Matrix Biology

Article	Citations
The INSR/AKT/mTOR pathway regulates the pace of myogenesis in a syndecan-3-dependent manner	52
Editorial Board	52
Editorial Board	47
Circulating hyaluronic acid signature in CAP and ARDS – the role of pneumolysin in hyaluronic acid shedding	42
Peptide location fingerprinting identifies species- and tissue-conserved structural remodelling of proteins as a consequence of ageing and disease	40
Site-specific glycosylation of proteoglycans: A revisited frontier in proteoglycan research	36
The fibroblast hormone Endotrophin is a biomarker of mortality in chronic diseases	33
Autophagy, tissue repair, and fibrosis: a delicate balance	32
A CNA-35-based high-throughput fibrosis assay reveals ORAI1 as a regulator of collagen release from pancreatic stellate cells	29
Basement membranes in lung metastasis growth and progression	28
TGF-β induces matrisome pathological alterations and EMT in patient-derived prostate cancer tumoroids	27
Surveillance of nucleolar homeostasis and ribosome maturation by autophagy and the ubiquitin-proteasome system	26
The basement membrane in the cross-roads between the lung and kidney	25
Hyaluronan synthase 3 is protective after cardiac ischemia-reperfusion by preserving the T cell response	23
Ubiquitin conjugating enzymes in the regulation of the autophagy-dependent degradation pathway	23
Versican provides the provisional matrix for uterine spiral artery dilation and fetal growth	23
Analysis of extracellular matrix network dynamics in cancer using the MatriNet database	23
Mechanical loading is required for initiation of extracellular matrix deposition at the developing murine myotendinous junction	23
Heparanase 2 (Hpa2) attenuates tumor growth by inducing Sox2 expression	21
Mammary collagen is under reproductive control with implications for breast cancer	21
Matricellular proteins in atherosclerosis development	21
Collagen denaturation in the infarcted myocardium involves temporally distinct effects of MT1-MMP-dependent proteolysis and mechanical tension	20
Lack of the myotendinous junction marker col22a1 results in posture and locomotion disabilities in zebrafish	20
Optic neuropathy associated with TGFβ dysregulation in mice with a glaucoma-causative mutation of ADAMTS10	20
Ameloblastin and its multifunctionality in amelogenesis: A review	20

Thrombospondin-1 promotes mechanical stress-mediated ligamentum flavum hypertrophy through the TGFβ1/Smad3 signaling pathway	20
Fibrillin-1 G234D mutation in the hybrid1 domain causes tight skin associated with dysregulated elastogenesis and increased collagen cross-linking in mice	20
Combined genetic-pharmacologic inactivation of tightly linked ADAMTS proteases in temporally specific windows uncovers distinct roles for versican proteolysis and glypican-6 in cardiac development	19
LPA-induced expression of CCN2 in muscular fibro/adipogenic progenitors (FAPs): Unraveling cellular communication networks	19
Matrix stiffness increases energy efficiency of endothelial cells	18
Absence of TRIC-B from type XIV Osteogenesis Imperfecta osteoblasts alters cell adhesion and mitochondrial function – A multi-omics study	18
Editorial Board	18
Delayed inhibition of collagen deposition by targeting bone morphogenetic protein 1 promotes recovery after spinal cord injury	18
Aberrant TIMP-1 overexpression in tumor-associated fibroblasts drives tumor progression through CD63 in lung adenocarcinoma	18
Modulating tenascin-C functions by targeting the MAtrix REgulating MOtif, “MAREMO”	18
Cell differentiation and matrix organization are differentially affected during bone formation in osteogenesis imperfecta zebrafish models with different genetic defects impacting collagen type I stru	18
Activation of skeletal muscle FAPs by LPA requires the Hippo signaling via the FAK pathway	18
Health consequences of mutant cartilage oligomeric matrix protein and its relationship to abnormal growth and joint degeneration	18
Targeting cellular stress in vitro improves osteoblast homeostasis, matrix collagen content and mineralization in two murine models of osteogenesis imperfecta	17
Increased expression of the pathological O-glycosylated form of oncofetal fibronectin in the multidrug resistance phenotype of cancer cells	16
