Biochimica et Biophysica Acta-Molecular Basis of Disease

Article	Citations
Editorial Board	156
Indole-3 propionate inhibits NF-κB/NLRP3-mediated osteoclastogenesis and improves bone quality in high-fat-diet induced obese mice	146
STRA13 exacerbates T2DM-induced diabetic cardiomyopathy by regulating the RXRα/UCP-1 signaling pathway	117
FBXW8-mediated degradation of PPT1 suppresses epithelial-mesenchymal transition and metastasis in hepatocellular carcinoma	97
Experimental and clinical perspectives on glycocalyx integrity and its relation to acute respiratory distress syndrome	93
Exploration of the role of mitochondria in reactive oxygen species generation under moderate hypoxia at the hippocampal CA3 area	85
STEAP3 alleviates inflammation and fibrosis via iron metabolism in ischemia/reperfusion-associated lung injury	85
The effect of glutaminolysis inhibitors on in situ mitochondrial membrane potential	82
Editorial Board	80
Abnormal interaction of Rlip with mutant APP/Abeta and phosphorylated tau reduces wild-type Rlip levels and disrupt Rlip function in Alzheimer's disease	74
TAX1BP1 downregulation by STAT3 in cardiac fibroblasts contributes to diabetes-induced heart failure with preserved ejection fraction	72
Magnolol and Temozolomide exhibit a synergistic anti-glioma activity through MGMT inhibition	66
Study on the synthesis, characterization, and antitumor mechanism investigation of QZQ-01115 via targeting sphingosine kinase 2	58
Endotoxin-induced m6A RNA methylation landscape in lung endothelial cells: role of METTL3 in regulating inflammation and injury during acute lung injury	56
ER stress modulated Klotho restoration: A prophylactic therapeutic strategy against acute kidney injury-diabetes comorbidity	54
IKZF1 promotes pyroptosis and prevents M2 macrophage polarization by inhibiting JAK2/STAT5 pathway in colon cancer	48
The paradox of fatty-acid β-oxidation in muscle insulin resistance: Metabolic control and muscle heterogeneity	46
Functional characterisation of the ACE2 orthologues in Drosophila provides insights into the neuromuscular complications of COVID-19	46
tp53 R217H and R242H mutant zebrafish exhibit dysfunctional p53 hallmarks and recapitulate Li-Fraumeni syndrome phenotypes	43
Reduced parenteral glucose supply during neonatal infection attenuates neurological and renal pathology associated with modulation of innate and Th1 immunity	42
Characterization of prokineticin system in Crohn's disease pathophysiology and pain, and its modulation by alcohol abuse: A preclinical study	41
Potential protective role of let-7d-5p in atherosclerosis progression reducing the inflammatory pathway regulated by NF-κB and vascular smooth muscle cells proliferation	41
IFN-γ-responsiveness of lymphatic endothelial cells inhibits melanoma lymphatic dissemination via AMPK-mediated metabolic control	40
Corrigendum to “CRISPR/Cas9 genome editing demonstrates functionality of the autoimmunity-associated SNP rs12946510” [Biochim. Biophys. Acta (BBA) - Mol. Basis Dis. 1869 (2023) 166599]	39
Pharmacological inhibition of CFTR attenuates nonalcoholic steatohepatitis (NASH) progression in mice	39

FGF21 at physiological concentrations regulates vascular endothelial cell function through multiple pathways	38
Lack of Cyclin E1 in hepatocytes aggravates ethanol-induced liver injury and hepatic steatosis in experimental murine model of acute and chronic alcohol-associated liver disease	37
Enhanced glycolysis by ATPIF1 gene inactivation increased the anti-bacterial activities of neutrophils through induction of ROS and lactic acid	37
Role of elastic fiber degradation in disease pathogenesis	36
Senkyunolide I ameliorates thoracic aortic aneurysm and dissection in mice via inhibiting the oxidative stress and apoptosis of endothelial cells	36
The striking differences in the bioenergetics of brain and liver mitochondria are enhanced in mitochondrial disease	36
miR-653-3p promotes genomic instability of colorectal cancer cells via targeting SIRT1/TWIST1 signaling pathway	35
Pentacyclic triterpene oleanolic acid protects against cardiac aging through regulation of mitophagy and mitochondrial integrity	35
Recognition of asymptomatic hypercholanemia of pregnancy: Different clinical features, fetal outcomes and bile acids metabolism from intrahepatic cholestasis of pregnancy	34
