Biochimica et Biophysica Acta-Molecular Basis of Disease

Papers
(The TQCC of Biochimica et Biophysica Acta-Molecular Basis of Disease is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)
ArticleCitations
Magnolol and Temozolomide exhibit a synergistic anti-glioma activity through MGMT inhibition140
Identification and characterization of two novel melanocortin-3 receptor mutations in Chinese obese individuals133
Editorial Board121
TAX1BP1 downregulation by STAT3 in cardiac fibroblasts contributes to diabetes-induced heart failure with preserved ejection fraction100
Dietary fats modulate neuroinflammation in mucin 2 knock out mice model of spontaneous colitis100
Lack of Cyclin E1 in hepatocytes aggravates ethanol-induced liver injury and hepatic steatosis in experimental murine model of acute and chronic alcohol-associated liver disease86
Abnormal interaction of Rlip with mutant APP/Abeta and phosphorylated tau reduces wild-type Rlip levels and disrupt Rlip function in Alzheimer's disease80
Characterization of prokineticin system in Crohn's disease pathophysiology and pain, and its modulation by alcohol abuse: A preclinical study80
Functional characterisation of the ACE2 orthologues in Drosophila provides insights into the neuromuscular complications of COVID-1977
Editorial Board72
Exploration of the role of mitochondria in reactive oxygen species generation under moderate hypoxia at the hippocampal CA3 area64
The effect of glutaminolysis inhibitors on in situ mitochondrial membrane potential63
Gut-based manipulations spur hippocampal mitochondrial bioenergetics in a model of pediatric epilepsy59
Corrigendum to “CRISPR/Cas9 genome editing demonstrates functionality of the autoimmunity-associated SNP rs12946510” [Biochim. Biophys. Acta (BBA) - Mol. Basis Dis. 1869 (2023) 166599]58
Exploring ocular fibulin-3 (EFEMP1): Anatomical, age-related, and species perspectives57
Experimental and clinical perspectives on glycocalyx integrity and its relation to acute respiratory distress syndrome54
CD8+ T cell metabolic changes in breast cancer54
RGS1 can serve as a long-term prognostic marker in gastric cancer by promoting the infiltration and polarization of macrophages51
Reduced parenteral glucose supply during neonatal infection attenuates neurological and renal pathology associated with modulation of innate and Th1 immunity49
IFN-γ-responsiveness of lymphatic endothelial cells inhibits melanoma lymphatic dissemination via AMPK-mediated metabolic control45
miR-653-3p promotes genomic instability of colorectal cancer cells via targeting SIRT1/TWIST1 signaling pathway42
Sodium butyrate alleviates colitis by inhibiting mitochondrial ROS mediated macrophage pyroptosis38
GEF-H1 drives breast cancer cells to tumor progression37
Necroptosis signaling and NLRP3 inflammasome cross-talking in epithelium facilitate Pseudomonas aeruginosa mediated lung injury36
Pharmacological inhibition of CFTR attenuates nonalcoholic steatohepatitis (NASH) progression in mice36
Endocytic trafficking of connexins in cancer pathogenesis36
Potential protective role of let-7d-5p in atherosclerosis progression reducing the inflammatory pathway regulated by NF-κB and vascular smooth muscle cells proliferation35
The paradox of fatty-acid β-oxidation in muscle insulin resistance: Metabolic control and muscle heterogeneity34
Targeting the reprogrammed metabolism in H3.3K27M pediatric high-grade gliomas33
Recognition of asymptomatic hypercholanemia of pregnancy: Different clinical features, fetal outcomes and bile acids metabolism from intrahepatic cholestasis of pregnancy33
Splice variants of metabolic nuclear receptors: Relevance for metabolic disease and therapeutic targeting32
Fibroblast-specific MyD88-dependent signaling aggravates inflammation and cardiac dysfunction in the MI heart32
The striking differences in the bioenergetics of brain and liver mitochondria are enhanced in mitochondrial disease32
The role of heart and neural crest derivatives-expressed protein factors in pregnancy32
Pentacyclic triterpene oleanolic acid protects against cardiac aging through regulation of mitophagy and mitochondrial integrity32
