OOIR: Observatory of International Research

Papers

(The TQCC of Protein and Peptide Letters is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
FOXN3 Expression Regulated by miR-299-5p Inhibiting the Proliferation, Migration and Invasion of Oral Squamous Cell Carcinoma Cells	43
Water-soluble Moringa oleifera Seed Lectin Exhibits Monoaminergic Pathway-linked Anti-depressive-like Effects in Mice	34
Amplification of Amyloid Protein-induced Aggregation of the Eukaryotic Ribosome	22
The Sensitive Genes in Response to Various Metal Ion Stresses in the Yeast Saccharomyces cerevisiae	22
Heat-Shock Triggers Inverted Induction of Hypo-S-Nitrosylation and Hyper-O-GlcNAcylation	18
Effects of Glutathionylation on Guanylyltransferase Activity of NS5 N-terminal Capping Domain from Dengue, Japanese Encephalitis, and Zika Viruses	17
Beyond B-Cell Epitopes: Curating Positive Data on Antipeptide Paratope Binding to Support Peptide-Based Vaccine Design	14
Understanding Protein Functions in the Biological Context	12
Molecular Interactions of the Antimicrobial Peptide Tritrpticin with Mixed Nanoaggregates: A Fluorescence Spectroscopy Study	12
Structural Shifts of the Parvovirus B19 Capsid Receptor-binding Domain: A Peptide Study	12
Inhibition of Canonical Wnt Signaling in Renal Cell Carcinoma Bone Metastasis: An Immunohistochemical Analysis of DKK1 and LRP5 Expression	11
An Overview of the Role of Membrane Proteins in Microbial Solvents Tolerance	11
Genome-Wide Association Studies (GWAS) for Traits Related to Fodder Quality and Biofuel in Sorghum: Progress and Prospects	10
HSP90-regulated CHIP/TRIM21/p21 Axis Involves in the Senescence of Osteosarcoma Cells	10
Increased Expression of Recombinant Chitosanase by Co-expression of Hac1p in the Yeast Pichia pastoris	10
The Application of a Recombinant Antimicrobial Peptide of Thrombocidin-1 Expressed in Pichia pastoris as a Novel Approach Against Some Oral Pathogenic Bacteria: An In Vitro Study	9
Plasma/Serum Proteomics based on Mass Spectrometry	9
Current Trends and Applications of Food-derived Antihypertensive Peptides for the Management of Cardiovascular Disease	9
Comprehensive Analysis of lncRNA and mRNA Expression Profile of Macrophage RAW264.7 Stimulated by Antimicrobial Peptide BSN-37	8
LINC01836 Promotes Colorectal Cancer Progression and Functions as ceRNA to Target SLC17A9 by Sponging miR-1226-3p	8
Construction and Evaluation of Recombinant Chimeric Fibrillin and Elastin Fragment in Human Mesenchymal Stem Cells	8
Plant Terpenes on Treating Cardiovascular and Metabolic Disease: A Review	8
Protein Tyrosine Phosphatase Receptor-type Q: Structure, Activity, and Implications in Human Disease	8
The Implication of Hypocretin in Drug Abuse and Arousal in the Brain Stem	8
ZP3 Expression in Pancreatic Adenocarcinoma: Its Implications for the Prognosis and Therapy	8

Unraveling the Role of Functional Amyloids and Amyloid Peptides in Disease Detection	7
Unveiling the Molecular Mechanism of Diosmetin and its Impact on Multifaceted Cellular Signaling Pathways	7
Human Serum Albumin Aggregation and its Modulation Using Nanoparticles: A Review	7
UPBEAT1-ROS-POD-PAL System under Different Xylogenesis Scenarios in Karelian Birch (Betula pendula Roth var. carelica (Mercl.) Hämet-Ahti)	7
Neuropeptide Network of Polycystic Ovary Syndrome – A Review	7
Association between Higher Expression of Vav1 in Hepatocellular Carcinoma and Unfavourable Clinicopathological Features and Prognosis	7
SNHG3/miR-330-5p/HSD11B1 Alleviates Myocardial Ischemia-reperfusion Injury by Regulating the ERK/p38 Signaling Pathway	7
