Cancer Gene Therapy

Papers
(The median citation count of Cancer Gene Therapy is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)
ArticleCitations
Reducing the risks of nuclear war—the role of health professionals137
Use of CRISPR-based screens to identify mechanisms of chemotherapy resistance134
Defining treatment-resistant brain cancer: Genetic screening to identify oncogene-driven immunomodulation and therapy resistance125
Correction to: Identification of a five genes prognosis signature for triple-negative breast cancer using multi-omics methods and bioinformatics analysis119
Platelet activation: a barrier to effective antitumor immunity104
ADAM12 expression is upregulated in cancer cells upon radiation and constitutes a prognostic factor in rectal cancer patients following radiotherapy79
Characteristics and developmental trajectory of clinical trials focused on tumor-infiltrating lymphocytes for cancer treatment77
Small extracellular vesicle TGF-β in cancer progression and immune evasion70
Lysine-40 succinylation of TAGLN2 induces glioma angiogenesis and tumor growth through regulating TMSB4X66
Circ-GSK3B up-regulates GSK3B to suppress the progression of lung adenocarcinoma65
P38 kinase in gastrointestinal cancers56
Application of CAR-T therapy in solid tumors: current opportunities and challenges52
Ending nuclear weapons, before they end us48
Unveiling the role of the extracellular matrix in the osteosarcoma tumor microenvironment through integrated transcriptomics and experimental validation46
Role of non-coding RNAs in neuroblastoma45
Pan-cancer oncogenic properties and therapeutic potential of SF3B445
Long noncoding RNA EPCART regulates translation through PI3K/AKT/mTOR pathway and PDCD4 in prostate cancer42
Self-replicating messenger RNA based cancer immunotherapy40
NRAV promotes HCC stemness via the m6A-regulated let-7c-5p/LIN28B axis38
CircPKN2 promotes ferroptosis in bladder cancer by promoting the ubiquitination of Stearoyl-CoA Desaturase 137
TNFRSF19 promotes endoplasmic reticulum stress-induced paraptosis via the activation of the MAPK pathway in triple-negative breast cancer cells36
Targeting TLK2 inhibits the progression of gastric cancer by reprogramming amino acid metabolism through the mTOR/ASNS axis35
PDPN contributes to constructing immunosuppressive microenvironment in IDH wildtype glioma34
Viral vectors and extracellular vesicles: innate delivery systems utilized in CRISPR/Cas-mediated cancer therapy33
Real-world outcomes of Adjuvant De Gramont versus Xelox chemotherapy in reSected gasTric cancER: a propensity score-matched analysis (ASTER study)31
LncRNA CALML3-AS1 modulated by m6A modification induces BTNL9 methylation to drive non-small-cell lung cancer progression31
circXRCC5 foster gastric cancer growth and metastasis by the HNRNPC/circXRCC5/miR-655-3p/RREB1/UBA2 positive feedback loop31
Bacillus Calmette-Guerin induces CD8+ T cell infiltration and suppresses tumor progression in microsatellite stable colorectal cancer by downregulating ARID1A30
CDK5RAP3 acts as a tumour suppressor in gastric cancer through the infiltration and polarization of tumour-associated macrophages29
Correction to: Lycium barbarum glycopeptide targets PER2 to inhibit lipogenesis in glioblastoma by downregulating SREBP1c29
BCL-xL dependency in chromophobe renal cell carcinoma28
TRPM8 promotes hepatocellular carcinoma progression by inducing SNORA55 mediated nuclear-mitochondrial communication28
Single-cell atlas reveals the immunosuppressive microenvironment and Treg cells landscapes in recurrent Glioblastoma28
Targeted inactivation of EWSR1 : : FLI1 gene in Ewing sarcoma via CRISPR/Cas9 driven by an Ewing-specific GGAA promoter27
WTAP stabilized by USP7 contributes to enzalutamide resistance in prostate cancer via mediating AKT m6A-modification26
Identification of HDAC4 as a potential therapeutic target and prognostic biomarker for ZFTA-fused ependymomas26
The target atlas for antibody-drug conjugates across solid cancers26
Exploring RNA biology in pseudomyxoma peritonei uncovers splicing dysregulation as a novel, targetable molecular vulnerability26
