OOIR: Observatory of International Research

Papers

(The TQCC of Protein and Peptide Letters is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
FOXN3 Expression Regulated by miR-299-5p Inhibiting the Proliferation, Migration and Invasion of Oral Squamous Cell Carcinoma Cells	50
The Sensitive Genes in Response to Various Metal Ion Stresses in the Yeast Saccharomyces cerevisiae	37
Amplification of Amyloid Protein-induced Aggregation of the Eukaryotic Ribosome	26
Heat-Shock Triggers Inverted Induction of Hypo-S-Nitrosylation and Hyper-O-GlcNAcylation	25
Effects of Glutathionylation on Guanylyltransferase Activity of NS5 N-terminal Capping Domain from Dengue, Japanese Encephalitis, and Zika Viruses	19
Water-soluble Moringa oleifera Seed Lectin Exhibits Monoaminergic Pathway-linked Anti-depressive-like Effects in Mice	14
Structural Shifts of the Parvovirus B19 Capsid Receptor-binding Domain: A Peptide Study	14
Molecular Interactions of the Antimicrobial Peptide Tritrpticin with Mixed Nanoaggregates: A Fluorescence Spectroscopy Study	12
Understanding Protein Functions in the Biological Context	12
Beyond B-Cell Epitopes: Curating Positive Data on Antipeptide Paratope Binding to Support Peptide-Based Vaccine Design	12
Genome-Wide Association Studies (GWAS) for Traits Related to Fodder Quality and Biofuel in Sorghum: Progress and Prospects	11
An Overview of the Role of Membrane Proteins in Microbial Solvents Tolerance	11
Effect of Adipokinetic Hormone on Learning-Memory in a Scopolamine-Induced Alzheimer's Model in Mice	11
Inhibition of Canonical Wnt Signaling in Renal Cell Carcinoma Bone Metastasis: An Immunohistochemical Analysis of DKK1 and LRP5 Expression	10
Plasma/Serum Proteomics based on Mass Spectrometry	10
ZP3 Expression in Pancreatic Adenocarcinoma: Its Implications for the Prognosis and Therapy	9
Construction and Evaluation of Recombinant Chimeric Fibrillin and Elastin Fragment in Human Mesenchymal Stem Cells	9
The Application of a Recombinant Antimicrobial Peptide of Thrombocidin-1 Expressed in Pichia pastoris as a Novel Approach Against Some Oral Pathogenic Bacteria: An In Vitro Study	9
LINC01836 Promotes Colorectal Cancer Progression and Functions as ceRNA to Target SLC17A9 by Sponging miR-1226-3p	9
Current Trends and Applications of Food-derived Antihypertensive Peptides for the Management of Cardiovascular Disease	9
Increased Expression of Recombinant Chitosanase by Co-expression of Hac1p in the Yeast Pichia pastoris	9
HSP90-regulated CHIP/TRIM21/p21 Axis Involves in the Senescence of Osteosarcoma Cells	9
The Implication of Hypocretin in Drug Abuse and Arousal in the Brain Stem	9
Molecular Bases of Protein Antigenicity and Determinants of Immunogenicity, Anergy, and Mitogenicity	8
Association between Higher Expression of Vav1 in Hepatocellular Carcinoma and Unfavourable Clinicopathological Features and Prognosis	8

SNHG3/miR-330-5p/HSD11B1 Alleviates Myocardial Ischemia-reperfusion Injury by Regulating the ERK/p38 Signaling Pathway	8
Variable Surface Antigens of Plasmodium falciparum: Protein Families with Divergent Roles	8
Trypsin/α-Amylase Inhibitors from Capsicum chinense Seeds: Characterization and Antifungal Activity against Fungi of Agronomic Importance	8
Protein Tyrosine Phosphatase Receptor-type Q: Structure, Activity, and Implications in Human Disease	8
A Review of Gap Junction Protein and its Potential Role in Nervous System-Related Disease	8
Investigation of Early Growth Response Protein (EGR) Levels in Patients with Fibromyalgia Syndrome: A Cross-Sectional Study	7