FOXM1 promotes malignant biological behavior and metabolic reprogramming by targeting SPINK1 in hepatocellular carcinoma and affecting the p53 pathway31
IKZF1 promotes pyroptosis and prevents M2 macrophage polarization by inhibiting JAK2/STAT5 pathway in colon cancer30
Epigenetic regulation of autophagy in gastrointestinal cancers30
Senkyunolide I ameliorates thoracic aortic aneurysm and dissection in mice via inhibiting the oxidative stress and apoptosis of endothelial cells30
Role of elastic fiber degradation in disease pathogenesis30
GLUT1 mediates the release of HMGB1 from airway epithelial cells in mixed granulocytic asthma30
FGF21 at physiological concentrations regulates vascular endothelial cell function through multiple pathways30
Enhanced glycolysis by ATPIF1 gene inactivation increased the anti-bacterial activities of neutrophils through induction of ROS and lactic acid30
ER stress modulated Klotho restoration: A prophylactic therapeutic strategy against acute kidney injury-diabetes comorbidity30
tp53 R217H and R242H mutant zebrafish exhibit dysfunctional p53 hallmarks and recapitulate Li-Fraumeni syndrome phenotypes30
Pregnancy and pandemics: Interaction of viral surface proteins and placenta cells30
Corrigendum to “Small extracellular vesicles-mediated cellular interactions between tumor cells and tumor-associated macrophages: Implication for immunotherapy” [Biochim. Biophys. Acta (BBA) – Mol. Ba30
RhFGF21 protects the skin from UVB irradiation in diabetic mice through the inhibition of epidermal cell apoptosis and macrophage-mediated inflammation via the SIRT1 signaling pathway29
Upregulation of GRP78 is accompanied by decreased antioxidant response and mitophagy promotion in streptozotocin-induced type 1 diabetes in rats28
Carbon monoxide and mitochondria: Cell energy and fate control27
Association of proteomics with lymph node metastasis in early gastric cancer patients27
ETS1 and RBPJ transcriptionally regulate METTL14 to suppress TGF-β1-induced epithelial-mesenchymal transition in human bronchial epithelial cells27
Identification of m6A-related biomarkers in Kawasaki disease27
CRISPR-Cas9 mediated knockout of NDUFS4 in human iPSCs: A model for mitochondrial complex I deficiency26
NAT2 activity increases cytotoxicity of anthracycline antibiotics and HDAC inhibitors26
Miro1 role in intra- and inter-cellular mitochondrial movement in tumour microenvironment25
A disturbed metabolite-GPCR axis is associated with microbial dysbiosis in IBD patients: Potential role of GPR109A in macrophages25
Integration of proteomic and metabolomic analysis reveal distinct metabolic alterations of prostate cancer-associated fibroblasts compared to normal fibroblasts from patient's stroma samples25
VRK2 promotes colorectal cancer growth and impedes immunotherapy and 5-FU treatment efficacy25
Corrigendum to paper entitled “Seronegative patients with primary Sjogren's syndrome and non-pSS sicca test positive for anti-SSA/Ro52 and -Ro60 in saliva” [Published in: BBA – Mol. Basis Dis. Volume 25
Loss of USP22 alleviates cardiac hypertrophy induced by pressure overload through HiF1-α-TAK1 signaling pathway25
Loss of YB-1 alleviates liver fibrosis by suppressing epithelial-mesenchymal transition in hepatic progenitor cells25
Editorial Board24
Sex-Specific Impact of Maternal Obesity and Gestational Exercise on Offspring's Cardiac Health: Insights into Mitochondrial Function and NO Signaling24
Impaired mitochondrial metabolism and ER-mitochondria contact sites affect signaling in cancer cells24
Cytotoxic profile of naturally occurring abietane diterpenoids in urothelial carcinoma cells24
Cholesterol redistribution triggered by CYP46A1 gene therapy improves major hallmarks of Niemann-Pick type C disease but is not sufficient to halt neurodegeneration23
Amylin is incorporated into extracellular vesicles in an ESCRT-dependent manner and regulates senescence23
Severe neonatal MEGDHEL syndrome with a homozygous truncating mutation in SERAC123
Endothelial cell-derived pro-fibrotic factors increase TGF-β1 expression by smooth muscle cells in response to cycles of hypoxia-hyperoxia23
Microglia toxicology in α-synuclein pathology22
