Cellular Signalling

Papers
(The TQCC of Cellular Signalling is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)
ArticleCitations
Role of moesin and its phosphorylation in VE-cadherin expression and distribution in endothelial adherens junctions119
Phosphorylation of mammalian mitochondrial EF-Tu by Fyn and c-Src kinases111
LncRNA Malat1 regulates iPSC-derived β-cell differentiation by targeting the miR-15b-5p/Ihh axis92
A novel role of ADAMTS16 in renal fibrosis through activating TGF-β/Smad signaling74
pVHL promotes lysosomal degradation of YAP in lung adenocarcinoma71
Methylation and transcriptome analyses construct a prognostic model and reveal the suppressor role of VMO1 in lung adenocarcinoma66
Genome-scale CRISPR-Cas9 screening stratifies pancreatic cancer with distinct outcomes and immunotherapeutic efficacy65
TSG101 overexpression enhances metastasis in oral squamous cell carcinoma through cell cycle regulation63
Editorial Board62
Exploring m6A methylation in skin Cancer: Insights into molecular mechanisms and treatment62
Editorial Board58
Effect of fibroblasts small- conductance Ca2+ -activated potassium channel subtype 2 (SK2) on myocardial fibrosis in pressure overload mouse56
Central repeat fragment of reelin leads to active reelin intracellular signaling and rescues cognitive deficits in a mouse model of reelin deficiency53
Comprehensive split TEV based protein-protein interaction screening reveals TAOK2 as a key modulator of Hippo signalling to limit growth52
ArfGAP3 regulates vesicle transport and glucose uptake in myoblasts49
Oncolytic HSV-1 suppresses cell invasion through downregulating Sp1 in experimental glioblastoma45
Rigosertib elicits potent anti-tumor responses in colorectal cancer by inhibiting Ras signaling pathway45
DSCR1–1 attenuates osteoarthritis-associated chondrocyte injury by regulating the CREB1/ALDH2/Wnt/β-catenin axis: An in vitro and in vivo study44
Nuak kinase signaling in development and disease of the central nervous system44
Paricalcitol attenuates oxidative stress and inflammatory response in the liver of NAFLD rats by regulating FOXO3a and NFκB acetylation43
Iron overload induces apoptosis of osteoblast cells via eliciting ER stress-mediated mitochondrial dysfunction and p-eIF2α/ATF4/CHOP pathway in vitro43
E3 ubiquitin ligase CHIP interacts with transferrin receptor 1 for degradation and promotes cell proliferation through inhibiting ferroptosis in hepatocellular carcinoma40
Activating transcription factor 6 protects against endothelial barrier dysfunction39
The main molecular mechanisms of ferroptosis and its role in chronic kidney disease37
The role of microRNA-induced apoptosis in diverse radioresistant cancers37
DUSP2 affects bladder cancer prognosis by down-regulating MEK/ERK and P38 MAPK signaling pathways through PTPN735
Hypoxia and ferroptosis34
GALNT3 protects against phosphate-induced calcification in vascular smooth muscle cells by enhancing active FGF23 and inhibiting the wnt/β-catenin signaling pathway33
S100P facilitates LUAD progression via PKA/c-Jun-mediated tumor-associated macrophage recruitment and polarization33
METTL3 promotes the growth and metastasis of pancreatic cancer by regulating the m6A modification and stability of E2F533
Mechanical stress induced EndoMT in endothelial cells through PPARγ downregulation32
Role of ceramide/sphingomyelin (SM) balance regulated through “SM cycle” in cancer32
POSTN promotes diabetic vascular calcification by interfering with autophagic flux32
Uptake of ox-LDL by binding to LRP6 mediates oxidative stress-induced BMSCs senescence promoting obesity-related bone loss32
Backstage players of fibrosis: NOX4, mTOR, HDAC, and S1P; companions of TGF-β32
The renin-angiotensin-aldosterone system: An old tree sprouts new shoots31
HOXA1 promotes aerobic glycolysis and cancer progression in cervical cancer31
hMOB2 deficiency impairs homologous recombination-mediated DNA repair and sensitises cancer cells to PARP inhibitors30
