OOIR: Observatory of International Research

Papers

(The TQCC of International Journal of Clinical Pharmacology and Therapeutics is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
Search for nutritional and inflammatory marker ratios to predict neutropenia in FEC therapy for breast cancer: A retrospective observational study	29
Adverse reaction profile of sulfasalazine and its persistence in chronic therapy of rheumatoid arthritis and spondyloarthritis: A multicentric observational study	20
A decision tree model for predicting high mono-N-desethylamiodarone concentrations and reducing tissue toxicity in patients with low-dose amiodarone therapy: A multicentral retrospective cohort study	11
Activated charcoal helps in the diagnosis of dabigatran overdose: A case study	10
Comparison of the efficacy and safety of tofacitinib and mavrilimumab in patients with active rheumatoid arthritis: A Bayesian network meta-analysis of randomized controlled trials	9
Association between ABCB1 C3435T polymorphism and antiepileptic drug resistance in epilepsy: An updated meta-analysis based on 62 studies	8
Post-marketing safety concerns with montelukast: A pharmacovigilance study based on the FDA adverse event reporting system	7
Potential drug-drug interactions in a multi-center study of death cases of COVID-19: The significance of appropriate drug choice	7
A cross-sectional study on the potential drug-drug interaction risk of COVID-19 patients in hospital	7
Research progress in targeted therapies for gastric cancer	7
Drug-induced hepatotoxicity linked to zoledronic acid in the treatment of an elderly man with primary osteoporosis	6
Rare systemic skin hyperpigmentation associated with osimertinib: A case report	6
Adverse event profiles of drugs used for treatment of juvenile idiopathic arthritis according to spontaneous reporting system database	6
Cabotegravir pharmacokinetics in Asian population with and without HIV	6
Network pharmacology analysis and clinical efficacy of the traditional Chinese medicine Bu-Shen-Jian-Pi. Part 2: Modulation of hypoxia, redox status, and mitochondrial protection in a neuroblastoma ce	6
Severe drug-induced immune hemolytic anemia due to cefmetazole: A case report	5
Interferon α-induced lupus-like reaction in a mycosis fungoides patient: A case report	5
Factors affecting outcome in hospitalized patients treated according to recommendations from clinical pharmacologists	5
Effects of iguratimod in the treatment of palindromic rheumatism: Case report	5
Retrospective evaluation of medical information for predicting tazobactam/piperacillin-induced liver injury	5
Cost-utility analysis of pembrolizumab versus nivolumab in the treatment of metastatic colorectal cancer from the perspective of the healthcare payer	5
Self-reported urinary urgency in association with vitamin D and psychiatric symptoms among patients with musculoskeletal pain	5
Drug-drug interaction between remdesivir and immunosuppressant agents in a kidney transplant recipient	5
Deprescribing proton pump inhibitors: A study in hospitalized patients in Slovenia	4
Sodium-glucose cotransporter-2 inhibitor treatment has differential effects on the incidence of various malignancies: Evidence from a spontaneous adverse reaction database	4

