Experimental Dermatology

Article	Citations
	88
INZ‐701, a recombinant ENPP1 enzyme, prevents ectopic calcification in an Abcc6−/− mouse model of pseudoxanthoma elasticum	59
Author Index	56
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Confocal microscopy and optical coherence tomography of inflammatory skin diseases in hairs and pilosebaceous units: A systematic review	48
Gastrointestinal and hepatic manifestations in patients with generalised pustular psoriasis	47
Issue Information	39
Granzyme B inhibition reduces autoantibody‐induced dermal–epidermal separation in an ex vivo model of epidermolysis bullosa acquisita	39
Circ_0001402 knockdown suppresses the chemoresistance and development of DDP‐resistant cutaneous squamous cell carcinoma cells by functioning as a ceRNA for miR‐625‐5p	38
Ultraviolet B irradiation increases the expression of cornulin and retepin in human skin xenotransplants	37
Lithium chloride promotes mesenchymal‐epithelial transition in murine cutaneous wound healing via inhibiting CXCL9 and IGF2	35
Follicular melanoma—A rare entity: First description of an association with a nevus	35
Unique Integrated Confocal Raman Microspectroscopy and LC‐OCT in a Single Device for Advanced Diagnostic Approaches in Dermatology: An Individual Cases	32
Ceramides and Skin Health: New Insights	32
Unveiling the Link: The Potential Roles of Vitamin D in Keloid Pathophysiology	30
Role of nitric oxide in regulating epidermal permeability barrier function	30
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In vitro effects of wound‐dressings on key wound healing properties of dermal fibroblasts	29
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Does immune dysregulation contribute towards development of hypopigmentation in Indian post kala‐azar dermal leishmaniasis?	27
A Phase 1 randomized, open‐label clinical trial to evaluate the effect of a far‐infrared emitting patch on local skin perfusion, microcirculation and oxygenation	27
Meeting Report: 47th Annual Meeting of the “Arbeitsgemeinschaft Dermatologische Forschung”	27
RNA‐sequencing reveals plantar keloid has potential bone/cartilage characteristics	27
Clues for developing next‐generation cancer immunotherapy	27
Issue Information	26

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Cold atmospheric plasma reduces demodex count on the face comparably to topical ivermectin, as measured by reflectance confocal microscopy	25
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Melanin accumulation in dermal stem cells deteriorates their exosome‐mediated skin basement membrane construction in solar lentigo	23
Insights into adult atopic dermatitis heterogeneity derived from circulating biomarker profiling in patients with moderate‐to‐severe disease	23
Kynurenine inhibits melanogenesis in human melanocyte‐keratinocyte co‐cultures and in a reconstructed 3D skin model	23
CC chemokine ligand 20 (CCL20) positively regulates collagen type I production in 3D skin equivalent tissues	23
Laser‐assisted epicutaneous immunization to target human skin dendritic cells	22
The impacts of biologic treatment on metabolic profiling in psoriasis	22
Brain MRI findings in patients with bullous pemphigoid: A case–control study	22
Single‐cell RNA sequencing of a poorly metastatic melanoma cell line and its subclones with high lung and brain metastasis potential reveals gene expression signature of metastasis with pro	22
SLST D1 strains may contribute to skin health	21
Combatting ageing in dermal papilla cells and promoting hair follicle regeneration using exosomes from human hair follicle dermal sheath cup cells	21
Reversibly immortalization establishes a hair follicle stem cell line with hair follicle reconstruction ability	21
Issue Information	20
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Road‐traffic‐related air pollution contributes to skin barrier alteration and growth defect of sensory neurons	19
Understanding generalized pustular psoriasis for improved patient care	19
Serum leucine‐rich α2‐glycoprotein is a useful biomarker for generalized pustular psoriasis	19
