Journal of Molecular Medicine-Jmm

Article	Citations
The molecular and cellular landscape of hypertrophic cardiomyopathy phenotypes: transition from obstructive to end-stage heart failure	77
Kat7 accelerates osteoarthritis disease progression through the TLR4/NF-κB signaling pathway	68
Soluble LDL-receptor is induced by TNF-α and inhibits hepatocytic clearance of LDL-cholesterol	67
Metabolomics reveals that chronic restraint stress alleviates carbon tetrachloride-induced hepatic fibrosis through the INSR/PI3K/AKT/AMPK pathway	64
Eucalyptol induces osteoblast differentiation through ERK phosphorylation in vitro and in vivo	62
Retraction Note: Endothelin-1 induces the transactivation of vascular endothelial growth factor receptor-3 and modulates cell migration and vasculogenic mimicry in melanoma cells	60
Glycosylation is a key in SARS-CoV-2 infection	58
Mitochondrial transplantation as a possible therapeutic option for sarcopenia	55
The role of CD146 in renal disease: from experimental nephropathy to clinics	50
Acid sphingomyelinase expression is associated with survival in resectable pancreatic ductal adenocarcinoma	48
Sex hormone binding globulin (SHBG) modulates mitochondrial dynamics in PPARγ-depleted equine adipose derived stromal cells	44
PCDH11X mutation as a potential biomarker for immune checkpoint therapies in lung adenocarcinoma	37
Protective role of M3 muscarinic acetylcholine receptor in indomethacin-induced small intestinal injury	36
Removal of GIT lesions and the role of impedance of the injection solution—an innovative approach to known methods	35
Analysis of the action mechanisms and targets of herbal anticonvulsants highlights opportunities for therapeutic engagement with refractory epilepsy	34
The mutual interplay of redox signaling and connexins	34
I536T variant of RBM20 affects splicing of cardiac structural proteins that are causative for developing dilated cardiomyopathy	33
A novel ceRNA regulatory network involving the long noncoding NEAT1, miRNA-466f-3p and its mRNA target in osteoblast autophagy and osteoporosis	33
Nrf2 as a potential target for Parkinson’s disease therapy	33
X-linked genes exhibit skewed expression in Sjogren’s disease (SjD): a further step toward understanding the female predominance of autoimmune disease	30
Loss-of-function mutation in DDX53 associated with hereditary spastic paraplegia-like disorder	29
Pathogenic effects of Leu200Pro and Arg387His VRK1 protein variants on phosphorylation targets and H4K16 acetylation in distal hereditary motor neuropathy	29
IGFBP2 function as a novel biomarker for active lupus nephritis	29
Acyloxyacyl hydrolase deficiency induces chronic inflammation and bone loss in male mice	28
ABCB1 in dermatology: roles in skin diseases and their treatment	27

Histone modification in podocyte injury of diabetic nephropathy	27
WWOX and metabolic regulation in normal and pathological conditions	26
Unleashing the power of NK cells in anticancer immunotherapy	26
The CRL4DCAF6 E3 ligase ubiquitinates CtBP1/2 to induce apoptotic signalling and promote intervertebral disc degeneration	26
Correction to: The recurrent missense mutation p.(Arg367Trp) in YARS1 causes a distinct neurodevelopmental phenotype	26
Identification of STAT3 and MYC as critical ferroptosis-related biomarkers in septic cardiomyopathy: a bioinformatics and experimental study	25
Potential role of mesenchymal stem cells in T cell aging	25
Identification of the regulatory mechanism of ACE2 in COVID-19–induced kidney damage with systems genetics approach	24
Knockdown of SOX9 alleviates tracheal fibrosis through the Wnt/β-catenin signaling pathway	24
Increased Fusobacterium tumoural abundance affects immunogenicity in mucinous colorectal cancer and may be associated with improved clinical outcome	24
JAK2 regulates paclitaxel resistance in triple negative breast cancers	22
Diminished miR-374c-5p negatively regulates IL (interleukin)-6 in unexplained recurrent spontaneous abortion	21
Loss of CAA interruption and intergenerational CAG instability in Chinese patients with Huntington’s disease	21
