Biochimica et Biophysica Acta-Molecular Basis of Disease

Papers
(The TQCC of Biochimica et Biophysica Acta-Molecular Basis of Disease is 11. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)
ArticleCitations
Editorial Board157
Abnormal interaction of Rlip with mutant APP/Abeta and phosphorylated tau reduces wild-type Rlip levels and disrupt Rlip function in Alzheimer's disease147
GEF-H1 drives breast cancer cells to tumor progression125
Hippocampal proteomic signatures of the ketogenic diet in a model of infantile epileptic spasms syndrome114
STRA13 exacerbates T2DM-induced diabetic cardiomyopathy by regulating the RXRα/UCP-1 signaling pathway114
Exploration of the role of mitochondria in reactive oxygen species generation under moderate hypoxia at the hippocampal CA3 area102
The effect of glutaminolysis inhibitors on in situ mitochondrial membrane potential70
Characterization of prokineticin system in Crohn's disease pathophysiology and pain, and its modulation by alcohol abuse: A preclinical study66
Lack of Cyclin E1 in hepatocytes aggravates ethanol-induced liver injury and hepatic steatosis in experimental murine model of acute and chronic alcohol-associated liver disease64
TAX1BP1 downregulation by STAT3 in cardiac fibroblasts contributes to diabetes-induced heart failure with preserved ejection fraction60
Corrigendum to “CRISPR/Cas9 genome editing demonstrates functionality of the autoimmunity-associated SNP rs12946510” [Biochim. Biophys. Acta (BBA) - Mol. Basis Dis. 1869 (2023) 166599]58
Corrigendum to “Small extracellular vesicles-mediated cellular interactions between tumor cells and tumor-associated macrophages: Implication for immunotherapy” [Biochim. Biophys. Acta (BBA) – Mol. Ba57
Functional characterisation of the ACE2 orthologues in Drosophila provides insights into the neuromuscular complications of COVID-1954
miR-653-3p promotes genomic instability of colorectal cancer cells via targeting SIRT1/TWIST1 signaling pathway51
FBXW8-mediated degradation of PPT1 suppresses epithelial-mesenchymal transition and metastasis in hepatocellular carcinoma50
ER stress modulated Klotho restoration: A prophylactic therapeutic strategy against acute kidney injury-diabetes comorbidity47
Dusp22 deficiency in cardiomyocytes exacerbates doxorubicin-induced cardiotoxicity by aggravating mitochondria-dependent apoptosis via JNK pathway47
The striking differences in the bioenergetics of brain and liver mitochondria are enhanced in mitochondrial disease47
Study on the synthesis, characterization, and antitumor mechanism investigation of QZQ-01115 via targeting sphingosine kinase 247
CD8+ T cell metabolic changes in breast cancer46
RGS1 can serve as a long-term prognostic marker in gastric cancer by promoting the infiltration and polarization of macrophages43
Editorial Board42
Gut-based manipulations spur hippocampal mitochondrial bioenergetics in a model of pediatric epilepsy42
FOXM1 promotes malignant biological behavior and metabolic reprogramming by targeting SPINK1 in hepatocellular carcinoma and affecting the p53 pathway42
ATP6V0d2 alleviates acute liver injury via promoting hepatocyte autophagy42
Sodium butyrate alleviates colitis by inhibiting mitochondrial ROS mediated macrophage pyroptosis41
Epigenetic regulation of autophagy in gastrointestinal cancers41
tp53 R217H and R242H mutant zebrafish exhibit dysfunctional p53 hallmarks and recapitulate Li-Fraumeni syndrome phenotypes40
The role of heart and neural crest derivatives-expressed protein factors in pregnancy39
Reduced parenteral glucose supply during neonatal infection attenuates neurological and renal pathology associated with modulation of innate and Th1 immunity38
UBE2K promotes breast cancer growth by ubiquitinating and degrading STUB1 to regulate the PKA/CREB1 signaling pathway, forming a feedback loop38
Role of elastic fiber degradation in disease pathogenesis37
Exploring ocular fibulin-3 (EFEMP1): Anatomical, age-related, and species perspectives37
Magnolol and Temozolomide exhibit a synergistic anti-glioma activity through MGMT inhibition37
STEAP3 alleviates inflammation and fibrosis via iron metabolism in ischemia/reperfusion-associated lung injury36