Investigation of Early Growth Response Protein (EGR) Levels in Patients with Fibromyalgia Syndrome: A Cross-Sectional Study	7
Binding of l-Anilino-8-Napthalenesulfonate to Free and Coformycin-Complexed Bovine Adenosine Deaminase	7
Improved Soluble Expression in Escherichia coli and Easily Purified Recombinant Human Bone Morphogenetic 7-2 Fusion Protein	7
A Review of Gap Junction Protein and its Potential Role in Nervous System-Related Disease	7
Trypsin/α-Amylase Inhibitors from Capsicum chinense Seeds: Characterization and Antifungal Activity against Fungi of Agronomic Importance	7
Variable Surface Antigens of Plasmodium falciparum: Protein Families with Divergent Roles	7
Molecular Bases of Protein Antigenicity and Determinants of Immunogenicity, Anergy, and Mitogenicity	7
Potassium Channels Contributes to Apelin-induced Vasodilation in Rat Thoracic Aorta	7
Synthesis of Two Designed Hairprin Peptides on a Newly Developed 1,6-Hexanediol Diacrylate (HDODA)-Crosslinked Polystyrene Resin	7
Gelsolin Inhibits the Proliferation of Colon Cancer Cells by Enhancing the Expression of TNFR2/CASP10 as a Death Receptor Pathway	6
Regulatory Mechanism of lncRNA CTBP1-AS2 in Nasopharyngeal Carcinoma Cell Proliferation and Apoptosis via the miR-140-5p/BMP2 Axis	6
Targeting APE1: Advancements in the Diagnosis and Treatment of Tumors	6
Oral Angiotensin-(1-7) Peptide Modulates Intestinal Microbiota Improving Metabolic Profile in Obese Mice	6
Neuroprotective Effect of Dexmedetomidine Pretreatment on Sevoflurane- Initiated Neurotoxicity Via the Mir-204-5p/SOX4 Axis	6
Dexmedetomidine Alleviates Brain Ischemia/Reperfusion Injury by Regulating Metastasis-associated Lung Adenocarcinoma Transcript 1/MicroRNA-140-5p/ Nuclear Factor Erythroid-derived 2-like 2 Axis	6
A Review on Recent Advancement in Expression Strategies Used in Bacillus subtilis	6
Preface	6
Guanidinium-based Integrated Peptide Dendrimers: Pioneer Nanocarrier in Cancer Therapy	6
Knockdown of Programmed Death 1 Inhibited Progression of Papillary Thyroid Carcinoma in Mice	5
Identifying the Role of Individual Seal IAPP Amino Acids in Inhibiting the Aggregation of Human IAPP	5
Database Study on the Expression and Purification of Membrane Proteins	5
Lessons Learnt and the Way Forward for Drug Development Against Isocitrate Lyase from Mycobacterium tuberculosis	5
Insights into Coronavirus Papain-like Protease Structure, Function and Inhibitors	5
Feasibility of Domain Segmentation of B19V VP1u Using Intein Technology for Structural Studies	5
P53-induced GAP-43 Upregulation in Primary Cortical Neurons of Rats	5
Meclofenoxate Inhibits Aggregation of Alpha-synuclein in vitro	5
Screening of MMP-2 Inhibiting Phytoconstituents for the Development of Newer Pancreatic Cancer Treatment Modalities	5
Modified Levels of Renin Angiotensin Related Components in the Frontal Cortex and Hippocampus were Associated with Neuroinflammation and Lower Neuroprotective Effects of NGF During Acute Hepatic Encep	5
Effect of Propeptide Mutations on the Directed Evolution of Rhizomucor miehei Lipase	5
Unidentified N-glycans by N-glycosidase A were Identified by Nglycosidase F under Denaturing Conditions in Plant Glycoprotein	5
Structural and Functional Analysis of Urease Accessory Protein E from Vancomycin-Resistance Staphylococcus aureus MU50 Strain	5
Thermodynamics of the Association of Aminoglycoside Antibiotics with Human Angiogenin	5
Cold-Induced RNA-Binding Protein and RNA-Binding Motif Protein 3: Two RNA Molecular Chaperones Closely Related to Reproductive Development and Reproductive System Diseases	5