Novel high-yield potato protease inhibitor panels block a wide array of proteases involved in viral infection and crucial tissue damage	21
X-linked genes exhibit miR6891-5p-regulated skewing in Sjögren’s syndrome	21
Post-infarction cardiac remodeling—differential biomarkers for left atrial and left ventricular remodeling	21
Correction to: The protean world of non-coding RNAs in glioblastoma	21
Silencing of Mcl-1 overcomes resistance of melanoma cells against TRAIL-armed oncolytic adenovirus by enhancement of apoptosis	21
A simple tool for evaluation of inflammation in psoriasis: Neutrophil-to-lymphocyte and platelet-to-lymphocyte ratio as markers in psoriasis patients and related murine models of psoriasis-like skin d	20
IL-23 contributes to Particulate Matter induced allergic asthma in the early life of mice and promotes asthma susceptibility	20
CD27 expression on Treg cells limits immune responses against tumors	20
Neurovascular abnormalities in retinopathy of prematurity and emerging therapies	20
The role of immunosuppressive myofibroblasts in the aging process and age-related diseases	20
Synthetic polypeptide crotamine: characterization as a myotoxin and as a target of combinatorial peptides	20
Suppression of PGE2/EP2 signaling alleviates Hirschsprung disease by upregulating p38 mitogen-activated protein kinase activity	19
Nets, pulmonary arterial hypertension, and thrombo-inflammation	19
The PER3rs772027021 SNP induces pigmentation phenotypes of dyschromatosis universalis hereditaria	19
Indole-3-Aldehyde alleviates lung inflammation in COPD through activating Aryl Hydrocarbon Receptor to inhibit HDACs/NF-κB/NLRP3 signaling pathways	19
Identification of PDXDC1 as a novel pleiotropic susceptibility locus shared between lumbar spine bone mineral density and birth weight	19
Correction to: The vasculature niches required for hematopoiesis	19
Sympathetic nerve-adipocyte interactions in response to acute stress	18
Advances in gene therapy for neurogenetic diseases: a brief review	18
The role and mechanism of heme oxygenase-1 in arrhythmias	17
Molecular mechanisms of thalidomide effectiveness on COVID-19 patients explained: ACE2 is a new ΔNp63α target gene	17
Preferential expression of SCN1A in GABAergic neurons improves survival and epileptic phenotype in a mouse model of Dravet syndrome	17
Effect of α7 nAChR-autophagy axis of deciduous tooth pulp stem cells in regulating IL-1β in the process of physiological root resorption of deciduous teeth	17
Nicotinamide riboside kinase-2 regulates metabolic adaptation in the ischemic heart	17
Soluble IL-6R-mediated IL-6 trans-signaling activation contributes to the pathological development of psoriasis	16
Longitudinal study on immunologic, lipoproteomic, and inflammatory responses indicates the safety of sequential COVID-19 vaccination	16
Biochemical and structural characterization of beta-carbonic anhydrase from the parasite Trichomonas vaginalis	16
The caspase-inhibitor Emricasan efficiently counteracts cisplatin- and neomycin-induced cytotoxicity in cochlear cells	16
Recent updates on targeting the molecular mediators of NAFLD	16
SAMHD1 in cancer: curse or cure?	15
Cellular localization of nucleolin determines the prognosis in cancers: a meta-analysis	15
Melatonin inhibits senescence-associated melanin pigmentation through the p53-TYR pathway in human primary melanocytes and the skin of C57BL/6 J mice after UVB irradiation	15
LMO3 reprograms visceral adipocyte metabolism during obesity	15
An innovative targeted therapy for fluoroscopy-induced chronic radiation dermatitis	15
PARP2 promotes inflammation in psoriasis by modulating estradiol biosynthesis in keratinocytes	15
Liquid–liquid phase separation in Alzheimer’s disease	15
PD-1/PD-L1 axis: implications in immune regulation, cancer progression, and translational applications	15

Multiple sclerosis is linked to MAPKERK overactivity in microglia	15
Gaucher disease – more than just a rare lipid storage disease	14
Mechanism of efferocytosis in atherosclerosis	14
Non-invasive biomarkers prognostic of decompensation events in NASH cirrhosis: a systematic literature review	14
