Biological & Pharmaceutical Bulletin

Article	Citations
Genipin Attenuates Sepsis-Induced Splenocyte Apoptosis <i>via</i> the Inhibition of Endoplasmic Reticulum Stress	49
Dietary Zinc Deficiency Induces Ca<sub>v</sub>3.2-Dependent Nociceptive Hypersensitivity in Mice	39
Effect of Chronic Ethanol Consumption on Exogenous Glucose Metabolism in Rats Using [1-<sup>13</sup>C], [2-<sup>13</sup>C], and [3-<sup>13</sup>C]glucose Breath Tes	34
Sorghum (<i>Sorghum bicolor</i>) Extract-Induced Adipogenesis Is Independent of PPARγ Ser273 Phosphorylation in 3T3-L1 Adipocytes	29
Modeled Hepatic/Plasma Exposures of Omeprazole Prescribed Alone in Cytochrome P450 2C19 Poor Metabolizers Are Likely Associated with Hepatic Toxicity Reported in a Japanese Adverse Event Database	23
Characterization of Potentially Inappropriate Medications That Need Special Attention in the Elderly with Dementia by Analyzing Pharmacy Claims Data	23
Association between Weight Gain and Sex-Related Differences through 5-Fluorouracil Administration	23
Development of a Specific Competitive ELISA for Plasma Adropin Levels and Its Application to Investigating Energy Homeostasis in Mice	20
Comparison of Addition of Indications for Antineoplastic Agents Approved in the United States and Japan from 2001 to 2020	20
Protective Effect of Pemafibrate Treatment against Diabetic Retinopathy in Spontaneously Diabetic Torii Fatty Rats	18
Cross-Cancer Type Evaluation of Potential Interstitial Lung Disease Complications of Immune Checkpoint Inhibitors Using JADER	18
Russelioside A, a Pregnane Glycoside from <i>Caralluma tuberculate</i>, Inhibits Cell-Intrinsic NF-κB Activity and Metastatic Ability of Breast Cancer Cells	18
Novel Screening System for Biliary Excretion of Drugs Using Human Cholangiocyte Organoid Monolayers with Directional Drug Transport	18
Target Therapeutic Ranges of Anti-MRSA Drugs, Linezolid, Tedizolid and Daptomycin, and the Necessity of TDM	18
Development and Clinical Application of a Simultaneous Liquid Chromatography–Tandem Mass Spectrometry Method for Patients with Graft-versus-Host Disease to Quantify the Plasma Concentrations of Ruxoli	17
Pharmacological Characteristics of Extracellular Ca<sup>2+</sup> Influx Pathways Responsible for Platelet-Activating Factor-Induced Contractions in Rat Esophagus Smooth Muscle: Involvement	17
Vitamin K3 Suppresses Pyroptosis in THP-1 Cells through Inhibition of NF-κB and JNK Signaling Pathways	16
Changes in Pharmacy Students’ Awareness of Hepatitis B Patients through Patient Lectures as Humanity Education: Findings from Questionnaire Surveys of Face-to-Face and Simultaneous Remote Classes	16
Development of an Analytical Method for Unsaturated Disaccharides from Heparan Sulfate Using Dansylhydrazine Derivatization and High-Performance Liquid Chromatography with Fluorescence Detection	16
Chlorogenic Acid Inhibited Epithelial–Mesenchymal Transition to Treat Pulmonary Fibrosis through Modulating Autophagy	16
Role of P-Glycoprotein Expression and Scaffold Proteins in the Entire Metastasis Process in Lung Cancer Cell Lines	15
Effect of Amino Acid Substitution on Cell Adhesion Properties of Octa-arginine	15
New Directions for Advanced Targeting Strategies of EGFR Signaling in Cancer	14
Effect of Celecoxib Administration on the Skin of 40-Week-Old Mice	14
Identification and Physiological Analysis of Novel Riboflavin Transporter RFVT	14

Enhanced Anticancer Immunity Relieves Hypoxia in Tumors Treated with a Combination of Anti-PD-1 and Radiation Therapies	14
Impact of Drugs and Patient Characteristics on Life Expectancy during the Induction Phase of Dialysis	14
Population Pharmacokinetic Model of Amiodarone and <i>N</i>-Desethylamiodarone Focusing on Glucocorticoid and Inflammation	13
LncRNA <i>Gm16638-201</i> Inhibits the 14-3-3Ɛ Pathway in the Murine Prefrontal Cortex to Induce Depressive Behaviors	13