Oleanonic acid ameliorates mutant Aβ precursor protein-induced oxidative stress, autophagy deficits, ferroptosis, mitochondrial damage, and ER stress in vitro22
Microglial pyroptosis drives neuropathic pain and targeting NLRP3 alleviates pain and neuroinflammation22
Biological evaluation of novel dually-targeted metalloconjugates containing a PSMA inhibitor and a TPP group for prostate cancer theranostics22
Nicotinamide riboside kinase 2: A unique target for skeletal muscle and cardiometabolic diseases22
A novel causative role of imbalanced kynurenine pathway in ulcerative colitis: Upregulation of KMO and KYNU promotes intestinal inflammation21
Serinc2 antagonizes pressure overload-induced cardiac hypertrophy via regulating the amino acid/mTORC1 signaling pathway20
Integrated application of transcriptome and metabolomics reveals potential therapeutic targets for the polarization of atherosclerotic macrophages20
Integrated multiomic analysis identifies TRIP13 as a mediator of alveolar epithelial type II cell dysfunction in idiopathic pulmonary fibrosis20
The curious case of mitochondrial sirtuin in rewiring breast cancer metabolism: Mr Hyde or Dr Jekyll?20
Plasma exosomes in obesity hypoventilation syndrome patients drive lung cancer cell malignant properties: Effect of long-term adherent CPAP treatment20
Elevated senescence in the bone marrow mesenchymal stem cells of acquired aplastic anemia patients: A possible implication of DNA damage responses and telomere attrition20
Unravelling the impact of QRICH1 modulation on endoplasmic reticulum stress and neuronal apoptosis in traumatic brain injury20
FOXQ1, deubiquitinated by USP10, alleviates sepsis-induced acute kidney injury by targeting the CREB5/NF-κB signaling axis20
Proximal tubular Bmal1 protects against chronic kidney injury and renal fibrosis by maintaining of cellular metabolic homeostasis20
Remodeling of lipid landscape in high fat fed very-long chain acyl-CoA dehydrogenase null mice favors pro-arrhythmic polyunsaturated fatty acids and their downstream metabolites20
Programmed cell death protein 5 inhibits hepatocellular carcinoma progression by inducing pyroptosis through regulation of TGF-β/Smad2/3/Snail pathway20
Lithocholic acid promotes rosacea-like skin inflammation via G protein-coupled bile acid receptor 119
A spectrum of AKT3 activating mutations cause focal malformations of cortical development (FMCDs) in cortical organoids19
Reactive oxygen species in colorectal cancer adjuvant therapies19
Mitochondrial turnover in neurodegeneration and ageing19
Mitochondria and Hypoxia Signalling19
Inflammatory and tolerogenic dendritic cells and T lymphocytes in Graves' thyroidal and orbital disease19
Corrigendum to “Polycystin-1 downregulation induces ERK-dependent mTOR pathway activation in a cellular model of psoriasis” [BBA – Mol. Basis Dis. 1864 (2018) 3468–3476]19
The role of mito-ribosomal fidelity in human disease: structural analysis of deafness-related mtDNA variants mapping to mitochondrial rRNA genes18
Proteomic- and metabolomic-based mechanisms of androgen-mediated right ventricular maladaptive remodeling under pressure overload18
The contribution and therapeutic implications of IGHMBP2 mutations on IGHMBP2 biochemical activity and ABT1 association18
HIV and gp120-induced lipid droplets loss in hepatic stellate cells contribute to profibrotic profile18
Pannexin-2 deficiency disrupts visual pathways and leads to ocular defects in zebrafish18
Follicular CD8+ T cells promote immunoglobulin production and demyelination in multiple sclerosis and a murine model18
PADI4 negatively regulates RIG-I-mediated antiviral response through deacetylation of IFN-β promoter via HDAC118
Light deficiency in Apoe−/−mice increases atheroma plaque size and vulnerability by modulating local immunity18
Role of acute exposure to environmental stressors in the gut-brain-periphery axis in the presence of cognitive resilience18
Micro-RNAs targeting the estrogen receptor alpha involved in endocrine therapy resistance in breast cancer18
Combined cryoablation and PD-1 inhibitor synergistically enhance antitumor immune responses in Lewis lung adenocarcinoma mice via the PI3K/AKT/mTOR pathway18