Modelling of BCS1L-related human mitochondrial disease in Drosophila melanogaster	13
Exploring the role of tRNA-derived small RNAs (tsRNAs) in disease: implications for HIF-1 pathway modulation	13
Protective mechanisms of loquat leaf extract and ursolic acid against diabetic pro-inflammation	13
MyD88 in hepatic stellate cells promotes the development of alcoholic fatty liver via the AKT pathway	13
The role of regulated necrosis in diabetes and its complications	13
Novel insights into the nervous system affected by prolonged hyperglycemia	13
GSK-3α aggravates inflammation, metabolic derangement, and cardiac injury post-ischemia/reperfusion	12
The diagnostic potential of a circRNA–miRNA network in non-small cell lung cancer	12
Human colorectal cancer-associated carbohydrate antigen on annexin A2 protein	12
Etiopathogenesis of medication-related osteonecrosis of the jaws: a review	12
Apamin inhibits renal fibrosis via suppressing TGF-β1 and STAT3 signaling in vivo and in vitro	12
Dissecting the role of cell signaling versus CD8+ T cell modulation in propranolol antitumor activity	12
Inhibition of ERK/CREB signaling contributes to postoperative learning and memory dysfunction in neonatal rats	12
SMARCC1 promotes M2 macrophage polarization and reduces ferroptosis in lung cancer by activating FLOT1 transcription	12
Circular RNAs: regulators of vascular smooth muscle cells in cardiovascular diseases	12
Structure-based humanization of a therapeutic antibody for multiple myeloma	12
Aging- and alcohol-associated spatial transcriptomic signature in mouse acute pancreatitis reveals heterogeneity of inflammation and potential pathogenic factors	12
FATP1-mediated fatty acid uptake in renal tubular cells as a countermeasure for hypothermia	12
Metformin improves cognitive dysfunction through SIRT1/NLRP3 pathway–mediated neuroinflammation in db/db mice	11
The recurrent missense mutation p.(Arg367Trp) in YARS1 causes a distinct neurodevelopmental phenotype	11
Valproic acid modulates collagen architecture in the postoperative conjunctival scar	11
Aquaporin-4 prevents exaggerated astrocytosis and structural damage in retinal inflammation	11
LAMP2A regulates the balance of mesenchymal stem cell adipo-osteogenesis via the Wnt/β-catenin/GSK3β signaling pathway	11
The oncogenic role of EIF4A3/CDC20 axis in the endometrial cancer	11
Modulation of cellular transcriptome and proteome composition by azidohomoalanine—implications on click chemistry–based secretome analysis	11
The TLR/MyD88 signalling cascade in inflammation and gastric cancer: the immune regulatory network of Helicobacter pylori	11
Expression of PKM2 in wound keratinocytes is coupled to angiogenesis during skin repair in vivo and in HaCaT keratinocytes in vitro	10
PBX1: a key character of the hallmarks of cancer	10
Microdevices for cancer stem cell culture as a predictive chemotherapeutic response platform	10
Correction to: Arginine derivatives in atrial fibrillation progression phenotypes	10
Interleukin-23 instructs protective multifunctional CD4 T cell responses after immunization with the Mycobacterium tuberculosis subunit vaccine H1 DDA/TDB independently of interleukin-17A	10
Circulating tumor cells in colorectal cancer in the era of precision medicine	10
The interplay of DAMPs, TLR4, and proinflammatory cytokines in pulmonary fibrosis	10
c-Met up-regulates the expression of PD-L1 through MAPK/NF-κBp65 pathway	10
Increased uterine androgen receptor protein abundance results in implantation and mitochondrial defects in pregnant rats with hyperandrogenism and insulin resistance	10
Leukocyte cytokine responses in adult patients with mitochondrial DNA defects	9
TFEB: a double-edged sword for tumor metastasis	9
TGF-β1/Smad3 upregulates UCA1 to promote liver fibrosis through DKK1 and miR18a	9
The osteoporosis susceptibility SNP rs188303909 at 2q14.2 regulates EN1 expression by modulating DNA methylation and E2F6 binding	9
Inhibition of p38 MAPK decreases hyperglycemia-induced nephrin endocytosis and attenuates albuminuria	9