Amodiaquine Analogs Are Potent Inhibitors of Interleukin-6 Production Induced by Activation of Toll-Like Receptors Recognizing Pathogen Nucleic Acids	13
Shimanami Leaf Intake Affects Bowel Movement and Intestinal Microbiota in Mice	13
Pharmacological Investigation of Hypoalbuminemia on the Prolonged and Potentiated Action of Midazolam in Rats	13
Effect of PEGylated Liposomalization of Oxaliplatin on the Gut Microbiota in Mice	13
Magnitude of Fruit Juice–Drug Interactions Due to Osmolality-Dependent Fluid Secretion: Differences among Apple, Orange, and Grapefruit Juices	13
Process Optimization of Charge-Reversible Lipid Nanoparticles for Cytosolic Protein Delivery Using the Design-of-Experiment Approach	13
3′,4′-Dihydroxyflavonol Attenuates Lipopolysaccharide-Induced Neuroinflammatory Responses of Microglial Cells by Suppressing AKT–mTOR and NF-κB Pathways	13
RasGRP2 Attenuates TAGE Modification of eNOS in Vascular Endothelial Cells	13
Foreword	12
Kuanoniamine C Suppresses Adipogenesis and White Adipose Tissue Expansion by Modulating Mitochondrial Function	12
Foreword	12
Lymphatic Transport and Immune Activation Effect by Locally Administered Extracellular Vesicles from <i>Saccharomyces cerevisiae</i> as Biocompatible Vaccine Adjuvants	11
3-Nitropropionic Acid Enhances Ferroptotic Cell Death <i>via</i> NOX2-Mediated ROS Generation in STHdhQ111 Striatal Cells Carrying Mutant Huntingtin	11
Lipopolysaccharide Priming Exacerbates Anaphylatoxin C5a-Induced Anaphylaxis in Mice	11
Subsidy Programs for Herpes Zoster Vaccination in Japanese Municipalities	11
Evaluation of the Potential Inhibitory Effects of Medications for Detrusor Overactivity on Platelet-Activating Factor (PAF)-Induced Mechanical Activity in Guinea Pig Bladder Smooth Muscle	11
Usefulness of an Intermittently Scanned Continuous Glucose Monitoring System for Risk Management of Individuals without Diabetes in Japan	11
Cascade Enzyme Catalysis Supported Starvation and Photodynamic Synergistic Therapy for Breast Cancer	11
The Role of SGLT2 Inhibitor Ipragliflozin on Cardiac Hypertrophy and microRNA Expression Profiles in a Non-diabetic Rat Model of Cardiomyopathy	11
Chronic Treatment with Aβ42 with a Toxic Conformer and LPS Induces Inflammatory Responses in BV-2 Microglia with Dysregulation of Hypoxia-Inducible Factor Expression	11
Selective Inhibitory Effect of Hesperetin on the Automaticity of the Guinea Pig Pulmonary Vein Myocardium	11
Clozapine Induces Neuronal Activation in the Medial Prefrontal Cortex in a Projection Target-Biased Manner	11
Inhibition of p38 Mitogen-Activated Protein Kinases Attenuates Methylmercury Toxicity in SH-SY5Y Neuroblastoma Cells	11
A Reactive Metabolite of Clozapine Induces Hematopoietic Toxicity in HL-60 Cells Undergoing Granulocytic Differentiation through Its Effect on Glutathione Metabolism	11
Inhibition Mechanism of SARS-CoV-2 Infection by a Cholesterol Derivative, Nat-20(S)-yne	10
Detoxification and Activating Blood Circulation Decoction Promotes Reendothelialization of Damaged Blood Vessels <i>via</i> VEGF Signaling Pathway Activation by miRNA-126	10
Exploring Cell-Penetrating Peptides as Penetration Enhancers in Eye Drop Formulations Using a Reconstructed Human Corneal Epithelial Model	10
Establishment of Irinotecan-Induced Oral Mucositis Hamster Model and Evaluation of Therapeutic Agents	10
Effect of a Single Dose of Oxaliplatin on the Induction of Peripheral Neuropathy in a Rat Model: An <i>in Vivo</i> Electrophysiological Study	10
Dose Individualization of Oral Multi-Kinase Inhibitors for the Implementation of Therapeutic Drug Monitoring	10
Perineural Treatment with High Mobility Group Box-1 Monoclonal Antibody Prevents Initiation of Pain-Like Behaviors in Female Mice with Trigeminal Neuropathy	10
Intracerebroventricular Administration of Dermorphin-Dynorphin Analogs Producing Antidepressant-Like Effects through Activation of μ<sub>1</sub>- and κ-Opioid Receptors in Mice	10