Targeting the reprogrammed metabolism in H3.3K27M pediatric high-grade gliomas	34
Exploring ocular fibulin-3 (EFEMP1): Anatomical, age-related, and species perspectives	34
Corrigendum to “Small extracellular vesicles-mediated cellular interactions between tumor cells and tumor-associated macrophages: Implication for immunotherapy” [Biochim. Biophys. Acta (BBA) – Mol. Ba	33
Epigenetic regulation of autophagy in gastrointestinal cancers	33
GEF-H1 drives breast cancer cells to tumor progression	32
Dietary fats modulate neuroinflammation in mucin 2 knock out mice model of spontaneous colitis	32
Endocytic trafficking of connexins in cancer pathogenesis	32
The role of heart and neural crest derivatives-expressed protein factors in pregnancy	32
Pregnancy and pandemics: Interaction of viral surface proteins and placenta cells	30
Fibroblast-specific MyD88-dependent signaling aggravates inflammation and cardiac dysfunction in the MI heart	30
FOXM1 promotes malignant biological behavior and metabolic reprogramming by targeting SPINK1 in hepatocellular carcinoma and affecting the p53 pathway	30
CD8+ T cell metabolic changes in breast cancer	30
GLUT1 mediates the release of HMGB1 from airway epithelial cells in mixed granulocytic asthma	30
Necroptosis signaling and NLRP3 inflammasome cross-talking in epithelium facilitate Pseudomonas aeruginosa mediated lung injury	30
RGS1 can serve as a long-term prognostic marker in gastric cancer by promoting the infiltration and polarization of macrophages	28
Sodium butyrate alleviates colitis by inhibiting mitochondrial ROS mediated macrophage pyroptosis	28
Gut-based manipulations spur hippocampal mitochondrial bioenergetics in a model of pediatric epilepsy	28
Hippocampal proteomic signatures of the ketogenic diet in a model of infantile epileptic spasms syndrome	28
NAT2 activity increases cytotoxicity of anthracycline antibiotics and HDAC inhibitors	27
RhFGF21 protects the skin from UVB irradiation in diabetic mice through the inhibition of epidermal cell apoptosis and macrophage-mediated inflammation via the SIRT1 signaling pathway	27
Microglia toxicology in α-synuclein pathology	26
Serinc2 antagonizes pressure overload-induced cardiac hypertrophy via regulating the amino acid/mTORC1 signaling pathway	26
Loss of USP22 alleviates cardiac hypertrophy induced by pressure overload through HiF1-α-TAK1 signaling pathway	26
Integrated multiomic analysis identifies TRIP13 as a mediator of alveolar epithelial type II cell dysfunction in idiopathic pulmonary fibrosis	26
Miro1 role in intra- and inter-cellular mitochondrial movement in tumour microenvironment	25
Corrigendum to “Polycystin-1 downregulation induces ERK-dependent mTOR pathway activation in a cellular model of psoriasis” [BBA – Mol. Basis Dis. 1864 (2018) 3468–3476]	25
A novel causative role of imbalanced kynurenine pathway in ulcerative colitis: Upregulation of KMO and KYNU promotes intestinal inflammation	25
Cytotoxic profile of naturally occurring abietane diterpenoids in urothelial carcinoma cells	24
Editorial Board	24
Programmed cell death protein 5 inhibits hepatocellular carcinoma progression by inducing pyroptosis through regulation of TGF-β/Smad2/3/Snail pathway	24
Impaired mitochondrial metabolism and ER-mitochondria contact sites affect signaling in cancer cells	24
Sex-Specific Impact of Maternal Obesity and Gestational Exercise on Offspring's Cardiac Health: Insights into Mitochondrial Function and NO Signaling	24
Normal urinary oxalate excretion in 4-hydroxy-2-oxo-glutarate aldolase 1 (HOGA1) deficient mice with AGT expression in peroxisomes and not in mitochondria	24
Corrigendum to paper entitled “Seronegative patients with primary Sjogren's syndrome and non-pSS sicca test positive for anti-SSA/Ro52 and -Ro60 in saliva” [Published in: BBA – Mol. Basis Dis. Volume	24
Cholesterol redistribution triggered by CYP46A1 gene therapy improves major hallmarks of Niemann-Pick type C disease but is not sufficient to halt neurodegeneration	24
Unravelling the impact of QRICH1 modulation on endoplasmic reticulum stress and neuronal apoptosis in traumatic brain injury	24
Identification of m6A-related biomarkers in Kawasaki disease	23
