OOIR: Observatory of International Research

Papers

(The TQCC of Protein and Peptide Letters is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Acknowledgements to Reviewers	40
Kinetics of Ca2+ Dissociation from Cod Parvalbumin Studied by Fluorescent Stopped-flow Method	26
ACE2 Receptor Polymorphism and its Correlation with Anti-SARS-CoV-2 IgM Antibodies - A Case-Control Study	22
Cationic Clitoria ternatea Seed Peptide as a Potential Novel Bioactive Molecule	21
Plastid Transcriptomics: An Important Tool For Plastid Functional Genomics	17
Amphibian-Derived Antimicrobial Peptides: Essential Components of Innate Immunity and Potential Leads for New Antibiotic Development	16
Exploring the Regulatory Interaction of Differentially Expressed Proteins in Cleft Palate Induced by Retinoic Acid	12
Recombinant Production of Ib-AMP₄ and Oncorhyncin II Antimicrobial Peptides and Antimicrobial Synergistic Assessment on the Treatment of Staphylococcus aureus Under In vitro Condition	12
Molecular Interactions of the Antimicrobial Peptide Tritrpticin with Mixed Nanoaggregates: A Fluorescence Spectroscopy Study	12
Understanding the Molecular Basis for Enhanced Glutenase Activity of Actinidin using Structural Bioinformatics	10
Phosphoserine Aminotransferase has Conserved Active Site from Microbes to Higher Eukaryotes with Minor Deviations	10
Interaction of the Seed Lectin from Parkia Platycephala (Mimosoideae) with Carbohydrates and Complex Glycans	10
Proteomic Analysis of the Colistin-resistant E. coli Clinical Isolate: Explorations of the Resistome	10
Simultaneous Optimization of Activity and Stability of Xylose Reductase from D. nepalensis NCYC 3413 Using Statistical Experimental Design	10
Purification and Characterization of Thermostable α-Amylase from Soil Bacterium Bacillus sp.	9
iRGD Tumor Penetrating Peptide-Modified NK Cells Exhibit Enhanced Tumor Immune Infiltration Ability and Anti-Tumor Efficacy	8
miR-584-5p Regulates MSMO1 to Modulate the AKT/PI3K Pathway and Inhibit Breast Cancer Progression	8
Anti-Cancer Bioactive Peptide Induces Apoptosis in Gastric Cancer Cells through TP53 Signaling Cascade	8
Tribute to Prof. Ben M. Dunn: A Remarkable Biochemist and Editor-in-Chief of Protein & Peptide Letters and Current Protein & Peptide Science	8
A Review on the Potential Role of Humanin Peptide and its Analogs in the Regulation of Autophagy Pathways for Therapeutic Application in Metabolic Disorders	8
Plant Proteogenomics Research	8
N-Terminal Pro-C-Type Natriuretic Peptide: The Novel Marker in Selected Disease Units	7
Pathways Related to the Anti-Cancer Effects of Metabolites Derived from Cerrado Biome Native Plants: An Update and Bioinformatics Analysis on Oral Squamous Cell Carcinoma	7
Lactococcus lactis and Resveratrol Decrease Body Weight and Increase Benefic Gastrointestinal Microbiota in Mice	7
An Insight into the Protein Aggregation in Alzheimer’s Disease and its Inhibition	7

Hepatotoxic Effect of Lafoensia pacari A. St. Hil. (Lythraceae) on a Diet-Induced Obese Mice Model	7
Characterization of a Novel Protease Inhibitor from the Edible MushroomAgaricus bisporus	7
Mesenchymal Stem Cell Derived-Exosomes as Effective Factors in Reducing Cytokine Storm Symptoms of COVID-19	7
Combining Network Pharmacology, Molecular Docking and Preliminary Experiments to Explore the Mechanism of Action of FZKA Formula on Non-small Cell Lung Cancer	7