Cryopreservation of Hepatocyte Organoid-Derived Cells Generated from Human iPS Cells	10
Innovative System for Delivering Nucleic Acids/Genes Based on Controlled Intracellular Trafficking as Well as Controlled Biodistribution for Nanomedicines	10
Effects of Antibacterial Agents on Cancerous Cell Proliferation	10
L-DOPA Receptor GPR143 Functionally Couples with Adrenergic α<sub>1B</sub> Receptor at the Second Transmembrane Interface	10
Dictamnine Ameliorates DNFB-Induced Atopic Dermatitis Like Skin Lesions in Mice by Inhibiting M1 Macrophage Polarization and Promoting Autophagy	9
Protective Effects of <i>Pleurotus</i> Species on UVB-Induced Skin Disorders at Clinically Relevant Plasma Concentrations of the Antioxidant Ergothioneine in Hairless Mice	9
Piperacillin Exacerbates Vancomycin-Induced Toxicity in Renal Proximal Tubular Cells	9
Cloperastine Reduces IL-6 Expression <i>via</i> Akt/GSK3/Nrf2 Signaling in Monocytes/Macrophages and Ameliorates Symptoms in a Mouse Sepsis Model Induced by Lipopolysaccharide	9
ELK3 Targeting AEG1 Promotes Migration and Invasion of Ovarian Cancer Cells under Hypoxia	9
Effective Location of the Plantar Surface of the Hind Paw for the Evaluation of Mechanical Hyperalgesia Using von Frey Filaments in Mice Treated with Paclitaxel	9
Association between Early Guanfacine Discontinuation and Somnolence for Attention-Deficit/Hyperactivity Disorder	9
Self-controlled Case Series Study for Acute Kidney Injury after Starting Proton Pump Inhibitors or Potassium-Competitive Acid Blocker in Patients with Cancer Using a Large Claims Database	9
Anacardic Acid Derivatives Isolated from Fungal Species <i>Tyromyces fissilis</i> as New Histone Acetyltransferase Inhibitors	9
Chronotropic and Inotropic Effects of Sudachitin, a Polymethoxyflavone from the Peel of <i>Citrus sudachi</i> on Isolated Rat Atria and Its Underlying Mechanisms	9

Antidepressant-Like Effects of Intracerebroventricular Injection of Nociceptin Analogs in Mice	9
Foreword	9
Prospective Analysis of Factors Influencing Inter-Individual Variation in Trough Plasma Voriconazole Concentrations in Older Patients—Impact of High <i>α</i>1-Acid Glycoprotein Levels	9
Deproteination of Serum–Drug Samples Utilizing a Temperature-Responsive Spin Column Containing Thermoresponsive Polymer Brush-Modified Beads	9
Influence of Size, Flexibility, Hydrophobicity, Surface Charge, and Surface Chemistry on the Biodistribution of Orally Administered Polymer Nanoparticles	9
Impact of Polypharmacy and Risk Factors for Exacerbation of Lower Urinary Tract Symptoms in Patients with Urological Conditions: A Retrospective Study in a Japanese Municipal Hospital	9
Platelets Affect the Activity of Amino Acid Transporter SNAT4 in HuH-7 Human Hepatoma Cells	9
Nrf2 Expression Is Decreased in LRRK2 Transgenic Mouse Brain and LRRK2 Overexpressing SH-SY5Y Cells	9
Clinical Analysis and <i>in Vitro</i> Correlation of BCRP-Mediated Drug–Drug Interaction in the Gastrointestinal Tract	9
Magnetic Delivery of Paclitaxel by Magnetic Anionic Liposome/Atelocollagen Complexes for Targeted Cancer Therapy	9
Role of the H19/miR-423-5p/DTX3L Axis in Enhancing the Malignant Phenotype of Nasopharyngeal Carcinoma Cells	9
Structural Perspective of the Double-Stranded RNA Transport Mechanism by SID-1 Family Proteins	9
Clinical Feasibility of Nomogram-Based Vancomycin Dosing Strategy: A Retrospective Study	9
Extracellular Vesicles Derived from the Serum of <i>Seriola quinqueradiata</i> Induce Human Umbilical Vein Endothelial Cell Proliferation through Angiogenic Signaling	9
A Novel Cross-Immune Antigen Vaccine Platform for Influenza Virus Type A	9
The Cyclin-Dependent Kinase 4/6 Inhibitor Abemaciclib Is Tolerated Better than Palbociclib by Advanced Breast Cancer Patients with High Serum Albumin Levels	8
Substrate-Dependent Alteration in the <i>C</i>- and <i>O</i>-Prenylation Specificities of <i>Cannabis</i> Prenyltransferase	8
