Molecular Carcinogenesis

Papers
(The TQCC of Molecular Carcinogenesis is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)
ArticleCitations
UBE2D1 promotes glioblastoma proliferation by modulating p21 ubiquitination64
Issue Information ‐ Ed Board37
Cover Image, Volume 62, Issue 435
Forkhead Box Q1 is a novel regulator of autophagy in breast cancer cells35
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Combined Inhibition of XPO1 and DNA Methylation Exerts Synergistic Effects in DLBCL31
HNRNPC promotes estrogen receptor‐positive breast cancer cell cycle by stabilizing WDR77 mRNA in an m6A‐dependent manner31
The Parkinson's disease‐associated protein α‐synuclein inhibits hepatoma by exosome delivery29
Delta‐Like Homolog 2 Facilitates Malignancy of Hepatocellular Carcinoma via Activating EGFR/PKM2 Signaling Pathway28
PTPN2 Expression in Hypopharyngeal Squamous Cell Carcinoma and Its Clinical Significance28
Comprehensive analysis of PTEN‐related ceRNA network revealing the key pathways WDFY3‐AS2 ‐ miR‐21‐5p/miR‐221‐3p/miR‐222‐3p ‐ TIMP3 as potential biomarker in tumorigenesis and prognosis of kidney rena27
Risk SNP‐mediated LINC01614 upregulation drives head and neck squamous cell carcinoma progression via PI3K/AKT signaling pathway27
Inhibition of the RBMS1/PRNP axis improves ferroptosis resistance‐mediated oxaliplatin chemoresistance in colorectal cancer26
The FOXO1/G6PC axis promotes gastric cancer progression and mediates 5‐fluorouracil resistance by targeting the PI3K/AKT/mTOR signaling pathway25
Potentiated effects of lactate receptor GPR81 on immune microenvironment in breast cancer25
IRF2BP2 drives lymphatic metastasis in OSCC cells by elevating mitochondrial fission‐dependent fatty acid oxidation23
RELA promotes the progression of oral squamous cell carcinoma via TFAP2A‐Wnt/β‐catenin signaling23
Histone lactylation facilitates hepatocellular carcinoma progression by upregulating endothelial cell‐specific molecule 1 expression22
Predictive Value of Neutrophil Extracellular Traps in Neoadjuvant Chemotherapy for Muscle‐Invasive Bladder Cancer22
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SIRT1 promotes doxorubicin‐induced breast cancer drug resistance and tumor angiogenesis via regulating GSH‐mediated redox homeostasis22
Hepatitis B Virus X Protein Contributes to Hepatocellular Carcinoma via Upregulation of KIAA1429 Methyltransferase and mRNA m6A Hypermethylation of HSPG2/Perlecan22
Issue Information ‐ Ed Board19
Issue Information ‐ Ed Board19
Atypical BCR‐ABL1 transcript in mixed phenotype acute leukemia with bone marrow necrosis19
Conditional deletion of mTOR discloses its essential role in early B‐cell development18
Blocking the ATR‐SerRS‐VEGFA pathway targets angiogenesis for UV‐induced cutaneous squamous cell carcinoma18
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Correction to “Cucurbitacin B Induces Inhibitory Effects via CIP2A/PP2A/Akt Pathway in Glioblastoma Multiforme”16
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Loss of CBX2 causes genomic instability and Wnt activation in high grade serous ovarian carcinoma cells16
Transglutaminase 2 enhances hepatocyte growth factor signaling to drive the mesothelioma cancer cell phenotype15
Oncogenic fusion of CD63‐BCAR4 contributes cancer stem cell‐like properties via ALDH1 activity15
Circ_0007429/miR‐637/TRIM71/Ago2 axis participates in the regulation of proliferation, migration, invasion, apoptosis, and aerobic glycolysis of HCC15
Issue Information ‐ Ed Board15
Transmembrane protein 147, as a potential Sorafenib target, could expedite cell cycle process and confer adverse prognosis in hepatocellular carcinoma15