Autocrine IL-6 drives cell and extracellular matrix anisotropy in scar fibroblasts	16
Role of autophagy in intervertebral disc and cartilage function: implications in health and disease	16
ADAMTS6 cleaves the large latent TGFβ complex and increases the mechanotension of cells to activate TGFβ	16
Induction of heparanase 2 (Hpa2) expression by stress is mediated by ATF3	16
O-fucosylation of thrombospondin type 1 repeats is essential for ECM remodeling and signaling during bone development	16
Chemotherapy treatment induces pro-invasive changes in liver ECM composition	15
Tenascin-C targeting strategies in cancer	15
Toward a rational therapeutic for elastin related disease: key considerations for elastin based regenerative medicine strategies	15
Editorial Board	14
Remodeling of the extracellular matrix by serine proteases as a prerequisite for cancer initiation and progression	14
Unraveling the role of TGFβ signaling in thoracic aortic aneurysm and dissection using Fbn1 mutant mouse models	14
Shed syndecan-2 enhances colon cancer progression by increasing cooperative angiogenesis in the tumor microenvironment	14
Endothelial cell (EC)-specific Ctgf/Ccn2 expression increases EC reprogramming and atherosclerosis	14
What does it take to be a collagen receptor?	14
Heparan sulfate dependent binding of plasmatic von Willebrand factor to blood circulating melanoma cells attenuates metastasis	14
Beyond the matrisome: New frontiers in ECM research	14
Role of syndecan-4 in angiogenesis and vasculogenic mimicry in triple negative breast cancer cells	13
An adapted passive model of anti-MPO dependent crescentic glomerulonephritis reveals matrix dysregulation and is amenable to modulation by CXCR4 inhibition	13
Degradomics technologies in matrisome exploration	13
The C-type lectin CD93 controls endothelial cell migration via activation of the Rho family of small GTPases	13
The phosphorylation of serine55 in enamelin is essential for murine amelogenesis	13
Heparanase 2 (Hpa2) attenuates the growth of pancreatic carcinoma	13
Putting the brakes on autophagy: The role of heparan sulfate modified proteins in the balance of anabolic and catabolic pathways and intracellular quality control	13
Matrix-bound Cyr61/CCN1 is required to retain the properties of the bone marrow mesenchymal stem cell niche but is depleted with aging	13
Endothelial hyaluronan synthase 3 aggravates acute colitis in an experimental model of inflammatory bowel disease	13
Neurocan regulates axon initial segment organization and neuronal activity	13
Obesity impairs skeletal muscle repair through NID-1 mediated extracellular matrix remodeling by mesenchymal progenitors	13
Corneal fibroblast collagen type IV negative feedback modulation of TGF beta: A fibrosis modulating system likely active in other organs	13
Corrigendum to “Syndecan-1 shedding by meprin β impairs keratinocyte adhesion and differentiation in hyperkeratosis”	13
Vertebrate extracellular matrix protein hemicentin-1 interacts physically and genetically with basement membrane protein nidogen-2	13
ECM-regulation of autophagy: The yin and the yang of autophagy during wound healing	12
The dynamic kidney matrisome - is the circadian clock in control?	12
Loss of Hs3st3a1 or Hs3st3b1 enzymes alters heparan sulfate to reduce epithelial morphogenesis and adult salivary gland function	12
Myeloid deficiency of heparan sulfate 6-O-endosulfatases impairs bone marrow hematopoiesis	12
Tumor and stroma COL8A1 secretion induces autocrine and paracrine progression signaling in pancreatic ductal adenocarcinoma	12

Targeting the αVβ3/NgR2 pathway in neuroendocrine prostate cancer	12
AβPP-tau-HAS1 axis trigger HAS1-related nuclear speckles and gene transcription in Alzheimer's disease	12
Transglutaminase-mediated stiffening of the glomerular basement membrane mitigates pressure-induced reductions in molecular sieving coefficient by reducing compression	12
Novel insights into the role of Discoidin domain receptor 2 (DDR2) in cancer progression: a new avenue of therapeutic intervention	12
Regulation of the collagen IV network by the basement membrane protein perlecan is crucial for squamous epithelial cell morphogenesis and organ architecture	12
