OOIR: Observatory of International Research

Papers

(The TQCC of Protein and Peptide Letters is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)

Article	Citations
Characterizing the Binding of Angiotensin Converting Enzyme I Inhibitory Peptide to Human Hemoglobin: Influence of Electromagnetic Fields	42
Renin-Angiotensin System and Alzheimer’s Disease Pathophysiology: From the Potential Interactions to Therapeutic Perspectives	25
Antimicrobial Peptides: An Overview of their Structure, Function and Mechanism of Action	21
Exploring the Evidence Implicating the Renin-Angiotensin System (RAS) in the Physiopathology of Mood Disorders	18
Self-Assembly of Cyclic Dipeptides: Platforms for Functional Materials	18
Liposome Circulation Time is Prolonged by CD47 Coating	17
Predicting Protein Surface Property with its Surface Hydrophobicity	17
Expression, Solubilization, Refolding and Final Purification of Recombinant Proteins as Expressed in the form of “Classical Inclusion Bodies” in E. coli	16
Resveratrol Regulates Nrf2-Mediated Expression of Antioxidant and Xenobiotic Metabolizing Enzymes in Pesticides-Induced Parkinsonism	16
Adipokines: A Rainbow of Proteins with Metabolic and Endocrine Functions	15
The Renin-Angiotensin System and the Cerebrovascular Diseases: Experimental and Clinical Evidence	15
Neuropsychiatric Properties of the ACE2/Ang-(1-7)/Mas Pathway: A Brief Review	14
Discovery of Antioxidant Peptides from Amphibians: A Review	14
Plant Bioactive Peptides: Current Status and Prospects Towards Use on Human Health	13
Cross-talk of Signaling Pathways in the Pathogenesis of Allergic Asthma and Cataract	12
CRISPR-Cas9, A Promising Therapeutic Tool for Cancer Therapy: A Review	12
Quantifying Serum Derived Differential Expressed and Low Molecular Weight Protein in Breast Cancer Patients	11
Diosmetin Induces Apoptosis by Downregulating AKT Phosphorylation via P53 Activation in Human Renal Carcinoma ACHN Cells	11
Anticancer Mechanisms of Bioactive Peptides	11
Binding Sites of Anticancer Drugs on Human Serum Albumin (HSA): A Review	11
Antimicrobial and Antibiofilm Activity of Lys-[Trp6]hy-a1 Combined with Ciprofloxacin Against Gram-Negative Bacteria	10
The Renin Angiotensin System and Bipolar Disorder: A Systematic Review	10
A Comprehensive Guide to the Commercial Baculovirus Expression Vector Systems for Recombinant Protein Production	10
Phosphorylated and O-GlcNAc Modified IRS-1 (Ser1101) and -2 (Ser1149) Contribute to Human Diabetes Type II	9
The Effects of Amoxicillin, Cefazolin, and Gentamicin Antibiotics on the Antioxidant System in Mouse Heart Tissues	9

Stem Bromelain Proteolytic Machinery: Study of the Effects of its Components on Fibrin (ogen) and Blood Coagulation	9
Anticancer Activity of Lectins from Bauhinia purpurea and Wisteria floribunda on Breast Cancer MCF-7 Cell Lines	9
Mechanisms of Lignin-Degrading Enzymes	9
Evolution and Structure of API5 and Its Roles in Anti-Apoptosis	9
Boosting Auto-Induction of Recombinant Proteins in Escherichia coli with Glucose and Lactose Additives	9
Aloperine Induces Apoptosis by a Reactive Oxygen Species Activation Mechanism in Human Ovarian Cancer Cells	9
Deciphering of The Effect of Chemotherapeutic Agents on Human Glutathione S-Transferase Enzyme and MCF-7 Cell Line	8
Biophysical Insight into Protein Folding, Aggregate Formation and its Inhibition Strategies	8
Putative Antimicrobial Peptides in Fish: Using Zebrafish as a Representative	8
Heterologous Expression and Application of Multicopper Oxidases from Enterococcus spp. for Degradation of Biogenic Amines	8
EGLLGDVF: A Novel Peptide from Green Mussel Perna viridis Foot Exerts Stability and Anti-inflammatory Effects on LPS-Stimulated RAW264.7 Cells	8
Rational Design and Intramolecular Cyclization of Hotspot Peptide Segments at YAP–TEAD4 Complex Interface	8
INSL3: A Marker of Leydig Cell Function and Testis-Bone-Skeletal Muscle Network	8
Osteocalcin: A Protein Hormone Connecting Metabolism, Bone and Testis Function	8