NRF2-SOX4 complex regulates PSPH in hepatocellular carcinoma and modulates M2 macrophage differentiation26
A conditionally replicative adenovirus vector containing the synNotch receptor gene for the treatment of muscle-invasive bladder cancer25
Suppression of FOXO1 activity by SIRT1-mediated deacetylation weakening the intratumoral androgen autocrine function in glioblastoma25
LOXL1-AS1 inhibits JAK2 ubiquitination and promotes cholangiocarcinoma progression through JAK2/STAT3 signaling24
Manipulating the tumour immune microenvironment by N6-methyladenosine RNA modification24
SMAD4-armed oncolytic adenovirus therapy potentiates the chemotherapy effects in NSCLC through suppression of the Wnt/β-catenin pathway23
EZH1/2 as targets for cancer therapy23
Retraction Note: Overexpressed transient receptor potential vanilloid 1 (TRPV1) in lung adenocarcinoma harbours a new opportunity for therapeutic targeting22
CAR T cells as micropharmacies against solid cancers: Combining effector T-cell mediated cell death with vascular targeting in a one-step engineering process22
The FOSB-IGFBP5-IGF-1 axis: a novel regulatory pathway that suppresses prostate cancer growth22
Editorial Expression of Concern: p73β-expressing recombinant adenovirus: a potential anticancer agent21
Editorial Expression of Concern: E1A-induced apoptosis does not prevent replication of adenoviruses with deletion of E1b in majority of infected cancer cells21
BETA prime: a first-in-man phase 1 study of AdAPT-001, an armed oncolytic adenovirus for solid tumors21
AAV-mediated combination gene therapy of inducible Caspase 9 and miR-199a-5p is therapeutic in hepatocellular carcinoma20
Tumor-derived ARHGAP35 mutations enhance the Gα13-Rho signaling axis in human endometrial cancer20
Landscape and functional impact of variants of unknown significance of immune response genes in human cancer20
m6A-modified circABCC4 promotes stemness and metastasis of prostate cancer by recruiting IGF2BP2 to increase stability of CCAR120
Circular RNA RHBDD1 regulates tumorigenicity and ferroptosis in colorectal cancer by mediating the ELAVL1/SCD mRNA interaction20
Nogo-B receptor increases glycolysis and the paclitaxel resistance of estrogen receptor-positive breast cancer via the HIF-1α-dependent pathway20
Biodistribution and toxicity evaluation of oncolytic adenovirus Adf35(OGN) in Syrian hamster and mouse20
ECT2 promotes malignant phenotypes through the activation of the AKT/mTOR pathway and cisplatin resistance in cervical cancer19
Reversible downregulation of MYC in a spheroid model of metastatic epithelial ovarian cancer19
Intraperitoneal administration of adeno-associated virus encoding microRNA-29b for the treatment of peritoneal metastasis19
HIF-1α/IL-8 axis in hypoxic macrophages promotes esophageal cancer progression by enhancing PD-L1 expression19
A guardian turned rogue: TP53 promoter translocations rewire stress responses to oncogenic effectors in osteosarcoma19
Arsenic trioxide and p97 inhibitor synergize against acute myeloid leukemia by targeting nascent polypeptides and activating the ZAKα–JNK pathway19
IER3: exploring its dual function as an oncogene and tumor suppressor19
Hidden patterns of gene expression provide prognostic insight for colorectal cancer19
Chimeric Ad5/35 oncolytic adenovirus overcome preexisting neutralizing antibodies and enhance tumor targeting efficiency18
Structural regulation of PLK1 activity: implications for cell cycle function and drug discovery18
Glimmers of hope for targeting oncogenic KRAS-G12D18
METTL3 promotes the malignancy of non-small cell lung cancer by N6-methyladenosine modifying SFRP218
p53-regulated lncRNAs in cancers: from proliferation and metastasis to therapy18
Knock-out of 5-lipoxygenase in overexpressing tumor cells—consequences on gene expression and cellular function18
Pleiotropic mechanisms of cancer-associated fibroblast-mediated resistance in hepatocellular carcinoma: emerging therapeutic vulnerabilities and targeting strategies18