Pegylated-interferon alpha (PEG-IFNα)-induced interstitial lung disease in a patient with chronic hepatitis B: A case report and literature review	4
Prevalence of and factors associated with the prescription of phytopharmaceuticals in outpatients with urinary tract infections	4
Methylobacterium infection-induced peritonitis in a patient with renal insufficiency: A case report and literature review	4
Components in Prunus mume and their targets in the alleviation of severe depression identified using network pharmacology analysis	4
Safety profile of carbapenems: Data mining of the FDA adverse events reporting system	4
Potentiation of paclitaxel-induced apoptosis in a non-small cell lung cancer model using the traditional Chinese drug huaier: Network pharmacology analysis, experimental verification, and clinical imp	4
Comparison of the efficacy and safety of tocilizumab, sarilumab, and sirukumab in comparison with adalimumab as monotherapy in patients with active rheumatoid arthritis: A Bayesian network meta-analys	3
COVID-19 pandemic management using the 14-day projected incidence	3
Randomized, open-label, crossover trial comparing the pharmacokinetic profile of a novel oral aspirin solution and a chewed aspirin tablet	3
Warfarin pharmacokinetics and pharmacodynamics are not affected by concomitant administration of the long-acting GLP-1 receptor agonist polyethylene glycol loxenatide	3
Securing a diagnosis in patients presenting with suspected paracetamol (acetaminophen) poisoning: A retrospective cohort study	3
Bioequivalence study of two formulations of afatinib dimaleate tablets in healthy subjects under fasting conditions: A randomized, open-label, single-dose, crossover trial	3
Evaluation of the risk factors for the failure of a single prophylactic dose of anticholinergic drugs for irinotecan-induced cholinergic symptoms	3
Pharmacokinetics and bioequivalence study of two ciprofloxacin hydrochloride tablets in healthy Chinese subjects under fasting and fed conditions: A randomized, open-label, two-formulation, two-sequen	3
Pharmacokinetics, safety, and bioequivalence of apixaban tablets in healthy Chinese subjects under fasting and fed conditions	3
Degree of serum LDL cholesterol reduction by simvastatin and ezetimibe is dependent on baseline LDL cholesterol concentration but not on baseline values and changes in cholesterol synthesis and absorp	3
Sub-therapeutic trimethoprim and sulfamethoxazole plasma concentrations during continuous venovenous hemofiltration in a patient with COVID-19 and pulmonary Pneumocystis jirovecii co-infection: A case	3
Severe genital cutaneous toxicity with sunitinib	3
Simultaneous determination of cefmetazole and cefaclor in urine from pediatric patients with urinary tract infections using a newly developed high-performance liquid chromatography assay method	3
Pharmacokinetic evaluation and relative bioavailability pilot study of fidaxomicin in healthy Chinese subjects: An open, randomized, single-dose, cross-over study	3
Tocilizumab: A retrospective multi-center cohort study of critically ill patients with COVID-19	3
Elevation of serum creatine kinase induced by anti-thyroid drugs: Two case reports and a literature review	3
Bleeding events associated with recombinant human soluble thrombomodulin, classified according to renal function, in sepsis-induced disseminated intravascular coagulation	3
Comparative efficacy and safety of topiroxostat at different dosages in hyperuricemic patients with or without gout: A network meta-analysis of randomized controlled trials	3
Metformin alone and in combination with sitagliptin induces depression and impairs quality of life in type 2 diabetes mellitus patients: An observational study	3
The vancomycin dosage calculator: Prediction superiority and validation in a comparison of four algorithms using retrospective data from non-critical patients aged 18 to 59 years	3
Pharmacokinetics and pharmacodynamics of amiodarone in patients with hypertriglyceridemia: Two case reports	3
High-dose ulinastatin reduces postoperative bleeding and provides platelet-protective effects in patients undergoing heart valve replacement surgery	3
Aplastic anemia associated with osimertinib: Analysis of the FDA adverse event reporting system	3
Imipenem cilastatin sodium-associated thrombocytopenia in an older patient: A case report and literature review	3
Activated charcoal can be used to aid the diagnosis of an overdose of dabigatran etexilate	3
Bioavailability study of Enoxaparin Sodium Chemi (80 mg/0.8 mL) and Clexane (80 mg/0.8 mL) subcutaneous injection in healthy adults	2
Bisphosphonates in combination with alendronate sodium increase bone mineral density and modulate IL-6, TNF-α, and IGF-1 in patients with osteoporosis	2
Hypersensitivity reaction to high-dose methotrexate and methotrexate-induced acral erythema in a child with acute lymphoblastic leukemia	2
Early acute kidney injury after tacrolimus administration in heart transplant recipients receiving basiliximab induction therapy	2
Longevity – via traditional Chinese medicine and macrobiotics to AI-driven network pharmacology and clinical pharmacology	2
Clinical Handbook of Psychotropic Drugs for Children and Adolescents (5th Edition)	2
Changes in the intestinal microbiota of patients with Parkinson’s disease and their clinical significance	2
A pharmacokinetic analysis of amisulpride in adult Chinese patients with schizophrenia: Impact of creatinine clearance	2
The International Journal of Clinical Pharmacology and Therapeutics: Medical-scientific publishing tradition with adaptability, innovation, and momentum	2
Analgesia with reduced incidence of adverse reactions using flurbiprofen axetil in combination with half standard-dose opioids in primary total knee arthroplasty	2
Treatment of severe psoriasis in a hospice care patient using secukinumab, an inhibitor of interleukin-17A expression: Treatment response and changes in quality of life	2
Severe autoimmune hemolytic anemia associated with glucose-6-phosphate dehydrogenase deficiency as a complication of nivolumab treatment: A case report	2
Pharmacokinetic and bioequivalence of lenalidomide in multiple myeloma patients	2
Risks of malignant lymphoma in rheumatoid arthritis patients receiving methotrexate-alone and in combination therapy compared with the general population: A study based on a Japanese medical claims da	2
Sodium-glucose cotransporter 2 (SGLT2) inhibitors, as potential (off-label) anti-obesity agents and effects on cardiovascular risk: A systematic review and meta-analysis	2
Ocular myasthenia gravis-like symptoms associated with erenumab: Case report	2
Comparative efficacy and safety of etanercept biosimilars in comparison with etanercept in patients with rheumatoid arthritis who have insufficient response to methotrexate: A network meta-analysis	2
Evaluation of the comparative pharmacokinetic properties of a new orally disintegrating tablet of tegoprazan in healthy Korean subjects	2
Neonatal pain score after use of paracetamol: Is there a relationship with serum trough concentration at steady state in preterm and term neonates?	2

Can a β-glucan-containing orthomolecular agent (Saccharomyces sp.) containing metabolic cofactors attenuate cytokine activation and alleviate hypoxia in COVID-19 patients?	2
Is compressed colchicine tablet superior to other colchicine preparations in patients with familial Mediterranean fever?	2
Network target theory and network pharmacology: Next generation drug research in medicine using AI models	2
Clinical effects of atomizing inhalation of antibiotics on germ clearance rate and adverse reactions in respiratory infectious diseases: A meta-analysis	2
Intrathecal drug-infusion system for treating pain in advanced cancer: New research in patient management	2
Pharmacokinetics and bioequivalence of tofacitinib 5 mg in healthy Korean male subjects	2
Successful management of tumor necrosis factor-alpha inhibitor-induced Sweet syndrome in a patient with ulcerative colitis: A case report	2
Association of gynecomastia with antidiabetic medications in older adults: Data mining from different national pharmacovigilance databases	2
Differentiation of bone marrow mesenchymal stem cells modulated by Bushen Tian Sui decoction via the TGF-β1-Smad2/3 signaling pathway: In vitro evidence and potential clinical application in delayed f	2
Latent class analysis of patients’ background factors affecting the risk of specific adverse drug reactions to dipeptidyl peptidase 4 inhibitors	2
Prevalence of therapeutic drug monitoring and adherence to imatinib in chronic myeloid leukemia in Japan	2
Inotersen and severe thrombocytopenia: 2 case reports and review	2
Topics in focus 2025 The International Journal of Clinical Pharmacology and Therapeutics	2
Analysis of risk factors for hypoglycemia in patients with gastrointestinal bleeding induced by somatostatin for injection and establishment of the prediction model	2
Improving the long-term response to antidepressants by establishing an individualized platform based on variability and chronotherapy	2