Siweixizangmaoru Decoction Ameliorated Type II Collagen-Induced Arthritis in Rats <i>via</i> Regulating JAK2–STAT3 and NF-κB Signaling Pathway	8
Photoacoustic Imaging for Monitoring Calcium Dynamics in the Heart	8
Effect of Orally Ingested Water Containing H<sub>2</sub>-Filled Ultrafine Bubbles (UFBs) on Ethanol-Induced Oxidative Stress in Rats	8
RasGRP2 Attenuates Oxygen Deprivation-Induced Autophagy in Vascular Endothelial Cells	8
Qualitative Changes in Collagen Induced by UV Irradiation Affect Its Interaction with Cells	8
Structural and Functional Diversity of Mitochondria Isolated from Different Cell Types	8
Associations between Anticholinergic Use and Dementia Risk in a Prevalent-User Cohort: Analysis of Japanese Medication Histories as Real-World Data	8
Panobinostat, a Histone Deacetylase Inhibitor, Reduces LPS-Induced Expression of Inducible Nitric Oxide Synthase in Rat Immortalized Microglia HAPI Cells	8
The NAMPT Inhibitor FK866 Attenuates DEN-Induced Liver Fibrosis in Mice	8
Curcumin Is Primarily Distributed in Lung, Spleen and Liver, Metabolized to Glucuronide and Sulfate, and Excreted through Bile and Urine by Using an Amorphous Curcumin Formulation with High Absorbabil	8
Analysis of Risk Factors for Developing Tuberculosis in Patients Who Received Prophylactic Latent Tuberculosis Infection Treatment with Experience of Biologic Medications	8
Evaluation of Transport Activity Using Mouse Jejunal Epithelial Cell Monolayer Culture System	8
Phosphatidylcholine-Plasmalogen-Oleic Acid Has Protective Effects against Arachidonic Acid-Induced Cytotoxicity	8
Ginsenosides in <i>Panax ginseng</i> Extract Promote Anagen Transition by Suppressing BMP4 Expression and Promote Human Hair Growth by Stimulating Follicle-Cell Proliferation	8
Ganoderic Acid A Derived from Reishi Mushroom <i>Ganoderma lucidum</i> Protects against Intestinal Immunity Reduction Due to Oxidative Stress in Rat	8
Downregulation of Genes for Skeletal Muscle Extracellular Matrix Components by Cisplatin	8
Mogroside Alleviates Diabetes Mellitus and Modulates Intestinal Microflora in Type 2 Diabetic Mice	8
Quercetin, a Natural Dietary Flavonoid, Emerges a Novel USP7 Inhibitor with Anti-colorectal Cancer Effects	8
Andrographolide/Phospholipid/Cyclodextrin Complex-Loaded Nanoemulsion: Preparation, Optimization, <i>in Vitro</i> and <i>in Vivo</i> Evaluation	8
Seasonal Variations in Drug-Related Erythema Multiforme: A Time Series Analysis Using the JADER Database	8
Saikosaponin A Inhibits Growth of Human Bladder Carcinoma T24 and 5637 Cells Both <i>in Vitro</i> and <i>in Vivo</i>	8
Characterization of CNS Network Changes in Two Rodent Models of Chronic Pain	8
Carbon Monoxide Alleviates Post-ischemia–reperfusion Skeletal Muscle Injury and Systemic Inflammation	8
Ononin Relieves the Thyroid Cancer Progression through Targeting the Caspase 3 and CD274 Expression Levels	8
Mechanism of Human Cytomegalovirus-Induced Epithelial–Mesenchymal Transition in Glioma Cells <i>via</i> the Upregulation of RIP2 Expression	7
Ciclesonide Inhibits SARS-CoV-2 Papain-Like Protease <i>in Vitro</i>	7
The Potential Effects of 2,3,4-Trihydroxybenzophenone on the Transient Cerebral Ischemic Stroke in Male Mice	7
Longitudinal Trend in Antimicrobial Susceptibility among <i>Haemophilus influenzae</i>: A Single-Centre Study in Japan	7
Ameliorative Effects of Sweeteners on a Mouse Jet Lag Model	7
Emedastine Inhibits Th1 and Th2 Cell Differentiation Mediated by Mast Cells	7
Foreword	7
Risk Factors for Treatment Transition in Patients with Low-Risk Atrial Fibrillation Patients Undergoing Anticoagulation Monotherapy: A Large Claims Database Study in Japan	7
Assessment of Risk of Acidosis in Patients with Mild-to-Moderate Chronic Kidney Disease Treated with Intravenous Branched-Chain Amino Acid-Enriched Solution: A Propensity Score Matching Analysis	7