Extracellular vesicles released by glioma cells are decorated by Annexin A2 allowing for cellular uptake via heparan sulfate18
Therapeutic potential of synthetic microRNA mimics based on the miR-15/107 consensus sequence17
Proteomic profiling reveals ACSS2 facilitating metabolic support in acute myeloid leukemia17
Transactivation of Met signaling by oncogenic Gnaq drives the evolution of melanoma in Hgf-Cdk4 mice17
Blocking tri-methylguanosine synthase 1 (TGS1) stops anchorage-independent growth of canine sarcomas17
CRISPR-Cas gene knockouts to optimize engineered T cells for cancer immunotherapy17
WWOX binds MERIT40 and modulates its function in homologous recombination, implications in breast cancer17
CASC4/GOLM2 drives high grade serous carcinoma anoikis resistance through the recycling of EGFR16
Effective delivery of genome editor to cervical cancer targeting Mcl1 for cancer therapy16
FOXM1 promotes neurofibromatosis type 1-associated malignant peripheral nerve sheath tumor progression in a NUF2-dependent manner16
SOCS3 inhibiting JAK-STAT pathway enhances oncolytic adenovirus efficacy by potentiating viral replication and T-cell activation16
TFF3 sensitizes cervical carcinoma cells to cisplatin toxicity by binding to IGF2R16
Utilizing nullomers in cell-free RNA for early cancer detection16
SPP1+ TAM subpopulations in tumor microenvironment promote intravasation and metastasis of head and neck squamous cell carcinoma16
MBD1 protects replication fork stability by recruiting PARP1 and controlling transcription-replication conflicts16
GPR107: A key driver of breast cancer invasion and metastasis through collagen IV modulation15
Global characterization of megakaryocytes in bone marrow, peripheral blood, and cord blood by single-cell RNA sequencing15
Integrating system biology and intratumor gene therapy by trans-complementing the appropriate co-stimulatory molecule as payload in oncolytic herpes virus15
Correction: Arsenic trioxide and p97 inhibitor synergize against acute myeloid leukemia by targeting nascent polypeptides and activating the ZAKα–JNK pathway15
Detection of (pre)cancerous colorectal lesions in Lynch syndrome patients by microsatellite instability liquid biopsy15
Correction to: Single-cell RNA sequencing reveals changes in glioma-associated macrophage polarization and cellular states of malignant gliomas with high AQP4 expression15
Gastrointestinal infections and gastrointestinal haemorrhage are underestimated but serious adverse events in chimeric antigen receptor T-cell recipients: A real-world study14
GLIPR1 promotes proliferation, metastasis and 5-fluorouracil resistance in hepatocellular carcinoma by activating the PI3K/PDK1/ROCK1 pathway14
The long-term effectiveness and mechanism of oncolytic virotherapy combined with anti-PD-L1 antibody in colorectal cancer patient14
Long noncoding RNA LINC00173 induces radioresistance in nasopharyngeal carcinoma via inhibiting CHK2/P53 pathway14
Correction to: Nogo-B receptor increases glycolysis and the paclitaxel resistance of estrogen receptor-positive breast cancer via the HIF-1α-dependent pathway14
RevCAR-expressing immune effector cells for targeting of Fn14-positive glioblastoma14
An alternative fully human anti-BCMA CAR-T shows response for relapsed or refractory multiple myeloma with anti-BCMA CAR-T exposures previously14
HPV status represents dominant trait driving delineation of survival-associated gene co-expression networks in head and neck cancer14
STAT5a and SH2B3 novel mutations display malignancy roles in a triple-negative primary myelofibrosis patient14
TSPAN1 inhibits metastasis of nasopharyngeal carcinoma via suppressing NF-kB signaling14
MALNC: a new mutant NPM1/IDH2R140 and PML-RARA-associated lncRNA with impact on AML cell proliferation, maturation and drug response14
Activation of CEACAM1 with an agonistic monoclonal antibody results in inhibition of melanoma cells13
Microbiota in tumors: new factor influencing cancer development13
Identification of lineage-specific epigenetic regulators FOXA1 and GRHL2 through chromatin accessibility profiling in breast cancer cell lines13