OSCC-derived EVs educate fibroblasts and remodel collagen landscape	12
Extracellular matrix integrity regulates GABAergic plasticity in the hippocampus	11
COL8A2 activation enhances function of corneal endothelial cells through HIPPO signaling/mitochondria pathway	11
Cleavage of Cartilage Oligomeric Matrix Protein (COMP) by ADAMTS4 generates a neoepitope associated with osteoarthritis and other forms of degenerative joint disease	11
Impact of vascular Ehlers-Danlos Syndrome-associated Gly substitutions on structure, function, and mechanics using bacterial collagen	11
Autophagy in the mesh of collagen VI	11
Tissue inhibitors of metalloproteinases are proteolytic targets of matrix metalloproteinase 9	11
Mechanistic interrogation of mutation-independent disease modulators of RDEB identifies the small leucine-rich proteoglycan PRELP as a TGF-β antagonist and inhibitor of fibrosis	10
Inter-alpha-trypsin inhibitor (IαI) and hyaluronan modifications enhance the innate immune response to influenza virus in the lung	10
A top-down approach to uncover the hidden ligandome of low-density lipoprotein receptor-related protein 1 in cartilage	10
Scleraxis and collagen I expression increase following pilot isometric loading experiments in a rodent model of patellar tendinopathy	10
The extracellular matrix – immune microenvironment crosstalk in cancer therapy: Challenges and opportunities	10
Collagen XVIII regulates extracellular matrix integrity in the developing nephrons and impacts nephron progenitor cell behavior	9
Hyperglycemic environments directly compromise intestinal epithelial barrier function in an organoid model and hyaluronan (∼35 kDa) protects via a layilin dependent mechanism	9
Identification of Periostin as a critical niche for myofibroblast dynamics and fibrosis during tendon healing	9
Tissue-specific collagen hydroxylation at GEP/GDP triplets mediated by P4HA2	9
Collagen VI deposition mediates stromal T cell trapping through inhibition of T cell motility in the prostate tumor microenvironment	9
Schwann cells contribute to keloid formation	9
Matrix stiffening facilitates the collective invasion of breast cancer through the periostin-integrin mechanotransduction pathway	9
The extracellular matrix differentially directs myoblast motility and differentiation in distinct forms of muscular dystrophy	9
Collagen VIII in vascular diseases	9
Accumulation of versican and lack of versikine ameliorate acute colitis	9
Kindler epidermolysis bullosa-like skin phenotype and downregulated basement membrane zone gene expression in poikiloderma with neutropenia and a homozygous USB1 mutation	8
My scientific journey to and through extracellular matrix	8
Emilin2 fosters vascular stability by promoting pericyte recruitment	8
TSG6 hyaluronan matrix remodeling dampens the inflammatory response during colitis	8
The cochlear matrisome: Importance in hearing and deafness	8
Systematic Analysis of Actively Transcribed Core Matrisome Genes Across Tissues and Cell Phenotypes	8
EMILIN-1 deficiency promotes chronic inflammatory disease through TGFβ signaling alteration and impairment of the gC1q/α4β1 integrin interaction	8
Editorial Board	8
Activation of the ATX/LPA/LPARs axis induces a fibrotic response in skeletal muscle	8
Elevated TGFβ signaling contributes to cerebral small vessel disease in mouse models of Gould syndrome	8
Effects of hydrostatic pressure, osmotic pressure, and confinement on extracellular matrix associated responses in the nucleus pulposus cells ex vivo	7
ADAM15 is required for optimal collagen cross-linking and scar formation following myocardial infarction	7
Nanoscale characterization of collagen structural responses to in situ loading in rat Achilles tendons	7
SEMA7a primes integrin α5β1 engagement instructing fibroblast mechanotransduction, phenotype and transcriptional programming	7
The epidermal integrin-mediated secretome regulates the skin microenvironment during tumorigenesis and repair	7
Hyaluronan degradation by HYAL2 is essential for odontoblastic differentiation and migration of mouse dental papilla cells	7
Matrisome alterations in obesity – Adipose tissue transcriptome study on monozygotic weight-discordant twins	7