High‐frequency ultrasound: A novel noninvasive tool for evaluation of specific layers of blistering	18
Infantile generalized pustular psoriasis with excellent response to secukinumab: A case report	18
ABCC6 deficiency and bone loss: A double benefit of etidronate for patient presenting with pseudoxanthoma elasticum?	18
Loss of ARHGAP40 expression in basal cell carcinoma via CpG island hypermethylation	18
Epigenetic regulation and signalling pathways in Merkel cell development	18
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Saprophytic bacteria and fungi colonize stearoyl coenzyme‐A desaturase‐1 knockout skin	17
Featured Cover	17
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The role of reflectance confocal microscopy in the diagnosis of eccrine poroma: A retrospective case–control study	17
Transcriptional analysis reveals distinct gene expression profiles of three bowenoid papulosis patients	17
Extremely hair follicle density is associated with a significantly different cecal microbiota in rex rabbits	17
Keratinocyte EGF signalling dominates in atopic dermatitis lesions: A comparative RNAseq analysis	17
Targeted deep sequencing reveals genomic alterations of actinic keratosis/cutaneous squamous cell carcinoma in situ and cutaneous squamous cell carcinoma	17
Skin ageing: Clinical aspects and in vivo microscopic patterns observed with reflectance confocal microscopy and optical coherence tomography	16
Loss of ATP2C1 function promotes trafficking and degradation of NOTCH1: Implications for Hailey‐Hailey disease	16
Skin microbiome signatures associated with psoriasis and seborrheic dermatitis	16
Sonophoresis enhances the skin penetration of 5‐aminolevulinic acid: A promising pretreatment for photodynamic therapy	16
Generation of induced pluripotent stem cell (iPSC) from NY‐ESO‐I‐specific cytotoxic T cells isolated from the melanoma patient with minor HLAs: The practical pilot stu	16
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Current views on neuropeptides in atopic dermatitis	16
Generalized pustular psoriasis: Quality and readability of online health information	15
Beneficial effects of coagulase‐negative Staphylococci on Staphylococcus aureus skin colonization	15
Induction and generalization of nocebo effects on itch	15
Design and validation of neuronal exocytosis blocking peptides as potential novel antiperspirants	15
The effect of PPAR isoform (de)activation on the lipid composition in full‐thickness skin models	15
Senescent cell removal via JAG1‐NOTCH1 signalling in the epidermis	15
Deep learning‐based semantic segmentation of non‐melanocytic skin tumors in whole‐slide histopathological images	14

Abstract	14
Pyoderma gangrenosum and impact on quality of life: A narrative review	14
The role of PI3'‐lipid signalling in melanoma initiation, progression and maintenance	14
Vesicular hand eczema transcriptome analysis provides insights into its pathophysiology	14
Tiered approach for evaluation of anti‐melanogenic activity of trans ‐ N ‐coumaroyltyramine derivatives	14
Identification of gut microbiota dysbiosis in bullous pemphigoid under different disease activity	13
Integrin α5 regulates motility of human monocyte‐derived Langerhans cells during immune response	13
A multimodal, comprehensive characterization of a cutaneous wound model in healthy volunteers	13
Effects of pulsed dye laser treatment in psoriasis: A nerve‐wrecking process?	13
Early redox homeostasis disruption contributes to the differential cytotoxicity of imiquimod on transformed and normal endothelial cells	13
Molecular Characteristics of Sweet Syndrome: A Systematic Review	13
Non‐invasive evaluation of subjective sensitive skin by transcriptomics using mRNA in skin surface lipids	13
Enhanced quality of hESC‐derived melanocytes through modified concentration of endothelin‐1	13
Utilizing systems genetics to enhance understanding into molecular targets of skin cancer	13
Issue Information	13
Objective hand eczema severity assessment with automated lesion anatomical stratification	13
