Biochimica et Biophysica Acta-Molecular Basis of Disease

Papers
(The TQCC of Biochimica et Biophysica Acta-Molecular Basis of Disease is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)
ArticleCitations
Editorial Board156
Dietary fats modulate neuroinflammation in mucin 2 knock out mice model of spontaneous colitis150
TAX1BP1 downregulation by STAT3 in cardiac fibroblasts contributes to diabetes-induced heart failure with preserved ejection fraction141
Lack of Cyclin E1 in hepatocytes aggravates ethanol-induced liver injury and hepatic steatosis in experimental murine model of acute and chronic alcohol-associated liver disease108
Editorial Board92
Abnormal interaction of Rlip with mutant APP/Abeta and phosphorylated tau reduces wild-type Rlip levels and disrupt Rlip function in Alzheimer's disease92
Exploration of the role of mitochondria in reactive oxygen species generation under moderate hypoxia at the hippocampal CA3 area84
The effect of glutaminolysis inhibitors on in situ mitochondrial membrane potential81
Corrigendum to “CRISPR/Cas9 genome editing demonstrates functionality of the autoimmunity-associated SNP rs12946510” [Biochim. Biophys. Acta (BBA) - Mol. Basis Dis. 1869 (2023) 166599]76
CD8+ T cell metabolic changes in breast cancer70
FOXM1 promotes malignant biological behavior and metabolic reprogramming by targeting SPINK1 in hepatocellular carcinoma and affecting the p53 pathway69
IKZF1 promotes pyroptosis and prevents M2 macrophage polarization by inhibiting JAK2/STAT5 pathway in colon cancer67
Magnolol and Temozolomide exhibit a synergistic anti-glioma activity through MGMT inhibition66
ER stress modulated Klotho restoration: A prophylactic therapeutic strategy against acute kidney injury-diabetes comorbidity65
Study on the synthesis, characterization, and antitumor mechanism investigation of QZQ-01115 via targeting sphingosine kinase 254
Endotoxin-induced m6A RNA methylation landscape in lung endothelial cells: role of METTL3 in regulating inflammation and injury during acute lung injury51
Experimental and clinical perspectives on glycocalyx integrity and its relation to acute respiratory distress syndrome48
GEF-H1 drives breast cancer cells to tumor progression45
Sodium butyrate alleviates colitis by inhibiting mitochondrial ROS mediated macrophage pyroptosis44
Corrigendum to “Small extracellular vesicles-mediated cellular interactions between tumor cells and tumor-associated macrophages: Implication for immunotherapy” [Biochim. Biophys. Acta (BBA) – Mol. Ba42
IFN-γ-responsiveness of lymphatic endothelial cells inhibits melanoma lymphatic dissemination via AMPK-mediated metabolic control40
Role of elastic fiber degradation in disease pathogenesis40
Necroptosis signaling and NLRP3 inflammasome cross-talking in epithelium facilitate Pseudomonas aeruginosa mediated lung injury38
FGF21 at physiological concentrations regulates vascular endothelial cell function through multiple pathways38
The role of heart and neural crest derivatives-expressed protein factors in pregnancy37
Enhanced glycolysis by ATPIF1 gene inactivation increased the anti-bacterial activities of neutrophils through induction of ROS and lactic acid36
Recognition of asymptomatic hypercholanemia of pregnancy: Different clinical features, fetal outcomes and bile acids metabolism from intrahepatic cholestasis of pregnancy36
Characterization of prokineticin system in Crohn's disease pathophysiology and pain, and its modulation by alcohol abuse: A preclinical study35
miR-653-3p promotes genomic instability of colorectal cancer cells via targeting SIRT1/TWIST1 signaling pathway34
Reduced parenteral glucose supply during neonatal infection attenuates neurological and renal pathology associated with modulation of innate and Th1 immunity34
Targeting the reprogrammed metabolism in H3.3K27M pediatric high-grade gliomas34
Epigenetic regulation of autophagy in gastrointestinal cancers33
Exploring ocular fibulin-3 (EFEMP1): Anatomical, age-related, and species perspectives33
The striking differences in the bioenergetics of brain and liver mitochondria are enhanced in mitochondrial disease33
Pregnancy and pandemics: Interaction of viral surface proteins and placenta cells33