AKR1C3 suppresses ferroptosis in hepatocellular carcinoma through regulation of YAP/SLC7A11 signaling pathway15
Transcriptional activation of S100A2 expression by HIF‐1α via binding to the hypomethylated hypoxia response elements in HCC cells14
VPS45 Contributes to the Progression of Hepatocellular Carcinoma by Triggering the Wnt/β‐Catenin Signaling Pathway14
YTHDF1 enhances stemness and chemoresistance in triple‐negative breast cancer cells by upregulating SIAH214
Role of solute carrier transporters SLC25A17 and SLC27A6 in acquired resistance to enzalutamide in castration‐resistant prostate cancer14
ELOVL6 promotes the progression of head and neck squamous cell carcinoma via activating WNT/β‐catenin pathway14
Venetoclax Synergizes With Regorafenib for Colorectal Cancer by Targeting BCL‐214
DNTT activation, TdT‐aided gene length mutation, and better prognosis in ATG‐based regimen allo‐HSCT in AML14
Homologous recombination repair gene mutations in colorectal cancer favors treatment of immune checkpoint inhibitors14
HORMAD1 Polymorphisms Influence Susceptibility to Esophageal Squamous Cell Carcinoma Through Gene–Smoking Interaction13
The pancreatic cancer immune tumor microenvironment is negatively remodeled by gemcitabine while TGF‐β receptor plus dual checkpoint inhibition maintains antitumor immune cells13
Identification of concurrent STAT3::RARA and RARA::STAT5b fusions in a variant APL case13
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β‐Elemene Inhibits Adrenocortical Carcinoma Cell Proliferation and Migration, and Induces Apoptosis by Up‐Regulating miR‐486‐3p/Targeting NPTX1 Axis12
Divergence of mutational signatures in association with breast cancer subtype12
Potential Crosstalk Between ANXA1+ Epithelial Cells and FABP4+ TAM Cells of Ferroptosis‐Related Molecular Clusters Promotes an Immunosuppressive Microenvironment in Non‐Small Cell Lung Cancer12
SNORD60 promotes the tumorigenesis and progression of endometrial cancer through binding PIK3CA and regulating PI3K/AKT/mTOR signaling pathway12
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Tissue‐of‐origin for cancers determines HIF‐1 activation induced phenotypic heterogeneity12
Issue Information ‐ Ed Board12
Doublecortin‐like kinase 1 is a therapeutic target in squamous cell carcinoma11
Stage‐specific differential expression of zinc transporter SLC30A and SLC39A family proteins during prostate tumorigenesis11
A‐to‐I‐Edited miR‐1304‐3p Inhibits Glycolysis and Tumor Growth of Esophageal Squamous Cell Carcinoma by Inactivating Wnt5a/ROR2 Signaling11
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KNTC1 knockdown inhibits the proliferation and migration of osteosarcoma cells by MCM211
PARP5B is required for nonhomologous end joining during tumorigenesis in vivo11
Imatinib Impedes EMT and Notch Signalling by Inhibiting p300 Acetyltransferase in Breast Cancer Cells11
Role of hemoglobin alpha and hemoglobin beta in non‐small‐cell lung cancer based on bioinformatics analysis11
Upregulation of collagen type X alpha 1 promotes the progress of triple‐negative breast cancer via Wnt/β‐catenin signaling11
LATS‐regulated nuclear‐cytoplasmic translocation of SREBP2 inhibits hepatocellular carcinoma cell migration and invasion via epithelial–mesenchymal transition11
CYP4F11, an NRF2 Target Gene, Promotes Hepatocellular Carcinoma Cell Growth11
Splicing factor SRSF3 promotes the progression of cervical cancer through regulating DDX511
Immunomodulatory role of thrombin in cancer progression10
Levels of Bile Acid Metabolism Are Associated With Alterations of Gut Microbes in Hepatocellular Carcinoma10