Necroptosis signaling and NLRP3 inflammasome cross-talking in epithelium facilitate Pseudomonas aeruginosa mediated lung injury36
Pharmacological inhibition of CFTR attenuates nonalcoholic steatohepatitis (NASH) progression in mice36
GLUT1 mediates the release of HMGB1 from airway epithelial cells in mixed granulocytic asthma36
Enhanced glycolysis by ATPIF1 gene inactivation increased the anti-bacterial activities of neutrophils through induction of ROS and lactic acid36
Fibroblast-specific MyD88-dependent signaling aggravates inflammation and cardiac dysfunction in the MI heart36
Senkyunolide I ameliorates thoracic aortic aneurysm and dissection in mice via inhibiting the oxidative stress and apoptosis of endothelial cells35
FGF21 at physiological concentrations regulates vascular endothelial cell function through multiple pathways35
Targeting the reprogrammed metabolism in H3.3K27M pediatric high-grade gliomas34
Exercise-induced irisin attenuates ferroptosis in polycystic ovary syndrome by modulating the NCOA4-FTH pathway33
Endocytic trafficking of connexins in cancer pathogenesis33
IFN-γ-responsiveness of lymphatic endothelial cells inhibits melanoma lymphatic dissemination via AMPK-mediated metabolic control33
Potential protective role of let-7d-5p in atherosclerosis progression reducing the inflammatory pathway regulated by NF-κB and vascular smooth muscle cells proliferation33
The paradox of fatty-acid β-oxidation in muscle insulin resistance: Metabolic control and muscle heterogeneity33
Endotoxin-induced m6A RNA methylation landscape in lung endothelial cells: role of METTL3 in regulating inflammation and injury during acute lung injury32
Indole-3 propionate inhibits NF-κB/NLRP3-mediated osteoclastogenesis and improves bone quality in high-fat-diet induced obese mice32
Experimental and clinical perspectives on glycocalyx integrity and its relation to acute respiratory distress syndrome32
Biological evaluation of novel dually-targeted metalloconjugates containing a PSMA inhibitor and a TPP group for prostate cancer theranostics31
Miro1 role in intra- and inter-cellular mitochondrial movement in tumour microenvironment31
Editorial Board31
Cytotoxic profile of naturally occurring abietane diterpenoids in urothelial carcinoma cells31
Special issue - Mitochondria in aging, cancer and cell death31
Normal urinary oxalate excretion in 4-hydroxy-2-oxo-glutarate aldolase 1 (HOGA1) deficient mice with AGT expression in peroxisomes and not in mitochondria31
IKZF1 promotes pyroptosis and prevents M2 macrophage polarization by inhibiting JAK2/STAT5 pathway in colon cancer31
Impaired mitochondrial metabolism and ER-mitochondria contact sites affect signaling in cancer cells31
NAT2 activity increases cytotoxicity of anthracycline antibiotics and HDAC inhibitors31
Sex-Specific Impact of Maternal Obesity and Gestational Exercise on Offspring's Cardiac Health: Insights into Mitochondrial Function and NO Signaling31
Inflammatory and tolerogenic dendritic cells and T lymphocytes in Graves' thyroidal and orbital disease30
Serinc2 antagonizes pressure overload-induced cardiac hypertrophy via regulating the amino acid/mTORC1 signaling pathway30
Corrigendum to paper entitled “Seronegative patients with primary Sjogren's syndrome and non-pSS sicca test positive for anti-SSA/Ro52 and -Ro60 in saliva” [Published in: BBA – Mol. Basis Dis. Volume 30
ETS1 and RBPJ transcriptionally regulate METTL14 to suppress TGF-β1-induced epithelial-mesenchymal transition in human bronchial epithelial cells30
Integrated multiomic analysis identifies TRIP13 as a mediator of alveolar epithelial type II cell dysfunction in idiopathic pulmonary fibrosis30
Corrigendum to “Polycystin-1 downregulation induces ERK-dependent mTOR pathway activation in a cellular model of psoriasis” [BBA – Mol. Basis Dis. 1864 (2018) 3468–3476]30
Identification of m6A-related biomarkers in Kawasaki disease30
Amylin is incorporated into extracellular vesicles in an ESCRT-dependent manner and regulates senescence29
Association of proteomics with lymph node metastasis in early gastric cancer patients28
Integrated application of transcriptome and metabolomics reveals potential therapeutic targets for the polarization of atherosclerotic macrophages28
