OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Gastroenterology is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
The external validation of Dallas Steatosis Index among Asian population: a useful tool for metabolic dysfunction-associated steatotic liver disease identification and prevention	316
Temporal trends in obesity and its prognostic impact in Korean patients with inflammatory bowel disease	247
WWP1 inhibition suppresses the proliferation of pancreatic cancer cells by regulating the PI3K-AKT pathway	176
Revisiting the relationship between thyroid function and metabolic dysfunction-associated steatotic liver disease in the era of resmetirom	138
A revolutionary oral HBV treatment candidate as innovative therapeutic approach warranting clinical trials	95
Efficacy, tolerability, and safety of oral sulfate tablet versus 2 L-polyethylene glycol/ascorbate for bowel preparation in older patients: prospective, multicenter, investigator single-blinded, rando	85
Mucosal and faecal neutrophil gelatinase-associated lipocalin as potential biomarkers for collagenous colitis	73
LAT1 expression influences Paneth cell number and tumor development in ApcMin/+ mice	64
Leucine-rich alpha-2 glycoprotein is a potential biomarker to monitor disease activity in inflammatory bowel disease receiving adalimumab: PLANET study	56
A clinicopathological study of IgG4-related autoimmune hepatitis and IgG4-hepatopathy	53
Diagnostic accuracy and cut-off values of serum leucine-rich alpha-2 glycoprotein for Crohn’s disease activity in the small bowel	46
Serum zinc levels as predictors of covert hepatic encephalopathy in patients with liver cirrhosis	45
Alpha-fetoprotein combined with initial tumor shape irregularity in predicting the survival of patients with advanced hepatocellular carcinoma treated with immune-checkpoint inhibitors: a retrospectiv	43
Impact of preceding treatment for head and neck squamous cell carcinoma on synchronous superficial esophageal squamous cell carcinoma	42
Alcohol-associated liver disease increases the risk of muscle loss and mortality in patients with cirrhosis	38
Utility of a new automated diagnostic program in high-resolution esophageal manometry	37
HBeAg-positive patients with HBsAg < 100 IU/mL and negative HBV RNA have lower risk of virological relapse after nucleos(t)ide analogues cessation	37
The clinical efficacy of azathioprine as maintenance treatment for autoimmune pancreatitis: a systematic review and meta-analysis	37
Ratio of submucosal thickness to total bowel wall thickness as a new sonographic parameter to estimate endoscopic remission of ulcerative colitis	36
Serum soluble programmed death-1 levels predict the spontaneous HBeAg seroclearance in chronic hepatitis B	35
Metformin use is not associated with reduced risk of older onset inflammatory bowel disease: a Danish nationwide population-based study	32
Upregulation of BMI1-suppressor miRNAs (miR-200c, miR-203) during terminal differentiation of colon epithelial cells	30
A review on the current status and definitions of activity indices in inflammatory bowel disease: how to use indices for precise evaluation	30
The useful predictors of zinc deficiency for the management of chronic liver disease	29
Risk of gastric and oesophageal adenocarcinoma following discontinuation of long-term proton-pump inhibitor therapy	26

Renal manifestations in inflammatory bowel disease: a systematic review	26
Correction to: Composite detection rate as an upper gastrointestinal endoscopy quality measure correlating with detection of neoplasia	26
Transcriptomic profiling on localized gastric cancer identified CPLX1 as a gene promoting malignant phenotype of gastric cancer and a predictor of recurrence after surgery and subsequent chemotherapy	25
Risk of gastric and oesophageal adenocarcinoma following discontinuation of long-term proton-pump inhibitor therapy	24
The role of sex hormones in the fecal microbiota of IBS-D patients with exacerbation of symptoms deserves attention	24
The first comprehensive genomic characterization of rectal squamous cell carcinoma	24
Integrated analysis of tertiary lymphoid structures in relation to tumor-infiltrating lymphocytes and patient survival in pancreatic ductal adenocarcinoma	24
The role of stromal BMP/CXCL12 signaling axis in serrated polyp development	23
Risk of gastric and oesophageal adenocarcinomas following discontinuation of long-term proton-pump inhibitor therapy	23
High-risk population of progressive hepatic fibrosis in chronic hepatitis B patients on antiviral therapy	23
Correlation between mismatch repair and survival of patients with gastric cancer after 5-FU-based adjuvant chemotherapy	22
Further notice of omics profiles of fecal and oral microbiota change in irritable bowel syndrome patients with diarrhea and symptom exacerbation	22
Clinicopathologic differences of gastric neoplasms between Helicobacter pylori-infected and -naïve patients: a multicenter retrospective analysis	21
Computer-aided demarcation of early gastric cancer: a pilot comparative study with endoscopists	21
Induction of ferroptosis by photodynamic therapy and enhancement of antitumor effect with ferroptosis inducers	21
