OOIR: Observatory of International Research

Papers

(The median citation count of Journal of Clinical Biochemistry and Nutrition is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Severe grade of melanosis coli is associated with a higher detection rate of colorectal adenoma	32
Effect of matcha consumption on gut microbiota in healthy Japanese individuals: study protocol for a double-blind crossover interventional study	27
The accumulation of copper in the brain of Down syndrome promotes oxidative stress: possible mechanism underlying cognitive impairment	18
The protective role of kakkalide in sepsis-induced intestinal barrier dysfunction via inhibition of NF-‍κB pathway activation	17
β-Elemene inhibits adipogenesis in 3T3-L1 cells by regulating AMPK pathway	16
Characterization of the gut phageome of Japanese patients with ulcerative colitis under endoscopic remission	14
Exploratory analysis of the association between dietary niacin intakes and nonalcoholic fatty liver disease among US adults: 1999–2018 data analysis from the National Health and Nutrition Examination	13
Cardiac robustness regulated by reactive sulfur species	12
Association between reactive oxygen species production in neutrophils and liver fibrosis in the general population	11
Acute exacerbation of idiopathic pulmonary fibrosis model by small amount of lipopolysaccharide in rats	11
Dietary Combination of Sucrose and Linoleic Acid Increases Intramyocellular Lipid and Impairs Muscle Strength in Female Zucker Diabetic Fatty Rats	11
Partially hydrolyzed guar gum ingestion suppresses atopic dermatitis-like symptoms through prebiotic effect in mice	11
Low-carbohydrate diets adversely impact the skin of a mouse model of photoaging exposed to ultraviolet B radiation	10
Successful endoscopic hemostasis compared to transarterial embolization in patients with colonic diverticular bleeding	9
Different associations of specific non-alcoholic beverages with elevated high-sensitivity C-reactive protein in Korean adults: results from the Korea National Health and Nutrition Examination Survey (	9
High poly-γ-glutamic acid-containing natto improves lipid metabolism and alters intestinal microbiota in mice fed a high-fat diet	9
Inhibition of lincRNA-Cox2 alleviates apoptosis and inflammatory injury of lipopolysaccharide-stimulated human bronchial epithelial cells via the Nrf2/HO-1 axis	9
25-hydroxyvitamin D-1α-hydroxylase (CYP27B1) induces ectopic calcification	9
Sodium salicylate and 5-aminosalicylic acid synergistically inhibit the growth of human colon cancer cells and mouse intestinal polyp-derived cells	8
Acute effect of proprotein convertase subtilisin/kexin type 9 inhibitor on oxidized low-density lipoprotein and lipid profile in patients at cardiovascular risk	8
Associations of circulating xanthine oxidoreductase activity with cardiometabolic risk markers in overweight and obese Japanese men: a cross-sectional pilot study	8
Effect of tocotrienol on the primary progression of nonalcoholic steatohepatitis in a mouse model	8
A randomized, double-blinded study evaluating effect of matcha green tea on human fecal microbiota	7
Microglial inflammatory reactions regulated by oxidative stress	7
Quenching effect of cerium oxide nanoparticles on singlet oxygen: validation of the potential for reaction with multiple reactive oxygen species	7

8-Nitro-cGMP suppresses mineralization by mouse osteoblasts	7
Relationship between critical care nutrition and post-intensive care syndrome in surviving ventilated patients with COVID-19: a multicenter prospective observational study	6
Effect of high-amylose rice “Hoshinishiki” on ‍postprandial glucose levels measured by ‍continuous glucose monitoring in patients with ‍diabetes	6
TRIM62 knockdown by inhibiting the TLR4/NF-κB pathway and NLRP3 inflammasome attenuates cognitive impairment induced by diabetes in mice	6
SMOC2 promoted vascular smooth muscle cell proliferation, migration, and extracellular matrix degradation by activating BMP/TGF‐β1 signaling pathway	6
Sirtuin 3 ameliorates inflammatory bowel disease via inhibiting intestinal inflammation and oxidative stress	6
The hypotaurine-taurine pathway as an antioxidative mechanism in patients with acute liver failure	6
Metabolic changes induced by TGF-β1 via reduced expression of phosphatidylserine decarboxylase during myofibroblast transition	6
Role of copper and SOD3-mediated extracellular redox regulation in tumor progression	6
Crosstalk between oxygen signaling and iron metabolism in renal interstitial fibroblasts	6
Application of regulation of reactive oxygen species and lipid peroxidation to disease treatment	6
