Molecular Carcinogenesis

Article	Citations
UBE2D1 promotes glioblastoma proliferation by modulating p21 ubiquitination	60
The FOXO1/G6PC axis promotes gastric cancer progression and mediates 5‐fluorouracil resistance by targeting the PI3K/AKT/mTOR signaling pathway	34
Issue Information ‐ Ed Board	33
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The Parkinson's disease‐associated protein α‐synuclein inhibits hepatoma by exosome delivery	31
Predictive Value of Neutrophil Extracellular Traps in Neoadjuvant Chemotherapy for Muscle‐Invasive Bladder Cancer	30
Cover Image, Volume 62, Issue 4	29
Forkhead Box Q1 is a novel regulator of autophagy in breast cancer cells	29
PTPN2 Expression in Hypopharyngeal Squamous Cell Carcinoma and Its Clinical Significance	27
Inhibition of the RBMS1/PRNP axis improves ferroptosis resistance‐mediated oxaliplatin chemoresistance in colorectal cancer	26
Potentiated effects of lactate receptor GPR81 on immune microenvironment in breast cancer	26
SIRT1 promotes doxorubicin‐induced breast cancer drug resistance and tumor angiogenesis via regulating GSH‐mediated redox homeostasis	26
Delta‐Like Homolog 2 Facilitates Malignancy of Hepatocellular Carcinoma via Activating EGFR/PKM2 Signaling Pathway	25
Comprehensive analysis of PTEN‐related ceRNA network revealing the key pathways WDFY3‐AS2 ‐ miR‐21‐5p/miR‐221‐3p/miR‐222‐3p ‐ TIMP3 as potential biomarker in tumorigenesis and prognosis of kidney rena	24
IRF2BP2 drives lymphatic metastasis in OSCC cells by elevating mitochondrial fission‐dependent fatty acid oxidation	23
Risk SNP‐mediated LINC01614 upregulation drives head and neck squamous cell carcinoma progression via PI3K/AKT signaling pathway	23
Histone lactylation facilitates hepatocellular carcinoma progression by upregulating endothelial cell‐specific molecule 1 expression	22
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HNRNPC promotes estrogen receptor‐positive breast cancer cell cycle by stabilizing WDR77 mRNA in an m6A‐dependent manner	21
RELA promotes the progression of oral squamous cell carcinoma via TFAP2A‐Wnt/β‐catenin signaling	21
Hepatitis B Virus X Protein Contributes to Hepatocellular Carcinoma via Upregulation of KIAA1429 Methyltransferase and mRNA m6A Hypermethylation of HSPG2/Perlecan	21
Atypical BCR‐ABL1 transcript in mixed phenotype acute leukemia with bone marrow necrosis	20
Issue Information ‐ Ed Board	20
Issue Information ‐ Ed Board	20
Conditional deletion of mTOR discloses its essential role in early B‐cell development	19

Blocking the ATR‐SerRS‐VEGFA pathway targets angiogenesis for UV‐induced cutaneous squamous cell carcinoma	19
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Homologous recombination repair gene mutations in colorectal cancer favors treatment of immune checkpoint inhibitors	18
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Issue Information ‐ Ed Board	16
Loss of CBX2 causes genomic instability and Wnt activation in high grade serous ovarian carcinoma cells	16
Oncogenic fusion of CD63‐BCAR4 contributes cancer stem cell‐like properties via ALDH1 activity	15
Circ_0007429/miR‐637/TRIM71/Ago2 axis participates in the regulation of proliferation, migration, invasion, apoptosis, and aerobic glycolysis of HCC	15
Transmembrane protein 147, as a potential Sorafenib target, could expedite cell cycle process and confer adverse prognosis in hepatocellular carcinoma	15
Intratumoural heterogeneity and clone evolution of oral squamous cell carcinoma	14
A potential signaling axis between RON kinase receptor and hypoxia‐inducible factor‐1 alpha in pancreatic cancer	14
Transglutaminase 2 enhances hepatocyte growth factor signaling to drive the mesothelioma cancer cell phenotype	14
DNTT activation, TdT‐aided gene length mutation, and better prognosis in ATG‐based regimen allo‐HSCT in AML	14
Transcriptional activation of S100A2 expression by HIF‐1α via binding to the hypomethylated hypoxia response elements in HCC cells	14
Role of solute carrier transporters SLC25A17 and SLC27A6 in acquired resistance to enzalutamide in castration‐resistant prostate cancer	14