GLUT1 mediates the release of HMGB1 from airway epithelial cells in mixed granulocytic asthma32
Potential protective role of let-7d-5p in atherosclerosis progression reducing the inflammatory pathway regulated by NF-κB and vascular smooth muscle cells proliferation32
The paradox of fatty-acid β-oxidation in muscle insulin resistance: Metabolic control and muscle heterogeneity32
RGS1 can serve as a long-term prognostic marker in gastric cancer by promoting the infiltration and polarization of macrophages31
Gut-based manipulations spur hippocampal mitochondrial bioenergetics in a model of pediatric epilepsy31
Functional characterisation of the ACE2 orthologues in Drosophila provides insights into the neuromuscular complications of COVID-1931
Pharmacological inhibition of CFTR attenuates nonalcoholic steatohepatitis (NASH) progression in mice31
Splice variants of metabolic nuclear receptors: Relevance for metabolic disease and therapeutic targeting30
Pentacyclic triterpene oleanolic acid protects against cardiac aging through regulation of mitophagy and mitochondrial integrity30
Senkyunolide I ameliorates thoracic aortic aneurysm and dissection in mice via inhibiting the oxidative stress and apoptosis of endothelial cells29
tp53 R217H and R242H mutant zebrafish exhibit dysfunctional p53 hallmarks and recapitulate Li-Fraumeni syndrome phenotypes29
Fibroblast-specific MyD88-dependent signaling aggravates inflammation and cardiac dysfunction in the MI heart29
Endocytic trafficking of connexins in cancer pathogenesis29
Loss of YB-1 alleviates liver fibrosis by suppressing epithelial-mesenchymal transition in hepatic progenitor cells28
RhFGF21 protects the skin from UVB irradiation in diabetic mice through the inhibition of epidermal cell apoptosis and macrophage-mediated inflammation via the SIRT1 signaling pathway28
VRK2 promotes colorectal cancer growth and impedes immunotherapy and 5-FU treatment efficacy28
Corrigendum to “Polycystin-1 downregulation induces ERK-dependent mTOR pathway activation in a cellular model of psoriasis” [BBA – Mol. Basis Dis. 1864 (2018) 3468–3476]27
Integrated application of transcriptome and metabolomics reveals potential therapeutic targets for the polarization of atherosclerotic macrophages26
Elevated senescence in the bone marrow mesenchymal stem cells of acquired aplastic anemia patients: A possible implication of DNA damage responses and telomere attrition26
Proximal tubular Bmal1 protects against chronic kidney injury and renal fibrosis by maintaining of cellular metabolic homeostasis26
CRISPR-Cas9 mediated knockout of NDUFS4 in human iPSCs: A model for mitochondrial complex I deficiency25
Loss of USP22 alleviates cardiac hypertrophy induced by pressure overload through HiF1-α-TAK1 signaling pathway25
Lithocholic acid promotes rosacea-like skin inflammation via G protein-coupled bile acid receptor 125
Endothelial cell-derived pro-fibrotic factors increase TGF-β1 expression by smooth muscle cells in response to cycles of hypoxia-hyperoxia25
Integration of proteomic and metabolomic analysis reveal distinct metabolic alterations of prostate cancer-associated fibroblasts compared to normal fibroblasts from patient's stroma samples24
ETS1 and RBPJ transcriptionally regulate METTL14 to suppress TGF-β1-induced epithelial-mesenchymal transition in human bronchial epithelial cells24
Upregulation of GRP78 is accompanied by decreased antioxidant response and mitophagy promotion in streptozotocin-induced type 1 diabetes in rats24
Microglial pyroptosis drives neuropathic pain and targeting NLRP3 alleviates pain and neuroinflammation24
Corrigendum to paper entitled “Seronegative patients with primary Sjogren's syndrome and non-pSS sicca test positive for anti-SSA/Ro52 and -Ro60 in saliva” [Published in: BBA – Mol. Basis Dis. Volume 23
Oleanonic acid ameliorates mutant Aβ precursor protein-induced oxidative stress, autophagy deficits, ferroptosis, mitochondrial damage, and ER stress in vitro23
Editorial Board23
Carbon monoxide and mitochondria: Cell energy and fate control23
Cytotoxic profile of naturally occurring abietane diterpenoids in urothelial carcinoma cells23