Protease Inhibitors (PIs): Candidate Molecules for Crop Protection Formulations against Necrotrophs	7
Galectin-3 and Severity of Liver Fibrosis in Metabolic Dysfunction-Associated Fatty Liver Disease	7
Insights into the Structural Features, Conformational Stability and Functional Activity of the Olneya tesota PF2 Lectin	7
Circ_0002762 Regulates Oncoprotein YBX1 in Cervical Cancer via mir-375 to Regulate the Malignancy of Cancer Cells	7
Immunoproteomics: A Review of Techniques, Applications, and Advancements	7
Protein A and CaptureSelect FcXP Affinity Resins Possess the Capability of Differentiating Hole-hole Homodimer Isoforms	7
Structural Shifts of the Parvovirus B19 Capsid Receptor-binding Domain: A Peptide Study	7
The Sensitive Genes in Response to Various Metal Ion Stresses in the Yeast Saccharomyces cerevisiae	6
Effects of Glutathionylation on Guanylyltransferase Activity of NS5 N-terminal Capping Domain from Dengue, Japanese Encephalitis, and Zika Viruses	6
Porphyromonas gingivalis Lipopolysaccharide-Induced B Cell Differentiation by Toll-like Receptors 2 and 4	6
Thymic Immunosuppressive Pentapeptide (TIPP) Shown Anticancer Activity in Breast Cancer and Chronic Myeloid Leukemia Both In Vitro and In Vivo	6
Novel Post-translational Modifications in Human Serum Albumin	6
A Novel Reversibly Glycosylated Polypeptide-2 of Bee Pollen from Rape (Brassica napus L.): Purification and Characterization	6
Effects of Conjugation of Ferrocene and Gallic Acid On desCys11/Lys12/Lys13-(p-BthTX-I)2K Peptide: Structure, Permeabilization and Antibacterial Activity	6
Expression, Rapid Purification and Functional Analysis of DnaK from Rhodococcus ruber	6
Beyond B-Cell Epitopes: Curating Positive Data on Antipeptide Paratope Binding to Support Peptide-Based Vaccine Design	6
Natural Amphibian-Derived Host Defense Peptides: Peptide Immunomodulators with Potential Therapeutic Value	6
Characterization of Secondary Structure and Thermal Stability by Biophysical Methods of the D-alanyl,D-alanine Ligase B Protein from Escherichia coli	5
Attack Site Density of a Highly-efficient PET Hydrolases	5
Role of Fibrinogen in Type-2 Diabetes Mellitus with Diabetic Neuropathy and its Preliminary Mechanism	5
Aloperine Prevents Migration, Invasion, and Adhesion by Upregulating TIMP-4 in Human Bladder Cancer Cells	5
Biophysical Evidence for the Amyloid Formation of a Recombinant Rab2 Isoform of Leishmania donovani	5
Sequence Analysis and Biochemical Characteristics of Two Non-specific Lipid Transfer Proteins from Tartary Buckwheat Seeds	5
The Agonistic Activity of the Human Epidermal Growth Factor is Reduced by the D46G Substitution	5
Proteomic Analysis of Glucose-Induced Cardiac Myoblasts and the Potential Role of mir-92b-5p in Regulating Sarcomere Proteins Under a Hyperglycemic Environment	5
Biomarker of Pulmonary Inflammatory Response in LUAD: miR-584-5p Targets RAB23 to Suppress Inflammation Induced by LPS in A549 Cells	5
FOXN3 Expression Regulated by miR-299-5p Inhibiting the Proliferation, Migration and Invasion of Oral Squamous Cell Carcinoma Cells	5
Purification of Classical Swine Fever Virus E2 Subunit Vaccines Based on High Affinity Peptide Ligand	5
Self-Assembled KLD-12/SDF-1 Polypeptide Promotes Differentiation and Migration of BMSCs via the Wnt/β-catenin Signaling Pathways	5