Potential role of Hematopoietic PBX-Interacting Protein (HPIP) in trophoblast fusion and invasion: Implications in pre-eclampsia pathogenesis30
Activation of SIRT3 by Tanshinone IIA ameliorates renal fibrosis by suppressing the TGF-β/TSP-1 pathway and attenuating oxidative stress30
Identification of resident progenitors labeled with Top2a responsible for proximal tubular regeneration in ischemia reperfusion-induced acute kidney injury30
Verbenalin alleviates acute lung injury induced by sepsis and IgG immune complex through GPR18 receptor30
B-cell receptor signaling induces proteasomal degradation of PDCD4 via MEK1/2 and mTORC1 in malignant B cells30
CircRNA0007766 accelerates cancer progression via miR-34c-5p/cyclin D1 axis in adenocarcinoma of the esophagogastric junction (AEG)30
HOXD9 transcriptionally induced UXT facilitate breast cancer progression via epigenetic modification of RND329
MAP kinases in regulation of NOX activity stimulated through two types of formyl peptide receptors in murine bone marrow granulocytes29
Rescue of synaptosomal glutamate release defects in tau transgenic mice by the tau aggregation inhibitor hydromethylthionine29
SphK1 deficiency ameliorates the development of atherosclerosis by inhibiting the S1P/S1PR3/Rhoa/ROCK pathway29
MSTN gene knockout suppresses the activation of lung fibroblasts through the inhibition of the Smad/AKT signaling pathway, thereby ameliorating pulmonary fibrosis28
C-MYC induces idiopathic pulmonary fibrosis via modulation of miR-9-5p-mediated TBPL128
ACVR1 mediates renal tubular EMT in kidney fibrosis via AKT activation28
Sustained systemic inflammation increases autophagy and induces EMT/fibrotic changes in mouse liver cells: Protection by melatonin28
Hsa_circ_0048764 facilitates the progression of non-small cell lung cancer by targeting miR-1178-3p/HMGA1 axis28
G protein-coupled receptor kinase type 2 and β-arrestin2: Key players in immune cell functions and inflammation28
Compartmentalized cAMP signaling in cardiac ventricular myocytes27
Understanding the impact of nuclear-localized GPCRs on cellular signalling27
Cardiomyocyte PAI-1 influences the cardiac transcriptome and limits the extent of cardiac fibrosis in response to left ventricular pressure overload27
HKDC1 promotes autophagy and proliferation in pancreatic adenocarcinoma through interaction with PARP1 and poly(ADP-ribosyl)ation27
The interplay between estrogen receptor beta and protein kinase C, a crucial collaboration for medulloblastoma cell proliferation and invasion27
Low-intensity pulsed ultrasound (LIPUS) promotes skeletal muscle regeneration by regulating PGC-1α/AMPK/GLUT4 pathways in satellite cells/myoblasts26
RETRACTED: Exploring the role of astrocytic dysfunction and AQP4 in depression25
Hsa_circ_0136666 activates Treg-mediated immune escape of colorectal cancer via miR-497/PD-L1 pathway24
Irisin improves BBB dysfunction in SAP rats by inhibiting MMP-9 via the ERK/NF-κB signaling pathway24
Retraction notice to “Exploring the role of biologics in depression” [Cellular Signalling 98 (2022) 110409]24
NQO1 alleviates renal fibrosis by inhibiting the TLR4/NF-κB and TGF-β/Smad signaling pathways in diabetic nephropathy24
NOX4 alleviates breast cancer cell aggressiveness by co-ordinating mitochondrial turnover through PGC1α/Drp1 axis24
Zika virus NS1 suppresses VE-cadherin via hsa-miR-29b-3p/DNMT3b/MMP-9 pathway in human brain microvascular endothelial cells24
Phosphodiesterase-1 in the cardiovascular system24
Promoting the proliferation of osteoarthritis chondrocytes by resolvin D1 regulating the NLRP3/caspase-1 signaling pathway24
PDGFRB promotes dedifferentiation and pulmonary metastasis through rearrangement of cytoskeleton under hypoxic microenvironment in osteosarcoma23
STEAP4 modulates cell proliferation and oxidative stress in benign prostatic hyperplasia23
METTL3-mediated m6A RNA modification promotes corneal neovascularization by upregulating the canonical Wnt pathway during HSV-1 infection23
Isoimperatorin down-regulates epithelial mesenchymal transition through modulating NF-κB signaling and CXCR4 expression in colorectal and hepatocellular carcinoma cells23