Clathrin-associated SCYL2 contributes to the activation of PI3K/AKT signaling and tumorigenesis through PTEN phosphorylation in adult T-cell leukemia/lymphoma13
SPARC family proteins: matricellular modulators of cancer progression and therapeutic resistance13
Integration of humanized ROBO1 CAR in PD-1 locus in natural killer cells delivers synergistic tumor-killing effect against non-small cell lung cancer13
Regional infusion of a class C TLR9 agonist enhances liver tumor microenvironment reprogramming and MDSC reduction to improve responsiveness to systemic checkpoint inhibition13
A novel intranasal peptide vaccine inhibits non-small cell lung cancer with KRAS mutation13
Cell-intrinsic platinum response and associated genetic and gene expression signatures in ovarian cancer13
Lipid-related FABP5 activation of tumor-associated monocytes fosters immune privilege via PD-L1 expression on Treg cells in hepatocellular carcinoma13
Clonal dynamics limits detection of selection in tumour xenograft CRISPR/Cas9 screens13
Engineered L-asparaginase variants with enhanced therapeutic properties to improve treatment of childhood acute lymphatic leukemia13
Retraction Note: microRNA-133a exerts tumor suppressive role in oral squamous cell carcinoma through the Notch signaling pathway via downregulation of CTBP212
New insights into the classification of the RAC1 P29S hotspot mutation in melanoma as an oncogene12
Correction: Pan-cancer oncogenic properties and therapeutic potential of SF3B412
Olfactomedin 4 produces dysplasia but suppresses metastasis of colon cancer12
GAS5 attenuates the malignant progression of glioma stem-like cells by promoting E-cadherin12
m6A-modified circFOXK2 targets GLUT1 to accelerate oral squamous cell carcinoma aerobic glycolysis12
Activating NRF2E79Q mutation alters the differentiation of human non-small cell lung cancer12
Editorial Expression of Concern: Herpes simplex virus thymidine kinase/ganciclovir–induced cell death is enhanced by co-expression of caspase-3 in ovarian carcinoma cells12
Redefining bioactive small molecules from microbial metabolites as revolutionary anticancer agents12
Correction: Hedyotis diffusae Herba-Andrographis Herba inhibits the cellular proliferation of nasopharyngeal carcinoma and triggers DNA damage through activation of p53 and p2112
Anti-angiogenesis and anti-immunosuppression gene therapy through targeting COUP-TFII in an in situ glioblastoma mouse model12
Therapeutic targeting of the tryptophan-kynurenine-aryl hydrocarbon receptor pathway with apigenin in MED12-mutant leiomyoma cells12
Anti-leukemia effects of omipalisib in acute myeloid leukemia: inhibition of PI3K/AKT/mTOR signaling and suppression of mitochondrial biogenesis12
Epigenetically silenced apoptosis-associated tyrosine kinase (AATK) facilitates a decreased expression of Cyclin D1 and WEE1, phosphorylates TP53 and reduces cell proliferation in a kinase-dependent m12
Estrogen receptor status heterogeneity in breast cancer tumor: role in response to endocrine treatment12
Tumor stroma-derived ANGPTL2 potentiates immune checkpoint inhibitor efficacy11
Oleuropein regulates ubiquitination-mediated Mcl-1 turnover and exhibits antitumor activity11
Cleavage and polyadenylation machinery as a novel targetable vulnerability for human cancer11
The dual role of GPX4 in breast cancer: mechanisms of therapeutic resistance and potential for novel targeted therapies11
Methylstat sensitizes ovarian cancer cells to PARP-inhibition by targeting the histone demethylases JMJD1B/C11
Suicide gene strategies applied in ovarian cancer studies11
Identification of a novel prognostic ADME-related signature associated with tumor immunity for aiding therapy in head and neck squamous cell carcinoma11
Pals1 functions in redundancy with SMAP1 to inhibit Arf6 in order to prevent Rac1-dependent colorectal cancer cell migration and invasion11
Long non-coding RNAs and signaling networks in non-small cell lung cancer: mechanistic insights into tumor pathogenesis11
Atypical phosphatase DUSP11 inhibition promotes nc886 expression and potentiates gemcitabine-mediated cell death through NF-kB modulation11
