OOIR: Observatory of International Research

Papers

(The H4-Index of Current Medicinal Chemistry is 35. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)

Article	Citations
SARS-CoV-2: Recent Reports on Antiviral Therapies Based on Lopinavir/Ritonavir, Darunavir/Umifenovir, Hydroxychloroquine, Remdesivir, Favipiravir and other Drugs for the Treatment of the New Coronavir	215
Metal-Organic Framework (MOF)-Based Drug Delivery	162
Recent Research on Flavonoids and their Biomedical Applications	129
Zeolitic Imidazolate Frameworks (ZIF-8) for Biomedical Applications: A Review	129
Antimicrobial Capacity of Plant Polyphenols against Gram-positive Bacteria: A Comprehensive Review	109
Osteoporosis: Mechanism, Molecular Target and Current Status on Drug Development	101
Comprehensive Review on Graphene Oxide for Use in Drug Delivery System	91
Recent Progress in Histone Deacetylase Inhibitors as Anticancer Agents	83
The Role of Zinc and Copper in Insulin Resistance and Diabetes Mellitus	79
Natural Polymer-based Stimuli-responsive Hydrogels	78
Acyclovir in the Treatment of Herpes Viruses – A Review	75
The Role of Diet Related Short-Chain Fatty Acids in Colorectal Cancer Metabolism and Survival: Prevention and Therapeutic Implications	72
Ferroptosis: A Novel Mechanism of Artemisinin and its Derivatives in Cancer Therapy	66
The Application of Hydrogels Based on Natural Polymers for Tissue Engineering	58
The Role of Tumor Associated Macrophages (TAMs) in Cancer Progression, Chemoresistance, Angiogenesis and Metastasis - Current Status	57
Natural Polymers Based Hydrogels for Cell Culture Applications	55
The “Big Five” Phytochemicals Targeting Cancer Stem Cells: Curcumin, EGCG, Sulforaphane, Resveratrol and Genistein	55
Targeting n-3 Polyunsaturated Fatty Acids in Non-Alcoholic Fatty Liver Disease	52
Cyclosporine A: Chemistry and Toxicity – A Review	51
Advances in Pharmacological Activities and Mechanisms of Glycyrrhizic Acid	50
Natural COX-2 Inhibitors as Promising Anti-inflammatory Agents: An Update	49
FTY720 (Fingolimod) Ameliorates Brain Injury through Multiple Mechanisms and is a Strong Candidate for Stroke Treatment	49
B7-H3 Immune Checkpoint Protein in Human Cancer	49
Deep Learning in Drug Target Interaction Prediction: Current and Future Perspectives	46
A Comprehensive Review on Oxysterols and Related Diseases	46

Exosomes and Lung Cancer: Roles in Pathophysiology, Diagnosis and Therapeutic Applications	46
Anti-Coronavirus Vaccines: Past Investigations on SARS-CoV-1 and MERS-CoV, the Approved Vaccines from BioNTech/Pfizer, Moderna, Oxford/AstraZeneca and others under Development Against SARSCoV- 2 Infec	45
Anti-tumor Effects of Curcuminoids in Glioblastoma Multiforme: An Updated Literature Review	44
Osteoporosis: Current and Emerging Therapies Targeted to Immunological Checkpoints	44
Central Regulatory Role of Cytokines in Periodontitis and Targeting Options	43
Obesity and Insulin Resistance: Associations with Chronic Inflammation, Genetic and Epigenetic Factors	42
Recent Progress of Benzimidazole Hybrids for Anticancer Potential	41
Structural Basis of Drug Recognition by Human Serum Albumin	40
Terpenes, Phenylpropanoids, Sulfur and Other Essential Oil Constituents as Inhibitors of Cholinesterases	39
Metal Toxicity and Speciation: A Review	39
Indole Derivatives as Anti-Tubercular Agents: An Overview on their Synthesis and Biological Activities	35
Nanoparticles in Combating Cancer: Opportunities and Limitations: A Brief Review	35