AKR1C3 suppresses ferroptosis in hepatocellular carcinoma through regulation of YAP/SLC7A11 signaling pathway	13
Identification of concurrent STAT3::RARA and RARA::STAT5b fusions in a variant APL case	13
YTHDF1 enhances stemness and chemoresistance in triple‐negative breast cancer cells by upregulating SIAH2	13
Correction to “Cucurbitacin B Induces Inhibitory Effects via CIP2A/PP2A/Akt Pathway in Glioblastoma Multiforme”	13
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ELOVL6 promotes the progression of head and neck squamous cell carcinoma via activating WNT/β‐catenin pathway	13
The pancreatic cancer immune tumor microenvironment is negatively remodeled by gemcitabine while TGF‐β receptor plus dual checkpoint inhibition maintains antitumor immune cells	13
VPS45 Contributes to the Progression of Hepatocellular Carcinoma by Triggering the Wnt/β‐Catenin Signaling Pathway	13
Potential Crosstalk Between ANXA1+ Epithelial Cells and FABP4+ TAM Cells of Ferroptosis‐Related Molecular Clusters Promotes an Immunosuppressive Microenvironment in Non‐Small Cell Lung Cancer	12
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Associations of genetically predicted circulating insulin‐like growth factor‐1 and insulin‐like growth factor binding protein‐3 with bladder cancer risk	12
SNORD60 promotes the tumorigenesis and progression of endometrial cancer through binding PIK3CA and regulating PI3K/AKT/mTOR signaling pathway	12
β‐Elemene Inhibits Adrenocortical Carcinoma Cell Proliferation and Migration, and Induces Apoptosis by Up‐Regulating miR‐486‐3p/Targeting NPTX1 Axis	11
Issue Information ‐ Ed Board	11
Retraction	11
Tissue‐of‐origin for cancers determines HIF‐1 activation induced phenotypic heterogeneity	11
LATS‐regulated nuclear‐cytoplasmic translocation of SREBP2 inhibits hepatocellular carcinoma cell migration and invasion via epithelial–mesenchymal transition	11
Imatinib Impedes EMT and Notch Signalling by Inhibiting p300 Acetyltransferase in Breast Cancer Cells	11
Role of hemoglobin alpha and hemoglobin beta in non‐small‐cell lung cancer based on bioinformatics analysis	11
Divergence of mutational signatures in association with breast cancer subtype	11
Levels of Bile Acid Metabolism Are Associated With Alterations of Gut Microbes in Hepatocellular Carcinoma	11
KNTC1 knockdown inhibits the proliferation and migration of osteosarcoma cells by MCM2	11
Triterpenoid ursolic acid drives metabolic rewiring and epigenetic reprogramming in treatment/prevention of human prostate cancer	10
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Doublecortin‐like kinase 1 is a therapeutic target in squamous cell carcinoma	10
M2 macrophage exosome‐derived Apoc1 promotes ferroptosis resistance in osteosarcoma by inhibiting ACSF2 deubiquitination	10
HDAC inhibitor regulates the tumor immune microenvironment via pyroptosis in triple negative breast cancer	10
HMGB3 Contributes to Anti‐PD‐1 Resistance by Inhibiting IFN‐γ‐Driven Ferroptosis in TNBC	10
Splicing factor SRSF3 promotes the progression of cervical cancer through regulating DDX5	10
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PARP5B is required for nonhomologous end joining during tumorigenesis in vivo	10
Immunomodulatory role of thrombin in cancer progression	10
Stage‐specific differential expression of zinc transporter SLC30A and SLC39A family proteins during prostate tumorigenesis	10
Plakophilin 1 in carcinogenesis	10
Upregulation of collagen type X alpha 1 promotes the progress of triple‐negative breast cancer via Wnt/β‐catenin signaling	10

A‐to‐I‐Edited miR‐1304‐3p Inhibits Glycolysis and Tumor Growth of Esophageal Squamous Cell Carcinoma by Inactivating Wnt5a/ROR2 Signaling	10
CYP4F11, an NRF2 Target Gene, Promotes Hepatocellular Carcinoma Cell Growth	10
Predictive significance of PRR11 in prognosis and immune infiltration of glioma patients	9
Breast cancer malignancy is governed by regulation of the macroH2A2/TM4SF1 axis, the AKT/NF‐κB pathway, and elevated MMP13 expression	9
The JAK3Q988P mutation reveals oncogenic potential and resistance to ruxolitinib	9