Reactive oxygen species in colorectal cancer adjuvant therapies	23
ETS1 and RBPJ transcriptionally regulate METTL14 to suppress TGF-β1-induced epithelial-mesenchymal transition in human bronchial epithelial cells	22
Association of proteomics with lymph node metastasis in early gastric cancer patients	22
FOXQ1, deubiquitinated by USP10, alleviates sepsis-induced acute kidney injury by targeting the CREB5/NF-κB signaling axis	22

VRK2 promotes colorectal cancer growth and impedes immunotherapy and 5-FU treatment efficacy	22
The curious case of mitochondrial sirtuin in rewiring breast cancer metabolism: Mr Hyde or Dr Jekyll?	22
Oleanonic acid ameliorates mutant Aβ precursor protein-induced oxidative stress, autophagy deficits, ferroptosis, mitochondrial damage, and ER stress in vitro	22
Lithocholic acid promotes rosacea-like skin inflammation via G protein-coupled bile acid receptor 1	22
Biological evaluation of novel dually-targeted metalloconjugates containing a PSMA inhibitor and a TPP group for prostate cancer theranostics	22
Amylin is incorporated into extracellular vesicles in an ESCRT-dependent manner and regulates senescence	22
Nicotinamide riboside kinase 2: A unique target for skeletal muscle and cardiometabolic diseases	22
Upregulation of GRP78 is accompanied by decreased antioxidant response and mitophagy promotion in streptozotocin-induced type 1 diabetes in rats	21
Proximal tubular Bmal1 protects against chronic kidney injury and renal fibrosis by maintaining of cellular metabolic homeostasis	21
CRISPR-Cas9 mediated knockout of NDUFS4 in human iPSCs: A model for mitochondrial complex I deficiency	21
Elevated senescence in the bone marrow mesenchymal stem cells of acquired aplastic anemia patients: A possible implication of DNA damage responses and telomere attrition	21
Plasma exosomes in obesity hypoventilation syndrome patients drive lung cancer cell malignant properties: Effect of long-term adherent CPAP treatment	21
Severe neonatal MEGDHEL syndrome with a homozygous truncating mutation in SERAC1	21
Interactions between daily sleep-wake rhythms, γ-secretase, and amyloid-β peptide pathology point to complex underlying relationships	21
Loss of YB-1 alleviates liver fibrosis by suppressing epithelial-mesenchymal transition in hepatic progenitor cells	21
Integration of proteomic and metabolomic analysis reveal distinct metabolic alterations of prostate cancer-associated fibroblasts compared to normal fibroblasts from patient's stroma samples	21
Inflammatory and tolerogenic dendritic cells and T lymphocytes in Graves' thyroidal and orbital disease	21
Integrated application of transcriptome and metabolomics reveals potential therapeutic targets for the polarization of atherosclerotic macrophages	21
PRDM15 promotes colorectal carcinogenesis by transcriptionally repressing USP10 to destabilize p53	20
Special issue - Mitochondria in aging, cancer and cell death	20
A disturbed metabolite-GPCR axis is associated with microbial dysbiosis in IBD patients: Potential role of GPR109A in macrophages	20
Carbon monoxide and mitochondria: Cell energy and fate control	20
MD2 mediates COPD pathogenesis by inducing airway inflammation and ferroptosis through the TLR4/MyD88 pathway	20
Endothelial cell-derived pro-fibrotic factors increase TGF-β1 expression by smooth muscle cells in response to cycles of hypoxia-hyperoxia	20
Micro-RNAs targeting the estrogen receptor alpha involved in endocrine therapy resistance in breast cancer	20
Remodeling of lipid landscape in high fat fed very-long chain acyl-CoA dehydrogenase null mice favors pro-arrhythmic polyunsaturated fatty acids and their downstream metabolites	20
Microglial pyroptosis drives neuropathic pain and targeting NLRP3 alleviates pain and neuroinflammation	20
An unusual signal transducer GIV/Girdin engages in the roles of adipocyte-derived hormone leptin in liver fibrosis	19
Mitochondria and Hypoxia Signalling	19
AOX delays the onset of the lethal phenotype in a mouse model of Uqcrh (complex III) disease	19
Mitochondrial turnover in neurodegeneration and ageing	19
Modern insights of nanotheranostics in the glioblastoma: An updated review	19
HIV and gp120-induced lipid droplets loss in hepatic stellate cells contribute to profibrotic profile	19