Remodeling of lipid landscape in high fat fed very-long chain acyl-CoA dehydrogenase null mice favors pro-arrhythmic polyunsaturated fatty acids and their downstream metabolites28
Plasma exosomes in obesity hypoventilation syndrome patients drive lung cancer cell malignant properties: Effect of long-term adherent CPAP treatment28
Oleanonic acid ameliorates mutant Aβ precursor protein-induced oxidative stress, autophagy deficits, ferroptosis, mitochondrial damage, and ER stress in vitro28
RhFGF21 protects the skin from UVB irradiation in diabetic mice through the inhibition of epidermal cell apoptosis and macrophage-mediated inflammation via the SIRT1 signaling pathway27
Programmed cell death protein 5 inhibits hepatocellular carcinoma progression by inducing pyroptosis through regulation of TGF-β/Smad2/3/Snail pathway27
PRDM15 promotes colorectal carcinogenesis by transcriptionally repressing USP10 to destabilize p5327
A novel causative role of imbalanced kynurenine pathway in ulcerative colitis: Upregulation of KMO and KYNU promotes intestinal inflammation27
A disturbed metabolite-GPCR axis is associated with microbial dysbiosis in IBD patients: Potential role of GPR109A in macrophages27
CRISPR-Cas9 mediated knockout of NDUFS4 in human iPSCs: A model for mitochondrial complex I deficiency26
Cholesterol redistribution triggered by CYP46A1 gene therapy improves major hallmarks of Niemann-Pick type C disease but is not sufficient to halt neurodegeneration26
Carbon monoxide and mitochondria: Cell energy and fate control26
Integration of proteomic and metabolomic analysis reveal distinct metabolic alterations of prostate cancer-associated fibroblasts compared to normal fibroblasts from patient's stroma samples26
The curious case of mitochondrial sirtuin in rewiring breast cancer metabolism: Mr Hyde or Dr Jekyll?26
Pathogenesis of mtDNA point mutation m.10191T>C affecting complex I function is a multifactorial process leading to metabolic remodeling of mitochondria26
FOXQ1, deubiquitinated by USP10, alleviates sepsis-induced acute kidney injury by targeting the CREB5/NF-κB signaling axis26
Loss of USP22 alleviates cardiac hypertrophy induced by pressure overload through HiF1-α-TAK1 signaling pathway26
Microglia toxicology in α-synuclein pathology25
Nicotinamide riboside kinase 2: A unique target for skeletal muscle and cardiometabolic diseases25
MD2 mediates COPD pathogenesis by inducing airway inflammation and ferroptosis through the TLR4/MyD88 pathway25
HIF1α/PRDX1 axis drives pulmonary vascular remodeling through DRP1 DeSUMOylation and mitochondrial fragmentation25
Reactive oxygen species in colorectal cancer adjuvant therapies25
Elevated senescence in the bone marrow mesenchymal stem cells of acquired aplastic anemia patients: A possible implication of DNA damage responses and telomere attrition24
Upregulation of GRP78 is accompanied by decreased antioxidant response and mitophagy promotion in streptozotocin-induced type 1 diabetes in rats24
Proximal tubular Bmal1 protects against chronic kidney injury and renal fibrosis by maintaining of cellular metabolic homeostasis24
Microglial pyroptosis drives neuropathic pain and targeting NLRP3 alleviates pain and neuroinflammation24
Unravelling the impact of QRICH1 modulation on endoplasmic reticulum stress and neuronal apoptosis in traumatic brain injury24
Leptin/PPARγ interaction mediates obesity-driven Th17 differentiation in rheumatoid arthritis24
Lithocholic acid promotes rosacea-like skin inflammation via G protein-coupled bile acid receptor 124
Interactions between daily sleep-wake rhythms, γ-secretase, and amyloid-β peptide pathology point to complex underlying relationships24
Loss of YB-1 alleviates liver fibrosis by suppressing epithelial-mesenchymal transition in hepatic progenitor cells24
VRK2 promotes colorectal cancer growth and impedes immunotherapy and 5-FU treatment efficacy24
Hypoxic stress promotes astrocyte infiltration-like growth via HIF-1α/GDNF/LOXL2 axis23
SLP65/SLP76 Csk-interacting membrane protein promotes hepatic ischemia-reperfusion injury by activating TLR4/Erk1/2-mediated macrophages M1 polarization23
Modern insights of nanotheranostics in the glioblastoma: An updated review23
The IP3R inhibitor desmethylxestospongin B reduces tumor cell migration, invasion and metastasis by impairing lysosome acidification and β1-integrin recycling23
