Molecular Carcinogenesis

Article	Citations
UBE2D1 promotes glioblastoma proliferation by modulating p21 ubiquitination	60
The FOXO1/G6PC axis promotes gastric cancer progression and mediates 5‐fluorouracil resistance by targeting the PI3K/AKT/mTOR signaling pathway	32
Inhibition of the RBMS1/PRNP axis improves ferroptosis resistance‐mediated oxaliplatin chemoresistance in colorectal cancer	32
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Issue Information ‐ Ed Board	31
The Parkinson's disease‐associated protein α‐synuclein inhibits hepatoma by exosome delivery	29
Forkhead Box Q1 is a novel regulator of autophagy in breast cancer cells	28
Predictive Value of Neutrophil Extracellular Traps in Neoadjuvant Chemotherapy for Muscle‐Invasive Bladder Cancer	28
Cover Image, Volume 62, Issue 4	28
Delta‐Like Homolog 2 Facilitates Malignancy of Hepatocellular Carcinoma via Activating EGFR/PKM2 Signaling Pathway	26
Comprehensive analysis of PTEN‐related ceRNA network revealing the key pathways WDFY3‐AS2 ‐ miR‐21‐5p/miR‐221‐3p/miR‐222‐3p ‐ TIMP3 as potential biomarker in tumorigenesis and prognosis of kidney rena	26
Potentiated effects of lactate receptor GPR81 on immune microenvironment in breast cancer	26
Risk SNP‐mediated LINC01614 upregulation drives head and neck squamous cell carcinoma progression via PI3K/AKT signaling pathway	25
HNRNPC promotes estrogen receptor‐positive breast cancer cell cycle by stabilizing WDR77 mRNA in an m6A‐dependent manner	24
IRF2BP2 drives lymphatic metastasis in OSCC cells by elevating mitochondrial fission‐dependent fatty acid oxidation	24
SIRT1 promotes doxorubicin‐induced breast cancer drug resistance and tumor angiogenesis via regulating GSH‐mediated redox homeostasis	22
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RELA promotes the progression of oral squamous cell carcinoma via TFAP2A‐Wnt/β‐catenin signaling	21
PTPN2 Expression in Hypopharyngeal Squamous Cell Carcinoma and Its Clinical Significance	21
Histone lactylation facilitates hepatocellular carcinoma progression by upregulating endothelial cell‐specific molecule 1 expression	21
Atypical BCR‐ABL1 transcript in mixed phenotype acute leukemia with bone marrow necrosis	20
Issue Information ‐ Ed Board	20
Hepatitis B Virus X Protein Contributes to Hepatocellular Carcinoma via Upregulation of KIAA1429 Methyltransferase and mRNA m6A Hypermethylation of HSPG2/Perlecan	20
Issue Information ‐ Ed Board	20
Conditional deletion of mTOR discloses its essential role in early B‐cell development	19

Blocking the ATR‐SerRS‐VEGFA pathway targets angiogenesis for UV‐induced cutaneous squamous cell carcinoma	19
Homologous recombination repair gene mutations in colorectal cancer favors treatment of immune checkpoint inhibitors	18
Correction to “Cucurbitacin B Induces Inhibitory Effects via CIP2A/PP2A/Akt Pathway in Glioblastoma Multiforme”	18
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Loss of CBX2 causes genomic instability and Wnt activation in high grade serous ovarian carcinoma cells	17
VPS45 Contributes to the Progression of Hepatocellular Carcinoma by Triggering the Wnt/β‐Catenin Signaling Pathway	17
Issue Information ‐ Ed Board	16
Identification of concurrent STAT3::RARA and RARA::STAT5b fusions in a variant APL case	15
Transmembrane protein 147, as a potential Sorafenib target, could expedite cell cycle process and confer adverse prognosis in hepatocellular carcinoma	15
Oncogenic fusion of CD63‐BCAR4 contributes cancer stem cell‐like properties via ALDH1 activity	15
A potential signaling axis between RON kinase receptor and hypoxia‐inducible factor‐1 alpha in pancreatic cancer	14
Circ_0007429/miR‐637/TRIM71/Ago2 axis participates in the regulation of proliferation, migration, invasion, apoptosis, and aerobic glycolysis of HCC	14
DNTT activation, TdT‐aided gene length mutation, and better prognosis in ATG‐based regimen allo‐HSCT in AML	14
