Matrix Biology

Article	Citations
Combined genetic-pharmacologic inactivation of tightly linked ADAMTS proteases in temporally specific windows uncovers distinct roles for versican proteolysis and glypican-6 in cardiac development	62
Optic neuropathy associated with TGFβ dysregulation in mice with a glaucoma-causative mutation of ADAMTS10	60
Basement membrane structure and function: Relating biology to mechanics	48
ADAMTS6 cleaves the large latent TGFβ complex and increases the mechanotension of cells to activate TGFβ	46
Role of extracellular space and matrix remodeling in cardiac amyloidosis	45
Transmembrane and multiplexin collagens in development and pathobiology	44
Thrombospondin-1 promotes mechanical stress-mediated ligamentum flavum hypertrophy through the TGFβ1/Smad3 signaling pathway	42
Beyond the matrisome: New frontiers in ECM research	40
Editorial Board	39
Collagen XVIII regulates extracellular matrix integrity in the developing nephrons and impacts nephron progenitor cell behavior	39
Tumor and stroma COL8A1 secretion induces autocrine and paracrine progression signaling in pancreatic ductal adenocarcinoma	38
The dynamic kidney matrisome - is the circadian clock in control?	37
Targeting the αVβ3/NgR2 pathway in neuroendocrine prostate cancer	35
A top-down approach to uncover the hidden ligandome of low-density lipoprotein receptor-related protein 1 in cartilage	35
Hyperglycemic environments directly compromise intestinal epithelial barrier function in an organoid model and hyaluronan (∼35 kDa) protects via a layilin dependent mechanism	33
Obesity impairs skeletal muscle repair through NID-1 mediated extracellular matrix remodeling by mesenchymal progenitors	33
Identification of Periostin as a critical niche for myofibroblast dynamics and fibrosis during tendon healing	32
Basement membrane components define the microenvironment of aggregated fibroblasts in the skin and support their aggregation in vitro	31
Neurocan regulates axon initial segment organization and neuronal activity	30
Effects of hydrostatic pressure, osmotic pressure, and confinement on extracellular matrix associated responses in the nucleus pulposus cells ex vivo	29
Tumor-associated fibrosis impairs the response to immunotherapy	29
Temporally and spatially regulated collagen XVIII isoforms are involved in ureteric tree development via the TSP1-like domain	29
The epidermal integrin-mediated secretome regulates the skin microenvironment during tumorigenesis and repair	28
Age related changes in hyaluronan expression leads to Meibomian gland dysfunction	28
Nanoscale characterization of collagen structural responses to in situ loading in rat Achilles tendons	28

Molecular and epigenetic ex vivo profiling of testis cancer-associated fibroblasts and their interaction with germ cell tumor cells and macrophages	27
Airway macrophage specific glycocalyx expression and remodeling following viral infection	27
Retraction Notice to “RETRACTED: The angiostatic molecule Multimerin 2 is processed by MMP-9 to allow sprouting angiogenesis”	27
Corrigendum to “Laminin-511-functionalized fibrin gel enables in-gel proliferation of human induced pluripotent stem cells” [Matrix Biology Volume 142, December 2025, Pages 21–32]	27
Editorial Board	27
Fibroblast integrin α11β1 is a collagen assembly receptor in mechanoregulated fibrillar adhesions	27
High hyaluronan binding and RHAMM expression identify an invasive and metastatic subpopulation in androgen-resistant prostate cancer cells	26
Dysfunctional latent transforming growth factor β activation after corneal injury in a classical Ehlers–Danlos model	26
Inhibition of the MRTF-A/SRF signaling axis alleviates vocal fold scarring	26
Sdc4 deletion perturbs intervertebral disc matrix homeostasis and promotes early osteopenia in the aging mouse spine	25
The integral role of fibronectin in skeletal morphogenesis and pathogenesis	25
Peptide location fingerprinting identifies structural alterations within basement membrane components in ageing kidney	25