A dual sensing mechanism of eastern honeybee Apis cerana that upregulates the expression level of chemosensory protein CSP1 and enhances the binding affinity to loquat floral volatiles at low temperat23
Targeted inhibition of branched-chain amino acid metabolism drives apoptosis of glioblastoma by facilitating ubiquitin degradation of Mfn2 and oxidative stress23
Icariin attenuates excessive alcohol consumption-induced susceptibility to atrial fibrillation through SIRT3 signaling23
The contribution and therapeutic implications of IGHMBP2 mutations on IGHMBP2 biochemical activity and ABT1 association23
Role of acute exposure to environmental stressors in the gut-brain-periphery axis in the presence of cognitive resilience23
AOX delays the onset of the lethal phenotype in a mouse model of Uqcrh (complex III) disease22
The ovine Type II Gaucher disease model recapitulates aspects of human brain disease.22
An unusual signal transducer GIV/Girdin engages in the roles of adipocyte-derived hormone leptin in liver fibrosis22
Editorial Board22
An in-depth review of AI-powered advancements in cancer drug discovery22
Editorial Board22
Editorial Board21
Micro-RNAs targeting the estrogen receptor alpha involved in endocrine therapy resistance in breast cancer21
Mitochondria and Hypoxia Signalling21
Vimentin-targeting adaptogen withaferin A: Potential to selectively suppress cervical cancer – Single-cell microspectroscopic and molecular analysis21
Light deficiency in Apoe−/−mice increases atheroma plaque size and vulnerability by modulating local immunity21
Mitochondrial turnover in neurodegeneration and ageing21
WWOX: a promoter of brain mitochondrial dysfunction in a mouse model of type 2 diabetes21
Unraveling the pathogenesis of viral-induced pulmonary arterial hypertension: Possible new therapeutic avenues with mesenchymal stromal cells and their derivatives.21
Proteomic- and metabolomic-based mechanisms of androgen-mediated right ventricular maladaptive remodeling under pressure overload21
The role of mito-ribosomal fidelity in human disease: structural analysis of deafness-related mtDNA variants mapping to mitochondrial rRNA genes21
Discovery of 2,8-dihydroxyadenine in HUA patients with uroliths and biomarkers for its associated nephropathy21
Follicular CD8+ T cells promote immunoglobulin production and demyelination in multiple sclerosis and a murine model20
Suppression of PCK1 attenuates neuronal injury and improves post-resuscitation outcomes20
Upregulation of inflammatory genes and pathways links obesity to severe COVID-1920
Intestinal microbiota-derived membrane vesicles and their role in chronic kidney disease20
Therapeutic potential of AAV-FL-Klotho in obesity: Impact on weight loss and lipid metabolism in mice20
HIV and gp120-induced lipid droplets loss in hepatic stellate cells contribute to profibrotic profile20
Exploring the role and application of mitochondria in radiation therapy20
The role of autophagy in the metabolism and differentiation of stem cells20
Dehydrozingerone ameliorates renal structure compromised in diabetic nephropathy20
Domain-specific mechanisms of YAP1 variants in ocular coloboma revealed by in-vitro and organoid studies20
Dysfunction of CCT3-associated network signals for the critical state during progression of hepatocellular carcinoma20
PADI4 negatively regulates RIG-I-mediated antiviral response through deacetylation of IFN-β promoter via HDAC120
Aerobic exercise ameliorates insulin resistance in C57BL/6 J mice via activating Sestrin320
Trained immunity in viral infections, Alzheimer's disease and multiple sclerosis: A convergence in type I interferon signalling and IFNβ-1a20
A spectrum of AKT3 activating mutations cause focal malformations of cortical development (FMCDs) in cortical organoids20
Adipocyte coculture induces a pro-inflammatory, fibrotic, angiogenic, and proliferative microenvironment in uterine leiomyoma cells19
Identification of m6A modification patterns and RBM15 mediated macrophage phagocytosis in pancreatic cancer: An integrative analysis19
Metabolic adaptations in cancer stem cells: A key to therapy resistance19
Pannexin-2 deficiency disrupts visual pathways and leads to ocular defects in zebrafish19