Sex-Specific Impact of Maternal Obesity and Gestational Exercise on Offspring's Cardiac Health: Insights into Mitochondrial Function and NO Signaling23
Miro1 role in intra- and inter-cellular mitochondrial movement in tumour microenvironment23
Impaired mitochondrial metabolism and ER-mitochondria contact sites affect signaling in cancer cells23
Association of proteomics with lymph node metastasis in early gastric cancer patients22
Amylin is incorporated into extracellular vesicles in an ESCRT-dependent manner and regulates senescence22
Remodeling of lipid landscape in high fat fed very-long chain acyl-CoA dehydrogenase null mice favors pro-arrhythmic polyunsaturated fatty acids and their downstream metabolites22
Severe neonatal MEGDHEL syndrome with a homozygous truncating mutation in SERAC122
Biological evaluation of novel dually-targeted metalloconjugates containing a PSMA inhibitor and a TPP group for prostate cancer theranostics22
Programmed cell death protein 5 inhibits hepatocellular carcinoma progression by inducing pyroptosis through regulation of TGF-β/Smad2/3/Snail pathway21
A disturbed metabolite-GPCR axis is associated with microbial dysbiosis in IBD patients: Potential role of GPR109A in macrophages21
Identification of m6A-related biomarkers in Kawasaki disease21
The curious case of mitochondrial sirtuin in rewiring breast cancer metabolism: Mr Hyde or Dr Jekyll?21
Plasma exosomes in obesity hypoventilation syndrome patients drive lung cancer cell malignant properties: Effect of long-term adherent CPAP treatment21
Unravelling the impact of QRICH1 modulation on endoplasmic reticulum stress and neuronal apoptosis in traumatic brain injury21
Reactive oxygen species in colorectal cancer adjuvant therapies21
Inflammatory and tolerogenic dendritic cells and T lymphocytes in Graves' thyroidal and orbital disease21
Microglia toxicology in α-synuclein pathology20
Serinc2 antagonizes pressure overload-induced cardiac hypertrophy via regulating the amino acid/mTORC1 signaling pathway20
A novel causative role of imbalanced kynurenine pathway in ulcerative colitis: Upregulation of KMO and KYNU promotes intestinal inflammation20
Integrated multiomic analysis identifies TRIP13 as a mediator of alveolar epithelial type II cell dysfunction in idiopathic pulmonary fibrosis20
NAT2 activity increases cytotoxicity of anthracycline antibiotics and HDAC inhibitors20
Interactions between daily sleep-wake rhythms, γ-secretase, and amyloid-β peptide pathology point to complex underlying relationships20
Nicotinamide riboside kinase 2: A unique target for skeletal muscle and cardiometabolic diseases20
Mitochondria and Hypoxia Signalling20
Special issue - Mitochondria in aging, cancer and cell death20
Cholesterol redistribution triggered by CYP46A1 gene therapy improves major hallmarks of Niemann-Pick type C disease but is not sufficient to halt neurodegeneration20
FOXQ1, deubiquitinated by USP10, alleviates sepsis-induced acute kidney injury by targeting the CREB5/NF-κB signaling axis20
The role of mito-ribosomal fidelity in human disease: structural analysis of deafness-related mtDNA variants mapping to mitochondrial rRNA genes19
Combined cryoablation and PD-1 inhibitor synergistically enhance antitumor immune responses in Lewis lung adenocarcinoma mice via the PI3K/AKT/mTOR pathway19
Proteomic- and metabolomic-based mechanisms of androgen-mediated right ventricular maladaptive remodeling under pressure overload19
Editorial Board19
Mitochondrial turnover in neurodegeneration and ageing19
Micro-RNAs targeting the estrogen receptor alpha involved in endocrine therapy resistance in breast cancer19
Follicular CD8+ T cells promote immunoglobulin production and demyelination in multiple sclerosis and a murine model19
AOX delays the onset of the lethal phenotype in a mouse model of Uqcrh (complex III) disease18
An unusual signal transducer GIV/Girdin engages in the roles of adipocyte-derived hormone leptin in liver fibrosis18
Intestinal microbiota-derived membrane vesicles and their role in chronic kidney disease18
Lamprey immunity protein enables early detection and recurrence monitoring for bladder cancer through recognizing Neu5Gc-modified uromodulin glycoprotein in urine18
Editorial Board18
WWOX: a promoter of brain mitochondrial dysfunction in a mouse model of type 2 diabetes18