STAT3‐induced lncRNA GNAS‐AS1 accelerates keloid formation by mediating the miR‐196a‐5p/CXCL12/STAT3 axis in a feedback loop	12
A deep learning algorithm to detect cutaneous squamous cell carcinoma on frozen sections in Mohs micrographic surgery: A retrospective assessment	12
A collagen biostimulator improves photoaging pigmentation	12
Genome‐wide association studies in Japanese women identified genetic loci associated with wrinkles and sagging	12
Nuclear receptors for epidermal lipid barrier: Advances in mechanisms and applications	12
How well can we predict Mohs micrographic surgery number of stages and reconstruction type? Reply to Shoham et al.	12
Increased Abnormal Erythrocytes Caused by Spleen Filtration Deficiency Provide a Hypoxic Environment for the Occurrence of Psoriasis	11
Pulmonary interstitial lesions in pemphigus mouse model: Verifying pemphigus may not be only limited to skin and mucosa	11
A new experimental model to measure the tension generated by cutaneous flaps	11
Cytokine induced 3‐D organotypic psoriasis skin model demonstrates distinct roles for NF‐κB and JAK pathways in disease pathophysiology	11
Hidradenitis suppurativa: A folliculotropic disease of innate immune barrier dysfunction?	11
Mental Health, Sleep and General Health Among Individuals With Dermatologic Conditions: A US Population‐Based Study Using the National Health and Nutrition Examination Survey (NHANES)	11
Molecular analysis of inflammatory diseases	11
Interleukin‐36 cytokines are overexpressed in the skin and sera of patients with bullous pemphigoid	11
Topical use of tobramycin: A possible innovative treatment of severe skin chronic ulcers	11
Mast cells are upregulated in hidradenitis suppurativa tissue, associated with epithelialized tunnels and normalized by spleen tyrosine kinase antagonism	11
Exosomes derived from human dermal fibroblasts (HDFn‐Ex) alleviate DNCB‐induced atopic dermatitis (AD) via PPARα	11
Spinal histamine H4 receptor mediates chronic pruritus via p‐ERK in acetone–ether–water (AEW)‐induced dry skin mice	11
Hsa_circ_0012919 promotes pyroptosis in CD4+T cells of systemic lupus erythematous by miR‐125a‐3p/GSDMD axis	11
Imiquimod‐induced ex vivo model of psoriatic human skin via interleukin‐17A signalling of T cells and Langerhans cells	10
The involvement of keratinocytes in pruritus of chronic inflammatory dermatosis	10
Functional preservation benefits of minimal surgery for extramammary Paget's disease	10
Hybrid of Deep Feature Extraction and Machine Learning Ensembles for Imbalanced Skin Cancer Datasets	10
Vorinostat, a histone deacetylase inhibitor, as a potential novel treatment for psoriasis	10
Neurofibromatosis Type 1 Patients With Epilepsy: A Comprehensive Analysis of Demographics, Comorbidities and Healthcare Outcomes	10
Secretomes as an emerging class of bioactive ingredients for enhanced cosmeceutical applications	10
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Hidradenitis suppurativa in skin of colour	10
Patients suffering from dystrophic epidermolysis bullosa are prone to developing autoantibodies against skin proteins: A longitudinal confirmational study	10
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NEDD4L Inhibits the Proliferation and Migration of Keloid Fibroblasts by Regulating YY1 Ubiquitination‐Mediated Glycolytic Metabolic Reprogramming	10
TSP1 promotes fibroblast proliferation and extracellular matrix deposition via the IL6/JAK2/STAT3 signalling pathway in keloids	10
TYK2 inhibition with deucravacitinib ameliorates erosive oral lichen planus	10
Spatial transcriptomics in human skin research	10
Effects of Emissions From Oriented Strand Board on the Development of Atopic Dermatitis Using Two Different Experimental Mouse Models	10
Efficacy and safety of topical JAK inhibitors in the treatment of atopic dermatitis in paediatrics and adults: A systematic review	10
New human in vitro co‐culture model of keratinocytes and sensory neurons like cells releasing substance P with an evaluation of the expression ofZIKVentry receptors: A potent opportunity to	9