Discovery of 2,8-dihydroxyadenine in HUA patients with uroliths and biomarkers for its associated nephropathy17
Adipocyte coculture induces a pro-inflammatory, fibrotic, angiogenic, and proliferative microenvironment in uterine leiomyoma cells17
Editorial Board17
Lamprey immunity protein enables early detection and recurrence monitoring for bladder cancer through recognizing Neu5Gc-modified uromodulin glycoprotein in urine17
Dysfunction of CCT3-associated network signals for the critical state during progression of hepatocellular carcinoma17
Caspase-3 and gasdermin E detection in peri-implantitis17
The E2 ubiquitin-conjugating enzyme HIP2 is a crucial regulator of quality control against mutant SOD1 proteotoxicity16
Over-activated hemichannels: A possible therapeutic target for human diseases16
An unusual signal transducer GIV/Girdin engages in the roles of adipocyte-derived hormone leptin in liver fibrosis16
Physical interaction between STAT3 and AP1 in cervical carcinogenesis: Implications in HPV transcription control16
Editorial Board16
The ovine Type II Gaucher disease model recapitulates aspects of human brain disease.16
Immunometabolism and the modulation of immune responses and host defense: A role for methylglyoxal?16
The role of autophagy in the metabolism and differentiation of stem cells16
Trained immunity in viral infections, Alzheimer's disease and multiple sclerosis: A convergence in type I interferon signalling and IFNβ-1a16
The IP3R inhibitor desmethylxestospongin B reduces tumor cell migration, invasion and metastasis by impairing lysosome acidification and β1-integrin recycling16
Sfrp2 promotes renal dysfunction of diabetic kidney disease via modulating Fzd5-induced cytosolic calcium ion concentration and CaMKII/Mek/Erk pathway in mesangial cells16
Unraveling the pathogenesis of viral-induced pulmonary arterial hypertension: Possible new therapeutic avenues with mesenchymal stromal cells and their derivatives.15
Intestinal microbiota-derived membrane vesicles and their role in chronic kidney disease15
Exploring the role and application of mitochondria in radiation therapy15
Modern insights of nanotheranostics in the glioblastoma: An updated review15
Contribution of podocyte inflammatory exosome release to glomerular inflammation and sclerosis during hyperhomocysteinemia15
WWOX: a promoter of brain mitochondrial dysfunction in a mouse model of type 2 diabetes15
Upregulation of inflammatory genes and pathways links obesity to severe COVID-1915
Identification of m6A modification patterns and RBM15 mediated macrophage phagocytosis in pancreatic cancer: An integrative analysis15
Suppression of PCK1 attenuates neuronal injury and improves post-resuscitation outcomes15
Neuroinflammation in fetal alcohol spectrum disorders and related novel therapeutic approaches15
Phytochemical strategies in glioblastoma therapy: Mechanisms, efficacy, and future perspectives15
Platelets promote metastasis of intrahepatic cholangiocarcinoma through activation of TGF-β/Smad2 pathway15
Immune infiltration related CENPI associates with the malignant features and drug resistance of lung adenocarcinoma15
Hypoxic stress promotes astrocyte infiltration-like growth via HIF-1α/GDNF/LOXL2 axis15
A dual sensing mechanism of eastern honeybee Apis cerana that upregulates the expression level of chemosensory protein CSP1 and enhances the binding affinity to loquat floral volatiles at low temperat15
An in-depth review of AI-powered advancements in cancer drug discovery15
Aptamers against cancer drug resistance: Small fighters switching tactics in the face of defeat14
BCAR1 facilitates the survival of lung adenocarcinoma cells by augmenting the unfolded protein response, autophagy, and the formation of vasculogenic mimicry14
GPR68 supports AML cells through the calcium/calcineurin pro-survival pathway and confers chemoresistance by mediating glucose metabolic symbiosis14
Editorial to special issue of BBADIS: Brain-gut interaction and cognitive control14
Combined inhibition of EGFR and FGFRs with Cetuximab and Infigratinib showed effectiveness and relevance in proliferation and migration of HNSCC cell lines14