The ovine Type II Gaucher disease model recapitulates aspects of human brain disease.18
A spectrum of AKT3 activating mutations cause focal malformations of cortical development (FMCDs) in cortical organoids18
Over-activated hemichannels: A possible therapeutic target for human diseases18
Platelets promote metastasis of intrahepatic cholangiocarcinoma through activation of TGF-β/Smad2 pathway18
Adipocyte coculture induces a pro-inflammatory, fibrotic, angiogenic, and proliferative microenvironment in uterine leiomyoma cells17
Icariin attenuates excessive alcohol consumption-induced susceptibility to atrial fibrillation through SIRT3 signaling17
Physical interaction between STAT3 and AP1 in cervical carcinogenesis: Implications in HPV transcription control17
Dehydrozingerone ameliorates renal structure compromised in diabetic nephropathy17
Upregulation of inflammatory genes and pathways links obesity to severe COVID-1917
Light deficiency in Apoe−/−mice increases atheroma plaque size and vulnerability by modulating local immunity17
Aerobic exercise ameliorates insulin resistance in C57BL/6 J mice via activating Sestrin317
Neuroinflammation in fetal alcohol spectrum disorders and related novel therapeutic approaches17
The IP3R inhibitor desmethylxestospongin B reduces tumor cell migration, invasion and metastasis by impairing lysosome acidification and β1-integrin recycling17
The contribution and therapeutic implications of IGHMBP2 mutations on IGHMBP2 biochemical activity and ABT1 association17
PADI4 negatively regulates RIG-I-mediated antiviral response through deacetylation of IFN-β promoter via HDAC117
Adenine nucleotide translocase 2 silencing promotes metabolic reprogramming in P19 embryonal carcinoma stem cells17
Role of acute exposure to environmental stressors in the gut-brain-periphery axis in the presence of cognitive resilience17
Hypoxic stress promotes astrocyte infiltration-like growth via HIF-1α/GDNF/LOXL2 axis16
Immunometabolism and the modulation of immune responses and host defense: A role for methylglyoxal?16
Targeted inhibition of branched-chain amino acid metabolism drives apoptosis of glioblastoma by facilitating ubiquitin degradation of Mfn2 and oxidative stress16
Trained immunity in viral infections, Alzheimer's disease and multiple sclerosis: A convergence in type I interferon signalling and IFNβ-1a16
Phytochemical strategies in glioblastoma therapy: Mechanisms, efficacy, and future perspectives16
Caspase-3 and gasdermin E detection in peri-implantitis16
The role of autophagy in the metabolism and differentiation of stem cells16
Exploring the role and application of mitochondria in radiation therapy16
Suppression of PCK1 attenuates neuronal injury and improves post-resuscitation outcomes16
Discovery of 2,8-dihydroxyadenine in HUA patients with uroliths and biomarkers for its associated nephropathy16
Unraveling the pathogenesis of viral-induced pulmonary arterial hypertension: Possible new therapeutic avenues with mesenchymal stromal cells and their derivatives.15
Aptamers against cancer drug resistance: Small fighters switching tactics in the face of defeat15
Pannexin-2 deficiency disrupts visual pathways and leads to ocular defects in zebrafish15
An in-depth review of AI-powered advancements in cancer drug discovery15
Dysfunction of CCT3-associated network signals for the critical state during progression of hepatocellular carcinoma15
Oxygen-sensitive Regulation of Mitochondrial Mass and its implication in the von Hippel-Lindau Syndrome15
Growth impairment, increased placental glucose uptake and altered transplacental transport in VIP deficient pregnancies: Maternal vs. placental contributions15
The E2 ubiquitin-conjugating enzyme HIP2 is a crucial regulator of quality control against mutant SOD1 proteotoxicity15
A dual sensing mechanism of eastern honeybee Apis cerana that upregulates the expression level of chemosensory protein CSP1 and enhances the binding affinity to loquat floral volatiles at low temperat15
Integrated analysis of single-cell RNA-seq and bulk RNA-seq to unravel the molecular mechanisms underlying the immune microenvironment in the development of intestinal-type gastric cancer15