Transglutaminase 2 enhances hepatocyte growth factor signaling to drive the mesothelioma cancer cell phenotype	14
ELOVL6 promotes the progression of head and neck squamous cell carcinoma via activating WNT/β‐catenin pathway	13
The pancreatic cancer immune tumor microenvironment is negatively remodeled by gemcitabine while TGF‐β receptor plus dual checkpoint inhibition maintains antitumor immune cells	13
Transcriptional activation of S100A2 expression by HIF‐1α via binding to the hypomethylated hypoxia response elements in HCC cells	13
Role of solute carrier transporters SLC25A17 and SLC27A6 in acquired resistance to enzalutamide in castration‐resistant prostate cancer	13
Intratumoural heterogeneity and clone evolution of oral squamous cell carcinoma	13
AKR1C3 suppresses ferroptosis in hepatocellular carcinoma through regulation of YAP/SLC7A11 signaling pathway	13
YTHDF1 enhances stemness and chemoresistance in triple‐negative breast cancer cells by upregulating SIAH2	13
Plakophilin 1 in carcinogenesis	12
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Potential Crosstalk Between ANXA1+ Epithelial Cells and FABP4+ TAM Cells of Ferroptosis‐Related Molecular Clusters Promotes an Immunosuppressive Microenvironment in Non‐Small Cell Lung Cancer	12
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LATS‐regulated nuclear‐cytoplasmic translocation of SREBP2 inhibits hepatocellular carcinoma cell migration and invasion via epithelial–mesenchymal transition	12
Immunomodulatory role of thrombin in cancer progression	12
β‐Elemene Inhibits Adrenocortical Carcinoma Cell Proliferation and Migration, and Induces Apoptosis by Up‐Regulating miR‐486‐3p/Targeting NPTX1 Axis	11
Divergence of mutational signatures in association with breast cancer subtype	11
Retraction	11
Associations of genetically predicted circulating insulin‐like growth factor‐1 and insulin‐like growth factor binding protein‐3 with bladder cancer risk	11
KNTC1 knockdown inhibits the proliferation and migration of osteosarcoma cells by MCM2	11
Issue Information ‐ Ed Board	11
Role of hemoglobin alpha and hemoglobin beta in non‐small‐cell lung cancer based on bioinformatics analysis	11
Tissue‐of‐origin for cancers determines HIF‐1 activation induced phenotypic heterogeneity	11
Levels of Bile Acid Metabolism Are Associated With Alterations of Gut Microbes in Hepatocellular Carcinoma	11
SNORD60 promotes the tumorigenesis and progression of endometrial cancer through binding PIK3CA and regulating PI3K/AKT/mTOR signaling pathway	10
PARP5B is required for nonhomologous end joining during tumorigenesis in vivo	10
Triterpenoid ursolic acid drives metabolic rewiring and epigenetic reprogramming in treatment/prevention of human prostate cancer	10
HDAC inhibitor regulates the tumor immune microenvironment via pyroptosis in triple negative breast cancer	10
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HMGB3 Contributes to Anti‐PD‐1 Resistance by Inhibiting IFN‐γ‐Driven Ferroptosis in TNBC	10
Upregulation of collagen type X alpha 1 promotes the progress of triple‐negative breast cancer via Wnt/β‐catenin signaling	10
A‐to‐I‐Edited miR‐1304‐3p Inhibits Glycolysis and Tumor Growth of Esophageal Squamous Cell Carcinoma by Inactivating Wnt5a/ROR2 Signaling	10
M2 macrophage exosome‐derived Apoc1 promotes ferroptosis resistance in osteosarcoma by inhibiting ACSF2 deubiquitination	10
Splicing factor SRSF3 promotes the progression of cervical cancer through regulating DDX5	10
Issue Information ‐ Ed Board	10
Imatinib Impedes EMT and Notch Signalling by Inhibiting p300 Acetyltransferase in Breast Cancer Cells	10
Doublecortin‐like kinase 1 is a therapeutic target in squamous cell carcinoma	10

CYP4F11, an NRF2 Target Gene, Promotes Hepatocellular Carcinoma Cell Growth	10
Stage‐specific differential expression of zinc transporter SLC30A and SLC39A family proteins during prostate tumorigenesis	10
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Predictive significance of PRR11 in prognosis and immune infiltration of glioma patients	10