CHD4 mediates SOX2 transcription through TRPS1 in luminal breast cancer23
The signaling pathways activated by ROR1 in cancer23
Exosomal B7-H3 facilitates colorectal cancer angiogenesis and metastasis through AKT1/mTOR/VEGFA pathway23
CPT2-mediated fatty acid oxidation inhibits tumorigenesis and enhances sorafenib sensitivity via the ROS/PPARγ/NF-κB pathway in clear cell renal cell carcinoma23
Boldine prevents the inflammatory response of cardiac fibroblasts induced by SGK1-NFκB signaling pathway activation22
Fangchinoline inhibits metastasis and reduces inflammation-induced epithelial-mesenchymal transition by targeting the FOXM1-ADAM17 axis in hepatocellular carcinoma22
SARS-CoV-2 NSP16 promotes IL-6 production by regulating the stabilization of HIF-1α22
Unraveling the role of the renin-angiotensin system in severe mental illnesses: An insight into psychopathology and cognitive deficits22
Glucagon transiently stimulates mTORC1 by activation of an EPAC/Rap1 signaling axis22
SIRT3 deficiency exacerbates early-stage fibrosis after ischaemia-reperfusion-induced AKI22
RelB promotes the migration and invasion of prostate cancer DU145 cells via exosomal ICAM1 in vitro22
LINC00426, a novel m6A-regulated long non-coding RNA, induces EMT in cervical cancer by binding to ZEB122
Substrate stiffness modulates osteogenic and adipogenic differentiation of osteosarcoma through PIEZO1 mediated signaling pathway21
Inhibition of ubiquitin-specific protease 7 ameliorates ferroptosis-mediated myocardial infarction by contrasting oxidative stress: An in vitro and in vivo analysis21
Human placental mesenchymal stromal cells alleviate intestinal oxidative damage in mice with graft-versus-host disease via CD73/adenosine/PI3K/Akt/GSK-3β axis21
Aquaporin-5 facilitates liver regeneration following hepatectomy via ROS/GSDMD pathway21
FGD5-AS1/miR-5590-3p/PINK1 induces Lenvatinib resistance in hepatocellular carcinoma21
Circ-AMOTL1 enhances cardiac fibrosis through binding with EIF4A3 and stabilizing MARCKS expression in diabetic cardiomyopathy21
Epicatechin protects mice against OVA-induced asthma through inhibiting airway inflammation and modulating gut microbiota21
The roles of IDH2 and glutathione metabolism in cetuximab resistance in head and neck squamous cell carcinoma investigated by metabolomics and transcriptomics21
Controlling BMP growth factor bioavailability: The extracellular matrix as multi skilled platform20
An update on the molecular mechanism and pharmacological interventions for Ischemia-reperfusion injury by regulating AMPK/mTOR signaling pathway in autophagy20
The major vault protein integrates adhesion-driven signals to regulate collagen remodeling19
Lactate dehydrogenase B as a metabolism-related marker for immunotherapy in head and neck squamous cell carcinoma19
Pharmacological inhibition of SREBP1 suppresses pancreatic cancer growth via inducing GPX4-mediated ferroptosis19
Editorial Board19
Vav1 accelerates Ras-driven lung cancer and modulates its tumor microenvironment.19
A computational biology approach to identify potential protein biomarkers and drug targets for sporadic amyotrophic lateral sclerosis19
ADAMTS12 promotes oxaliplatin chemoresistance and angiogenesis in gastric cancer through VEGF upregulation18
Small extracellular vesicles from HO-1-modified bone marrow-derived mesenchymal stem cells attenuate ischemia-reperfusion injury after steatotic liver transplantation by suppressing ferroptosis via mi18
Study on the effects and mechanism of RRM2 on three gynecological malignancies18
Functional delineation of the luminal epithelial microenvironment in breast using cell-based screening in combinatorial microenvironments18
A comprehensive evaluation of circ_0065214/ miR-188-3p/GPNMB axis in breast cancer18
Histone H4K12 lactylation promotes malignancy progression in triple-negative breast cancer through SLFN5 downregulation18
Prolyl isomerase Pin1 promotes autophagy and cancer cell viability through activating FoxO3 signalling18
