Epilepsy Research

Article	Citations
Ketogenic diet and Neuroinflammation	86
A review of the drug−drug interactions of the antiepileptic drug brivaracetam	35
Network of depression and anxiety symptoms in patients with epilepsy	35
A phase 1b/2a study of soticlestat as adjunctive therapy in participants with developmental and/or epileptic encephalopathies	31
Time courses of HMGB1 and other inflammatory markers after generalized convulsive seizures	29
Ketogenic diet, neuroprotection, and antiepileptogenesis	28
A prospective multicenter study of laser ablation for drug resistant epilepsy – One year outcomes	27
A comparison of the gut microbiota among adult patients with drug-responsive and drug-resistant epilepsy: An exploratory study	26
Cannabidiolic acid exhibits entourage-like improvements of anticonvulsant activity in an acute rat model of seizures	24
Telemedicine and epilepsy: A patient satisfaction survey of a pediatric remote care program	23
Patterns of seizure spread in temporal lobe epilepsy are associated with distinct white matter tracts	23
Exploring quality of life in individuals with a severe developmental and epileptic encephalopathy, CDKL5 Deficiency Disorder	23
The ketogenic diet all grown up—Ketogenic diet therapies for adults	23
Genotype-phenotype correlates of infantile-onset developmental & epileptic encephalopathy syndromes in South India: A single centre experience	22
Individualizing the definition of seizure clusters based on temporal clustering analysis	22
Clinical pharmacokinetic and pharmacodynamic profile of midazolam nasal spray	20
Computational characteristics of interictal EEG as objective markers of epileptic spasms	20
Serotonin 5-HT4 receptors play a critical role in the action of fenfluramine to block seizure-induced sudden death in a mouse model of SUDEP	20
Expression of circulating microRNAs as predictors of diagnosis and surgical outcome in patients with mesial temporal lobe epilepsy with hippocampal sclerosis	19
NUS1 mutation in a family with epilepsy, cerebellar ataxia, and tremor	19
Association of HLA genotypes with phenytoin induced severe cutaneous adverse drug reactions in Thai children	19
Management of COVID-19 in patients with seizures: Mechanisms of action of potential COVID-19 drug treatments and consideration for potential drug-drug interactions with anti-seizure medications	19
Inhibitory effect of anti-seizure medications on ionotropic glutamate receptors: special focus on AMPA receptor subunits	18
Juvenile myoclonic epilepsy shows increased posterior theta, and reduced sensorimotor beta resting connectivity	18
Magnetic resonance–guided laser interstitial thermal therapy versus stereoelectroencephalography-guided radiofrequency thermocoagulation for drug-resistant epilepsy: A systematic review and meta-analy	18

Efficacy of low glycemic index diet therapy (LGIT) in children aged 2–8 years with drug-resistant epilepsy: A randomized controlled trial	18
Accuracy of ICD-10-CM claims-based definitions for epilepsy and seizure type	18
The role of inflammatory mediators in epilepsy: Focus on developmental and epileptic encephalopathies and therapeutic implications	17
Long-term epilepsy control, motor function, cognition, sleep and quality of life in children with West syndrome	17
Delays and disparities in diagnosis for adults with epilepsy: Findings from U.S. Medicaid data	17
Long-term outcomes of ketogenic diet in patients with tuberous sclerosis complex-derived epilepsy	17
A reliable interictal EEG grading scale for children with infantile spasms – The 2021 BASED score	17
Validating the accuracy of administrative healthcare data identifying epilepsy in deceased adults: A Scottish data linkage study	16
Prolactin levels as a criterion to differentiate between psychogenic non-epileptic seizures and epileptic seizures: A systematic review	16
Natural variability in seizure frequency: Implications for trials and placebo	16
A unifying mechanism of ketogenic diet action: The multiple roles of nicotinamide adenine dinucleotide	16
Digital tools for epilepsy: Opportunities and barriers	16
SP1 activated-lncRNA SNHG1 mediates the development of epilepsy via miR-154-5p/TLR5 axis	16
Correlates of depression and quality of life among patients with epilepsy in Nigeria	15
Management of West syndrome during COVID-19 pandemic: A viewpoint from South Asian West Syndrome Research Group	15
Persistent racial and ethnic disparities as a potential source of epilepsy surgery underutilization: Analysis of large national datasets from 2006–2016	15
The ketogenic diet for infants: How long can you go?	15
Dravet syndrome in children—A population-based study	15
Generator replacement with cardiac-based VNS device in children with drug-resistant epilepsy: An observational study	15