Study on the Protective Effect of Schizandrin B against Acetaminophen-Induced Cytotoxicity in Human Hepatocyte	7
New Drug Delivery Systems for Stable Oral Absorption: Theory, Strategies, and Applications	7
Development of siRNA Delivery System by Lipid Nanoparticles Modified with Functional Materials for Cancer Treatment	7
Visualization and Optical Manipulation of the Erectile Tissue, Penile Corpus Cavernous	7
Skin Dryness Induced in the KK-Ay/TaJcl Type 2 Diabetes Mouse Model Deteriorates Following Dapagliflozin Administration	7
Contamination-Free Milling of Ketoprofen Nanoparticles Using Mannitol Medium and Hoover Automatic Muller: Optimization of Effective Design of Experiment	7
The Mechanism of 5-Fluorouracil-Induced Hyperpigmentation in HRM-2 Hairless Mice: Focus on the Increase of Blood Vessels	7
Protective Effects of <i>Coptis chinensis</i> Rhizome Extract and Its Constituents (Berberine, Coptisine, and Palmatine) against α-Synuclein Neurotoxicity in Dopaminergic SH-SY5Y Cells	7
Probes with Tailored Pharmacokinetics for Radiotheranostics	7
Ketogenic Diet Alleviates Mechanical Allodynia in the Models of Inflammatory and Neuropathic Pain in Male Mice	7
Machine Learning-Based Model for Estimating Vancomycin Maintenance Dose to Target the Area under the Concentration Curve of 400–600 mg·h/L in Japanese Patients	7
Biochemical Characterizations of the Putative Amidase Endolysin Ecd18980 Catalytic Domain from <i>Clostridioides difficile</i>	7
Endogenous SOLOIST/MRTFB i4, a Neuronal Isoform of MKL2/MRTFB, Positively and Negatively Regulates SRF Target Immediate Early Genes in Neuro-2a Cells	7
Point Mutation Analysis of the Drug Efflux Pump MexB in Clinical Isolates of <i>Pseudomonas aeruginosa</i>	7
Efficacy of Zinc Acetate in the Treatment of Zinc Deficiency in Elderly Inpatients and Effect of Total Dose on Its Replacement Therapy	6
Biotransformation of Morphinone and Its Glutathione Adduct Derived from Morphine by Anaerobic Gut Microbes in Guinea Pigs	6
Induction of Melanin Synthesis by <i>Pueraria lobata</i> Leaves in B16 Murine Melanoma Cells and Three-Dimensional Human Skin Equivalent	6
Qualification of <i>In Vitro</i> Dissolution Absorption System 2 (IDAS2) with Caco-2 and MDCK Cell Monolayers: Dose Sensitivity Study Using BCS Class I and III Drugs	6
Assessment of Diagnosis Timing of Attention-Deficit/Hyperactivity Disorder in Working-Age Workers with Psychiatric Diseases Using Large Claims Data	6
Transcriptional Mechanism of the Mouse β4-Galactosyltransferase 6 Gene in Mouse Neuroblastoma Cell Line Neuro-2a	6
Structural Impact Assessment of Cytochrome P450 2A13 Polymorphisms Using Molecular Dynamics Simulations	6
Phospholipid Scramblase 1 Localizes Proximal to Sphingomyelin Synthase Isoforms but Is Not Involved in Sphingomyelin Synthesis	6
Transporters for Creatine and Related Guanidino Compounds: Their Relevance to Brain Health and Disorders	6
Analysis of Risk Factors for Infusion-Related Reactions Following Rituximab Administration in Patients with Desensitization before Renal Transplantation	6
A Complex of Type I Platelet-Activating Factor Acetylhydrolase (PAF-AH) Catalytic Subunits Switches from α1/α2 Heterodimer to α2/α2 Homodimer during Adipocyte Differentiation of 3T3-L1 Cells	6
Inhibitory Actions of Antidepressants, Hypnotics, and Anxiolytics on Recombinant Human Acetylcholinesterase Activity	6
Risk Assessment for Heart Failure in Patients with Type 2 Diabetes Mellitus Treated with Dipeptidyl Peptidase 4 Inhibitor Using a Large Claims Dataset	6
Removal of Soluble ACE2 in VeroE6 Cells by 17β-Estradiol Reduces SARS-CoV-2 Infectivity	6
Medical Economic Benefit Derived from the Use of Tracing Reports by Pharmacy-Based Pharmacists for Pharmaceutical Intervention and Reduction of Leftover Medicines	6
Renal Metabolomics Study and Critical Pathway Validation of Shenkang Injection in the Treatment of Chronic Renal Failure	6