Corrigendum to “TET1 mediated m5C modification of RelB aggravates cerebral ischemia/reperfusion-induced neuroinflammation through regulating microglia polarization” [Cell Signal. 2024 Aug;120:111210]18
Circular RNA circZFPM2 promotes epithelial-mesenchymal transition in endometriosis by regulating miR-205-5p/ZEB1 signalling pathway18
mTOR potentiates senescent phenotypes and primary cilia formation after cisplatin-induced G2 arrest in retinal pigment epithelial cells18
miR-425-5p as an exosomal biomarker for metastatic prostate cancer18
AMPK-mediated autophagy pathway activation promotes ΔFosB degradation to improve levodopa-induced dyskinesia18
The emerging role of PANoptosis in viral infections disease18
DEAD-box protein 21 promotes renal fibrosis via p21-dependent cell cycle arrest in proximal tubular epithelial cells18
6-methylcoumarin/miR-122 suppresses hepatic Sortilin-mediated ApoB-100 secretion to attenuate aortic atherosclerosis18
RIPK4 downregulation impairs Wnt3A-stimulated invasiveness via Wnt/β-catenin signaling in melanoma cells and tumor growth in vivo18
METTL14-mediated N6-methyladenosine modification of TCP1 mRNA promotes acute myeloid leukemia progression17
Immunogenicity of cancer cells: An overview17
CircINADL promotes nasopharyngeal carcinoma metastasis by inhibiting HuR ubiquitin degradation and disrupting the hippo signaling pathway17
Cardiac fibrosis: Pathobiology and therapeutic targets17
Unraveling the molecular crosstalk and immune landscape between COVID-19 infections and ischemic heart failure comorbidity: New insights into diagnostic biomarkers and therapeutic approaches17
TAGLN2 targeted control of ARPC5-mediated activation of the MEK/ERK signaling pathway influences the proliferation, invasion, and metastasis of pancreatic cancer cells17
Corrigendum to “Numb/Notch/PLK1 signaling pathway mediated hyperglycemic memory in pancreatic cancer cell radioresistance and the therapeutic effects of metformin” [Cellular Signalling 93 (2022) 1102617
Hsa_circ_0000851 promotes PDK1/p-AKT-mediated cell proliferation and migration by regulating miR-1183 in triple-negative breast cancer17
Regulatory effects of HIF-1α and HO-1 in hypoxia-induced proliferation of pulmonary arterial smooth muscle cells in yak17
IL-10 inhibits osteoclast differentiation and osteolysis through MEG3/IRF8 pathway17
PacBio full-length transcriptome analysis reveals the role of tRNA-like structures in RNA processing17
Editorial Board17
Inhibition of Let-7b-5p maturation by LIN28A promotes thermal skin damage repair after burn injury17
miR-15a-5p enhances the malignant phenotypes of colorectal cancer cells through the STAT3/TWIST1 and PTEN/AKT signaling pathways by targeting SIRT417
MicroRNA-30c-5p arrests bladder cancer G2/M phase and suppresses its progression by targeting PRC1-mediated blocking of CDK1/Cyclin B1 axis17
Deciphering the relationship between caveolae-mediated intracellular transport and signalling events17
Corrigendum to “The Bmi-1 helix-turn and ring finger domains are required for Bmi-1 antagonism of (−) epigallocatechin-3-gallate suppression of skin cancer cell survival” [Cell Signaling 27 (2015) 13317
G3bp1 – microRNA-1 axis regulates cardiomyocyte hypertrophy17
Overexpression of Dermokine-α enhances the proliferation and epithelial-mesenchymal transition of pancreatic tumor cells17
TRIM33 enhances the ubiquitination of TFRC to enhance the susceptibility of liver cancer cells to ferroptosis16
Non-cyclic nucleotide EPAC1 activators suppress lipopolysaccharide-regulated gene expression, signalling and intracellular communication in differentiated macrophage-like THP-1 cells16
Development of stemness-related signature to optimize prognosis prediction and identify XMD8-85 as a novel therapeutic compound for glioma16
Identification and validation of ferroptosis-related genes for diabetic retinopathy16
Lung cancer associated transcript 1 binds heat shock protein 90 to promote growth of hepatocellular carcinoma16
MTFR2 accelerates hepatocellular carcinoma mediated by metabolic reprogramming via the Akt signaling pathway16
