Cancer Gene Therapy

Papers
(The median citation count of Cancer Gene Therapy is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)
ArticleCitations
Reducing the risks of nuclear war—the role of health professionals141
Use of CRISPR-based screens to identify mechanisms of chemotherapy resistance136
Defining treatment-resistant brain cancer: Genetic screening to identify oncogene-driven immunomodulation and therapy resistance132
Correction to: Identification of a five genes prognosis signature for triple-negative breast cancer using multi-omics methods and bioinformatics analysis126
Platelet activation: a barrier to effective antitumor immunity79
ADAM12 expression is upregulated in cancer cells upon radiation and constitutes a prognostic factor in rectal cancer patients following radiotherapy78
Characteristics and developmental trajectory of clinical trials focused on tumor-infiltrating lymphocytes for cancer treatment70
Small extracellular vesicle TGF-β in cancer progression and immune evasion67
Circ-GSK3B up-regulates GSK3B to suppress the progression of lung adenocarcinoma65
Application of CAR-T therapy in solid tumors: current opportunities and challenges60
P38 kinase in gastrointestinal cancers54
Lysine-40 succinylation of TAGLN2 induces glioma angiogenesis and tumor growth through regulating TMSB4X48
Ending nuclear weapons, before they end us48
Role of non-coding RNAs in neuroblastoma47
Pan-cancer oncogenic properties and therapeutic potential of SF3B445
Long noncoding RNA EPCART regulates translation through PI3K/AKT/mTOR pathway and PDCD4 in prostate cancer45
Targeting TLK2 inhibits the progression of gastric cancer by reprogramming amino acid metabolism through the mTOR/ASNS axis42
Unveiling the role of the extracellular matrix in the osteosarcoma tumor microenvironment through integrated transcriptomics and experimental validation38
PDPN contributes to constructing immunosuppressive microenvironment in IDH wildtype glioma37
Viral vectors and extracellular vesicles: innate delivery systems utilized in CRISPR/Cas-mediated cancer therapy37
Self-replicating messenger RNA based cancer immunotherapy36
NRAV promotes HCC stemness via the m6A-regulated let-7c-5p/LIN28B axis36
CircPKN2 promotes ferroptosis in bladder cancer by promoting the ubiquitination of Stearoyl-CoA Desaturase 135
TNFRSF19 promotes endoplasmic reticulum stress-induced paraptosis via the activation of the MAPK pathway in triple-negative breast cancer cells34
TRPM8 promotes hepatocellular carcinoma progression by inducing SNORA55 mediated nuclear-mitochondrial communication31
Correction to: Lycium barbarum glycopeptide targets PER2 to inhibit lipogenesis in glioblastoma by downregulating SREBP1c31
circXRCC5 foster gastric cancer growth and metastasis by the HNRNPC/circXRCC5/miR-655-3p/RREB1/UBA2 positive feedback loop31
Exploring RNA biology in pseudomyxoma peritonei uncovers splicing dysregulation as a novel, targetable molecular vulnerability30
BCL-xL dependency in chromophobe renal cell carcinoma30
Real-world outcomes of Adjuvant De Gramont versus Xelox chemotherapy in reSected gasTric cancER: a propensity score-matched analysis (ASTER study)30
Bacillus Calmette-Guerin induces CD8+ T cell infiltration and suppresses tumor progression in microsatellite stable colorectal cancer by downregulating ARID1A29
Single-cell atlas reveals the immunosuppressive microenvironment and Treg cells landscapes in recurrent Glioblastoma28
The target atlas for antibody-drug conjugates across solid cancers28
Targeted inactivation of EWSR1 : : FLI1 gene in Ewing sarcoma via CRISPR/Cas9 driven by an Ewing-specific GGAA promoter28
LncRNA CALML3-AS1 modulated by m6A modification induces BTNL9 methylation to drive non-small-cell lung cancer progression27
CDK5RAP3 acts as a tumour suppressor in gastric cancer through the infiltration and polarization of tumour-associated macrophages27
WTAP stabilized by USP7 contributes to enzalutamide resistance in prostate cancer via mediating AKT m6A-modification26
Identification of HDAC4 as a potential therapeutic target and prognostic biomarker for ZFTA-fused ependymomas26