Astrocytic Responses to Binge Alcohol Intake in the Mouse Hindbrain	6
Characterization of Novel Cell-Adhesive Peptides for Biomaterial Development	6
Goji Berry Juice Prevents Tumor Necrosis Factor Alpha-Induced Xerostomia in Human Salivary Gland Cells	6
Modeled Rat Hepatic and Plasma Concentrations of Chemicals after Virtual Administrations Using Two Sets of <i>in Silico</i> Liver-to-Plasma Partition Coefficients	6
Clinical Profiles of Japanese Patients with Stevens–Johnson Syndrome/Toxic Epidermal Necrolysis Collected by a Nationwide System from 2006 to 2023	6
SRF and SRF Cofactor mRNA Expression Is Differentially Regulated by BDNF Stimulation in Cortical Neurons	6
Prevention of Renal Interstitial Fibrosis by Suplatast in a Mouse Model	6
Aniseed, Caraway, and Cumin: Appetite-Enhancing Effects and Identification of Active Compounds	6
Effects of Body Composition on Renal Function Estimates in Older Patients	6
Curculigoside Represses the Proliferation and Metastasis of Osteosarcoma <i>via</i> the JAK/STAT and NF-κB Signaling Pathways	6
Functional Analysis of Modified Caco-2 Cells Carrying CES2A1 as a Model for Intestinal Absorption of Prodrugs	6
Usefulness of the Albumin–Bilirubin Score in Determining the Initial Dose of Voriconazole for Patients with Liver Cirrhosis	6
Blocking CXC Motif Chemokine Ligand 2 Ameliorates Diabetic Peripheral Neuropathy <i>via</i> Inhibiting Apoptosis and NLRP3 Inflammasome Activation	6
Inhibitory Effects of Lansoprazole and Omeprazole on the CYP2C19-Mediated Metabolism of Arachidonic Acid to Epoxyeicosatrienoic Acids: Implications for Cardiovascular Risk	6
HPLC–UV Analysis of Fruquintinib in Plasma of a Patient with Colorectal Cancer	6
Effects of Ingested Water Volume on Oral Absorption of Fenofibrate, a BCS Class II Drug, from Micronized and Amorphous Solid Dispersion Formulations in Rats	6
Feasibility Study of Dendrimer-Based TTR-CRISPR pDNA Polyplex for Ocular Amyloidosis <i>in Vitro</i>	6
A Survey of Near-Miss Dispensing Errors in Hospital Pharmacies in Japan: DEPP-J Study—Multi-Center Prospective Observational Study—	6
BET Inhibitors Induce p53-Independent Growth Arrest in HCT116 Cells <i>via</i> Epigenetic Control of the E2F1/c-<i>MYC</i> Axis	6
Anticancer Effects of New Disulfiram Analogs	6
Solubilizing Effect of Caffeine on Precipitate of Risperidone Oral Solution and Tea Beverage	6
Quetiapine Reverses the Behavior and Myelination in Alcohol-Exposed Gestational Diabetes Mellitus Offspring Mice <i>via</i> ERK1/2 Signaling	6
A Novel Lithocholic Acid Derivative Upregulates Detoxification-Related Genes in Human Induced Pluripotent Stem Cell-Derived Intestinal Organoids	6
Rapid Screening Detection of Genetically Modified Papaya by Loop-Mediated Isothermal Amplification	6
Serum Concentrations of Infliximab and IL-6 for Predicting One-Year Discontinuation of Infliximab Treatment Owing to Secondary Non-response in Patients with Rheumatoid Arthritis	6
Impact of Bridged Nucleic Acid Positions within Blocking Oligonucleotides on DNA Amplification Inhibition in Wild-Type Blocking PCR	6
Foreword	6
<i>Ajania purpurea</i> Extract Attenuates LPS-Induced Inflammation in RAW264.7 Cells and Peritonitis Mice	6
Development of a Nanocarrier-Based Splenic B Cell-Targeting System for Loading Antigens <i>in Vitro</i>	6
Liver and Plasma Concentrations of Food Chemicals after Virtual Oral Doses Extrapolated Using <i>in Silico</i> Estimated Input Pharmacokinetic Parameters to Confirm Reported Liver Toxicity	6
Fabrication of 3D-Printed Contact Lens Composed of Polyethylene Glycol Diacrylate for Controlled Release of Azithromycin	6
Pinpoint Insertion of a Single Amino Acid into a Framework Region Enhanced the Affinity of an Anti-cortisol Antibody to Enable Sensitive Immunoassays	6
Selexipag Improves Lipopolysaccharide-Induced ARDS on C57BL/6 Mice by Modulating the cAMP/PKA and cAMP/Epac1 Signaling Pathways	6