Amplification of Amyloid Protein-induced Aggregation of the Eukaryotic Ribosome	4
Expression and Purification of Human Granzyme B Fusion Protein to Induce Targeted Apoptosis in PSMA Positive Prostate Cancer Cells	4
Angiotensin I-Converting Enzyme (ACE-I) Inhibition and Antioxidant Peptide from a Squilla Species	4
Structural Analysis Revealed the Interaction of Cardenolides from Calotropis procera with Na+/K+ ATPases from Herbivores	4
Transmembrane Protein 166 and its Significance	4
Utilization of SUMO Tag and Freeze-thawing Method for a High-level Expression and Solubilization of Recombinant Human Angiotensinconverting Enzyme 2 (rhACE2) Protein in E. coli	4
The Multifunction of TRIM26: From Immune Regulation to Oncology	4
Current Trends and Applications of Food-derived Antihypertensive Peptides for the Management of Cardiovascular Disease	4
Corrigendum to: Establishment and In Vitro Evaluation of Porous Ion-Responsive Targeted Drug Delivery System. Protein & Peptide Letters, volume 27(11), (2020)	4
Zika Virus NS2B-NS3 Protease: Quantum Chemical Properties Insights into Designing Inhibitory Peptides	4
Production and Functional Characterization of a Novel Mannanase from Alteromonadaceae Bacterium Bs31	4
Elucidation of PLK1 Linked Biomarkers in Oesophageal Cancer Cell Lines: A Step Towards Novel Signaling Pathways by p53 and PLK1-Linked Functions Crosstalk	4
In Silico Analysis of Natural Plant-Derived Cyclotides with Antifungal Activity against Pathogenic Fungi	4
Water-soluble Moringa oleifera Seed Lectin Exhibits Monoaminergic Pathway-linked Anti-depressive-like Effects in Mice	4
Acknowledgement to Reviewers	4
Advances in Research on Protein Arginine Methyltransferase 2: Functions and Diseases	4
Overexpression of HIF2α Enhances the Angiogenesis-Promoting Effect of hUC-MSC-Derived Extracellular Vesicles by Stimulating miR-146a	4

Physiological and Pathological Roles of NTSR2 in Several Organs and Diseases (Review)	4
Understanding Protein Functions in the Biological Context	4
Graphenoxide Cross-Linker Based Potentiometric Biosensor Design for Sarcosine Determination	4
An Indicating Role of Antioxidant System Enzymes at the Stage of Active Structural Anomalies Formation in Karelian Birch (Betula pendula Roth var. carelica (Mercl.) Hämet-Ahti)	4
Heat-Shock Triggers Inverted Induction of Hypo-S-Nitrosylation and Hyper-O-GlcNAcylation	4
LINC01836 Promotes Colorectal Cancer Progression and Functions as ceRNA to Target SLC17A9 by Sponging miR-1226-3p	4
The Implication of Hypocretin in Drug Abuse and Arousal in the Brain Stem	4
Preface	4
Purification and Crystallisation of a Novel Two-Domain Lectin from Scilla Campanulata	4
Zinc Promoted Simple Synthesis of Z-Arnino Acids Under Neutral Conditions	4
Some Minor Characteristics of Spectrophotometric Determination of Antioxidant System and Phenolic Metabolism Enzyme Activity in Wood Plant Tissues of Pinus sylvestris L.	3
Post-translational Modifications by Acyl Groups Regulate FEN1’s Activities and Play Essential Roles in Cell Proliferation and DNA Repair	3
Review of Evidence and Perspectives of Flavonoids on Metabolic Syndrome and Neurodegenerative Disease	3
Evaluation of the Cardioprotective Effect of Granulocyte Colony Stimulating Factor in Patients with Carbon Monoxide Poisoning	3
An Alternative Method for the Isolation and Identification of C-Terminal Peptide of Protein	3
