OOIR: Observatory of International Research

Papers

(The TQCC of International Journal of Clinical Pharmacology and Therapeutics is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Search for nutritional and inflammatory marker ratios to predict neutropenia in FEC therapy for breast cancer: A retrospective observational study	15
Activated charcoal helps in the diagnosis of dabigatran overdose: A case study	13
Rare systemic skin hyperpigmentation associated with osimertinib: A case report	10
Post-marketing safety concerns with montelukast: A pharmacovigilance study based on the FDA adverse event reporting system	9
Potential drug-drug interactions in a multi-center study of death cases of COVID-19: The significance of appropriate drug choice	8
A decision tree model for predicting high mono-N-desethylamiodarone concentrations and reducing tissue toxicity in patients with low-dose amiodarone therapy: A multicentral retrospective cohort study	8
Cabotegravir pharmacokinetics in Asians with and without HIV	8
A cross-sectional study on the potential drug-drug interaction risk of COVID-19 patients in hospital	8
Integrative treatment of the motor neuron disease amyotrophic lateral sclerosis, efficacy of pharmacotherapy, traditional Chinese medicine and importance of respiratory support, life-style, and gastro	8
Research progress in targeted therapies for gastric cancer	8
Inflammatory cytokines, autoantibodies and salivary gland function in Sjögren’s syndrome: Effects of T. wilfordii as Hook F medical wine and Tripterygium glycosides tablets	7
Adverse event profiles of drugs used for treatment of juvenile idiopathic arthritis according to spontaneous reporting system database	7
Adverse reaction profile of sulfasalazine and its persistence in chronic therapy of rheumatoid arthritis and spondyloarthritis: A multicentric observational study	7
Effects of iguratimod in the treatment of palindromic rheumatism: Case report	7
Retrospective evaluation of medical information for predicting tazobactam/piperacillin-induced liver injury	6
Sodium-glucose cotransporter-2 inhibitor treatment has differential effects on the incidence of various malignancies: Evidence from a spontaneous adverse reaction database	6
Methylobacterium infection-induced peritonitis in a patient with renal insufficiency: A case report and literature review	6
Interferon α-induced lupus-like reaction in a mycosis fungoides patient: A case report	6
Cost-utility analysis of pembrolizumab versus nivolumab in the treatment of metastatic colorectal cancer from the perspective of the healthcare payer	6
Pegylated-interferon alpha (PEG-IFNα)-induced interstitial lung disease in a patient with chronic hepatitis B: A case report and literature review	5
The Enhanced Games with doping permitted and Hulk Hogan	5
Factors affecting outcome in hospitalized patients treated according to recommendations from clinical pharmacologists	5
Personalized management of acenocoumarol dosage using eGFR: Analysis of INR data in a cohort of 204 patients	5
Potentiation of paclitaxel-induced apoptosis in a non-small cell lung cancer model using the traditional Chinese drug huaier: Network pharmacology analysis, experimental verification, and clinical imp	5
Self-reported urinary urgency in association with vitamin D and psychiatric symptoms among patients with musculoskeletal pain	5

Drug-drug interaction between remdesivir and immunosuppressant agents in a kidney transplant recipient	5
Elevation of serum creatine kinase induced by anti-thyroid drugs: Two case reports and a literature review	4
Bleeding events associated with recombinant human soluble thrombomodulin, classified according to renal function, in sepsis-induced disseminated intravascular coagulation	4
Prediction of anti-epileptic drug response of patients based on peripheral blood RNA profiles and machine learning	4
Acute arsenic poisoning from realgar water: Case series from Guilin, China	4
Sub-therapeutic trimethoprim and sulfamethoxazole plasma concentrations during continuous venovenous hemofiltration in a patient with COVID-19 and pulmonary Pneumocystis jirovecii co-infection: A case	4
Pharmacokinetics, safety, and bioequivalence of apixaban tablets in healthy Chinese subjects under fasting and fed conditions	4