Collagen VII maintains proteostasis in dermal fibroblasts by scaffolding TANGO1 cargo	25
Secreted ADAMTS-like 2 promotes myoblast differentiation by potentiating WNT signaling	24
Mitochondrial DNA mutations attenuate Bleomycin-induced dermal fibrosis by inhibiting differentiation into myofibroblasts	24
Hyaluronan in the pathogenesis of acute and post-acute COVID-19 infection	24
Different molecular weights of hyaluronan research in knee osteoarthritis: A state-of-the-art review	24
Matricellular protein CCN1 promotes collagen alignment and scar integrity after myocardial infarction	23
Global, but not chondrocyte-specific, MT1-MMP deficiency in adult mice causes inflammatory arthritis	23
Tissue mechanics coevolves with fibrillar matrisomes in healthy and fibrotic tissues	23
Furin-like cleavage at the C1-C2 linker region of the ⍺3 chain is not required for collagen VI assembly	23
Loss of col4a1 in zebrafish recapitulates the cerebrovascular phenotypes associated with monogenic cerebral small vessel disease	23
Lumican-mediated fibroblast differentiation in skin fibrosis	22
Liver-derived, circulating plasma fibronectin regulates trabecular bone mass and bone formation in adult male mice and its levels in sera associates with bone density in aging men	22
Spatial localization of collagen hydroxylated proline site variation as an ancestral trait in the breast cancer microenvironment	22
George R. Martin: Pioneering matrix biologist	22
Tonic repression of collagen I by the bradykinin receptor 2 in skin fibroblasts	21
RIPK3-MLKL signaling activates mitochondrial CaMKII and drives intrarenal extracellular matrix production during CKD	21
35kDa hyaluronan ameliorates ethanol driven loss of anti-microbial defense and intestinal barrier integrity in a TLR4-dependent manner	21
An integrin α3β1-CSTF3 signaling axis regulates alternative polyadenylation of Mmp9 mRNA	21
Mysteries of the collagen triple helix	21
Editorial Board	20
Loss of type III collagen has limited effect on tendon healing in young adult mice	20
Lamellar thickness measurements in control and osteogenesis imperfecta human bone, with development of a method of automated thickness averaging to simplify quantitation	20
Editorial Board	20
The structural organisation of pentraxin-3 and its interactions with heavy chains of inter-α-inhibitor regulate crosslinking of the hyaluronan matrix	20
Toward a rational therapeutic for elastin related disease: Key considerations for elastin based regenerative medicine strategies	19
The INSR/AKT/mTOR pathway regulates the pace of myogenesis in a syndecan-3-dependent manner	19
Chemotherapy treatment induces pro-invasive changes in liver ECM composition	19
LPA-induced expression of CCN2 in muscular fibro/adipogenic progenitors (FAPs): Unraveling cellular communication networks	19
Hypoxia and ascorbic acid: two interconnected microenvironmental factors driving collagen biosynthesis	18
Amelogenin proteolysis orchestrates functional amyloid pathways in enamel development	18
Remodeling of the extracellular matrix by serine proteases as a prerequisite for cancer initiation and progression	18
Editorial Board	18
Collagen IV biosynthesis: Intracellular choreography of post-translational modifications	18
FAM20C and FAM20A in normal and ectopic mineralization: A focus on oro-renal syndromes	17
Role of syndecan-4 in angiogenesis and vasculogenic mimicry in triple negative breast cancer cells	17
Glutamine-dependent changes in fibroblast-derived extracellular matrix dictate cancer cell behavior	17
Extracellular matrix integrity regulates GABAergic plasticity in the hippocampus	17
Mechanical control of breast cancer malignancy by promotion of mevalonate pathway enzyme synthesis	17

What does it take to be a collagen receptor?	17
Heparan sulfate buffers the bone resorptive activity of Cathepsin K in bone homeostasis	17
