Cancer Gene Therapy

Papers
(The median citation count of Cancer Gene Therapy is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)
ArticleCitations
Reducing the risks of nuclear war—the role of health professionals158
Platelet activation: a barrier to effective antitumor immunity153
ADAM12 expression is upregulated in cancer cells upon radiation and constitutes a prognostic factor in rectal cancer patients following radiotherapy149
Characteristics and developmental trajectory of clinical trials focused on tumor-infiltrating lymphocytes for cancer treatment139
P38 kinase in gastrointestinal cancers88
Application of CAR-T therapy in solid tumors: current opportunities and challenges84
Defining treatment-resistant brain cancer: Genetic screening to identify oncogene-driven immunomodulation and therapy resistance74
Use of CRISPR-based screens to identify mechanisms of chemotherapy resistance71
VPS37A loss creates CASP8-dependent vulnerability via the MAP3K7–NF-κB–CFLAR axis70
Lysine-40 succinylation of TAGLN2 induces glioma angiogenesis and tumor growth through regulating TMSB4X58
Small extracellular vesicle TGF-β in cancer progression and immune evasion53
Ending nuclear weapons, before they end us50
Role of non-coding RNAs in neuroblastoma48
Pan-cancer oncogenic properties and therapeutic potential of SF3B443
Long noncoding RNA EPCART regulates translation through PI3K/AKT/mTOR pathway and PDCD4 in prostate cancer41
CircPKN2 promotes ferroptosis in bladder cancer by promoting the ubiquitination of Stearoyl-CoA Desaturase 139
Targeting TLK2 inhibits the progression of gastric cancer by reprogramming amino acid metabolism through the mTOR/ASNS axis39
TNFRSF19 promotes endoplasmic reticulum stress-induced paraptosis via the activation of the MAPK pathway in triple-negative breast cancer cells39
Self-replicating messenger RNA based cancer immunotherapy39
Unveiling the role of the extracellular matrix in the osteosarcoma tumor microenvironment through integrated transcriptomics and experimental validation38
PDPN contributes to constructing immunosuppressive microenvironment in IDH wildtype glioma36
Viral vectors and extracellular vesicles: innate delivery systems utilized in CRISPR/Cas-mediated cancer therapy34
NRAV promotes HCC stemness via the m6A-regulated let-7c-5p/LIN28B axis33
BCL-xL dependency in chromophobe renal cell carcinoma32
Single-cell atlas reveals the immunosuppressive microenvironment and Treg cells landscapes in recurrent Glioblastoma32
WTAP stabilized by USP7 contributes to enzalutamide resistance in prostate cancer via mediating AKT m6A-modification31
Real-world outcomes of Adjuvant De Gramont versus Xelox chemotherapy in reSected gasTric cancER: a propensity score-matched analysis (ASTER study)31
Bacillus Calmette-Guerin induces CD8+ T cell infiltration and suppresses tumor progression in microsatellite stable colorectal cancer by downregulating ARID1A30
Exploring RNA biology in pseudomyxoma peritonei uncovers splicing dysregulation as a novel, targetable molecular vulnerability30
Correction to: Lycium barbarum glycopeptide targets PER2 to inhibit lipogenesis in glioblastoma by downregulating SREBP1c30
TRPM8 promotes hepatocellular carcinoma progression by inducing SNORA55 mediated nuclear-mitochondrial communication29
The target atlas for antibody-drug conjugates across solid cancers29
Targeted inactivation of EWSR1 : : FLI1 gene in Ewing sarcoma via CRISPR/Cas9 driven by an Ewing-specific GGAA promoter29
CDK5RAP3 acts as a tumour suppressor in gastric cancer through the infiltration and polarization of tumour-associated macrophages27
SMAD4-armed oncolytic adenovirus therapy potentiates the chemotherapy effects in NSCLC through suppression of the Wnt/β-catenin pathway26
LncRNA CALML3-AS1 modulated by m6A modification induces BTNL9 methylation to drive non-small-cell lung cancer progression26
Identification of HDAC4 as a potential therapeutic target and prognostic biomarker for ZFTA-fused ependymomas26
LOXL1-AS1 inhibits JAK2 ubiquitination and promotes cholangiocarcinoma progression through JAK2/STAT3 signaling26