Unveiling the Molecular Mechanism of Diosmetin and its Impact on Multifaceted Cellular Signaling Pathways	7
Neuropeptide Network of Polycystic Ovary Syndrome – A Review	7
Unraveling the Role of Functional Amyloids and Amyloid Peptides in Disease Detection	7
Comprehensive Analysis of lncRNA and mRNA Expression Profile of Macrophage RAW264.7 Stimulated by Antimicrobial Peptide BSN-37	7
Improved Soluble Expression in Escherichia coli and Easily Purified Recombinant Human Bone Morphogenetic 7-2 Fusion Protein	7
Targeting APE1: Advancements in the Diagnosis and Treatment of Tumors	7
Human Serum Albumin Aggregation and its Modulation Using Nanoparticles: A Review	7
Binding of l-Anilino-8-Napthalenesulfonate to Free and Coformycin-Complexed Bovine Adenosine Deaminase	7
Synthesis of Two Designed Hairprin Peptides on a Newly Developed 1,6-Hexanediol Diacrylate (HDODA)-Crosslinked Polystyrene Resin	7
Potassium Channels Contributes to Apelin-induced Vasodilation in Rat Thoracic Aorta	7
UPBEAT1-ROS-POD-PAL System under Different Xylogenesis Scenarios in Karelian Birch (Betula pendula Roth var. carelica (Mercl.) Hämet-Ahti)	6
Dexmedetomidine Alleviates Brain Ischemia/Reperfusion Injury by Regulating Metastasis-associated Lung Adenocarcinoma Transcript 1/MicroRNA-140-5p/ Nuclear Factor Erythroid-derived 2-like 2 Axis	6
Regulatory Mechanism of lncRNA CTBP1-AS2 in Nasopharyngeal Carcinoma Cell Proliferation and Apoptosis via the miR-140-5p/BMP2 Axis	6
P53-induced GAP-43 Upregulation in Primary Cortical Neurons of Rats	6
Oral Angiotensin-(1-7) Peptide Modulates Intestinal Microbiota Improving Metabolic Profile in Obese Mice	6
Neuroprotective Effect of Dexmedetomidine Pretreatment on Sevoflurane- Initiated Neurotoxicity Via the Mir-204-5p/SOX4 Axis	6
Database Study on the Expression and Purification of Membrane Proteins	6
Thermodynamics of the Association of Aminoglycoside Antibiotics with Human Angiogenin	6
Gelsolin Inhibits the Proliferation of Colon Cancer Cells by Enhancing the Expression of TNFR2/CASP10 as a Death Receptor Pathway	6
Guanidinium-based Integrated Peptide Dendrimers: Pioneer Nanocarrier in Cancer Therapy	6
A Review on Recent Advancement in Expression Strategies Used in Bacillus subtilis	6
Knockdown of Programmed Death 1 Inhibited Progression of Papillary Thyroid Carcinoma in Mice	6
Preface	6
Identifying the Role of Individual Seal IAPP Amino Acids in Inhibiting the Aggregation of Human IAPP	5
Structural and Functional Analysis of Urease Accessory Protein E from Vancomycin-Resistance Staphylococcus aureus MU50 Strain	5
Insights into Coronavirus Papain-like Protease Structure, Function and Inhibitors	5
Feasibility of Domain Segmentation of B19V VP1u Using Intein Technology for Structural Studies	5
Design of Artificial C-Peptides as Potential Anti-HIV-1 Inhibitors Based on 6-HB Formation Mechanism	5
Insights into the Dynamic Fluctuations of the Protein HPV16 E1 and Identification of Motifs by Using Elastic Network Modeling	5
Meclofenoxate Inhibits Aggregation of Alpha-synuclein in vitro	5
Wogonin Restrains the Malignant Progression of Lung Cancer Through Modulating MMP1 and PI3K/AKT Signaling Pathway	5
Screening of MMP-2 Inhibiting Phytoconstituents for the Development of Newer Pancreatic Cancer Treatment Modalities	5
Modified Levels of Renin Angiotensin Related Components in the Frontal Cortex and Hippocampus were Associated with Neuroinflammation and Lower Neuroprotective Effects of NGF During Acute Hepatic Encep	5