Long noncoding RNA HAR1A regulates oral cancer progression through the alpha-kinase 1, bromodomain 7, and myosin IIA axis	9
Genotypic analysis of a large cohort of patients with suspected atypical hemolytic uremic syndrome	9
Mitochondrial respiration inhibitor enhances the anti-tumor effect of high-dose ascorbic acid in castration-resistant prostate cancer	9
Synergistic effect of the sphingosine kinase inhibitor safingol in combination with 2'-nitroflavone in breast cancer	9
Possible implication of miR-142-3p in coronary microembolization induced myocardial injury via ATXN1L/HDAC3/NOL3 axis	9
Regulation of wound healing and fibrosis by galectins	9
PAX5 aberrant expression incorporated in MIPI-SP risk scoring system exhibits additive value in mantle cell lymphoma	9
Aging whole blood transcriptome reveals candidate genes for SARS-CoV-2-related vascular and immune alterations	9
CREB-H is a stress-regulator of hepcidin gene expression during early postnatal development	9
Altered expression of Sialyl Lewis X in experimental models of Parkinson’s disease	9
ASK1 is a novel molecular target for preventing aminoglycoside-induced hair cell death	8
Correction to: The thyroid status reprograms T cell lymphoma growth and modulates immune cell frequencies	8
Correction to: Local Wnt3a treatment restores bone regeneration in large osseous defects after surgical debridement of osteomyelitis	8
The role of the immunosuppressive PD-1/PD-L1 checkpoint pathway in the aging process and age-related diseases	8
Endothelial glycocalyx degradation in multisystem inflammatory syndrome in children related to COVID-19	8
β-Adrenergic blockade attenuates adverse adipose tissue responses after burn	8
CircRNA CDR1AS promotes cardiac ischemia–reperfusion injury in mice by triggering cardiomyocyte autosis	8
TAT-W61 peptide attenuates neuronal injury through blocking the binding of S100b to the V-domain of Rage during ischemic stroke	8
Extracellular vesicles-associated tRNA-derived fragments (tRFs): biogenesis, biological functions, and their role as potential biomarkers in human diseases	8
Deciphering therapeutic options for neurodegenerative diseases: insights from SIRT1	8
Endotoxin tolerance and low activation of TLR-4/NF-κB axis in monocytes of COVID-19 patients	8
Endocrine resistance in breast cancer: from molecular mechanisms to therapeutic strategies	8
Mesenchymal stem cell–derived extracellular vesicles in periodontal bone repair	8
Correction to: Roles of E3 ubiquitin ligases in gastric cancer carcinogenesis and their effects on cisplatin resistance	8
Pharmacological blockage of the AHR-CYP1A1 axis: a call for in vivo evidence	8
Hepatic microtubule destabilization facilitates liver fibrosis in the mouse model of Wilson disease	8
FDA-approved disulfiram as a novel treatment for aggressive leukemia	8
Acid-sensing ion channel 1a exacerbates renal ischemia–reperfusion injury through the NF-κB/NLRP3 inflammasome pathway	7
Lipid metabolism in idiopathic pulmonary fibrosis: From pathogenesis to therapy	7
Tissue and cell-type-specific transduction using rAAV vectors in lung diseases	7
The role of galectin-3 in atrial fibrillation	7
Current and future direction in treatment of HPV-related cervical disease	7
The transrepression and transactivation roles of CtBPs in the pathogenesis of different diseases	7
Retraction Note: Radiation-induced glucocorticoid receptor promotes CD44 + prostate cancer stem cell growth through activation of SGK1-Wnt/β-catenin signaling	7
Blocking H1R signal aggravates atherosclerosis by promoting inflammation and foam cell formation	7
A coordinated approach for the assessment of molecular subgroups in pediatric ependymomas using low-cost methods	7

MicroRNA signature from extracellular vesicles of HCV/HIV co-infected individuals differs from HCV mono-infected	7
Sphingosine kills Mycobacteria and suppresses mycobacterial lung infections	7
Anti-fibrotic effects of pharmacologic FGF-2: a review of recent literature	7
NF-κB in control of regulatory T cell development, identity, and function	7
How calorie restriction slows aging: an epigenetic perspective	7