Editorial Expression of Concern: E1A-induced apoptosis does not prevent replication of adenoviruses with deletion of E1b in majority of infected cancer cells25
A conditionally replicative adenovirus vector containing the synNotch receptor gene for the treatment of muscle-invasive bladder cancer25
Editorial Expression of Concern: p73β-expressing recombinant adenovirus: a potential anticancer agent25
The FOSB-IGFBP5-IGF-1 axis: a novel regulatory pathway that suppresses prostate cancer growth24
EZH1/2 as targets for cancer therapy24
Retraction Note: Overexpressed transient receptor potential vanilloid 1 (TRPV1) in lung adenocarcinoma harbours a new opportunity for therapeutic targeting24
m6A-modified circABCC4 promotes stemness and metastasis of prostate cancer by recruiting IGF2BP2 to increase stability of CCAR123
AAV-mediated combination gene therapy of inducible Caspase 9 and miR-199a-5p is therapeutic in hepatocellular carcinoma23
Nogo-B receptor increases glycolysis and the paclitaxel resistance of estrogen receptor-positive breast cancer via the HIF-1α-dependent pathway23
Manipulating the tumour immune microenvironment by N6-methyladenosine RNA modification22
Suppression of FOXO1 activity by SIRT1-mediated deacetylation weakening the intratumoral androgen autocrine function in glioblastoma22
Landscape and functional impact of variants of unknown significance of immune response genes in human cancer22
NRF2-SOX4 complex regulates PSPH in hepatocellular carcinoma and modulates M2 macrophage differentiation22
BETA prime: a first-in-man phase 1 study of AdAPT-001, an armed oncolytic adenovirus for solid tumors22
Circular RNA RHBDD1 regulates tumorigenicity and ferroptosis in colorectal cancer by mediating the ELAVL1/SCD mRNA interaction22
Reversible downregulation of MYC in a spheroid model of metastatic epithelial ovarian cancer21
Biodistribution and toxicity evaluation of oncolytic adenovirus Adf35(OGN) in Syrian hamster and mouse21
Hidden patterns of gene expression provide prognostic insight for colorectal cancer21
Tumor-derived ARHGAP35 mutations enhance the Gα13-Rho signaling axis in human endometrial cancer21
METTL3 promotes the malignancy of non-small cell lung cancer by N6-methyladenosine modifying SFRP221
A guardian turned rogue: TP53 promoter translocations rewire stress responses to oncogenic effectors in osteosarcoma21
CAR T cells as micropharmacies against solid cancers: Combining effector T-cell mediated cell death with vascular targeting in a one-step engineering process21
Intraperitoneal administration of adeno-associated virus encoding microRNA-29b for the treatment of peritoneal metastasis21
ECT2 promotes malignant phenotypes through the activation of the AKT/mTOR pathway and cisplatin resistance in cervical cancer20
Pleiotropic mechanisms of cancer-associated fibroblast-mediated resistance in hepatocellular carcinoma: emerging therapeutic vulnerabilities and targeting strategies20
Arsenic trioxide and p97 inhibitor synergize against acute myeloid leukemia by targeting nascent polypeptides and activating the ZAKα–JNK pathway20
p53-regulated lncRNAs in cancers: from proliferation and metastasis to therapy20
Chimeric Ad5/35 oncolytic adenovirus overcome preexisting neutralizing antibodies and enhance tumor targeting efficiency20
PYGO2 is overexpressed in multiple myeloma patients with 1q21 amplification, driving plasma cell proliferation and cell cycle progression19
Glimmers of hope for targeting oncogenic KRAS-G12D19
HIF-1α/IL-8 axis in hypoxic macrophages promotes esophageal cancer progression by enhancing PD-L1 expression19
Extracellular vesicles released by glioma cells are decorated by Annexin A2 allowing for cellular uptake via heparan sulfate19
IER3: exploring its dual function as an oncogene and tumor suppressor19
Structural regulation of PLK1 activity: implications for cell cycle function and drug discovery19
CRISPR-Cas gene knockouts to optimize engineered T cells for cancer immunotherapy18