Manipulating the tumour immune microenvironment by N6-methyladenosine RNA modification25
SMAD4-armed oncolytic adenovirus therapy potentiates the chemotherapy effects in NSCLC through suppression of the Wnt/β-catenin pathway25
LOXL1-AS1 inhibits JAK2 ubiquitination and promotes cholangiocarcinoma progression through JAK2/STAT3 signaling24
A conditionally replicative adenovirus vector containing the synNotch receptor gene for the treatment of muscle-invasive bladder cancer24
CAR T cells as micropharmacies against solid cancers: Combining effector T-cell mediated cell death with vascular targeting in a one-step engineering process24
The FOSB-IGFBP5-IGF-1 axis: a novel regulatory pathway that suppresses prostate cancer growth23
EZH1/2 as targets for cancer therapy23
Editorial Expression of Concern: p73β-expressing recombinant adenovirus: a potential anticancer agent23
NRF2-SOX4 complex regulates PSPH in hepatocellular carcinoma and modulates M2 macrophage differentiation23
Editorial Expression of Concern: E1A-induced apoptosis does not prevent replication of adenoviruses with deletion of E1b in majority of infected cancer cells23
Nogo-B receptor increases glycolysis and the paclitaxel resistance of estrogen receptor-positive breast cancer via the HIF-1α-dependent pathway22
Retraction Note: Overexpressed transient receptor potential vanilloid 1 (TRPV1) in lung adenocarcinoma harbours a new opportunity for therapeutic targeting22
Circular RNA RHBDD1 regulates tumorigenicity and ferroptosis in colorectal cancer by mediating the ELAVL1/SCD mRNA interaction22
AAV-mediated combination gene therapy of inducible Caspase 9 and miR-199a-5p is therapeutic in hepatocellular carcinoma21
m6A-modified circABCC4 promotes stemness and metastasis of prostate cancer by recruiting IGF2BP2 to increase stability of CCAR121
Biodistribution and toxicity evaluation of oncolytic adenovirus Adf35(OGN) in Syrian hamster and mouse20
Knock-out of 5-lipoxygenase in overexpressing tumor cells—consequences on gene expression and cellular function20
Suppression of FOXO1 activity by SIRT1-mediated deacetylation weakening the intratumoral androgen autocrine function in glioblastoma20
IER3: exploring its dual function as an oncogene and tumor suppressor20
Chimeric Ad5/35 oncolytic adenovirus overcome preexisting neutralizing antibodies and enhance tumor targeting efficiency20
BETA prime: a first-in-man phase 1 study of AdAPT-001, an armed oncolytic adenovirus for solid tumors20
Landscape and functional impact of variants of unknown significance of immune response genes in human cancer20
Arsenic trioxide and p97 inhibitor synergize against acute myeloid leukemia by targeting nascent polypeptides and activating the ZAKα–JNK pathway20
Reversible downregulation of MYC in a spheroid model of metastatic epithelial ovarian cancer19
A guardian turned rogue: TP53 promoter translocations rewire stress responses to oncogenic effectors in osteosarcoma19
Glimmers of hope for targeting oncogenic KRAS-G12D19
HIF-1α/IL-8 axis in hypoxic macrophages promotes esophageal cancer progression by enhancing PD-L1 expression19
ECT2 promotes malignant phenotypes through the activation of the AKT/mTOR pathway and cisplatin resistance in cervical cancer19
p53-regulated lncRNAs in cancers: from proliferation and metastasis to therapy19
Hidden patterns of gene expression provide prognostic insight for colorectal cancer19
Tumor-derived ARHGAP35 mutations enhance the Gα13-Rho signaling axis in human endometrial cancer19
METTL3 promotes the malignancy of non-small cell lung cancer by N6-methyladenosine modifying SFRP218
Intraperitoneal administration of adeno-associated virus encoding microRNA-29b for the treatment of peritoneal metastasis18
Pleiotropic mechanisms of cancer-associated fibroblast-mediated resistance in hepatocellular carcinoma: emerging therapeutic vulnerabilities and targeting strategies18
Extracellular vesicles released by glioma cells are decorated by Annexin A2 allowing for cellular uptake via heparan sulfate18