Graph theory application with functional connectivity to distinguish left from right temporal lobe epilepsy	14
CSF high-mobility group box 1 is associated with drug-resistance and symptomatic etiology in adult patients with epilepsy	14
Testing broad-spectrum and isoform-preferring HCN channel blockers for anticonvulsant properties in mice	14
Dravet syndrome: Advances in etiology, clinical presentation, and treatment	14
Deciphering the premature mortality in PIGA-CDG – An untold story	14
Control of drop attacks with selective posterior callosotomy: Anatomical and prognostic data	14
Long-term safety and effectiveness of stiripentol in patients with Dravet syndrome: Interim report of a post-marketing surveillance study in Japan	14
Effectiveness and tolerability of adjunctive brivaracetam in patients with focal seizures: Second interim analysis of 6-month data from a prospective observational study in Europe	14
Gut microbiota modulation by both Lactobacillus fermentum MSK 408 and ketogenic diet in a murine model of pentylenetetrazole-induced acute seizure	14
Efficacy of adjunctive cenobamate based on number of concomitant antiseizure medications, seizure frequency, and epilepsy duration at baseline: A post-hoc analysis of a randomized clinical study	13
Pattern analysis of glucose metabolic brain data for lateralization of MRI-negative temporal lobe epilepsy	13
The impact of Scn1a deficiency and ketogenic diet on the intestinal microbiome: A study in a genetic Dravet mouse model	13
A systematic review of seizure clusters: Prevalence, risk factors, burden of disease and treatment patterns	13
Spatiotemporal distribution and age of seizure onset in a pediatric epilepsy surgery cohort with cortical dysplasia	13
An integrative method to quantitatively detect nocturnal motor seizures	13
Long-term effectiveness and adverse effects of ketogenic diet therapy in infants with drug-resistant epilepsy treated at a single center in Argentina	13
An evaluation of the diagnostic equivalence of 18F-FDG-PET between hybrid PET/MRI and PET/CT in drug-resistant epilepsy: A pilot study	13
Epilepsy duration as an independent predictor of response to vagus nerve stimulation	12
Spike-Wave Index Assessment and Electro-Clinical Correlation in Patients with Encephalopathy Associated with Epileptic State During Slow Sleep (ESES / CSWS); Single-Center Experience	12
Trends of anti-seizure medication use in pediatric patients in six cities in China from 2013 to 2018	12
The evolving indications of KD therapy	12
Knowledge atlas of post-traumatic epilepsy research: Based on citespace visualization analysis	12
Determination of levels of oxidative stress and nitrosative stress in patients with epilepsy	12
Acute symptomatic seizures and COVID-19: Hospital-based study	12
Risk for respiratory and cardiovascular disease and mortality after non-trauma fracture and the mediating effects of respiratory and cardiovascular disease on mortality risk among adults with epilepsy	11
Development and validation of a clinical score to predict late seizures after intracerebral hemorrhage in Chinese	11
Anticonvulsant mechanisms of the ketogenic diet and caloric restriction	11
Dravet syndrome: A quick transition guide for the adult neurologist	11
Automated detection and segmentation of focal cortical dysplasias (FCDs) with artificial intelligence: Presentation of a novel convolutional neural network and its prospective clinical validation	11
Withanolide-A treatment exerts a neuroprotective effect via inhibiting neuroinflammation in the hippocampus after pilocarpine-induced status epilepticus	11
Changes of HMGB-1 and sTLR4 levels in cerebrospinal fluid of patients with febrile seizures	11

Cytokine-chemokine profiles in the hippocampus of patients with mesial temporal lobe epilepsy and hippocampal sclerosis	11
Prescription patterns of antiepileptic drugs for adult patients with newly diagnosed focal epilepsy from 2006 to 2017 in Japan	11
Relationship between hippocampal subfields and Verbal and Visual memory function in Mesial Temporal Lobe Epilepsy patients	11
Epidemiology of traumatic brain injury-associated epilepsy in western China: An analysis of multicenter data	11
18F-FDG PET/MR in focal epilepsy: A new step for improving the detection of epileptogenic lesions	11
Anti-seizure effects of walnut peptides in mouse models of induced seizure: The involvement of GABA and nitric oxide pathways	11
Neurocognitive Profiles of Pediatric Patients with ESES, Generalized Epilepsy, or Focal Epilepsy	11
Safety and efficacy of adjunctive lacosamide in Chinese and Japanese adults with epilepsy and focal seizures: A long-term, open-label extension of a randomized, controlled trial	11
A gut feeling about the ketogenic diet in epilepsy	11