Immune infiltration related CENPI associates with the malignant features and drug resistance of lung adenocarcinoma15
HIV and gp120-induced lipid droplets loss in hepatic stellate cells contribute to profibrotic profile15
Identification of m6A modification patterns and RBM15 mediated macrophage phagocytosis in pancreatic cancer: An integrative analysis15
Sfrp2 promotes renal dysfunction of diabetic kidney disease via modulating Fzd5-induced cytosolic calcium ion concentration and CaMKII/Mek/Erk pathway in mesangial cells15
Metabolic adaptations in cancer stem cells: A key to therapy resistance15
Therapeutic potential of AAV-FL-Klotho in obesity: Impact on weight loss and lipid metabolism in mice15
Prevotella copri ameliorates cholestasis and liver fibrosis in primary sclerosing cholangitis by enhancing the FXR signalling pathway15
Modern insights of nanotheranostics in the glioblastoma: An updated review15
Ncl liquid-liquid phase separation and SUMOylation mediate the stabilization of HIF-1α expression and promote pyroptosis in ischemic hindlimb15
Mechanism of multifunctional adaptor protein SHARPIN regulating myocardial fibrosis and how SNP mutation affect the prognosis of myocardial infarction14
Dihydroceramide desaturase modulates autolysosome maturation and ameliorates CRB1 retinopathy14
Extracellular RNAs/TLR3 signaling contributes to acute intestinal injury induced by intestinal ischemia reperfusion in mice14
TNF-α drives bladder cancer metastasis via METTL3-mediated m6A modification to promote CLASP2/IQGAP1-dependent cytoskeleton remodeling14
Suppression of intestinal Ticam1 ameliorated MASH via Akkermansia muciniphila QAA37749.1 mediated betaine transformation14
Loss of cytidine deaminase expression as a potential attempt to counteract the process of carcinogenesis by reducing basal PARP-1 activity and increasing tau levels14
Sex differences feed into nuclear receptor signaling along the digestive tract14
Autophagy unveiled: New horizons in health and disease14
IGF1R-α6 integrin-S100A4 network governs the organ-specific metastasis of chemoresistant epithelial ovarian cancer cells14
Editorial to special issue of BBADIS: Brain-gut interaction and cognitive control14
IL-10 alleviates aTCMR by inhibiting NFATc1 signaling pathway of T cells after kidney transplantation14
GPR68 supports AML cells through the calcium/calcineurin pro-survival pathway and confers chemoresistance by mediating glucose metabolic symbiosis14
Electroacupuncture pre-treatment exerts a protective effect on LPS-induced cardiomyopathy in mice through the delivery of miR-381 via exosomes14
Therapeutic targeting of HYPDH/PRODH2 with N-propargylglycine offers a Hyperoxaluria treatment opportunity14
Impaired IL-27 signaling aggravates macrophage senescence and sensitizes premature ovarian insufficiency induction by high-fat diet14
Mitochondrial classic metabolism and its often-underappreciated facets14
RASEF/Rab45 regulates the formation and sorting of zymogen granules and secretion of digestive enzymes by pancreatic acinar cells14
A prospective diagnostic and prognostic biomarker for hepatocellular carcinoma that functions in glucose metabolism regulation: Solute carrier family 37 member 314
The (un)known crosstalk between metabolism and mechanotransduction: Implications for metabolic syndrome (MetS)-associated neurological complications14
BCAR1 facilitates the survival of lung adenocarcinoma cells by augmenting the unfolded protein response, autophagy, and the formation of vasculogenic mimicry14
Absence of MMACHC in peripheral retinal cells does not lead to an ocular phenotype in mice14
Kinase library screening identifies IGF-1R as an oncogenic vulnerability in intrahepatic cholangiocarcinoma stem-like cells13
Dapagliflozin attenuates AKI to CKD transition in diabetes by activating SIRT3/PGC1-α signaling and alleviating aberrant metabolic reprogramming13
GBP1 promotes acute rejection after liver transplantation by inducing Kupffer cells pyroptosis13
Toxoplasma gondii autophagy-related protein ATG7 maintains apicoplast inheritance by stabilizing and lipidating ATG813
Downregulation of PGC-1α during cisplatin-induced muscle atrophy in murine skeletal muscle13