A role for decorin in improving motor deficits after traumatic brain injury	7
Macrophage phenotype is determinant for fibrosis development in keloid disease	7
Interleukin-1α inhibits transforming growth factor-β1 and β2-induced extracellular matrix production, remodeling and signaling in human lung fibroblasts: Master regulator in lung mucosal repair	7
Role of amelogenin phosphorylation in regulating dental enamel formation	7
Collagen prolyl 4-hydroxylase isoenzymes I and II have sequence specificity towards different X-Pro-Gly triplets	7
PAD2-mediated citrullination of Fibulin-5 promotes elastogenesis	7
Age related changes in hyaluronan expression leads to Meibomian gland dysfunction	7
Molecular and epigenetic ex vivo profiling of testis cancer-associated fibroblasts and their interaction with germ cell tumor cells and macrophages	7
Corrigendum to “Fibrolamellar carcinomas–growth arrested by paracrine signals complexed with synthesized 3-O sulfated heparan sulfate oligosaccharides” [Matrix Biology 121(August 2023), 194–216]	6
Integrins and integrin-driven secretory pathways as multi-dimensional regulators of tumor-associated macrophage recruitment and reprogramming in tumor microenvironment	6
Fiber alignment in 3D collagen networks as a biophysical marker for cell contractility	6
Modulation of the expression and activity of cathepsin S in reconstructed human skin by neohesperidin dihydrochalcone	6
Fibrillin-1 regulates white adipose tissue development, homeostasis, and function	6
S100A4 a classical DAMP as a therapeutic target in fibrosis	6
Using load to improve tendon/ligament tissue engineering and develop novel treatments for tendinopathy	6
Myocardial fibrosis from the perspective of the extracellular matrix: Mechanisms to clinical impact	6
Temporally and spatially regulated collagen XVIII isoforms are involved in ureteric tree development via the TSP1-like domain	6
Syndecan-1 shedding by meprin β impairs keratinocyte adhesion and differentiation in hyperkeratosis	6
CCBE1 promotes mitochondrial fusion by inhibiting the TGFβ-DRP1 axis to prevent the progression of hepatocellular carcinoma	6
Corrigendum to “Regulation of extracellular matrix degradation and metastatic spread by IQGAP1 through endothelin-1 receptor signalling in ovarian cancer” [Matrix Biol. 81 (2019) 17-33]	6
Human intestinal myofibroblasts deposited collagen VI enhances adhesiveness for T cells – A novel mechanism for maintenance of intestinal inflammation	6
Editorial Board	5
Editorial Board	5
Autophagy: Instructions from the extracellular matrix	5
Substrate stiffness regulates the recurrent glioblastoma cell morphology and aggressiveness	5
Tumor-associated fibrosis impairs the response to immunotherapy	5
Suppression of OGN in lung myofibroblasts attenuates pulmonary fibrosis by inhibiting integrin αv-mediated TGF-β/Smad pathway activation	5
Loss of 3-O-sulfotransferase enzymes, Hs3st3a1 and Hs3st3b1, reduces kidney and glomerular size and disrupts glomerular architecture	5
Functional transfer of integrin co-receptor CD98hc by small extracellular vesicles improves wound healing in vivo	5
Inhibiting JAK1, not NF-κB, reverses the effect of pro-inflammatory cytokines on engineered human ligament function	5
A functional outside-in signaling network of proteoglycans and matrix molecules regulating autophagy	5
Type V collagen regulates the structure and biomechanics of TMJ condylar cartilage: A fibrous-hyaline hybrid	5
Coordination of two kinesin superfamily motor proteins, KIF3A and KIF13A, is essential for pericellular matrix degradation by membrane-type 1 matrix metalloproteinase (MT1-MMP) in cancer cells	5
35k Da specific-sized hyaluronan ameliorates high-fat diet-induced liver injury in murine model of moderate obesity	5
Editorial Board	5
CaMKII inhibition due to TRIC-B loss-of-function dysregulates SMAD signaling in osteogenesis imperfecta	5

Cysteine-rich domain of type III collagen N-propeptide inhibits fibroblast activation by attenuating TGFβ signaling	5
The role of positional information in determining dermal fibroblast diversity	5
AGEing of collagen: The effects of glycation on collagen’s stability, mechanics and assembly	5