Clinical outcome after cessation of nucleos(t)ide analog treatment in chronic hepatitis B patients who achieved HBsAg seroclearance	20
Red dichromatic imaging and linked color imaging as reliable image-enhanced endoscopic procedures for detecting the distal end of the palisade vessels in the columnar metaplastic mucosa of the gastroe	18
Novel scale for evaluating the therapeutic efficacy of per-oral endoscopic myotomy in achalasia	18
The interplay between alterations in esophageal microbiota associated with Th17 immune response and impaired LC20 phosphorylation in achalasia	18
Assessing the side effects and resistance in H. pylori treatment: a discussion on minocycline versus tetracycline therapy	18
Three-dimensional chromatin landscapes in hepatocellular carcinoma associated with hepatitis B virus	18
Correction: Association of ulcerative colitis symptom severity and proctocolectomy with multidimensional patient-reported outcomes: a cross-sectional study	17
Prevalence of colonoscopy in Japan using a large-scale health claims data compared to esophagogastroduodenoscopy	17
Corynoline protects chronic pancreatitis via binding to PSMA2 and alleviating pancreatic fibrosis	16
Dietary vitamin D intake and risk of colorectal cancer according to vitamin D receptor expression in tumors and their surrounding stroma	16
A combination of bowel wall thickness and submucosa index is useful for estimating endoscopic improvement in ulcerative colitis: external validation of the Kyorin Ultrasound Criterion	16
Response to the letter by Buldukoglu et al. regarding our manuscript “Body mass index and survival among patients with advanced biliary tract cancer: a single-institutional study with nationwide data-	16
Single-molecule sequencing of the whole HCV genome revealed envelope deletions in decompensated cirrhosis associated with NS2 and NS5A mutations	16
Correction: Urinary dipeptidase 1 and trefoil factor 1 are promising biomarkers for early diagnosis of colorectal cancer	16
Managing radiation safety and protection in gastroenterology in Japan: insights from the REX-GI study	16
Development of a novel oncolytic adenovirus controlled by CDX2 promoter for esophageal adenocarcinoma therapy	16
Current management and future perspectives of covert hepatic encephalopathy in Japan: a nationwide survey	15
Treatment strategy after noncurative endoscopic resection for early gastric cancers in patients aged ≥ 85 years: a multicenter retrospective study in a highly aged area of Japan	15
The magnetic resonance imaging and age-adjusted matrix metalloproteinase-7 assist the diagnosis of biliary atresia	15
Multistage deep learning for classification of Helicobacter pylori infection status using endoscopic images	15
Omics profiles of fecal and oral microbiota change in irritable bowel syndrome patients with diarrhea and symptom exacerbation	15
Low HDL cholesterol levels in women and hypertriglyceridemia in men: predictors of MASLD onset in individuals without steatosis	15
Characterization of tumor microbiome and associations with prognosis in intrahepatic cholangiocarcinoma	14
Non-alcoholic fatty liver disease in patients with morbid obesity: the gut microbiota axis as a potential pathophysiology mechanism	14
Deep learning-based automated quantification of goblet cell mucus using histological images as a predictor of clinical relapse of ulcerative colitis with endoscopic remission	14
Efficacy of endoscopic ultrasound-guided tissue acquisition for solid pancreatic lesions 20 mm or less in diameter suspected as neuroendocrine tumors or requiring differentiation	14
Pathogenic effects of Desulfovibrio in the gut on fatty liver in diet-induced obese mice and children with obesity	14
Adjuvant immune checkpoint inhibitors associated with higher recurrence-free survival in postoperative hepatocellular carcinoma (PREVENT): a prospective, multicentric cohort study	14
Resistance exercise in combination with aerobic exercise reduces the incidence of serious events in patients with liver cirrhosis: a meta-analysis of randomized controlled trials	14
Non-invasive early detection on esophageal squamous cell carcinoma and precancerous lesions by microbial biomarkers combining epidemiological factors in China	14
Clinical features and oncological outcomes of intestinal cancers associated with ulcerative colitis and Crohn’s disease	13
Acute kidney injury development is associated with mortality in Japanese patients with cirrhosis: impact of amino acid imbalance	13
CACNA2D1 regulates the progression and influences the microenvironment of colon cancer	13
Blockade of C5aR1 alleviates liver inflammation and fibrosis in a mouse model of NASH by regulating TLR4 signaling and macrophage polarization	13
Controversy regarding the risk of autoimmune gastritis on gastric adenocarcinoma	13

Gut microbiota and metabolites of cirrhotic portal hypertension: a novel target on the therapeutic regulation	12
Genomic profile and clinical features of MSI-H and TMB-high pancreatic cancers: real-world data from C-CAT database	11
MAFLD: an optimal framework for understanding liver cancer phenotypes	11