Issue Information ‐ Ed Board10
Predictive significance of PRR11 in prognosis and immune infiltration of glioma patients10
Triterpenoid ursolic acid drives metabolic rewiring and epigenetic reprogramming in treatment/prevention of human prostate cancer10
Inhibition of Growth and Survival of Head and Neck Cancer Cells by Silibinin Involves the Down‐Regulation of Erk1/2, AKT and STAT3 Signaling10
HDAC inhibitor regulates the tumor immune microenvironment via pyroptosis in triple negative breast cancer10
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Computed Tomography‐Based Radiomics and Genomics Analyses for Survival Prediction of Stage III Unresectable Non‐Small Cell Lung Cancer Treated With Definitive Chemoradiotherapy and Immunotherapy10
HMGB3 Contributes to Anti‐PD‐1 Resistance by Inhibiting IFN‐γ‐Driven Ferroptosis in TNBC10
M2 macrophage exosome‐derived Apoc1 promotes ferroptosis resistance in osteosarcoma by inhibiting ACSF2 deubiquitination10
Plakophilin 1 in carcinogenesis10
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Review: PD‐L1 as an emerging target in the treatment and prevention of keratinocytic skin cancer10
Regulation of programmed death ligand 1 (PD‐L1) expression by TNF‐related apoptosis‐inducing ligand (TRAIL) in triple‐negative breast cancer cells9
The cumulative antitumor effects of regorafenib and radiotherapy in hepatocellular carcinoma9
Integrative Bioinformatics Analysis and Experimental Study of NLRP12 Reveal Its Prognostic Value and Potential Functions in Ovarian Cancer9
The JAK3Q988P mutation reveals oncogenic potential and resistance to ruxolitinib9
Loss of PTPRS elicits potent metastatic capability and resistance to temozolomide in glioblastoma9
Cover Image, Volume 62, Issue 29
Breast cancer malignancy is governed by regulation of the macroH2A2/TM4SF1 axis, the AKT/NF‐κB pathway, and elevated MMP13 expression9
Mitogen‐activated protein kinase‐activated protein kinase‐2 (MK2) and its role in cell survival, inflammatory signaling, and migration in promoting cancer9
Diosmetin: A dietary flavone as modulator of signaling pathways in cancer progression9
Genetic variations associated with telomere length predict the risk of recurrence of non‐oropharyngeal head and neck squamous cell carcinoma9
HER3 V104 mutations regulate cell signaling, growth, and drug sensitivity in cancer9
Association of SIRT6 Expression With Risk of Pneumonitis Induced by Radiotherapy in Cancer Patients9
A systems biology‐based approach to screen key splicing factors in hepatocellular carcinoma9
Energy balance‐related factors in childhood and adolescence and risk of colorectal cancer based on KRAS, PIK3CA, and BRAF mutations and MMR status9
Epidermal growth factor receptor signaling in precancerous keratinocytes promotes neighboring head and neck cancer squamous cell carcinoma cancer stem cell‐like properties and phosphoinositide 3‐kinas9
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EXPRESSION OF CONCERN: Growth Inhibition of Pancreatic Cancer Cells by Histone Deacetylase Inhibitor Belinostat Through Suppression of Multiple Pathways Including Hif, Nfkb, and Mtor Signaling 9
Low expression of lncRNA SBF2‐AS1 regulates the miR‐302b‐3p/TGFBR2 axis, promoting metastasis in laryngeal cancer9
Sulforaphane impaired immune checkpoint blockade therapy through activating ΔNP63α/PD‐L1 axis in gastric cancer8
TP53 mutations in head and neck cancer8
KCNE3 Facilitates M1 Macrophage Polarization by Suppressing the Wnt/β‐Catenin Pathway, Inhibiting Glioma Proliferation, Migration, and Invasion8