Methods of PARP-1 Determination and its Importance in Living Organisms	5
Applications of Plant Proteinase Inhibitors in Agriculture	5
Preparation of IgE Antibody and Distribution of IgE+ Secretory Cells in the Palatine Tonsil of Bactrian Camel	5
Wogonin Restrains the Malignant Progression of Lung Cancer Through Modulating MMP1 and PI3K/AKT Signaling Pathway	5
Concentration-mediated Folding and Unfolding of Collagen Triple Helix	4
Some Minor Characteristics of Spectrophotometric Determination of Antioxidant System and Phenolic Metabolism Enzyme Activity in Wood Plant Tissues of Pinus sylvestris L.	4
Plastid Transcriptomics: An Important Tool For Plastid Functional Genomics	4
Insights into the Dynamic Fluctuations of the Protein HPV16 E1 and Identification of Motifs by Using Elastic Network Modeling	4
The LL-37 Antimicrobial Peptide as a Treatment for Systematic Infection of Acinetobacter baumannii in a Mouse Model	4
Graphenoxide Cross-Linker Based Potentiometric Biosensor Design for Sarcosine Determination	4

Comparison of Adjuvant Effects of Montanide ISA-720 and Heat Shock Protein 27 in Increasing Immunostimulatory Properties of HIV-1 Nef-Vif Fusion Protein Construct	4
Proteomic Analysis of the Colistin-resistant E. coli Clinical Isolate: Explorations of the Resistome	4
In Silico Analysis of Natural Plant-Derived Cyclotides with Antifungal Activity against Pathogenic Fungi	4
Design, Synthesis and DNA-Binding Activities of GCN4 Peptide Dimer Studied by Circular Dichroism Spectroscopy	4
Lactococcus lactis and Resveratrol Decrease Body Weight and Increase Benefic Gastrointestinal Microbiota in Mice	4
Mesenchymal Stem Cell Derived-Exosomes as Effective Factors in Reducing Cytokine Storm Symptoms of COVID-19	4
Natural Amphibian-Derived Host Defense Peptides: Peptide Immunomodulators with Potential Therapeutic Value	4
Characterization of a Novel Thermostable 7α-Hydroxysteroid Dehydrogenase	4
Development of a Peptide-Based Multiepitope Vaccine from the SARS-CoV-2 Spike Protein for Targeted Immune Response Against COVID-19	4
Applications of CRISPR Cas-9 in Ovarian Cancer Research	4
Expression and Purification of His-Tagged Variants of Human Hepatitis A Virus 3C Protease	4
Interaction of the Seed Lectin from Parkia Platycephala (Mimosoideae) with Carbohydrates and Complex Glycans	4
Disruption of Staphylococcus aureus Biofilms with Purified Moringa oleifera Leaf Extract Protein	4
Combining Network Pharmacology, Molecular Docking and Preliminary Experiments to Explore the Mechanism of Action of FZKA Formula on Non-small Cell Lung Cancer	4
Structural Analysis Revealed the Interaction of Cardenolides from Calotropis procera with Na+/K+ ATPases from Herbivores	4
The Agonistic Activity of the Human Epidermal Growth Factor is Reduced by the D46G Substitution	4
A Functional Human Glycogen Debranching Enzyme Encoded by a Synthetic Gene: Its Implications for Glycogen Storage Disease Type III Management	4
Design of Artificial C-Peptides as Potential Anti-HIV-1 Inhibitors Based on 6-HB Formation Mechanism	4
Proteomic Analysis of Glucose-Induced Cardiac Myoblasts and the Potential Role of mir-92b-5p in Regulating Sarcomere Proteins Under a Hyperglycemic Environment	4
Antimicrobial Peptides: An Overview of their Structure, Function and Mechanism of Action	4
Strategy for the Enrichment of Protein Biomarkers from Diverse Bacterial Select Agents	4
Biochemical Aspects of the Spiral Grain Formation in Scots Pine (Pinus Sylvestris L.) Wood. Some Differences and Similarities with Biochemical Indicators of Abnormal Xylogenesis in Karelian Birch (Bet	3