Prevalence and predictability of the Chicago Classification of Pouchitis in ulcerative colitis: a multicenter study in Japan	11
Artificial intelligence (AI) models for the ultrasonographic diagnosis of liver tumors and comparison of diagnostic accuracies between AI and human experts	11
Acknowledgements	11
Characteristics of colorectal neuroendocrine tumors in patients prospectively enrolled in a Japanese multicenter study: a first report from the C-NET STUDY	11
Proposal of discontinuation criteria of atezolizumab plus bevacizumab after curative conversion therapy for unresectable early-to-intermediate-stage hepatocellular carcinoma: a multicenter proof-of-co	11
Serum IL-6 concentration is a useful biomarker to predict the efficacy of atezolizumab plus bevacizumab in patients with hepatocellular carcinoma	11
New chemiluminescent enzyme immunoassay for quantitative measurement of Mac-2 binding protein glycosylation isomer in chronic liver disease	10
Anti-integrin αvβ6 autoantibodies in patients with primary sclerosing cholangitis	10
Pancreatic atrophy and recovery after allogeneic hematopoietic cell transplantation	10
Current status of molecular diagnostic approaches using liquid biopsy	10
Reply to ‘C-CAT's triumph in gastroenterology: the wisdom of cats is infinitely superior’	10
Acknowledgements	10
Considerations for evaluating antibiotic prophylaxis in cirrhotic patients with upper gastrointestinal bleeding in real-world data	10
Elevated A2F bisect N-glycans of serum IgA reflect progression of liver fibrosis in patients with MASLD	10
Definitive-dose adjuvant radiotherapy following endoscopic submucosal dissection for superficial esophageal cancer	10
Standard technique in Japan for measuring hepatic venous pressure gradient	10
Treatment with vonoprazan for 3 weeks is not inferior to 8 weeks for the management of gastric ESD: a multicenter noninferiority randomized study	10
Trajectory analyses to identify persistently low responders to COVID-19 vaccination in patients with inflammatory bowel disease: a prospective multicentre controlled study, J-COMBAT	10
Clinical development of a blood biomarker using apolipoprotein-A2 isoforms for early detection of pancreatic cancer	10
Clinicopathological features and prognosis of primary small bowel adenocarcinoma: a large multicenter analysis of the JSCCR database in Japan	10
Usefulness of serum HBV RNA levels for predicting antiviral response to entecavir treatment in patients with chronic hepatitis B	10
Association between homologous recombination deficiency and time to treatment failure to platinum-based chemotherapy for pancreatic cancer by using the C-CAT database	10
The clonal heterogeneity of colon cancer with liver metastases	10
Hepatitis C virus eradication prolongs overall survival in hepatocellular carcinoma patients receiving molecular-targeted agents	10
Mouse IgA modulates human gut microbiota with inflammatory bowel disease patients	9
Promising modality for severe ulcerative colitis: infliximab and plant-based diet as first-line (IPF) therapy	9
A survey questionnaire evaluating physical activity patterns and determinants in patients with chronic liver disease	9
Reply to: Minocycline versus tetracycline in bismuth-containing quadruple therapy for Helicobacter pylori rescue treatment: a multicentre, randomized controlled trial	9
Arginase 2 attenuates ulcerative colitis by antioxidant effects of spermidine	9
Role of combined aerobic and resistance exercise in liver cirrhosis	9
MicroRNA-223-3p levels in serum-derived extracellular vesicles predict regression of M2BPGi-based liver fibrosis after hepatitis C virus eradication by direct-acting antiviral agents	9
Nrf2/ASPM axis regulated vasculogenic mimicry formation in hepatocellular carcinoma under hypoxia	8
Small extracellular vesicles derived from adipose mesenchymal stem cells alleviate intestinal fibrosis by inhibiting the FAK/Akt signaling pathway via MFGE8	8
Clinical factors to predict changes of esophagogastric varices after sustained viral response with direct-acting antiviral therapy	8
Advances in omics data for eosinophilic esophagitis: moving towards multi-omics analyses	8
The risk stratification and predictive performance of a new combined polygenic risk score for hepatocellular carcinoma	8
Association of pancreatic atrophy patterns with intraductal extension of early pancreatic ductal adenocarcinoma: a multicenter retrospective study	8
Determination of optimal cutoff value of ulcerative colitis intestinal ultrasound index to estimate endoscopic improvement in ulcerative colitis	8
Prognostic factors of second-line nivolumab monotherapy for unresectable or metastatic esophageal cancer: a multi-institutional cohort study for 184 cases	8
Association of circulating cytokine levels and tissue-infiltrating myeloid cells with achalasia: results from Mendelian randomization and validation through clinical characteristics and single-cell RN	8
Multisample lipidomic profiles of irritable bowel syndrome and irritable bowel syndrome-like symptoms in patients with inflammatory bowel disease: new insight into the recognition of the same symptoms	8