Copper induces liver lipotoxicity disease by up-regulating Nrf2 expression via the activation of MTF-1 and inhibition of SP1/Fyn pathway13
CTGF regulated by ATF6 inhibits vascular endothelial inflammation and reduces hepatic ischemia–reperfusion injury13
Epigenetics in autosomal dominant polycystic kidney disease13
CXCL12 derived from CD248-expressing cancer-associated fibroblasts mediates M2-polarized macrophages to promote nonsmall cell lung cancer progression13
Exosomes derived from periodontitis induce hepatic steatosis through the SCD-1/AMPK signaling pathway13
A novel function of claudin-5 in maintaining the structural integrity of the heart and its implications in cardiac pathology13
Metformin exposure during pregnancy and lactation affects offspring's long-term body weight and adipose tissue mass independent of the maternal metabolic state13
Myo6 mediates osteoclast function and is essential for joint damage in collagen-induced arthritis13
Hyperglycemia and circadian disruption lead to retinal dysfunction in a stabilized colony of the fat sand rat Psammomys obesus13
SIRT6 controls hepatic lipogenesis by suppressing LXR, ChREBP, and SREBP113
Procollagen-lysine 2-oxoglutarate 5-dioxygenase 2 promotes collagen cross-linking and ECM stiffening to induce liver fibrosis13
The evil relationship between liver fibrosis and cardiovascular disease in metabolic dysfunction-associated fatty liver disease (MAFLD): Looking for the culprit13
Correlated with better prognosis, CSTA inhibits metastasis of nasopharyngeal carcinoma cells via suppressing AKT signaling through promoting METTL3 degradation13
The microenvironment of secondary lymphedema. The key to finding effective treatments?13
The spike protein of SARS-CoV-2 induces heme oxygenase-1: Pathophysiologic implications13
Increased NPM1 inhibit ferroptosis and aggravate renal fibrosis via Nrf2 pathway in chronic kidney disease13
Metformin alleviates liver fibrosis in mice by enriching Lactobacillus sp. MF-1 in the gut microbiota13
Therapeutic benefits of central LH receptor agonism in the APP/PS1 AD model involve trophic and immune regulation and are reproductive status dependent12
Rapid diagnosis of malignant pleural mesothelioma and its discrimination from lung cancer and benign exudative effusions using blood serum12
Gamut of glycolytic enzymes in vascular smooth muscle cell proliferation: Implications for vascular proliferative diseases12
Uterine leiomyoma as useful model to unveil morphometric and macromolecular collagen state and impairment in fibrotic diseases: An ex-vivo human study12
WTAP promotes macrophage recruitment and increases VEGF secretion via N6-methyladenosine modification in corneal neovascularization12
A genome wide screening to identify mediators of cellular senescence induced by loss of the mitochondrial fission protein Fis112
Editorial Board12
Apigenin enhancing oxidative resistance and proteostasis to extend lifespan via PTEN-mediated AKT signalling pathway12
Meteorin-like (METRNL) attenuates hypertensive induced cardiac hypertrophy by inhibiting autophagy via activating BRCA212
P75NTR regulates autophagy through the YAP-mTOR pathway to increase the proliferation of interfollicular epidermal cells and promote wound healing in diabetic mice12
An emerging role of the 5′ termini of mature tRNAs in human diseases: Current situation and prospects12
Differential accumulation of human β-amyloid and tau from enriched extracts in neuronal and endothelial cells12
Local modulation of thyroid hormone signaling in the retina affects the development of diabetic retinopathy12
The Cellular Response to Hypoxia Depends on the Baseline Conditions: Normoxia versus Physioxia12
Confrontation with kidney inflammation through a HMGB1-targeted peptide augments anti-fibrosis therapy12
Identification of remodeled collagen fibers in tumor stroma by FTIR Micro-spectroscopy: A new approach to recognize the colon carcinoma12
Depletion of Mcpip1 in murine myeloid cells results in intestinal dysbiosis followed by allergic inflammation12
CD36-mediated accumulation of MDSCs exerts abscopal immunosuppressive responses in hepatocellular carcinoma after insufficient microwave ablation12