Bovine Lactoferrin can Decrease the In Vitro Biofilm Production and Show Synergy with Antibiotics Against Listeria and Escherichia coli Isolates	8
Ribosome Hibernation as a Stress Response of Bacteria	7
Plant Terpenes on Treating Cardiovascular and Metabolic Disease: A Review	7
Allergen Homologues, Pathogenesis-Related 1, Polygalacturonase, and Pectin Methyl Esterase from a Japanese Hop	7
pH-Sensitive Polymer-Based Carriers as a Useful Approach for Oral Delivery of Therapeutic Protein: A Review	7
Investigation of the Role of Aromatic Residues in the Antimicrobial Peptide BuCATHL4B	7
Genome-Wide Association Studies (GWAS) for Traits Related to Fodder Quality and Biofuel in Sorghum: Progress and Prospects	7
Effects of Co-Solvents on Loading and Release Properties of Self- Assembled Di-Peptide Building Blocks, Towards Drug Delivery Applications	7
Bifunctional Inhibitors from Capsicum chinense Seeds with Antimicrobial Activity and Specific Mechanism of Action Against Phytopathogenic Fungi	7
Antinociceptive Effects of VV-Hemorphin-5 Peptide Analogues Containing Amino phosphonate Moiety in Mouse Formalin Model of Pain	7
Review of Evidence and Perspectives of Flavonoids on Metabolic Syndrome and Neurodegenerative Disease	7
Neuropeptide Y Induces Cardiomyocyte Hypertrophy via Attenuating miR-29a-3p in Neonatal Rat Cardiomyocytes	7
Long Non-coding RNA UCA1 Regulates SRPK1 Expression Through miR- 99b-3p in Ovarian Cancer	6
Effect of Isolated Proteins from Crotalus Durissus Terrificus Venom on Leishmania (Leishmania) Amazonensis-Infected Macrophages	6
Phosphoserine Aminotransferase has Conserved Active Site from Microbes to Higher Eukaryotes with Minor Deviations	6
Microbial Cold Shock Proteins: Overview of their Function and Mechanism of Action	6
Isolation and Characterization of CD39-like Phosphodiesterase (Cc-PDE) from Cerastes cerastes Venom: Molecular Inhibitory Mechanism of Antiaggregation and Anticoagulation	6
The Renin-Angiotensin System in Huntington’s Disease: Villain or Hero?	6
Triple-A Syndrome (TAS): An In-Depth Overview on Genetic and Phenotype Heterogeneity	6
Potential Application of CRISPR/Cas9 System to Engineer Abiotic Stress Tolerance in Plants	6
Enhanced Phytase Production by Bacillus subtilis subsp. subtilis in Solid State Fermentation and its Utility in Improving Food Nutrition	6
Serum HSP90-Alpha and Oral Squamous Cell Carcinoma: A Prospective Biomarker	5
Renin-Angiotensin-Aldosterone System and Migraine: A Systematic Review of Human Studies	5
Soluble Diphtheria Toxin Variant, CRM 197 was Obtained in Escherichia coli at High Productivity Using SUMO Fusion and an Adjusted Expression Strategy	5
Current Trends and Applications of Food-derived Antihypertensive Peptides for the Management of Cardiovascular Disease	5
Mesenchymal Stem Cell Derived-Exosomes as Effective Factors in Reducing Cytokine Storm Symptoms of COVID-19	5
Site-Selective, Chemical Modification of Protein at Aromatic Side Chain and Their Emergent Applications	5
Solvent Perturbation of Protein Structures - A Review Study with Lectins	5
Database Study on the Expression and Purification of Membrane Proteins	5
Heterologous Expression and Function of Cholesterol Oxidase: A Review	5
Angiotensin-(1-7), Angiotensin-Converting Enzyme 2 and Mas Receptor in Rat Polycystic Ovaries	5
An Insight into Oligopeptide Transporter 3 (OPT3) Family Proteins	5
Screening of MMP-2 Inhibiting Phytoconstituents for the Development of Newer Pancreatic Cancer Treatment Modalities	5
Fraxin Prevents Knee Osteoarthritis through Inhibiting Chondrocyte Apoptosis in an Experimental Rat Osteoarthritis Model	5
Metabolomics: A Powerful Tool to Study the Complexity of Wheat Metabolome	5
Why Do We Need New Markers for Male Hypogonadism and How Seminal Proteomics Might Solve the Problem?	5

Angiotensin I-Converting Enzyme (ACE-I) Inhibition and Antioxidant Peptide from a Squilla Species	4
Encapsulation of Purified Pediocin of Pediococcus pentosaceus into Liposome Based Nanovesicles and its Antilisterial Effect	4
Interaction of the Seed Lectin from Parkia Platycephala (Mimosoideae) with Carbohydrates and Complex Glycans	4