Epidermal growth factor receptor signaling in precancerous keratinocytes promotes neighboring head and neck cancer squamous cell carcinoma cancer stem cell‐like properties and phosphoinositide 3‐kinas	9
Computed Tomography‐Based Radiomics and Genomics Analyses for Survival Prediction of Stage III Unresectable Non‐Small Cell Lung Cancer Treated With Definitive Chemoradiotherapy and Immunotherapy	9
Integrative Bioinformatics Analysis and Experimental Study of NLRP12 Reveal Its Prognostic Value and Potential Functions in Ovarian Cancer	9
Genetic variations associated with telomere length predict the risk of recurrence of non‐oropharyngeal head and neck squamous cell carcinoma	9
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Issue Information ‐ Ed Board	9
Review: PD‐L1 as an emerging target in the treatment and prevention of keratinocytic skin cancer	9
A variant in CYP26B1 associated with esophageal squamous cell carcinoma risk by affecting retinoic acid metabolism	9
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The cumulative antitumor effects of regorafenib and radiotherapy in hepatocellular carcinoma	8
Issue Information ‐ Ed Board	8
MicroRNA‐505‐5p/‐3p Regulates the Proliferation, Invasion, Apoptosis, and Temozolomide Resistance in Mesenchymal Glioma Stem Cells by Targeting AUF1	8
Regulation of programmed death ligand 1 (PD‐L1) expression by TNF‐related apoptosis‐inducing ligand (TRAIL) in triple‐negative breast cancer cells	8
Loss of PTPRS elicits potent metastatic capability and resistance to temozolomide in glioblastoma	8
Energy balance‐related factors in childhood and adolescence and risk of colorectal cancer based on KRAS, PIK3CA, and BRAF mutations and MMR status	8
Mitogen‐activated protein kinase‐activated protein kinase‐2 (MK2) and its role in cell survival, inflammatory signaling, and migration in promoting cancer	8
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Diosmetin: A dietary flavone as modulator of signaling pathways in cancer progression	8
Low expression of lncRNA SBF2‐AS1 regulates the miR‐302b‐3p/TGFBR2 axis, promoting metastasis in laryngeal cancer	8
A systems biology‐based approach to screen key splicing factors in hepatocellular carcinoma	8
EXPRESSION OF CONCERN: Growth Inhibition of Pancreatic Cancer Cells by Histone Deacetylase Inhibitor Belinostat Through Suppression of Multiple Pathways Including Hif, Nfkb, and Mtor Signaling	8
Association of SIRT6 Expression With Risk of Pneumonitis Induced by Radiotherapy in Cancer Patients	8
Issue Information ‐ Ed Board	8
Targeting Hippo/YAP in intrahepatic cholangiocarcinoma: Promising molecules in cancer therapy	8
Cover Image, Volume 62, Issue 2	8
HER3 V104 mutations regulate cell signaling, growth, and drug sensitivity in cancer	8
The HDAC2–MTA3 interaction induces nonsmall cell lung cancer cell migration and invasion by targeting c‐Myc and cyclin D1	8
Baicalein promotes KDM4E to induce BICD1 and inhibit triple‐negative breast cancer progression by blocking PAR1 signaling	7
TRIM16 E121D variant affects the risk and prognosis of hepatocellular carcinoma by modulating the Wnt/β‐catenin pathway	7
BORIS variant SF2(C2/A4) promotes the malignant development of liver cancer by activating epithelial‐mesenchymal transition and hepatic stellate cells	7
TP53 mutations in head and neck cancer	7
Corrigendum	7
SIRT1 inhibition‐induced senescence as a strategy to prevent prostate cancer progression	7
KCNE3 Facilitates M1 Macrophage Polarization by Suppressing the Wnt/β‐Catenin Pathway, Inhibiting Glioma Proliferation, Migration, and Invasion	7
HIF‐1α regulates the cell viability in radioiodine‐resistant papillary thyroid carcinoma cells induced by hypoxia through PKM2/NF‐κB signaling pathway	7
Deciphering CD4+ T cell‐mediated responses against cancer	7
Corrigendum	7
Benzo[a]pyrene diol epoxide‐induced transformed cells identify the significance of hsa_circ_0051488, a ERCC1‐derived circular RNA in pulmonary squamous cell carcinoma	7
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Sulforaphane impaired immune checkpoint blockade therapy through activating ΔNP63α/PD‐L1 axis in gastric cancer	7
