OOIR: Observatory of International Research

Papers

(The TQCC of Amino Acids is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
Molecular binding mechanism and novel antidiabetic and anti-hypertensive bioactive peptides from fermented camel milk with anti-inflammatory activity in raw macrophages cell lines	92
Effects of maternal branched-chain amino acid and alanine supplementation on growth and biomarkers of protein metabolism in dams fed a low-protein diet and their offspring	84
Dietary L-arginine supplementation increases the hepatic expression of AMP-activated protein kinase in rats	78
Reply to homocysteine and copper ions: is their interaction responsible for cardiovascular‑related damage?	65
Proline oxidase silencing inhibits p53-dependent apoptosis in MCF-7 breast cancer cells	61
Cortisol enhances citrulline synthesis from proline in enterocytes of suckling piglets	60
Oral anserine supplementation does not attenuate type-2 diabetes or diabetic nephropathy in BTBR ob/ob mice	59
Antimicrobial peptidomes of Bothrops atrox and Bothrops jararacussu snake venoms	59
Carnosine and skeletal muscle dysfunction in a rodent multiple sclerosis model	59
Functional roles of polyamines and their metabolite acrolein in eukaryotic cells	44
Hydroxyproline in animal metabolism, nutrition, and cell signaling	44
BamA-targeted antimicrobial peptide design for enhanced efficacy and reduced toxicity	43
Branched-chain amino acids regulate intracellular protein turnover in porcine mammary epithelial cells	40
Development, validation of a GC–MS method for the simultaneous measurement of amino acids, their PTM metabolites and AGEs in human urine, and application to the bi-ethnic ASOS study with special empha	31
L-valine production in Corynebacterium glutamicum based on systematic metabolic engineering: progress and prospects	30
Screening of AS101 analog, organotellurolate (IV) compound 2 for its in vitro biocompatibility, anticancer, and antibacterial activities	27
Acetylcholine hydrolytic activity of fibrillated β-amyloid (1–40) peptide	26
Synthesis and dopamine receptor binding of dihydrexidine and SKF 38393 catecholamine-based analogues	25
PDZK1 improves ventricular remodeling in hypertensive rats by regulating the stability of the Mas receptor	25
Serum metabolomics study of narcolepsy type 1 based on ultra-performance liquid chromatography–tandem mass spectrometry	24
Protein cysteine S-glycosylation: oxidative hydrolysis of protein S-glycosidic bonds in aqueous alkaline environments	24
Paternal exposure to excessive methionine altered behavior and neurochemical activities in zebrafish offspring	23
Disruption of kynurenine pathway reveals physiological importance of tryptophan catabolism in Henosepilachna vigintioctopunctata	23
Deciphering the conformational landscape of few selected aromatic noncoded amino acids (NCAAs) for applications in rational design of peptide therapeutics	23
A strategy can be used to analyze intracellular interaction proteomics of cell-surface receptors	23