Integrated multidimensional bioinformatics analysis of the molecular mechanisms of ulcerative colitis-associated colorectal cancer and MMP1 as a potential therapeutic target11
RUNX1A isoform is overexpressed in acute myeloid leukemia and is associated with FLT3 internal tandem duplications11
GTF2E2 downregulated by miR-340-5p inhibits the malignant progression of glioblastoma11
Has_circ_ASH1L acts as a sponge for miR-1254 to promote the malignant progression of cervical cancer by targeting CD3611
Retraction Note: circ_001504 promotes the development of renal cell carcinoma by sponging microRNA-149 to increase NUCB210
The role of hsa_circ_0000520 in breast cancer progression: insights into the miR-542-3p/TMBIM6 regulatory axis10
IGH repertoire analysis at scale: deciphering the complexity of B cell infiltration and migration in esophageal squamous cell carcinoma10
FBXO22 promotes HCC angiogenesis and metastasis via RPS5/AKT/HIF-1α/VEGF-A signaling axis10
Improving the cytotoxic response of tumor-infiltrating lymphocytes towards advanced stage ovarian cancer with an oncolytic adenovirus expressing a human vIL-2 cytokine10
LncSNHGs: new targets in osteosarcoma10
Blood-brain barrier breakdown in traumatic brain injury: current insights and future directions10
SEMA7A-mediated juxtacrine stimulation of IGFBP-3 upregulates IL-17RB at pancreatic cancer invasive front10
3-Bromopyruvate overcomes cetuximab resistance in human colorectal cancer cells by inducing autophagy-dependent ferroptosis10
Predicting colorectal cancer risk in FAP patients using patient-specific organoids10
Abemaciclib impairs glioblastoma sphere formation by targeting the GSK3β-mediated transcriptional regulation of CD44 and TCF7L210
CILP is a potential pan-cancer marker: combined silico study and in vitro analyses10
Unveiling mitochondrial and ribosomal gene deregulation and tumor microenvironment dynamics in acute myeloid leukemia10
Hsa_circ_0013561 promotes epithelial-mesenchymal transition and tumor progression by regulating ANXA2 via miR-23b-3p in ovarian cancer9
Caveolin-1 knockout mitigates breast cancer metastasis to the lungs via integrin α3 dysregulation in 4T1-induced syngeneic breast cancer model9
Retraction Note: Targeting KDM1B-dependent miR-215-AR-AGR2-axis promotes sensitivity to enzalutamide-resistant prostate cancer9
DR1 activates histone gene expression to maintain pancreatic cancer cell survival through the ATAC complex9
Respective roles of Pik3ca mutations and cyproterone acetate impregnation in mouse meningioma tumorigenesis9
Targeting MTPN sensitizes pancreatic cancer of wild-type BRCA1/2 to Cisplatin-based chemotherapy9
Bacterial nanoparticles as a potent and safe alternative to BCG for bladder cancer immunotherapy9
Reductive cell death: the other side of the coin9
CCR3 blockage elicits polyploidization associated with the signatures of epithelial-mesenchymal transition in carcinoma cell lines9
METTL3 facilitates colorectal cancer growth through altering the abundance of intestinal Akkermansia muciniphila9
Targeting CREB-binding protein (CBP) abrogates colorectal cancer stemness through epigenetic regulation of C-MYC9
Silencing TRAIP suppresses cell proliferation and migration/invasion of triple negative breast cancer via RB-E2F signaling and EMT9
Immuno-regulatory malignant B cells contribute to Chronic Lymphocytic Leukemia progression9
BAIAP2L2 promotes the malignancy of hepatocellular carcinoma via GABPB1-mediated reactive oxygen species imbalance9
Correction: PARD6A promotes lung adenocarcinoma cell proliferation and invasion through Serpina39
Characterization of tertiary lymphoid structure identifies competitive binding of CD40 and STING with TRAF2 driving IRF4-mediated B cell activation in esophageal squamous cell carcinoma9
Cancer-derived exosomal miR-375 targets DIP2C and promotes osteoblastic metastasis and prostate cancer progression by regulating the Wnt signaling pathway9
SMARCB1-driven EGFR-GLI1 epigenetic alterations in lung cancer progression and therapy are differentially modulated by MEOX2 and GLI-19