Epidermal growth factor receptor signaling in precancerous keratinocytes promotes neighboring head and neck cancer squamous cell carcinoma cancer stem cell‐like properties and phosphoinositide 3‐kinas	9
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Loss of PTPRS elicits potent metastatic capability and resistance to temozolomide in glioblastoma	9
Computed Tomography‐Based Radiomics and Genomics Analyses for Survival Prediction of Stage III Unresectable Non‐Small Cell Lung Cancer Treated With Definitive Chemoradiotherapy and Immunotherapy	9
A variant in CYP26B1 associated with esophageal squamous cell carcinoma risk by affecting retinoic acid metabolism	9
A systems biology‐based approach to screen key splicing factors in hepatocellular carcinoma	9
The JAK3Q988P mutation reveals oncogenic potential and resistance to ruxolitinib	9
Review: PD‐L1 as an emerging target in the treatment and prevention of keratinocytic skin cancer	9
Integrative Bioinformatics Analysis and Experimental Study of NLRP12 Reveal Its Prognostic Value and Potential Functions in Ovarian Cancer	9
Genetic variations associated with telomere length predict the risk of recurrence of non‐oropharyngeal head and neck squamous cell carcinoma	9
Diosmetin: A dietary flavone as modulator of signaling pathways in cancer progression	9
Breast cancer malignancy is governed by regulation of the macroH2A2/TM4SF1 axis, the AKT/NF‐κB pathway, and elevated MMP13 expression	9
The cumulative antitumor effects of regorafenib and radiotherapy in hepatocellular carcinoma	8
Association of SIRT6 Expression With Risk of Pneumonitis Induced by Radiotherapy in Cancer Patients	8
HER3 V104 mutations regulate cell signaling, growth, and drug sensitivity in cancer	8
Issue Information ‐ Ed Board	8
MicroRNA‐505‐5p/‐3p Regulates the Proliferation, Invasion, Apoptosis, and Temozolomide Resistance in Mesenchymal Glioma Stem Cells by Targeting AUF1	8
circEIF3I Promotes Colorectal Cancer Metastasis by Regulating the miR‐328‐3p/NCAPH Axis	8
EXPRESSION OF CONCERN: Growth Inhibition of Pancreatic Cancer Cells by Histone Deacetylase Inhibitor Belinostat Through Suppression of Multiple Pathways Including Hif, Nfkb, and Mtor Signaling	8
Regulation of programmed death ligand 1 (PD‐L1) expression by TNF‐related apoptosis‐inducing ligand (TRAIL) in triple‐negative breast cancer cells	8
Cover Image, Volume 62, Issue 2	8
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GRP78 promotes bone metastasis of prostate cancer by regulating bone microenvironment through Sonic hedgehog signaling	8
TRIM16 E121D variant affects the risk and prognosis of hepatocellular carcinoma by modulating the Wnt/β‐catenin pathway	8
Energy balance‐related factors in childhood and adolescence and risk of colorectal cancer based on KRAS, PIK3CA, and BRAF mutations and MMR status	8
Low expression of lncRNA SBF2‐AS1 regulates the miR‐302b‐3p/TGFBR2 axis, promoting metastasis in laryngeal cancer	8
The HDAC2–MTA3 interaction induces nonsmall cell lung cancer cell migration and invasion by targeting c‐Myc and cyclin D1	8
Mitogen‐activated protein kinase‐activated protein kinase‐2 (MK2) and its role in cell survival, inflammatory signaling, and migration in promoting cancer	8
Targeting Hippo/YAP in intrahepatic cholangiocarcinoma: Promising molecules in cancer therapy	8
Corrigendum	8
Issue Information ‐ Ed Board	8
Sulforaphane impaired immune checkpoint blockade therapy through activating ΔNP63α/PD‐L1 axis in gastric cancer	7
SIRT1 inhibition‐induced senescence as a strategy to prevent prostate cancer progression	7
Benzo[a]pyrene diol epoxide‐induced transformed cells identify the significance of hsa_circ_0051488, a ERCC1‐derived circular RNA in pulmonary squamous cell carcinoma	7
Deciphering CD4+ T cell‐mediated responses against cancer	7
TP53 mutations in head and neck cancer	7
Triiodothyronine (T3) suppresses hepatic tumorigenesis and development by inhibiting the phosphorylation of ERK	7