Prevotella copri ameliorates cholestasis and liver fibrosis in primary sclerosing cholangitis by enhancing the FXR signalling pathway14
Targeted inhibition of branched-chain amino acid metabolism drives apoptosis of glioblastoma by facilitating ubiquitin degradation of Mfn2 and oxidative stress14
Metabolic adaptations in cancer stem cells: A key to therapy resistance14
Oxygen-sensitive Regulation of Mitochondrial Mass and its implication in the von Hippel-Lindau Syndrome14
Downregulation of PGC-1α during cisplatin-induced muscle atrophy in murine skeletal muscle14
A prospective diagnostic and prognostic biomarker for hepatocellular carcinoma that functions in glucose metabolism regulation: Solute carrier family 37 member 314
Therapeutic potential of AAV-FL-Klotho in obesity: Impact on weight loss and lipid metabolism in mice14
AOX delays the onset of the lethal phenotype in a mouse model of Uqcrh (complex III) disease14
Integrated analysis of single-cell RNA-seq and bulk RNA-seq to unravel the molecular mechanisms underlying the immune microenvironment in the development of intestinal-type gastric cancer14
Autophagy unveiled: New horizons in health and disease14
Ncl liquid-liquid phase separation and SUMOylation mediate the stabilization of HIF-1α expression and promote pyroptosis in ischemic hindlimb14
Growth impairment, increased placental glucose uptake and altered transplacental transport in VIP deficient pregnancies: Maternal vs. placental contributions14
Icariin attenuates excessive alcohol consumption-induced susceptibility to atrial fibrillation through SIRT3 signaling14
Aerobic exercise ameliorates insulin resistance in C57BL/6 J mice via activating Sestrin314
Hyperglycemia and circadian disruption lead to retinal dysfunction in a stabilized colony of the fat sand rat Psammomys obesus13
Mechanism of multifunctional adaptor protein SHARPIN regulating myocardial fibrosis and how SNP mutation affect the prognosis of myocardial infarction13
TNF-α drives bladder cancer metastasis via METTL3-mediated m6A modification to promote CLASP2/IQGAP1-dependent cytoskeleton remodeling13
Extracellular RNAs/TLR3 signaling contributes to acute intestinal injury induced by intestinal ischemia reperfusion in mice13
Sex differences feed into nuclear receptor signaling along the digestive tract13
Exosomes derived from periodontitis induce hepatic steatosis through the SCD-1/AMPK signaling pathway13
CTGF regulated by ATF6 inhibits vascular endothelial inflammation and reduces hepatic ischemia–reperfusion injury13
The spike protein of SARS-CoV-2 induces heme oxygenase-1: Pathophysiologic implications13
Myo6 mediates osteoclast function and is essential for joint damage in collagen-induced arthritis13
Increased NPM1 inhibit ferroptosis and aggravate renal fibrosis via Nrf2 pathway in chronic kidney disease13
Dihydroceramide desaturase modulates autolysosome maturation and ameliorates CRB1 retinopathy13
Metformin exposure during pregnancy and lactation affects offspring's long-term body weight and adipose tissue mass independent of the maternal metabolic state13
Identification of remodeled collagen fibers in tumor stroma by FTIR Micro-spectroscopy: A new approach to recognize the colon carcinoma13
Impaired IL-27 signaling aggravates macrophage senescence and sensitizes premature ovarian insufficiency induction by high-fat diet13
Blood-based DNA methylation signatures in cancer: A systematic review13
Toxoplasma gondii autophagy-related protein ATG7 maintains apicoplast inheritance by stabilizing and lipidating ATG813
Suppression of intestinal Ticam1 ameliorated MASH via Akkermansia muciniphila QAA37749.1 mediated betaine transformation12
SIRT6 controls hepatic lipogenesis by suppressing LXR, ChREBP, and SREBP112
Epigenetics in autosomal dominant polycystic kidney disease12
Kinase library screening identifies IGF-1R as an oncogenic vulnerability in intrahepatic cholangiocarcinoma stem-like cells12
Melatonin and metformin ameliorated trastuzumab-induced cardiotoxicity through the modulation of mitochondrial function and dynamics without reducing its anticancer efficacy12
Therapeutic targeting of HYPDH/PRODH2 with N-propargylglycine offers a Hyperoxaluria treatment opportunity12