Immunometabolism and the modulation of immune responses and host defense: A role for methylglyoxal?19
Dapagliflozin targets RORγt to improve myocardial ischemia-reperfusion injury-induced heart failure by regulating the CD4+ T cell/Th17 cell axis within cardiac tissue19
Sfrp2 promotes renal dysfunction of diabetic kidney disease via modulating Fzd5-induced cytosolic calcium ion concentration and CaMKII/Mek/Erk pathway in mesangial cells19
12,13-diHOME ameliorates MASLD by regulating Sestrin2-mediated AMPK/ULK1/Lipophagy in obese mice19
Lamprey immunity protein enables early detection and recurrence monitoring for bladder cancer through recognizing Neu5Gc-modified uromodulin glycoprotein in urine19
Vitamin D attenuates PCSK9-driven phenotypic switch of vascular smooth muscle cells and neointimal hyperplasia via SIRT6 activation19
Physical interaction between STAT3 and AP1 in cervical carcinogenesis: Implications in HPV transcription control19
Platelets promote metastasis of intrahepatic cholangiocarcinoma through activation of TGF-β/Smad2 pathway19
Aptamers against cancer drug resistance: Small fighters switching tactics in the face of defeat19
Adenine nucleotide translocase 2 silencing promotes metabolic reprogramming in P19 embryonal carcinoma stem cells19
Integrated analysis of single-cell RNA-seq and bulk RNA-seq to unravel the molecular mechanisms underlying the immune microenvironment in the development of intestinal-type gastric cancer19
Combined inhibition of EGFR and FGFRs with Cetuximab and Infigratinib showed effectiveness and relevance in proliferation and migration of HNSCC cell lines18
Immune infiltration related CENPI associates with the malignant features and drug resistance of lung adenocarcinoma18
Dihydroceramide desaturase modulates autolysosome maturation and ameliorates CRB1 retinopathy18
GBP1 promotes acute rejection after liver transplantation by inducing Kupffer cells pyroptosis18
Kinase library screening identifies IGF-1R as an oncogenic vulnerability in intrahepatic cholangiocarcinoma stem-like cells18
Loss of cytidine deaminase expression as a potential attempt to counteract the process of carcinogenesis by reducing basal PARP-1 activity and increasing tau levels18
Autophagy unveiled: New horizons in health and disease18
Phytochemical strategies in glioblastoma therapy: Mechanisms, efficacy, and future perspectives18
Oxygen-sensitive Regulation of Mitochondrial Mass and its implication in the von Hippel-Lindau Syndrome18
Neuroinflammation in fetal alcohol spectrum disorders and related novel therapeutic approaches18
IL-10 alleviates aTCMR by inhibiting NFATc1 signaling pathway of T cells after kidney transplantation18
Airway fibroblasts drive IL-4-mediated Th2 polarization in airway allergy: Mechanisms and therapeutic targeting18
Combined cryoablation and PD-1 inhibitor synergistically enhance antitumor immune responses in Lewis lung adenocarcinoma mice via the PI3K/AKT/mTOR pathway18
Phosphodiesterase 12 facilitates the growth and metastatic capabilities of gastric cancer cells by activating the TCAF2/JAK2/STAT3 axis18
Transcriptomic analysis reveals heart failure-related lncRNA LINC00670 as a regulator of colon cancer mesenchymal genes18
Electroacupuncture pre-treatment exerts a protective effect on LPS-induced cardiomyopathy in mice through the delivery of miR-381 via exosomes18
Mechanism of multifunctional adaptor protein SHARPIN regulating myocardial fibrosis and how SNP mutation affect the prognosis of myocardial infarction18
Myo6 mediates osteoclast function and is essential for joint damage in collagen-induced arthritis18
GPR68 supports AML cells through the calcium/calcineurin pro-survival pathway and confers chemoresistance by mediating glucose metabolic symbiosis17
Hyperglycemia and circadian disruption lead to retinal dysfunction in a stabilized colony of the fat sand rat Psammomys obesus17
BCAR1 facilitates the survival of lung adenocarcinoma cells by augmenting the unfolded protein response, autophagy, and the formation of vasculogenic mimicry17
CTGF regulated by ATF6 inhibits vascular endothelial inflammation and reduces hepatic ischemia–reperfusion injury17
Activation of IRF2 signaling networks facilitates podocyte pyroptosis in lupus nephritis17
