Xenotransplantation

Article	Citations
Hendrik Jan (Henk) Schuurman, MSc, PhD (1950–2024): In Memoriam	37
Systemic inflammation in the xenotransplant recipient (SIXR) can occur in the absence of pCMV infection	24
Impact of COVID‐19 Vaccination and Infection on Anti‐Triple‐Knockout (TKO) Pig Antibody Production: A Study in Patients With End‐Stage Liver Disease and Liver Transplant Recipients	23
Transthoracic echocardiography is a simple tool for size matching in cardiac xenotransplantation	22
Anti‐pig antibodies in swine veterinarian serum: Implications for clinical xenotransplantation	21
Anatomical and Physiological Considerations for Pig Cardiac Xenotransplantation	20
First transplantation of a pig heart from a multiple gene‐modified donor, porcine cytomegalovirus/roseolovirus, and antiviral drugs	19
Xenotransplantation Literature Update July–December 2024	18
A Review of Studies of Perfusion Storage of Pig Kidneys and Their Relevance to Clinical Xenotransplantation	17
Perspectives of Patients on the Kidney Transplant Waitlist Regarding Willingness to Undergo Xenotransplantation	17
Heterogenous expression of endocrine and progenitor cells within the neonatal porcine pancreatic lobes–Implications for neonatal porcine islet xenotransplantation	14
Issue Information	14
ECG Features in Orthotopic Cardiac Xenotransplantation: Comparisons With Published Literature	14
Issue Information	14
RETRACTION: An IgM Cleaving Enzyme for Clearance of Anti‐Pig Xenoreactive Antibodies in a Nonhuman Primate Model	14
Complement Inhibition in Xenotransplantation–Where Should the Complement Cascade be Inhibited?	13
Assessment of Porcine Endogenous Retrovirus Infectivity to Human Cells Using Flowcytometric Isolation After Co‐Culture	13
Xenotransplantation: A historical–ethical account of viewpoints	13
COVER IMAGE	13
Modified CD40L‐Activated B‐Cell Proliferation Model for Validating the Suppressive Activity of CD40‐CD154 Pathway Inhibitors	13
Religion and Attitudes Toward Xenotransplantation: Results of a Nationwide Survey in the United States	12
The case for the therapeutic use of mechanistic/mammalian target of rapamycin (mTOR) inhibitors in xenotransplantation	12
Xenotransplantation Literature Update December 2023–June 2024	12
Xenoreactive antibodies in α‐granules of human platelets bind pig liver endothelial cells	12
Xenotransplantation of pig islet cells: Potential adverse impact of virus infections on their functionality and insulin production	11

Organ xenotransplantation acceptance in veterinary students: A multicentric opinion study in Spain	11
Clinical Pig Kidney Xenotransplantation Rewrites the Rules of Renal Graft Rejection	10
Evaluation of Complement‐Dependent Cytotoxicity Assays for Gene‐Edited Pig‐to‐Human Xenotransplantation	10
Defect in Sensing Human Thrombin by Porcine Endothelial Protease‐Activated Receptor‐1: Molecular Incompatibility Between Porcine PAR‐1 and Human Thrombin	10
Xenotransplantation in the Age of Genome Editing: Results From the Expert Report for the Federal Ethics Committee on Nonhuman Biotechnology With a Special Focus on Animal Ethics	10
Global Research Trends and Current Status of Xenotransplantation: A Bibliometric Analysis	10
Issue Information	10
Observations on hydronephrosis after pig kidney transplantation in baboons	9
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Genetic diversity, growth and heart function of Auckland Island pigs, a potential source for organ xenotransplantation	9
Ethical Analysis of Voluntariness in Pig Kidney Xenotransplant First‐in‐Human Clinical Trials	9
Exploring attitudes toward xenotransplantation: A scoping review of healthcare workers, healthcare students, and kidney patients	9
Vatican Reaffirms Moral Permissibility of Xenotransplantation	8
Functional Xenogeneic Liver Support in a Living Human: Promise, Lessons, and Next Steps	8
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Comparative Inhibitory Effects of Tacrolimus, Cyclosporine, and Rapamycin on Human Anti‐Pig Xenogeneic Mixed Lymphocyte Reactions	8
Rural Transplant Disparities and Xenotransplantation: Scaling Is Not Enough	8
Donor‐Derived Cell‐Free DNA (dd‐cfDNA) as an Early Noninvasive Biomarker of Graft Injury in Pig‐to‐Monkey Islet Xenotransplantation	8
Xenotransplantation, Ethics, and Pediatric Decedent Studies	7