Network pharmacology analysis and clinical efficacy of the traditional Chinese medicine Bu-Shen-Jian-Pi. Part 2: Modulation of hypoxia, redox status, and mitochondrial protection in a neuroblastoma ce	4
Evaluation of the risk factors for the failure of a single prophylactic dose of anticholinergic drugs for irinotecan-induced cholinergic symptoms	4
High-dose ulinastatin reduces postoperative bleeding and provides platelet-protective effects in patients undergoing heart valve replacement surgery	4
Metformin alone and in combination with sitagliptin induces depression and impairs quality of life in type 2 diabetes mellitus patients: An observational study	4
Components in Prunus mume and their targets in the alleviation of severe depression identified using network pharmacology analysis	4
Activated charcoal can be used to aid the diagnosis of an overdose of dabigatran etexilate	4
Degree of serum LDL cholesterol reduction by simvastatin and ezetimibe is dependent on baseline LDL cholesterol concentration but not on baseline values and changes in cholesterol synthesis and absorp	4
Imipenem cilastatin sodium-associated thrombocytopenia in an older patient: A case report and literature review	4
Aplastic anemia associated with osimertinib: Analysis of the FDA adverse event reporting system	4
Pharmacokinetic evaluation and relative bioavailability pilot study of fidaxomicin in healthy Chinese subjects: An open, randomized, single-dose, cross-over study	4
Deprescribing proton pump inhibitors: A study in hospitalized patients in Slovenia	4
Randomized, open-label, crossover trial comparing the pharmacokinetic profile of a novel oral aspirin solution and a chewed aspirin tablet	3
Simultaneous determination of cefmetazole and cefaclor in urine from pediatric patients with urinary tract infections using a newly developed high-performance liquid chromatography assay method	3
Warfarin pharmacokinetics and pharmacodynamics are not affected by concomitant administration of the long-acting GLP-1 receptor agonist polyethylene glycol loxenatide	3
Severe autoimmune hemolytic anemia associated with glucose-6-phosphate dehydrogenase deficiency as a complication of nivolumab treatment: A case report	3
Hypersensitivity reaction to high-dose methotrexate and methotrexate-induced acral erythema in a child with acute lymphoblastic leukemia	3
Pharmacokinetic and bioequivalence of lenalidomide in multiple myeloma patients	3
Bioequivalence study of two formulations of afatinib dimaleate tablets in healthy subjects under fasting conditions: A randomized, open-label, single-dose, crossover trial	3
Severe genital cutaneous toxicity with sunitinib	3
Semaglutide-induced transient intestinal ischemia: A case report	3
Treatment of severe psoriasis in a hospice care patient using secukinumab, an inhibitor of interleukin-17A expression: Treatment response and changes in quality of life	3
Network target theory and network pharmacology: Next generation drug research in medicine using AI models	3
The vancomycin dosage calculator: Prediction superiority and validation in a comparison of four algorithms using retrospective data from non-critical patients aged 18 to 59 years	3
Pharmacokinetics and pharmacodynamics of amiodarone in patients with hypertriglyceridemia: Two case reports	3
Intrathecal drug-infusion system for treating pain in advanced cancer: New research in patient management	3
Clinical effects of atomizing inhalation of antibiotics on germ clearance rate and adverse reactions in respiratory infectious diseases: A meta-analysis	3
Analgesia with reduced incidence of adverse reactions using flurbiprofen axetil in combination with half standard-dose opioids in primary total knee arthroplasty	3
A randomized, double-blind, three-arm, parallel group, single-dose phase I study to evaluate the pharmacokinetic similarity between SB12 (a proposed eculizumab biosimilar) and eculizumab (Soliris) in	2
Acute myeloid leukemia after 10 years of azathioprine treatment for Crohn’s disease	2
Clinical Handbook of Psychotropic Drugs for Children and Adolescents (5th Edition)	2
Changes in the intestinal microbiota of patients with Parkinson’s disease and their clinical significance	2
Pegylated liposomal doxorubicin-induced hand-foot syndrome in a patient with breast cancer: Case report and FAERS database analysis	2