Transactivation of Met signaling by oncogenic Gnaq drives the evolution of melanoma in Hgf-Cdk4 mice18
CASC4/GOLM2 drives high grade serous carcinoma anoikis resistance through the recycling of EGFR18
Target therapeutic exploitation of engineered exosome-mediated delivery of ncRNAs in cancer18
TFF3 sensitizes cervical carcinoma cells to cisplatin toxicity by binding to IGF2R18
Knock-out of 5-lipoxygenase in overexpressing tumor cells—consequences on gene expression and cellular function18
SOCS3 inhibiting JAK-STAT pathway enhances oncolytic adenovirus efficacy by potentiating viral replication and T-cell activation17
WWOX binds MERIT40 and modulates its function in homologous recombination, implications in breast cancer17
Effective delivery of genome editor to cervical cancer targeting Mcl1 for cancer therapy16
Proteomic profiling reveals ACSS2 facilitating metabolic support in acute myeloid leukemia16
Utilizing nullomers in cell-free RNA for early cancer detection16
Therapeutic potential of synthetic microRNA mimics based on the miR-15/107 consensus sequence16
Inhibiting CXCL12/CXCR4 axis enhances T cell activity in gastric cancer16
Blocking tri-methylguanosine synthase 1 (TGS1) stops anchorage-independent growth of canine sarcomas15
Correction: Arsenic trioxide and p97 inhibitor synergize against acute myeloid leukemia by targeting nascent polypeptides and activating the ZAKα–JNK pathway15
SPP1+ TAM subpopulations in tumor microenvironment promote intravasation and metastasis of head and neck squamous cell carcinoma15
HPV status represents dominant trait driving delineation of survival-associated gene co-expression networks in head and neck cancer15
Correction to: Single-cell RNA sequencing reveals changes in glioma-associated macrophage polarization and cellular states of malignant gliomas with high AQP4 expression15
FOXM1 promotes neurofibromatosis type 1-associated malignant peripheral nerve sheath tumor progression in a NUF2-dependent manner15
STAT5a and SH2B3 novel mutations display malignancy roles in a triple-negative primary myelofibrosis patient15
GPR107: A key driver of breast cancer invasion and metastasis through collagen IV modulation14
TSPAN1 inhibits metastasis of nasopharyngeal carcinoma via suppressing NF-kB signaling14
Integration of humanized ROBO1 CAR in PD-1 locus in natural killer cells delivers synergistic tumor-killing effect against non-small cell lung cancer14
Detection of (pre)cancerous colorectal lesions in Lynch syndrome patients by microsatellite instability liquid biopsy14
MBD1 protects replication fork stability by recruiting PARP1 and controlling transcription-replication conflicts14
Correction to: Nogo-B receptor increases glycolysis and the paclitaxel resistance of estrogen receptor-positive breast cancer via the HIF-1α-dependent pathway14
Integrating system biology and intratumor gene therapy by trans-complementing the appropriate co-stimulatory molecule as payload in oncolytic herpes virus14
An alternative fully human anti-BCMA CAR-T shows response for relapsed or refractory multiple myeloma with anti-BCMA CAR-T exposures previously14
The long-term effectiveness and mechanism of oncolytic virotherapy combined with anti-PD-L1 antibody in colorectal cancer patient14
Activating NRF2E79Q mutation alters the differentiation of human non-small cell lung cancer14
Long noncoding RNA LINC00173 induces radioresistance in nasopharyngeal carcinoma via inhibiting CHK2/P53 pathway14
RevCAR-expressing immune effector cells for targeting of Fn14-positive glioblastoma14
Gastrointestinal infections and gastrointestinal haemorrhage are underestimated but serious adverse events in chimeric antigen receptor T-cell recipients: A real-world study14
MALNC: a new mutant NPM1/IDH2R140 and PML-RARA-associated lncRNA with impact on AML cell proliferation, maturation and drug response14
A novel intranasal peptide vaccine inhibits non-small cell lung cancer with KRAS mutation14
Estrogen receptor status heterogeneity in breast cancer tumor: role in response to endocrine treatment13