Evaluation of Puberulic Acid-Induced Nephrotoxicity Using 3D-RPTEC	6
Differences in the Inhibitory Effects of a Hydrophobic Skin Protectant on Maceration between Aged and Young Skin	5
Royal Jelly Maintains Epidermal Stem Cell Properties by Repressing Senescence	5
Enhanced Type I Collagen Synthesis in Fibroblasts by Dermal Stem/Progenitor Cell-Derived Exosomes	5
Quantitative Assessment of the Post-translational Modifications of Human Serum Albumin by Dimethyl Trisulfide	5
Development of a Highly Sensitive and Rapid Liquid Chromatography–Tandem Mass Spectrometric Method Using a Basic Mobile Phase Additive to Determine the Characteristics of the Urinary Metabolites for N	5
Combination Therapy with Betamethasone and Josamycin Demonstrates Superior Therapeutic Efficacy in an NC/Nga Mouse Model of Atopic Dermatitis	5
Protective Effect of Salidroside on Acute Kidney Injury in Sepsis by Inhibiting Oxidative Stress, Mitochondrial Damage, and Cell Apoptosis	5
Anti-atrial Fibrillatory Effects of the TRPC3 Channel Inhibitor Pyrazole-3 in Rats with Atrial Enlargement Induced by Chronic Volume Overload	5
Nanaomycin K Inhibited Cell Proliferation and Epithelial–Mesenchymal Transition in Renal Cell Carcinoma	5
The Involvement of HYBID in the Regulation of Intraocular Pressure and Extracellular Matrix Accumulation in the Trabecular Meshwork	5
Effects of Concomitant Administration of PXR Ligand Drugs on the Anticoagulant Effects of Warfarin	5
Upregulated ClC3 Channels/Transporters Elicit Swelling-Activated Cl<sup>−</sup> Currents and Induce Excessive Cell Proliferation in Idiopathic Pulmonary Arterial Hypertension	5
Quiescent B Cells Acquire Sensitivity to Cell Cycle Arresting Agents by B Cell Receptor Stimulation	5
Rapid Screening for Detecting Genetically Modified Wheat by Loop-Mediated Isothermal Amplification	5
Effect of Syk Inhibitory Activity of Vialinin A on Degranulation from Antigen-Stimulated RBL-2H3 Cells	5
Extravasation of Noncytotoxic Agents: Skin Injury and Risk Classification	5
Differential Effects of Gq Protein-Coupled Uridine Receptor Stimulation on IL-8 Production in 1321N1 Human Astrocytoma Cells	5
Possible Involvement of DNA Methylation and Protective Effect of Zebularine on Neuronal Cell Death after Glutamate Excitotoxity	5
Updated <i>in Silico</i> Prediction Methods for Fractions Absorbed and Key Input Parameters of 355 Disparate Chemicals for Physiologically Based Pharmacokinetic Models for Time-Dependent P	5
Analysis of Appendicitis Cases in the Japanese Adverse Drug Event Report (JADER) Database	5
Wogonin Attenuates Bleomycin-Induced Pulmonary Fibrosis and Oxidative Stress Injury <i>via</i> the MAPK Signaling Pathway	5
Schisandrin A Suppresses Guinea Pig Ileal Longitudinal Smooth Muscle Contraction through Functional Inhibition of L-Type Ca<sup>2+</sup> Channels	5
Proteasome Inhibition Induces IRF1 Downstream Molecules Independently of JAK Activity in Cancers	5
Efficacy of Enhanced Antimicrobial Stewardship Team Interventions for Patients Receiving Meropenem and Tazobactam/Piperacillin	5
Calculation of Human Melatonin Partial Metabolic Clearance in Healthy Adult Volunteers for Investigation of a Novel <i>in Vivo</i> CYP1A2 Phenotyping Method: A Pilot Study	5
The Tumor Microenvironment Remodeled by Epstein–Barr Virus: From Primary Site to Distant Metastatic Niche	5
Expression of the Discoidin Domain Receptor Family Depended on Glucose and Their High Expression in Arterial Tissues in the Rat Model of Type 2 Diabetes	5
The Effects of Jabara Juice on the Intestinal Permeation of Fexofenadine	5
Efficacy of Naldemedine on Intestinal Hypomotility and Adhesions in Rodent Models of Postoperative Ileus	5
Spasmolytic Effect of Flopropione Does Not Involve Catechol-<i>O</i>- methyltransferase (COMT) Inhibition	5
Research Progress in Drug Development Based on Functional Molecules Involved in Pathogenesis and Analysis of Their Mechanisms	5