Characterization and Expression Analysis of Resistance Gene Analogues in Elite Sugarcane Genotypes	3
Role of BLACAT1 in IL-1β-Induced Human Articular Chondrocyte Apoptosis and Extracellular Matrix Degradation via the miR-149-5p/ HMGCR Axis	3
An Overview on Functional and Structural Properties of Monomeric and Multimeric β-Thymosin in Invertebrates	3
HSP90-regulated CHIP/TRIM21/p21 Axis Involves in the Senescence of Osteosarcoma Cells	3
Protein Engineering, a Robust Tool to Engineer Novel Functions in Protein	3
Crystal Structure of a Cu,Zn Superoxide Dismutase From the Thermophilic Fungus Chaetomium thermophilum	3
Allergen Homologues, Pathogenesis-Related 1, Polygalacturonase, and Pectin Methyl Esterase from a Japanese Hop	3
Immunoproteomics: Approach to Diagnostic and Vaccine Development	3
Recombinant Expression and Characterization of Lemon (Citrus limon) Peroxidase	3
Plant Terpenes on Treating Cardiovascular and Metabolic Disease: A Review	3
SGSM2 in Uveal Melanoma: Implications for Survival, Immune Infiltration, and Drug Sensitivity	3
Novel Circular RNA CircUBAP2 Drives Tumor Progression by Regulating the miR-143/TFAP2B Axis in Prostate Cancer	3
Carboxyl-Terminal Sequencing: COOH-Amino Acid Activation with DCC or TBTU	3
NRSN2 is a Prognostic Biomarker in Gastric Cancer and Facilitates the Growth and Migration of Gastric Cancer Cells	3
Peptidomic Analysis and Antimicrobial Activity of Serum Peptide from Hevea brasiliensis Clone BPM24	3
Increased Expression of Recombinant Chitosanase by Co-expression of Hac1p in the Yeast Pichia pastoris	3
Proteomic Analysis by 4D Label-free MS-PRM Provides Insight into the Role and Regulatory Mechanisms of IL-25 in NK Cells	3
Temperature-Dependent Affinity Changes in Substrate Binding Affect the Cleavage Activity of BthC2c1	3
Kinetic and Thermodynamic Study of Plantaricin IIA-1A5, a Bacteriocin Produced by Indonesian Probiotic Lactobacillus plantarum IIA-1A5	3
Angiotensin-(1-7), Angiotensin-Converting Enzyme 2 and Mas Receptor in Rat Polycystic Ovaries	3
An Inducible Expression System for Recombinant Sca Proteins with an Autotransporter Domain from Orientia Tsutsugamushi in Escherichia coli	3
A Thermostable Aluminum-Tolerant Protease Produced by Feather-Degrading Bacillus thuringiensis Isolated from Tea Plantation	3
Plasma/Serum Proteomics based on Mass Spectrometry	3
Acknowledgement to Reviewers	3
Design, Synthesis and DNA-Binding Activities of GCN4 Peptide Dimer Studied by Circular Dichroism Spectroscopy	3
Purification and Partial Characterization of 5-Oxo-L-Prolinase from Pig Kidney	3
Generation and Characterization of Monoclonal Antibodies Against Tth DNA Polymerase and its Application to Hot-Start PCR	3
The Use of Molecular Docking and Spectroscopic Methods for Investigation of The Interaction Between Regorafenib with Human Serum Albumin (HSA) and Calf Thymus DNA (Ct-DNA) In The Presence Of Different	3
A Novel Brevinin2 HYba5 Peptide against Polymicrobial Biofilm of Staphylococcus aureus and Enterococcus faecalis	3
Polymorphic Variants of ASS1 Gene Related to Arginine Metabolism and the Risk of HCC	3
Angiotensin-(1-7) Improves Islet β-cell Dedifferentiation by Activating PI3K/Akt/FoxO1 Pathway	3
The Application of a Recombinant Antimicrobial Peptide of Thrombocidin-1 Expressed in Pichia pastoris as a Novel Approach Against Some Oral Pathogenic Bacteria: An In Vitro Study	3