Pilot Survey of Attitudes Toward Xenotransplantation Among Nursing Students in London, UK	7
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Antibodies against hyaluronan oligosaccharides in xenotransplantation	7
A compositional analysis of native and decellularized porcine nasal septum cartilage	7
Porcine Cytomegalovirus/Porcine Roseolovirus (PCMV/PRV) and Antiviral Drugs	6
Antibody‐mediated rejection in xenotransplantation: Can it be prevented or reversed?	6
The impact of IdeS (imlifidase) on allo‐specific, xeno‐reactive, and protective antibodies in a sensitized rhesus macaque model	6
Genetic knockout of porcine GGTA1 or CMAH/GGTA1 is associated with the emergence of neo‐glycans	6
Methodological Approaches to Improve the Robustness of Bibliometric Studies in Xenotransplantation	6
Issue Information	6
International Xenotransplantation Association (IXA) Position Paper on the History, Current Status, and Regulation of Xenotransplantation	6
Humoral Barrier to Preclinical and Clinical Xenotransplantation	6
Harmonizing International Regulatory Standards for Porcine Endogenous Retrovirus (PERV) Screening in Genetically Modified Porcine Donors for First‐in‐Human Pancreatic Islet Xenotransplantation	6
Asking the Right Questions: Larry Faucette's Journey Through Xenotransplant	6
Historic progress in xenotransplantation with successful transplantation of genetically‐edited pig kidneys into living recipients	6
The Emergence of the Asian Xenotransplantation Association: Regional Collaboration in a Rapidly Evolving Field	6
Two‐day Static Cold Preservation of α1,3‐Galactosyltransferase Knockout Kidney Grafts Before Simulated Xenotransplantation	6
Large‐Scale Formation and Long‐Term Culture of Hepatocyte Organoids From Streamlined In Vivo Genome‐Edited GGTA1−/− Pigs for Bioartificial Liver Applications	6
RETRACTION: Combinatorial Decellularization as a Better Approach to Porcine Liver Extracellular Matrix Scaffold Fabrication with Preserved Bioactivity: A Comparative Evaluation	5
The International Human Xenotransplantation Inventory: Current Data and Future Directions	5
Alteration of γδ T cell subsets in non‐human primates transplanted with GGTA1 gene‐deficient porcine blood vessels	5
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Human CD64 Alleviates Antibody‐Mediated Rejection in Xenotransplantation	5
Sex Differences in Maturation and Function of Neonatal Porcine Islets Upon Transplantation in Mice	5
In Memoriam – Guy Alexandre (1934–2024)	5
In vivo induction of regulatory T cells by anti‐CD45RB antibody causes transferable tolerance to discordant human xenogenic islets	5
Governmental Questionnaire Survey on Adolescent and Young Adults’ Views on the Clinical Application of Xenotransplantation	5
Realistic Prospects of Xenotransplantation in Japan: Specific Regulations for Clinical Application	4
Renin‐Angiotensin‐Aldosterone System (RAAS) in Pig‐to‐Baboon Kidney Xenotransplantation—Relevance to Clinical Pig Kidney Xenotransplantation	4
Treatment of Presumptive Rejection After Orthotopic Pig‐to‐Baboon Cardiac Xenotransplantation	4
RETRACTION: Evaluation of Complement‐Dependent Cytotoxicity Assays for Gene‐Edited Pig‐to‐Human Xenotransplantation	4

Removal of Porcine Endogenous Retroviruses in Decellularized Liver Bioscaffolds	4
Author List	4
In Vitro Evaluation of Basiliximab as an Induction Therapy for Xenotransplantation	4
Xenotransplantation and Disability Contraindications to Pediatric Heart Transplantation: Are We at the Horizon of Organ Transplantation for any Person That May Benefit?	4
Xenotransplantation Literature Update: July–December 2025	4
Issue Information	4
The birth of Dolly and xenotransplantation 25 years on	4
Advances in Subclinical and Clinical Trials and Immunosuppressive Therapies in Xenotransplantation	4
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Views of Living Donor Liver Transplant Recipients About Xenotransplantation in Türkiye: A Qualitative Study	4
SARS‐CoV‐2 does not infect pigs, but this has to be verified regularly	4
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Xenotransplantation clinical trials: Should patients with diminished capacity be permitted to enroll?	4
Use of Brain Death Recipients in Xenotransplantation: A Double‐Edged Sword	4