Unidentified N-glycans by N-glycosidase A were Identified by Nglycosidase F under Denaturing Conditions in Plant Glycoprotein	5
Comparison of Adjuvant Effects of Montanide ISA-720 and Heat Shock Protein 27 in Increasing Immunostimulatory Properties of HIV-1 Nef-Vif Fusion Protein Construct	5
Effect of Propeptide Mutations on the Directed Evolution of Rhizomucor miehei Lipase	5
Cold-Induced RNA-Binding Protein and RNA-Binding Motif Protein 3: Two RNA Molecular Chaperones Closely Related to Reproductive Development and Reproductive System Diseases	5
Methods of PARP-1 Determination and its Importance in Living Organisms	5
Lessons Learnt and the Way Forward for Drug Development Against Isocitrate Lyase from Mycobacterium tuberculosis	5
Preparation of IgE Antibody and Distribution of IgE+ Secretory Cells in the Palatine Tonsil of Bactrian Camel	5
The LL-37 Antimicrobial Peptide as a Treatment for Systematic Infection of Acinetobacter baumannii in a Mouse Model	5
Expression and Purification of His-Tagged Variants of Human Hepatitis A Virus 3C Protease	5
Applications of Plant Proteinase Inhibitors in Agriculture	5
Development of a Peptide-Based Multiepitope Vaccine from the SARS-CoV-2 Spike Protein for Targeted Immune Response Against COVID-19	4

Structural Analysis Revealed the Interaction of Cardenolides from Calotropis procera with Na+/K+ ATPases from Herbivores	4
Preface	4
Concentration-mediated Folding and Unfolding of Collagen Triple Helix	4
Proteomic Analysis of Glucose-Induced Cardiac Myoblasts and the Potential Role of mir-92b-5p in Regulating Sarcomere Proteins Under a Hyperglycemic Environment	4
Anticancer and Antimicrobial Evaluations on Alternative Reading Frame (ARF) Peptides and their Derivatives	4
The Agonistic Activity of the Human Epidermal Growth Factor is Reduced by the D46G Substitution	4
Combining Network Pharmacology, Molecular Docking and Preliminary Experiments to Explore the Mechanism of Action of FZKA Formula on Non-small Cell Lung Cancer	4
Applications of CRISPR Cas-9 in Ovarian Cancer Research	4
Plastid Transcriptomics: An Important Tool For Plastid Functional Genomics	4
In Silico Analysis of Natural Plant-Derived Cyclotides with Antifungal Activity against Pathogenic Fungi	4
Proteomic Analysis of the Colistin-resistant E. coli Clinical Isolate: Explorations of the Resistome	4
Nonhuman IAPP Variants Inhibit Human IAPP Aggregation	4
Graphenoxide Cross-Linker Based Potentiometric Biosensor Design for Sarcosine Determination	4
Disruption of Staphylococcus aureus Biofilms with Purified Moringa oleifera Leaf Extract Protein	4
Some Minor Characteristics of Spectrophotometric Determination of Antioxidant System and Phenolic Metabolism Enzyme Activity in Wood Plant Tissues of Pinus sylvestris L.	4
Antimicrobial Peptides: An Overview of their Structure, Function and Mechanism of Action	4
Characterization of a Novel Thermostable 7α-Hydroxysteroid Dehydrogenase	4
Purification, Crystallization, and Preliminary X-Ray Diffraction Studies on Hemoglobin from the Angora Goat (Capra Aegagrus Hircus)	4
Mesenchymal Stem Cell Derived-Exosomes as Effective Factors in Reducing Cytokine Storm Symptoms of COVID-19	4
The Roles of Ciliary Neurotrophic Factor - from Neuronutrition to Energy Metabolism	4
Interaction of the Seed Lectin from Parkia Platycephala (Mimosoideae) with Carbohydrates and Complex Glycans	4
Strategy for the Enrichment of Protein Biomarkers from Diverse Bacterial Select Agents	4
Natural Amphibian-Derived Host Defense Peptides: Peptide Immunomodulators with Potential Therapeutic Value	4