BORIS variant SF2(C2/A4) promotes the malignant development of liver cancer by activating epithelial‐mesenchymal transition and hepatic stellate cells8
Targeting Hippo/YAP in intrahepatic cholangiocarcinoma: Promising molecules in cancer therapy8
Issue Information ‐ Ed Board8
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circEIF3I Promotes Colorectal Cancer Metastasis by Regulating the miR‐328‐3p/NCAPH Axis8
Triiodothyronine (T3) suppresses hepatic tumorigenesis and development by inhibiting the phosphorylation of ERK8
Corrigendum8
Baicalein promotes KDM4E to induce BICD1 and inhibit triple‐negative breast cancer progression by blocking PAR1 signaling8
TRIM16 E121D variant affects the risk and prognosis of hepatocellular carcinoma by modulating the Wnt/β‐catenin pathway8
A variant in CYP26B1 associated with esophageal squamous cell carcinoma risk by affecting retinoic acid metabolism8
Transcriptome profiling reveals that VNPP433‐3β, the lead next‐generation galeterone analog inhibits prostate cancer stem cells by downregulating epithelial–mesenchymal transition and stem cell marker8
HIF‐1α regulates the cell viability in radioiodine‐resistant papillary thyroid carcinoma cells induced by hypoxia through PKM2/NF‐κB signaling pathway8
Deciphering CD4+ T cell‐mediated responses against cancer8
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Transcription factor Nrf2 binds to circRNAPIBF1 to regulate SOD2 in lung adenocarcinoma progression8
GRP78 promotes bone metastasis of prostate cancer by regulating bone microenvironment through Sonic hedgehog signaling8
MicroRNA‐505‐5p/‐3p Regulates the Proliferation, Invasion, Apoptosis, and Temozolomide Resistance in Mesenchymal Glioma Stem Cells by Targeting AUF18
Corrigendum8
Issue Information ‐ Ed Board8
The HDAC2–MTA3 interaction induces nonsmall cell lung cancer cell migration and invasion by targeting c‐Myc and cyclin D18
Monocarboxylate Transporter‐1 Is Dispensable for Hepatocellular Carcinoma Development8
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Pharmacologic approaches to amino acid depletion for cancer therapy7
CDK10 suppresses metastasis of lung adenocarcinoma through inhibition of the ETS2/c‐Raf/p‐MEK/p‐ERK signaling loop7
GRPEL2 Modulates Apoptosis in Esophageal Squamous Cell Carcinoma via the JNK Signaling Pathway7
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Systematic evaluation of the predictive gene expression signatures of immune checkpoint inhibitors in metastatic melanoma7
circPPP2R4 promotes colorectal cancer progression and reduces ROS production through the miR‐646/FOXK1 axis7
Four and a half LIM domains 2 (FHL2) attenuates tumorigenesis of gastrointestinal stromal tumors (GISTs) by negatively regulating KIT signaling7
HHLA2 promotes hepatoma cell proliferation, migration, and invasion via SPP1/PI3K/AKT signaling pathway7
SRPK1 Activation Facilitates Gli3S664 Phosphorylation and Promotes Metastasis in Esophageal Squamous Cell Carcinoma7
SIRT1 inhibition‐induced senescence as a strategy to prevent prostate cancer progression7
ATP citrate lyase promotes the progression of hepatocellular carcinoma by activating the REGγ‐proteasome pathway7
Corrigendum7
Dysregulated BCL9 Controls Tumorigenicity and Ferroptosis Susceptibility by Binding With Nrf2 in Thyroid Carcinoma7
Metabolism‐focused CRISPR screen unveils mitochondrial pyruvate carrier 1 as a critical driver for PARP inhibitor resistance in lung cancer7
Associations of mitochondrial DNA copy number with incident risks of gastrointestinal cancers: A prospective case–cohort study7
KIF4A promotes genomic stability and progression of endometrial cancer through regulation of TPX2 protein degradation7