Differentiation of bone marrow mesenchymal stem cells modulated by Bushen Tian Sui decoction via the TGF-β1-Smad2/3 signaling pathway: In vitro evidence and potential clinical application in delayed f	2
Effect of inhaled corticosteroid with oral montelukast and levocetirizine in asthma: A population-based study	2
Bisphosphonates in combination with alendronate sodium increase bone mineral density and modulate IL-6, TNF-α, and IGF-1 in patients with osteoporosis	2
Exogenous insulin antibody syndrome in type 2 diabetes with diabetic ketoacidosis: A case report and literature review	2
Risks of malignant lymphoma in rheumatoid arthritis patients receiving methotrexate-alone and in combination therapy compared with the general population: A study based on a Japanese medical claims da	2
Adenosine-2A agonists: Positioning as functional contrast agents in diagnostic cardiology	2
A pharmacokinetic analysis of amisulpride in adult Chinese patients with schizophrenia: Impact of creatinine clearance	2
Comparison of the acid suppression effects between low-dose esomeprazole and famotidine in healthy subjects	2
Subcutaneous infliximab CT-P13 without intravenous induction in psoriatic arthritis: A case report and pharmacokinetic considerations	2
Ocular myasthenia gravis-like symptoms associated with erenumab: Case report	2
Beneficial effects of dexmedetomidine with sevoflurane inhalation in abdominal surgery: Quality of anesthesia, intestinal flora, and serum pain mediators	2

Can a β-glucan-containing orthomolecular agent (Saccharomyces sp.) containing metabolic cofactors attenuate cytokine activation and alleviate hypoxia in COVID-19 patients?	2
Evaluation of the comparative pharmacokinetic properties of a new orally disintegrating tablet of tegoprazan in healthy Korean subjects	2
Epithelial-mesenchymal transition biomarkers in patients with acute exacerbation of COPD are indicative of disease severity, disease progression, and risk of readmission	2
Is compressed colchicine tablet superior to other colchicine preparations in patients with familial Mediterranean fever?	2
Topics in focus 2025 The International Journal of Clinical Pharmacology and Therapeutics	2
Analysis of risk factors for hypoglycemia in patients with gastrointestinal bleeding induced by somatostatin for injection and establishment of the prediction model	2
Latent class analysis of patients’ background factors affecting the risk of specific adverse drug reactions to dipeptidyl peptidase 4 inhibitors	2
Longevity – via traditional Chinese medicine and macrobiotics to AI-driven network pharmacology and clinical pharmacology	2
Hemoglobin A1c levels in patients with type 2 diabetes mellitus receiving oral semaglutide with versus without proton pump inhibitors: An exploratory study	2
Treatment of delayed fracture healing with Bushen Tiansui decoction: Analysis of active agents and targets using bioinformatics and network pharmacology analysis	2
Early acute kidney injury after tacrolimus administration in heart transplant recipients receiving basiliximab induction therapy	2
Adverse reactions of PD-1/PD-L1 inhibitors in cancer: FAERS database analysis and protocols to mitigate immune-related events in elderly patients and when using pembrolizumab and atezolizumab	2
Prevalence of therapeutic drug monitoring and adherence to imatinib in chronic myeloid leukemia in Japan	2
Neonatal pain score after use of paracetamol: Is there a relationship with serum trough concentration at steady state in preterm and term neonates?	2
Evaluating real-world data in COVID-19 antigen and PCR testing	2
A rare case of septic shock caused by Serratia marcescens in an immunocompetent male adolescent. Comment on: DOI: 10.5414/CP204652 by Mughrab et al.	2
Pharmacokinetics and bioequivalence of tofacitinib 5 mg in healthy Korean male subjects	2
Inotersen and severe thrombocytopenia: 2 case reports and review	2
Sodium-glucose cotransporter 2 (SGLT2) inhibitors, as potential (off-label) anti-obesity agents and effects on cardiovascular risk: A systematic review and meta-analysis	2
Network pharmacology and bioinformatics analysis of the multi-target immune-inflammatory mechanisms of Shengma Gegen decoction in chronic urticaria	2