Deficiency of Group IVA Phospholipase A<sub>2</sub> in Collagen-Producing Cells Alleviates the Aggravated Hepatic Fibrosis in High-Fat Diet-Fed Mice after Returning to a Normal Diet	5
Detection of Characteristic Phosphatidylcholine Containing Very Long Chain Fatty Acids in Cerebrospinal Fluid from Patients with X-Linked Adrenoleukodystrophy	5
Influence of Voiced and Semi-voiced Sounds on the Subjective Similarity of Different Drug Names: A Cognitive Psychological Experiment	5
Gambogenic Acid Inhibits Invasion and Metastasis of Melanoma through Regulation of lncRNA MEG3	5
Uniform Suspension of Heat-Killed <i>Staphylococcus aureus</i> for a Positive Control Used in the Monocyte-Activation Test	5
New Maintenance Culture Method for Intestinal Stem Cells Derived from Human Induced Pluripotent Stem Cells	5
Economic Cost of the Waste of Anti-inflammatory and Analgesic Drugs in Mexico City	5
Calsequestrin-1 Deficiency Induced Malignant Hyperthermia-Like Skeletal Injury through Mitochondrial Disorder	5
Suppression of Lipopolysaccharide-Induced IL-1β Gene Expression by High-Molecular-Weight Adiponectin in RAW264.7 Macrophages	5
Pharmacological Studies on the Ca<sup>2+</sup> Influx Pathways in Platelet-Activating Factor (PAF)-Induced Mouse Urinary Bladder Smooth Muscle Contraction	5
Proton Pumping ATPases: Rotational Catalysis, Physiological Roles in Oral Pathogenic Bacteria, and Inhibitors	5
Non-canonical Activation of RSK1 Induces EphA2-Mediated Cell Migration under Cellular Stress Conditions	5
Non-neuronal Cholinergic Muscarinic Acetylcholine Receptors in the Regulation of Immune Function	5
Therapeutic Drug Monitoring of Antibody Drugs	5
Effect of Growth Hormone Receptor Deficiency on Androgen-Associated Gene Expression of Hepatic Drug Metabolizing Enzymes and Drug Transporters in Pigs	5
Evaluating the Associated Hyperuricemia Risk with Sodium-Glucose Cotransporter 2 Inhibitors: A Sequence Symmetry Analysis Using the Japanese Administrative Claims Database	5
Notice of Addendum for Biological and Pharmaceutical Bulletin	5
Decreased Analgesic Effect of Tramadol in Japanese Patients with CYP2D6 Intermediate Metabolizers after Orthopedic Surgery	5
Ca<sup>2+</sup> Signaling and Proliferation <i>via</i> Ca<sup>2+</sup>-Sensing Receptors in Human Hepatic Stellate LX-2 Cells	5
Simple Cytosolic and Nuclear Introduction of Boron Compounds Using Cationic Lipids to Enhance Cancer Cell-Killing Activity in Boron Neutron Capture Therapy	5
Polygalacin D Prevents Breast Cancer Progression through Proteasome-Mediated Degradation of HDAC1 and HDAC2	5
Comparison of the Effectiveness of Vedolizumab and Ustekinumab in Crohn’s Disease Patients Who Failed Anti-tumor Necrosis Factor-α Treatment in Japan: An Observational Study Utilizing Claims Database	5
Predicting the Safety of Ocular Iontophoresis Using Reconstructed Human Corneal Epithelial Cells	5
Purification of Emu IgY for Therapeutic and Diagnostic Use Based on Monoclonal Secondary Antibodies Specific to Emu IgY	5
Regulation of Chloride Channels by Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitor-Induced α-Defensin 5	5
Impact of Daily High Ergosterol Intake for 14 Weeks in Ovariectomized Rats on Cholesterol and Vitamin D<sub>3</sub> Biosynthesis Pathways	5
Association between Inhalation Instruction Method in Community Pharmacies and Inhaler Device Handling Error in Patients with Obstructive Lung Disease: An Evaluation of the Impact of Practical Demonstr	5
Activation of the Keap1/Nrf2 Pathway as an Adaptive Response to an Electrophilic Metabolite of Morphine	5
Identification of Inhibitors for eIF5A2-Dependent Translation Elongation by Monitoring the Translational Efficiency of Polyproline Motif in Mitochondrial Fission Regulator 1	5
Platelet-Activating Factor (PAF) Induces Strong Mechanical Activities Accompanied by Basal Tension Increases in Esophageal and Gastric Fundus Smooth Muscles from Rat	5