The role of mito-ribosomal fidelity in human disease: structural analysis of deafness-related mtDNA variants mapping to mitochondrial rRNA genes	19
A spectrum of AKT3 activating mutations cause focal malformations of cortical development (FMCDs) in cortical organoids	19
Phosphodiesterase 12 facilitates the growth and metastatic capabilities of gastric cancer cells by activating the TCAF2/JAK2/STAT3 axis	19
The E2 ubiquitin-conjugating enzyme HIP2 is a crucial regulator of quality control against mutant SOD1 proteotoxicity	18
SLP65/SLP76 Csk-interacting membrane protein promotes hepatic ischemia-reperfusion injury by activating TLR4/Erk1/2-mediated macrophages M1 polarization	18
Physical interaction between STAT3 and AP1 in cervical carcinogenesis: Implications in HPV transcription control	18
Intestinal microbiota-derived membrane vesicles and their role in chronic kidney disease	18
Over-activated hemichannels: A possible therapeutic target for human diseases	18
Upregulation of inflammatory genes and pathways links obesity to severe COVID-19	18
The contribution and therapeutic implications of IGHMBP2 mutations on IGHMBP2 biochemical activity and ABT1 association	18
Combined cryoablation and PD-1 inhibitor synergistically enhance antitumor immune responses in Lewis lung adenocarcinoma mice via the PI3K/AKT/mTOR pathway	18
Combined inhibition of EGFR and FGFRs with Cetuximab and Infigratinib showed effectiveness and relevance in proliferation and migration of HNSCC cell lines	18
PADI4 negatively regulates RIG-I-mediated antiviral response through deacetylation of IFN-β promoter via HDAC1	18
Immunometabolism and the modulation of immune responses and host defense: A role for methylglyoxal?	18
Aptamers against cancer drug resistance: Small fighters switching tactics in the face of defeat	17
Exploring the role and application of mitochondria in radiation therapy	17
Suppression of PCK1 attenuates neuronal injury and improves post-resuscitation outcomes	17
Editorial Board	17
Targeted inhibition of branched-chain amino acid metabolism drives apoptosis of glioblastoma by facilitating ubiquitin degradation of Mfn2 and oxidative stress	17
Proteomic- and metabolomic-based mechanisms of androgen-mediated right ventricular maladaptive remodeling under pressure overload	17
Unraveling the pathogenesis of viral-induced pulmonary arterial hypertension: Possible new therapeutic avenues with mesenchymal stromal cells and their derivatives.	17
Light deficiency in Apoe−/−mice increases atheroma plaque size and vulnerability by modulating local immunity	17
Hypoxic stress promotes astrocyte infiltration-like growth via HIF-1α/GDNF/LOXL2 axis	17
The IP3R inhibitor desmethylxestospongin B reduces tumor cell migration, invasion and metastasis by impairing lysosome acidification and β1-integrin recycling	17
Platelets promote metastasis of intrahepatic cholangiocarcinoma through activation of TGF-β/Smad2 pathway	17
Pannexin-2 deficiency disrupts visual pathways and leads to ocular defects in zebrafish	17
Immune infiltration related CENPI associates with the malignant features and drug resistance of lung adenocarcinoma	17
A dual sensing mechanism of eastern honeybee Apis cerana that upregulates the expression level of chemosensory protein CSP1 and enhances the binding affinity to loquat floral volatiles at low temperat	17
Role of acute exposure to environmental stressors in the gut-brain-periphery axis in the presence of cognitive resilience	17
Trained immunity in viral infections, Alzheimer's disease and multiple sclerosis: A convergence in type I interferon signalling and IFNβ-1a	17
WWOX: a promoter of brain mitochondrial dysfunction in a mouse model of type 2 diabetes	17
Discovery of 2,8-dihydroxyadenine in HUA patients with uroliths and biomarkers for its associated nephropathy	17
Dehydrozingerone ameliorates renal structure compromised in diabetic nephropathy	17
Icariin attenuates excessive alcohol consumption-induced susceptibility to atrial fibrillation through SIRT3 signaling	16
Adipocyte coculture induces a pro-inflammatory, fibrotic, angiogenic, and proliferative microenvironment in uterine leiomyoma cells	16
Caspase-3 and gasdermin E detection in peri-implantitis	16