IGF1R-α6 integrin-S100A4 network governs the organ-specific metastasis of chemoresistant epithelial ovarian cancer cells12
The microenvironment of secondary lymphedema. The key to finding effective treatments?12
Metformin alleviates liver fibrosis in mice by enriching Lactobacillus sp. MF-1 in the gut microbiota12
Apigenin enhancing oxidative resistance and proteostasis to extend lifespan via PTEN-mediated AKT signalling pathway12
Dapagliflozin attenuates AKI to CKD transition in diabetes by activating SIRT3/PGC1-α signaling and alleviating aberrant metabolic reprogramming12
Correlated with better prognosis, CSTA inhibits metastasis of nasopharyngeal carcinoma cells via suppressing AKT signaling through promoting METTL3 degradation12
The evil relationship between liver fibrosis and cardiovascular disease in metabolic dysfunction-associated fatty liver disease (MAFLD): Looking for the culprit12
A novel function of claudin-5 in maintaining the structural integrity of the heart and its implications in cardiac pathology12
RASEF/Rab45 regulates the formation and sorting of zymogen granules and secretion of digestive enzymes by pancreatic acinar cells12
CXCL12 derived from CD248-expressing cancer-associated fibroblasts mediates M2-polarized macrophages to promote nonsmall cell lung cancer progression12
Copper induces liver lipotoxicity disease by up-regulating Nrf2 expression via the activation of MTF-1 and inhibition of SP1/Fyn pathway12
GBP1 promotes acute rejection after liver transplantation by inducing Kupffer cells pyroptosis12
The (un)known crosstalk between metabolism and mechanotransduction: Implications for metabolic syndrome (MetS)-associated neurological complications12
Absence of MMACHC in peripheral retinal cells does not lead to an ocular phenotype in mice12
Procollagen-lysine 2-oxoglutarate 5-dioxygenase 2 promotes collagen cross-linking and ECM stiffening to induce liver fibrosis12
The protective effect of forsythiaside A on 3,5-diethoxycarbonyl-1,4-dihydrocollidine-induced cholestatic liver injury in mice: Based on targeted metabolomics and molecular biology technology11
The Annexin A2-Notch regulatory loop in hepatocytes promotes liver fibrosis in NAFLD by increasing osteopontin expression11
Cdc42 signaling regulated by dopamine D2 receptor correlatively links specific brain regions of hippocampus to cocaine addiction11
Conditional Pten inactivation in pituitary results in sex-specific prolactinoma formation11
PRR promotes hypertensive renal injury by activating Wnt/β-catenin signaling and inflammation infiltration in mice11
Loss of cytidine deaminase expression as a potential attempt to counteract the process of carcinogenesis by reducing basal PARP-1 activity and increasing tau levels11
Local modulation of thyroid hormone signaling in the retina affects the development of diabetic retinopathy11
Zika virus infection triggers the melanization response in Drosophila11
Rapid diagnosis of malignant pleural mesothelioma and its discrimination from lung cancer and benign exudative effusions using blood serum11
Resistance exercise preconditioning prevents disuse muscle atrophy by inhibiting apoptosis and protein degradation via SESN2 in C57BL/6J mice11
Mechanisms and repair strategies for white matter degeneration in CNS injury and diseases11
Nuclear factor of activated T-cells (NFAT) regulation of IL-1β-induced retinal vascular inflammation11
A genome wide screening to identify mediators of cellular senescence induced by loss of the mitochondrial fission protein Fis111
Confrontation with kidney inflammation through a HMGB1-targeted peptide augments anti-fibrosis therapy11
An emerging role of the 5′ termini of mature tRNAs in human diseases: Current situation and prospects11
Editorial Board11
Electroacupuncture pre-treatment exerts a protective effect on LPS-induced cardiomyopathy in mice through the delivery of miR-381 via exosomes11
P75NTR regulates autophagy through the YAP-mTOR pathway to increase the proliferation of interfollicular epidermal cells and promote wound healing in diabetic mice11
The xenobiotic receptors PXR and CAR in liver physiology, an update11
Protein kinase D: A therapeutic target in experimental alcoholic pancreatitis11