CircSPAG16 suppresses cadmium‐induced transformation of human bronchial epithelial cells by decoying PIP5K1α to inactivate Akt	7
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BORIS variant SF2(C2/A4) promotes the malignant development of liver cancer by activating epithelial‐mesenchymal transition and hepatic stellate cells	7
Transcription factor Nrf2 binds to circRNAPIBF1 to regulate SOD2 in lung adenocarcinoma progression	7
Transcriptome profiling reveals that VNPP433‐3β, the lead next‐generation galeterone analog inhibits prostate cancer stem cells by downregulating epithelial–mesenchymal transition and stem cell marker	7
Corrigendum	7
circPPP2R4 promotes colorectal cancer progression and reduces ROS production through the miR‐646/FOXK1 axis	7
HIF‐1α regulates the cell viability in radioiodine‐resistant papillary thyroid carcinoma cells induced by hypoxia through PKM2/NF‐κB signaling pathway	7
Baicalein promotes KDM4E to induce BICD1 and inhibit triple‐negative breast cancer progression by blocking PAR1 signaling	7
KCNE3 Facilitates M1 Macrophage Polarization by Suppressing the Wnt/β‐Catenin Pathway, Inhibiting Glioma Proliferation, Migration, and Invasion	7
Four and a half LIM domains 2 (FHL2) attenuates tumorigenesis of gastrointestinal stromal tumors (GISTs) by negatively regulating KIT signaling	6
Pharmacologic approaches to amino acid depletion for cancer therapy	6
Corrigendum	6
ZNF480 Accelerates Chemotherapy Resistance in Breast Cancer by Competing With TRIM28 and Stabilizing LSD1 to Upregulate the AKT‐GSK3β‐Snail Pathway	6
Alkaliptosis induction counteracts paclitaxel‐resistant ovarian cancer cells via ATP6V0D1‐mediated ABCB1 inhibition	6
Regulation of SELENOF translation by eIF4a3: Possible role in prostate cancer progression	6
TMED3 stabilizes SMAD2 by counteracting NEDD4‐mediated ubiquitination to promote ovarian cancer	6
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NSUN2 promotes lung adenocarcinoma progression through stabilizing PIK3R2 mRNA in an m5C‐dependent manner	6
CDK10 suppresses metastasis of lung adenocarcinoma through inhibition of the ETS2/c‐Raf/p‐MEK/p‐ERK signaling loop	6
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microRNA‐2117 Negatively Regulates Liver Cancer Stem Cells Expansion and Chemoresistance Via Targeting SOX2	6
ACKR3 orchestrates Hedgehog signaling to promote renal cell carcinoma progression	6
Dihydroartemisinin synergistically enhances the cytotoxic effects of oxaliplatin in colon cancer by targeting the PHB2‐RCHY1 mediated signaling pathway	6
CD137 Protein Expression Pattern Determines the Functional Role of Galectin‐9 in Colorectal Cancer	6
Tex10 interacts with STAT3 to regulate hepatocellular carcinoma growth and metastasis	6
SRPK1 Activation Facilitates Gli3S664 Phosphorylation and Promotes Metastasis in Esophageal Squamous Cell Carcinoma	6
HHLA2 promotes hepatoma cell proliferation, migration, and invasion via SPP1/PI3K/AKT signaling pathway	6
Associations of mitochondrial DNA copy number with incident risks of gastrointestinal cancers: A prospective case–cohort study	6
Metabolism‐focused CRISPR screen unveils mitochondrial pyruvate carrier 1 as a critical driver for PARP inhibitor resistance in lung cancer	6
Setting up clinical trials for success: Applying preclinical advances in combined TGFβ/PD‐L1 inhibition to ongoing clinical studies	6
Lesser prevalence of polyps/WNT‐dysregulation and concomitant upregulation of gamma‐catenin/MYC point to alternate pathways in colorectal cancer in India	6
Cover Image, Volume 63, Issue 5	6
Withaferin A mediated changes of miRNA expression in breast cancer‐derived mammospheres	6
Systematic evaluation of the predictive gene expression signatures of immune checkpoint inhibitors in metastatic melanoma	6
γ‐Tocotrienol enhances autophagy of gastric cancer cells by the regulation of GSK3β/β‐Catenin pathway	6