Clotrimazole presents anticancer properties against a mouse melanoma model acting as a PI3K inhibitor and inducing repolarization of tumor-associated macrophages12
The Annexin A2-Notch regulatory loop in hepatocytes promotes liver fibrosis in NAFLD by increasing osteopontin expression12
Resistance exercise preconditioning prevents disuse muscle atrophy by inhibiting apoptosis and protein degradation via SESN2 in C57BL/6J mice12
The mitochondrial signature of cultured endothelial cells in sepsis: Identifying potential targets for treatment12
Blood-based DNA methylation signatures in cancer: A systematic review12
The protective effect of forsythiaside A on 3,5-diethoxycarbonyl-1,4-dihydrocollidine-induced cholestatic liver injury in mice: Based on targeted metabolomics and molecular biology technology12
The in situ transcriptomic landscape of breast tumour-associated and normal adjacent endothelial cells12
Melatonin and metformin ameliorated trastuzumab-induced cardiotoxicity through the modulation of mitochondrial function and dynamics without reducing its anticancer efficacy12
How does the natural compound 7α-acetoxy-6β-hydroxyroyleanone (Roy) modulates glioblastoma cells autophagy?12
Inhibition of Mettl3 ameliorates osteoblastic senescence by mitigating m6A modifications on Slc1a5 via Igf2bp2-dependent mechanisms12
Hypoxia induced deregulation of sphingolipids in colon cancer is a prognostic marker for patient outcome11
NPC1-like phenotype, with intracellular cholesterol accumulation and altered mTORC1 signaling in models of Parkinson's disease11
Patient-Derived Organoids Allow for Studying Resistance of Malignant Mesothelioma to Therapy11
Cisplatin reduces immunosuppression caused by tumor-associated macrophages through downregulating CD47-SIRPα signaling in glioblastoma11
Dysregulated autophagy: A key player in the pathophysiology of type 2 diabetes and its complications11
Single-nucleus transcriptome profiling provides insights into the pathophysiology of adhesive arachnoiditis11
Estrogen receptor β attenuates renal fibrosis by suppressing the transcriptional activity of Smad311
Phosphorylated TAR DNA-binding protein-43: Aggregation and antibody-based inhibition11
Zika virus infection impairs synaptogenesis, induces neuroinflammation, and could be an environmental risk factor for autism spectrum disorder outcome11
Nuclear factor of activated T-cells (NFAT) regulation of IL-1β-induced retinal vascular inflammation11
BAP18 acting as a novel peroxisome proliferator-activated receptor α co-regulator contributes to hepatocellular carcinoma progression11
CD36 inhibition corrects lipid-FetuinA mediated insulin secretory defects by preventing intracellular lipid accumulation and inflammation in the pancreatic beta cells11
Zika virus infection triggers the melanization response in Drosophila11
A novel mTORC2-Akt-ROS axis triggers mitophagy and mitofission associated execution of mutant KRAS expressing cancers11
Sports training improves motor function after spinal cord injury by regulating microtubule dynamics11
Apolipoprotein E ε4 triggers neurotoxicity via cholesterol accumulation, acetylcholine dyshomeostasis, and PKCε mislocalization in cholinergic neuronal cells11
Deubiquitylase PSMD14 inhibits autophagy to promote ovarian cancer progression via stabilization of LRPPRC11
Electroacupuncture pretreatment maintains mitochondrial quality control via HO-1/MIC60 signaling pathway to alleviate endotoxin-induced acute lung injury11
Orexin-A/OX1R is involved in regulation of autophagy to promote cortisol secretion in adrenocortical cell11
Corrigendum to “Pregnane X receptor (PXR) protects against cisplatin-induced acute kidney injury in mice” [Biochim. Biophys. Acta, Mol. Basis Dis. 1867(3) 2021 Mar 1, 165996./BBADIS-20-505]11
Nutrigenomics of inward rectifier potassium channels11
Evolving perspectives regarding the role of the PD-1/PD-L1 pathway in gastric cancer immunotherapy11
Conditional Pten inactivation in pituitary results in sex-specific prolactinoma formation11
PGC-1α role in rescuing ferroptosis in cerebral ischemia/reperfusion injury through promoting mitochondrial biogenesis and UCP2 expression11
Protein kinase D: A therapeutic target in experimental alcoholic pancreatitis11
0.38774704933167