Dose-dependent scavenging activity of the ultra-short-acting β1-blocker landiolol against specific free radicals	6
Edible bird’s nest extract downregulates epidermal apoptosis and helps reduce damage by ultraviolet radiation in skin of hairless mice	6
Vonoprazan vs lansoprazole for the treatment of artificial gastric ulcer after endoscopic submucosal dissection: a prospective randomized comparative study	5
Association between upper limb muscle quality and knee osteoarthritis in dynapenia: an observational cross-sectional study	5
Lipid-soluble polyphenols from sweet potato exert antitumor activity and enhance chemosensitivity in breast cancer	5
Rapid pretreatment for multi-sample analysis of advanced glycation end products and their role in nephropathy	5
Reduced abundance of butyric acid-producing bacteria in the ileal mucosa-associated microbiota of ulcerative colitis patients	5
A cross-sectional study on the relationship between nutrient/food intake and gut microbiota in frailty among older community residents: The Kyotango study	5
Low immunogenicity of vedolizumab determined by a simple drug-tolerant assay in patients with ulcerative colitis	5
Comparison of mucosa-associated microbiota in Crohn’s disease patients with and without anti-tumor necrosis factor-α therapy	4
Analysis of long-term serological and histological changes after eradication of <i>Helicobacter pylori</i>	4
Changes in plasma-concentration ratios of branched-chain amino acids in acute and convalescent phases of bacterial pneumonia	4
Development of sandwich ELISAs for detecting glucagon-like peptide-1 secretion from intestinal L-cells and their application in STC-1 cells and mice	4
The anti-inflammatory and protective role of interleukin-38 in inflammatory bowel disease	4
Genetic predicted causal inferences between antioxidants and birth weight	4
A nutritional intervention that promotes increased vegetable intake in Japanese with non-alcoholic fatty liver disease: a six-month trial	3
LC/MS/MS detection of uric acid oxidation metabolites to evaluate reactive oxygen and nitrogen species <i>in vivo</i> with application to pseudo-inflammation	3
Intensive, prolonged exercise seemingly causes gut dysbiosis in female endurance runners	3
Short-term intake of delta-tocotrienol on lipid profiles in healthy subjects	3
Long-lasting renal dysfunction following tacrolimus induction therapy in ulcerative colitis patients	3
Can bone mass measured via bioelectrical impedance analysis be used to diagnose sarcopenia?	3
Combined effects of granulocyte and monocyte adsorption apheresis and corticosteroids on ulcerative colitis	3
Characterized factors of subjects who were first time diagnosed as hyperglycemia more than 126 ‍mg/dl during annual or biannual medical checkups: a case-control study in Japan	3
Effects of additives on reaction of nucleosides with UV light in presence of uric acid and salicylic acid	3
FOXM1 transcriptionally activates NEIL3 to inhibit ferroptosis in lung adenocarcinoma cells	3
Newly developed evaluation for intestinal permeability using <i>Caenorhabditis elegans</i>: Protective effects of agaro-oligosaccharides on intestinal permeability	3
Eurycomanone from <i>Eurycoma longifolia</i> Jack upregulates neurotrophin-3 gene expression in ‍retinal Müller cells <i>in vitro</i>	3
Induction of mucosal healing by intensive granulocyte/monocyte adsorptive apheresis (GMA) without use of corticosteroids in patients with ulcerative colitis: long-term remission maintenance after indu	3
Induction of <i>MYCN</i>-amplified neuroblastoma differentiation through NMYC suppression using PPAR-γ antagonist	3
Relationships between body mass index and constipation, gastroesophageal reflux disease, stool forms based on the Bristol Stool Form Scale, and education level: results from an internet survey in Japa	3
Interaction between inorganic phosphate concentration and glucose metabolism in mild refeeding syndrome model	3
Association of urinary 8-hydroxydeoxyguanosine level with arteriosclerosis-related factors in ‍healthy, urban residents aged ≥50 years in ‍Japan	3
Comparison of the oxidative profiles before and after revascularization in peripheral arterial disease: a pilot study	3
Association between dyspeptic symptoms and endoscopic findings based on the Kyoto classification of gastritis in Japanese male	3
Association of alcohol intake and female gender with high expression of TMPRSS2 in tongue as potential risk for SARS-CoV-2 infection	3
Monascus pigment prevent the oxidative cytotoxicity in myotube derived hydrogen peroxide	3
Association of lysophosphatidic acid molecules with liver fibrosis: different roles indicated	3