Xenotransplantation at 30 years – A personal reminiscence and some thoughts for the future	4
How to Detect Porcine Endogenous Retrovirus (PERV) Infections in Patients After Transplantation of Pig Organs	4
Long‐term control of diabetes by tofacitinib‐based immunosuppressive regimen after allo islet transplantation in diabetic rhesus monkeys that rejected previously transplanted porcine islets	4
Cellular Landscapes of Different Gene‐Edited Pig Hearts Associated With Cardiac Xenotransplantation	3
International Xenotransplantation Association (IXA) Position Paper on Kidney Xenotransplantation	3
Integrated Multi‐Omics Analysis of Coagulation Dysregulation and Immune Pathway Alterations in 10‐Gene Pig‐to‐Monkey Liver Xenotransplantation: A Case Report	3
Issue Information	3
Noninvasive Monitoring of Complement Using the Bioluminescent Modified Ham Assay in the Second Porcine‐to‐Human Live Heart Transplant	3
Will Pig Organ Xenotransplantation in Patients Complicate the Use of Commonly Administered Drugs?	3
Expert opinion on the identification, risk assessment, and mitigation of microorganisms and parasites relevant to xenotransplantation products from pigs	3
Bridging Therapies—Ex Vivo Liver Xenoperfusion and the Role of Machine Perfusion: An Update	3
Clinical Xenotransplantation: A Suggested Next Step	3
Combinatorial Decellularization as a Better Approach to Porcine Liver Extracellular Matrix Scaffold Fabrication With Preserved Bioactivity: A Comparative Evaluation	3
“Will I Still be Myself?” Opposition to Xenotransplantation Among Chinese Kidney Transplant Candidates: A Qualitative Study	3
In Memoriam: Sir Roy Calne, FRCS, FRS, 1930–2024	3
CMAH‐Targeted Knock‐In of Inducible Heme Oxygenase‐1 and Constitutive CD47 in GGTA1‐Knockout Pigs for Xenotransplantation	3
Combined Islet and Kidney Xenotransplantation for Diabetic Nephropathy: Investigation of Pre‐Vascularized Composite Grafts versus Sequential Islet‐After‐Kidney Transplantation in a Pig‐to‐Nonhuman Pri	3
Knock‐out of N‐glycolylneuraminic acid attenuates antibody‐mediated rejection in xenogenically perfused porcine lungs	3
Which Platform of SARS‐CoV‐2 Vaccines Should be Used for Xenotransplant Recipients?	3
Public Attitudes Toward Xenotransplantation in South Korea: A 2023 Survey Study	3
Patient informed consent for a clinical trial of gene‐edited pig kidney transplantation: A representative consent form	3
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Molecular incompatibility between pig CD200 and human CD200 receptor in in vitro xenogeneic immune responses	2
Issue Information	2
Human or Not? An Experimental Investigation of Xenotransplantation Acceptability Across Donation Contexts	2
A murine groin site cardiac transplantation model—applicable tool for studying roles of peripheral lymph nodes in transplantation	2
Porcine cytomegalovirus/porcine roseolovirus (PCMV/PRV): A threat for xenotransplantation?	2
Attitudes Toward Renal Xenotransplantation in a Muslim Country: Analysis of Specific Subgroups	2
What's Hot and What's New in Xenotransplantation From the Young Investigator Committee of the IXA–Basic and Translational Science	2
Issue Information	2
An IgM Cleaving Enzyme for Clearance of Anti‐Pig Xenoreactive Antibodies in a Nonhuman Primate Model	2
Periodic Trajectories of the Plasma Metabolome in a Pig‐to‐Non‐Human Primate Cardiac Xenograft Model	2
Abstracts	2
Transplantation of porcine adrenal spheroids for the treatment of adrenal insufficiency	2
Xenotransplantation in China: Past, Present, and Future	2
Novel factors potentially initiating acute antibody‐mediated rejection in pig kidney xenografts despite an efficient immunosuppressive regimen	2
Liver Xenotransplantation: Ethical and Societal Implications	2
Evaluation of knowledge, attitude, and awareness of liver transplant patients toward xenotransplantation	2
Xenotransplantation literature update March 2023–November 2023	2
Anti–Non‐Gal Antibodies Against Porcine Protein Antigens as Barrier to Long‐Term Grafting of Xenografts in Humans	2
Quantitative Proteomic Analysis of Cardiac Xenograft Failure in a Pig‐to‐Non‐Human Primate Model Identifies NF‐κB as a Critical Immunomodulatory Target	2
Development and characterization of islet‐derived mesenchymal stem cells from clinical grade neonatal porcine cryopreserved islets	2
