OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Clinical Biochemistry and Nutrition is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
TRIM62 knockdown by inhibiting the TLR4/NF-κB pathway and NLRP3 inflammasome attenuates cognitive impairment induced by diabetes in mice	31
Sirtuin 3 ameliorates inflammatory bowel disease via inhibiting intestinal inflammation and oxidative stress	23
A cross-sectional study on the relationship between nutrient/food intake and gut microbiota in frailty among older community residents: The Kyotango study	20
The accumulation of copper in the brain of Down syndrome promotes oxidative stress: possible mechanism underlying cognitive impairment	18
Characterization of the gut phageome of Japanese patients with ulcerative colitis under endoscopic remission	14
Quenching effect of cerium oxide nanoparticles on singlet oxygen: validation of the potential for reaction with multiple reactive oxygen species	12
25-hydroxyvitamin D-1α-hydroxylase (CYP27B1) induces ectopic calcification	12
Development of sandwich ELISAs for detecting glucagon-like peptide-1 secretion from intestinal L-cells and their application in STC-1 cells and mice	12
Reduced abundance of butyric acid-producing bacteria in the ileal mucosa-associated microbiota of ulcerative colitis patients	11
The hypotaurine-taurine pathway as an antioxidative mechanism in patients with acute liver failure	11
The anti-inflammatory and protective role of interleukin-38 in inflammatory bowel disease	11
Relationships between body mass index and constipation, gastroesophageal reflux disease, stool forms based on the Bristol Stool Form Scale, and education level: results from an internet survey in Japa	10
Induction of <i>MYCN</i>-amplified neuroblastoma differentiation through NMYC suppression using PPAR-γ antagonist	10
Changes in plasma-concentration ratios of branched-chain amino acids in acute and convalescent phases of bacterial pneumonia	10
Effect of folic acid supplementation on the change of plasma <i>S</i>-adenosylhomocysteine level in Chinese hypertensive patients: a randomized, double-blind, controlled clinical trial	10
Association of alcohol intake and female gender with high expression of TMPRSS2 in tongue as potential risk for SARS-CoV-2 infection	9
Nobiletin, a polymethoxylated flavonoid from citrus, enhances IL-4 production in DO11.10 mice via antigen-presenting cells	9
Association of lysophosphatidic acid molecules with liver fibrosis: different roles indicated	9
8-Prenylnaringenin suppresses obesity in high-fat diet-fed C57BL/6J mice via adiponectin secretion	9
Newly developed evaluation for intestinal permeability using <i>Caenorhabditis elegans</i>: Protective effects of agaro-oligosaccharides on intestinal permeability	8
Comparison of the oxidative profiles before and after revascularization in peripheral arterial disease: a pilot study	8
A nutritional intervention that promotes increased vegetable intake in Japanese with non-alcoholic fatty liver disease: a six-month trial	8
Plasma-activated medium exerts tumor-specific inhibitory effect on hepatocellular carcinoma via disruption of the salvage pathway	8
Singlet oxygen from endoperoxide initiates an intracellular reactive oxygen species release in HaCaT keratinocytes	7
Balance of the prooxidant and antioxidant system is associated with mortality in critically ill patients	7

Stimulatory effects of collagen production induced by coenzyme Q<sub>10</sub> in cultured skin fibroblasts	7
LC/MS/MS detection of uric acid oxidation metabolites to evaluate reactive oxygen and nitrogen species <i>in vivo</i> with application to pseudo-inflammation	7
A mixed antioxidant supplement improves cognitive function, and coordination in aged mice	7
Intragastric bacterial infection and endoscopic findings in <i>Helicobacter pylori</i>-negative patients	7
Gut dysbiosis induced by a high-salt diet aggravates atherosclerosis by increasing the absorption of saturated fatty acids in ApoE-deficient mice	7
Linear association between aging and decreased blood thiol antioxidant activity in patients with cataract	7
Fat-free oral nutritional supplements for patients after acute illness: a prospective observational study	7
Treatment with broad-spectrum antibiotics upregulates Sglt1 and induces small intestinal villous hyperplasia in mice	7
Reduced prosaposin levels in HepG2 cells with long-term coenzyme Q10 deficiency	6
NEK7 inhibition attenuates Aβ<sub>42</sub>-induced cognitive impairment by regulating TLR4/NF-κB and the NLRP3 inflammasome in mice	6
Twendee X, a mixed antioxidant supplement, improves cognitive function, coordination, and neurotrophic factor expression in long-term vitamin E-deficient mice	6
Coenzyme Q10 levels increase with embryonic development in medaka	6
GPRC5A regulates proliferation and oxidative stress by inhibiting the STAT3/Socs3/c-‍MYC pathway in hepatocellular carcinoma	6
Analysis of serum zinc level in patients with severe trauma	6
Relative low muscle mass and muscle strength is associated with the prevalence of metabolic syndrome in patients with type 2 diabetes	6
Poricoic Acid A Inhibits Mitochondrial Dysfunction in Myocardial Infarction by Activating SIRT3	6
Edaravone, a scavenger for multiple reactive oxygen species, reacts with singlet oxygen to yield 2-oxo-3-(phenylhydrazono)-butanoic acid	6
Copper in the tumor microenvironment and tumor metastasis	5
Inhibition of ALA dehydratase activity in heme biosynthesis reduces cytoglobin expression which is related to the proliferation and viability of keloid fibroblasts	5