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The dynamics of circulating tumour DNA (ctDNA) during treatment reflects tumour response in advanced melanoma patients	9
Senolytic Targeting of Anti‐Apoptotic Bcl Family Increases Cell Death in UV‐Irradiated Senescent Melanocytes: Search for Senolytics	9
A cross‐sectional cohort study on the skin microbiota in patients with different acne durations	9
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Interferon‐γ downregulates tight junction function, which is rescued by interleukin‐17A	9
Do Melanocytes Have a Role in Controlling Epidermal Bacterial Colonisation and the Skin Microbiome?	9
Issue Information	9
Meta‐analysis reveals a lower ‘UV signature’ in vitiligo skin compared to non‐melanoma skin cancers	9
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Analyses of tertiary lymphoid structures observed in cases of Merkel cell carcinoma showing spontaneous regression	9
Eosinophils in hidradenitis suppurativa patients exhibit pro‐inflammatory traits, implicating a potential pathogenic role in the disease	9
The Impacts of Seasonal Factors on Psoriasis	9
Simple tape‐stripping method for highly reliable and quantitative analysis of skin microbiome	9
Basophil‐Derived IL‐4 Production and Its Potential Pro‐Tumoural Role in Th2‐Polarisation Within Sentinel Lymph Nodes of Primary Cutaneous Melanoma	9
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Role of Siglec‐E in MC903‐Induced Atopic Dermatitis	8
Proposal for the optimal staging of extramammary Paget's disease: A retrospective analysis of 57 cases with distant metastasis	8
Fluoxetine exerts anti‐inflammatory effects on human epidermal keratinocytes and suppresses their endothelin release	8
The neuropeptide Substance P facilitates the transition from an inflammatory to proliferation phase‐associated responses in dermal fibroblasts	8
The Inflammatory Landscape of a Whole‐Tissue Explant Model of Hidradenitis Suppurativa	8
Transduction‐induced overexpression of Merkel cell T antigens in human hair follicles induces formation of pathological cell clusters with Merkel cell carcinoma‐like phenotype	8
A Genome‐Wide Survey of DNA Methylation Status in Whole Blood of Patients With Hidradenitis Suppurativa Suggests Systemic Immune Dysregulation and Systemic Disease Burden	8
Neurotensin counteracts hair growth inhibition induced by chronic restraint stress	8
Mutational landscape in squamous cell carcinoma of the nail unit	8
Dose Modulation Strategies in Psoriatic Patients: Real‐Life Pilot Comparison Between Risankizumab and Guselkumab up to 12 Months After Dose Spacing	8
Age‐related decrease in responsiveness of CD271 ‐positive skin stem cells to growth factors	8

Na+/H+ exchanger NHE1 is active at cell–cell contacts and facilitates cell dissemination during collective migration of melanoma cells	8
Concentration‐dependent stimulation of melanin production as well as melanocyte and keratinocyte proliferation by melatonin in human eyelid epidermis	8
Investigation of the pathogenesis of ADAR1 gene in dyschromatosis symmetrica hereditaria	8
5‐ALA loaded self‐adhesive patch‐PDT is effective and safe in the treatment of actinic keratoses on hands and arms	7
A randomized clinical study on the effects of emollient use on the developing infant skin microbiome and metabolome	7
IL‐4 and IL‐13 are not involved in IL‐31‐induced itch‐associated scratching behaviour in mice	7
Exploring sex differences in generalized pustular psoriasis hospitalizations	7
Novel mechanisms of microbial crosstalk with skin innate immunity	7
Altered structure indicating reduced barrier function of lesional compared to non‐lesional psoriatic skin—A non‐invasive in vivo study of the human stratum corneum with confocal Raman micro‐spectrosco	7
Influences of vitiligo‐associated characteristics on the occurrence of diabetes mellitus: Interactive analysis of a cross‐sectional study	7
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Issue Information	7
Analysis of circRNA profiles and clinical value in Stevens‐Johnson syndrome and toxic epidermal necrolysis	7