Phytochemical strategies in glioblastoma therapy: Mechanisms, efficacy, and future perspectives	16
Editorial Board	16
Follicular CD8+ T cells promote immunoglobulin production and demyelination in multiple sclerosis and a murine model	16
Metabolic adaptations in cancer stem cells: A key to therapy resistance	16
An in-depth review of AI-powered advancements in cancer drug discovery	16
Prevotella copri ameliorates cholestasis and liver fibrosis in primary sclerosing cholangitis by enhancing the FXR signalling pathway	16
The ovine Type II Gaucher disease model recapitulates aspects of human brain disease.	16
Neuroinflammation in fetal alcohol spectrum disorders and related novel therapeutic approaches	16
The role of autophagy in the metabolism and differentiation of stem cells	16
Lamprey immunity protein enables early detection and recurrence monitoring for bladder cancer through recognizing Neu5Gc-modified uromodulin glycoprotein in urine	16
Aerobic exercise ameliorates insulin resistance in C57BL/6 J mice via activating Sestrin3	16

Integrated analysis of single-cell RNA-seq and bulk RNA-seq to unravel the molecular mechanisms underlying the immune microenvironment in the development of intestinal-type gastric cancer	15
Dysfunction of CCT3-associated network signals for the critical state during progression of hepatocellular carcinoma	15
Ncl liquid-liquid phase separation and SUMOylation mediate the stabilization of HIF-1α expression and promote pyroptosis in ischemic hindlimb	15
Impaired IL-27 signaling aggravates macrophage senescence and sensitizes premature ovarian insufficiency induction by high-fat diet	15
Suppression of intestinal Ticam1 ameliorated MASH via Akkermansia muciniphila QAA37749.1 mediated betaine transformation	15
Oxygen-sensitive Regulation of Mitochondrial Mass and its implication in the von Hippel-Lindau Syndrome	15
Adenine nucleotide translocase 2 silencing promotes metabolic reprogramming in P19 embryonal carcinoma stem cells	15
The (un)known crosstalk between metabolism and mechanotransduction: Implications for metabolic syndrome (MetS)-associated neurological complications	15
Electroacupuncture pre-treatment exerts a protective effect on LPS-induced cardiomyopathy in mice through the delivery of miR-381 via exosomes	15
Dihydroceramide desaturase modulates autolysosome maturation and ameliorates CRB1 retinopathy	15
Sfrp2 promotes renal dysfunction of diabetic kidney disease via modulating Fzd5-induced cytosolic calcium ion concentration and CaMKII/Mek/Erk pathway in mesangial cells	15
Identification of m6A modification patterns and RBM15 mediated macrophage phagocytosis in pancreatic cancer: An integrative analysis	15
Therapeutic potential of AAV-FL-Klotho in obesity: Impact on weight loss and lipid metabolism in mice	15
Loss of cytidine deaminase expression as a potential attempt to counteract the process of carcinogenesis by reducing basal PARP-1 activity and increasing tau levels	15
Extracellular RNAs/TLR3 signaling contributes to acute intestinal injury induced by intestinal ischemia reperfusion in mice	15
Metformin exposure during pregnancy and lactation affects offspring's long-term body weight and adipose tissue mass independent of the maternal metabolic state	14
IL-10 alleviates aTCMR by inhibiting NFATc1 signaling pathway of T cells after kidney transplantation	14
RASEF/Rab45 regulates the formation and sorting of zymogen granules and secretion of digestive enzymes by pancreatic acinar cells	14
Therapeutic targeting of HYPDH/PRODH2 with N-propargylglycine offers a Hyperoxaluria treatment opportunity	14
GPR68 supports AML cells through the calcium/calcineurin pro-survival pathway and confers chemoresistance by mediating glucose metabolic symbiosis	14
The microenvironment of secondary lymphedema. The key to finding effective treatments?	14
GBP1 promotes acute rejection after liver transplantation by inducing Kupffer cells pyroptosis	14
Epigenetics in autosomal dominant polycystic kidney disease	14
Targeting Ca2+-activated K+ channels in glioma	14
Autophagy unveiled: New horizons in health and disease	14
Metformin alleviates liver fibrosis in mice by enriching Lactobacillus sp. MF-1 in the gut microbiota	14