Hsa-miR-34a-5p reverses multidrug resistance in gastric cancer cells by targeting the 3′-UTR of SIRT1 and inhibiting its expression16
Cancer-associated fibroblasts-induced remodeling of tumor immune microenvironment via Jagged1 in glioma16
Mammalian cleavage factor 25 targets KLF14 to inhibit hepatic stellate cell activation and liver fibrosis16
Reduced YAP1 and FOLR1 in gliomas predict better response to chemotherapeutics16
Deficiency of ATF2 retards senescence induced by replication stress and pamidronate in mouse jaw bone marrow stem cells15
Mechanism of neutrophil extracellular traps generation and their role in trophoblasts apoptosis in gestational diabetes mellitus15
Transcriptome sequencing analysis reveals miR-30c-5p promotes ferroptosis in cervical cancer and inhibits growth and metastasis of cervical cancer xenografts by targeting the METTL3/KRAS axis15
Neutrophil extracellular traps promote gastric cancer cell metastasis via the NAT10-mediated N4-acetylcytidine modification of SMYD215
DDX24 promotes tumor progression by mediating hexokinase-1 induced glycolysis in gastric cancer15
Glutamatergic transmission and receptor expression in the synucleinopathy h-α-synL62 mouse model: Effects of hydromethylthionine15
Corrigendum to “Iron depletion suppresses mTORC1-directed signalling in intestinal Caco-2 cells via induction of REDD1” [Cellular Signalling, 28: (2016) 412–424]15
Visfatin-induced upregulation of lipogenesis via EGFR/AKT/GSK3β pathway promotes breast cancer cell growth15
CTCF modulates adipocyte lipolysis via directly regulating the expression of Beclin 1 with the cooperation of PPARγ15
Non-coding RNAs as mediators of epithelial to mesenchymal transition in metastatic colorectal cancers15
Macrophage-conditioned medium enhances tunneling nanotube formation in breast cancer cells via PKC, Src, NF-κB, and p38 MAPK signaling15
Unveiling the potential of proteomic and genetic signatures for precision therapeutics in lung cancer management15
Aerobic plus resistance exercise attenuates skeletal muscle atrophy induced by dexamethasone through the HDAC4/FoxO3a pathway15
Anthocyanins from blueberry ameliorated arsenic-induced memory impairment, oxidative stress, and mitochondrial-biosynthesis imbalance in rat hippocampal neurons15
Targeting epithelial cell-derived TWIST1 alleviates allergic asthma15
C1GALT1 high expression enhances the progression of glioblastoma through the EGFR-AKT/ERK cascade15
RETRACTED: Exploring the role of biologics in depression15
Metabolic crosstalk: Extracellular ATP and the tumor microenvironment in cancer progression and therapy15
Phosphorylated Hsp27 promotes adriamycin resistance in breast cancer cells through regulating dual phosphorylation of c-Myc14
The cytopathic activity of cholera toxin requires a threshold quantity of cytosolic toxin14
Hijacking of GPCRs and RTKs by pathogens14
An integrative pan-cancer analysis of WWC family genes and functional validation in lung cancer14
Activation of TGF-β - SMAD2 signaling by IL-6 drives neuroendocrine differentiation of prostate cancer through p38MAPK14
Editorial Board14
Ectopic viral integration Site-1 oncogene promotes NRAS pathway through epigenetic silencing of microRNA-124 in acute myeloid leukemia14
LncRNA HOXA11-AS intercepts the POU2F2-mediated downregulation of SLC3A2 in osteoarthritis to suppress ferroptosis14
Histone methyltransferase EZH2 epigenetically affects CCNA1 expression in acute myeloid leukemia14
Unveiling the bidirectional role of MMP9: A key player in kidney injury14
Tumor-suppressive role of miR-139-5p in angiogenesis and tumorigenesis of ovarian cancer: Based on GEO microarray analysis and experimental validation14
Circular RNA and human diseases: Basic research and translational implications14
Ferroptosis-related LINC02535/has-miR-30c-5p/EIF2S1 axis as a novel prognostic biomarker involved in immune infiltration and progression of PDAC14
Extracellular vesicle-induced cyclic AMP signaling14
STNM1 in human cancers: role, function and potential therapy sensitizer13