Effect of folic acid supplementation on the change of plasma <i>S</i>-adenosylhomocysteine level in Chinese hypertensive patients: a randomized, double-blind, controlled clinical trial	3
5-<i>N</i>-Carboxyimino-6-aminopyrimidine-2,4(3<i>H</i>)-dione, a novel indicator for hypochlorite formation	2

Erratum	2
Confirmation of efficacy, elucidation of mechanism, and new search for indications of radon therapy	2
Protective effects of 2-aminoethylthiosulfuric acid and structurally analogous organosulfur compounds against ionizing radiation	2
Effects of ergothioneine on oxidative DNA damage and immune response induced by circadian rhythm disturbance in mice	2
A newly developed solution for the preservation of short-chain fatty acids, bile acids, and microbiota in fecal specimens	2
Combined fructose and sucrose consumption from an early age aggravates cardiac oxidative damage and causes a dilated cardiomyopathy in ‍SHR rats	2
Ethanol enhances selenoprotein P expression via ERK-FoxO3a axis in HepG2 cells	2
Redox state as assessed using the measurement of human non-mercaptalbumin in embryo culture media is associated with successful embryo development in human <i>in vitro</i> fertilization	2
Association between frailty and dietary quality in community-dwelling elderly: data from the 6th Korea National Health and Nutrition Examination Survey (2014–2015)	2
Linear association between aging and decreased blood thiol antioxidant activity in patients with cataract	2
Increased expression of ELOVL7 contributes to production of inflammatory cytokines in THP-1 cell-derived M1-like macrophages	2
8-prenylnaringenin suppresses obesity in high-fat diet-fed C57BL/6J mice via adiponectin secretion	2
The fetal gastrointestinal tract is exposed to melatonin and superoxide dismutase rich amniotic fluid throughout prenatal development	2
Retrospective investigation of mesalamine intolerance in patients with ulcerative colitis	2
Slowly progressive cell death induced by GPx4-deficiency occurs via MEK1/ERK2 activation as a downstream signal after iron-independent lipid peroxidation	2
Reactive oxygen species induced by indomethacin enhance accumulation of heme ‍carrier protein 1 and hematoporphyrin accumulation <i>in vitro</i> and <i>in vivo</i> in a brain t	2
Role of gut microbiota in inflammatory bowel disease pathogenesis	2
Reducing early pregnancy loss with vitamin D<sub>3</sub>: an analysis of serum 1,25-(OH)D<sub>3</sub> modulation and miscarriage risk	2
Regulation of type I IFN responses by deubiquitinating enzyme A in inflammatory bowel diseases	2
Nobiletin, a polymethoxylated flavonoid from citrus, enhances IL-4 production in DO11.10 mice via antigen-presenting cells	2
Plasma-activated medium exerts tumor-specific inhibitory effect on hepatocellular carcinoma via disruption of the salvage pathway	2
Pharmacokinetics and effect of maslinic acid with physical exercise on grip strength and trunk muscle mass in healthy Japanese individuals	2
The alteration of serum bile acid profile among traumatic brain injury patients: a small-scale prospective study	2
Introduction to serial reviews: Copper biology in health and disease	2
Serum titer of neutralizing antibodies after COVID-19 vaccination in Japanese patients with inflammatory bowel disease	2
Fermented rice bran supplementation ameliorates obesity via gut microbiota and metabolism modification in female mice	2
A pathological link between dysregulated copper binding in Cu/Zn-superoxide dismutase and amyotrophic lateral sclerosis	2
High-intensity exercise impairs intestinal barrier function by generating oxidative stress	2
Influence of vitamin D status on the variability of collagen I C-telopeptide in pre- and post-menopausal healthy women	2
Reactions of kynurenic acid with hypobromous acid and hypochlorous acid	2
Ischemia/reperfusion-associated oxidative stress is an aggravating factor for pressure ulcers	2
Resveratrol is converted to the ring portion of coenzyme Q10 and raises intracellular coenzyme Q10 levels in HepG2 cell	2
Impact of oligomeric enteral nutrition with low-molecular-weight whey peptides on diarrhea in critical care nutrition	2
Method for detecting CoQ10 incorporation in the mitochondrial respiratory chain supercomplex	2
Balance of the prooxidant and antioxidant system is associated with mortality in critically ill patients	2
<i>Streptococcus thermophilus</i> extends lifespan through activation of DAF-16-mediated antioxidant pathway in <i>Caenorhabditis elegans</i>	2
Crosstalk of copper and zinc in the pathogenesis of vascular dementia	2
Heat-killed <i>Lactococcus lactis</i> subsp. <i>lactis</i> L8 ameliorates dextran sulfate sodium-induced colitis in mice	1
Sebacic acid, a royal jelly-containing fatty acid, decreases LPS-induced IL-6 mRNA expression in ‍differentiated human THP-1 macrophage-like cells	1