An Overview of 7α- and 7β-Hydroxysteroid Dehydrogenases: Structure, Specificity and Practical Application	3
Hsa_circ_0000437 Inhibits the Development of Endometrial Carcinoma through miR-626/CDKN1B Axis	3
Corrigendum to: Investigation of the Expression and Regulation of SCG5 in the Context of the Chromogranin-Secretogranin Family in Malignant Tumors	3
Structure of Cadmiull}-Substituted Phospholipase A2 from Agkistrodon halys Pallas at 2.8A Resolution	3
The Roles of Ciliary Neurotrophic Factor - from Neuronutrition to Energy Metabolism	3
Design, Expression, and Purification of a Fusion Enzyme Containing Terminal Deoxynucleotidyl Transferase from B. bovis and DNA-Binding Proteins from E. coli	3
MicroRNA-605-3p Inhibited the Growth and Chemoresistance of Osteosarcoma Cells via Negatively Modulating RAF1	3
Mimicking LysC Proteolysis by ‘Arginine Modification-cum-Trypsin Digestion’: Comparison of Bottom-up & Middle-down Proteomic Approaches by ESI Q-TOF MS	3
Cyclopeptide-based Anti-liver Cancer Agents: A Mini-review	3
Participation of CWINV and SUS Genes in Sucrose Utilization in the Disruption of Cambium Derivatives Differentiation of Silver Birch	3
Anticancer and Antimicrobial Evaluations on Alternative Reading Frame (ARF) Peptides and their Derivatives	3
Production of Soluble Murine TRAILs in Escherichia coli with Zn²⁺ Supplementation	3
Structural Phylogeny of Different Allergens May Reveal Common Epitopic Footprint	3
The Features of Shared Genes among Transcriptomes Probed in Atopic Dermatitis, Psoriasis, and Inflammatory Acne: S100A9 Selection as the Target Gene	3
Plant-derived Cyclotides in Immunomodulation and their Therapeutic Potential	3
First Display of Haloalkane Dehalogenase LinB on the Surface of Bacillus subtilis Spore	3
Study on the Analgesic Activity of Peptide from Conus achates	3
Development of an Autoinducible Plasmid for Recombinant Protein Production	3
The Role of TGFBR3 in the Development of Lung Cancer	3
Boosting Auto-Induction of Recombinant Proteins in Escherichia coli with Glucose and Lactose Additives	3
Expression, Purification, and Evaluation of Antibody Responses and Antibody-Immunogen Complex Simulation of a Designed Multi-Epitope Vaccine against SARS-COV-2	3
Overview of Lignocellulolytic Enzyme Systems with Special Reference to Valorization of Lignocellulosic Biomass	3
Nonhuman IAPP Variants Inhibit Human IAPP Aggregation	3
Interaction of Synthetic Pyrethroid Insecticide Deltamethrin with Human Alpha-2-Macroglobulin: Spectroscopic and Molecular Docking Studies	3
Protein Arginine Methyltransferase 1 and its Dynamic Regulation Associated with Cellular Processes and Diseases	3
The Function and Modification of Human Defensin 5	3
Circ_0006789 Promotes the Progression of Hepatocellular Carcinoma Cells via Modulating miR-1324 and SOX12	3
Antioxidant Responses are Crucial for Defense against Misfolded Human Z-Type α₁-Antitrypsin	3
Process Development for the Production and Purification of PEGylated RhG-CSF Expressed in Escherichia coli	3
Exploring the Cell Wall and Secretory Proteins of Mycobacterium leprae as Biomarkers	3
Estrogen Sulfotransferase SULT1E1 Expression Levels and Regulated Factors in Malignant Tumours	3
Exploring the Potential Long-term Impact of SARS-CoV-2 on Protein Misfolding and Amyloid-related Conditions	3
Biophysical Insight into Protein Folding, Aggregate Formation and its Inhibition Strategies	3
Analysis of the Interaction of UBE2Q1 with B4GALT1 and P53: Experimental and Molecular Modeling Study	3
Preface	3
Circ_0008768 Suppresses the Pancreatic Cancer Progression via miR-330- 3p/PTEN Axis	3