Mammalian Genome

Article	Citations
Primary biliary cirrhosis and rheumatoid arthritis: a comprehensive study combining genetics and transcriptomics	63
Unraveling the maternal heritage: identifying the complex origins of indigenous Indian horse and pony breeds through mitochondrial genome analysis	28
Glycosylated protein-related microenvironmental features in breast cancer are associated with patient prognosis	27
Cancer-associated TRF1 mutations alter PARP1 interaction dynamics: an in silico study	24
Polymorphisms in IRF3 exon 1 influence the immune response to Brucella infection in small ruminants	21
Genetic and immune landscape of keratoconus: insights from Mendelian randomization analysis	20
CPNE1 modulates Parkinson’s disease risk through peripheral immune cell function: a cross-tissue and single-cell causal inference study	19
Evaluation of genotype imputation using Glimpse tools on low coverage ancient DNA	16
Comprehensive analysis reveals the prognostic and immunological role of PSMD13 in hepatocellular carcinoma	16
Contrasting the genetic architecture of cardiac glutathione against other organs: unveiling a unique tissue-specific locus	16
Elucidating the therapeutic targets and multi-target mechanisms of salvianolic acid A for diabetic nephropathy	16
Detection of a complex chromosomal rearrangement in a novel mouse mutant by optical genome mapping	16
Standardisation and future of preclinical echocardiography	15
Climate resilience in goats: a comprehensive review of the genetic basis for adaptation to varied climatic conditions	15
Genome-wide in-silico identification and characterization of LTR retrotransposons in domestic goat (Capra hircus)	14
Comparative single-cell analysis of the adult heart and coronary vasculature	14
Identification of shared hub genes CTNNB1, TJP1, PTK2, and TP53 associated with endothelial proliferation in infantile hemangioma and glioblastoma	13
Introduction to Mammalian Genome special issue: cardiovascular disease in the Mammalian Genome.	13
Evaluation of genomic breeding values and accuracy for carcass traits in Korean Hanwoo cows using whole-genome SNP chip panels	12
Review on camel genetic diversity: ecological and economic perspectives	12
AgAnimalGenomes: browsers for viewing and manually annotating farm animal genomes	11
Impaired immune metabolism in COPD driven by dysfunction of CXCL16 + alveolar macrophages: multivariate causal evidence	11
E2F2 inhibits hippocampal neurogenesis in poststroke depression rats via the miR-1290/CBR1 axis	11
Copy number evolution of conserved noncoding RNA gene families across mammals	11
EEF1A2 identified as a hub gene associated with the severity of metabolic dysfunction-associated steatotic liver disease	11

Integrative immunogenomic and experimental characterization reveals CXCL9, CXCL13, CCL5 and CD74 as key oncogenic drivers in breast cancer	11
IMPC impact on preclinical mouse models	10
Neurodevelopment as a shared genetic etiology linking sleep-related phenotypes and psychiatric disorders: a genome-wide pleiotropic analysis	10
Alpha-synuclein pathology and Parkinson’s disease-related olfactory dysfunctions: an update on preclinical models and therapeutic approaches	9
Neonatal lethality of mouse A/J-7SM consomic strain is caused by an insertion mutation in the Dchs1 gene	9
Are we fully exploiting genetic discoveries to understand and treat Alzheimer’s disease?	9
Generation of a humanized mAce2 and a conditional hACE2 mouse models permissive to SARS-COV-2 infection	9
Cell-type-specific causal effects of CEBPD in CD8 + S100B + Tcells and ZFP36 in monocytes modulate the protective and risk phenotypes in psoriasis	8
TCR CDR3 chemical complementarity to HPV epitopes is associated with a better outcome for cervical cancer	8
Elucidation of genetic determinants of dyslipidaemia using a global screening array for the early detection of coronary artery disease	8
Transforming beef quality through healthy breeding: a strategy to reduce carcinogenic compounds and enhance human health: a review	8
Commentary: towards a national research infrastructure strategy for preclinical biological models in Australia	8
Exploring the molecular function of LYPD3 from pan-cancer to lung cancer: based on bioinformatics and cellular experiments	8
