OOIR: Observatory of International Research

Papers

(The H4-Index of Current Medicinal Chemistry is 33. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Drug-target Affinity Prediction by Molecule Secondary Structure Representation Network	197
Natural Herbal Compounds Exerting an Antidepressant Effect through Hypothalamic-Pituitary-Adrenal Axis Regulation	121
Meet Our Editorial Board Member	74
SGPocket: A New Graph Convolutional Neural Network for Ligand-protein Binding Site Prediction	72
The [18F] F-PSMA Probe: Chemical Perspectives	71
Elemene Injection Suppresses Pancreatic Cancer Progress through Regulating Cell Adhesion: A Research Based upon Network Pharmacology and Verification Test	68
Oridonin Suppresses the Malignant Progression of Lung Cancer by Targeting S100A11	67
Amide Derivative of Arjunolic Acid TA-1,4-BiP Enhances ROSmediated Apoptosis in Colorectal Cancer Cells	60
COVID-19―Where Are We Now	52
Costimulation Blockade Resistant Rejection	51
Meet the Editorial Board Member	51
Expression of Circulating miR-21 and -29 and their Association with Myocardial Fibrosis in Hypertrophic Cardiomyopathy	50
The Effects of Statin Therapy on Circulating Levels of Trimethylamine N-oxide: A Systematic Review and Meta-analysis	49
An Updated Review Deciphering Apigenin Nanostructures as Promising Therapeutic Efficiency in Human Carcinomas	48
New Small-molecule Analgesics	47
Integrated Exploration of Pyranocoumarin Derivatives as Synergistic Inhibitors of Dual-target for Mpro and PLpro Proteins of SARS-CoV-2 through Molecular Docking, ADMET Analysis, and Molecular Dynamic	47
Medicinal (Radio) Chemistry: Building Radiopharmaceuticals for the Future	46
Therapeutic Effect of Rosolic Acid against Endothelial Dysfunction in Diabetic Wistar Rats	45
Circ_0079471 Regulates the Proliferation, Migration, Invasion and Apoptosis of Osteosarcoma Cells by Mediating miR-485-3p and TRIP6	42
Design of PI3K-mTOR Dual Inhibitors for Ovarian Cancer: Are we on the Right Track?	42
Identification and Verification of Metabolism-related Immunotherapy Features and Prognosis in Lung Adenocarcinoma	40
Unraveling the Ferroptosis-inducing Potential of Methanol Leaves Extract of Prosopis Juliflora Via Downregulation of SLC7A11 and GPX4 mRNA Expression in A549 Lung Cancer Cells	40
Meet the Editorial Board Member	40
Bacillus sp. Bacteriocins: Natural Weapons against Bacterial Enemies	39
Computer-Aided Drug Design of Anti-inflammatory Agents Targeting Microsomal Prostaglandin E₂Synthase-1 (mPGES-1)	38

First Approval of Adagrasib for the Treatment of Non-Small Cell Lung Cancer Harboring a KRASG12C Mutation	37
Competence Regulation in Streptococcus pneumoniae and the Competence-targeted Anti-pneumococcal Strategies	36
New Insights into the Long Non-coding RNAs Dependent Modulation of Heart Failure and Cardiac Hypertrophy: From Molecular Function to Diagnosis and Treatment	36
Molecular Mechanism of the Canonical Oncogenic lncRNA MALAT1 in Gastric Cancer	36
Artificial Intelligence for Epigenetics: Towards Personalized Medicine	36
A Novel Approach for Designing Electrochemical Aptamer-Based Biosensor for Ultrasensitive Detection of Zearalenone as a Prevalent Estrogenic Mycotoxin	35
TESMIN is a Prognostic Biomarker Associated with Immunosuppression and Activated Cell Cycle in Lung Adenocarcinoma	35
Meet the Editorial Board Member	34
An Updated Review on the Therapeutic, Diagnostic, and Prognostic Value of Long Non-Coding RNAs in Gastric Cancer	33
Preface	33