The role of CDHR3 in susceptibility to otitis media	7
Regulation of innate lymphoid cell by microbial metabolites	7
Cerebral derailment after myocardial infarct: mechanisms and effects of the signaling from the ischemic heart to brain	6
Functional roles of E3 ubiquitin ligases in prostate cancer	6
Polo-like kinase 2 targeting as novel strategy to sensitize mutant p53-expressing tumor cells to anticancer treatments	6
The role of ceRNAs in breast cancer microenvironmental regulation and therapeutic implications	6
Somatic non-cancerous overgrowth syndrome of obscure molecular etiology: what are the causes and options?	6
Mitochondria targeted esculetin administration improves insulin resistance and hyperglycemia-induced atherosclerosis in db/db mice	6
Ischemic stroke and diabetes: a TLR4-mediated neuroinflammatory perspective	6
Potential role for protein kinase D inhibitors in prostate cancer	6
The ever wider clinical spectrum of RMND1-related disorders and limitedness of phenotype-based classifications	6
Esophageal organoids: applications and future prospects	6
HIF2α regulates the synthesis and release of epinephrine in the adrenal medulla	6
The FOXO family of transcription factors: key molecular players in gastric cancer	6
Hypoxia drives estrogen receptor β-mediated cell growth via transcription activation in non-small cell lung cancer	6
High expression of BCAT1 sensitizes AML cells to PARP inhibitor by suppressing DNA damage response	6
Nucleophosmin/B23 promotes endometrial cancer cell escape from macrophage phagocytosis by increasing CD24 expression	6
RNA-Seq for the detection of gene fusions in solid tumors: development and validation of the JAX FusionSeq™ 2.0 assay	6
Correction to: LncRNA GATA3‑AS1 promoted invasion and migration in human endometrial carcinoma by regulating the miR‑361/ARRB2 axis	6
Correction to: MiR‑30c‑1‑3p targets matrix metalloproteinase 9 involved in the rupture of abdominal aortic aneurysms	6
Spinal fluid IgG antibodies from patients with demyelinating diseases bind multiple sclerosis-associated bacteria	6
Vav2 promotes ductus arteriosus anatomic closure via the remodeling of smooth muscle cells by Rac1 activation	6
Progranulin, a moderator of estrogen/estrogen receptor α binding, regulates bone homeostasis through PERK/p-eIF2 signaling pathway	6
Sphingosine is involved in PAPTP-induced death of pancreas cancer cells by interfering with mitochondrial functions	6
Selective blood-nerve barrier leakiness with claudin-1 and vessel-associated macrophage loss in diabetic polyneuropathy	6
Peroxiredoxins in erythrocytes: far beyond the antioxidant role	6
The serotonin receptor 3E variant is a risk factor for female IBS-D	6
Interaction between mitochondria and microbiota modulating cellular metabolism in inflammatory bowel disease	5
Dysregulation of miRNA-30e-3p targeting IL-1β in an international cohort of systemic autoinflammatory disease patients	5
Revising pathogenesis of AP1S1-related MEDNIK syndrome: a missense variant in the AP1S1 gene as a causal genetic lesion	5
Glycosaminoglycan signatures in body fluids of mucopolysaccharidosis type II mouse model under long-term enzyme replacement therapy	5
New CRISPR/Cas9-based Fgfr2C361Y/+ mouse model of Crouzon syndrome exhibits skull and behavioral abnormalities	5
Progranulin associates with Rab2 and is involved in autophagosome-lysosome fusion in Gaucher disease	5
Hyper-SUMOylation of SMN induced by SENP2 deficiency decreases its stability and leads to spinal muscular atrophy-like pathology	5
Molecular targets in bone cancer pain: a systematic review of inflammatory cytokines	5
Correction to: White and brown adipose tissue functionality is impaired by fine particulate matter (PM2.5) exposure	5
Evaluation of EpCAM-specific exosomal lncRNAs as potential diagnostic biomarkers for lung cancer using droplet digital PCR	5
Myeloid-derived growth factor ameliorates dextran sodium sulfate-induced colitis by regulating macrophage polarization	5
SPP1/osteopontin: a driver of fibrosis and inflammation in degenerative ascending aortic aneurysm?	5