Using RNA-seq for detecting MRD in multiple myeloma: high sensitivity and prognostic value9
SIX3 function in cancer: progression and comprehensive analysis9
ITGA3 promotes pancreatic cancer progression through HIF1α- and c-Myc-driven glycolysis in a collagen I-dependent autocrine manner8
The TCR in CAR T cell therapy: use it or lose it?8
Therapeutic applications of local injection of hsa-miR-634 into canine spontaneous malignant melanoma tumors8
Long non-coding RNA PRSS23-AS1 as ceRNA promotes breast cancer progression by regulating EMT via miR-3176 /YBX1 axis8
Oncolytic HSV1 targets different growth phases of breast cancer leptomeningeal metastases8
Disulfidptosis in cancer: from redox stress to therapeutic strategy8
The role of LncRNA-MANCR induced by HIF-1α drive the malignant progression of pancreatic cancer by targeting miRNA-494/SIRT1 signaling axis under hypoxic conditions8
Exploring metabolic reprogramming in esophageal cancer: the role of key enzymes in glucose, amino acid, and nucleotide pathways and targeted therapies8
YAP 5-methylcytosine modification increases its mRNA stability and promotes the transcription of exosome secretion-related genes in lung adenocarcinoma8
Cancer-associated fibroblast exosomes promote prostate cancer metastasis through miR-500a-3p/FBXW7/HSF1 axis under hypoxic microenvironment8
Extracellular sialyltransferase st6gal1 in breast tumor cell growth and invasiveness8
Novel long noncoding RNA LINC02820 augments TNF signaling pathway to remodel cytoskeleton and potentiate metastasis in esophageal squamous cell carcinoma8
Pharmacological targeting of CBP/p300 drives a redox/autophagy axis leading to senescence-induced growth arrest in non-small cell lung cancer cells8
The splicing factor SF3B1 confers ferroptosis resistance and promotes lung adenocarcinoma progression via upregulation of SLC7A118
APOE deficiency triggers anti-tumour activity of macrophages in liver cancer8
Recent advances in the role of circRNA in cisplatin resistance in tumors8
Role of MARK2 in the nervous system and cancer8
LMTK3 regulates breast cancer angiogenesis via a context-dependent mesenchymal-epithelial transition program8
Identification of KIFC1 as a putative vulnerability in lung cancers with centrosome amplification8
NF-κB-activated oncogene inhibition strategy for cancer gene therapy8
c-Myc-induced long noncoding RNA MIRE cooperates with hnRNPK to stabilize ELF2 mRNA and promotes clear cell renal cell carcinogenesis7
Construction of the cancer cell continuum reveals hybrid EMT state driving lung adenocarcinoma aggression7
SPRTN is involved in hepatocellular carcinoma development through the ER stress response7
Retraction Note: Nrf2 overexpression increases the resistance of acute myeloid leukemia to cytarabine by inhibiting replication factor C47
Transcription factor YY1 mediates self-renewal of glioblastoma stem cells through regulation of the SENP1/METTL3/MYC axis7
Baicalein inhibits cell proliferation and induces apoptosis in brain glioma cells by downregulating the LGR4-EGFR pathway7
ATPase copper transporting beta contributes to cisplatin resistance as a regulatory factor of extracellular vesicles in head and neck squamous cell carcinoma7
Histone 3 lysine 9 acetylation-specific reprogramming regulates esophageal squamous cell carcinoma progression and metastasis7
β3-adrenergic receptor on tumor-infiltrating lymphocytes sustains IFN-γ-dependent PD-L1 expression and impairs anti-tumor immunity in neuroblastoma7
The pleiotropic nature of NONO, a master regulator of essential biological pathways in cancers7
Research progress and application of single-cell sequencing in head and neck malignant tumors7
UGT1A7 altered HER2-positive breast cancer response to trastuzumab by affecting epithelial-to-mesenchymal transition: A potential biomarker to identify patients resistant to trastuzumab treatment7
Tumor-promoting properties of karyopherin β1 in melanoma by stabilizing Ras-GTPase-activating protein SH3 domain-binding protein 17