Mechanistic interrogation of mutation-independent disease modulators of RDEB identifies the small leucine-rich proteoglycan PRELP as a TGF-β antagonist and inhibitor of fibrosis	17
Biomechanical and compositional basement membrane defects due to a Col4a1 mutation affect cardiac morphology and function	17
Collagen VI deposition mediates stromal T cell trapping through inhibition of T cell motility in the prostate tumor microenvironment	17
An interview with Valerie Horsley	16
Fiber alignment in 3D collagen networks as a biophysical marker for cell contractility	16
Structural insights on perlecan and Schwartz–Jampel syndrome	16
S100A4 a classical DAMP as a therapeutic target in fibrosis	15
Circulating collagen type I fragments as specific biomarkers of cardiovascular outcome risk: Where are the opportunities?	15
Human intestinal myofibroblasts deposited collagen VI enhances adhesiveness for T cells – A novel mechanism for maintenance of intestinal inflammation	15
C-terminally clustered UGDH hypomorphic variants reveal subtle mechanisms of cellular and developmental disruption	15
IGF-II regulates lysyl oxidase propeptide and mediates its effects in part via basic helix-loop-helix E40	14
Involvement of lysophosphatidic acid-LPA1-YAP signaling in healthy and pathological FAPs migration	14
Editorial Board	14
Controlled extracellular proteolysis of thrombospondins	14
Mmp14 is required for matrisome homeostasis and circadian rhythm in fibroblasts	14
En route towards a personalized medicine approach: Innovative therapeutic modalities for connective tissue disorders	14
SIRT4 protects against intestinal fibrosis by facilitating GLS1 degradation	14
Conditional expression of endorepellin in the tumor vasculature attenuates breast cancer growth, angiogenesis and hyaluronan deposition	14
Fibrolamellar carcinomas–growth arrested by paracrine signals complexed with synthesized 3-O sulfated heparan sulfate oligosaccharides	14
Dynamic regulation of the tissue microenvironment by integrins and the extracellular matrix	13
Mechanical loading is required for initiation of extracellular matrix deposition at the developing murine myotendinous junction	13
Matrix bound nanovesicles: A great promise for TERM in less than a decade of research	13
Health consequences of mutant cartilage oligomeric matrix protein and its relationship to abnormal growth and joint degeneration	13
Matrix stiffness increases energy efficiency of endothelial cells	13
Site-specific glycosylation of proteoglycans: A revisited frontier in proteoglycan research	13
CD45+/ Col I+ Fibrocytes: Major source of collagen in the fibrotic lung, but not in passaged fibroblast cultures	13
Cancer-associated fibroblasts promote proliferation, angiogenesis, metastasis and immunosuppression in gastric cancer	13
Collagen VI ablation in zebrafish causes neuromuscular defects during developmental and adult stages	13
Tenascin‑C promotes epidural fibrosis via regulating caveolin-1-mediated TGFβRI internalization	13
Loss of BTK ameliorates the pathological cardiac fibrosis and dysfunction	13
Editorial Board	13
The phosphorylation of serine55 in enamelin is essential for murine amelogenesis	12
The life cycle of type IV collagen	12
Arylsulfatase I is a novel lysosomal chondroitin endosulfatase regulating endochondral ossification	12
Impact of vascular Ehlers-Danlos Syndrome-associated Gly substitutions on structure, function, and mechanics using bacterial collagen	12
Corrigendum to “Fibrolamellar carcinomas–growth arrested by paracrine signals complexed with synthesized 3-O sulfated heparan sulfate oligosaccharides” [Matrix Biology 121(August 2023), 194–216]	12
Cleavage of Cartilage Oligomeric Matrix Protein (COMP) by ADAMTS4 generates a neoepitope associated with osteoarthritis and other forms of degenerative joint disease	12
Cell differentiation and matrix organization are differentially affected during bone formation in osteogenesis imperfecta zebrafish models with different genetic defects impacting collagen type I stru	12