Design, Synthesis and DNA-Binding Activities of GCN4 Peptide Dimer Studied by Circular Dichroism Spectroscopy	4
A Functional Human Glycogen Debranching Enzyme Encoded by a Synthetic Gene: Its Implications for Glycogen Storage Disease Type III Management	4
Participation of CWINV and SUS Genes in Sucrose Utilization in the Disruption of Cambium Derivatives Differentiation of Silver Birch	3
Analysis of the Interaction of UBE2Q1 with B4GALT1 and P53: Experimental and Molecular Modeling Study	3
Process Development for the Production and Purification of PEGylated RhG-CSF Expressed in Escherichia coli	3
Structural Phylogeny of Different Allergens May Reveal Common Epitopic Footprint	3
Mimicking LysC Proteolysis by ‘Arginine Modification-cum-Trypsin Digestion’: Comparison of Bottom-up & Middle-down Proteomic Approaches by ESI Q-TOF MS	3
Study on the Analgesic Activity of Peptide from Conus achates	3
Design, Expression, and Purification of a Fusion Enzyme Containing Terminal Deoxynucleotidyl Transferase from B. bovis and DNA-Binding Proteins from E. coli	3
Exploring the Potential Long-term Impact of SARS-CoV-2 on Protein Misfolding and Amyloid-related Conditions	3
Circ_0008768 Suppresses the Pancreatic Cancer Progression via miR-330- 3p/PTEN Axis	3
MicroRNA-605-3p Inhibited the Growth and Chemoresistance of Osteosarcoma Cells via Negatively Modulating RAF1	3
Cyclopeptide-based Anti-liver Cancer Agents: A Mini-review	3
Overview of Lignocellulolytic Enzyme Systems with Special Reference to Valorization of Lignocellulosic Biomass	3
Interaction of Synthetic Pyrethroid Insecticide Deltamethrin with Human Alpha-2-Macroglobulin: Spectroscopic and Molecular Docking Studies	3
Circ_0006789 Promotes the Progression of Hepatocellular Carcinoma Cells via Modulating miR-1324 and SOX12	3
Antioxidant Responses are Crucial for Defense against Misfolded Human Z-Type α₁-Antitrypsin	3
The Role of TGFBR3 in the Development of Lung Cancer	3
Antimicrobial Activity of a Defensin-Rich Fraction from Capsicum Chinense Fruits: Insights for Biotechnological Applications against Fungal Infections	3
Exploring the Cell Wall and Secretory Proteins of Mycobacterium leprae as Biomarkers	3
Estrogen Sulfotransferase SULT1E1 Expression Levels and Regulated Factors in Malignant Tumours	3
Expression, Purification, and Evaluation of Antibody Responses and Antibody-Immunogen Complex Simulation of a Designed Multi-Epitope Vaccine against SARS-COV-2	3
Biophysical Insight into Protein Folding, Aggregate Formation and its Inhibition Strategies	3
Production of Soluble Murine TRAILs in Escherichia coli with Zn²⁺ Supplementation	3
Biochemical Aspects of the Spiral Grain Formation in Scots Pine (Pinus Sylvestris L.) Wood. Some Differences and Similarities with Biochemical Indicators of Abnormal Xylogenesis in Karelian Birch (Bet	3
Unlocking the Keratinolytic Potential of Brevibacillusagri Derived Keratinase: A Molecular Characterization Study	3
Corrigendum to: Investigation of the Expression and Regulation of SCG5 in the Context of the Chromogranin-Secretogranin Family in Malignant Tumors	3
Structure of Cadmiull}-Substituted Phospholipase A2 from Agkistrodon halys Pallas at 2.8A Resolution	3
Development of an Autoinducible Plasmid for Recombinant Protein Production	3
Protein Arginine Methyltransferase 1 and its Dynamic Regulation Associated with Cellular Processes and Diseases	3
Boosting Auto-Induction of Recombinant Proteins in Escherichia coli with Glucose and Lactose Additives	3
Optimizing Sleep in Athletes: The Potential of α-Lactalbumin in Nutrition Intervention	3