Dapagliflozin attenuates AKI to CKD transition in diabetes by activating SIRT3/PGC1-α signaling and alleviating aberrant metabolic reprogramming17
Microglial GLUL loss worsens TBI outcomes by amplifying the arginine-citrulline pathway17
Heterogeneous nuclear ribonucleoprotein C deficiency compromises extracellular matrix-receptor interaction and induces apoptosis in esophageal cancer by targeting transcripts with complex structures17
Extracellular RNAs/TLR3 signaling contributes to acute intestinal injury induced by intestinal ischemia reperfusion in mice17
KDELR: Beyond protein retrieval, a novel regulator in cancer progression17
Ncl liquid-liquid phase separation and SUMOylation mediate the stabilization of HIF-1α expression and promote pyroptosis in ischemic hindlimb17
The evil relationship between liver fibrosis and cardiovascular disease in metabolic dysfunction-associated fatty liver disease (MAFLD): Looking for the culprit17
Correlated with better prognosis, CSTA inhibits metastasis of nasopharyngeal carcinoma cells via suppressing AKT signaling through promoting METTL3 degradation17
Atractylenolide I ameliorates acute-on-chronic liver failure (ACLF) by promoting autophagy and preserving mitochondrial function through mTOR inhibition17
Impaired IL-27 signaling aggravates macrophage senescence and sensitizes premature ovarian insufficiency induction by high-fat diet17
A novel function of claudin-5 in maintaining the structural integrity of the heart and its implications in cardiac pathology17
Epigenetics in autosomal dominant polycystic kidney disease17
Therapeutic targeting of HYPDH/PRODH2 with N-propargylglycine offers a Hyperoxaluria treatment opportunity17
TNF-α drives bladder cancer metastasis via METTL3-mediated m6A modification to promote CLASP2/IQGAP1-dependent cytoskeleton remodeling17
Targeting Ca2+-activated K+ channels in glioma16
Increased NPM1 inhibit ferroptosis and aggravate renal fibrosis via Nrf2 pathway in chronic kidney disease16
A prospective diagnostic and prognostic biomarker for hepatocellular carcinoma that functions in glucose metabolism regulation: Solute carrier family 37 member 316
MAIT cells accumulated via CXCL12-CXCR4 chemotaxis are involved in pathologic gastric inflammation among Helicobacter pylori-infected patients16
Metformin exposure during pregnancy and lactation affects offspring's long-term body weight and adipose tissue mass independent of the maternal metabolic state16
Blood-based DNA methylation signatures in cancer: A systematic review16
Apigenin enhancing oxidative resistance and proteostasis to extend lifespan via PTEN-mediated AKT signalling pathway16
Dysregulation of the CUL2-Sirt2 axis exacerbates lung epithelial barrier injury in Staphylococcus aureus-induced pneumonia16
ETV4 and ETV1-mediated downregulation of the secretory leukocyte protease inhibitor contributes to the indolent phenotype of early-stage prostate cancer16
Cdc42 signaling regulated by dopamine D2 receptor correlatively links specific brain regions of hippocampus to cocaine addiction16
Exosomes derived from periodontitis induce hepatic steatosis through the SCD-1/AMPK signaling pathway16
Differential accumulation of human β-amyloid and tau from enriched extracts in neuronal and endothelial cells16
Downregulation of PGC-1α during cisplatin-induced muscle atrophy in murine skeletal muscle16
Metformin alleviates liver fibrosis in mice by enriching Lactobacillus sp. MF-1 in the gut microbiota16
Copper induces liver lipotoxicity disease by up-regulating Nrf2 expression via the activation of MTF-1 and inhibition of SP1/Fyn pathway16
Mitochondrial classic metabolism and its often-underappreciated facets16
Procollagen-lysine 2-oxoglutarate 5-dioxygenase 2 promotes collagen cross-linking and ECM stiffening to induce liver fibrosis16
RASEF/Rab45 regulates the formation and sorting of zymogen granules and secretion of digestive enzymes by pancreatic acinar cells16
Melatonin and metformin ameliorated trastuzumab-induced cardiotoxicity through the modulation of mitochondrial function and dynamics without reducing its anticancer efficacy16