NSUN2 promotes lung adenocarcinoma progression through stabilizing PIK3R2 mRNA in an m5C‐dependent manner7
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Lesser prevalence of polyps/WNT‐dysregulation and concomitant upregulation of gamma‐catenin/MYC point to alternate pathways in colorectal cancer in India7
TMED3 stabilizes SMAD2 by counteracting NEDD4‐mediated ubiquitination to promote ovarian cancer6
Regulation of SELENOF translation by eIF4a3: Possible role in prostate cancer progression6
Alkaliptosis induction counteracts paclitaxel‐resistant ovarian cancer cells via ATP6V0D1‐mediated ABCB1 inhibition6
Dihydroartemisinin synergistically enhances the cytotoxic effects of oxaliplatin in colon cancer by targeting the PHB2‐RCHY1 mediated signaling pathway6
Tumor‐derived extracellular vesicles confer 5‐fluorouracil resistance in esophageal cancer via long noncoding RNA AC116025.2 delivery6
Loss of SETD2‐mediated downregulation of intracellular and exosomal miRNA‐10b determines MAPK pathway activation and multidrug resistance in renal cancer6
Mass cytometry and transcriptomic profiling reveal PD1 blockade induced alterations in oral carcinogenesis6
FOXD3 suppresses epithelial–mesenchymal transition through direct transcriptional promotion of SMAD7 in esophageal squamous cell carcinoma6
Issue Information ‐ Ed Board6
CD137 Protein Expression Pattern Determines the Functional Role of Galectin‐9 in Colorectal Cancer6
γ‐Tocotrienol enhances autophagy of gastric cancer cells by the regulation of GSK3β/β‐Catenin pathway6
microRNA‐2117 Negatively Regulates Liver Cancer Stem Cells Expansion and Chemoresistance Via Targeting SOX26
ACKR3 orchestrates Hedgehog signaling to promote renal cell carcinoma progression6
ZNF480 Accelerates Chemotherapy Resistance in Breast Cancer by Competing With TRIM28 and Stabilizing LSD1 to Upregulate the AKT‐GSK3β‐Snail Pathway6
Issue Information ‐ Ed Board6
NUAK family kinase 2 is a novel therapeutic target for prostate cancer6
Drug‐target Mendelian randomization revealed a significant association of genetically proxied metformin effects with increased prostate cancer risk6
CNOT4 suppresses nonsmall cell lung cancer progression by promoting the degradation of PAF16
Expression of Concern: Amplification of Cyclinl1 in Uterine Cervical Carcinoma Has Prognostic Implications6
Withaferin A mediated changes of miRNA expression in breast cancer‐derived mammospheres6
Tex10 interacts with STAT3 to regulate hepatocellular carcinoma growth and metastasis6
Setting up clinical trials for success: Applying preclinical advances in combined TGFβ/PD‐L1 inhibition to ongoing clinical studies6
Characterizing Genetic Susceptibility to Colorectal Cancer in Taiwan Through Genome‐Wide Association Study6
Cover Image, Volume 63, Issue 56
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TRAF6 Exerts Tumor‐Promoting Effects via Genetic and Autophagic Modulation in Gastric Cancer6
PKMYT1 induced by YAP/TEAD1 gives rise to the progression and worse prognosis of bladder cancer6
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Downregulation of cellular retinoic acid binding protein 1 fosters epithelial–mesenchymal transition in thyroid cancer5
Solamargine inhibits the growth of hepatocellular carcinoma and enhances the anticancer effect of sorafenib by regulating HOTTIP‐TUG1/miR‐4726‐5p/MUC1 pathway5
JD‐02, a novel Hsp90 inhibitor, induces ROS/SRC axis‐dependent cytoprotective autophagy in colorectal cancer cells5
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Spatial Transcriptomic Landscape of Canine Oral Squamous Cell Carcinoma5