Identification of lineage-specific epigenetic regulators FOXA1 and GRHL2 through chromatin accessibility profiling in breast cancer cell lines13
SPARC family proteins: matricellular modulators of cancer progression and therapeutic resistance13
GAS5 attenuates the malignant progression of glioma stem-like cells by promoting E-cadherin13
Integrated multidimensional bioinformatics analysis of the molecular mechanisms of ulcerative colitis-associated colorectal cancer and MMP1 as a potential therapeutic target13
Clathrin-associated SCYL2 contributes to the activation of PI3K/AKT signaling and tumorigenesis through PTEN phosphorylation in adult T-cell leukemia/lymphoma13
Transcriptomic profiling of a novel gastric implantation model identifies mechanisms and pathways that drive implantation into explanted human peritoneum13
Engineered L-asparaginase variants with enhanced therapeutic properties to improve treatment of childhood acute lymphatic leukemia13
Retraction Note: microRNA-133a exerts tumor suppressive role in oral squamous cell carcinoma through the Notch signaling pathway via downregulation of CTBP213
Oleuropein regulates ubiquitination-mediated Mcl-1 turnover and exhibits antitumor activity13
Clonal dynamics limits detection of selection in tumour xenograft CRISPR/Cas9 screens13
Microbiota in tumors: new factor influencing cancer development13
New insights into the classification of the RAC1 P29S hotspot mutation in melanoma as an oncogene13
Anti-angiogenesis and anti-immunosuppression gene therapy through targeting COUP-TFII in an in situ glioblastoma mouse model13
Cell-intrinsic platinum response and associated genetic and gene expression signatures in ovarian cancer13
Editorial Expression of Concern: Herpes simplex virus thymidine kinase/ganciclovir–induced cell death is enhanced by co-expression of caspase-3 in ovarian carcinoma cells12
Olfactomedin 4 produces dysplasia but suppresses metastasis of colon cancer12
m6A-modified circFOXK2 targets GLUT1 to accelerate oral squamous cell carcinoma aerobic glycolysis12
RUNX1A isoform is overexpressed in acute myeloid leukemia and is associated with FLT3 internal tandem duplications12
Suicide gene strategies applied in ovarian cancer studies12
Therapeutic targeting of the tryptophan-kynurenine-aryl hydrocarbon receptor pathway with apigenin in MED12-mutant leiomyoma cells12
Redefining bioactive small molecules from microbial metabolites as revolutionary anticancer agents12
Identification of a novel prognostic ADME-related signature associated with tumor immunity for aiding therapy in head and neck squamous cell carcinoma12
Anti-leukemia effects of omipalisib in acute myeloid leukemia: inhibition of PI3K/AKT/mTOR signaling and suppression of mitochondrial biogenesis12
Correction: Pan-cancer oncogenic properties and therapeutic potential of SF3B412
GTF2E2 downregulated by miR-340-5p inhibits the malignant progression of glioblastoma12
Tumor stroma-derived ANGPTL2 potentiates immune checkpoint inhibitor efficacy12
Abemaciclib impairs glioblastoma sphere formation by targeting the GSK3β-mediated transcriptional regulation of CD44 and TCF7L211
Atypical phosphatase DUSP11 inhibition promotes nc886 expression and potentiates gemcitabine-mediated cell death through NF-kB modulation11
Pals1 functions in redundancy with SMAP1 to inhibit Arf6 in order to prevent Rac1-dependent colorectal cancer cell migration and invasion11
Single-nucleus and spatial transcriptomics analyses reveal interplay between evolutionary dynamics and energy metabolism in primary cardiac lymphoma11
LncSNHGs: new targets in osteosarcoma11
Improving the cytotoxic response of tumor-infiltrating lymphocytes towards advanced stage ovarian cancer with an oncolytic adenovirus expressing a human vIL-2 cytokine11
The dual role of GPX4 in breast cancer: mechanisms of therapeutic resistance and potential for novel targeted therapies11
CILP is a potential pan-cancer marker: combined silico study and in vitro analyses11
FBXO22 promotes HCC angiogenesis and metastasis via RPS5/AKT/HIF-1α/VEGF-A signaling axis11