WITHDRAWN: Corrigendum to “NADPH oxidase 5 promotes adhesion and infiltration of immune cells in the brain. Implications in ischemic stroke” [Biochim. Biophys. Acta (BBA) - Mol. Basis Dis. (2026) volu16
PRR promotes hypertensive renal injury by activating Wnt/β-catenin signaling and inflammation infiltration in mice16
EGR2 promotes vascular smooth muscle cell differentiation and proliferation in outward remodeling during arteriovenous fistula maturation16
The microenvironment of secondary lymphedema. The key to finding effective treatments?16
Suppression of intestinal Ticam1 ameliorated MASH via Akkermansia muciniphila QAA37749.1 mediated betaine transformation16
Toxoplasma gondii autophagy-related protein ATG7 maintains apicoplast inheritance by stabilizing and lipidating ATG816
The (un)known crosstalk between metabolism and mechanotransduction: Implications for metabolic syndrome (MetS)-associated neurological complications16
MicroRNA-126: A key regulator of angiogenesis, inflammation, and tumorigenesis — Exploring its multifaceted functions in vascular health and cancer16
CXCL12 derived from CD248-expressing cancer-associated fibroblasts mediates M2-polarized macrophages to promote nonsmall cell lung cancer progression16
Single-nucleus transcriptome profiling provides insights into the pathophysiology of adhesive arachnoiditis16
Protein kinase D: A therapeutic target in experimental alcoholic pancreatitis16
Berberine chloride alleviated intestinal inflammation and improved postoperative ileus by regulating macrophage polarization via PI3K/AKT signaling pathway16
Therapeutic benefits of central LH receptor agonism in the APP/PS1 AD model involve trophic and immune regulation and are reproductive status dependent15
The in situ transcriptomic landscape of breast tumour-associated and normal adjacent endothelial cells15
Evolving perspectives regarding the role of the PD-1/PD-L1 pathway in gastric cancer immunotherapy15
Depletion of Mcpip1 in murine myeloid cells results in intestinal dysbiosis followed by allergic inflammation15
Ertugliflozin attenuates atherosclerosis in nondiabetic ApoE−/− mice by upregulating ABCA1 and LDLR via the PPARγ/LXRα pathway15
Deubiquitylase PSMD14 inhibits autophagy to promote ovarian cancer progression via stabilization of LRPPRC15
Inhibition of Mettl3 ameliorates osteoblastic senescence by mitigating m6A modifications on Slc1a5 via Igf2bp2-dependent mechanisms15
The Annexin A2-Notch regulatory loop in hepatocytes promotes liver fibrosis in NAFLD by increasing osteopontin expression15
Exploring the pleiotropic effects of lncRNA in different repeat expansion disorders15
Zika virus infection triggers the melanization response in Drosophila15
Genetic alterations in SUPT6H are associated with neurodevelopmental disorders15
De novo CSDE1 missense variant T595N regulates miRNA expression in a patient with a complex neurodevelopmental condition15
Meteorin-like (METRNL) attenuates hypertensive induced cardiac hypertrophy by inhibiting autophagy via activating BRCA215
Osteopontin aggravates myocardial fibrosis by promoting phenotypic transition of cardiac fibroblasts via Hippo-YAP pathway15
PGC-1α role in rescuing ferroptosis in cerebral ischemia/reperfusion injury through promoting mitochondrial biogenesis and UCP2 expression15
Zika virus infection impairs synaptogenesis, induces neuroinflammation, and could be an environmental risk factor for autism spectrum disorder outcome15
Resistance exercise preconditioning prevents disuse muscle atrophy by inhibiting apoptosis and protein degradation via SESN2 in C57BL/6J mice15
Loss of hepatocyte Usp53 protects mice from a form of xenobiotic-induced liver injury15
Editorial Board15
Hypoxia induced deregulation of sphingolipids in colon cancer is a prognostic marker for patient outcome15
Sports training improves motor function after spinal cord injury by regulating microtubule dynamics15
Expression of Concern: “Direct antioxidant and protective effect of estradiol on isolated mitochondria” [Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2010, Volume 1802, Issue 1, P15
High-fat diet does not exacerbate aortic pathology and enhances metabolic function in Marfan syndrome Fbn1C1041G/+ mice15
Molecular and cellular impact of a C203R/C198R M-opsin mutation15
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