Bactogram: Spatial Analysis of Bacterial Colonisation in Epidermal Wounds	7
Mdivi‐1 alleviates atopic dermatitis through the inhibition of NLRP3 inflammasome	7
New Characteristics of Eccrine Sweat Glands in Acquired Idiopathic Generalised Anhidrosis as Determined via Three‐Dimensional Fluorescence Imaging of Cleared Skin Tissue	7
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Nuclear translocation of PKM2 mediates keratinocyte metabolic reprogramming in psoriasis	7
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Novel aspects of Raman spectroscopy in skin research	7
Anti‐allergic effect of ascorbic acid derivative DDH‐1 in a mouse model of atopic dermatitis	7
Presence of immunoglobulin E‐expressing antibody‐secreting cells in the dermis close to bullous pemphigoid lesions	7
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Impact of deficiency anaemia comorbidity in generalized pustular psoriasis hospitalizations	7
Human pluripotent stem cells: An alternative for 3D in vitro modelling of skin disease	7
Nutraceutical strategies for alleviation of UVB phototoxicity	7
Requisite instruments for the establishment of three‐dimensional epidermal human skin equivalents—A methods review	7
Genetic lineage tracing in skin reveals predominant expression of HEY2 in dermal papilla during telogen and that HEY2+ cells contribute to the regeneration of dermal c	7
The SHH‐GLI1 pathway is required in skin expansion and angiogenesis	7
Interplay between diabetes mellitus and atopic dermatitis	7
Following historical “tracks” of hair follicle miniaturisation in patterned hair loss: Are elastin bodies the forgotten aetiology?	7
Development of IL‐17A inhibitor‐induced atopic dermatitis‐like rash in psoriasis patients: Insights into immune shift	7
Topical metformin 30% gel in the treatment of acne vulgaris in women, a split face, placebo‐controlled study	7
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Mobile health technologies in an interventional hybrid study on actinic keratosis: Results from an early phase randomized controlled trial investigating the safety and efficacy of a cytosolic phosphol	7
Reply to Vargas, Peirano et al.	7
Analysis of optical absorption of photoaged human skin using a high‐frequency illumination microscopy analysis system	7
Target molecules for future hidradenitis suppurativa treatment	7
Hyperuricemia Exacerbates Psoriatic Inflammation by Inducing M1 Macrophage Activation and Th1 Cell Differentiation	7
Acropulpitis in systemic lupus erythematosus is associated with high type 1 interferon signature	6
The aryl hydrocarbon receptor at the forefront of host‐microbe interactions in the skin: A perspective on current knowledge gaps and directions for future research and therapeutic applications	6
Issue Information	6
In vivo visualisation of tattoo particles using multiphoton tomography and fluorescence lifetime imaging	6
Can contagious itch be affected by positive and negative suggestions?	6
IL‐38 orchestrates proliferation and differentiation in human keratinocytes	6
Skin epigenetics	6
Is there a relation between long non‐coding RNA MALAT‐1 and miRNA‐9 in Egyptian patients with Vitiligo?	6
The novel prognostic marker SPOCK2 regulates tumour progression in melanoma	6
Analysis of biomechanical properties of mouse skin dermis through atomic force microscopy: Application to demonstrate a sexual dimorphism	6
Dermatomyositis autoantigen CHD4 forms immune stimulatory complexes with endogenous DNA	6
Discovery of natural bispecific antibodies: Is psoriasis induced by a toxigenic Corynebacterium simulans and maintained by CIDAMPs as autoantigens?	6
CLDN1 knock out keratinocytes as a model to investigate multiple skin disorders	6
Issue Information	6
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Increase of ISG15 in psoriasis lesions and its promotion of keratinocyte proliferation via the Hif‐1α signalling pathway	6
Dysbiosis of nail microbiome in patients with psoriasis	6
Generating Skin‐Derived Precursor‐Like Cells From Human‐Induced Pluripotent Stem Cell‐Derived Skin Organoids	6