IGH repertoire analysis at scale: deciphering the complexity of B cell infiltration and migration in esophageal squamous cell carcinoma11
Unveiling mitochondrial and ribosomal gene deregulation and tumor microenvironment dynamics in acute myeloid leukemia11
Cleavage and polyadenylation machinery as a novel targetable vulnerability for human cancer11
Long non-coding RNAs and signaling networks in non-small cell lung cancer: mechanistic insights into tumor pathogenesis11
Methylstat sensitizes ovarian cancer cells to PARP-inhibition by targeting the histone demethylases JMJD1B/C11
Retraction Note: circ_001504 promotes the development of renal cell carcinoma by sponging microRNA-149 to increase NUCB211
Predicting colorectal cancer risk in FAP patients using patient-specific organoids10
Has_circ_ASH1L acts as a sponge for miR-1254 to promote the malignant progression of cervical cancer by targeting CD3610
DR1 activates histone gene expression to maintain pancreatic cancer cell survival through the ATAC complex10
NCBP1 promotes the malignant progression of Wilms’ tumor through stabilization of KPNA2 mRNA10
Blood-brain barrier breakdown in traumatic brain injury: current insights and future directions10
The role of hsa_circ_0000520 in breast cancer progression: insights into the miR-542-3p/TMBIM6 regulatory axis10
3-Bromopyruvate overcomes cetuximab resistance in human colorectal cancer cells by inducing autophagy-dependent ferroptosis10
METTL3 facilitates colorectal cancer growth through altering the abundance of intestinal Akkermansia muciniphila10
Correction: PARD6A promotes lung adenocarcinoma cell proliferation and invasion through Serpina39
Targeting MTPN sensitizes pancreatic cancer of wild-type BRCA1/2 to Cisplatin-based chemotherapy9
BAIAP2L2 promotes the malignancy of hepatocellular carcinoma via GABPB1-mediated reactive oxygen species imbalance9
Role of MARK2 in the nervous system and cancer9
SEMA7A-mediated juxtacrine stimulation of IGFBP-3 upregulates IL-17RB at pancreatic cancer invasive front9
SMARCB1-driven EGFR-GLI1 epigenetic alterations in lung cancer progression and therapy are differentially modulated by MEOX2 and GLI-19
Retraction Note: Targeting KDM1B-dependent miR-215-AR-AGR2-axis promotes sensitivity to enzalutamide-resistant prostate cancer9
Reductive cell death: the other side of the coin9
Immuno-regulatory malignant B cells contribute to Chronic Lymphocytic Leukemia progression9
YAP 5-methylcytosine modification increases its mRNA stability and promotes the transcription of exosome secretion-related genes in lung adenocarcinoma9
The TCR in CAR T cell therapy: use it or lose it?9
Targeting CREB-binding protein (CBP) abrogates colorectal cancer stemness through epigenetic regulation of C-MYC9
CCR3 blockage elicits polyploidization associated with the signatures of epithelial-mesenchymal transition in carcinoma cell lines9
Hsa_circ_0013561 promotes epithelial-mesenchymal transition and tumor progression by regulating ANXA2 via miR-23b-3p in ovarian cancer9
Cancer-derived exosomal miR-375 targets DIP2C and promotes osteoblastic metastasis and prostate cancer progression by regulating the Wnt signaling pathway9
Cancer-associated fibroblast exosomes promote prostate cancer metastasis through miR-500a-3p/FBXW7/HSF1 axis under hypoxic microenvironment9
Bacterial nanoparticles as a potent and safe alternative to BCG for bladder cancer immunotherapy9
Recent advances in the role of circRNA in cisplatin resistance in tumors9
Using RNA-seq for detecting MRD in multiple myeloma: high sensitivity and prognostic value9
Silencing TRAIP suppresses cell proliferation and migration/invasion of triple negative breast cancer via RB-E2F signaling and EMT9
Characterization of tertiary lymphoid structure identifies competitive binding of CD40 and STING with TRAF2 driving IRF4-mediated B cell activation in esophageal squamous cell carcinoma9
ITGA3 promotes pancreatic cancer progression through HIF1α- and c-Myc-driven glycolysis in a collagen I-dependent autocrine manner8