Modulations of the mTORC2–GATA3 axis by ‍an ‍isorhamnetin activated endosomal–lysosomal system of the J774.1 macrophage-like cell line	5
Involvement of α-klotho in growth hormone (GH) signaling	5
HIF1α/CCL7/KIAA1199 axis mediates hypoxia-induced gastric cancer aggravation and glycolysis alteration	5
Adiponectin Inhibits Chemokine-Induced Cell Migration via Direct Interaction with Platelet Factor 4	5
Enhancement of cytotoxic effects with ALA-PDT on treatment of radioresistant cancer cells	5
Evaluation of malnutrition by objective nutritional indexes and predictors in hospitalized patients with COVID-19	4
Application of regulation of reactive oxygen species and lipid peroxidation to disease treatment	4
FOXM1 transcriptionally activates NEIL3 to inhibit ferroptosis in lung adenocarcinoma cells	4
Dietary antioxidants and flavonoids intake, and their association with inflammation and oxidative stress parameters in asthmatic women: a case-control study	4
Association between upper limb muscle quality and knee osteoarthritis in dynapenia: an observational cross-sectional study	4
Background factors of idiopathic peptic ulcers and optimal treatment methods: a multicenter retrospective Japanese study	4
Sanguinarine attenuates hypoxia/reoxygenation-triggered H9c2 cell injury through activation of the Nrf2/NLRP3 pathway	4
Confirmation of efficacy, elucidation of mechanism, and new search for indications of radon therapy	4
Reducing early pregnancy loss with vitamin D<sub>3</sub>: an analysis of serum 1,25-(OH)D<sub>3</sub> modulation and miscarriage risk	4
Imaging analysis for multiple paramagnetic agents using OMRI and electrophoresis	4
High poly-γ-glutamic acid-containing natto improves lipid metabolism and alters intestinal microbiota in mice fed a high-fat diet	4
Effects of ergothioneine on oxidative DNA damage and immune response induced by circadian rhythm disturbance in mice	4
Optimizing vitamin supplementation via reference interval update of vitamins A, E, B1, and B6 using HPLC	4
Carotenoid transporter CD36 expression depends on hypoxia-inducible factor-1α in mouse soleus muscles	3
Improvement trend for individual health guidance intervention according to Japan clinical guidelines by public health nurses for type 2 diabetes mellitus who visited for medical checkups regularly: a	3
Risk factors and prediction of bleeding after gastric endoscopic submucosal dissection in patients on antithrombotic therapy: newly developed bleeding prediction application software, SAMURAI model	3
Letter to the Editor: Increased uric acid levels following fructose consumption: a biochemical perspective	3
Mechanisms of action of radon therapy on cytokine levels in normal mice and rheumatoid arthritis mouse model	3
Reduced phase angle as a potential indicator of mild cognitive impairment	3
Recent advances in copper analyses by inorganic mass spectrometry	3
Knockdown of LRRK2 inhibits the progression of lung cancer by regulating TLR4/NF-κB pathways and NLRP3 inflammasome	3
Relationship between serum pyridoxal 5'-‍phosphate concentration and cognitive function in older Japanese	3
Dietary intervention of prebiotic partially hydrolyzed guar gum improves skin viscoelasticity, stratum corneum hydration, and ‍reduction of trans-epidermal water loss: a ‍randomized, double-blind, and	3
Soy isoflavone genistein attenuates the efficacy of immune checkpoint therapy in C57BL/6 mice inoculated with B16F1 melanoma and a high PD-‍L1 expression level reflects tumor resistance	3
Effects of luseogliflozin treatment on hyperglycemia-induced muscle atrophy in rats	3
3-(4-Hydroxy-3-methoxyphenyl) propionic acid mitigates dexamethasone-induced muscle atrophy by attenuating Atrogin-1 and MuRF-1 expression in mouse C2C12 skeletal myotubes	3

Unique and overlapping roles of NRF2 and NRF1 in transcriptional regulation	3
Porphyromonas gingivalis lipopolysaccharide regulates cell proliferation, apoptosis, autophagy in esophageal squamous cell carcinoma via TLR4/MYD88/JNK pathway	3
Isolation of the hemeoxygenase-1 inducer from rice-derived peptide	3
Effect of fat ingestion on postprandial oxidative status in healthy young women: a pilot study	3
Iron as spirit of life to share under monopoly	3
Introduction to serial reviews: Copper biology in health and disease	3
Protective effects of liposomes encapsulating ferulic acid against CCl<sub>4</sub>-induced oxidative liver damage <i>in vivo</i> rat model	3
Crosstalk of copper and zinc in the pathogenesis of vascular dementia	3
Redox state as assessed using the measurement of human non-mercaptalbumin in embryo culture media is associated with successful embryo development in human <i>in vitro</i> fertilization	3
Increasing trend of <i>Helicobacter pylori</i>-uninfected gastric cancer without gastric atrophy	3
Acute effect of fructose, sucrose, and isomaltulose on uric acid metabolism in healthy participants	3
Vicious cycle of vitamin B<sub>1</sub> insufficiency and heart failure in cardiology outpatients	3
Investigation of the relationship between colonoscopy insertion difficulty factors and endoscope shape using an endoscopic position detection unit	3
Evaluation of cold atmospheric pressure plasma irradiation of water as a method of singlet oxygen generation	3
The association between serum zinc level and clinical features in patients with inflammatory bowel disease	3
Effective disruption of cancer cell membranes by photodynamic therapy with cell membrane-adhesive photosensitizer	3
A questionnaire-based survey on the etiopathogenesis of chronic constipation during a medical check-up in Japan	3
Andrographolide derivative CX-10 alleviates ulcerative colitis by modulating autophagy and cellular stress	3