Synthesis and biological study of new galanthamine-peptide derivatives designed for prevention and treatment of Alzheimer’s disease	21
Editorial	21
Molecular species of oxidized phospholipids in brain differentiate between learning- and memory impaired and unimpaired aged rats	21
Divergent synthesis of biologically active l-threo-β-hydroxyaspartates from common trans-oxazolidine dicarboxylate	20
Global effects of RAB3GAP1 dysexpression on the proteome of mouse cortical neurons	19
PYCR, a key enzyme in proline metabolism, functions in tumorigenesis	19
Exploring details about structure requirements based on antioxidant tripeptide derived from β-Lactoglobulin by in silico approaches	19
Dietary supplementation with monosodium glutamate enhances milk production by lactating sows and the growth of suckling piglets	18
Oncogenic Ras expression increases cellular formate production	18
Untargeted metabolomics analysis of plasma metabolic characteristics in patients with acne and insulin resistance	18
Publisher’s Note: Phenolic compounds as histone deacetylase inhibitors: binding propensity and interaction insights from molecular docking and dynamics simulations	18
An assessment of the transport mechanism and intraneuronal stability of l-carnosine	18
Greater plasma essential amino acids and lower 3-methylhistidine with higher protein intake during endurance training: a randomised control trial	17
Insulin stimulates β-alanine uptake in skeletal muscle cells in vitro	17
Urinary excretion of asymmetric (ADMA) and symmetric (SDMA) dimethylarginine is positively related to nitric oxide level in tissues of normotensive and hypertensive rats	17
ACP-Dnnel: anti-coronavirus peptides’ prediction based on deep neural network ensemble learning	16
Antibiotics-induced dysbiosis in gut microbiota affects bumblebee health via regulating host amino acid metabolism	16
Apoptin NLS2 homodimerization strategy for improved antibacterial activity and bio-stability	16
Isozymes of P5C reductase (PYCR) in human diseases: focus on cancer	16
Transcriptome analysis of l-leucine-producing Corynebacterium glutamicum under the addition of trimethylglycine	16
Tryptophan regulates bile and nitrogen metabolism in two pig gut lactobacilli species in vitro based on metabolomics study	15
An efficient synthesis of cis-4-hydroxyphosphonic and cis-4-hydroxyphosphinic analogs of pipecolic acid from cyclic enaminones	15
Chiral secondary amino acids, their importance, and methods of analysis	14
Novel N-α-amino acid spacer-conjugated phthalimide–triazine derivatives: synthesis, antimicrobial and molecular docking studies	14
Targeting prostate cancer with docetaxel-loaded peptide 563-conjugated PEtOx-co-PEI30%-b-PCL polymeric micelle nanocarriers	14
Toward an understanding of tree frog (Hyla japonica) for predator deterrence	14
Metagenomics-based inference of microbial metabolism towards neuroactive amino acids and the response to antibiotics in piglet colon	14
The use of BCAA to decrease delayed-onset muscle soreness after a single bout of exercise: a systematic review and meta-analysis	14
Association between the antioxidant properties of SESN proteins and anti-cancer therapies	13
Effects of taurine on vascular tone	13
Amnio acid substitution at position 298 of human glucose-6 phosphatase-α significantly impacts its stability in mammalian cells	13
Impact of probiotic Limosilactobacillus reuteri DSM 17938 on amino acid metabolism in the healthy newborn mouse	13
Trace assay of insulin in a pharmacy drug with a paste electrode	12
Research progress on the role of cationic amino acid transporter (CAT) family members in malignant tumors and immune microenvironment	12
K-aurein: A notable aurein 1.2-derived peptide that modulates Candida albicans filamentation and reduces biofilm biomass	12
Excessive dietary L-tryptophan regulated amino acids metabolism and serotonin signaling in the colon of weaning piglets with acetate-induced gut inflammation	12
Insights into the synthesis strategies of plant-derived cyclotides	12
Escherichia coli infection activates the production of IFN-α and IFN-β via the JAK1/STAT1/2 signaling pathway in lung cells	12
Purification, conformational analysis and cytotoxic activities of host-defense peptides from the Tungara frog Engystomops pustulosus (Leptodactylidae; Leiuperinae)	12
Cystine reduces mitochondrial dysfunction in C2C12 myotubes under moderate oxidative stress induced by H2O2	12
Dual effects of the tryptophan-derived bacterial metabolite indole on colonic epithelial cell metabolism and physiology: comparison with its co-metabolite indoxyl sulfate	11
PepTraq: a toolbox for in silico data mining and fast sequence filtering	11
Impact of chemical modifications on the antimicrobial and hemolytic activity of helical amphipathic peptide Lasioglossin LL-III	11
β-Aminoisobutyric acid supplementation attenuated salt-sensitive hypertension in Dahl salt-sensitive rats through prevention of insufficient fumarase	11
Effect of substituting glutamine with lysine on structural and biological properties of antimicrobial peptide Polybia-MP1	11
Acetyl group for proper protection of β-sugar-amino acids used in SPPS	11
Biochemical and in silico molecular study of caffeic acid-O-methyltransferase enzyme associated with lignin deposition in tall fescue	11
Measurement of S-glutathionylated proteins by HPLC	11
PTPAMP: prediction tool for plant-derived antimicrobial peptides	11
Bromelain and ficin proteolytic effects on gliadin cytotoxicity and expression of genes involved in cell-tight junctions in Caco-2 cells	11

Identification of a peptide that crosses the blood-cerebrospinal fluid barrier by phage display technology	11
Serum and urinary carnosinase-1 correlate with kidney function and inflammation	10
Polyglutamylation: biology and analysis	10
Proline metabolism and redox; maintaining a balance in health and disease	10
In silico and in vivo neuropharmacological evaluation of two γ-amino acid isomers derived from 2,3-disubstituted benzofurans, as ligands of GluN1–GluN2A NMDA receptor	10
Estimation of bioactive peptide content of milk from different species using an in silico method	10
Characterization of thermostable serine hydroxymethyltransferase for β-hydroxy amino acids synthesis	10
Amino acids, post-translational modifications, nitric oxide, and oxidative stress in serum and urine of long COVID and ex COVID human subjects	10
Sulbactam improves binding property and uptake capacity of glutamate transporter-1 and decreases glutamate concentration in the CA1 region of hippocampus of global brain ischemic rats	10
Peptide OA-VI12 restrains melanogenesis in B16 cells and C57B/6 mouse ear skin via the miR-122-5p/Mitf/Tyr axis	10
Antineoplastic activity of plant-derived compounds mediated through inhibition of histone deacetylase: a review	10
The effects of collagen peptide supplementation on body composition, collagen synthesis, and recovery from joint injury and exercise: a systematic review	9
Chromogranin A-derived peptides pancreastatin and catestatin: emerging therapeutic target for diabetes	9
Correction to: The novel inhibitors of serine proteases	9
Common pathogenic bacteria-induced reprogramming of the host proteinogenic amino acids metabolism	9
Characterization of a polyclonal antibody that is highly selective for the d-isoAsp-25 variant of mammalian histone H2B	9
Proline metabolism in cancer	9
Biocidal and antibiofilm activities of arginine-based surfactants against Candida isolates	9
Ferrihydrite synthesis in the presence of amino acids and artificial seawater	9
Neuroprotective effect of newly synthesized 4-aminopyridine derivatives on cuprizone-induced demyelination in mice—a behavioral and immunohistochemical study	9
Possible role of SIRT1 and SIRT3 in post-translational modifications in human breast milk during the neonatal period	9
PepQSAR: a comprehensive data source and information platform for peptide quantitative structure–activity relationships	9
The association of fasting plasma thiol fractions with body fat compartments, biomarker profile, and adipose tissue gene expression	9
The serum amino acid profile in COVID-19	9
Alkali salts of amino acids as alkaline additives for neutralization of acidic corrosion inhibitors	9
Amino acid analysis as a method of discovering biomarkers for diagnosis of diabetes and its complications	9