Hypoxia Promotes Malignant Progression of Colorectal Cancer by Inducing POSTN+ Cancer‐Associated Fibroblast Formation5
Molecular Analysis of Genes CEBPA, NPM1, IDH1, and RUNX1 Polymorphisms as Biomarker Potential in Leukemia Patients5
Adipocytes Promote Endometrial Cancer Progression Through Activation of the SIRT1‐HMMR Signaling Axis5
Issue Information ‐ Ed Board5
CircDUSP1 regulates tumor growth, metastasis, and paclitaxel sensitivity in triple‐negative breast cancer by targeting miR‐761/DACT2 signaling axis5
Role of vitamin D3 in tumor aggressiveness and radiation response for hepatocellular carcinoma5
Uncovering the Role of DNA Repair Impairment in UVA‐Induced Mutagenesis in Human Xeroderma Pigmentosum Variant Cells5
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KIF4A Inhibits Ferroptosis in Glioblastoma via the CHMP4B/GPX4 Axis and Promotes Temozolomide Resistance5
PDZ‐binding kinase aggravates pancreatic neuroendocrine neoplasm progression by activating the AKT/mTOR pathway5
KIN17 promotes cell migration and invasion through stimulating the TGF‐β/Smad2 pathway in hepatocellular carcinoma5
Effect of CHRDL1 on angiogenesis and metastasis of colorectal cancer cells via TGF‐β/VEGF pathway5
Pregnane X Receptor Activation Induces Ferroptosis Resistance Through Upregulation of FSP15
The efficacy and safety of pH‐responsive and photothermal‐sensitive multifunctional nanoparticles loaded with cryptotanshinone for the treatment of gastric cancer5
The serine protease CORIN promotes progression of gastric cancer by mediating the ERK1/2 MAPK pathway5
A systems biology approach and in vitro experiment indicated Rapamycin targets key cancer and cell cycle‐related genes and miRNAs in triple‐negative breast cancer cells5
FAPhigh α‐SMAlow cancer‐associated fibroblast‐derived SLPI protein encapsulated in extracellular vesicles promotes ovarian cancer development via activation of PI3K/AKT and downs5
Precision therapy for cancer prevention by targeting carcinogenesis5
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Evaluation and Comparison of Prognostic Multigene Tests in Early‐Stage Breast Cancer: Which Is the Most Effective? A Literature Review Exploring Clinical Utility to Enhance Therapeutic Management in L5
Corrigendum5
Autophagy awakens—the myriad roles of autophagy in head and neck cancer development and therapeutic response5
Inhibition of endogenous hydrogen sulfide production suppresses the growth of nasopharyngeal carcinoma cells5
G2 and S phase‐expressed‐1 induces chromosomal instability in esophageal squamous cell carcinoma cells and inhibits cell apoptosis through ROS/JNK signaling5
Integrated Genomics Reveal Potential Resistance Mechanisms of PANoptosis‐Associated Genes in Acute Myeloid Leukemia5
FAP positive cancer‐associated fibroblasts promote tumor progression and radioresistance in esophageal squamous cell carcinoma by transferring exosomal lncRNA AFAP1‐AS15
Identification of Plasma rRNA‐Derived Small RNA Biomarkers for Diagnosis of Colorectal Cancer5
KLHDC7B as a novel diagnostic biomarker in urine exosomal mRNA promotes bladder urothelial carcinoma cell proliferation and migration, inhibits apoptosis5
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BATF promotes extramedullary infiltration through TGF‐β1/Smad/MMPs axis in acute myeloid leukemia5
Glutamine, Serine and Glycine at Increasing Concentrations Regulate Cisplatin Sensitivity in Gastric Cancer by Posttranslational Modifications of KDM4A5
Daurisoline suppresses esophageal squamous cell carcinoma growth in vitro and in vivo by targeting MEK1/2 kinase5
Issue Information ‐ Ed Board5
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