Ciprofloxacin for treatment of drug-resistant epilepsy	11
Voxel-based morphometric MRI post-processing and PET/MRI co-registration reveal subtle abnormalities in cingulate epilepsy	11
Effect of lifetime antiepileptic drug treatment history on efficacy and tolerability of adjunctive brivaracetam in adults with focal seizures: Post-hoc analysis of a randomized, placebo-controlled tri	11
Neuroprotective effect of both synbiotics and ketogenic diet in a pentylenetetrazol-induced acute seizure murine model	11
Safety, tolerability, and efficacy of brivaracetam as adjunctive therapy in patients with focal seizures, generalized onset seizures, or Unverricht–Lundborg disease: An open-label, long-term follow-up	11
Perampanel effectiveness and safety as early add-on treatment for focal-onset seizures: PEREAGAL study	11
Functional connectivity disturbances of ascending reticular activating system and posterior thalamus in juvenile myoclonic epilepsy in relation with photosensitivity: A resting-state fMRI study	11
Epilepsy stigma in the Republic of Guinea and its socioeconomic and clinical associations: A cross-sectional analysis	10
Absence epilepsy in male and female WAG/Rij rats: A longitudinal EEG analysis of seizure expression	10
Brain-derived neurotrophic factor in patients with epilepsy: A systematic review and meta-analysis	10
Increased mortality after post-stroke epilepsy following primary intracerebral hemorrhage	10
Surgical candidates in children with epileptic spasms can be selected without invasive monitoring: A report of 70 cases	10
Interleukin-33 and oxidative stress in epilepsy patients	10
Not your parents’ ketogenic diet – Flexibility in 2020	10
Fenfluramine treatment for dravet syndrome: Real-world benefits on quality of life from the caregiver perspective	10
Quality of life and stigma in Lebanese people with epilepsy taking medication	10
Proteomic profiling of sclerotic hippocampus revealed dysregulated packaging of vesicular neurotransmitters in temporal lobe epilepsy	10
Inhibition of MEK-ERK signaling reduces seizures in two mouse models of tuberous sclerosis complex	10
Is vagal-nerve stimulation safe during pregnancy? A mini review	10
Long-term results of vagus nerve stimulation in children with Dravet syndrome: Time-dependent, delayed antiepileptic effect	10
Effects of SCN1A and SCN2A polymorphisms on responsiveness to valproic acid monotherapy in epileptic children	10
Automated video analysis of emotion and dystonia in epileptic seizures	9
Electroclinical pattern in the transition from West to Lennox-Gastaut syndrome	9
Performance analysis of EEG seizure detection features	9
Dual/double pathology in neurocysticercosis causing drug resistant epilepsy – Chance association or causal?	9
The effects of antiepileptic drugs on bone health: A systematic review	9
Comparison of long-term efficacy, tolerability, and safety of oxcarbazepine, lamotrigine, and levetiracetam in patients with newly diagnosed focal epilepsy: An observational study in the real world	9
Correlation of preoperative seizures with a wide range of tumor molecular markers in gliomas: An analysis of 442 glioma patients from China	9
Automated preprocessing and phase-amplitude coupling analysis of scalp EEG discriminates infantile spasms from controls during wakefulness	9
Cortical and subcortical volume differences between Benign Epilepsy with Centrotemporal Spikes and Childhood Absence Epilepsy	9
Kinetics of serum brain-derived neurotrophic factor (BDNF) concentration levels in epileptic patients after generalized tonic-clonic seizures	9
Factors associated with subjective cognitive function in epilepsy and psychogenic non-epileptic seizures	9
The anterior and centromedian thalamus: Anatomy, function, and dysfunction in epilepsy	9
DDESVSFS: A simple, rapid and comprehensive screening tool for the Differential Diagnosis of Epileptic Seizures VS Functional Seizures	9
Virtual epilepsy clinics – A Canadian Comprehensive Epilepsy Center experience pre-COVID and during the COVID-19 pandemic period	9
Prevalence study of epilepsy in Malaysia	9
Characterization and treatment of spontaneous recurrent seizures following nerve agent-induced status epilepticus in mice	8
Automated volumetry of hippocampal subfields in temporal lobe epilepsy	8
Complementary and alternative medicine (CAM) for epilepsy treatment in the Middle East and North Africa (MENA) region	8
Cardiac effects of rapid intravenous loading of lacosamide in patients with epilepsy	8
Aphasic status epilepticus in a tertiary referral center in Turkey: Clinical features, etiology, and outcome	8
Genomics in the presurgical epilepsy evaluation	8
Immediate versus late effects of vigabatrin on spike and wave discharges	8