Unravelling the metabolic landscape of cutaneous melanoma: Insights from single‐cell sequencing analysis and machine learning for prognostic assessment of lactate metabolism	6
Human epidermis organotypic cultures, a reproducible system recapitulating the epidermis in vitro	6
Insight into the role of IRF7 in skin and connective tissue diseases	6
Observations that suggest a contribution of altered dermal papilla mitochondrial function to androgenetic alopecia	6
Issue Information	6
Polylysine dendrigraft is able to differentially impact Cutibacterium acnes strains preventing acneic skin	6
Spatiotemporal expression of NRAS and occurrence of giant congenital melanocytic nevi	6
Aged and young mice differentially respond to tape‐stripping in epidermal gene expression	6
Increased neutrophil‐derived IL‐17A identified in generalized pustular psoriasis	6
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GBP1 promotes cutaneous squamous cell carcinoma proliferation and invasion through activation of STAT3 by SP1	6
Dysregulation of Regulatory T Cells and Autoimmune Sequelae in DRESS: Insights From Flow Cytometry and NanoString Analysis	6
Pilot phase results of a prospective, randomized controlled trial of narrowband ultraviolet B phototherapy in hospitalized COVID‐19 patients	5
Gene expression profiling suggests severe, extensive central centrifugal cicatricial alopecia may be both clinically and biologically distinct from limited disease subtypes	5
A narrative review of studies assessing the quality of life in patients with generalized pustular psoriasis	5
Programmed cell death‐1 blockade therapy in melanoma: Resistance mechanisms and combination strategies	5
Melanin accumulation in acanthotic seborrheic keratosis: Reduced proliferation and early differentiation of keratinocytes and increased number of melanocytes	5
“Normal” TEWL‐how can it be defined? A systematic review	5
Research progress on the mechanism and signalling pathway of ferroptosis and its potential role in dermatosis research	5
Retyping and molecular pathology diagnosis of dyschromatosis universalis hereditaria	5
Single‐cell analysis of human dermal fibroblasts isolated from a single male donor over 35 years	5
Biallelic mutations in LSS in autosomal‐recessive mutilating palmoplantar keratoderma	5
Molecular epidemiology of non‐syndromic autosomal recessive congenital ichthyosis in a Middle‐Eastern population	5
A viewpoint on the genetic determinants of generalised pustular psoriasis	5
Effectiveness and safety of reduced‐dose secukinumab switching to risankizumab for psoriasis patients in Asian population: A case series	5
Effects of metformin on experimentally induced acne on rabbit ear	5
Transcription factor YY1 contributes to human melanoma cell growth through modulating the p53 signalling pathway	5
Yin and Yang of skin microbiota in “swimmer acne”	5
Diversity in the clinical presentation of generalized pustular psoriasis (GPP): A series of case vignettes from around the world	5
CCL6 promotes M2 polarization and inhibits macrophage autophagy by activating PI3‐kinase/Akt signalling pathway during skin wound healing	5
miR‐24‐3p obstructs the proliferation and migration of human skin fibroblasts after thermal injury by targeting PPAR‐β and positively regulated by NF‐κB	5
Mechanism‐based therapeutic targets of pemphigus vulgaris: A scoping review of pathogenic molecular pathways	5
Comparative transcriptome analysis of acne vulgaris, rosacea, and hidradenitis suppurativa supports high‐dose dietary zinc as a therapeutic agent	5
Mutations within the putative protease domain of the human FAM111B gene may predict disease severity and poor prognosis: A review of POIKTMP cases	5
Dupilumab‐associated ocular adverse events are predicted by low tear break‐up time and correlate with high IL‐33 tear concentrations in patients with atopic dermatitis	5
Melatonin reduces melanogenesis by inhibiting the paracrine effects of keratinocytes	5
Two novel mutations of the γ‐secretase genes in Chinese acne inversa (hidradenitis suppurativa)	5