Dysregulated BCL9 Controls Tumorigenicity and Ferroptosis Susceptibility by Binding With Nrf2 in Thyroid Carcinoma	7
Transcriptome profiling reveals that VNPP433‐3β, the lead next‐generation galeterone analog inhibits prostate cancer stem cells by downregulating epithelial–mesenchymal transition and stem cell marker	7
circEIF3I Promotes Colorectal Cancer Metastasis by Regulating the miR‐328‐3p/NCAPH Axis	7
Transcription factor Nrf2 binds to circRNAPIBF1 to regulate SOD2 in lung adenocarcinoma progression	7
GRP78 promotes bone metastasis of prostate cancer by regulating bone microenvironment through Sonic hedgehog signaling	7
Triiodothyronine (T3) suppresses hepatic tumorigenesis and development by inhibiting the phosphorylation of ERK	7
circPPP2R4 promotes colorectal cancer progression and reduces ROS production through the miR‐646/FOXK1 axis	7
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Setting up clinical trials for success: Applying preclinical advances in combined TGFβ/PD‐L1 inhibition to ongoing clinical studies	6
γ‐Tocotrienol enhances autophagy of gastric cancer cells by the regulation of GSK3β/β‐Catenin pathway	6
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SRPK1 Activation Facilitates Gli3S664 Phosphorylation and Promotes Metastasis in Esophageal Squamous Cell Carcinoma	6
CDK10 suppresses metastasis of lung adenocarcinoma through inhibition of the ETS2/c‐Raf/p‐MEK/p‐ERK signaling loop	6
TMED3 stabilizes SMAD2 by counteracting NEDD4‐mediated ubiquitination to promote ovarian cancer	6
ACKR3 orchestrates Hedgehog signaling to promote renal cell carcinoma progression	6
CNOT4 suppresses nonsmall cell lung cancer progression by promoting the degradation of PAF1	6
Issue Information ‐ Ed Board	6
Cover Image, Volume 63, Issue 5	6
Regulation of SELENOF translation by eIF4a3: Possible role in prostate cancer progression	6
microRNA‐2117 Negatively Regulates Liver Cancer Stem Cells Expansion and Chemoresistance Via Targeting SOX2	6
Alkaliptosis induction counteracts paclitaxel‐resistant ovarian cancer cells via ATP6V0D1‐mediated ABCB1 inhibition	6
ATP citrate lyase promotes the progression of hepatocellular carcinoma by activating the REGγ‐proteasome pathway	6
Lesser prevalence of polyps/WNT‐dysregulation and concomitant upregulation of gamma‐catenin/MYC point to alternate pathways in colorectal cancer in India	6
KIF4A promotes genomic stability and progression of endometrial cancer through regulation of TPX2 protein degradation	6
Associations of mitochondrial DNA copy number with incident risks of gastrointestinal cancers: A prospective case–cohort study	6
NSUN2 promotes lung adenocarcinoma progression through stabilizing PIK3R2 mRNA in an m5C‐dependent manner	6
Systematic evaluation of the predictive gene expression signatures of immune checkpoint inhibitors in metastatic melanoma	6
Tumor‐derived extracellular vesicles confer 5‐fluorouracil resistance in esophageal cancer via long noncoding RNA AC116025.2 delivery	6
Issue Information ‐ Ed Board	6
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HHLA2 promotes hepatoma cell proliferation, migration, and invasion via SPP1/PI3K/AKT signaling pathway	6
Withaferin A mediated changes of miRNA expression in breast cancer‐derived mammospheres	6
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Dihydroartemisinin synergistically enhances the cytotoxic effects of oxaliplatin in colon cancer by targeting the PHB2‐RCHY1 mediated signaling pathway	6
Four and a half LIM domains 2 (FHL2) attenuates tumorigenesis of gastrointestinal stromal tumors (GISTs) by negatively regulating KIT signaling	6

GRPEL2 Modulates Apoptosis in Esophageal Squamous Cell Carcinoma via the JNK Signaling Pathway	6
Pharmacologic approaches to amino acid depletion for cancer therapy	6
Metabolism‐focused CRISPR screen unveils mitochondrial pyruvate carrier 1 as a critical driver for PARP inhibitor resistance in lung cancer	6
CD137 Protein Expression Pattern Determines the Functional Role of Galectin‐9 in Colorectal Cancer	6