Decreased autophagy impairs osteogenic differentiation of adipose-derived stem cells via Notch signaling in diabetic osteoporosis mice13
Upregulation of miR-20b-5p inhibits trophoblast invasion by blocking autophagy in recurrent miscarriage13
FGF10 attenuates allergic airway inflammation in asthma by inhibiting PI3K/AKT/NF-κB pathway13
Cancer-associated fibroblasts promote oral squamous cell carcinoma progression by targeting ATP7A via exosome-mediated paracrine miR-148b-3p13
Wnt5a alleviates the symptoms of PCOS by modulating PI3K/AKT/mTOR pathway-mediated autophagy in granulosa cells13
Ferroptosis: The functions of Nrf2 in human embryonic stem cells13
SYK and ZAP70 kinases in autoimmunity and lymphoid malignancies13
Promoter A1312C mutation leads to microRNA-7 downregulation in human non-small cell lung cancer13
Brain-derived neurotrophic factor promotes orthodontic tooth movement by alleviating periodontal ligament stem cell senescence13
Visceral adipose tissue-directed human kallistatin gene therapy improves adipose tissue remodeling and metabolic health in obese mice13
Foxd3/SLC5A6 axis regulates apoptosis in LUAD cells by controlling mitochondrial biotin uptake13
Ewing sarcoma depends on C4orf48/NICOL, a NELL2 cofactor regulated by hippo signaling13
Glaucoma and the ocular renin-angiotensin-aldosterone system: Update on molecular signalling and treatment perspectives13
Reversion inducing cysteine rich protein with Kazal motifs and cardiovascular diseases: The RECKlessness of adverse remodeling13
MicroRNA sequence analysis of plasma exosomes in early Legg–Calvé–Perthes disease13
HDAC1 inhibits beige adipocyte-mediated thermogenesis through histone crotonylation of Pgc1a/Ucp113
Biased agonism at G protein-coupled receptors13
FOXC1 promotes EMT and colorectal cancer progression by attracting M2 macrophages via the TGF-β/Smad2/3/snail pathway13
LncRNA HOTAIR sponges miR-301a-3p to promote glioblastoma proliferation and invasion through upregulating FOSL113
The role of acetaldehyde dehydrogenase 2 in the pathogenesis of liver diseases13
FTO-dependent N(6)-Methyladenosine regulates the progression of endometriosis via the ATG5/PKM2 Axis13
LncRNA HMOX1 alleviates renal ischemia-reperfusion-induced ferroptotic injury via the miR-3587/HMOX1 axis13
Mitochondria as intracellular signalling organelles. An update13
Induction, amplification, and propagation of diabetic retinopathy-associated inflammatory cytokines between human retinal microvascular endothelial and Müller cells and in the mouse retina13
Editorial Board12
Silencing ESRP1 expression promotes caspase-independent cell death via nuclear translocation of AIF in colon cancer cells12
Artesunate-loaded solid lipid nanoparticles resist esophageal squamous cell carcinoma by inducing Ferroptosis through inhibiting the AKT/mTOR signaling12
Functions and therapeutic interventions of non-coding RNAs associated with TLR signaling pathway in atherosclerosis12
Activated PARP1/FAK/COL5A1 signaling facilitates the tumorigenesis of cholesterol-resistant ovarian cancer cells through promoting EMT12
Transmembrane protein TMEM97 and epigenetic reader BAHCC1 constitute an axis that supports pro-inflammatory cytokine expression12
Profile of 5-HT2A receptor involved in signaling cascades associated to intracellular inflammation and apoptosis in hepatocytes and its role in carbon tetrachloride-induced hepatotoxicity12
The MEF2A/SNHG16/miR-425-5p/NOTCH2 axis induces gemcitabine resistance by inhibiting ferroptosis in the starving bladder tumor microenvironment12
SEPT5 overexpression predicts poor prognosis and promotes progression through feedback regulation of HIF-1α in clear cell renal cell carcinoma12
The Warburg effect in osteoporosis: Cellular signaling and epigenetic regulation of energy metabolic events to targeting the osteocalcin for phenotypic alteration12
The dynamics of Mycobacterium tuberculosis phagosome and the fate of infection12
CircTNPO1 promotes the tumorigenesis of osteosarcoma by sequestering miR-578 to upregulate WNT5A expression12