D-Cysteine supplementation partially protects against ferroptosis induced by xCT dysfunction via increasing the availability of glutathione	1
<i>Trans</i>-resveratrol reduced hepatic oxidative stress in an animal model without inducing an ‍upregulation of nuclear factor erythroid 2-‍related factor 2	1
Single-cell analysis reveals islet autoantigen’s immune activation in type 1 diabetes patients	1
Oxidative stress induces tau hyperphosphorylation via MARK activation in neuroblastoma N1E-115 cells	1
The significance of CDT1 expression in non-cancerous and cancerous liver in cases with hepatocellular carcinoma	1
Optimizing vitamin supplementation via reference interval update of vitamins A, E, B1, and B6 using HPLC	1
Metabolomics analysis of amino acid and fatty acids in colorectal cancer patients based on tandem mass spectrometry	1
Mitochondrial stress and glycoxidation increase with decreased kidney function	1
Gut dysbiosis induced by a high-salt diet aggravates atherosclerosis by increasing the absorption of saturated fatty acids in ApoE-deficient mice	1
CREB1 regulates RECQL4 to inhibit mitophagy and promote esophageal cancer metastasis	1
Single oral administration of quercetin glycosides prevented acute hyperglycemia by ‍promoting GLUT4 translocation in skeletal muscles through the activation of AMPK in mice	1
TMEM189 as a target gene of MiR-499a-5p regulates breast cancer progression through the ferroptosis pathway	1
Metabolic mediators of the causal relationship between inflammatory bowel disease and allergic rhinitis: insights from Mendelian randomization	1
Availability of dietary secoisolariciresinol diglucoside on borderline blood cholesterol level in men: a randomized, parallel, controlled, double-blinded clinical trial	1
Fat-free oral nutritional supplements for patients after acute illness: a prospective observational study	1
Reciprocal regulation of protein arginine deiminase 2 and 4 expression in the colonic mucosa of ulcerative colitis	1
Innovative novel candy made from a low-solubility amorphous material promotes saliva secretion: a randomized, double-blind, placebo-controlled crossover comparative trial	1
Efficacy evaluation of upper gastrointestinal endoscopy screening for secondary prevention of gastric cancer using the standardized detection ratio during a medical check-up in ‍Japan	1
Miso, fermented soybean paste, suppresses high-fat/high-sucrose diet-induced muscle atrophy in mice	1
A mixed antioxidant supplement improves cognitive function, and coordination in aged mice	1
Theaflavins decrease skeletal muscle wasting in disuse atrophy induced by hindlimb suspension in mice	1
Singlet oxygen from endoperoxide initiates an intracellular reactive oxygen species release in HaCaT keratinocytes	1
Reduced prosaposin levels in HepG2 cells with long-term coenzyme Q10 deficiency	1
Knockdown of LRRK2 inhibits the progression of lung cancer by regulating TLR4/NF-κB pathways and NLRP3 inflammasome	1
Is nerve-directed stretching effective for improving of ankle joint flexibility and tissue stiffness in older men?	1
Soy isoflavone genistein attenuates the efficacy of immune checkpoint therapy in C57BL/6 mice inoculated with B16F1 melanoma and a high PD-‍L1 expression level reflects tumor resistance	1
Intragastric bacterial infection and endoscopic findings in <i>Helicobacter pylori</i>-negative patients	1
Dietary intervention of prebiotic partially hydrolyzed guar gum improves skin viscoelasticity, stratum corneum hydration, and ‍reduction of trans-epidermal water loss: a ‍randomized, double-blind, and	1
Increased salt intake is associated with diabetes and characteristic dietary habits: a community-based cross-sectional study in Japan	1
Effect of omega-3 fatty acids on sleep: a systematic review and meta-analysis of randomized controlled trials	1
Effects of luseogliflozin treatment on hyperglycemia-induced muscle atrophy in rats	1
Identification of miRNAs associated with eosinophilic esophagitis shown by esophageal mucosal biopsy results of Japanese patients	1
Dietary antioxidants and flavonoids intake, and their association with inflammation and oxidative stress parameters in asthmatic women: a case-control study	1
Oral supplementation of a cell preparation of <i>Enterococcus faecalis</i> strain EC-12 stimulates superoxide dismutase production in the livers of healthy and arthritis-induced mice	1
Andrographolide derivative CX-10 alleviates ulcerative colitis by modulating autophagy and cellular stress	1
Molecular mechanisms underlying the promotion of wound repair by coenzyme Q10: PI3K/Akt signal activation via alterations to cell membrane domains	1