Caveolin-1 knockout mitigates breast cancer metastasis to the lungs via integrin α3 dysregulation in 4T1-induced syngeneic breast cancer model8
Respective roles of Pik3ca mutations and cyproterone acetate impregnation in mouse meningioma tumorigenesis8
Correction to: Activation of CEACAM1 with an agonistic monoclonal antibody results in inhibition of melanoma cells8
Research progress and application of single-cell sequencing in head and neck malignant tumors8
Long non-coding RNA PRSS23-AS1 as ceRNA promotes breast cancer progression by regulating EMT via miR-3176 /YBX1 axis8
The role of LncRNA-MANCR induced by HIF-1α drive the malignant progression of pancreatic cancer by targeting miRNA-494/SIRT1 signaling axis under hypoxic conditions8
Exploring metabolic reprogramming in esophageal cancer: the role of key enzymes in glucose, amino acid, and nucleotide pathways and targeted therapies8
Correction: Transcriptomic profiling of a novel gastric implantation model identifies mechanisms and pathways that drive implantation into explanted human peritoneum8
NF-κB-activated oncogene inhibition strategy for cancer gene therapy8
Oncolytic HSV1 targets different growth phases of breast cancer leptomeningeal metastases8
ATPase copper transporting beta contributes to cisplatin resistance as a regulatory factor of extracellular vesicles in head and neck squamous cell carcinoma8
c-Myc-induced long noncoding RNA MIRE cooperates with hnRNPK to stabilize ELF2 mRNA and promotes clear cell renal cell carcinogenesis8
APOE deficiency triggers anti-tumour activity of macrophages in liver cancer8
Therapeutic applications of local injection of hsa-miR-634 into canine spontaneous malignant melanoma tumors8
Pharmacological targeting of CBP/p300 drives a redox/autophagy axis leading to senescence-induced growth arrest in non-small cell lung cancer cells8
Disulfidptosis in cancer: from redox stress to therapeutic strategy8
Baicalein inhibits cell proliferation and induces apoptosis in brain glioma cells by downregulating the LGR4-EGFR pathway8
Novel long noncoding RNA LINC02820 augments TNF signaling pathway to remodel cytoskeleton and potentiate metastasis in esophageal squamous cell carcinoma8
The splicing factor SF3B1 confers ferroptosis resistance and promotes lung adenocarcinoma progression via upregulation of SLC7A118
The pleiotropic nature of NONO, a master regulator of essential biological pathways in cancers7
CEACAM6 facilitates gastric cancer progression through upregulating SLC27A27
LINC00665 activating Wnt3a/β-catenin signaling by bond with YBX1 promotes gastric cancer proliferation and metastasis7
Histone 3 lysine 9 acetylation-specific reprogramming regulates esophageal squamous cell carcinoma progression and metastasis7
UGT1A7 altered HER2-positive breast cancer response to trastuzumab by affecting epithelial-to-mesenchymal transition: A potential biomarker to identify patients resistant to trastuzumab treatment7
Retraction Note: Nrf2 overexpression increases the resistance of acute myeloid leukemia to cytarabine by inhibiting replication factor C47
Retraction Note: Cabozantinib induces PUMA-dependent apoptosis in colon cancer cells via AKT/GSK-3β/NF-κB signaling pathway7
Therapeutic activity of retroviral replicating vector-mediated gene therapy in combination with anti-PD-1 antibody in a murine pancreatic cancer model7
Small molecule-induced epigenomic reprogramming of APL blasts leading to antiviral-like response and c-MYC downregulation7
Construction of the cancer cell continuum reveals hybrid EMT state driving lung adenocarcinoma aggression7
LMTK3 regulates breast cancer angiogenesis via a context-dependent mesenchymal-epithelial transition program7
Identification of KIFC1 as a putative vulnerability in lung cancers with centrosome amplification7
β3-adrenergic receptor on tumor-infiltrating lymphocytes sustains IFN-γ-dependent PD-L1 expression and impairs anti-tumor immunity in neuroblastoma7
SATB1 regulates TXNIP inhibiting invasion and infiltration in T-cell acute lymphoblastic leukemia7
HN1-mediated activation of lipogenesis through Akt-SREBP signaling promotes hepatocellular carcinoma cell proliferation and metastasis7