Structural regulation of PLK1 activity: implications for cell cycle function and drug discovery18
Blocking tri-methylguanosine synthase 1 (TGS1) stops anchorage-independent growth of canine sarcomas18
TFF3 sensitizes cervical carcinoma cells to cisplatin toxicity by binding to IGF2R17
CASC4/GOLM2 drives high grade serous carcinoma anoikis resistance through the recycling of EGFR17
Effective delivery of genome editor to cervical cancer targeting Mcl1 for cancer therapy17
CRISPR-Cas gene knockouts to optimize engineered T cells for cancer immunotherapy17
Transactivation of Met signaling by oncogenic Gnaq drives the evolution of melanoma in Hgf-Cdk4 mice17
Therapeutic potential of synthetic microRNA mimics based on the miR-15/107 consensus sequence17
Proteomic profiling reveals ACSS2 facilitating metabolic support in acute myeloid leukemia17
Utilizing nullomers in cell-free RNA for early cancer detection16
FOXM1 promotes neurofibromatosis type 1-associated malignant peripheral nerve sheath tumor progression in a NUF2-dependent manner16
WWOX binds MERIT40 and modulates its function in homologous recombination, implications in breast cancer16
An alternative fully human anti-BCMA CAR-T shows response for relapsed or refractory multiple myeloma with anti-BCMA CAR-T exposures previously16
SOCS3 inhibiting JAK-STAT pathway enhances oncolytic adenovirus efficacy by potentiating viral replication and T-cell activation16
SPP1+ TAM subpopulations in tumor microenvironment promote intravasation and metastasis of head and neck squamous cell carcinoma16
Integrating system biology and intratumor gene therapy by trans-complementing the appropriate co-stimulatory molecule as payload in oncolytic herpes virus15
Gastrointestinal infections and gastrointestinal haemorrhage are underestimated but serious adverse events in chimeric antigen receptor T-cell recipients: A real-world study15
TSPAN1 inhibits metastasis of nasopharyngeal carcinoma via suppressing NF-kB signaling15
RevCAR-expressing immune effector cells for targeting of Fn14-positive glioblastoma15
Correction to: Single-cell RNA sequencing reveals changes in glioma-associated macrophage polarization and cellular states of malignant gliomas with high AQP4 expression15
GPR107: A key driver of breast cancer invasion and metastasis through collagen IV modulation15
Correction: Arsenic trioxide and p97 inhibitor synergize against acute myeloid leukemia by targeting nascent polypeptides and activating the ZAKα–JNK pathway15
Long noncoding RNA LINC00173 induces radioresistance in nasopharyngeal carcinoma via inhibiting CHK2/P53 pathway14
STAT5a and SH2B3 novel mutations display malignancy roles in a triple-negative primary myelofibrosis patient14
Clathrin-associated SCYL2 contributes to the activation of PI3K/AKT signaling and tumorigenesis through PTEN phosphorylation in adult T-cell leukemia/lymphoma14
The long-term effectiveness and mechanism of oncolytic virotherapy combined with anti-PD-L1 antibody in colorectal cancer patient14
GLIPR1 promotes proliferation, metastasis and 5-fluorouracil resistance in hepatocellular carcinoma by activating the PI3K/PDK1/ROCK1 pathway14
HPV status represents dominant trait driving delineation of survival-associated gene co-expression networks in head and neck cancer14
MBD1 protects replication fork stability by recruiting PARP1 and controlling transcription-replication conflicts14
Integration of humanized ROBO1 CAR in PD-1 locus in natural killer cells delivers synergistic tumor-killing effect against non-small cell lung cancer14
MALNC: a new mutant NPM1/IDH2R140 and PML-RARA-associated lncRNA with impact on AML cell proliferation, maturation and drug response14
Correction to: Nogo-B receptor increases glycolysis and the paclitaxel resistance of estrogen receptor-positive breast cancer via the HIF-1α-dependent pathway14
Detection of (pre)cancerous colorectal lesions in Lynch syndrome patients by microsatellite instability liquid biopsy14
Global characterization of megakaryocytes in bone marrow, peripheral blood, and cord blood by single-cell RNA sequencing14
