cell analysis reveals distinct adaptive immune signatures in the cutaneous lesions of pemphigus	8
Lung transplantation in pulmonary sarcoidosis	8
Tissue-resident memory T cells: The key frontier in local synovitis memory of rheumatoid arthritis	8
Exercise, autoimmune diseases and T-regulatory cells	8
Editorial Board	8
Calprotectin and neurofilament serum levels correlate with treatment response in myasthenia gravis under intensified therapy–A pilot study	8
Prior murine neurotropic coronavirus infection ameliorates experimental autoimmune encephalitis	8
Autoreactive B cells remain active despite clinical disease control in rheumatoid arthritis	8
Infectious diseases, autoantibodies, and autoimmunity	8
Gut dysbiosis promotes islet-autoimmunity by increasing T-cell attraction in islets via CXCL10 chemokine	8