Genome-wide SNP evidence for the genetic uniqueness of indigenous cattle population	8
Genetic insights into crossbred dairy cattle of Pakistan: exploring allele frequency, linkage disequilibrium, and effective population size at a genome-wide scale	8
Comprehensive overview of disease models for Wolfram syndrome: toward effective treatments	8
Knockdown of SOX4 attenuates sepsis myocardial injury by inhibiting the EZH2/H3K27me3/SOCS3 axis	8
Multi-omics dissection of RAD21-PON1 axis reveals metabolic-immune crosstalk and prognostic significance in hepatocellular carcinoma	8
The mouse resource at National Resource Center for Mutant Mice of China	8
Harmonizing mouse anatomy terminology: a common language?	7
Long-read whole-genome sequencing of SHR rat substrains with distinct substance use phenotypes	7
Predicting the potential deterioration of Barrett’s esophagus based on gut microbiota: a Mendelian randomization analysis	7
Comparative genomic studies on the TGF-β superfamily in blue whale	7
Exploration of shared diagnostic genes and mechanisms between crohn’s disease and ischemic stroke by integrated comprehensive bioinformatics analysis and machine learning	7
A fascination with tailless mice: a scientific historical review of studies of the T/t complex	7
A consensus score to combine inferences from multiple centres	7
Maternal genetic diversity and phylogenetic analysis of Indian riverine and swamp buffaloes: insights from complete mitochondrial genomes	7
Insights from homozygous signatures of cervus nippon revealed genetic architecture for components of fitness	7
Purebred dogs show higher levels of genomic damage compared to mixed breed dogs	7
Alantolactone curbs the malignant progression of bladder cancer partly via the HSP90AB1/LRP5/β-catenin axis	6
Identification of EXO1 as a potential biomarker associated with prognosis and tumor immune microenvironment for specific human cancers	6
E3 ubiquitin ligase COP1-mediated CEBPB ubiquitination regulates the inflammatory response of macrophages in sepsis-induced myocardial injury	6
Comprehensive analysis of chromosomal breakpoints and candidate genes associated with male infertility: insights from cytogenetic studies and expression analyses	6
Tachol1 QTL on mouse chromosome 1 is responsible for hypercholesterolemia and diet-induced obesity	6
Dynamics and regulatory role of 5-methylcytosine modification in mRNA colocalized with RNA G-quadruplex structure in mouse development	6
Three-dimensional microCT imaging of mouse heart development from early post-implantation to late fetal stages	6
Arginine attenuates chronic mountain sickness in rats via microRNA-144-5p	6
The mutant mouse resource and research center (MMRRC) consortium: the US-based public mouse repository system	6
Genome-wide study for signatures of selection identifies genomic regions and candidate genes associated with milk traits in sheep	6
Challenges of modelling TDP-43 pathology in mice	5
Genome engineering with Cas9 and AAV repair templates, successes and pitfalls	5
Elucidation of population stratifying markers and selective sweeps in crossbred Landlly pig population using genome-wide SNP data	5
Swine global genomic resources: insights into wild and domesticated populations	5
MicroRNA dysregulation in male infertility: Insights into mechanisms, biomarkers, and therapeutic strategies- review	5
AHDSN: an attention-enabled hybrid deep sequential network for cancer survivability prediction from multi-omics data	5
Combined single-cell RNA sequencing and mendelian randomization to identify biomarkers associated with circadian rhythm in sarcopenia	5
Enhanced computational strategies for categorizing HER2 kinase domain variants of uncertain significance through structural and functional analysis	5
Mammalian genome research resources available from the National BioResource Project in Japan	4
Impact of IL-6 rs1800795 and rs1800796 polymorphisms on clinical outcomes of COVID-19: a study on severity of disease in Turkish population	4
Multi-omics analysis of HLTF context-dependent regulation across TCGA cohorts revealed its potential as new biomarker in tumour	4

Junctions in Jeopardy: the neuromuscular junction is a selective pathological target in Charcot-Marie-Tooth disease	4