Mitochondrial classic metabolism and its often-underappreciated facets	14
Hyperglycemia and circadian disruption lead to retinal dysfunction in a stabilized colony of the fat sand rat Psammomys obesus	14
Melatonin and metformin ameliorated trastuzumab-induced cardiotoxicity through the modulation of mitochondrial function and dynamics without reducing its anticancer efficacy	14
Correlated with better prognosis, CSTA inhibits metastasis of nasopharyngeal carcinoma cells via suppressing AKT signaling through promoting METTL3 degradation	14
TNF-α drives bladder cancer metastasis via METTL3-mediated m6A modification to promote CLASP2/IQGAP1-dependent cytoskeleton remodeling	14
Toxoplasma gondii autophagy-related protein ATG7 maintains apicoplast inheritance by stabilizing and lipidating ATG8	14
Myo6 mediates osteoclast function and is essential for joint damage in collagen-induced arthritis	14
Identification of remodeled collagen fibers in tumor stroma by FTIR Micro-spectroscopy: A new approach to recognize the colon carcinoma	14
BCAR1 facilitates the survival of lung adenocarcinoma cells by augmenting the unfolded protein response, autophagy, and the formation of vasculogenic mimicry	14
A novel function of claudin-5 in maintaining the structural integrity of the heart and its implications in cardiac pathology	14
CTGF regulated by ATF6 inhibits vascular endothelial inflammation and reduces hepatic ischemia–reperfusion injury	14
Mechanism of multifunctional adaptor protein SHARPIN regulating myocardial fibrosis and how SNP mutation affect the prognosis of myocardial infarction	14
CXCL12 derived from CD248-expressing cancer-associated fibroblasts mediates M2-polarized macrophages to promote nonsmall cell lung cancer progression	13
The evil relationship between liver fibrosis and cardiovascular disease in metabolic dysfunction-associated fatty liver disease (MAFLD): Looking for the culprit	13
Editorial to special issue of BBADIS: Brain-gut interaction and cognitive control	13
Exosomes derived from periodontitis induce hepatic steatosis through the SCD-1/AMPK signaling pathway	13
The spike protein of SARS-CoV-2 induces heme oxygenase-1: Pathophysiologic implications	13
ETV4 and ETV1-mediated downregulation of the secretory leukocyte protease inhibitor contributes to the indolent phenotype of early-stage prostate cancer	13
Depletion of Mcpip1 in murine myeloid cells results in intestinal dysbiosis followed by allergic inflammation	13
Airway fibroblasts drive IL-4-mediated Th2 polarization in airway allergy: Mechanisms and therapeutic targeting	13
MicroRNA-126: A key regulator of angiogenesis, inflammation, and tumorigenesis — Exploring its multifaceted functions in vascular health and cancer	13
Downregulation of PGC-1α during cisplatin-induced muscle atrophy in murine skeletal muscle	13
Kinase library screening identifies IGF-1R as an oncogenic vulnerability in intrahepatic cholangiocarcinoma stem-like cells	13
IGF1R-α6 integrin-S100A4 network governs the organ-specific metastasis of chemoresistant epithelial ovarian cancer cells	13
Apigenin enhancing oxidative resistance and proteostasis to extend lifespan via PTEN-mediated AKT signalling pathway	13
SIRT6 controls hepatic lipogenesis by suppressing LXR, ChREBP, and SREBP1	13
Confrontation with kidney inflammation through a HMGB1-targeted peptide augments anti-fibrosis therapy	13
The Cellular Response to Hypoxia Depends on the Baseline Conditions: Normoxia versus Physioxia	13
Dapagliflozin attenuates AKI to CKD transition in diabetes by activating SIRT3/PGC1-α signaling and alleviating aberrant metabolic reprogramming	13
KDELR: Beyond protein retrieval, a novel regulator in cancer progression	13
Procollagen-lysine 2-oxoglutarate 5-dioxygenase 2 promotes collagen cross-linking and ECM stiffening to induce liver fibrosis	13
Copper induces liver lipotoxicity disease by up-regulating Nrf2 expression via the activation of MTF-1 and inhibition of SP1/Fyn pathway	13
Blood-based DNA methylation signatures in cancer: A systematic review	13
A prospective diagnostic and prognostic biomarker for hepatocellular carcinoma that functions in glucose metabolism regulation: Solute carrier family 37 member 3	13
Sex differences feed into nuclear receptor signaling along the digestive tract	13