Myeloid deficiency of heparan sulfate 6-O-endosulfatases impairs bone marrow hematopoiesis	12
Novel insights into the role of Discoidin domain receptor 2 (DDR2) in cancer progression: a new avenue of therapeutic intervention	12
Integrins and integrin-driven secretory pathways as multi-dimensional regulators of tumor-associated macrophage recruitment and reprogramming in tumor microenvironment	12
The cost of convenient truths: artificial intelligence in matrix biology	12
Editorial Board	12
Tissue-specific collagen hydroxylation at GEP/GDP triplets mediated by P4HA2	12
AβPP-tau-HAS1 axis trigger HAS1-related nuclear speckles and gene transcription in Alzheimer's disease	12
A role for decorin in improving motor deficits after traumatic brain injury	12
Vertebrate extracellular matrix protein hemicentin-1 interacts physically and genetically with basement membrane protein nidogen-2	12
Drosophila Col4a1 Glycine mutations highlight allelic heterogeneity and mechanistic pleiotropy	11
Interleukin-1α inhibits transforming growth factor-β1 and β2-induced extracellular matrix production, remodeling and signaling in human lung fibroblasts: Master regulator in lung mucosal repair	11
Editorial Board	11
Editorial Board	11
Suppression of OGN in lung myofibroblasts attenuates pulmonary fibrosis by inhibiting integrin αv-mediated TGF-β/Smad pathway activation	11
Using load to improve tendon/ligament tissue engineering and develop novel treatments for tendinopathy	11
Dual role of enhancer of zeste homolog 2 in the regulation of ultraviolet radiation-induced matrix metalloproteinase-1 and type I procollagen expression in human dermal fibroblasts	10
Collagen prolyl 4-hydroxylase isoenzymes I and II have sequence specificity towards different X-Pro-Gly triplets	10
Mutant MESD links cellular stress to type I collagen aggregation in osteogenesis imperfecta type XX	10
A lysyl oxidase-responsive collagen peptide illuminates collagen remodeling in wound healing	10
Dual transgene amelioration of Lama2-null muscular dystrophy	10
Emilin2 fosters vascular stability by promoting pericyte recruitment	10
Zebrafish col4a1 loss-of-function models mirror key neurovascular and ocular features of COL4A1/A2 syndrome and enable human variants assessment in vivo	10
Laminin-511-functionalized fibrin gel enables in-gel proliferation of human induced pluripotent stem cells	10
Editorial Board	10
Fibronectin isoforms promote postnatal skeletal development	10
Editorial Board	10
Heparanase 2 (Hpa2) attenuates the growth of human sarcoma	9
Calponin 1 increases cancer-associated fibroblasts-mediated matrix stiffness to promote chemoresistance in gastric cancer	9
Editorial Board	9
Collagen diversity in human skin: Aging, wound healing, and disorders	9
Metabolic control of collagen synthesis	9
Decoding the MMP14 integrin link: Key player in the secretome landscape	9
Alterations in the microenvironment of junctional epidermolysis bullosa keratinocytes: A gene expression study	8
Editorial Board	8
Fibrillin-1 G234D mutation in the hybrid1 domain causes tight skin associated with dysregulated elastogenesis and increased collagen cross-linking in mice	8
Cytokine conversations: Fibroblasts shape macrophage identity to enhance collagen clearance	8
The gelatinases, matrix metalloproteinases 2 and 9, play individual roles in skeleton development	8
Versican provides the provisional matrix for uterine spiral artery dilation and fetal growth	8
Laminin γ1 chain is essential for the cardiorespiratory and muscular systems	8
Corrigendum to “Biglycan, a novel trigger of Th1 and Th17 cell recruitment into the kidney” [Matrix Biology 68–69 (2018) 293–317]	8

The endocytic receptor uPARAP is a regulator of extracellular thrombospondin-1	8
Increased expression of the pathological O-glycosylated form of oncofetal fibronectin in the multidrug resistance phenotype of cancer cells	8
Activation of skeletal muscle FAPs by LPA requires the Hippo signaling via the FAK pathway	8