Correction to: ASK1 is a novel molecular target for preventing aminoglycoside‑induced hair cell death	5
Transcription factor EB inhibits non-alcoholic fatty liver disease through fibroblast growth factor 21	5
The crosstalk between ubiquitination and endocrine therapy	5
ATF3 in atherosclerosis: a controversial transcription factor	5
Ebola virus–like particles reprogram cellular metabolism	5
NLRC3 attenuates osteoclastogenesis by limiting TNFα+ Th17 cell response in osteoporosis	5
Periostin secreted by cancer-associated fibroblasts promotes cancer progression and drug resistance in non-small cell lung cancer	5
Correction to: Antioxidative effects of polypyrimidine tract-binding protein-associated splicing factor against pathological retinal angiogenesis through promotion of mitochondrial function	5
Interferons as negative regulators of ILC2s in allergic lung inflammation and respiratory viral infections	5
The role of circular RNA targeting IGF2BPs in cancer—a potential target for cancer therapy	5
Extracellular matrix remodeling in animal models of anthracycline-induced cardiomyopathy: a meta-analysis	5
COVID-19 in multiple-myeloma patients: cellular and humoral immunity against SARS-CoV-2 in a short- and long-term view	5
Predictive value of common genetic variants in idiopathic pulmonary fibrosis survival	5
Non-coding RNAs in Wilms’ tumor: biological function, mechanism, and clinical implications	5
Correction to: Translation of curative therapy concepts with T cell and cytokine antibody combinations for type 1 diabetes reversal in the IDDM rat	5
Umbelliferone alleviates impaired wound healing and skin barrier dysfunction in high glucose-exposed dermal fibroblasts and diabetic skins	4
ADAMTS-7 deficiency attenuates thoracic aortic aneurysm and dissection in mice	4
Serum exosomal coronin 1A and dynamin 2 as neural tube defect biomarkers	4
Progress in diagnosis and treatment of Leber’s hereditary optic neuropathy	4
Glucose enrichment reduces lifespan and promotes tau phosphorylation in human tau-expressing C. elegans, unaffected by O-β-GlcNAcylation induction	4
Targeting ferroptosis for the treatment of female reproductive system disorders	4
An atlas of genome-wide gene expression and metabolite associations and possible mediation effects towards body mass index	4
The role of lncRNA in the differentiation of adipose-derived stem cells: from functions to mechanism	4
Current treatment of Psoriasis triggered by Cytokine Storm and future immunomodulation strategies	4
Deciphering metabolic shifts in Gaucher disease type 1: a multi-omics study	4
Correction to: Liquid biopsies for multiple myeloma in a time of precision medicine	4
White and brown adipose tissue functionality is impaired by fine particulate matter (PM2.5) exposure	4
Macrophage co-culture promotes cell reprogramming and prevents ferroptosis in aging fibroblasts for neurodegeneration therapy	4
Clinical significance of mutational variants in beta and alpha genes in patients with hemoglobinopathies from two large Greek centers: a complex interplay between genotype and phenotype	4
Dual roles of UPRer and UPRmt in neurodegenerative diseases	4
DNA origami: a tool to evaluate and harness transcription factors	4
Phosphorylation of RGS16 at Tyr168 promote HBeAg-mediated macrophage activation by ERK pathway to accelerate liver injury	4
Circular RNAs: Regulators of endothelial cell dysfunction in atherosclerosis	4
Prefrontal cortex astrocytes in major depressive disorder: exploring pathogenic mechanisms and potential therapeutic targets	4
Correction to: Downregulation of microRNA-193a-3p is involved in invertebral disc degeneration by targeting MMP14	4
Regulatory role of annexin A1 in NLRP3 inflammasome activation in atopic dermatitis: insights from keratinocytes in human and murine studies	4
Evaluation of drug sensitivity, immunological characteristics, and prognosis in melanoma patients using an endoplasmic reticulum stress-associated signature based on bioinformatics and pan-cancer anal	4
The plasma exosomes from patients with primary Sjögren’s syndrome contain epithelial cell–derived proteins involved in ferroptosis	4