Glioblastoma glycolytic signature predicts unfavorable prognosis, immunological heterogeneity, and ENO1 promotes microglia M2 polarization and cancer cell malignancy7
Transcription factor YY1 mediates self-renewal of glioblastoma stem cells through regulation of the SENP1/METTL3/MYC axis7
CLK3 regulates tumor angiogenesis by modulating HIF1α ubiquitination7
SPRTN is involved in hepatocellular carcinoma development through the ER stress response7
Emerging roles of prohibitins in cancer: an update6
Carboxyl-terminal modulator protein facilitates tumor metastasis in triple-negative breast cancer6
Heparanase interacting BCLAF1 to promote the development and drug resistance of ICC through the PERK/eIF2α pathway6
miR-451a was selectively sorted into exosomes and promoted the progression of esophageal squamous cell carcinoma through CAB396
Overcoming biophysical barriers with innovative therapeutic delivery approaches6
ALKBH5-mediated m6A regulates the alternative splicing events of SRSF10 in ovarian cancer6
Regulation of tumor metabolism by post translational modifications on metabolic enzymes6
The function of brother of the regulator of imprinted sites in cancer development6
Phosphoglycerate mutase 1 promotes breast cancer progression through inducing immunosuppressive M2 macrophages6
Promoting the therapeutic potential of interleukin-7 (IL-7) by expression in viral vectors6
Patient-derived tumor models: a suitable tool for preclinical studies on esophageal cancer6
Multifaceted role of microRNA-301a in human cancer: from biomarker potential to therapeutic targeting6
A novel subclonal rearrangement of the STRN3::PDGFRB gene in de novo acute myeloid leukemia with NPM1 mutation and its leukemogenic effects6
High CAR intensity of expression confers enhanced antitumor effect against lymphoma without functional exhaustion6
Recent progress of CDK4/6 inhibitors’ current practice in breast cancer6
The effects of intracellular and exosomal ncRNAs on cancer progression6
Genetic trajectory and clonal evolution of multiple primary lung cancer with lymph node metastasis6
Divergent transcriptomic signatures from putative mesenchymal stimuli in glioblastoma cells6
RAB3D/MDM2/β-catenin/c-MYC axis exacerbates the malignant behaviors of acute myeloid leukemia cells in vitro and in vivo6
TMTC1 promotes invasiveness of ovarian cancer cells through integrins β1 and β46
Novel pharmacologic inhibition of lysine-specific demethylase 1 as a potential therapeutic for glioblastoma5
Dickkopf-1 (DKK1) drives growth and metastases in castration-resistant prostate cancer5
Amplified therapeutic targets in high-grade serous ovarian carcinoma – a review of the literature with quantitative appraisal5
A multi-omics integrative approach unravels novel genes and pathways associated with senescence escape after targeted therapy in NRAS mutant melanoma5
Deciphering the role of post-translational modifications in fanconi anemia proteins and their influence on tumorigenesis5
Inhibition of orthotopic castration-resistant prostate cancer growth and metastasis in mice by JC VLPs carrying a suicide gene driven by the PSA promoter5
Targeting SOD1 via RNAi with PEGylated graphene oxide nanoparticles in platinum-resistant ovarian cancer5
Retraction Note: BET inhibitor I-BET151 sensitizes GBM cells to temozolomide via PUMA induction5
Understanding, diagnosing, and treating pancreatic cancer from the perspective of telomeres and telomerase5
LD–associated signatures identified by perilipin-based proximity labeling proteomics reveal GNA14 as a therapeutic and prognostic target in renal cell carcinoma5
Inducible TgfbR1 and Pten deletion in a model of tongue carcinogenesis and chemoprevention5
Loss of exosomal miR-200b-3p from hypoxia cancer-associated fibroblasts promotes tumorigenesis and reduces sensitivity to 5-Flourouracil in colorectal cancer via upregulation of ZEB1 and E2F35
Mesenchymal stem cells as therapeutic vehicles for glioma5
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