Identification of prostate cancer associated genes for diagnosis and prognosis: a modernized in silico approach	4
Genetic factors underlying Mandibular prognathism: insights from recent human and animal studies	4
A comprehensive review of livestock development: insights into domestication, phylogenetics, diversity, and genomic advances	4
Genomic advancements in goat breeding: enhancing productivity, disease resistance, and sustainability in India’s rural economy	4
Inflammatory cytokines are associated with stroke and risk factors of cerebrovascular diseases: a Mendelian randomization study	4
Comprehensive analysis of breast cancer oxidative stress related gene signature: a combination of bulk and single-cell RNA sequencing analysis	4
Genome-wide detection of copy number variations in indigenous Red Sindhi cattle using ddRAD sequencing	4
Complementarity and integration of animal and in vitro non-animal pre-clinical model systems– an Australian perspective	4
Echo2Pheno: a deep-learning application to uncover echocardiographic phenotypes in conscious mice	4
Polyunsaturated fatty acid metabolism in the retinal pigment epithelium and its association with outer retinal disease	4
The interplay of hydrogen sulfide and microRNAs in cardiovascular diseases: insights and future perspectives	4
Identification of important gene signatures in schizophrenia through feature fusion and genetic algorithm	4
Genome-wide screening for genetic variants in polyadenylation signal (PAS) sites in mouse selection lines for fatness and leanness	4
Mouse phenome database: curated data repository with interactive multi-population and multi-trait analyses	4
CDC167 exhibits potential as a biomarker for airway inflammation in asthma	4
Identification and validation of PANX1 as an inflammasome-related biomarker in gestational diabetes mellitus: insights from machine learning and experimental approaches	4
Mapping copy number variable regions correlated with reproduction and production traits in Karan Fries cattle mammalian genomics	4
Genome assembly of the Neotropical marsh rat Holochilus nanus (Cricetidae: Sigmodontinae) brings insights on B and sex chromosome evolution	4
Recent advances in the genomic resources for sheep	4
Online Mendelian Inheritance in Animals (OMIA): a genetic resource for vertebrate animals	3
Retraction Note: Circ_0069718 promotes the progression of breast cancer by up-regulating NFIB through sequestering miR-590-5p	3
Intestinal cancer development in response to oral infection with high-fat diet-induced Type 2 diabetes (T2D) in collaborative cross mice under different host genetic background effects	3
Retraction Note: MiR-519d-3p enhances the sensitivity of non-small-cell lung cancer to tyrosine kinase inhibitors	3
Comprehensive ECG reference intervals in C57BL/6N substrains provide a generalizable guide for cardiac electrophysiology studies in mice	3
Integrated multi-omics and machine learning prioritize key immune genes for multiple sclerosis risk prediction	3
Genetic variation in the Y chromosome and sex-biased DNA methylation in somatic cells in the mouse	3
The future objectives of the International Mouse Phenotyping Consortium (IMPC): functional evaluation of human disease-relevant cis-regulatory elements in the mouse genome	3
The COL6A5-p.Glu2272* mutation induces chronic itch in mice	3
AFAP1-AS1 regulates oral squamous cell carcinoma development through the miR-93-3p/CCND1 signaling pathway	3
Genetic factors underlying host resistance to Rhipicephalus microplus tick infestation in Braford cattle: a systems biology perspective	3
The alliance of genome resources: transforming comparative genomics	3
Oncogenic role of LncRNA DLEU2 in thyroid cancer through a NAT10/USP39 regulatory axis	3
Telemedical monitoring in patients with inborn cardiac disease – experience of a tertiary care centre	3
Large-scale mouse mutagenesis identifies novel genes affecting vertebral anatomy	3
GWAS reveals genomic associations with swine inflammation and necrosis syndrome	3
Assessment of genome-wide genetic variability and population divergence of four native Turkish sheep breeds	3
Genome-wide insights into selection signatures for transcription factor binding sites in cattle ROH regions	3