Construction of crizotinib resistant models with CD74-ROS1 D2033N and CD74-ROS1 S1986F point mutations to explore resistance mechanism and treatment strategy12
STING activation and overcoming the challenges associated with STING agonists using ADC (antibody-drug conjugate) and other delivery systems12
Blocking the MIR155HG/miR-155 axis reduces CTGF-induced inflammatory cytokine production and α-SMA expression via upregulating AZGP1 in hypertrophic scar fibroblasts12
LGR4 promotes tumorigenesis by activating TGF-β1/Smad signaling pathway in multiple myeloma12
Upregulated miR-374a-5p drives psoriasis pathogenesis through WIF1 downregulation and Wnt5a/NF-κB activation12
Aquaporin proteins: A promising frontier for therapeutic intervention in cerebral ischemic injury12
Protein kinase B (Akt) blockade inhibits LH/hCG-mediated 17,20-lyase, but not 17α-hydroxylase activity of Cyp17a1 in mouse Leydig cell steroidogenesis12
Chemotherapy-induced acute vascular injury involves intracellular generation of ROS via activation of the acid sphingomyelinase pathway12
The implication of ROCK 2 as a potential senotherapeutic target via the suppression of the harmful effects of the SASP: Do senescent cancer cells really engulf the other cells?12
The PRX-1/TLR4 axis promotes hypoxia-induced radiotherapy resistance in non-small cell lung cancer by targeting the NF-κB/p65 pathway12
Role of moesin in the effect of glucagon-like peptide-1 on advanced glycation end products-induced endothelial barrier dysfunction12
Adenine nucleotide translocase 2, a putative target protein for 2-carba cyclic phosphatidic acid in microglial cells12
Editorial Board12
MicroRNA-155 suppressed cholesterol-induced matrix degradation, pyroptosis and apoptosis by targeting RORα in nucleus pulposus cells12
Investigation of the function of the PI3-Kinase / AKT signaling pathway for leukemogenesis and therapy of acute childhood lymphoblastic leukemia (ALL)12
Loss of ADAR1 induces ferroptosis of breast cancer cells12
Inhibitory effects of Formononetin on CoCrMo particle-induced osteoclast activation and bone loss through downregulating NF-κB and MAPK signaling12
Exosomal lncRNA ROR1-AS1 from cancer-associated fibroblasts inhibits ferroptosis of lung cancer cells through the IGF2BP1/SLC7A11 signal axis12
Lin28a induced mitochondrial dysfunction in human granulosa cells via suppressing LARS2 expression12
CircHIPK3 regulates cementoblast differentiation via the miR-10b-5p/DOHH/NF-κB axis12
Editorial Board12
The emerging crosstalk between atherosclerosis-related microRNAs and Bermuda triangle of foam cells: Cholesterol influx, trafficking, and efflux12
Corrigendum to “MicroRNA-206 in human cancer: Mechanistic and clinical perspectives” [Cellular Signalling, volume 101, Article 110525]12
PTX promotes breast cancer migration and invasion by recruiting ATF4 to upregulate FGF1912
The protein kinases of Dictyostelia and their incorporation into a signalome12
EP300 promotes renal tubular epithelial cell fibrosis by increasing HIF2α expression in diabetic nephropathy11
NK cell-based immunotherapy in hepatocellular carcinoma: An attractive therapeutic option for the next decade11
Trafficking of adhesion and aggregation-modulating proteins during the early stages of Dictyostelium development11
Regulation of mRNA translation in stem cells; links to brain disorders11
New insights into the relationship of mitochondrial metabolism and atherosclerosis11
DNMT3A R882H mutation promotes acute leukemic cell survival by regulating glycolysis through the NRF2/NQO1 axis11
P4HA1 activates HMGCS1 to promote nasopharyngeal carcinoma ferroptosis resistance and progression11
SIRT5-mediated GLS and GDH desuccinylation attenuates the autophagy of bovine mammary epithelial cells induced by ammonia11
Immune checkpoints signature-based risk stratification for prognosis of patients with gastric cancer11
Inhibition of phosphodiesterase 5A by tadalafil improves SIRT1 expression and activity in insulin-resistant podocytes11
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