Gamut of glycolytic enzymes in vascular smooth muscle cell proliferation: Implications for vascular proliferative diseases11
Meteorin-like (METRNL) attenuates hypertensive induced cardiac hypertrophy by inhibiting autophagy via activating BRCA211
Phosphorylated TAR DNA-binding protein-43: Aggregation and antibody-based inhibition11
Apolipoprotein E ε4 triggers neurotoxicity via cholesterol accumulation, acetylcholine dyshomeostasis, and PKCε mislocalization in cholinergic neuronal cells11
How does the natural compound 7α-acetoxy-6β-hydroxyroyleanone (Roy) modulates glioblastoma cells autophagy?11
Hypoxia induced deregulation of sphingolipids in colon cancer is a prognostic marker for patient outcome11
The in situ transcriptomic landscape of breast tumour-associated and normal adjacent endothelial cells11
The Cellular Response to Hypoxia Depends on the Baseline Conditions: Normoxia versus Physioxia11
The mitochondrial signature of cultured endothelial cells in sepsis: Identifying potential targets for treatment11
Depletion of Mcpip1 in murine myeloid cells results in intestinal dysbiosis followed by allergic inflammation11
Clusterin in Alzheimer's disease: An amyloidogenic inhibitor of amyloid formation?11
Uterine leiomyoma as useful model to unveil morphometric and macromolecular collagen state and impairment in fibrotic diseases: An ex-vivo human study11
CD36-mediated accumulation of MDSCs exerts abscopal immunosuppressive responses in hepatocellular carcinoma after insufficient microwave ablation11
NPC1-like phenotype, with intracellular cholesterol accumulation and altered mTORC1 signaling in models of Parkinson's disease10
PURA and GLUT1: Sweet partners for brain health10
Lessons from microRNA biology: Top key cellular drivers of Autosomal Dominant Polycystic Kidney Disease10
Retraction notice to “Leptin attenuates BACE1 expression and amyloid-β genesis via the activation of SIRT1 signaling pathway” [Biochim. Biophys. Acta (BBA) - Mol. Basis Dis. 1842 (2014) 1587–1595]10
Activation, interaction and intimation of Nrf2 pathway and their mutational studies causing Nrf2 associated cancer10
Hepatic HKDC1 deletion alleviates western diet-induced MASH in mice10
Exploring new perspectives on congenital diaphragmatic hernia: A comprehensive review10
Accumulation of β-aminoisobutyric acid mediates hyperalgesia in ovariectomized mice through Mas-related G protein-coupled receptor D signaling10
Inhibition of Mettl3 ameliorates osteoblastic senescence by mitigating m6A modifications on Slc1a5 via Igf2bp2-dependent mechanisms10
Deep multi-omics integration approach reveals new molecular features of uterine leiomyosarcoma10
Targeted regulation of autophagy using nanoparticles: New insight into cancer therapy10
Co-targeting of ACK1 and KIT triggers additive anti-proliferative and -migration effects in imatinib-resistant gastrointestinal stromal tumors10
Amyloid pathology reduces ELP3 expression and tRNA modifications leading to impaired proteostasis10
EREG silencing inhibits tumorigenesis via inactivating ERK/p38 MAPK pathway in pancreatic ductal adenocarcinoma10
Helicobacter pylori promotes epithelial-to-mesenchymal transition by downregulating CK2β in gastric cancer cells10
Cell competition as an emerging mechanism and therapeutic target in cancer10
Orexin-A/OX1R is involved in regulation of autophagy to promote cortisol secretion in adrenocortical cell10
Potential mechanisms underlying the promoting effects of 3D collagen scaffold culture on stemness and drug resistance of glioma cells10
NF-κB and EGFR participate in S1PR3-mediated human renal cell carcinomas progression10
Tadalafil enhances the therapeutic efficacy of BET inhibitors in hepatocellular carcinoma through activating Hippo pathway10
Loss of Fic causes progressive neurodegeneration in a Drosophila model of hereditary spastic paraplegia10
HIV in pregnancy: Mother-to-child transmission, pharmacotherapy, and toxicity10
CD36 inhibition corrects lipid-FetuinA mediated insulin secretory defects by preventing intracellular lipid accumulation and inflammation in the pancreatic beta cells10
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