COVER IMAGE	2
Non‐Classical Swine Leukocyte Antigens SLA‐6, ‐7, and ‐8, Are Xenoantigens for Some Waitlisted Patients	2
Xenotransplantation Literature Update: January–June 2025	2
Assessment of glomerular filtration and tubular secretion in baboons with life‐supporting pig kidney grafts	1
Cellular Dynamics of Transgenic Porcine Endothelial Cells to Inflammatory Stimuli in Xenotransplantation Settings	1
Pilot Study: Functional Survival of Human Stem Cell‐Derived Islets Microencapsulated With Alginate Incorporating CXCL12 in Non‐Human Primates Without Systemic Immunosuppression	1
Issue Information	1
The Young Investigator Committee of the International Xenotransplantation Association—Perspective of advancements in the field in 2023	1
Issue Information	1
The Therapeutic Potential of Complement Inhibitors in Xenoreactive Human Complement‐Dependent Cytotoxicity in Vitro	1
Intensive Surveillance of Porcine‐Rhesus Kidney Xenotransplant Using Different Ultrasound Techniques	1
How Much Will a Pig Organ Transplant Cost? A Preliminary Estimate of the Cost of Xenotransplantation Versus Allotransplantation in the USA	1
RETRACTED: Combinatorial Decellularization as a Better Approach to Porcine Liver Extracellular Matrix Scaffold Fabrication With Preserved Bioactivity: A Comparative Evaluation	1
Investigational New Drug Enabling Nonclinical Study of Xenogeneic Life‐Supporting Porcine Kidneys With 10 Gene Edits (10 GE) in a Nonhuman Primate Test System	1
Close contacts of xenograft recipients: Ethical considerations due to risk of xenozoonosis	1
Short‐term function and immune‐protection of microencapsulated adult porcine islets with alginate incorporating CXCL12 in healthy and diabetic non‐human primates without systemic immune suppression: A	1
Current state of clinical trials on xenograft	1
The attitudes of religious group leaders towards xenotransplantation: A focus group study	1
Iscalimab Combined With Transient Tesidolumab Prolongs Survival in Pig‐to‐Rhesus Monkey Renal Xenografts	1
Mapping the Evolution of Solid Organ Xenotransplantation Research:A Systematic Review	1
Development of a panel for detection of pathogens in xenotransplantation donor pigs	1
Clinical Kidney Xenotransplantation—Why Do We Not Transplant Both Pig Kidneys Into the Recipient?	1
Public‐Facing Media Characterizations of Contemporary First‐in‐Human Xenotransplants in the United States: A Qualitative Content Analysis	1
Glycocalyx dynamics and the inflammatory response of genetically modified porcine endothelial cells	1

Religious Perspectives Regarding the Ethical Issues Associated With Clinical Xenotransplantation	1
Issue Information	1
Xenotransplantation and exotransplantation: Strategies to expand the number of donor organs	1
Early Experimental Report of the First 8‐Gene‐Edited Pig‐to‐Rhesus Macaque Cardiac Xenotransplantation in China	1
Large‐gap peripheral nerve repair using xenogeneic transplants in rhesus macaques	1
Characteristics Associated With Acceptance of Porcine Xenotransplantation	1
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Lessons learned from the first cardiac xenotransplant in a consciously consenting human: Psychiatric considerations and the impact of media exposure	1
Systemic inflammation in xenograft recipients (SIXR) or undetected PCMV/PRV transmission?	1
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Preservation of Cardiac Xenografts in a Model of Infant Human Cardiac Transplantation	1
Attitudes of patients with renal disease on xenotransplantation: A systematic review	1
Late graft failure of pig‐to‐rhesus renal xenografts has features of glomerulopathy and recipients have anti‐swine leukocyte antigen class I and class II antibodies	1
Assessing Knowledge, Attitudes, and Practices of Healthcare Workers in Saudi Arabia Towards Xenotransplantation: Insights From a Cross‐Sectional Survey	1
Construction and Validation of a Predictive Model for the Acceptance of Kidney Xenotransplantation by Medical Staff	1
Beyond the Transplanted: Who Should Inform Attitudes Toward Xenotransplantation?	1
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A Report of Four Depletional Induction Strategies in Non‐Human Primate Islet Xenotransplantation	1
Barriers toward xenotransplantation in Arab World	1