Glioblastoma glycolytic signature predicts unfavorable prognosis, immunological heterogeneity, and ENO1 promotes microglia M2 polarization and cancer cell malignancy7
LINC00665 activating Wnt3a/β-catenin signaling by bond with YBX1 promotes gastric cancer proliferation and metastasis7
Emerging roles of prohibitins in cancer: an update7
Correction to: Activation of CEACAM1 with an agonistic monoclonal antibody results in inhibition of melanoma cells7
Overcoming biophysical barriers with innovative therapeutic delivery approaches6
Therapeutic activity of retroviral replicating vector-mediated gene therapy in combination with anti-PD-1 antibody in a murine pancreatic cancer model6
Retraction Note: Cabozantinib induces PUMA-dependent apoptosis in colon cancer cells via AKT/GSK-3β/NF-κB signaling pathway6
Heparanase interacting BCLAF1 to promote the development and drug resistance of ICC through the PERK/eIF2α pathway6
Promoting the therapeutic potential of interleukin-7 (IL-7) by expression in viral vectors6
Rapamycin rescues APC-mutated colon organoid differentiation6
Recent progress of CDK4/6 inhibitors’ current practice in breast cancer6
Functional characterization of the PI3K/AKT/MTOR signaling pathway for targeted therapy in B-precursor acute lymphoblastic leukemia6
SATB1 regulates TXNIP inhibiting invasion and infiltration in T-cell acute lymphoblastic leukemia6
Patient-derived tumor models: a suitable tool for preclinical studies on esophageal cancer6
Phosphoglycerate mutase 1 promotes breast cancer progression through inducing immunosuppressive M2 macrophages6
Small molecule-induced epigenomic reprogramming of APL blasts leading to antiviral-like response and c-MYC downregulation6
The function of brother of the regulator of imprinted sites in cancer development6
TMTC1 promotes invasiveness of ovarian cancer cells through integrins β1 and β46
Correction: RUNX1A isoform is overexpressed in acute myeloid leukemia and is associated with FLT3 internal tandem duplications6
miR-451a was selectively sorted into exosomes and promoted the progression of esophageal squamous cell carcinoma through CAB396
High CAR intensity of expression confers enhanced antitumor effect against lymphoma without functional exhaustion6
The effects of intracellular and exosomal ncRNAs on cancer progression6
Carboxyl-terminal modulator protein facilitates tumor metastasis in triple-negative breast cancer6
HN1-mediated activation of lipogenesis through Akt-SREBP signaling promotes hepatocellular carcinoma cell proliferation and metastasis6
Genetic trajectory and clonal evolution of multiple primary lung cancer with lymph node metastasis6
Novel treatment paradigms for metastatic uveal melanoma6
CEACAM6 facilitates gastric cancer progression through upregulating SLC27A26
Divergent transcriptomic signatures from putative mesenchymal stimuli in glioblastoma cells6
Targeting SOD1 via RNAi with PEGylated graphene oxide nanoparticles in platinum-resistant ovarian cancer5
Retraction Note: BET inhibitor I-BET151 sensitizes GBM cells to temozolomide via PUMA induction5
Correction: SEMA7A-mediated juxtacrine stimulation of IGFBP-3 upregulates IL-17RB at pancreatic cancer invasive front5
Inhibition of orthotopic castration-resistant prostate cancer growth and metastasis in mice by JC VLPs carrying a suicide gene driven by the PSA promoter5
Deciphering the role of post-translational modifications in fanconi anemia proteins and their influence on tumorigenesis5
A multi-omics integrative approach unravels novel genes and pathways associated with senescence escape after targeted therapy in NRAS mutant melanoma5
Correction: H3.3-G34W in giant cell tumor of bone functionally aligns with the exon choice repressor hnRNPA1L25
Features of metabolism associated molecular patterns in pancreatic ductal adenocarcinoma5
Understanding, diagnosing, and treating pancreatic cancer from the perspective of telomeres and telomerase5
Lnc-ABCA12-8 confers acquired resistance to gefitinib in non-small cell lung cancer by regulating the alternative splicing of fibronectin 1 in the IIICS region5
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