Activation of IRF2 signaling networks facilitates podocyte pyroptosis in lupus nephritis	13
How does the natural compound 7α-acetoxy-6β-hydroxyroyleanone (Roy) modulates glioblastoma cells autophagy?	13
A genome wide screening to identify mediators of cellular senescence induced by loss of the mitochondrial fission protein Fis1	13
Increased NPM1 inhibit ferroptosis and aggravate renal fibrosis via Nrf2 pathway in chronic kidney disease	13
The in situ transcriptomic landscape of breast tumour-associated and normal adjacent endothelial cells	13
WTAP promotes macrophage recruitment and increases VEGF secretion via N6-methyladenosine modification in corneal neovascularization	12
Conditional Pten inactivation in pituitary results in sex-specific prolactinoma formation	12
Zika virus infection impairs synaptogenesis, induces neuroinflammation, and could be an environmental risk factor for autism spectrum disorder outcome	12
Inhibition of Mettl3 ameliorates osteoblastic senescence by mitigating m6A modifications on Slc1a5 via Igf2bp2-dependent mechanisms	12
Sports training improves motor function after spinal cord injury by regulating microtubule dynamics	12
Resistance exercise preconditioning prevents disuse muscle atrophy by inhibiting apoptosis and protein degradation via SESN2 in C57BL/6J mice	12
Loss of hepatocyte Usp53 protects mice from a form of xenobiotic-induced liver injury	12
Local modulation of thyroid hormone signaling in the retina affects the development of diabetic retinopathy	12
Clotrimazole presents anticancer properties against a mouse melanoma model acting as a PI3K inhibitor and inducing repolarization of tumor-associated macrophages	12
The mitochondrial signature of cultured endothelial cells in sepsis: Identifying potential targets for treatment	12
PGC-1α role in rescuing ferroptosis in cerebral ischemia/reperfusion injury through promoting mitochondrial biogenesis and UCP2 expression	12
Differential accumulation of human β-amyloid and tau from enriched extracts in neuronal and endothelial cells	12
Berberine chloride alleviated intestinal inflammation and improved postoperative ileus by regulating macrophage polarization via PI3K/AKT signaling pathway	12
Uterine leiomyoma as useful model to unveil morphometric and macromolecular collagen state and impairment in fibrotic diseases: An ex-vivo human study	12
Evolving perspectives regarding the role of the PD-1/PD-L1 pathway in gastric cancer immunotherapy	12
Estrogen receptor β attenuates renal fibrosis by suppressing the transcriptional activity of Smad3	12
Meteorin-like (METRNL) attenuates hypertensive induced cardiac hypertrophy by inhibiting autophagy via activating BRCA2	12
PRR promotes hypertensive renal injury by activating Wnt/β-catenin signaling and inflammation infiltration in mice	12
Cisplatin reduces immunosuppression caused by tumor-associated macrophages through downregulating CD47-SIRPα signaling in glioblastoma	12
Apolipoprotein E ε4 triggers neurotoxicity via cholesterol accumulation, acetylcholine dyshomeostasis, and PKCε mislocalization in cholinergic neuronal cells	12
Ertugliflozin attenuates atherosclerosis in nondiabetic ApoE−/− mice by upregulating ABCA1 and LDLR via the PPARγ/LXRα pathway	12
Therapeutic benefits of central LH receptor agonism in the APP/PS1 AD model involve trophic and immune regulation and are reproductive status dependent	12
Single-nucleus transcriptome profiling provides insights into the pathophysiology of adhesive arachnoiditis	12
The Annexin A2-Notch regulatory loop in hepatocytes promotes liver fibrosis in NAFLD by increasing osteopontin expression	12
P75NTR regulates autophagy through the YAP-mTOR pathway to increase the proliferation of interfollicular epidermal cells and promote wound healing in diabetic mice	12
CD36-mediated accumulation of MDSCs exerts abscopal immunosuppressive responses in hepatocellular carcinoma after insufficient microwave ablation	12
Orexin-A/OX1R is involved in regulation of autophagy to promote cortisol secretion in adrenocortical cell	11
Cell competition as an emerging mechanism and therapeutic target in cancer	11
Exploring new perspectives on congenital diaphragmatic hernia: A comprehensive review	11