Whole-genome sequencing and genomic analysis of Norduz goat (Capra hircus)	2
Promises and challenges of cardiac organoids	2
Mutation of the Thap4 gene causes dwarfism and testicular anomalies in rats and mice	2
Retraction Note: Overexpression of ROCK1 promotes cancer cell proliferation and is associated with poor prognosis in human urothelial bladder cancer	2
In search of epigenetic hallmarks of different tissues: an integrative omics study of horse liver, lung, and heart	2
Genome-wide selective sweep analysis in high-altitude Changthangi goats reveals candidate genes for pashmina fiber production	2
Canine models of inherited retinal diseases: from neglect to well-recognized translational value	2
Neuroinflammation in glaucoma: a myriad of cellular pathways and players	2
Retraction Note: CircRNA circ-ATAD1 is downregulated in endometrial cancer and suppresses cell invasion and migration by downregulating miR-10a through methylation	2
Persistent homology of blood gene co-expression networks reveals reduced cycle structure in autism spectrum disorder: a multi-cohort analysis	2
Identification of novel biomarkers for atherosclerosis using single-cell RNA sequencing and machine learning	2
Pyroptosis is involved in the immune microenvironment regulation of unexplained recurrent miscarriage	2
Causal relationship between imaging-derived phenotypes and neurodegenerative diseases: a Mendelian randomization study	2
The RSPO2 gene is associated with bilateral anterior amelia in Chihuahuas	2
Genomic insights into the recent evolution and biodiversity of Italian sheep breeds	2
Vascular contribution to cognitive impairment and dementia (VCID): proceedings of 2025 workshop of the Jackson Laboratory	2
Preclinical research (on rare diseases): we need to talk about health equity	2
A rationale for considering heart/brain axis control in neuropsychiatric disease	2
THBS1: a biomarker for PCOS and its role in pathogenesis via the PI3K/AKT signaling pathway	2
Transcriptome studies of inherited dilated cardiomyopathies	2
Generation and characterization of a knock-in mouse model for spastic tetraplegia, thin corpus callosum, and progressive microcephaly (SPATCCM)	2
The spontaneous mouse mutant low set ears (Lse) is caused by tandem duplication of Fgf3 and Fgf4	2
The effect of different approaches to determining the regularization parameter of bayesian LASSO on the accuracy of genomic prediction	2
Unraveling the genetic and physiological potential of donkeys: insights from genomics, proteomics, and metabolomics approaches	2
Assessing the causal relationship between immune cells and prostatitis: evidence from bidirectional mendelian randomization analysis	2
Fine-scale recombination rates inferred using the canFam4 assembly are strongly correlated with previous maps of dog recombination	2
Detection of selection signatures in indigenous African cattle reveals genomic footprints of adaptation, production and temperament traits	2
What to consider for ECG in mice—with special emphasis on telemetry	2
Rare and common variants in ERAP1 and ERAP2 selected for in response to Yersinia pestis infection contribute to autoimmune disease including inflammatory bowel disease	2
MiR-324-5p mitigates experimental acute pancreatitis by suppressing Rock2 expression	1
Comprehensive bioinformatics analysis and experimental validation reveal the role of circadian rhythm–related genes in the crosstalk between osteoporosis and atherosclerosis	1
Hypoxia-induced mechanism of TNBC promoting tumour cell proliferation through exosomal miRNA	1
m5c-modified LINC01094 participates in epithelial-mesenchymal transition and metastasis of cervical cancer cells via the ZNF582-SIRT1/p53 axis	1
Retraction Note to: miR-217-5p inhibits invasion and metastasis of prostate cancer by targeting clusterin	1
The use of genistein and ambroxol may be an effective approach in correcting cellular dysfunctions of mucopolysaccharidosis-plus syndrome	1
Beyond black and white: dissecting the genetic basis of skin depigmentation in Nellore cattle	1
Regulation of humeral fracture healing by miR-21 through SMAD7-mediated activation of Wnt/β-catenin signaling	1
Low-coverage whole-genome sequencing facilitates accurate and cost-effective haplotype reconstruction in complex mouse crosses	1