Acetogenin Extracted from Annona muricata Prevented the Actions of EGF in PA-1 Ovarian Cancer Cells	4
The Role of Growth Hormone Receptor Isoforms and Their Effects in Bone Metabolism and Skeletal Fragility	4
Novel Insights on the Role of the Human Sperm Proteome	4
The Use of Molecular Docking and Spectroscopic Methods for Investigation of The Interaction Between Regorafenib with Human Serum Albumin (HSA) and Calf Thymus DNA (Ct-DNA) In The Presence Of Different	4
Effect of Antioxidants on Heavy Metals Induced Conformational Alteration of Cytochrome C and Myoglobin	4
Evaluation of the In Vivo Acute Toxicity and In Vitro Hemolytic and Immunomodulatory Activities of the Moringa oleifera Flower Trypsin Inhibitor (MoFTI)	4
A Cassava CPRF-2-like bZIP Transcription Factor Showed Increased Transcript Levels during Light Treatment	4
Purification and Characterization of Thermostable α-Amylase from Soil Bacterium Bacillus sp.	4
Genome-Wide Association Study for Major Biofuel Traits in Sorghum Using Minicore Collection	4
Expression of Brazzein, A Small Sweet-Tasting Protein in Saccharomyces cerevisiae: An Introduction for Production of Sweet Yeasts	4
Improved Prediction of Protein-Protein Interaction Mapping on Homo Sapiens by Using Amino Acid Sequence Features in a Supervised Learning Framework	4
An Overview of 7α- and 7β-Hydroxysteroid Dehydrogenases: Structure, Specificity and Practical Application	4
Hydroalcoholic Extract of Solanum lycocarpum A. St. Hil. (Solanaceae) Leaves Improves Alloxan-Induced Diabetes Complications in Mice	4
Repeated Administration of Orexin into the Thalamic Paraventricular Nucleus Inhibits the Development of Morphine-Induced Analgesia	4
Separation of the Epitopes in a Multi-Epitope Chimera: Helical or Flexible Linkers	4
Some Minor Characteristics of Spectrophotometric Determination of Antioxidant System and Phenolic Metabolism Enzyme Activity in Wood Plant Tissues of Pinus sylvestris L.	4
The Proteins Interacting with Prmt5 in Medaka (Oryzias latipes) Identified by Yeast Two-Hybridization	4
Increased Expression of Recombinant Chitosanase by Co-expression of Hac1p in the Yeast Pichia pastoris	4
In Vitro Evaluation of Immunogenicity of Recombinant OMP25 Protein Obtained from Endemic Brucella abortus Biovar 3 as Vaccine Candidate Molecule Against Animal Brucellosis	4
Pathways Related to the Anti-Cancer Effects of Metabolites Derived from Cerrado Biome Native Plants: An Update and Bioinformatics Analysis on Oral Squamous Cell Carcinoma	4
Molecular Insights into Zn2+ Inhibition of the Antibacterial Endopeptidase Lysostaphin from Staphylococcus simulans	4
Protein Markers in Osteoporosis	4
Variable Length Character N-Gram Embedding of Protein Sequences for Secondary Structure Prediction	4
HIV-1 Accessory Proteins: Which one is Potentially Effective in Diagnosis and Vaccine Development?	4
Interaction of Human Alpha-2-Macroglobulin with Pesticide Aldicarb Using Spectroscopy and Molecular Docking	4
Porcine Epidemic Diarrhea: Causative Agent, Epidemiology, Clinical Characteristics, and Treatment Strategy Targeting Main Protease	4
Antagonistic Effect of Truncated Fragments of Bacillus thuringiensis Vip3Aa on the Larvicidal Activity of its Full-length Protein	4
Studies on Molecular Interactions between Bovine β-Lactoglobulin and Silver Nanoparticles	4
Prospecting Potential Inhibitors of Sortase A from Enterococcus faecalis: A Multidrug Resistant Bacteria, through In-silico and In-vitro Approaches	4
Matrix Metalloproteinases in Invertebrates	4
Purification of Classical Swine Fever Virus E2 Subunit Vaccines Based on High Affinity Peptide Ligand	4
Oral Angiotensin-(1-7) Peptide Modulates Intestinal Microbiota Improving Metabolic Profile in Obese Mice	4
Stepwise Development of Biomimetic Chimeric Peptides for Gene Delivery	3
Novel Post-translational Modifications in Human Serum Albumin	3
Renin-Angiotensin System: Role in Cerebrovascular, Neurodegenerative and Psychiatric Disease	3