Risk factors of paradoxical reactions to anti-seizure medication in genetic generalized epilepsy	8
Functional and structural connective disturbance of the primary and default network in patients with generalized tonic-clonic seizures	8
Artificial intelligence for medical image analysis in epilepsy	8
A systematic review and indirect treatment comparison of perampanel versus brivaracetam as adjunctive therapy in patients with focal-onset seizures with or without secondary generalization	8
Genetic diagnosis and clinical characteristics by etiological classification in early-onset epileptic encephalopathy with burst suppression pattern	8
White matter network disorder in mesial temporal epilepsy: An fMRI study	8
Precision treatment with nicotine in autosomal dominant sleep-related hypermotor epilepsy (ADSHE): An observational study of clinical outcome and serum cotinine levels in 17 patients	8
Beyond the Wada: An updated approach to pre-surgical language and memory testing	8
Brief history of electrical cortical stimulation: A journey in time from Volta to Penfield	8
Contribution of rare genetic variants to drug response in absence epilepsy	8
Effects of resective epilepsy surgery on the social determinants of health	7
Brain responsive neurostimulation device safety and effectiveness in patients with drug-resistant autoimmune-associated epilepsy	7
Racial and ethnic trends in antiseizure medications trial enrolment: A systematic review using ClinicalTrials.gov	7
The role of thalamic nuclei in genetic generalized epilepsies	7
Efficacy of perampanel in epilepsy patients with autism spectrum disorder	7
The single nucleotide variant n.60G>C in the microRNA-146a associated with susceptibility to drug-resistant epilepsy	7
Prevalence of comorbidities, and affective disorders in epilepsy: A latent class analysis approach	7
Risk of sudden unexpected death in people with epilepsy and obstructive sleep apnea	7
Immunotherapy for GRIN2A and GRIN2D-related epileptic encephalopathy	7
Surgical treatment in children with intractable epilepsy after viral encephalitis	7
Efficacy of cenobamate for uncontrolled focal seizures in patients with previous epilepsy-related surgery: Post hoc analysis of a phase 3, multicenter, open-label study	7
Characteristics of visual evoked potentials related to the electro-clinical expression of reflex seizures in photosensitive patients with idiopathic occipital lobe epilepsy	7
All that glitters: Contribution of stereo-EEG in patients with lesional epilepsy	7
Analysis of intraoperative human brain tissue transcriptome reveals putative risk genes and altered molecular pathways in glioma-related seizures	7
Epilepsy-associated increase in gonadotropin-releasing hormone neuron firing in diestrous female mice is independent of chronic seizure burden severity	7
Impact of carbamazepine on vitamin D levels: A meta-analysis	7
Quality of life and functional limitations in persons with epilepsy	7
Detection of preictal state in epileptic seizures using ensemble classifier	7

Telomere shortening in patients with drug-resistant epilepsy	7
Evaluation of lorcaserin as an anticonvulsant in juvenile Fmr1 knockout mice	7
A systematic review and meta-analysis of the association of ABCC2/ABCG2 polymorphisms with antiepileptic drug responses in epileptic patients	7
Apparent diffusion coefficient is associated with seizure outcome after magnetic resonance-guided laser interstitial thermal therapy for mesial temporal lobe epilepsy	7
Neuroimaging and thalamic connectomics in epilepsy neuromodulation	7
Evaluation of levocarnitine, lactulose, and combination therapy for the treatment of valproic acid-induced hyperammonemia in critically ill patients	7
The effects of Hippophae rhamnoides in neuroprotection and behavioral alterations against iron-induced epilepsy	7
The clinical significance of small sharp spikes: A retrospective study of 909 patients in epilepsy monitoring unit	7
Hypophosphatemia compared to classical biomarkers of tonic clonic seizures	7
The interactions between anticonvulsants and non-vitamin K antagonist oral anticoagulant agents: A systematic review	7
The value of magnetoencephalography for stereo-EEG-guided radiofrequency thermocoagulation in MRI-negative epilepsy	7
Role of pulse methylprednisolone in epileptic encephalopathy: A retrospective observational analysis	7
A SCN8A variant associated with severe early onset epilepsy and developmental delay: Loss- or gain-of-function?	7
Deep learning-based diagnosis of temporal lobe epilepsy associated with hippocampal sclerosis: An MRI study	7
Seizure outcomes in people with drug-resistant focal epilepsy evaluated for surgery but do not proceed	6
Phase 2, placebo-controlled clinical study of oral ganaxolone in PCDH19-clustering epilepsy	6