Lipid-related FABP5 activation of tumor-associated monocytes fosters immune privilege via PD-L1 expression on Treg cells in hepatocellular carcinoma13
Regional infusion of a class C TLR9 agonist enhances liver tumor microenvironment reprogramming and MDSC reduction to improve responsiveness to systemic checkpoint inhibition13
Identification of lineage-specific epigenetic regulators FOXA1 and GRHL2 through chromatin accessibility profiling in breast cancer cell lines13
Clonal dynamics limits detection of selection in tumour xenograft CRISPR/Cas9 screens13
Engineered L-asparaginase variants with enhanced therapeutic properties to improve treatment of childhood acute lymphatic leukemia13
Activating NRF2E79Q mutation alters the differentiation of human non-small cell lung cancer13
SPARC family proteins: matricellular modulators of cancer progression and therapeutic resistance13
A novel intranasal peptide vaccine inhibits non-small cell lung cancer with KRAS mutation13
Estrogen receptor status heterogeneity in breast cancer tumor: role in response to endocrine treatment13
Retraction Note: microRNA-133a exerts tumor suppressive role in oral squamous cell carcinoma through the Notch signaling pathway via downregulation of CTBP213
Activation of CEACAM1 with an agonistic monoclonal antibody results in inhibition of melanoma cells13
Cell-intrinsic platinum response and associated genetic and gene expression signatures in ovarian cancer13
Microbiota in tumors: new factor influencing cancer development13
GAS5 attenuates the malignant progression of glioma stem-like cells by promoting E-cadherin13
Anti-angiogenesis and anti-immunosuppression gene therapy through targeting COUP-TFII in an in situ glioblastoma mouse model12
Integrated multidimensional bioinformatics analysis of the molecular mechanisms of ulcerative colitis-associated colorectal cancer and MMP1 as a potential therapeutic target12
Correction: Pan-cancer oncogenic properties and therapeutic potential of SF3B412
Anti-leukemia effects of omipalisib in acute myeloid leukemia: inhibition of PI3K/AKT/mTOR signaling and suppression of mitochondrial biogenesis12
Long non-coding RNAs and signaling networks in non-small cell lung cancer: mechanistic insights into tumor pathogenesis12
New insights into the classification of the RAC1 P29S hotspot mutation in melanoma as an oncogene12
Oleuropein regulates ubiquitination-mediated Mcl-1 turnover and exhibits antitumor activity12
Epigenetically silenced apoptosis-associated tyrosine kinase (AATK) facilitates a decreased expression of Cyclin D1 and WEE1, phosphorylates TP53 and reduces cell proliferation in a kinase-dependent m12
Olfactomedin 4 produces dysplasia but suppresses metastasis of colon cancer12
GTF2E2 downregulated by miR-340-5p inhibits the malignant progression of glioblastoma12
m6A-modified circFOXK2 targets GLUT1 to accelerate oral squamous cell carcinoma aerobic glycolysis12
Redefining bioactive small molecules from microbial metabolites as revolutionary anticancer agents12
Therapeutic targeting of the tryptophan-kynurenine-aryl hydrocarbon receptor pathway with apigenin in MED12-mutant leiomyoma cells12
Suicide gene strategies applied in ovarian cancer studies12
Identification of a novel prognostic ADME-related signature associated with tumor immunity for aiding therapy in head and neck squamous cell carcinoma12
Editorial Expression of Concern: Herpes simplex virus thymidine kinase/ganciclovir–induced cell death is enhanced by co-expression of caspase-3 in ovarian carcinoma cells12
Retraction Note: circ_001504 promotes the development of renal cell carcinoma by sponging microRNA-149 to increase NUCB211
RUNX1A isoform is overexpressed in acute myeloid leukemia and is associated with FLT3 internal tandem duplications11
Atypical phosphatase DUSP11 inhibition promotes nc886 expression and potentiates gemcitabine-mediated cell death through NF-kB modulation11
FBXO22 promotes HCC angiogenesis and metastasis via RPS5/AKT/HIF-1α/VEGF-A signaling axis11
Abemaciclib impairs glioblastoma sphere formation by targeting the GSK3β-mediated transcriptional regulation of CD44 and TCF7L211