Characterizing Genetic Susceptibility to Colorectal Cancer in Taiwan Through Genome‐Wide Association Study	6
ATP citrate lyase promotes the progression of hepatocellular carcinoma by activating the REGγ‐proteasome pathway	6

KIF4A promotes genomic stability and progression of endometrial cancer through regulation of TPX2 protein degradation	6
Dysregulated BCL9 Controls Tumorigenicity and Ferroptosis Susceptibility by Binding With Nrf2 in Thyroid Carcinoma	6
FOXD3 suppresses epithelial–mesenchymal transition through direct transcriptional promotion of SMAD7 in esophageal squamous cell carcinoma	5
Adipocytes Promote Endometrial Cancer Progression Through Activation of the SIRT1‐HMMR Signaling Axis	5
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KLHDC7B as a novel diagnostic biomarker in urine exosomal mRNA promotes bladder urothelial carcinoma cell proliferation and migration, inhibits apoptosis	5
BATF promotes extramedullary infiltration through TGF‐β1/Smad/MMPs axis in acute myeloid leukemia	5
FAP positive cancer‐associated fibroblasts promote tumor progression and radioresistance in esophageal squamous cell carcinoma by transferring exosomal lncRNA AFAP1‐AS1	5
Loss of SETD2‐mediated downregulation of intracellular and exosomal miRNA‐10b determines MAPK pathway activation and multidrug resistance in renal cancer	5
Expression of Concern: Amplification of Cyclinl1 in Uterine Cervical Carcinoma Has Prognostic Implications	5
CircDUSP1 regulates tumor growth, metastasis, and paclitaxel sensitivity in triple‐negative breast cancer by targeting miR‐761/DACT2 signaling axis	5
CNOT4 suppresses nonsmall cell lung cancer progression by promoting the degradation of PAF1	5
Hypoxia Promotes Malignant Progression of Colorectal Cancer by Inducing POSTN+ Cancer‐Associated Fibroblast Formation	5
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A systems biology approach and in vitro experiment indicated Rapamycin targets key cancer and cell cycle‐related genes and miRNAs in triple‐negative breast cancer cells	5
Corrigendum	5
The efficacy and safety of pH‐responsive and photothermal‐sensitive multifunctional nanoparticles loaded with cryptotanshinone for the treatment of gastric cancer	5
Precision therapy for cancer prevention by targeting carcinogenesis	5
Drug‐target Mendelian randomization revealed a significant association of genetically proxied metformin effects with increased prostate cancer risk	5
Role of vitamin D3 in tumor aggressiveness and radiation response for hepatocellular carcinoma	5
Issue Information ‐ Ed Board	5
Molecular Analysis of Genes CEBPA, NPM1, IDH1, and RUNX1 Polymorphisms as Biomarker Potential in Leukemia Patients	5
Tumor‐derived extracellular vesicles confer 5‐fluorouracil resistance in esophageal cancer via long noncoding RNA AC116025.2 delivery	5
Issue Information ‐ Ed Board	5
G2 and S phase‐expressed‐1 induces chromosomal instability in esophageal squamous cell carcinoma cells and inhibits cell apoptosis through ROS/JNK signaling	5
Issue Information ‐ Ed Board	5
FAPhigh α‐SMAlow cancer‐associated fibroblast‐derived SLPI protein encapsulated in extracellular vesicles promotes ovarian cancer development via activation of PI3K/AKT and downs	5
NUAK family kinase 2 is a novel therapeutic target for prostate cancer	5
KIN17 promotes cell migration and invasion through stimulating the TGF‐β/Smad2 pathway in hepatocellular carcinoma	5
Mass cytometry and transcriptomic profiling reveal PD1 blockade induced alterations in oral carcinogenesis	5
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The serine protease CORIN promotes progression of gastric cancer by mediating the ERK1/2 MAPK pathway	5
PKMYT1 induced by YAP/TEAD1 gives rise to the progression and worse prognosis of bladder cancer	5
Daurisoline suppresses esophageal squamous cell carcinoma growth in vitro and in vivo by targeting MEK1/2 kinase	5
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Issue Information ‐ Ed Board	5