Essential oil related seizures (EORS): A multi-center prospective study on essential oils and seizures in adults	6
Efficacy and safety of eslicarbazepine acetate as a first or later adjunctive therapy in patients with focal seizures	6
Digoxin enhances the effect of antiepileptic drugs with different mechanism of action in the pentylenetetrazole-induced seizures in mice	6
Chronic intermittent hypoxia transiently increases hippocampal network activity in the gamma frequency band and 4-Aminopyridine-induced hyperexcitability in vitro	6
Network meta-analysis of antiepileptic drugs in focal drug-resistant epilepsy	6
Effect of automatic injectors on the injection latency, safety, and seizure onset zone localization of ictal single photon emission computed tomography studies in adult epilepsy monitoring unit	6
Is the antiseizure effect of ketogenic diet in children with drug-resistant epilepsy mediated through proinflammatory cytokines?	6
Quantitative proteomic analysis to identify differentially expressed proteins in patients with epilepsy	6
Pregnancy outcomes of refractory epilepsy patients treated with Brain–responsive neurostimulation	6
A Phase 3 open-label study of the efficacy, safety and pharmacokinetics of buccally administered midazolam hydrochloride for the treatment of status epilepticus in pediatric Japanese subjects	6
Comparison of subdural grid and stereoelectroencephalography in a cohort of pediatric patients	6
Spontaneous seizures in adult Fmr1 knockout mice: FVB.129P2-Pde6b+ Tyr Fmr1/J	6
Machine learning and statistic analysis to predict drug treatment outcome in pediatric epilepsy patients with tuberous sclerosis complex	6
Volumetric analysis of the piriform cortex in temporal lobe epilepsy	6
Investigation of dynamic functional connectivity of the source reconstructed epileptiform discharges in focal epilepsy: A graph theory approach	6
Flash-evoked high-frequency EEG oscillations in photosensitive epilepsies	6
Epilepsy with Eyelid myoclonias − A diagnosis concealed in other genetic generalized epilepsies with photoparoxysmal response	6
Knowledge of pregnancy and procreation in women with epilepsy of childbearing age: A 16-year comparative study in Poland	6
BCOR variants are associated with X-linked recessive partial epilepsy	6
Neural functional connectivity in patients with periventricular nodular heterotopia-mediated epilepsy	6
Feasibility of transcutaneous auricular vagus nerve stimulation in treatment of drug resistant epilepsy: A multicenter prospective study	6
The relation of major depression, OCD, personality disorders and affective temperaments with Temporal lobe epilepsy	6
Effects of antiseizure medications on placental cells: Focus on heterodimeric placental carriers	6
Proteomic profile differentiating between mesial temporal lobe epilepsy with and without hippocampal sclerosis	6
Challenges in epilepsy diagnosis and management in a low-resource setting: An experience from Bhutan	6
Recurrent seizures cause immature brain injury and changes in GABA a receptor α1 and γ2 subunits	6
Herb-drug interaction of gastrodiae rhizoma on carbamazepine: A pharmacokinetic study in rats	6
A framework for health equity in people living with epilepsy	6
CYP2C19 & UGT1A6 genetic polymorphisms and the impact on Valproic acid-induced weight gain in people with epilepsy: Prospective genetic association study	6
Changes in the use of antiseizure medications in children and adolescents in Norway, 2009–2018	6
Instruments for investigation of epilepsy in low- and middle-income countries: A systematic review	6
Effect of counselling of parents of children with epilepsy focusing on sudden unexpected death in epilepsy	6
Evaluation of the clinical characteristics of children with autism spectrum disorder and epilepsy and the perception of their parents on quality of life	6
Clinical and genetic characteristics of epilepsy of infancy with migrating focal seizures in Chinese children	6
Genome-wide microRNA profiling in brain and blood samples in a mouse model of epileptogenesis	6
Thalamic neuromodulation for epilepsy: A clinical perspective	6
Evaluation of psychiatric comorbidity in attention-deficit hyperactivity disorder with epilepsy: A case-control study	6
Comparison of physical fitness, activity, and quality of life of the children with epilepsy and their healthy peers	6
Effect of PIK3CA variants on glioma-related epilepsy and response to treatment	6
The clinical spectrum of familial and sporadic idiopathic generalized epilepsy	6
Single-subject gray matter networks in temporal lobe epilepsy patients with hippocampal sclerosis	6
Effects of a remotely delivered group-format epilepsy self-management program on adverse health outcomes in vulnerable people with epilepsy: A causal mediation analysis	6