Methylstat sensitizes ovarian cancer cells to PARP-inhibition by targeting the histone demethylases JMJD1B/C11
Predicting colorectal cancer risk in FAP patients using patient-specific organoids11
Tumor stroma-derived ANGPTL2 potentiates immune checkpoint inhibitor efficacy11
Pals1 functions in redundancy with SMAP1 to inhibit Arf6 in order to prevent Rac1-dependent colorectal cancer cell migration and invasion11
CILP is a potential pan-cancer marker: combined silico study and in vitro analyses11
LncSNHGs: new targets in osteosarcoma11
Improving the cytotoxic response of tumor-infiltrating lymphocytes towards advanced stage ovarian cancer with an oncolytic adenovirus expressing a human vIL-2 cytokine11
The dual role of GPX4 in breast cancer: mechanisms of therapeutic resistance and potential for novel targeted therapies11
Cleavage and polyadenylation machinery as a novel targetable vulnerability for human cancer11
Has_circ_ASH1L acts as a sponge for miR-1254 to promote the malignant progression of cervical cancer by targeting CD3611
3-Bromopyruvate overcomes cetuximab resistance in human colorectal cancer cells by inducing autophagy-dependent ferroptosis11
The role of hsa_circ_0000520 in breast cancer progression: insights into the miR-542-3p/TMBIM6 regulatory axis11
IGH repertoire analysis at scale: deciphering the complexity of B cell infiltration and migration in esophageal squamous cell carcinoma10
METTL3 facilitates colorectal cancer growth through altering the abundance of intestinal Akkermansia muciniphila10
SEMA7A-mediated juxtacrine stimulation of IGFBP-3 upregulates IL-17RB at pancreatic cancer invasive front10
Silencing TRAIP suppresses cell proliferation and migration/invasion of triple negative breast cancer via RB-E2F signaling and EMT10
Unveiling mitochondrial and ribosomal gene deregulation and tumor microenvironment dynamics in acute myeloid leukemia10
DR1 activates histone gene expression to maintain pancreatic cancer cell survival through the ATAC complex10
SMARCB1-driven EGFR-GLI1 epigenetic alterations in lung cancer progression and therapy are differentially modulated by MEOX2 and GLI-110
Correction: PARD6A promotes lung adenocarcinoma cell proliferation and invasion through Serpina310
Blood-brain barrier breakdown in traumatic brain injury: current insights and future directions10
Single-nucleus and spatial transcriptomics analyses reveal interplay between evolutionary dynamics and energy metabolism in primary cardiac lymphoma10
CCR3 blockage elicits polyploidization associated with the signatures of epithelial-mesenchymal transition in carcinoma cell lines10
The TCR in CAR T cell therapy: use it or lose it?9
YAP 5-methylcytosine modification increases its mRNA stability and promotes the transcription of exosome secretion-related genes in lung adenocarcinoma9
Using RNA-seq for detecting MRD in multiple myeloma: high sensitivity and prognostic value9
Characterization of tertiary lymphoid structure identifies competitive binding of CD40 and STING with TRAF2 driving IRF4-mediated B cell activation in esophageal squamous cell carcinoma9
Targeting CREB-binding protein (CBP) abrogates colorectal cancer stemness through epigenetic regulation of C-MYC9
Bacterial nanoparticles as a potent and safe alternative to BCG for bladder cancer immunotherapy9
Exploring metabolic reprogramming in esophageal cancer: the role of key enzymes in glucose, amino acid, and nucleotide pathways and targeted therapies9
Role of MARK2 in the nervous system and cancer9
Cancer-associated fibroblast exosomes promote prostate cancer metastasis through miR-500a-3p/FBXW7/HSF1 axis under hypoxic microenvironment9
Cancer-derived exosomal miR-375 targets DIP2C and promotes osteoblastic metastasis and prostate cancer progression by regulating the Wnt signaling pathway9
Reductive cell death: the other side of the coin9
Retraction Note: Targeting KDM1B-dependent miR-215-AR-AGR2-axis promotes sensitivity to enzalutamide-resistant prostate cancer9
SIX3 function in cancer: progression and comprehensive analysis9
APOE deficiency triggers anti-tumour activity of macrophages in liver cancer9