Characterizing Genetic Susceptibility to Colorectal Cancer in Taiwan Through Genome‐Wide Association Study	6
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Tex10 interacts with STAT3 to regulate hepatocellular carcinoma growth and metastasis	6
Corrigendum	6
ZNF480 Accelerates Chemotherapy Resistance in Breast Cancer by Competing With TRIM28 and Stabilizing LSD1 to Upregulate the AKT‐GSK3β‐Snail Pathway	6
Spatial Transcriptomic Landscape of Canine Oral Squamous Cell Carcinoma	5
A systems biology approach and in vitro experiment indicated Rapamycin targets key cancer and cell cycle‐related genes and miRNAs in triple‐negative breast cancer cells	5
Mass cytometry and transcriptomic profiling reveal PD1 blockade induced alterations in oral carcinogenesis	5
Expression of Concern: Amplification of Cyclinl1 in Uterine Cervical Carcinoma Has Prognostic Implications	5
Drug‐target Mendelian randomization revealed a significant association of genetically proxied metformin effects with increased prostate cancer risk	5
CircDUSP1 regulates tumor growth, metastasis, and paclitaxel sensitivity in triple‐negative breast cancer by targeting miR‐761/DACT2 signaling axis	5
Issue Information ‐ Ed Board	5
Effect of CHRDL1 on angiogenesis and metastasis of colorectal cancer cells via TGF‐β/VEGF pathway	5
Integrated Genomics Reveal Potential Resistance Mechanisms of PANoptosis‐Associated Genes in Acute Myeloid Leukemia	5
Hypoxia Promotes Malignant Progression of Colorectal Cancer by Inducing POSTN+ Cancer‐Associated Fibroblast Formation	5
Precision therapy for cancer prevention by targeting carcinogenesis	5
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Molecular Analysis of Genes CEBPA, NPM1, IDH1, and RUNX1 Polymorphisms as Biomarker Potential in Leukemia Patients	5
The efficacy and safety of pH‐responsive and photothermal‐sensitive multifunctional nanoparticles loaded with cryptotanshinone for the treatment of gastric cancer	5
NUAK family kinase 2 is a novel therapeutic target for prostate cancer	5
FOXD3 suppresses epithelial–mesenchymal transition through direct transcriptional promotion of SMAD7 in esophageal squamous cell carcinoma	5
BATF promotes extramedullary infiltration through TGF‐β1/Smad/MMPs axis in acute myeloid leukemia	5
FAP positive cancer‐associated fibroblasts promote tumor progression and radioresistance in esophageal squamous cell carcinoma by transferring exosomal lncRNA AFAP1‐AS1	5
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Solamargine inhibits the growth of hepatocellular carcinoma and enhances the anticancer effect of sorafenib by regulating HOTTIP‐TUG1/miR‐4726‐5p/MUC1 pathway	5
Role of vitamin D3 in tumor aggressiveness and radiation response for hepatocellular carcinoma	5
KIN17 promotes cell migration and invasion through stimulating the TGF‐β/Smad2 pathway in hepatocellular carcinoma	5
KLHDC7B as a novel diagnostic biomarker in urine exosomal mRNA promotes bladder urothelial carcinoma cell proliferation and migration, inhibits apoptosis	5
Adipocytes Promote Endometrial Cancer Progression Through Activation of the SIRT1‐HMMR Signaling Axis	5
Issue Information ‐ Ed Board	5
Loss of SETD2‐mediated downregulation of intracellular and exosomal miRNA‐10b determines MAPK pathway activation and multidrug resistance in renal cancer	5
PKMYT1 induced by YAP/TEAD1 gives rise to the progression and worse prognosis of bladder cancer	5
The serine protease CORIN promotes progression of gastric cancer by mediating the ERK1/2 MAPK pathway	5
Glutamine, Serine and Glycine at Increasing Concentrations Regulate Cisplatin Sensitivity in Gastric Cancer by Posttranslational Modifications of KDM4A	5
G2 and S phase‐expressed‐1 induces chromosomal instability in esophageal squamous cell carcinoma cells and inhibits cell apoptosis through ROS/JNK signaling	5
Corrigendum	5
Daurisoline suppresses esophageal squamous cell carcinoma growth in vitro and in vivo by targeting MEK1/2 kinase	5
FAPhigh α‐SMAlow cancer‐associated fibroblast‐derived SLPI protein encapsulated in extracellular vesicles promotes ovarian cancer development via activation of PI3K/AKT and downs	5