Structural Analysis Revealed the Interaction of Cardenolides from Calotropis procera with Na+/K+ ATPases from Herbivores	3
Lactococcus lactis and Resveratrol Decrease Body Weight and Increase Benefic Gastrointestinal Microbiota in Mice	3
Research Progress of the UPR Mechanism and its Effect on Improving Foreign Protein Expression	3
Expression, Rapid Purification and Functional Analysis of DnaK from Rhodococcus ruber	3
Tannic Acid Exhibits Adjuvant Activity by Enhancing Humoral and Cell-Mediated Immunity Against BSA as a Protein Antigen	3
Directive Effect of Chain Length in Modulating Peptide Nano-assemblies	3
DeepSSPred: A Deep Learning Based Sulfenylation Site Predictor Via a Novel nSegmented Optimize Federated Feature Encoder	3
Biological Sensing and Imaging Using Conjugated Polymers and Peptide Substrates	3
Purification, Partial Characterization, and Evaluation of the Antiulcer Activity of Calotropis procera Leaf Lectin	3
Effective Delivery of Nef-MPER-V3 Fusion Protein Using LDP12 Cell Penetrating Peptide for Development of Preventive/Therapeutic HIV-1 Vaccine	3
Development of Cell Penetrating Peptides for Effective Delivery of Recombinant Factors into Target Cells	3
Study on the Mechanism of Selective Interaction of BR3 and BCMA with BAFF and APRIL	3
Establishment of Method for the Determination of Aggregated α-Synuclein in DLB Patient Using RT-QuIC Assay	3
Preparation of IgE Antibody and Distribution of IgE+ Secretory Cells in the Palatine Tonsil of Bactrian Camel	3
Hepatotoxic Effect of Lafoensia pacari A. St. Hil. (Lythraceae) on a Diet-Induced Obese Mice Model	3
Identification of Salmonella Typhimurium Peptidyl-prolyl cis-trans Isomerase B (PPIase B) and Assessment of their Role in the Protein Folding	3
Proteomic analysis of a hom-disrupted, cephamycin C overproducing Streptomyces clavuligerus	3
Proteomics-Based Characterization of the Effects of MMP14 on the Protein Content of Exosomes from Corneal Fibroblasts	3
Spider Silks: An Overview of Their Component Proteins for Hydrophobicity and Biomedical Applications	3
Non-Enzymatic Protein Acetylation by 7-Acetoxy-4-Methylcoumarin: Implications in Protein Biochemistry	3
Expression and Purification of Tetanus Toxin Fragment C in Escherichia coli BL21(DE3)	3
Prediction of Variable-Length B-Cell Epitopes for Antipeptide Paratopes Using the Program HAPTIC	3
A Flounder Fish Peptide Shows Anti-Hypertensive Effects by Suppressing the Renin-Angiotensin-Aldosterone System and Endothelin-1	3
Human Serum Albumin Aggregation and its Modulation Using Nanoparticles: A Review	3
Characterization and Expression Analysis of Resistance Gene Analogues in Elite Sugarcane Genotypes	3
Utilization of SUMO Tag and Freeze-thawing Method for a High-level Expression and Solubilization of Recombinant Human Angiotensinconverting Enzyme 2 (rhACE2) Protein in E. coli	3
Cloning, Prokaryotic Expression, and Purification of Acetyl-CoA C-Acetyltransferase from Atractylodes lancea	3
Beyond B-Cell Epitopes: Curating Positive Data on Antipeptide Paratope Binding to Support Peptide-Based Vaccine Design	3
Porphyromonas gingivalis Lipopolysaccharide-Induced B Cell Differentiation by Toll-like Receptors 2 and 4	3
Modified Levels of Renin Angiotensin Related Components in the Frontal Cortex and Hippocampus were Associated with Neuroinflammation and Lower Neuroprotective Effects of NGF During Acute Hepatic Encep	3
Cloning, Expression, and Functional Analysis of the Full-Length cDNA of Acetyl-CoA C-acetyltransferase (AACT) Genes Related to Terpenoid Synthesis in Platycodon grandiflorus	3
Expression Analysis of Lanosterol Synthase Gene in Dynamic Accumulation of Triterpenoids in Sanghuangporus baumii	3
Characterization of Three Osmotin-Like Proteins from Plumeria rubra and Prospection for Adiponectin Peptidomimetics	3
Effect of Disease Causing Missense Mutations on Intrinsically Disordered Regions in Proteins	3
Protein Tyrosine Phosphatase Receptor-type Q: Structure, Activity, and Implications in Human Disease	3
SynB3 Conjugated QBP1 Passes Blood-Brain Barrier Models and Inhibits PolyQ Protein Aggregation	3