Caveolin-1 knockout mitigates breast cancer metastasis to the lungs via integrin α3 dysregulation in 4T1-induced syngeneic breast cancer model9
Recent advances in the role of circRNA in cisplatin resistance in tumors9
Respective roles of Pik3ca mutations and cyproterone acetate impregnation in mouse meningioma tumorigenesis9
Hsa_circ_0013561 promotes epithelial-mesenchymal transition and tumor progression by regulating ANXA2 via miR-23b-3p in ovarian cancer9
Immuno-regulatory malignant B cells contribute to Chronic Lymphocytic Leukemia progression9
BAIAP2L2 promotes the malignancy of hepatocellular carcinoma via GABPB1-mediated reactive oxygen species imbalance9
ATPase copper transporting beta contributes to cisplatin resistance as a regulatory factor of extracellular vesicles in head and neck squamous cell carcinoma8
Research progress and application of single-cell sequencing in head and neck malignant tumors8
ITGA3 promotes pancreatic cancer progression through HIF1α- and c-Myc-driven glycolysis in a collagen I-dependent autocrine manner8
Targeting MTPN sensitizes pancreatic cancer of wild-type BRCA1/2 to Cisplatin-based chemotherapy8
Oncolytic HSV1 targets different growth phases of breast cancer leptomeningeal metastases8
UGT1A7 altered HER2-positive breast cancer response to trastuzumab by affecting epithelial-to-mesenchymal transition: A potential biomarker to identify patients resistant to trastuzumab treatment8
Novel long noncoding RNA LINC02820 augments TNF signaling pathway to remodel cytoskeleton and potentiate metastasis in esophageal squamous cell carcinoma8
Extracellular sialyltransferase st6gal1 in breast tumor cell growth and invasiveness8
The role of LncRNA-MANCR induced by HIF-1α drive the malignant progression of pancreatic cancer by targeting miRNA-494/SIRT1 signaling axis under hypoxic conditions8
Long non-coding RNA PRSS23-AS1 as ceRNA promotes breast cancer progression by regulating EMT via miR-3176 /YBX1 axis8
c-Myc-induced long noncoding RNA MIRE cooperates with hnRNPK to stabilize ELF2 mRNA and promotes clear cell renal cell carcinogenesis8
Pharmacological targeting of CBP/p300 drives a redox/autophagy axis leading to senescence-induced growth arrest in non-small cell lung cancer cells8
Therapeutic applications of local injection of hsa-miR-634 into canine spontaneous malignant melanoma tumors8
Correction to: Activation of CEACAM1 with an agonistic monoclonal antibody results in inhibition of melanoma cells8
Baicalein inhibits cell proliferation and induces apoptosis in brain glioma cells by downregulating the LGR4-EGFR pathway8
Tumor-promoting properties of karyopherin β1 in melanoma by stabilizing Ras-GTPase-activating protein SH3 domain-binding protein 17
Construction of the cancer cell continuum reveals hybrid EMT state driving lung adenocarcinoma aggression7
The splicing factor SF3B1 confers ferroptosis resistance and promotes lung adenocarcinoma progression via upregulation of SLC7A117
LMTK3 regulates breast cancer angiogenesis via a context-dependent mesenchymal-epithelial transition program7
Glioblastoma glycolytic signature predicts unfavorable prognosis, immunological heterogeneity, and ENO1 promotes microglia M2 polarization and cancer cell malignancy7
Small molecule-induced epigenomic reprogramming of APL blasts leading to antiviral-like response and c-MYC downregulation7
The function of brother of the regulator of imprinted sites in cancer development7
Histone 3 lysine 9 acetylation-specific reprogramming regulates esophageal squamous cell carcinoma progression and metastasis7
Transcription factor YY1 mediates self-renewal of glioblastoma stem cells through regulation of the SENP1/METTL3/MYC axis7
NF-κB-activated oncogene inhibition strategy for cancer gene therapy7
SPRTN is involved in hepatocellular carcinoma development through the ER stress response7
LINC00665 activating Wnt3a/β-catenin signaling by bond with YBX1 promotes gastric cancer proliferation and metastasis7
Phosphoglycerate mutase 1 promotes breast cancer progression through inducing immunosuppressive M2 macrophages7