Genomic-microbial coevolution in human development: chromosome 2 fusion, and human accelerated regions	1
Mapping novel QTL and fine mapping of previously identified QTL associated with glucose tolerance using the collaborative cross mice	1
Genome-wide characterization of genetic diversity and breed discrimination markers in Tharparkar cattle	1
MicroRNA expression profiling of ovine epithelial cells stimulated with the Staphylococcus aureus in vitro	1

Exploring the mediating role of immune cells in the pathogenesis of IgA nephropathy through the inflammatory axis of gut microbiota from a genomic perspective	1
Fins, fur, and wings: the study of Tmem161b across species, and what it tells us about its function in the heart	1
Runs of homozygosity and signatures of selection for number of oocytes and embryos in the Gir Indicine cattle	1
Comprehensive identification of crucial biomarkers and therapeutic targets in cholestasis via integrated single-cell RNA and transcriptome sequencing analysis	1
Diverse wild-derived inbred strains provide a new community resource	1
Correction: Canine models of inherited retinal diseases: from neglect to well-recognized translational value	1
Exploring the mediating role of potential therapeutic genes in the pathogenesis of hypopituitarism through the metabolites from a genomic perspective	1
Retraction Note: LncRNA TLR8-AS1 suppresses miR-34a maturation in hepatocellular carcinoma to suppress cell proliferation and migration	1
Identification of cis-sQTL demonstrates genetic associations and functional implications of inflammatory processes in Nelore cattle muscle tissue	1
ZDHHC5 and ZDHHC14 promote depression via the mediation of double-negative T cells	1
Comprehensive selection signature analyses in dairy cattle exploiting purebred and crossbred genomic data	1
Identification of genetic biomarkers of blood cholesterol levels using whole gene pathogenicity modelling	1
Identification of biomarkers associated with phagocytosis regulatory factors in coronary artery disease using machine learning and network analysis	1
Mapping genomic adaptation to environmental heterogeneity in Indian native goat populations through landscape genomics	1
A graph theoretical approach to experimental prioritization in genome-scale investigations	1
Genome-wide association study identifies significant SNPs for milk production and stature traits in Karan Fries cattle	1
Retraction Note: CircRNA_0043691 sponges miR-873-3p to promote metastasis of gastric cancer	1
Mitral valve transcriptome analysis in thirty-four age-matched Cavalier King Charles Spaniels with or without congestive heart failure caused by myxomatous mitral valve disease	1
Protein family FAM241 in human and mouse	1
Exploring the therapeutic effect of melatonin targeting common biomarkers in testicular germ cell tumor, prostate adenocarcinoma, and male infertility: an integrated biology approach	1
Gut metabolites and functional recovery after ischemic stroke: a genetic perspective	1
Genetic diversity of North African populations in the 17q21 genomic region	1
Understanding PACS2 syndrome’s pathomechanism by studying E209K and E211K mutations	1
The evolution of AI-integrated genome editing and its challenges	1
The mouse metabolic phenotyping center (MMPC) live consortium: an NIH resource for in vivo characterization of mouse models of diabetes and obesity	1
Genomic architecture of insertion-deletion (indel) variants in beetal goats of India	1
A quality framework for cryopreserved rodent disease models: INFRAFRONTIER quality principles in EMMA archiving and distribution	1
Cataloging copy number variation regions and allied diversity in goat breeds spanning pan India	1
Cross-tissue enrichment patterns reveal functional clustering in normal human tissues from GTEx	1
Commentary: The International Mouse Phenotyping Consortium: high-throughput in vivo functional annotation of the mammalian genome	1
Integrative approaches to m6A and m5C RNA modifications in autism spectrum disorder revealing potential causal variants	1
Revealing the key role of cuproptosis in osteoporosis via the bioinformatic analysis and experimental validation of cuproptosis-related genes	1