Emerging roles of prohibitins in cancer: an update7
Identification of KIFC1 as a putative vulnerability in lung cancers with centrosome amplification7
Retraction Note: Nrf2 overexpression increases the resistance of acute myeloid leukemia to cytarabine by inhibiting replication factor C47
Disulfidptosis in cancer: from redox stress to therapeutic strategy7
The pleiotropic nature of NONO, a master regulator of essential biological pathways in cancers7
Carboxyl-terminal modulator protein facilitates tumor metastasis in triple-negative breast cancer7
The effects of intracellular and exosomal ncRNAs on cancer progression7
β3-adrenergic receptor on tumor-infiltrating lymphocytes sustains IFN-γ-dependent PD-L1 expression and impairs anti-tumor immunity in neuroblastoma7
Genetic trajectory and clonal evolution of multiple primary lung cancer with lymph node metastasis6
Patient-derived tumor models: a suitable tool for preclinical studies on esophageal cancer6
Overcoming biophysical barriers with innovative therapeutic delivery approaches6
High CAR intensity of expression confers enhanced antitumor effect against lymphoma without functional exhaustion6
Promoting the therapeutic potential of interleukin-7 (IL-7) by expression in viral vectors6
Correction: RUNX1A isoform is overexpressed in acute myeloid leukemia and is associated with FLT3 internal tandem duplications6
Multifaceted role of microRNA-301a in human cancer: from biomarker potential to therapeutic targeting6
Correction: The role of tumor-derived exosomal LncRNA in tumor metastasis6
HN1-mediated activation of lipogenesis through Akt-SREBP signaling promotes hepatocellular carcinoma cell proliferation and metastasis6
SATB1 regulates TXNIP inhibiting invasion and infiltration in T-cell acute lymphoblastic leukemia6
Heparanase interacting BCLAF1 to promote the development and drug resistance of ICC through the PERK/eIF2α pathway6
Divergent transcriptomic signatures from putative mesenchymal stimuli in glioblastoma cells6
TMTC1 promotes invasiveness of ovarian cancer cells through integrins β1 and β46
Perspective of smart nanocapsule swallowable laser-guided for integrated sensing and crispr-mediated cancer gene editing6
RAB3D/MDM2/β-catenin/c-MYC axis exacerbates the malignant behaviors of acute myeloid leukemia cells in vitro and in vivo6
CEACAM6 facilitates gastric cancer progression through upregulating SLC27A26
miR-451a was selectively sorted into exosomes and promoted the progression of esophageal squamous cell carcinoma through CAB396
Recent progress of CDK4/6 inhibitors’ current practice in breast cancer6
Therapeutic activity of retroviral replicating vector-mediated gene therapy in combination with anti-PD-1 antibody in a murine pancreatic cancer model6
Retraction Note: Cabozantinib induces PUMA-dependent apoptosis in colon cancer cells via AKT/GSK-3β/NF-κB signaling pathway6
Functional characterization of the PI3K/AKT/MTOR signaling pathway for targeted therapy in B-precursor acute lymphoblastic leukemia6
Chronic stress promotes non-small cell lung cancer (NSCLC) progression through circMBOAT2 upregulation mediated by CTCF6
Regulation of tumor metabolism by post translational modifications on metabolic enzymes6
ALKBH5-mediated m6A regulates the alternative splicing events of SRSF10 in ovarian cancer6
A multi-omics integrative approach unravels novel genes and pathways associated with senescence escape after targeted therapy in NRAS mutant melanoma5
The antitumor peptide M1-20 induced the degradation of CDK1 through CUL4-DDB1-DCAF1-involved ubiquitination5
A truncated and catalytically inactive isoform of KDM5B histone demethylase accumulates in breast cancer cells and regulates H3K4 tri-methylation and gene expression5
Inhibition of orthotopic castration-resistant prostate cancer growth and metastasis in mice by JC VLPs carrying a suicide gene driven by the PSA promoter5
Deciphering the role of post-translational modifications in fanconi anemia proteins and their influence on tumorigenesis5
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